Anatolian Current Medical Journal最新文献

{"title":"The association of anemia and high neutrophil-lymphocyte ratio with decreased survival in patients with laryngeal cancer treated with radiotherapy","authors":"Ela Delikgöz Soykut, Y. Kemal, Serkan Kaplan, C. Karaçin, E. Odabaşi, A. Unal, Zehra Er, S. AYTAÇ ARSLAN, Y. Guney","doi":"10.38053/acmj.1290362","DOIUrl":"https://doi.org/10.38053/acmj.1290362","url":null,"abstract":"Aims: We aimed to examine the prognostic value of inflammatory markers such as neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR), systemic immune-inflammation index (SII), and anemia on oncological outcomes in patients with laryngeal squamous cell carcinomas (LSCC) treated with radiotherapy. \u0000Methods: 213 LSCC patients analyzed retrospectively. Inflammatory markers were established by examining blood samples taken within 7 days before treatment. Patients were categorized into two groups: low and high according to NLR, PLR, and SII threshold values. In addition, to evaluate the effect of hemoglobin (Hb) level, the threshold value of each inflammatory marker and Hb level were combined, and 3 groups were formed (3 groups for NLR, 3 groups for PLR, and 3 groups for SII). The relationship between inflammatory markers and overall survival (OS), disease-free survival (DFS), and local regional recurrence-free survival (LRRFS) was investigated. \u0000Results: In univariate analysis, high NLR, PLR, SII, and low Hb (","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"135 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130699489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of proton pump inhibitor use on the biodistribution of FDG in patients undergoing 18F FDG PET/CT imaging","authors":"İ. Kaplan, Y. Güzel, C. Can, C. Gündoğan, M. S. Yıldırım, F. Kepenek, B. Taşdemir, H. Kömek","doi":"10.38053/acmj.1241530","DOIUrl":"https://doi.org/10.38053/acmj.1241530","url":null,"abstract":"Aim: In this study, we aimed to investigate the effects of proton pump inhibitors (PPIs) administered shortly before intravenous (iv) F-18 fluorodeoxyglucose (FDG) injection on the physiological FDG uptake in the gastrointestinal tract (GIS) of patients undergoing F-18 FDG positron emission tomography/computed tomography (PET/CT) for oncological purposes. \u0000Material and Method: We retrospectively evaluated 350 patients who underwent 18F-FDG PET/CT in our clinic between November 2020 and June 2021. Among these, 178 patients were given iv PPIs before the scan and the remaining 172 patients with similar characteristics were not. FDG uptake in the gastrointestinal tract was analyzed visually and quantitatively. \u0000Results: The mean age of the patients was 51.7±15 years. There was no significant difference between the two groups in terms of age and gender. Quantitative evaluation revealed that the FDG uptakes in the stomach, duodenum, ileum, and transverse colon and their ratio to hepatic uptake were significantly lower in the group receiving iv PPIs (p","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125402461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of antibiotic resistance rates of Escherichia coli and Klebsiella pneumoniae isolates, which are the causative agents of urinary tract infection in pregnant women","authors":"Suheyla Aydogmus, Esra Kaya Kılıç","doi":"10.38053/acmj.1240882","DOIUrl":"https://doi.org/10.38053/acmj.1240882","url":null,"abstract":"Aim: Urinary tract infections are common infections during pregnancy. Infections seen during pregnancy have a spectrum ranging from asymptomatic bacteriuria to cystitis, pyelonephritis and, urosepsis. In this study, it was aimed to determine the antibiotic resistance rates of Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) isolates isolated from urinary cultures of pregnant women who applied to the Ankara Training and Research Hospital. \u0000Material and Method: The identification and antibiotic susceptibility of E. coli and K. pneumoniae isolates isolated from urinary samples of pregnant women who applied to the Ankara Training and Research Hospital between January 2021 and December 2022 were investigated with VITEK-2 (Biomerioux, France) fully automated system, and the presence of extended-spectrum beta-lactamase (ESBL) was investigated by combined disc diffusion method. The obtained data were analysed retrospectively. \u0000Results: Bacterial growth was detected in 1090 (1.2%) out of a total of 8923 urine samples over a two-year period. 480 (4.4%) of the microbial agents reproducing in urine culture were E. coli and 105 (0.96%) were K. pneumoniae. The rate of extended-spectrum beta-lactamase (ESBL) in E. coli strains was 16.04% (77/480), and the rate of ESBL in K. pneumoniae strains was 20.9% (22/105). Resistance rates of amoxicillin-clavulanic acid, ceftriaxone, phosphomycin, ciprofloxacin, piperacillin-tazobactam, nitrofurantoin, imipenem, meropenem, ertapenem in ESBL negative E. coli strains were 15.9%, 8.82%, 20%, 11.1%, 5.88%, 0%, 0%, 0% and 0%, respectively. Resistance rates of amoxicillin-clavulanic acid, ceftriaxone, phosphomycin, ciprofloxacin, piperacillin-tazobactam, nitrofurantoin, imipenem, meropenem, ertapenem in ESBL positive E. coli strains were determined as 66.5%, 100%, 2.2%, 33.8%, 11.5%, 0%, 0%, 0% and, 0%, respectively. Resistance rates of amoxicillin-clavulanic acid, ceftriaxone, phosphomycin, ciprofloxacin, piperacillin-tazobactam, nitrofurantoin, imipenem, meropenem, ertapenem in ESBL negative K. pneumoniae strains were 53%, 100%, 12.5%, 28.5%, 2.2%, 3.5%, 0%, 0% and, 4.5%, respectively. Resistance rates of amoxicillin-clavulanic acid, ceftriaxone, phosphomycin, nitrofurantoin, ciprofloxacin, piperacillin-tazobactam, imipenem, meropenem, ertapenem in ESBL positive K. pneumoniae strains were 62.5%, 100%, 12.5%, 35%, 28.5%, 22.7%, 0%, 0% and, 4.5%, respectively. \u0000Conclusion: According to the antibiotic susceptibility data in our hospital, phosphomycin or carbapenems may be preferred due to the low resistance rate in the empirical treatment of E. coli-related urinary tract infections in pregnant women. In the treatment of urinary tract infections due to K. pneumoniae, phosphomycin, piperacillin-tazobactam or carbapenems may be preferred due to low resistance rates.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115206189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced age; not a contraindiction for resections of colorectal liver metastasis recurrence","authors":"R. Sönmez","doi":"10.38053/acmj.1257547","DOIUrl":"https://doi.org/10.38053/acmj.1257547","url":null,"abstract":"Aim: The influence of advanced age on the outcome of repeat resections performed for colorectal liver metastasis (CLM) is ill-defined. We aimed to evaluate the safety and efficacy of repeat resections performed for the recurrence of CLMs in younger (≤70 years) and elderly patients (70< years), and to define predictive factors of survival. \u0000Material and Method: A prospectively maintained database of a single center including 291 CLM patients between 1998 and 2019 was analyzed retrospectively. Short and long-term outcomes were compared among younger (n=99, 34%) and elderly (n=192, 66%) patient groups who were treated by repeat resections for CLM recurrence. \u0000Results: Although statistically not significant, analysis of different age groups (≤70, 70-75, 75-80, and 80< years) have given similar results in terms of 1, 3, and 5-year survival (p=0.143). Globally curative resection was validated as a determinant factor in the estimation of survival following resections performed for recurrences according to multivariate analysis (p","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"135 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115892083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the effects of the COVID-19 pandemic on obstetric anesthesia and perioperative outcomes in cesarean section surgery","authors":"L. Kutlucan, Ömer Faruk Altaş, N. Şenoğlu","doi":"10.38053/acmj.1232318","DOIUrl":"https://doi.org/10.38053/acmj.1232318","url":null,"abstract":"Aim: In the literature, studies comparing the preferred anesthesia methods and related parameters in obstetric anesthesia during the pandemic period with the pre-pandemic period are limited. I n this study, primarily in patients who gave birth by cesarean section before and during the COVID-19 (Coronavirus disease 19) pandemic; It was aimed to evaluate the anesthesia method, postoperative complications, length of hospital stay, clinical urgency of the patients and ASA (American Society of Anesthesiologists) scores. In addition, in patients who underwent cesarean section with positive and negative PCR (Polymerase Chain Reaction) tests during the COVID-19 pandemic; It was aimed to evaluate the anesthesia method, postoperative complications, hospital stay, clinical urgency of the cases and ASA scores. \u0000Material and Method: In this retrospective, single-center study, we noted down and compared types of cesarean section (elective or emergency), anesthesia techniques (spinal, spinal+epidural, or general anesthesia), and patients’ ages, ASA scores, PCR test results, postoperative complications (e.g., pneumonia, excessive postpartum bleeding), and lengths of hospital stay. \u0000Results: We carried out this study with the data of 2,406 women, 1,458 of whom gave birth before the pandemic. The findings revealed that the rate of developing complications, the length of hospital stay, the number of patients with an ASA score of 3 and above, and the use of spinal anesthesia significantly increased during the pandemic. Moreover, 182 women were COVID-19-positive among a total of 948 applicants during the pandemic. Although the ASA scores and complication rates were significantly higher among those with a positive PCR test result, the length of hospital stay was similar between the patients by their PCR test results. \u0000Conclusion: Our findings revealed a significant decrease in spinal + epidural anesthesia, which was frequently adopted before, in cases with cesarean section during the pandemic. Spinal anesthesia was mostly used alone. Despite increased complication rates in PCR-positive patients with higher ASA scores undergoing cesarean section, we concluded no significant change in the length of hospital stay. In cases of increased risk of infection and transmission (e.g., pandemic), neuraxial blocks may be preferred as an anesthesia technique to minimize the risk of infection in emergency obstetric operations. It should also be noted that the risk of developing postoperative complications always be high during pandemics.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114352915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of extremity and pelvis traumas admitted to the emergency department before and during the pandemic; with laboratory, embolism and mortality data","authors":"Burak Demirci, A. Coşkun","doi":"10.38053/acmj.1214890","DOIUrl":"https://doi.org/10.38053/acmj.1214890","url":null,"abstract":"Aim: The purpose of this study was to determine the forms of trauma, demographic features, embolism status and mortality of patients who presented to the emergency department due to extremity and pelvis trauma before and during the pandemic period. \u0000Material and Method: This retrospective study included 319 patients, who presented to the emergency department due to trauma between January 1, 2019, and December 31, 2020. The associations between embolism and mortality after trauma, as well as COVID-19, were investigated. \u0000Results: The mean age of the 319 patients was 55.11±19.02 years, the distribution was 19-90 years and 133 (41.7%) were women. It was determined that 171 (53.7%) of the trauma patients were in the pre-pandemic period and 148(46.3%) were in the pandemic period. Embolism was detected in 19 (11.1%) cases before the pandemic and in 35 (23.6%) cases during the pandemic (p=0.003). Pre-pandemic mortality was observed in 10(5.8%) cases, and in pandemic 21 (14.2%) cases (p=0.010). While embolism was present in 22 (71%) cases in the mortality group, it was not observed in 9(29%) cases (p=0.001). \u0000Conclusion: COVID-19 infection and pandemic can adversely affect the incidence of trauma, embolism and mortality. Embolism and mortality rates have increased significantly with the effects of COVID-19 during the pandemic period.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"153 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114642111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Idiopathic axillary web syndrome: a case-based review of an unusual disorder","authors":"İsa Cüce, Sinem Kübra Konca, Rıdvan Yildizhan, I. Kafadar, H. Demir","doi":"10.38053/acmj.1234563","DOIUrl":"https://doi.org/10.38053/acmj.1234563","url":null,"abstract":"Axillary web syndrome (AWS), which frequently develops following axillary lymph node dissection, can also be caused by several other conditions, such as infection or strenuous exercise. In recent years, idiopathic cases have also been reported. We report the case of a 27-year-old female who presented with pain, tension and a taut rope-like structure in the left armpit area. She also had a limited shoulder range of motion in abduction and forward flexion. We diagnosed the patient with idiopathic AWS based on a detailed clinical history and manifestations. The patient completely recovered without any sequelae by therapeutic interventions, including nonsteroidal anti-inflammatory drugs and physical therapy. Through a systematic review of the literature, four additional cases of idiopathic AWS were identified. This study aimed to investigate the similarities and differences between idiopathic and typical AWS cases.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"194 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121867403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient satisfaction, sexual function and decision regret in use of levonorgestrel intrauterine device","authors":"Canan Satır Özel, Gökçem Büşra İNANÇ KARAMAN, Ergul Demircivi, O. Yardimci, Mustafa Çakir, A. Turgut","doi":"10.38053/acmj.1245399","DOIUrl":"https://doi.org/10.38053/acmj.1245399","url":null,"abstract":"Aim: Abnormal uterine bleeding is a common condition. The etiological cause and treatments are diverse. LNG-IUD can be used to treat abnormal uterine bleeding.It has been shown to reduce the amount of bleeding in patients with menorrhagia and increase hemoglobin and hematocrit (Hct) values. The aim is to investigate the effects of LNG-IUD on hemoglobin, Hct, bleeding pattern, and its effect on sexual function, decision regret, and menorrhagia effects according to the etiologic cause. Material and Method: Our study included patients who underwent LNG-IUD implantation and had been using it for over six months. Patients with a history of postmenopausal or adolescent bleeding, hematologic or oncologic diseases, and a history of drug use that may cause coagulation disorders were excluded. Patients were grouped according to their indications as polyp (n=26), adenomyosis (n=16), leiomyoma (n=27), hyperplasia (n=18), and non-structural causes (n=81). Hemoglobin (Hb) and Hct values were examined before and after the application, and bleeding patterns were questioned. Participants were administered Menorrhagia Impact Questionnaire (MIQ), Arizona Sexual Experience Scale and Decision Regret Scale. Results: 168 patients were included in our study. The average duration of LNG-IUD use was 627.0±319 days and the average age was 43.4±6.1 years. The frequency of bleeding (number of bleedings per year) was 18.0±8.0 before LNG-IUD application and 7.8±8.0 after treatment (p","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114145361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The frequency of co-positivity of anti-smooth muscle antibody and anti-nuclear antibodies and their contribution to the diagnosis of autoimmune hepatitis","authors":"Neval Yurttutan Uyar","doi":"10.38053/acmj.1250769","DOIUrl":"https://doi.org/10.38053/acmj.1250769","url":null,"abstract":"Aim: Autoimmune hepatitis (AIH) is a chronic disease observed especially in women. The International Autoimmune Hepatitis Group recommends scoring systems for diagnosis using clinical and laboratory data. All scoring systems gave points to autoantibodies as anti-nuclear antibody (ANA) and anti-smooth muscle antibody (SMA) positivity. This study investigates the impact of the co-positivity of the ANA and SMA antibodies on the autoimmune hepatitis diagnosis. \u0000Material and Method: We monitored 78 autoimmune liver disease (autoimmune hepatitis, AIH) suspected patients with positive SMA antibody and then further tested for ANA between 2014 and2021. SMA test was screened at 1/40 and 1/100 titers and patients who were positive were taken to further dilution. The ANA test was screened at a titer of 1/40 and 1/160, a positive result was found to be repeated with advanced dilutions. All patients’ autoantibody scores of simplified AIH diagnostic system were calculated. \u0000Results: Seventy eight patients with positive SMA antibodies screened for ANA test with 1/40 and 1/160 titer, only 2 patients was found to be negative. The most frequently observed ANA pattern is cytoplasmic linear fibrils (68% ). The 95% ANA positive results was examined at a screening titer of 1/160. The 95% SMA positive results was found at a screening titer of 1/100. The autoantibody scores of 76 patients were +2, patient’s scores were +1. \u0000Conclusion: SMA antibody positivity is accompanied by a high rate of ANA antibody positivity but the co-positivity didn’t effect diagnostic score systems. On the other the co-positivity could be a sign of another associated autoimmune diseases.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127080309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of ADC histogram analysis in the diagnosis of pediatric malignant lymphadenopathy","authors":"Turgut Seber, Tuğba Uylar Seber, E. Aktaş, F. Mutlu, Veysel Gök, Şuayip Keski̇n, Fatoş Tekelioğlu, A. Tasdemir","doi":"10.38053/acmj.1240036","DOIUrl":"https://doi.org/10.38053/acmj.1240036","url":null,"abstract":"Aim: Lymphadenopathy (LAP) is one of the most common daily practice clinical findings in children. LAPs that involve more than one region and do not decrease with treatment are a significant cause of anxiety for clinicians and families. In this occurence, ultrasonography, which is the primary imaging method, is insufficient in some cases. Our aim is to make histopathological predictions with apparent diffusion coefficient (ADC) histogram analysis. \u0000Material and Method: A total of thirty-one patients, seventeen male and fourteen female, who underwent magnetic resonance imaging and were diagnosed histopathologically (with tru-cut or excisional biopsy) were included in our study. Magnetic resonance imagings were evaluated retrospectively. \u0000Results: We could not differentiate lymphoma (when considered as a single group), granulomatous LAP and reactive lymphoid hyperplasia with an ADC histogram analysis (p>0.05). However, when the lymphoma subgroups were evaluated separately, we could only distinguish Burkitt’s lymphoma (with ADCmin values) from other pathologies (p","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129694860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}