Pub Date : 2016-06-27DOI: 10.21776/UB.MNJ.2016.002.02.3
B. Munir, Arief Alamsyah Nasution, Yeni Purnamasari
Background. Stroke is a functional disorder of the brain that occurs suddenly with signs and symptoms of both focal and global clinical lasting more than 24 hours, or can lead to death due to circulatory disorders of the brain. Stroke ranks third leading cause of death in Indonesia. Someone with stroke will leading mood disruption that would cause a depression. Objective. To determine the effect on depression of stroke infarction. Methods. The study used descriptive analytic cross-sectional study. 42 samples was selected by consecutive method. The distribution of the sample are 18 males and 24 females, 23 samples below 60 years and 19 samples over 60 years, 13 samples had duration of suffering a stroke less than 6 months and 29 samples above 6 months. The independent variables in this study were age, sex, and duration of suffering a stroke, while the depression is the dependent variable. Depression was assessed using the Hamilton Depression Rating Scale (HDRS). Results. The results used logistic regression test obtained value of (p = 0.021) is significant in age. Conclusion. The age is the determinant affecting the quality of life after stroke infarction.
{"title":"DETERMINANTS AFFECTING THE DEPRESSION OF INFARCTION POST STROKE PATIENTS IN (SAIFUL ANWAR HOSPITAL MALANG)","authors":"B. Munir, Arief Alamsyah Nasution, Yeni Purnamasari","doi":"10.21776/UB.MNJ.2016.002.02.3","DOIUrl":"https://doi.org/10.21776/UB.MNJ.2016.002.02.3","url":null,"abstract":"Background. Stroke is a functional disorder of the brain that occurs suddenly with signs and symptoms of both focal and global clinical lasting more than 24 hours, or can lead to death due to circulatory disorders of the brain. Stroke ranks third leading cause of death in Indonesia. Someone with stroke will leading mood disruption that would cause a depression. Objective. To determine the effect on depression of stroke infarction. Methods. The study used descriptive analytic cross-sectional study. 42 samples was selected by consecutive method. The distribution of the sample are 18 males and 24 females, 23 samples below 60 years and 19 samples over 60 years, 13 samples had duration of suffering a stroke less than 6 months and 29 samples above 6 months. The independent variables in this study were age, sex, and duration of suffering a stroke, while the depression is the dependent variable. Depression was assessed using the Hamilton Depression Rating Scale (HDRS). Results. The results used logistic regression test obtained value of (p = 0.021) is significant in age. Conclusion. The age is the determinant affecting the quality of life after stroke infarction.","PeriodicalId":31552,"journal":{"name":"Malang Neurology Journal","volume":"2 1","pages":"60-63"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68324570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-27DOI: 10.21776/UB.MNJ.2016.002.02.1
M. R. Indra, C. P. Gasmara
Background. UCAO (Unilateral Cerebral Artery Occlusion) is a stroke induction method by ligating mice’s carotid artery for 45 minutes. Thus giving a hypoxic condition similar to stroke attacks to human. This method is less complicated and far more efficient. MMP-9 is a stroke marker which is assayed by ELISA from the blood of test animal. Objective. To prove UCAO method is capable to raise MMP-9 concentration in mice’s blood. Methods. This research was an experimental laboratory research with post-test only controlled group design. 8 male rats (8-10 weeks) were divided into 2 groups. A day after the treatment group had been induced to stroke, both group were tested to measure the MMP-9 blood concentration through ELISA. Results. In this research, UCAO method had increased MMP-9 blood concentration in treatment group, compared to the control group. It is proved by the statistic tests, Mann-Whitney and Kruskal-Wallis, which showed a significant increase in treatment group (p < 0.05). Conclusion. UCAO method is accepted as a method to create an ischemic stroke mice model.
{"title":"UCAO (UNILATERAL CEREBRAL ARTERY OCCLUSSION) METHOD INCREASES THE LEVEL OF MMP- 9 BRAIN TISSUE IN RATS MODEL OF ISCHEMIC STROKE","authors":"M. R. Indra, C. P. Gasmara","doi":"10.21776/UB.MNJ.2016.002.02.1","DOIUrl":"https://doi.org/10.21776/UB.MNJ.2016.002.02.1","url":null,"abstract":"Background. UCAO (Unilateral Cerebral Artery Occlusion) is a stroke induction method by ligating mice’s carotid artery for 45 minutes. Thus giving a hypoxic condition similar to stroke attacks to human. This method is less complicated and far more efficient. MMP-9 is a stroke marker which is assayed by ELISA from the blood of test animal. Objective. To prove UCAO method is capable to raise MMP-9 concentration in mice’s blood. Methods. This research was an experimental laboratory research with post-test only controlled group design. 8 male rats (8-10 weeks) were divided into 2 groups. A day after the treatment group had been induced to stroke, both group were tested to measure the MMP-9 blood concentration through ELISA. Results. In this research, UCAO method had increased MMP-9 blood concentration in treatment group, compared to the control group. It is proved by the statistic tests, Mann-Whitney and Kruskal-Wallis, which showed a significant increase in treatment group (p < 0.05). Conclusion. UCAO method is accepted as a method to create an ischemic stroke mice model.","PeriodicalId":31552,"journal":{"name":"Malang Neurology Journal","volume":"2 1","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68323898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-27DOI: 10.21776/UB.MNJ.2016.002.02.7
H. Hidayati
Headache is one of the most common complaints presenting to primary care physicians, as well as neurologists. Although the vast majority of headache syndromes are benign, clinicians are faced with the crucial task of differentiating benign headache disorders from potentially life threatening headache. Given the broad range of disorders that present with headache, a focused and systematic approach is necessary to facilitate the prompt diagnosis and treatment of various kinds of head pain.
{"title":"THE CLINICIAN'S APPROACH TO THE MANAGEMENT OF HEADACHE","authors":"H. Hidayati","doi":"10.21776/UB.MNJ.2016.002.02.7","DOIUrl":"https://doi.org/10.21776/UB.MNJ.2016.002.02.7","url":null,"abstract":"Headache is one of the most common complaints presenting to primary care physicians, as well as neurologists. Although the vast majority of headache syndromes are benign, clinicians are faced with the crucial task of differentiating benign headache disorders from potentially life threatening headache. Given the broad range of disorders that present with headache, a focused and systematic approach is necessary to facilitate the prompt diagnosis and treatment of various kinds of head pain.","PeriodicalId":31552,"journal":{"name":"Malang Neurology Journal","volume":"2 1","pages":"89-96"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68324459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-27DOI: 10.21776/UB.MNJ.2016.002.02.4
Achdiat Agoes, Retno Lestari, Saifullah Alfaruqi
Background. The concept of cognitive (from Latin cognosere, to know or to recognize) refers to the ability to process information, applying knowledge, and change the trend. cognitive function of the elderly can be optimized through a variety of ways, one of that way is the brain training game (Brain Age). The game was created specifically to train the cognitive function of elderly. Objective. To determine the effect of Brain Ag) to the improvement of cognitive function in the elderly in Malang. Methods. Quasi-experimental pretest-posttest approach, the treatment and control groups, and the sampling is done with purposive sampling to obtain the 20 respondents. Data collection instrument in this study are in general cognitive tests by using a measuring instrument MMSE. Then the data were analyzed by Mann-Whitney test showed p value 0.000 <α 0.05. Results. There is the effect of therapy brain training game (Brain Age) on increasing cognitive function of elderly in Malang. Conclusion. Therapy of brain training game (Brain Age) can be used as an alternative method of nursing actions that can be implemented in nursing geriatric and to consider inter-community cooperation between the elderly or nursing home.
{"title":"EFFECTS OF BRAIN AGE TO INCREASE COGNITIVE FUNCTION IN ELDERLY","authors":"Achdiat Agoes, Retno Lestari, Saifullah Alfaruqi","doi":"10.21776/UB.MNJ.2016.002.02.4","DOIUrl":"https://doi.org/10.21776/UB.MNJ.2016.002.02.4","url":null,"abstract":"Background. The concept of cognitive (from Latin cognosere, to know or to recognize) refers to the ability to process information, applying knowledge, and change the trend. cognitive function of the elderly can be optimized through a variety of ways, one of that way is the brain training game (Brain Age). The game was created specifically to train the cognitive function of elderly. Objective. To determine the effect of Brain Ag) to the improvement of cognitive function in the elderly in Malang. Methods. Quasi-experimental pretest-posttest approach, the treatment and control groups, and the sampling is done with purposive sampling to obtain the 20 respondents. Data collection instrument in this study are in general cognitive tests by using a measuring instrument MMSE. Then the data were analyzed by Mann-Whitney test showed p value 0.000 <α 0.05. Results. There is the effect of therapy brain training game (Brain Age) on increasing cognitive function of elderly in Malang. Conclusion. Therapy of brain training game (Brain Age) can be used as an alternative method of nursing actions that can be implemented in nursing geriatric and to consider inter-community cooperation between the elderly or nursing home.","PeriodicalId":31552,"journal":{"name":"Malang Neurology Journal","volume":"22 1","pages":"63-69"},"PeriodicalIF":0.0,"publicationDate":"2016-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68324624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.21776/UB.MNJ.2016.002.01.7
S. Ratnaningrum
Carbamazepine as an antiepileptic drug that is used widely and was known can cause severe cutaneous adverse drug reactions like SJS-TEN. These adverse drug reactions is known to be associated with some specific HLA polymorphism in European populations (HLA-A*31: 01), China (HLA-A*31: 01; HLA-B*15: 02), Japan (HLA-A*31 : 01; HLA-B*15: 11), Korea HLA-A*31: 01; HLA-B*15: 02; HLA-B*15: 11), India (HLA-B*15: 02), Thailand (HLA-B*15: 02), and Malaysia (HLA-B*15: 02). Information related to certain HLA polymorphism is important to prevent adverse drug reaction but there is no sufficient data on the population of Indonesia.
卡马西平作为一种广泛使用的抗癫痫药物，已知可引起严重的皮肤不良反应，如SJS-TEN。已知这些药物不良反应与欧洲人群(HLA- a * 31:01)、中国人群(HLA- a * 31:01;HLA-B* 15:02)，日本(HLA-A* 31:01;HLA-B* 15:11)，韩国HLA-A* 31:01;HLA-B * 15: 02;HLA-B* 15:11)、印度(HLA-B* 15:02)、泰国(HLA-B* 15:02)、马来西亚(HLA-B* 15:02)。与某些HLA多态性相关的信息对预防药物不良反应很重要，但在印度尼西亚人口中没有足够的数据。
{"title":"ASSOCIATION BETWEEN CARBAMAZEPINE INDUCED SEVERE CUTANEOUS ADVERSE DRUG REACTION AND HLA POLIMORPHISMS","authors":"S. Ratnaningrum","doi":"10.21776/UB.MNJ.2016.002.01.7","DOIUrl":"https://doi.org/10.21776/UB.MNJ.2016.002.01.7","url":null,"abstract":"Carbamazepine as an antiepileptic drug that is used widely and was known can cause severe cutaneous adverse drug reactions like SJS-TEN. These adverse drug reactions is known to be associated with some specific HLA polymorphism in European populations (HLA-A*31: 01), China (HLA-A*31: 01; HLA-B*15: 02), Japan (HLA-A*31 : 01; HLA-B*15: 11), Korea HLA-A*31: 01; HLA-B*15: 02; HLA-B*15: 11), India (HLA-B*15: 02), Thailand (HLA-B*15: 02), and Malaysia (HLA-B*15: 02). Information related to certain HLA polymorphism is important to prevent adverse drug reaction but there is no sufficient data on the population of Indonesia.","PeriodicalId":31552,"journal":{"name":"Malang Neurology Journal","volume":"2 1","pages":"40-46"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68323884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.21776/UB.MNJ.2016.002.01.4
Zanella Yolanda Lie, Meliantha Tandiono, Lucy Pricillia, Astrid Nandikasari Lukito, C. P. Gasmara
Background. Ischemic stroke can cause hypoxia in brain tissue and damage the neuron. The defense ability and plasticity is activated by ERK1/2 pathway. Grape peel and seed extract (Vitis vinifera can induce release neurotrophic factor that contribute in ERK1/2 pathway mechanism. Objective. To prove that grape peel and seed extract can regenerate neuron in anatomical and functional view. Methods. This research use true experimental design with sample in this research is 20 male 8-10 weeks old wistar strain rats which are induced stroke by internal and external carotid artery occlusion method. Results. The repairment is monitored from four parameters, namely cylinder test score, ladder rung walking test score, extensive infarct volume, and number of damaged neuron. Conclusion. The result is 50mg/KgBW is effective in repairing neuron. It is seen from the result of improvement in four parameters explained above.
{"title":"BRAIN NEURON REGENERATION IN POST-STROKE REHABILITATION TREATMENT USING GRAPE PEEL AND SEED EXTRACT (Vitis vinifera) IN INDUCING ERK1 / 2 PATHWAY","authors":"Zanella Yolanda Lie, Meliantha Tandiono, Lucy Pricillia, Astrid Nandikasari Lukito, C. P. Gasmara","doi":"10.21776/UB.MNJ.2016.002.01.4","DOIUrl":"https://doi.org/10.21776/UB.MNJ.2016.002.01.4","url":null,"abstract":"Background. Ischemic stroke can cause hypoxia in brain tissue and damage the neuron. The defense ability and plasticity is activated by ERK1/2 pathway. Grape peel and seed extract (Vitis vinifera can induce release neurotrophic factor that contribute in ERK1/2 pathway mechanism. Objective. To prove that grape peel and seed extract can regenerate neuron in anatomical and functional view. Methods. This research use true experimental design with sample in this research is 20 male 8-10 weeks old wistar strain rats which are induced stroke by internal and external carotid artery occlusion method. Results. The repairment is monitored from four parameters, namely cylinder test score, ladder rung walking test score, extensive infarct volume, and number of damaged neuron. Conclusion. The result is 50mg/KgBW is effective in repairing neuron. It is seen from the result of improvement in four parameters explained above.","PeriodicalId":31552,"journal":{"name":"Malang Neurology Journal","volume":"2 1","pages":"19-23"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68324108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.21776/UB.MNJ.2016.002.01.1
Ita Muharram Sari, M. Islam
Background. There are limited studies of von Willebrand factor (vWF) and thrombotic stroke, escpecially the relationship between level of vWF and functional neurological deficit. Objective. To determine the difference between functional neurological deficit; measured by the NIHSS scale with the vWF level. Methods. Design study was cross sectional, sampling by consecutive admission according to inclusion and exclusion criteria. Blood samples were taken for vWF measurement. Patients are divided into two categories, low vWF level and high vWF levels. Deficit functional neurologist was measured by NIHSS scale. Results. The results were analyzed by chi square. From 80 patients, the result compares the level of NIHSS scale. In grup with mild NIHSS and low vWF levels (50 %) higher than grup with mild NIHSS and high vWF levels (27,27 %). In other side, grup with moderate NIHSS and low vWF levels (50 %) lower than grup with moderate NIHSS and high vWF levels (72,73 %). The difference is not significant statistically (p=0.067). Conclusion. There was no difference between deficit functional neurologist measured by NIHSS scale with von Willebrand factor levels in acute thrombotic stroke patients.
{"title":"THE COMPARISON BETWEEN DEFICIT FUNCTIONAL NEUROLOGIST WITH VON WILLEBRAND FACTOR LEVELS IN ACUTE THROMBOTIC STROKE PATIENTS","authors":"Ita Muharram Sari, M. Islam","doi":"10.21776/UB.MNJ.2016.002.01.1","DOIUrl":"https://doi.org/10.21776/UB.MNJ.2016.002.01.1","url":null,"abstract":"Background. There are limited studies of von Willebrand factor (vWF) and thrombotic stroke, escpecially the relationship between level of vWF and functional neurological deficit. Objective. To determine the difference between functional neurological deficit; measured by the NIHSS scale with the vWF level. Methods. Design study was cross sectional, sampling by consecutive admission according to inclusion and exclusion criteria. Blood samples were taken for vWF measurement. Patients are divided into two categories, low vWF level and high vWF levels. Deficit functional neurologist was measured by NIHSS scale. Results. The results were analyzed by chi square. From 80 patients, the result compares the level of NIHSS scale. In grup with mild NIHSS and low vWF levels (50 %) higher than grup with mild NIHSS and high vWF levels (27,27 %). In other side, grup with moderate NIHSS and low vWF levels (50 %) lower than grup with moderate NIHSS and high vWF levels (72,73 %). The difference is not significant statistically (p=0.067). Conclusion. There was no difference between deficit functional neurologist measured by NIHSS scale with von Willebrand factor levels in acute thrombotic stroke patients.","PeriodicalId":31552,"journal":{"name":"Malang Neurology Journal","volume":"2 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68323757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.21776/ub.mnj.2016.002.01.2
Masruroh Rahayu, S. Kurniawan, M. Husna, H. Hermawan
Background. One of the regenerative therapy modalities in Parkinson is using the beta glucan effect contained in Saccharomyces cerevisae. Objective. To identify the effect of reduction in alpha synuclein expression on the brain substantia nigra in Parkinson's rat model after given Saccharomyces cerevisae. Methods. This research applied true experimental design by in vivo with draft randomized post test only controlled group design. The sample was divided into five groups, each of them consisted of 5 rats. Variables measured were the decreasing level of alpha synuclein. Results. There was a significant difference between positive control and negative control group. Conclusion. The addition of Saccharomyces cerevisae is able to lower the alpha synuclein expression in Parkinson’s Wistar strain rat models significantly with maximum at the dose of 72 mg/kgBB.
{"title":"THE EFFECT OF BETA GLUCAN OF SACCHAROMYCES CEREVISAE ON THE DECREASE OF ALPHA SYNUCLEIN EXPRESSION IN THE BRAIN SUBSTANTIA NIGRA OF PARKINSON’S WISTAR STRAIN RATS (Rattus novergicus) MODEL INDUCED WITH ROTENONE","authors":"Masruroh Rahayu, S. Kurniawan, M. Husna, H. Hermawan","doi":"10.21776/ub.mnj.2016.002.01.2","DOIUrl":"https://doi.org/10.21776/ub.mnj.2016.002.01.2","url":null,"abstract":"Background. One of the regenerative therapy modalities in Parkinson is using the beta glucan effect contained in Saccharomyces cerevisae. Objective. To identify the effect of reduction in alpha synuclein expression on the brain substantia nigra in Parkinson's rat model after given Saccharomyces cerevisae. Methods. This research applied true experimental design by in vivo with draft randomized post test only controlled group design. The sample was divided into five groups, each of them consisted of 5 rats. Variables measured were the decreasing level of alpha synuclein. Results. There was a significant difference between positive control and negative control group. Conclusion. The addition of Saccharomyces cerevisae is able to lower the alpha synuclein expression in Parkinson’s Wistar strain rat models significantly with maximum at the dose of 72 mg/kgBB.","PeriodicalId":31552,"journal":{"name":"Malang Neurology Journal","volume":"24 1","pages":"9-13"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68323870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.21776/UB.MNJ.2016.002.01.6
S. Kurniawan
The ability to recognize objects and words is not just depend on the integrity of visual pathway and primary vision area on cerebral cortex (Brodmann area 17), but also secondary vision area 18 and tertiary vision area 19 on occipital lobe. Lesion in occipital lobe could disturb of human visual function such as visual field defects, inability to recognize colors, inability to recognize words, visual hallucinations and illusions, occipital lobe epilepsy, and Anton’s syndrome. Some causes of occipital lobe lesion are head trauma, chemical intoxicity, neoplasma, stroke, degenerative disease, and vascular disease. Prognosis of occipital lobe syndrome is depend on the initial condition but prognosis from the majority of cases with occipital lobe lesions is not good because the exact intervention is not discovered yet and included one of irreversible disease.
{"title":"OCCIPITAL LOBE SYNDROME","authors":"S. Kurniawan","doi":"10.21776/UB.MNJ.2016.002.01.6","DOIUrl":"https://doi.org/10.21776/UB.MNJ.2016.002.01.6","url":null,"abstract":"The ability to recognize objects and words is not just depend on the integrity of visual pathway and primary vision area on cerebral cortex (Brodmann area 17), but also secondary vision area 18 and tertiary vision area 19 on occipital lobe. Lesion in occipital lobe could disturb of human visual function such as visual field defects, inability to recognize colors, inability to recognize words, visual hallucinations and illusions, occipital lobe epilepsy, and Anton’s syndrome. Some causes of occipital lobe lesion are head trauma, chemical intoxicity, neoplasma, stroke, degenerative disease, and vascular disease. Prognosis of occipital lobe syndrome is depend on the initial condition but prognosis from the majority of cases with occipital lobe lesions is not good because the exact intervention is not discovered yet and included one of irreversible disease.","PeriodicalId":31552,"journal":{"name":"Malang Neurology Journal","volume":"35 1","pages":"29-38"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68323739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.21776/UB.MNJ.2016.002.01.5
S. Kurniawan, M. Husna, H. Rasyid, Nadiya Elfira Bilqis
Background. Carpal tunnel syndrome (CTS) is caused by entrapment neuropathy of the median nerve in the carpal tunnel that can be detected with electroneuromyography (ENMG). Objective. To determine whether there are significant differences in parameters of ENMG examination between CTS groups with mild-to-moderate and severe clinical symptoms. Methods. The study design was observational analytic using cross sectional design approach of the patient's medical record data as many as 61 samples. Results. From 61 samples, there were dominancy of age ≥ 40 years old as many as 80.32% and gender female as many as 88.52%. There was no significant differences in age and gender between the two groups (p=0.073 and p=1.000 respectively). Sensory amplitude, MSDL, and Ring Diff are significantly different between the two groups (p=0.005, p=0.020, and p=0.031 respectively). There are no significant difference of motor amplitude and MMDL between the two groups (p=0.384 and p=0.196 respectively). Conclusion. Sensory amplitude value having a relationship with the severity of clinical symptoms. ENMG examination and clinical symptoms of CTS were independent parameters, that should not be used alone to make a diagnosi both of them could enhance the accuracy of diagnosis.
{"title":"THE RELATIONSHIP OF CARPAL TUNNEL SYNDROME CLINICAL SYMPTOMPS AND ELECTRONEUROMYOGRAPHY RESULTS IN RSSA MALANG","authors":"S. Kurniawan, M. Husna, H. Rasyid, Nadiya Elfira Bilqis","doi":"10.21776/UB.MNJ.2016.002.01.5","DOIUrl":"https://doi.org/10.21776/UB.MNJ.2016.002.01.5","url":null,"abstract":"Background. Carpal tunnel syndrome (CTS) is caused by entrapment neuropathy of the median nerve in the carpal tunnel that can be detected with electroneuromyography (ENMG). Objective. To determine whether there are significant differences in parameters of ENMG examination between CTS groups with mild-to-moderate and severe clinical symptoms. Methods. The study design was observational analytic using cross sectional design approach of the patient's medical record data as many as 61 samples. Results. From 61 samples, there were dominancy of age ≥ 40 years old as many as 80.32% and gender female as many as 88.52%. There was no significant differences in age and gender between the two groups (p=0.073 and p=1.000 respectively). Sensory amplitude, MSDL, and Ring Diff are significantly different between the two groups (p=0.005, p=0.020, and p=0.031 respectively). There are no significant difference of motor amplitude and MMDL between the two groups (p=0.384 and p=0.196 respectively). Conclusion. Sensory amplitude value having a relationship with the severity of clinical symptoms. ENMG examination and clinical symptoms of CTS were independent parameters, that should not be used alone to make a diagnosi both of them could enhance the accuracy of diagnosis.","PeriodicalId":31552,"journal":{"name":"Malang Neurology Journal","volume":"2 1","pages":"24-29"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68324171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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