Background: Benign paroxysmal positional vertigo (BPPV) is a common clinical condition characterized by sudden, brief paroxysmal attacks of rotation vertigo occurred by changing the head position. BPPV is the most common peripheral vestibular pathology and is found frequently in females. There are very limited data on the association between BPPV and pregnancy. Objective: The objective of this study was to study the BPPV during pregnancy along with details of clinical manifestations and management. Patients and Methods: This is a cross-sectional study where pregnant women with BPPV were enrolled. The study was conducted between April 2020 and May 2022. Detailed neurological examinations were done at the vertigo clinic. Results: There were seven cases of BPPV associated with pregnancy in this study. The most common symptom was rotatory vertigo. All were diagnosed with the Dix–Hallpike test. All underwent Epley maneuver and symptoms resolved. Out of seven cases, two showed low 25-hydroxyvitamin D levels. Conclusion: Vertigo is a morbid symptom during pregnancy that affects both pregnant women and fetal status. To improve the quality of life during gestation, clinicians should consider this BPPV as an important clinical entity in their differential diagnosis of vertigo.
{"title":"Benign paroxysmal positional vertigo in pregnancy: Our experiences at a tertiary care teaching hospital of Eastern India","authors":"S. Swain, S. Vivek","doi":"10.4103/mj.mj_16_22","DOIUrl":"https://doi.org/10.4103/mj.mj_16_22","url":null,"abstract":"Background: Benign paroxysmal positional vertigo (BPPV) is a common clinical condition characterized by sudden, brief paroxysmal attacks of rotation vertigo occurred by changing the head position. BPPV is the most common peripheral vestibular pathology and is found frequently in females. There are very limited data on the association between BPPV and pregnancy. Objective: The objective of this study was to study the BPPV during pregnancy along with details of clinical manifestations and management. Patients and Methods: This is a cross-sectional study where pregnant women with BPPV were enrolled. The study was conducted between April 2020 and May 2022. Detailed neurological examinations were done at the vertigo clinic. Results: There were seven cases of BPPV associated with pregnancy in this study. The most common symptom was rotatory vertigo. All were diagnosed with the Dix–Hallpike test. All underwent Epley maneuver and symptoms resolved. Out of seven cases, two showed low 25-hydroxyvitamin D levels. Conclusion: Vertigo is a morbid symptom during pregnancy that affects both pregnant women and fetal status. To improve the quality of life during gestation, clinicians should consider this BPPV as an important clinical entity in their differential diagnosis of vertigo.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":"21 1","pages":"129 - 133"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48950295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The laterlization of middle turbinate and adhesion to the lateral nasal wall is a common coplication of fuctional endoscopic sinus surgery (FEESS) result in failure of initial procedure and obstruction of osteomeatal complex. Current procedure for middle turbinate medialization, include creation of controlled synaechia between middle turbinate and nasal septum (bolgerization) and fixation of middle turbinate to nasal septum by suturing using absorbale vicryl suture (conchopexy).Objective: Is to compare between FESS with middle turbinate fixation to the septum by conchopexy or bolgerization technique to prevent laterlization of middle turbinate and thier impact on postoperative symptoms and signs and conventional FESS without fixation of the middle turbinate to the septum. Patients and Methods: The current stydy include 80 patients, they were divided into 3 groups, Group 1, include 30 patients underwent conventional FESS with medialization of middle turbinate only, using middle meatal pack, lest for 2 days. Group2, included 25 patients underwent FESS with Bolgerization method. Group3, included 25 patients underwent FESS with conchopexy by suturing the middle turbinate to the septum. Preoperative, postoperative, symptoms and endoscopy findings were compare among all the 3 groups. Result: Significant improvement is achieved in all groups and this improvement was founds to be significant stastically for nasa obstruction,nasal discharge, olfactory function, (P > 0.001)and for facial pain (P = 0.009). Bolgerization technique had better result in improving olfactory disturbance as compared to other methods. The pstoerative endoscopic findings improvement score was stastically significant for all groups with (P = 0.002) for the 1st group and (P = 0.001) fore the 2nd and 3rd groups. Regarding synaechia and laterlization of middle turbinate , in group 3 one of the patient had laterlization and synaechia between the middle turbinate and the lateral nasal wall (4%), 4 patients in group 2 (16%), and 10 patients in group 1 (33.3%). Conclusion: Conchopexy and Bolgerization are effective method to stabilize middle turbinate and preventing middle turbinate laterlization and synaechia following FESS with highly significant improvement of postoperative symptoms and endoscopic findings.
{"title":"The benefit of middle turbinate stabilization during functional endoscopic sinus surgery, A comparative study","authors":"A. Mohammed","doi":"10.4103/mj.mj_5_22","DOIUrl":"https://doi.org/10.4103/mj.mj_5_22","url":null,"abstract":"Background: The laterlization of middle turbinate and adhesion to the lateral nasal wall is a common coplication of fuctional endoscopic sinus surgery (FEESS) result in failure of initial procedure and obstruction of osteomeatal complex. Current procedure for middle turbinate medialization, include creation of controlled synaechia between middle turbinate and nasal septum (bolgerization) and fixation of middle turbinate to nasal septum by suturing using absorbale vicryl suture (conchopexy).Objective: Is to compare between FESS with middle turbinate fixation to the septum by conchopexy or bolgerization technique to prevent laterlization of middle turbinate and thier impact on postoperative symptoms and signs and conventional FESS without fixation of the middle turbinate to the septum. Patients and Methods: The current stydy include 80 patients, they were divided into 3 groups, Group 1, include 30 patients underwent conventional FESS with medialization of middle turbinate only, using middle meatal pack, lest for 2 days. Group2, included 25 patients underwent FESS with Bolgerization method. Group3, included 25 patients underwent FESS with conchopexy by suturing the middle turbinate to the septum. Preoperative, postoperative, symptoms and endoscopy findings were compare among all the 3 groups. Result: Significant improvement is achieved in all groups and this improvement was founds to be significant stastically for nasa obstruction,nasal discharge, olfactory function, (P > 0.001)and for facial pain (P = 0.009). Bolgerization technique had better result in improving olfactory disturbance as compared to other methods. The pstoerative endoscopic findings improvement score was stastically significant for all groups with (P = 0.002) for the 1st group and (P = 0.001) fore the 2nd and 3rd groups. Regarding synaechia and laterlization of middle turbinate , in group 3 one of the patient had laterlization and synaechia between the middle turbinate and the lateral nasal wall (4%), 4 patients in group 2 (16%), and 10 patients in group 1 (33.3%). Conclusion: Conchopexy and Bolgerization are effective method to stabilize middle turbinate and preventing middle turbinate laterlization and synaechia following FESS with highly significant improvement of postoperative symptoms and endoscopic findings.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":"21 1","pages":"160 - 163"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45874036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Entamoeba histolytica is a human enteric protozoan, which is the causative agent of amebiasis. The host activates a series of immunological responses to protect against the parasite after contact with the ameba and further invasion of the gut epithelium layer. As a result, the ameba has developed a variety of evasion mechanisms to hold out the immune response and continue to survive and cause disease. The calreticulin (EhCRT) is one of the immunogenic molecules of E. histolytica that induces an immune response in the human host. Increase in the expression of the EhCRT gene could provide control mechanism that allows the parasite to adapt and survive in host tissues. Aim of the Study: This study was designed to detect the EhCRT gene of E. histolytica by real-time polymerase chain reaction (PCR) in stool samples of children with amebiasis and its roles in host–parasite relationship via measuring the concentration of tumor necrosis factor alpha (TNFα) and interleukin 25 (IL25) by enzyme-linked immunoassay (ELISA) technique in their serum. Materials and Methods: A total of 86 diarrheal fecal samples were collected from children in age <1 year to 13 years suspected to be infected with E. histolytica during the period from December 30, 2020, to September 1, 2021. Microscopically positive samples were the subject to conventional PCR and real-time PCR for the detection of E. histolytica HM1:IMSS strain using (Psp) gene sequences and detection of calreticulin (EhCRT) expression. Blood was withdrawn from each child included in the study for ELISA test to measure the level of IL25 and TNFα. Results: Fecal samples for microscopic examination revealed that 71 (82.6%) children had amebic colitis, E. histolytica gene was detected in 44 samples (71%) using conventional PCR, and the immunogene EhCRT was expressed in 36 stool samples using real-time PCR. The results of the recent study showed highly significant elevation in the level of TNFα and IL25 in the amebic group (Eh+ve PCR). The majority of amebic children were in the age group of 1–4 years, had mucoid, acute, and with primary episodes of diarrhea. Conclusion: E. histolytica is a protozoan parasite highly prevalent among diarrheal children and is responsible for gastrointestinal amebiasis in the human host. The PCR is a useful tool in the diagnosis of E. histolytica infection. It is clear that the expression of the calreticulin gene (EhCRT) concedes with the duration of diarrhea a virulence factor that plays a role in host pathogenic pathways. The findings of this study showed that the level of TNFα in the serum of children infected with amebic colitis (Eh gene + ve) is significantly increased during the course of infection and the cytokine IL25 exhibits a significant drops in the same children.
{"title":"Detection of EhCRT gene expression in Entamoeba histolytica-Infected children and its correlation with interleukin 25 and tumor necrosis factor alpha","authors":"N. Khalaf, H. Khalil, Ahmed Abood","doi":"10.4103/mj.mj_21_22","DOIUrl":"https://doi.org/10.4103/mj.mj_21_22","url":null,"abstract":"Objectives: Entamoeba histolytica is a human enteric protozoan, which is the causative agent of amebiasis. The host activates a series of immunological responses to protect against the parasite after contact with the ameba and further invasion of the gut epithelium layer. As a result, the ameba has developed a variety of evasion mechanisms to hold out the immune response and continue to survive and cause disease. The calreticulin (EhCRT) is one of the immunogenic molecules of E. histolytica that induces an immune response in the human host. Increase in the expression of the EhCRT gene could provide control mechanism that allows the parasite to adapt and survive in host tissues. Aim of the Study: This study was designed to detect the EhCRT gene of E. histolytica by real-time polymerase chain reaction (PCR) in stool samples of children with amebiasis and its roles in host–parasite relationship via measuring the concentration of tumor necrosis factor alpha (TNFα) and interleukin 25 (IL25) by enzyme-linked immunoassay (ELISA) technique in their serum. Materials and Methods: A total of 86 diarrheal fecal samples were collected from children in age <1 year to 13 years suspected to be infected with E. histolytica during the period from December 30, 2020, to September 1, 2021. Microscopically positive samples were the subject to conventional PCR and real-time PCR for the detection of E. histolytica HM1:IMSS strain using (Psp) gene sequences and detection of calreticulin (EhCRT) expression. Blood was withdrawn from each child included in the study for ELISA test to measure the level of IL25 and TNFα. Results: Fecal samples for microscopic examination revealed that 71 (82.6%) children had amebic colitis, E. histolytica gene was detected in 44 samples (71%) using conventional PCR, and the immunogene EhCRT was expressed in 36 stool samples using real-time PCR. The results of the recent study showed highly significant elevation in the level of TNFα and IL25 in the amebic group (Eh+ve PCR). The majority of amebic children were in the age group of 1–4 years, had mucoid, acute, and with primary episodes of diarrhea. Conclusion: E. histolytica is a protozoan parasite highly prevalent among diarrheal children and is responsible for gastrointestinal amebiasis in the human host. The PCR is a useful tool in the diagnosis of E. histolytica infection. It is clear that the expression of the calreticulin gene (EhCRT) concedes with the duration of diarrhea a virulence factor that plays a role in host pathogenic pathways. The findings of this study showed that the level of TNFα in the serum of children infected with amebic colitis (Eh gene + ve) is significantly increased during the course of infection and the cytokine IL25 exhibits a significant drops in the same children.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":"21 1","pages":"164 - 170"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45633628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Diastolic dysfunction (DD) has a high prevalence in the community. Although it often remains asymptomatic, it can be a significant cause of morbidity and mortality. The assessment of the left ventricular diastolic function (DF) should be an integral part of a routine examination, particularly in patients presenting with dyspnea or heart failure. Patients and Methods: A cross-sectional study started from June 2018 to February 2019. The study was conducted in four medical institutions in Baghdad. Mitral inflow for the assessment of left ventricular DF depending on guideline 2016 was performed. Results: Left ventricular ejection fraction (EF) was higher in a group with normal DF than in the group with DD (P = 0.0001). Mean E/A ratio was higher among patients 2.15 ± 0.48 than in the control Group 1.30 ± 0.50 the difference between them was significant (P = 0.0001). Mean acceleration time (AT) was longer in individual with normal DF (88.23 ± 13.85) than that of patients with LVDD (72.89 ± 8.88), while the acceleration rate in LVDD group (1364.38 ± 277.31) was higher than that in normal LVDF (859.12 ± 275.95). There was a significant difference (P = 0.0001) between the two groups. Conclusion: AT and rate were significantly correlated with DD in normal EF group, but both of them have no relation to the grading of DD.
{"title":"Echocardiographic assessment of left ventricle diastolic dysfunction using transmitral doppler acceleration rate of mitral inflow E-Wave","authors":"Adel Alsalman, H. Farhan, Marwa Qasim","doi":"10.4103/mj.mj_37_22","DOIUrl":"https://doi.org/10.4103/mj.mj_37_22","url":null,"abstract":"Background: Diastolic dysfunction (DD) has a high prevalence in the community. Although it often remains asymptomatic, it can be a significant cause of morbidity and mortality. The assessment of the left ventricular diastolic function (DF) should be an integral part of a routine examination, particularly in patients presenting with dyspnea or heart failure. Patients and Methods: A cross-sectional study started from June 2018 to February 2019. The study was conducted in four medical institutions in Baghdad. Mitral inflow for the assessment of left ventricular DF depending on guideline 2016 was performed. Results: Left ventricular ejection fraction (EF) was higher in a group with normal DF than in the group with DD (P = 0.0001). Mean E/A ratio was higher among patients 2.15 ± 0.48 than in the control Group 1.30 ± 0.50 the difference between them was significant (P = 0.0001). Mean acceleration time (AT) was longer in individual with normal DF (88.23 ± 13.85) than that of patients with LVDD (72.89 ± 8.88), while the acceleration rate in LVDD group (1364.38 ± 277.31) was higher than that in normal LVDF (859.12 ± 275.95). There was a significant difference (P = 0.0001) between the two groups. Conclusion: AT and rate were significantly correlated with DD in normal EF group, but both of them have no relation to the grading of DD.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":"21 1","pages":"139 - 144"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46002947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aurobinda Banerjee, Jayashree Banerjee, Mohua Mazumdar, J. Phukan
Background: COVID-19 infection has been declared a pandemic in 2020 and since then it has been affecting the vast population of the world till today. Alteration of various hematological and biochemical parameters has been documented in various literatures. Aim: The aim of our study is to find out the prognostic role of hematological and biochemical parameters in severe and nonsevere COVID-19 patients. Materials and Methods: It was a retrospective record-based study conducted in a district-level COVID hospital of West Bengal, India. The COVID-confirmed patients admitted to the hospital during the second wave of COVID were included and data from records, including laboratory investigations were collected from the hospital registry. The severity of COVID was categorized based on the national guidelines. Independent samples t-test was applied to find out any relation of hematological and biochemical parameters abnormality in relation to disease severity. P < 0.05 was considered statistically significant. Results: A total of 94 COVID-confirmed cases were included in our study. Males constitute the majority of cases (51 males vs. 43 females). Seventeen cases were categorized as severe COVID (18.09%), whereas others were nonsevere COVID. Among hematological parameters, total leukocyte count (TLC), neutrophil and lymphocyte percentage, and neutrophil-to-lymphocyte ratio (NLR) were significantly altered among the severe compared to the nonsevere group (P < 0.05). While C-reactive protein (CRP), D-dimer, and serum ferritin levels also showed significant alteration among severe COVID patients (P < 0.05). Conclusion: Our study showed that severe COVID patients were significantly associated with neutrophilia, raised NLR, CRP, D-dimer, and serum ferritin levels.
{"title":"Impact of various hematological and biochemical parameters in severe and nonsevere COVID-19 patients: A retrospective single-center study","authors":"Aurobinda Banerjee, Jayashree Banerjee, Mohua Mazumdar, J. Phukan","doi":"10.4103/mj.mj_52_22","DOIUrl":"https://doi.org/10.4103/mj.mj_52_22","url":null,"abstract":"Background: COVID-19 infection has been declared a pandemic in 2020 and since then it has been affecting the vast population of the world till today. Alteration of various hematological and biochemical parameters has been documented in various literatures. Aim: The aim of our study is to find out the prognostic role of hematological and biochemical parameters in severe and nonsevere COVID-19 patients. Materials and Methods: It was a retrospective record-based study conducted in a district-level COVID hospital of West Bengal, India. The COVID-confirmed patients admitted to the hospital during the second wave of COVID were included and data from records, including laboratory investigations were collected from the hospital registry. The severity of COVID was categorized based on the national guidelines. Independent samples t-test was applied to find out any relation of hematological and biochemical parameters abnormality in relation to disease severity. P < 0.05 was considered statistically significant. Results: A total of 94 COVID-confirmed cases were included in our study. Males constitute the majority of cases (51 males vs. 43 females). Seventeen cases were categorized as severe COVID (18.09%), whereas others were nonsevere COVID. Among hematological parameters, total leukocyte count (TLC), neutrophil and lymphocyte percentage, and neutrophil-to-lymphocyte ratio (NLR) were significantly altered among the severe compared to the nonsevere group (P < 0.05). While C-reactive protein (CRP), D-dimer, and serum ferritin levels also showed significant alteration among severe COVID patients (P < 0.05). Conclusion: Our study showed that severe COVID patients were significantly associated with neutrophilia, raised NLR, CRP, D-dimer, and serum ferritin levels.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":"21 1","pages":"178 - 183"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44422258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Some Biomarkers in Diagnosis of Bacterial Bloodstream Infection in Children","authors":"M. Al-Mendalawi, M. Al-Khalidi","doi":"10.4103/mj.mj_42_21","DOIUrl":"https://doi.org/10.4103/mj.mj_42_21","url":null,"abstract":"","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":"21 1","pages":"202 - 202"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48198559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDAR) is a severe autoimmune disease caused by the development of immunoglobulin G antibodies against the NMDAR's GluN1 subunit in the cerebrospinal fluid. It is characterized by a wide range of clinical features including psychological manifestations, dyskinesia, and epileptic seizures. Intravenous methylprednisolone, intravenous immunoglobulin, and plasma exchange are the first-line treatments. Early diagnosis, treatment, monitoring, and follow-up of the disease are crucial as it results in favorable prognosis. In the pediatric age group, relapse is possible.
{"title":"Anti-N-Methyl-D-Aspartate receptor encephalitis in pediatrics: A review of clinical manifestations, treatment, and prognosis","authors":"Sawsan El Hussein, B. Ibrahim, W. Abdullah","doi":"10.4103/mj.mj_6_22","DOIUrl":"https://doi.org/10.4103/mj.mj_6_22","url":null,"abstract":"Anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDAR) is a severe autoimmune disease caused by the development of immunoglobulin G antibodies against the NMDAR's GluN1 subunit in the cerebrospinal fluid. It is characterized by a wide range of clinical features including psychological manifestations, dyskinesia, and epileptic seizures. Intravenous methylprednisolone, intravenous immunoglobulin, and plasma exchange are the first-line treatments. Early diagnosis, treatment, monitoring, and follow-up of the disease are crucial as it results in favorable prognosis. In the pediatric age group, relapse is possible.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":"21 1","pages":"96 - 99"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48592711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The recombinant human luteinizing hormone or human chorionic gonadotropin (hCG) has substantially taken over the product which was formulated from the urine of pregnant women. In addition to this, a number of randomized controlled trials have been conducted comparing the significance of recombinant hCG (rHCG) with urinary hCG in assisted reproduction. Nevertheless, the present study has collected secondary information based on the nature of the chosen research area. The acquired data and information have been analyzed using content analysis technique to review the methodology and findings of the selected research articles. With the use of rHCG as well as purified hCG, the serum level was equivalent at day 5 among women underwent intracytoplasmic sperm injection (ICSI) but this level abnormally increased among those injected with rHCG thus, minimizing the rate of pregnancy. It has been concluded that purified hCG trigger plays a more efficient role in inducing oocyte maturation and increasing the rate of pregnancy among women undergoing in vitro fertilization ICSI cycle in comparison to rHCG trigger.
{"title":"Recombinant human chorionic gonadotropin versus purified human chorionic gonadotropin trigger for In vitro Fertilization intracytoplasmic sperm injection cycle","authors":"Zeena R Helmi, Zainab Mussaid","doi":"10.4103/mj.mj_11_22","DOIUrl":"https://doi.org/10.4103/mj.mj_11_22","url":null,"abstract":"The recombinant human luteinizing hormone or human chorionic gonadotropin (hCG) has substantially taken over the product which was formulated from the urine of pregnant women. In addition to this, a number of randomized controlled trials have been conducted comparing the significance of recombinant hCG (rHCG) with urinary hCG in assisted reproduction. Nevertheless, the present study has collected secondary information based on the nature of the chosen research area. The acquired data and information have been analyzed using content analysis technique to review the methodology and findings of the selected research articles. With the use of rHCG as well as purified hCG, the serum level was equivalent at day 5 among women underwent intracytoplasmic sperm injection (ICSI) but this level abnormally increased among those injected with rHCG thus, minimizing the rate of pregnancy. It has been concluded that purified hCG trigger plays a more efficient role in inducing oocyte maturation and increasing the rate of pregnancy among women undergoing in vitro fertilization ICSI cycle in comparison to rHCG trigger.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":"21 1","pages":"111 - 113"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43243654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Mucoceles of paranasal sinuses are benign expansile mucus-filled cystic lesions due to chronic blockage of the sinus ostia. Due to their expansile growth, may affect nearby vital structures and lead to complications and morbidity. Objective: This study aims to evaluate the details of the clinical profile and management of paranasal sinus mucocele. Materials and Methods: This is a retrospective descriptive study of 54 patients with paranasal sinuses mucoceles that were managed with surgical interventions. Results: The age range of the study participants was between 12 years to 54 years. The mean age of the study patients was 28.61 years. Out of 54 patients, 34 (62.96%) were males and 20 (37.03%) females with a male-to-female ratio of 1.7:1. The frontal sinus (35.18%) was the most common sinus involved with mucocele followed by frontoethmoidal sinus (24.07%), ethmoid sinus, maxillary sinus (14.81%), and sphenoid sinus (9.25%). In this study, the headache was the most common symptom. Conclusion: Paranasal sinus mucocele has diverse clinical presentations. Allergic rhinitis, sinusitis, and radiation to the head-and-neck region are important predisposing factors for causing paranasal sinus mucocele. Orbital symptoms are indicators for prompt surgical intervention. Endoscopic sinus surgery is an effective and safe treatment option for paranasal sinus mucocele.
{"title":"Mucoceles of paranasal sinuses: Our experiences at a tertiary care teaching hospital of Eastern India","authors":"S. Swain, S. Panda","doi":"10.4103/mj.mj_12_22","DOIUrl":"https://doi.org/10.4103/mj.mj_12_22","url":null,"abstract":"Background: Mucoceles of paranasal sinuses are benign expansile mucus-filled cystic lesions due to chronic blockage of the sinus ostia. Due to their expansile growth, may affect nearby vital structures and lead to complications and morbidity. Objective: This study aims to evaluate the details of the clinical profile and management of paranasal sinus mucocele. Materials and Methods: This is a retrospective descriptive study of 54 patients with paranasal sinuses mucoceles that were managed with surgical interventions. Results: The age range of the study participants was between 12 years to 54 years. The mean age of the study patients was 28.61 years. Out of 54 patients, 34 (62.96%) were males and 20 (37.03%) females with a male-to-female ratio of 1.7:1. The frontal sinus (35.18%) was the most common sinus involved with mucocele followed by frontoethmoidal sinus (24.07%), ethmoid sinus, maxillary sinus (14.81%), and sphenoid sinus (9.25%). In this study, the headache was the most common symptom. Conclusion: Paranasal sinus mucocele has diverse clinical presentations. Allergic rhinitis, sinusitis, and radiation to the head-and-neck region are important predisposing factors for causing paranasal sinus mucocele. Orbital symptoms are indicators for prompt surgical intervention. Endoscopic sinus surgery is an effective and safe treatment option for paranasal sinus mucocele.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":"21 1","pages":"124 - 128"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45591937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Massive pleural effusion is one of the way of presentations of malignant effusion, it is unlikely to be seen in other causes of effusions, thorough workup and follow up is necessary, in this case series most of the cases was confirmed to be of malignant etiology. Objectives: The main objective from this study is to detect the cause behind massive pleural effusion and for early detection of a malignant etiology. Methods: Case series study involving 11 inpatient cases of massive effusion that had been evaluated sequentially with pleural fluid cytology then if negative pleural biopsy with either medical pleuroscopy or video assisted thoracoscopy (VATS). Results: Six of eleven cases were discovered to have malignant effusion, two cases were tuberculous pleuritis (TB pleuritis), one case were complicated parapneumonic effusion; the other 2 cases there were no specific diagnoses. Conclusions: Most of the cases of massive pleural effusion were discovered to be malignant effusion.
{"title":"Massive pleural effusion suggesting a malignant effusion: A case series study","authors":"M. Ibrahim","doi":"10.4103/mj.mj_44_22","DOIUrl":"https://doi.org/10.4103/mj.mj_44_22","url":null,"abstract":"Background: Massive pleural effusion is one of the way of presentations of malignant effusion, it is unlikely to be seen in other causes of effusions, thorough workup and follow up is necessary, in this case series most of the cases was confirmed to be of malignant etiology. Objectives: The main objective from this study is to detect the cause behind massive pleural effusion and for early detection of a malignant etiology. Methods: Case series study involving 11 inpatient cases of massive effusion that had been evaluated sequentially with pleural fluid cytology then if negative pleural biopsy with either medical pleuroscopy or video assisted thoracoscopy (VATS). Results: Six of eleven cases were discovered to have malignant effusion, two cases were tuberculous pleuritis (TB pleuritis), one case were complicated parapneumonic effusion; the other 2 cases there were no specific diagnoses. Conclusions: Most of the cases of massive pleural effusion were discovered to be malignant effusion.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":"21 1","pages":"189 - 191"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44657139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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