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MECHANISMS OF INFLUENCE OF UNBALANCED FEEDING ON MORPHO-FUNCTIONAL STATE OF LIVER IN PREGNANT RATS 不平衡摄食对妊娠大鼠肝脏形态功能状态的影响机制
Pub Date : 2021-01-01 DOI: 10.23856/4532
M. Kuznetsova, I. Kuznetsova
Summary Pathology of the organs of the hepatobiliary system is one of the leading causes of death in highly developed countries. Among various factors that can negatively affect the morphofunctional state of the liver in the mother-fetus system, the alimentary factor occupies the first place. The aim of this study was to establish the mechanisms of influence of excess nutrients in the diet on the morphology and functional state of the liver of pregnant rats. The structural and functional state of the liver of 7 rats that received an excess diet during pregnancy and 6 rats of the control group were studied. Morphological changes were manifested by uneven expression of eNOS and a positive reaction of iNOS, which was observed not only in macrophages, but also in single endothe-liocytes of dilated sinusoids. Functional changes were characterized by the development of dyslipidemia in the blood serum and the accumulation of TG and NEFA in the liver tissues. The data obtained in the course of the study may indicate pronounced disorders of lipid metabolism, which can be regarded as a risk factor for the development of steatosis, liver fibrosis, atherosclerosis and type 2 diabetes mellitus.
在高度发达的国家,肝胆系统器官的病理是导致死亡的主要原因之一。在对母胎系统中肝脏形态功能状态产生负面影响的各种因素中,饮食因素占据首位。本研究旨在探讨饲粮中过量营养物质对妊娠大鼠肝脏形态和功能的影响机制。研究了妊娠期过量饮食组7只大鼠和对照组6只大鼠肝脏的结构和功能状况。形态学变化表现为eNOS的不均匀表达和iNOS的阳性反应,不仅在巨噬细胞中可见,在扩张的窦状窦的单个内皮细胞中也可见。功能变化的特征是血清中出现血脂异常,肝组织中TG和NEFA的积累。在研究过程中获得的数据可能表明明显的脂质代谢紊乱,这可能是脂肪变性、肝纤维化、动脉粥样硬化和2型糖尿病发生的危险因素。
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引用次数: 0
THE CHANGING ATTITUDE TOWARDS STATE FRAGILITY 对国家脆弱性态度的转变
Pub Date : 2020-10-05 DOI: 10.23856/3840
D. Vilkova
The aim of the article is to trace the changes in the views of scholars on state fragility in recent decades. The paper marks the milestones of discourse changes on fragile states. The basic models and gaps in state functioning are covered, as well as the main aspects that have brought about changes in the attitude towards state fragility. The latest trends such as the usage of the resilient state term are also described. The article mentions the main poles of opinions towards the subject and mentions a range of existing debates in this regard. The greater context of international security is being taken into account. The view from the representatives of so-called fragile states is presented by the example of g7+ group. The article analyses the changes in the usage of the term, in the view of the core of the state functions and existing gaps as well as the latest trends in the discourse on state fragility.
本文的目的是追溯近几十年来学者对国家脆弱性观点的变化。本文标志着脆弱国家话语变迁的里程碑。涵盖了国家运作的基本模式和差距,以及导致人们对国家脆弱性态度发生变化的主要方面。本文还介绍了弹性状态术语的使用等最新趋势。文章提到了对这一主题的主要观点,并提到了在这方面存在的一系列争论。目前正在考虑到国际安全的更大范围。所谓脆弱国家代表的观点以g7+集团为例。本文从国家职能的核心、存在的差距以及国家脆弱性论述的最新趋势等方面分析了国家脆弱性一词的使用变化。
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引用次数: 0
THE PHENOMENON OF VIRTUAL COMMUNICATION UNDER THE CONDITIONS OF THE BECOMING AN INFORMATION SOCIETY 信息社会条件下的虚拟交流现象
Pub Date : 2020-10-05 DOI: 10.23856/3874
M. Palchynska
The article deals the virtual communication as one of the backbone elements of an information society. The large-scale spread of computer networks significantly transformed components such as communication processes, space, time and conceptual content. The formation an information society as a condition of multi-vector communication or polylogue, is constantly in the field of interaction and transitive provides the ability to design your own social identity. Particular attention is paid to the interactive aspects Virtual communication and transformation of communication patterns due to the lack of hard imperatives of social networking that contributes to the high variability of the personal self. Within the virtual space, produced a global computer network, develops specific language, a system of signs, symbols, symbols which set as their assimilation communicants ensures the effectiveness of the communication process. Virtual communication has become one of the factors of socio-cultural transformations of modern society, so an important tool for conceptual understanding of changes in the world is the analysis of the specifics of this aspect of social relations.
本文将虚拟通信作为信息社会的支柱要素之一。计算机网络的大规模传播极大地改变了通信过程、空间、时间和概念内容等组成部分。信息社会的形成是一种多媒介交流或多逻辑的条件,它不断地在互动和传递的领域中提供了设计自己的社会身份的能力。由于缺乏社交网络的硬性要求,导致个人自我的高度可变性,因此人们特别关注互动方面的虚拟沟通和沟通模式的转变。在虚拟空间中,产生了一个全球计算机网络,开发了特定的语言,一个由符号、符号、符号组成的系统,作为它们的同化传播者,确保了传播过程的有效性。虚拟交流已经成为现代社会社会社会文化变革的因素之一,因此从概念上理解世界变化的一个重要工具是分析社会关系这一方面的细节。
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引用次数: 0
CULTURAL FUNDAMENTALS OF THE CONTENT OF SCHOOL LITERARY EDUCATION: HISTORICAL AND PEDAGOGICAL DISCOURSE 学校文学教育内容的文化基础:历史与教学话语
Pub Date : 2020-01-01 DOI: 10.23856/4016
N. Hohol, Zoya Turyanytsya, Hameni Blaise
proposed by leading scientists on the basis of their dialogical interaction contribute to the deepening of knowledge of literary and art history, students' comprehension of a literary work as a unique text of culture, specifics, the formation of skills to analyze and interpret literary works in an artistic context. It is con-cluded that the theoretical and methodological guidelines of scientists of the late twentieth century on this issue have become the basis for constructive and critical understanding of the problem of cultural orientation of the content of school literary education in the early XXI century. others.Scientific investigations of Ukrainian and foreign scholars demonstrate both the diver-sity of certain aspects of this topic and the richness of modern approaches to its understanding, which are to justify the need to diversify methods and techniques, types and forms of work with the text of the work of art, development of methodological system introduction of innovative technologies of teaching Ukrainian and foreign literature etc.
由顶尖科学家提出的在他们对话互动的基础上有助于加深文学艺术史知识,使学生理解文学作品作为独特的文化文本,具体细节,形成在艺术语境中分析和解读文学作品的技能。文章认为,20世纪后期科学家在这一问题上的理论和方法指导,已成为对21世纪初学校文学教育内容的文化取向问题进行建设性和批判性理解的基础。别人。乌克兰和外国学者的科学调查表明,这一主题的某些方面的多样性和现代理解方法的丰富性,这证明需要多样化的方法和技术,艺术作品文本的工作类型和形式,方法系统的发展,引进乌克兰和外国文学教学的创新技术等。
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引用次数: 0
MARGINAL FEAR OF DESPAIR AS AN EXPLICATION OF THE INTEGRITY OF CONSCIOUSNESS (CREATIVE COMPONENT) 对绝望的边缘恐惧作为意识完整性的一种解释(创造性成分)
Pub Date : 2020-01-01 DOI: 10.23856/4115
S. Martynova, Valeru Melnik, Iwona Wojnowska
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引用次数: 0
RESEARCH OF PUBLIC ADMINISTRATION FOR INVESTMENT DEVELOPMENT OF REGIONS: THEORETICAL ASPECTS 区域投资发展公共管理研究:理论层面
Pub Date : 2020-01-01 DOI: 10.23856/4112
Oleksiy Buchynsky
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引用次数: 0
FORMING A MODERN SYSTEM OF MANAGING LAND RESOURCES OF TERRITORIAL COMMUNITIES IN THE CONDITIONS OF DECENTRALIZATION OF UKRAINE 在乌克兰分权的条件下,形成管理领土社区土地资源的现代制度
Pub Date : 2020-01-01 DOI: 10.23856/4114
Vitaliy Malookyy
Summary The article considers peculiarities of formatting modern system of land resources management for territorial communities under the conditions of decentralization in Ukraine. The author reasons that managing land resources of territorial communities today is an important scientific and applied problem at various levels of management. It is noted that today development of Ukraine is closely linked with the reform of its administrative-territorial structure, aimed at ensuring economic, social and financial capacity of each administrative unit – primarily the territorial community. The author emphasizes that in the context of ongoing decentralization reforms, mechanisms and processes that accompany functions and development of territorial communities are also being transformed. At the same time, certain extra powers are given to the united territorial communities, they become responsible for more effective management, including land and resource potential, which is the basis for the territory development. This is the reason to suggest development and implementation of interconnected system of legal, administrative and economic measures, at the level of local government, being united by the same goal of regulating land and property relations, to ensure stable, balanced and effective development of the territorial community.
摘要本文探讨了在乌克兰分权条件下建立现代领土社区土地资源管理制度的特点。本文认为,国土社区土地资源管理是当前各级管理中一个重要的科学问题和应用问题。人们注意到,乌克兰今天的发展同其行政-领土结构的改革密切相关,改革的目的是确保每个行政单位- -主要是领土共同体- -的经济、社会和财政能力。发件人强调,在正在进行的权力下放改革的背景下,与领土社区的职能和发展相伴随的机制和进程也正在改变。同时,给予联合领土社区一些额外的权力,它们负责更有效的管理,包括土地和资源潜力,这是领土发展的基础。这就是建议在地方政府一级制定和实施法律、行政和经济措施相互联系的制度的原因,这些措施是为了调节土地和财产关系的同一目标而统一的,以确保领土社区的稳定、平衡和有效发展。
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引用次数: 0
INTERNET PLUS STRATEGY AS A FACTOR OF DEVELOPMENT OF ECONOMIC EDUCATION IN THE PEOPLE’S REPUBLIC OF CHINA 互联网+战略作为中华人民共和国经济教育发展的一个因素
Pub Date : 2020-01-01 DOI: 10.23856/3879
K. Tsytsiura, Wanquan Gao
The development of the Internet greatly influences the transformation and modernization of the industries and businesses in the People’s Republic of China. As a result, the Chinese government has developed a special Internet Plus strategy to transform, modernize and equip conventional industries for joining the modern economy. This strategy is being implemented through the development of mobile devices, cloud services and new generation applications connecting people to social media, analytics and big data. Such development is going to attract foreign businesses planning to make an impact on the booming Chinese Internet economy, with the growing need for the experienced economists to assist their efforts. The specific characteristics and the areas of application of Internet Plus in different industries have been summed up and characterized. The ways of application of Internet Plus in economic education of the People’s Republic of China were substantiated. The effective mobile applications used for educational purposes with the economists in the higher educational institutions of the People’s Republic of China were highlighted and analyzed. The recommendations to be applied in foreign economic education using the benefits of Internet Plus strategy were formulated.Understanding and application of the Internet Plus strategy is a critical component for the economists in People’s Republic of China and abroad to achieve career success and open future businesses to enter the Chinese and world market.
互联网的发展极大地影响着中华人民共和国工业和商业的转型和现代化。因此,中国政府制定了专门的“互联网+”战略,以改造、现代化和装备传统产业,以融入现代经济。这一战略正在通过开发移动设备、云服务和新一代应用程序来实施,这些应用程序将人们与社交媒体、分析和大数据联系起来。这样的发展将吸引计划对蓬勃发展的中国互联网经济产生影响的外国企业,越来越需要经验丰富的经济学家来协助他们的努力。总结了“互联网+”在不同行业的具体特点和应用领域。实证了“互联网+”在我国经济教育中的应用途径。强调并分析了中华人民共和国高等教育机构中经济学家用于教育目的的有效移动应用程序。提出了利用“互联网+”战略优势开展对外经济教育的建议。理解和应用“互联网+”战略是中国和海外经济学家取得事业成功和打开未来业务进入中国和世界市场的关键组成部分。
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引用次数: 3
FORMATION METHODICAL COMPONENT OF PROFESSIONAL COMPETENCE OF STUDENTS SPECIALTY “SECONDARY EDUCATION” (MATHEMATICS AND PHYSIСS) BY DIGITAL TOOLS 通过数字工具形成学生专业“中等教育”(数学和physiСs)专业能力的系统组成部分
Pub Date : 2020-01-01 DOI: 10.23856/3922
Oksana Garpul, H. Voitkiv, Mirosława Skalik
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引用次数: 0
THE REPRESENTATION OF THE FEMALE PROTAGONIST IN JOANNE HARRIS’S NOVEL “GENTLEMEN AND PLAYERS” 乔安妮·哈里斯小说《绅士与花花公子》中女性主人公的形象表现
Pub Date : 2020-01-01 DOI: 10.23856/3904
Antonina Bulyna
The paper zeroes in on the peculiarities of representing the main female character in a British novel “Gentlemen and Players” published in 2005. The crucial point that the research encompasses is a challenge to the status quo of gender imbalance which is portrayed, inter alia, through showing a certain playfulness of the main character. Notably, playfulness must be read here as a form of (social/cultural/political) subversion, which enables one to look beyond and deconstruct “arbitrary ranks/truths”. The carnivalesque nature of the female protagonist is manifested in connection with the changing status of women in contemporary societies. The image of a submissive woman fabricated by men still lingers in many cultures. This gives rise to a mutant woman, mirrored with the help of a subversive fictional female character who is a trickster. It is evinced that the fossilized patterns of perceiving a woman, and attitudes towards her in the male-dominated environment are likely to pose an impending threat, not only to men’s lives but also to the lives of children and other women. Affected by a number of factors, the female protagonist reveals her eclectic identity and we witness how she turns into a monstrous creature with overwhelming destructive power inside. Consequently, the authenticity of the woman suffers and we may talk about her symbolic death.
这篇论文聚焦于2005年出版的英国小说《绅士与花花公子》中扮演主要女性角色的特点。该研究的关键点是对性别失衡现状的挑战,这一挑战主要通过表现主角的某种顽皮来描绘。值得注意的是,玩乐在这里必须被理解为(社会/文化/政治)颠覆的一种形式,它使人们能够超越并解构“武断的等级/真理”。女主人公的狂欢性表现与当代社会中女性地位的变化有关。在许多文化中,男性塑造的顺从的女性形象仍然存在。这就产生了一个变异的女人,在一个颠覆性的虚构女性角色的帮助下,她是一个骗子。显然,在男性主导的环境中,对女性的刻板印象和对女性的态度不仅可能对男性的生命,而且可能对儿童和其他女性的生命构成迫在眉睫的威胁。在一系列因素的影响下,女主人公揭示了她的折衷身份,我们见证了她是如何变成一个拥有强大破坏力的怪物的。因此,这个女人的真实性受到了损害,我们可以谈论她象征性的死亡。
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引用次数: 0
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Periodyk Naukowy Akademii Polonijnej
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