Pub Date : 2023-05-25DOI: 10.32539/jkk.v10i2.21362
N. Putri, Martha Mozartha, S. W. Rais
{"title":"DAYA HAMBAT EKSTRAK GYNURA PSEUDOCHINA TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS PADA PLAT AKRILIK POLIMERISASI PANAS","authors":"N. Putri, Martha Mozartha, S. W. Rais","doi":"10.32539/jkk.v10i2.21362","DOIUrl":"https://doi.org/10.32539/jkk.v10i2.21362","url":null,"abstract":"","PeriodicalId":34033,"journal":{"name":"Jurnal Kedokteran dan Kesehatan","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89781489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Relation between Clinical Symptoms and the Location of Adhesive Lesion in Endometriosis Patients. Endometriosis is a chronic condition in which functional endometrial tissue implants outside the uterine cavity. The diagnosis of endometriosis is quite difficult and often goes undetected for a long time, so this study aims to help make the diagnosis faster because it can estimate the location of the lesion earlier. This research is an analytic observational type with a cross-sectional approach and the sample are 102 patients. The most common location of adhesions was in the uterus in 54 patients (52.9%) and the most clinical symptom was dysmenorrhea in 71 patients (69.6%). The relationship of dysmenorrhea symptoms with the location of adhesions in the uterus obtained a p-value of 0.732 and the relationship of dyspareunia symptoms with the location of adhesions in the cul de sac obtained a p-value of 0.525. While research on the relationship between clinical symptoms of dyschezia and location in the rectum produced a p value of 0.031 and a PR value of 10.90 (95% CI 1.19 – 99.78). There was no significant relationship between the clinical symptoms of dysmenorrhea and the location of the adhesions in the uterus and the relationship between the clinical symptoms of dyspareunia and the location of the adhesions in the cul de sac. However, there is a relationship between the clinical symptoms of dyschezia and the location of the adhesions in the rectum.
子宫内膜异位症粘连病灶部位与临床症状的关系。子宫内膜异位症是一种慢性疾病，其中功能子宫内膜组织植入子宫腔外。子宫内膜异位症的诊断相当困难，往往长时间未被发现，因此本研究旨在帮助更快的诊断，因为它可以更早地估计病变的位置。本研究为横断面分析观察型，样本为102例患者。粘连最常见于子宫54例(52.9%)，临床症状以痛经71例(69.6%)。痛经症状与子宫粘连位置的关系p值为0.732，性交困难症状与子宫囊尾粘连位置的关系p值为0.525。而对精神障碍临床症状与直肠部位关系的研究，p值为0.031,PR值为10.90 (95% CI 1.19 ~ 99.78)。痛经的临床症状与子宫粘连部位、性交困难的临床症状与子宫囊尾粘连部位的关系均不显著。然而，精神障碍的临床症状与直肠粘连的位置有一定的关系。
{"title":"HUBUNGAN ANTARA GEJALA KLINIS DAN LOKASI PERLENGKETAN LESI PADA PENDERITA ENDOMETRIOSIS","authors":"Qherine Bhelqis, H. Hartati, Fatmawati Fatmawati, Firmansyah Seta Basyir, Rara Inggarsih","doi":"10.32539/jkk.v10i2.19953","DOIUrl":"https://doi.org/10.32539/jkk.v10i2.19953","url":null,"abstract":"The Relation between Clinical Symptoms and the Location of Adhesive Lesion in Endometriosis Patients. Endometriosis is a chronic condition in which functional endometrial tissue implants outside the uterine cavity. The diagnosis of endometriosis is quite difficult and often goes undetected for a long time, so this study aims to help make the diagnosis faster because it can estimate the location of the lesion earlier. This research is an analytic observational type with a cross-sectional approach and the sample are 102 patients. The most common location of adhesions was in the uterus in 54 patients (52.9%) and the most clinical symptom was dysmenorrhea in 71 patients (69.6%). The relationship of dysmenorrhea symptoms with the location of adhesions in the uterus obtained a p-value of 0.732 and the relationship of dyspareunia symptoms with the location of adhesions in the cul de sac obtained a p-value of 0.525. While research on the relationship between clinical symptoms of dyschezia and location in the rectum produced a p value of 0.031 and a PR value of 10.90 (95% CI 1.19 – 99.78). There was no significant relationship between the clinical symptoms of dysmenorrhea and the location of the adhesions in the uterus and the relationship between the clinical symptoms of dyspareunia and the location of the adhesions in the cul de sac. However, there is a relationship between the clinical symptoms of dyschezia and the location of the adhesions in the rectum.","PeriodicalId":34033,"journal":{"name":"Jurnal Kedokteran dan Kesehatan","volume":"50 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90995658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-25DOI: 10.32539/jkk.v10i1.21350
Y. Magdi, Guntur Bayu Bima Pratama, E. Bahar
Smell is a chemical substance mixed in the air that humans perceive with their sense of smell. Loss of smell or loss of smell has become very important in recent years. Currently, research on odor is very interesting because it can determine the type of odor, as well as the function of smell. Examination of the intravenous smell test and alcohol smell test is one of the gold standard examinations that can be done to determine the type of smell disorder. To determine the concordance between the results of the intravenous alinamin smell test and the alcohol smell test in patients with olfactory disorders at RSMH Palembang. Observational and analytic research using cross sectional. Data collection was carried out using the medical records of RSUP Dr. Mohammad Hoesin Palembang for the period October 2022 to January 2023. Data were analyzed with IBM SPSS 25. In this study, there were 49 patients with complaints of smell disturbances to the THTBKL department of RSUP Dr. Mohammad Hoesin Palembang. The mean age in the study was 33 years old with the most vulnerable population aged <20 years (26.5%). With the majority of the female sex (57.1%). While the majority of the work is mostly students (26.5%) and complains of gradual disturbance smells (91.8%). Most of the patients who came with complaints of smell disturbances were patients with sinonasal masses (53.1%). The correlation between intravenous alinamin and alcohol smell tests using the Spearman correlation test showed a very strong correlation (r=0.908) and in the conformity test using Cohen's kappa value obtained was 1.000 which means that perfect agreement was reached between the two tests. There is a concordance in the examination results between the alinamin smell test and the alcohol smell test in patients with complaints of smell disorders.
气味是一种混合在空气中的化学物质，人类用嗅觉感知。近年来，嗅觉丧失变得非常重要。目前，对气味的研究非常有趣，因为它可以确定气味的类型，以及气味的功能。静脉嗅觉测试和酒精嗅觉测试是确定嗅觉障碍类型的金标准检查之一。确定巨港RSMH嗅觉障碍患者静脉丙胺素嗅觉试验结果与酒精嗅觉试验结果的一致性。使用横断面进行观察和分析研究。利用RSUP Mohammad Hoesin Palembang医生2022年10月至2023年1月期间的医疗记录进行了数据收集。数据采用IBM SPSS 25进行分析。在这项研究中，有49名患者向RSUP Mohammad Hoesin Palembang医生的THTBKL部门投诉嗅觉障碍。研究的平均年龄为33岁，最脆弱人群年龄<20岁(26.5%)。以女性居多(57.1%)。而投诉的主体主要是学生(26.5%)和逐渐滋扰的气味(91.8%)。以嗅觉障碍为主诉的患者多为鼻窦肿块患者(53.1%)。使用Spearman相关检验的静脉丙氨酸胺和酒精气味测试之间的相关性显示出很强的相关性(r=0.908)，使用Cohen的kappa值获得的一致性检验为1.000，这意味着两个测试之间达到了完全一致。在嗅觉障碍主诉患者中，丙胺素嗅觉试验与酒精嗅觉试验的检查结果具有一致性。
{"title":"RESULTS OF INTRAVENOUS ALINAMIN AND ALCOHOL EXAMINATION RESULTS IN PATIENTS COMPLAINTS OF SNACTING DISORDERS AT RSMH PALEMBANG","authors":"Y. Magdi, Guntur Bayu Bima Pratama, E. Bahar","doi":"10.32539/jkk.v10i1.21350","DOIUrl":"https://doi.org/10.32539/jkk.v10i1.21350","url":null,"abstract":"Smell is a chemical substance mixed in the air that humans perceive with their sense of smell. Loss of smell or loss of smell has become very important in recent years. Currently, research on odor is very interesting because it can determine the type of odor, as well as the function of smell. Examination of the intravenous smell test and alcohol smell test is one of the gold standard examinations that can be done to determine the type of smell disorder. To determine the concordance between the results of the intravenous alinamin smell test and the alcohol smell test in patients with olfactory disorders at RSMH Palembang. Observational and analytic research using cross sectional. Data collection was carried out using the medical records of RSUP Dr. Mohammad Hoesin Palembang for the period October 2022 to January 2023. Data were analyzed with IBM SPSS 25. In this study, there were 49 patients with complaints of smell disturbances to the THTBKL department of RSUP Dr. Mohammad Hoesin Palembang. The mean age in the study was 33 years old with the most vulnerable population aged <20 years (26.5%). With the majority of the female sex (57.1%). While the majority of the work is mostly students (26.5%) and complains of gradual disturbance smells (91.8%). Most of the patients who came with complaints of smell disturbances were patients with sinonasal masses (53.1%). The correlation between intravenous alinamin and alcohol smell tests using the Spearman correlation test showed a very strong correlation (r=0.908) and in the conformity test using Cohen's kappa value obtained was 1.000 which means that perfect agreement was reached between the two tests. There is a concordance in the examination results between the alinamin smell test and the alcohol smell test in patients with complaints of smell disorders.","PeriodicalId":34033,"journal":{"name":"Jurnal Kedokteran dan Kesehatan","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83651044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-25DOI: 10.32539/jkk.v10i2.20275
Yuliati Natalia, Ghea De Silva, Wa Djatmiko
{"title":"HUBUNGAN ANTARA RASIO NEUTROFIL LIMFOSIT DENGAN DERAJAT KEPARAHAN COVID-19 PADA PASIEN DI RSUD PROF. DR. MARGONO SOEKARJO","authors":"Yuliati Natalia, Ghea De Silva, Wa Djatmiko","doi":"10.32539/jkk.v10i2.20275","DOIUrl":"https://doi.org/10.32539/jkk.v10i2.20275","url":null,"abstract":"","PeriodicalId":34033,"journal":{"name":"Jurnal Kedokteran dan Kesehatan","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85347749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The most consumed and cultivated coffee in Indonesia is robusta and arabica coffee. Robusta and arabica coffee have different characteristics such as morphology, contents, and taste. Coffee consumption could cause alteration in taste sensitivity, especially sweet taste. Those could affect daily sugar consumption. The present study aimed to determine the differences of short-term consumption of semendo robusta and arabica coffee towards sweet taste sensitivity. This study used experimental study with a cross-over design approach that involved 21 students from the Faculty of Medicine Sriwijaya University. Semendo robusta and arabica coffee are used in this study. Sweet taste sensitivity was tested using the whole mouth test method by rinsed with sucrose solution at a concentration of 0,16, 0,32, 0,64, and 1,28 mol/l, which was given from the lowest concentration. Sweet taste sensitivity scores were rated at baseline and after the consumption of semendo robusta and arabica coffee which took place on different days. The lowest sucrose concentration that was correctly interpreted by the subject was noted as a taste sensitivity score. Data were analyzed using the Chi-square test. The chi-square test showed that the decrease in sweet taste sensitivity was more frequently happening after semendo arabica coffee consumption than semendo robusta coffee consumption (p<0,05). Short-term consumption of semendo arabica coffee has significantly increased the risk of sweet taste sensitivity reduction 4 times greater than semendo robusta coffee. There were differences in sweet taste sensitivity between short-term consumption of semendo robusta and arabica coffee.
{"title":"DIFFERENCES OF SHORT-TERM CONSUMPTION OF SEMENDO ROBUSTA AND ARABICA COFFEE TOWARDS SWEET TASTE SENSITIVITY","authors":"Pudi Handayani, Irfannuddin Irfannuddin, Alifia Salsabila, Shanty Chairani, Nursiah Nasution","doi":"10.32539/jkk.v10i2.20924","DOIUrl":"https://doi.org/10.32539/jkk.v10i2.20924","url":null,"abstract":"The most consumed and cultivated coffee in Indonesia is robusta and arabica coffee. Robusta and arabica coffee have different characteristics such as morphology, contents, and taste. Coffee consumption could cause alteration in taste sensitivity, especially sweet taste. Those could affect daily sugar consumption. The present study aimed to determine the differences of short-term consumption of semendo robusta and arabica coffee towards sweet taste sensitivity. This study used experimental study with a cross-over design approach that involved 21 students from the Faculty of Medicine Sriwijaya University. Semendo robusta and arabica coffee are used in this study. Sweet taste sensitivity was tested using the whole mouth test method by rinsed with sucrose solution at a concentration of 0,16, 0,32, 0,64, and 1,28 mol/l, which was given from the lowest concentration. Sweet taste sensitivity scores were rated at baseline and after the consumption of semendo robusta and arabica coffee which took place on different days. The lowest sucrose concentration that was correctly interpreted by the subject was noted as a taste sensitivity score. Data were analyzed using the Chi-square test. The chi-square test showed that the decrease in sweet taste sensitivity was more frequently happening after semendo arabica coffee consumption than semendo robusta coffee consumption (p<0,05). Short-term consumption of semendo arabica coffee has significantly increased the risk of sweet taste sensitivity reduction 4 times greater than semendo robusta coffee. There were differences in sweet taste sensitivity between short-term consumption of semendo robusta and arabica coffee.","PeriodicalId":34033,"journal":{"name":"Jurnal Kedokteran dan Kesehatan","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79919087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-25DOI: 10.32539/jkk.v10i2.21252
Msy Rulan Adnindya, Indri Seta Septadina, T. Suciati, Wardiansah Wardiansah
The mandibular nerve is the largest branch of the trigeminal nerve. It innervates the mandibular teeth, gums, skin of the temporal region, ear, lower lip, the lower part of the face, muscles of mastication, and mucous membrane of the anterior 2/3 of the tongue. The mandibular nerve is the main pharyngeal nerve arch. The sensory and motor fibers in the mandibular nerve originate from two roots: the sensory root, which originates from the semilunar ganglion, and the motor root, which originates from the motor nucleus. The mandibular nerve has a mixture of sensory and motor nerves and motor and sensory functions. Face, cheeks and temples, oral cavity, teeth and gums, nasal cavity and sinuses, and temporomandibular joints and muscles. Trauma to the mandible can damage or tear the inferior alveolar nerve in the mandibular canal, causing sensory loss distal to the lesion. Local anesthesia of the inferior alveolar nerve is generally reserved for dental procedures. Local anesthetic injection into the oral mucosa on the medial side of the mandible can also involve the nearby lingual nerve, thus affecting the tongue and the inside of the mouth. The close connection between the submandibular canal and the lingual nerve is important in root canal infections and surgical procedures.
{"title":"FUNCTIONAL ANATOMY OF MANDIBULAR NERVE","authors":"Msy Rulan Adnindya, Indri Seta Septadina, T. Suciati, Wardiansah Wardiansah","doi":"10.32539/jkk.v10i2.21252","DOIUrl":"https://doi.org/10.32539/jkk.v10i2.21252","url":null,"abstract":"The mandibular nerve is the largest branch of the trigeminal nerve. It innervates the mandibular teeth, gums, skin of the temporal region, ear, lower lip, the lower part of the face, muscles of mastication, and mucous membrane of the anterior 2/3 of the tongue. The mandibular nerve is the main pharyngeal nerve arch. The sensory and motor fibers in the mandibular nerve originate from two roots: the sensory root, which originates from the semilunar ganglion, and the motor root, which originates from the motor nucleus. The mandibular nerve has a mixture of sensory and motor nerves and motor and sensory functions. Face, cheeks and temples, oral cavity, teeth and gums, nasal cavity and sinuses, and temporomandibular joints and muscles. Trauma to the mandible can damage or tear the inferior alveolar nerve in the mandibular canal, causing sensory loss distal to the lesion. Local anesthesia of the inferior alveolar nerve is generally reserved for dental procedures. Local anesthetic injection into the oral mucosa on the medial side of the mandible can also involve the nearby lingual nerve, thus affecting the tongue and the inside of the mouth. The close connection between the submandibular canal and the lingual nerve is important in root canal infections and surgical procedures.","PeriodicalId":34033,"journal":{"name":"Jurnal Kedokteran dan Kesehatan","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79357187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-25DOI: 10.32539/jkk.v10i2.20879
Muhammad Taufiq Al Hakim, Hendra Sutysna
Musculoskeletal Disorders (MSDs) atau Gangguan Muskuloskeletal merupakan masalah yang terjadi terutama pada bagian otot dan sendi yang dapat mengganggu aktivitas sehari-hari. Salah satu pilihan terapi pada keluhan MSDs yang saat ini berkembang adalah Terapi Bekam. Penelitian ini bertujuan untuk mengetahui pengaruh dari terapi bekam terhadap keluhan artikular kronik pada pasien penderita MSDs. Penelitian ini menggunakan jenis kuasi eksperimen dengan rancangan pre-test post-test without control group design. Jumlah subjek penelitian adalah 22 orang. Analisis data menggunakan uji T-berpasangan atau uji Wilcoxon sign rank dan uji McNemar. Hasil uji memperlihatkan bahwa terdapat pengaruh yang signifikan pada skala nyeri (p<0,001). Pada domain kualitas hidup fungsi fisik (p=0,003), nyeri (p=0,019), dan kesehatan umum (p=0,001) yang menunjukkan perubahan yang bermakna. Pada variabel batasan lingkup gerak sendi (p<0,001) dan kaku sendi (p=0,016) juga menunjukkan perubahan yang bermakna. Kesimpulan penelitian ini adalah terapi bekam basah memiliki pengaruh yang signifikan terhadap perubahan skala nyeri, Batasan lingkup gerak sendi, kaku sendi, namun tidak pada kualitas hidup secara keseluruhan.
{"title":"PENGARUH TERAPI BEKAM BASAH (AL-HIJAMAH) TERHADAP KELUHAN ARTIKULAR PADA PASIEN MUSCULOSKELETAL DISORDERS DI KLINIK BEKAM KOTA MEDAN","authors":"Muhammad Taufiq Al Hakim, Hendra Sutysna","doi":"10.32539/jkk.v10i2.20879","DOIUrl":"https://doi.org/10.32539/jkk.v10i2.20879","url":null,"abstract":"Musculoskeletal Disorders (MSDs) atau Gangguan Muskuloskeletal merupakan masalah yang terjadi terutama pada bagian otot dan sendi yang dapat mengganggu aktivitas sehari-hari. Salah satu pilihan terapi pada keluhan MSDs yang saat ini berkembang adalah Terapi Bekam. Penelitian ini bertujuan untuk mengetahui pengaruh dari terapi bekam terhadap keluhan artikular kronik pada pasien penderita MSDs. Penelitian ini menggunakan jenis kuasi eksperimen dengan rancangan pre-test post-test without control group design. Jumlah subjek penelitian adalah 22 orang. Analisis data menggunakan uji T-berpasangan atau uji Wilcoxon sign rank dan uji McNemar. Hasil uji memperlihatkan bahwa terdapat pengaruh yang signifikan pada skala nyeri (p<0,001). Pada domain kualitas hidup fungsi fisik (p=0,003), nyeri (p=0,019), dan kesehatan umum (p=0,001) yang menunjukkan perubahan yang bermakna. Pada variabel batasan lingkup gerak sendi (p<0,001) dan kaku sendi (p=0,016) juga menunjukkan perubahan yang bermakna. Kesimpulan penelitian ini adalah terapi bekam basah memiliki pengaruh yang signifikan terhadap perubahan skala nyeri, Batasan lingkup gerak sendi, kaku sendi, namun tidak pada kualitas hidup secara keseluruhan.","PeriodicalId":34033,"journal":{"name":"Jurnal Kedokteran dan Kesehatan","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73169739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"GAMBARAN KEAMANAN KANDUNGAN ASAM BENZOAT PADA MANISAN BUAH KEDONDONG YANG DIJUAL DI KAWASAN WISATA MUSEUM TSUNAMI BANDA ACEH","authors":"Elfariyanti Elfariyanti, Irma Zarwinda, Zunaili Rihadhatul Aisy, Dwi Putri Rejeki","doi":"10.32539/jkk.v10i2.20761","DOIUrl":"https://doi.org/10.32539/jkk.v10i2.20761","url":null,"abstract":"","PeriodicalId":34033,"journal":{"name":"Jurnal Kedokteran dan Kesehatan","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77918934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-25DOI: 10.32539/jkk.v10i2.19864
Eny Nurhikma, Randa Wulaisfan, Musdalipah Musdalipah, Y. Fauziah, Nirwati Rusli
Masker gel peel
面膜凝胶皮
{"title":"FORMULASI SEDIAAN MASKER GEL PEEL OFF EKSTRAK DAUN WALAY (MEISTERA CHINENSIS) ASAL SULAWESI TENGGARA","authors":"Eny Nurhikma, Randa Wulaisfan, Musdalipah Musdalipah, Y. Fauziah, Nirwati Rusli","doi":"10.32539/jkk.v10i2.19864","DOIUrl":"https://doi.org/10.32539/jkk.v10i2.19864","url":null,"abstract":"Masker gel peel","PeriodicalId":34033,"journal":{"name":"Jurnal Kedokteran dan Kesehatan","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75565853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health Care Workers (HCWs) are a top priority to receive the vaccination for Coronavirus Disease 2019 (Covid-19). After two doses of the Sinovac vaccine as the primary vaccine, protection against Covid-19 weakens over time, so a booster vaccination is considered to produce more antibodies. In addition, each vaccine is inseparable from Adverse Event Following Immunization (AEFI). This study compares antibody levels and AEFIs between two doses of the Sinovac vaccine with the Moderna booster. This research is an observational analytic study with a cross-sectional study design and the sampling method is random sampling with a total of 74 HCWs using a consecutive sampling method. Samples that had received two doses of the Sinovac vaccine or booster doses of the Moderna vaccine after two doses of the Sinovac vaccine were included. Samples that had been infected with Covid-19 before vaccination were excluded. IgG antibody levels were measured using Chemiluminescent Microparticle Immunoassay (CMIA), while vaccine type and AEFI were gathered via questionnaire. The severity of AEFIs is based on WHO classification. The data analysis used the Mann-Whitney and Chi-Square tests with a 95% Confidence Interval (CI) to determine the relationship between variables. Twenty-nine subjects received two doses of the Sinovac primary vaccine (38.2%), and forty-five received the Moderna booster vaccine (59.2%). In booster doses of the Moderna vaccine recipients, antibodies tended to be higher, and the most common AEFIs were systemic. There was a significant difference in IgG antibody levels between recipients of two doses of the Sinovac vaccine (median=2888.8 AU/mL) and booster Moderna vaccine recipients (median=18081.04 AU/mL) (p=0.000, p <0.05). There were significant differences in AEFI in the groups receiving two doses of the Sinovac vaccine and those receiving the booster vaccine (p=0.000, p<0.05). This study concludes that there is a significant correlation between administering the Covid-19 vaccine and post-vaccination IgG antibody levels and AEFI.
卫生保健工作者(HCWs)是接种2019冠状病毒病(Covid-19)疫苗的重中之重。在接种了两剂科兴疫苗作为主疫苗后，对Covid-19的保护作用会随着时间的推移而减弱，因此人们认为加强疫苗可以产生更多的抗体。此外，每种疫苗都离不开免疫后不良事件(AEFI)。本研究比较了两剂科兴疫苗和Moderna加强剂之间的抗体水平和aefi。本研究为观察性分析性研究，采用横断面研究设计，抽样方法为随机抽样，采用连续抽样方法，共74例HCWs。包括接受了两剂科兴疫苗或在两剂科兴疫苗后接受了Moderna疫苗加强剂的样本。排除接种疫苗前已感染Covid-19的样本。采用化学发光微粒免疫分析法(CMIA)检测IgG抗体水平，通过问卷调查收集疫苗类型和AEFI。急性呼吸道感染的严重程度是根据世卫组织的分类确定的。数据分析采用95%置信区间(CI)的Mann-Whitney检验和卡方检验来确定变量之间的关系。29名受试者接种了两剂科兴一疫苗(38.2%)，45名受试者接种了Moderna加强疫苗(59.2%)。在现代疫苗的加强剂量接受者中，抗体往往更高，并且最常见的aefi是全身性的。两剂新科疫苗接种者IgG抗体水平(中位数=2888.8 AU/mL)与现代加强疫苗接种者(中位数=18081.04 AU/mL)差异有统计学意义(p=0.000, p <0.05)。两剂科兴疫苗接种组与加强疫苗接种组AEFI差异有统计学意义(p=0.000, p<0.05)。本研究得出结论，接种新冠病毒疫苗与接种后IgG抗体水平和AEFI存在显著相关性。
{"title":"ANTIBODY IgG LEVELS AND ADVERSE EVENTS FOLLOWING IMMUNIZATION AFTER THIRD DOSE OF MODERNA VACCINE IN HEALTHWORKERS AFTER TWO DOSES OF SINOVAC VACCINE","authors":"Ade Tiur Rumondang, Utari Hartati Suryani, Debie Rizqoh, M. Sariyanti, Besly Sinuhaji","doi":"10.32539/jkk.v10i2.20872","DOIUrl":"https://doi.org/10.32539/jkk.v10i2.20872","url":null,"abstract":"Health Care Workers (HCWs) are a top priority to receive the vaccination for Coronavirus Disease 2019 (Covid-19). After two doses of the Sinovac vaccine as the primary vaccine, protection against Covid-19 weakens over time, so a booster vaccination is considered to produce more antibodies. In addition, each vaccine is inseparable from Adverse Event Following Immunization (AEFI). This study compares antibody levels and AEFIs between two doses of the Sinovac vaccine with the Moderna booster. This research is an observational analytic study with a cross-sectional study design and the sampling method is random sampling with a total of 74 HCWs using a consecutive sampling method. Samples that had received two doses of the Sinovac vaccine or booster doses of the Moderna vaccine after two doses of the Sinovac vaccine were included. Samples that had been infected with Covid-19 before vaccination were excluded. IgG antibody levels were measured using Chemiluminescent Microparticle Immunoassay (CMIA), while vaccine type and AEFI were gathered via questionnaire. The severity of AEFIs is based on WHO classification. The data analysis used the Mann-Whitney and Chi-Square tests with a 95% Confidence Interval (CI) to determine the relationship between variables. Twenty-nine subjects received two doses of the Sinovac primary vaccine (38.2%), and forty-five received the Moderna booster vaccine (59.2%). In booster doses of the Moderna vaccine recipients, antibodies tended to be higher, and the most common AEFIs were systemic. There was a significant difference in IgG antibody levels between recipients of two doses of the Sinovac vaccine (median=2888.8 AU/mL) and booster Moderna vaccine recipients (median=18081.04 AU/mL) (p=0.000, p <0.05). There were significant differences in AEFI in the groups receiving two doses of the Sinovac vaccine and those receiving the booster vaccine (p=0.000, p<0.05). This study concludes that there is a significant correlation between administering the Covid-19 vaccine and post-vaccination IgG antibody levels and AEFI.","PeriodicalId":34033,"journal":{"name":"Jurnal Kedokteran dan Kesehatan","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89546346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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