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Integrating chemical, organic, water-soluble and microbial fertilizers achieve mutually benefits of high nutrient utilization, improved yield and quality in tobacco cultivation 化学肥料、有机肥料、水溶性肥料和微生物肥料相结合,在烟草种植中实现了养分利用率高、产量和品质提高的互利共赢
IF 6.2 Q1 AGRICULTURE, MULTIDISCIPLINARY Pub Date : 2026-03-01 Epub Date: 2026-01-10 DOI: 10.1016/j.jafr.2026.102667
Wei Yang , Chenjian Zhao , Zhijie Chen , Xiaopeng Deng , Junying Li , Junwei Sun , Panlei Wang , Bo Zhu , Bingxue Wang , Zhengqin Xiong , Yu'e Li , Bin Wang
Optimizing nutrient management measures is fundamental to balancing tobacco yield and quality. While individual effects of fertilizers are well-documented, the integrated synergy of organic amendments with water-soluble fertilizers or microbial agents remains relatively scarce. Hence, a two-year field experiment was conducted to evaluate the comprehensive effects of five distinct nutrient management measures, no fertilization (CK), conventional chemical fertilizer (CF), organic fertilizer combined with conventional chemical fertilizer (CM), organic fertilizer combined with water-soluble fertilizer (WS), organic fertilizer combined with a compound microbial agent (OM), on tobacco growth, nutrient uptake and its use efficiency, leaf chemical composition, yield, quality, and revenue. The results revealed that WS and OM treatments increased tobacco yield and quality (proportion of premium and medium-grade tobacco leaves) by 14.9 %–24.6 % and 1.6 %–6.3 %, respectively, compared to the CF treatment. These improvements were primarily driven by enhanced plant height, stem girth, number of leaves, leaf area index, biomass, nutrient use efficiency and total sugar, potassium contents. Specifically, WS and OM increased N use efficiency by 106.0 %–130.9 % and 97.4 %–126.1 %, P use efficiency by 62.7 %–149.6 % and 79.2 %–112.4 %, K use efficiency by 473.1 %–551.4 % and 474.6 %–480.5 %, tobacco yield by 20.9 %–24.6 % and 14.9 %–19.1 %, the proportion of premium-grade leaf by 6.5 %–17.2 % and 8.9 %–11.1 %, and tobacco revenue by 26.8 %–29.0 % and 22.8 %–31.5 %, respectively. In summary, both the WS and OM treatments significantly improved the nutrient use efficiency, tobacco yield, leaf quality and revenue; among these, the WS treatment demonstrated the best comprehensive performance. Thus, organic fertilizer combined with water-soluble fertilizer is crucial for promoting the sustainable development of the tobacco industry.
优化营养管理措施是平衡烟草产量和品质的基础。虽然肥料的个别影响已被充分证明,但有机修正剂与水溶性肥料或微生物剂的综合协同作用仍然相对较少。为此,通过为期2年的田间试验,评价了不施肥(CK)、常规化肥(CF)、有机肥与常规化肥(CM)、有机肥与水溶性肥(WS)、有机肥与复合微生物剂(OM) 5种不同营养管理措施对烤烟生长、养分吸收及其利用效率、叶片化学成分、产量、品质、烟叶质量和烟叶质量的综合影响。和收入。结果表明,与CF处理相比,WS和OM处理分别提高了14.9% ~ 24.6%和1.6% ~ 6.3%的烟叶产量和品质(优质和中等烟叶比例)。这些改善主要是由于株高、茎周长、叶数、叶面积指数、生物量、养分利用效率和总糖、钾含量的增加所致。其中,WS和OM分别提高氮素利用效率106.0% ~ 130.9%和97.4% ~ 126.1%,P利用效率62.7% ~ 149.6%和79.2% ~ 112.4%,K利用效率473.1% ~ 551.4%和474.6% ~ 480.5%,烟叶产量分别提高20.9% ~ 24.6%和14.9% ~ 19.1%,优质叶比例分别提高6.5% ~ 17.2%和8.9% ~ 11.1%,烟草收入分别提高26.8% ~ 29.0%和22.8% ~ 31.5%。综上所述,WS和OM处理均显著提高了养分利用效率、烟叶产量、叶品质和收入;其中,WS处理综合性能最好。因此,有机肥与水溶性肥配合施用对促进烟草业的可持续发展至关重要。
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引用次数: 0
Metabolomic profiling, functional, and sensory properties of papads made from two types of rice grown in different conditions 在不同条件下生长的两种水稻叶片的代谢组学分析、功能和感官特性
IF 6.2 Q1 AGRICULTURE, MULTIDISCIPLINARY Pub Date : 2026-03-01 Epub Date: 2026-01-19 DOI: 10.1016/j.jafr.2026.102644
Kamaldeep Kaur, Sonal Aggarwal, Deepika Kathuria, Narpinder Singh
The study aimed to investigate the differences in metabolite profiles between rice varieties cultivated under organic and conventional conditions and to evaluate their suitability for developing high-quality papads (traditional rice-based snacks). Multivariate statistical analyses (PCA and PLS-DA) revealed distinct metabolic clustering between organic and conventional rice samples. Key differentiating metabolites included myo-inositol, glycerol, sucrose, and linoleic acid in polished rice, and oxalic acid, 5-oxoproline, and glycerol-3-phosphate in bran. Papads made from organic rice exhibited higher protein content, greater levels of bioactive compounds, and significantly enhanced antioxidant activity (p < 0.05) compared to those made from conventional rice. Moreover, organic rice papads demonstrated superior functional properties, such as higher oil uptake and water absorption capacity, along with improved texture, sensory acceptability, and microbial stability, resulting in an extended shelf life. Furthermore, papads made from organic rice exhibited higher functional properties (oil uptake and water absorption), improved texture, sensory acceptability, and microbial stability. Hence, the present study highlights the potential of organic farming to enhance the value of traditional agro-products and suggests the need for further research on the long-term sustainability and functional impacts of organic cultivation practices.
该研究旨在调查有机和常规条件下栽培的水稻品种代谢物谱的差异,并评估它们是否适合开发高质量的papads(传统大米零食)。多元统计分析(PCA和PLS-DA)显示有机和常规水稻样品之间存在明显的代谢聚类。主要代谢物包括精米中的肌醇、甘油、蔗糖和亚油酸,麸皮中的草酸、5-氧脯氨酸和甘油-3-磷酸。有机水稻制备的木瓜蛋白含量更高,生物活性化合物含量更高,抗氧化活性显著增强(p < 0.05)。此外,有机稻谷显示出优越的功能特性,如更高的吸油和吸水能力,以及改善的质地、感官接受度和微生物稳定性,从而延长了保质期。此外,由有机水稻制成的木瓜具有更高的功能特性(吸油性和吸水性)、更好的质地、感官可接受性和微生物稳定性。因此,本研究强调了有机农业提高传统农产品价值的潜力,并建议需要进一步研究有机耕作实践的长期可持续性和功能影响。
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引用次数: 0
Impact of intensive greenhouse cultivation on soil health: implications for synergistic management of nutrients and contaminants 集约化温室栽培对土壤健康的影响:对养分和污染物协同管理的影响
IF 6.2 Q1 AGRICULTURE, MULTIDISCIPLINARY Pub Date : 2026-03-01 Epub Date: 2026-01-21 DOI: 10.1016/j.jafr.2026.102707
Linjun Shen , Fangkai Zhao , Junran Li , Lei Yang , Qingyu Feng , Nengliang Yang , Kaifeng Yang , Honglin Liu , Liding Chen
Under long-term greenhouse vegetable production, intensive nutrient inputs enhance crop yields but also lead to the accumulation of antibiotics and heavy metals in greenhouse soils, posing potential risks to crop productivity and soil health. However, studies examining the trade-offs between nutrient inputs and soil contamination remain limited in terms of quantitative assessment of contamination risks. In this study, greenhouse soils with different cultivation histories (<1 year, 5 years, and >10 years) were investigated. The risk quotient (RQ) and a multi-factor heavy metal pollution index (Pt) were used to quantitatively assess the potential risks of soil antibiotics and heavy metals (HMs) contamination to crop growth and soil health, identify key drivers of risks accumulation, and predict contamination risks under different nutrient levels through scenario analyses. The results showed that RQ exhibited “pseudo-persistence” during long-term cultivation and tended to accumulate in lower soil layers, whereas Pt increased continuously with cultivation duration and was predominantly retained in the plow pan layer. Soil nutrients were identified as the key drivers of antibiotic contamination risk, while soil texture played a dominant role in explaining heavy metal contamination risk. Scenario predictions indicated that further increases in nutrient inputs would substantially intensify soil contamination risks; notably, a 10 % increase in soil nutrient levels could elevate antibiotic contamination risk by more than 50 %. This study provides scientific evidence for the coordinated management of nutrient inputs and contamination risks in greenhouse agricultural systems.
在长期温室蔬菜生产中,密集的养分投入提高了作物产量,但也导致抗生素和重金属在温室土壤中积累,对作物生产力和土壤健康构成潜在风险。然而,就污染风险的定量评估而言,审查养分投入和土壤污染之间权衡的研究仍然有限。本研究以不同栽培历史(1年、5年和10年)的温室土壤为研究对象。采用风险商(RQ)和多因素重金属污染指数(Pt)定量评价土壤抗生素和重金属污染对作物生长和土壤健康的潜在风险,识别风险积累的关键驱动因素,并通过情景分析预测不同养分水平下的污染风险。结果表明,RQ在长期耕作过程中表现出“伪持久性”,倾向于在下层土壤中积累,而Pt则随着耕作时间的延长而不断增加,并主要保留在犁盘层中。土壤养分是抗生素污染风险的主要驱动因素,而土壤质地在解释重金属污染风险方面起主导作用。情景预测表明,养分投入的进一步增加将大大加剧土壤污染风险;值得注意的是,土壤养分水平每增加10%,抗生素污染的风险就会增加50%以上。本研究为温室农业系统养分投入与污染风险的协调管理提供了科学依据。
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引用次数: 0
How does renewable energy transition promote food system resilience in China: The moderating role of artificial intelligence 可再生能源转型如何促进中国粮食系统弹性:人工智能的调节作用
IF 6.2 Q1 AGRICULTURE, MULTIDISCIPLINARY Pub Date : 2026-03-01 Epub Date: 2026-01-03 DOI: 10.1016/j.jafr.2026.102637
Jingyi Wang , Shuai Zhang , Haibo Zhu , Xin Dai , Xuebiao Zhang
Investigating how energy transition facilitates food system resilience is crucial for improving food security. The study uses a panel dataset from 30 Chinese provinces over the period 2011–2021 to explore the influence of energy transition on food system resilience by using a series of regression models. The mechanism and heterogeneity analysis are also carried out. Furthermore, the moderating role of artificial intelligence (AI) is discussed. The findings of the feasible generalized least squares regression show that energy transition plays a positive role in promoting food system resilience, and the effect tends to be larger in major grain-producing areas than those in non-major grain-producing areas. AI acts as a moderating variable in the energy transition-food system resilience nexus. Based on these results, we recommend policy strategies that strengthen the efforts to promote energy transition to enhance food system resilience, and also improve the application of AI in this nexus.
调查能源转型如何促进粮食系统恢复力,对于改善粮食安全至关重要。本研究利用2011-2021年中国30个省份的面板数据,通过一系列回归模型探讨能源转型对粮食系统弹性的影响。并对其机理和异质性进行了分析。此外,还讨论了人工智能(AI)的调节作用。可行广义最小二乘回归结果表明,能源转换对粮食系统恢复力有正向促进作用,且主产区的影响大于非主产区。人工智能在能源过渡-粮食系统弹性关系中起调节变量的作用。基于这些结果,我们建议采取政策策略,加强促进能源转型的努力,以提高粮食系统的抵御能力,并改善人工智能在这一领域的应用。
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引用次数: 0
Soil fertility assessment for mango production in karst agroecosystems of Southwest China 西南喀斯特农业生态系统芒果生产土壤肥力评价
IF 6.2 Q1 AGRICULTURE, MULTIDISCIPLINARY Pub Date : 2026-03-01 Epub Date: 2026-01-13 DOI: 10.1016/j.jafr.2026.102655
Yifan Wang , Yujie Zha , Qiuliang Cai , Dianjun Lu , Xiaoqin Chen , Yiliu Wang , Solomon Yokamo , Bin Wang , Xinyuan Lu , Huoyan Wang
Accurate assessment of soil fertility is crucial for enhancing mango productivity and quality. However, rare soil fertility surveys have been reported on mango orchards, especially in karst mountainous areas of China. In this study, an investigation was conducted using 152 paired soil-fruit samples collected from commercial mango orchards in Baise City, Guangxi Province, southwestern China. Principal component analysis (PCA) was employed to establish a minimum data set (MDS), and two distinct weighting methods were compared to calculate the soil integrated fertility index (IFI). The 5 representative indicators—pH, available potassium (AK), organic matter (OM), available phosphorus (AP), and available boron (AB)—were selected to construct the MDS. Together with a correlation-based weighting method, the average IFI was determined to be 0.51 (range: 0.17–0.92), grading the overall fertility as “Medium.” Significant positive correlations were observed between IFI and both yield (R2 = 0.45, p < 0.01) and fruit quality index (FQI) (R2 = 0.49, p < 0.01). Notably, AK and OM were identified as the primary determinants of yield and FQI using random forest model, with 20 g/kg for OM or 120 mg/kg for AK as the critical thresholds for achieving high yields. Furthermore, AP, AB, and altitude were determined as the secondary limiting factors, with corresponding high yield thresholds of 20 mg/kg, 0.30 mg/kg, and 300 m, respectively. These findings provide a theoretical basis and practical guidelines for optimizing orchard establishment and nutrient management in karst agroecosystems.
准确评价土壤肥力对提高芒果产量和品质至关重要。然而,在中国的喀斯特山区,对芒果果园进行了罕见的土壤肥力调查。本研究对广西百色市商品芒果果园的152个配对土壤-果实样本进行了调查。采用主成分分析(PCA)建立最小数据集(MDS),并比较两种不同的加权方法计算土壤综合肥力指数(IFI)。选取ph、速效钾(AK)、有机质(OM)、速效磷(AP)和速效硼(AB) 5个代表性指标构建MDS。结合基于相关性的加权方法,确定平均IFI为0.51(范围:0.17-0.92),将整体生育力评为“中等”。IFI与产量(R2 = 0.45, p < 0.01)和果实品质指数(FQI)均呈极显著正相关(R2 = 0.49, p < 0.01)。值得注意的是,利用随机森林模型确定速效钾和速效钾是产量和FQI的主要决定因素,速效钾20 g/kg或速效钾120 mg/kg是实现高产的关键阈值。此外,确定AP、AB和海拔为次要限制因素,相应的高产阈值分别为20 mg/kg、0.30 mg/kg和300 m。研究结果为优化喀斯特农业生态系统果园建设和养分管理提供了理论依据和实践指导。
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引用次数: 0
The effect of climate shocks on food price inflation, India 气候冲击对食品价格通胀的影响,印度
IF 6.2 Q1 AGRICULTURE, MULTIDISCIPLINARY Pub Date : 2026-03-01 Epub Date: 2026-01-08 DOI: 10.1016/j.jafr.2026.102636
M. Santhosh Kumar , N. Venkatesa Palanichamy , K.M. ShivaKumar , M. Chandrakumar , M. Kalpana , D. Murugananthi
Climate shocks are reshaping food price dynamics in India, with implications for macroeconomic stability and stabilization policy. This study estimates the dynamic effects of droughts, extreme temperatures, floods, and storms on food inflation using annual data for 1970–2024 and the local projections framework (horizons k = 0 … 5). Climate shocks are measured both as (i) binary event indicators and (ii) population-adjusted intensity (deaths per 100,000), winsorized and standardized. Estimation uses OLS with HAC/Newey–West standard errors and controls for inflation persistence, lagged shocks, output gap, monetary conditions, and external-sector variables. Results show strong heterogeneity across shock types. In intensity specifications, drought intensity raises cumulative food inflation in the medium run, becoming significantly positive by k = 3 (β = 0.5245∗∗∗) and peaking at k = 4 (β = 1.2154∗∗∗), with a still-positive effect at k = 5 (β = 0.4626∗∗∗). Flood intensity produces short-run disinflation (k = 1: β = −1.5215∗∗) but turns positive by k = 5 (β = 1.1597∗), consistent with stabilization policy followed by delayed catch-up. Storm intensity shows short-run disinflation (k = 1: β = −1.1304∗∗; k = 2: β = −1.2764∗) while extreme temperature intensity is negative and significant at k = 2 (β = −0.9971∗∗). State-dependent estimates indicate materially different transmission in slack conditions, reinforcing the role of macro context in climate–price pass-through. Policy implications emphasize drought-resilience investments (irrigation, climate-resilient seeds, buffer stocks), rapid post-flood logistics restoration, and explicit integration of climate risk into inflation forecasting and food-market stabilization.
气候冲击正在重塑印度的粮食价格动态,对宏观经济稳定和稳定政策产生影响。本研究使用1970-2024年的年度数据和当地预测框架(视界k = 0…5)估计了干旱、极端温度、洪水和风暴对食品通胀的动态影响。气候冲击以(i)二元事件指标和(ii)人口调整强度(每10万人死亡人数)进行计量,并进行了加权和标准化。估计使用具有HAC/ new - west标准误差的OLS,并控制通货膨胀持续性、滞后冲击、产出缺口、货币状况和外部部门变量。结果显示不同类型的冲击具有很强的异质性。在强度规格中,干旱强度在中期提高了累积食品通货膨胀,在k = 3 (β = 0.5245∗∗)时变为显著正值,在k = 4 (β = 1.2154∗∗)时达到峰值,在k = 5 (β = 0.4626∗∗)时仍然具有正效应。洪水强度产生短期反通货膨胀(k = 1: β = - 1.5215∗),但在k = 5 (β = 1.1597∗)时转为正通货膨胀,这与随后的延迟追赶的稳定政策一致。风暴强度表现出短期的反膨胀(k = 1: β =−1.1304 * *;k = 2: β =−1.2764 * *),而极端温度强度在k = 2时为负且显著(β =−0.9971 * *)。依赖于国家的估计表明,在疲软条件下的传输有很大不同,这加强了宏观环境在气候价格传递中的作用。政策影响强调抗旱投资(灌溉、气候适应型种子、缓冲库存)、灾后物流快速恢复,以及将气候风险明确纳入通胀预测和粮食市场稳定。
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引用次数: 0
Production and consumption trends of Bili-bili marketed in N'Djamena (Chad): Socio-economic and cultural importance, physico-chemical and hygienic characterization 在乍得恩贾梅纳销售的Bili-bili的生产和消费趋势:社会经济和文化重要性、物理化学和卫生特性
IF 6.2 Q1 AGRICULTURE, MULTIDISCIPLINARY Pub Date : 2026-03-01 Epub Date: 2026-01-27 DOI: 10.1016/j.jafr.2026.102720
Saturnin Naïm , Laverdure Tchamani Piame , Edith Marius Foko Kouam , Michele Létitia Tchabou Tientcheu , Maxime Merlin Djoufack Tonfack , François Zambou Ngoufack , Pierre Marie Kaktcham
In recent years, low-income consumers of alcoholic beverages in Chad have converged more towards indigenous beverages, such as Bili-bili. Its production and commercialization, is mostly carried out in unhygienic conditions and often in the grey zone, out of the full control of the Chadian government. This study aims to assess socio-economic and cultural importance of Bili-bili commercialized in N'Djamena (Chad) and its physico-chemical and hygienic characteristics. Firstly, a survey was carried among 715 producers and 795 consumers of Bili-bili. Secondly, forty-five samples of Bili-bili were collected and then used to determine the physico-chemical and microbiological characteristics using standard methods. As a result, Bili-bili was produced exclusively by women, of whom 99.3 % considered as a source of income. Beyond being very used in many traditional ceremonies (78.07 %), the consumption of Bili-bili was motivated by its relatively low cost compared to modern alcoholic beers (56.5 %) and its nourishing aptitude (31.9 %). In lasted case, 65.4 % consume it for the pleasure provided by the alcohol content. Also, Bili-bili could not be kept for more than 24 h with a consistent taste (78.16 %). Its consumption sometimes produces undesirable effects in consumers, such as gastric upset, diarrhea, and vomiting (66.62 %), as well as stomach and headache (32.45 %). The Bili-bili produced had a pH (2.99–4.21) and a composition made of proteins (5.63–12.37 %), lipids (0.03–3.78 %), carbohydrates (81.33–89.23 %) and ethanol (2.33–4.60 g/L). Some samples contained aflatoxin (0.13–1.20 μg/L). The microflora included yeasts (7.39–9.36 log CFU/mL), lactic bacteria (7.11–8.44 log CFU/mL), molds (0.45-0. 78 log CFU/mL), Bacillus cereus (3.33–7.61 log CFU/mL) and sulfite-reducing bacteria (0.75–2.08 log CFU/mL). Bili-bili production has a remarkable socio-economic and cultural importance. However, its hygienic quality remains mediocre, making it a spread of spoilage and/or pathogenic bacteria.
近年来,乍得酒精饮料的低收入消费者更倾向于购买本土饮料,如Bili-bili。它的生产和商业化大多是在不卫生的条件下进行的,往往在灰色地带,不受乍得政府的完全控制。本研究旨在评估在乍得恩贾梅纳商业化的Bili-bili的社会经济和文化重要性及其物理化学和卫生特性。首先,对bilibili的715个生产者和795个消费者进行了调查。其次,采集哔哩哔哩45份样品,采用标准方法测定其理化和微生物特性。因此,bilii -bili完全由女性制作,其中99.3%被视为收入来源。除了在许多传统仪式中被广泛使用(78.07%)外,与现代含酒精啤酒(56.5%)相比,哔哩哔哩的价格相对较低,而且它的营养价值(31.9%)也是推动哔哩哔哩消费的原因。在最后一种情况下,65.4%的人消费它是为了酒精含量所提供的快感。此外,bilibili -bili保存时间不能超过24 h且味道一致(78.16%)。食用它有时会对消费者产生不良影响,如胃不适、腹泻和呕吐(66.62%),以及胃和头痛(32.45%)。所得Bili-bili的pH值为2.99 ~ 4.21,由蛋白质(5.63 ~ 12.37%)、脂类(0.03 ~ 3.78%)、碳水化合物(81.33 ~ 89.23%)和乙醇(2.33 ~ 4.60 g/L)组成。部分样品黄曲霉毒素含量为0.13 ~ 1.20 μg/L。微生物区系包括酵母菌(7.39 ~ 9.36 log CFU/mL)、乳酸菌(7.11 ~ 8.44 log CFU/mL)、霉菌(0.45 ~ 0。78 log CFU/mL),蜡样芽孢杆菌(3.33-7.61 log CFU/mL)和亚硫酸盐还原菌(0.75-2.08 log CFU/mL)。哔哩哔哩制作具有显著的社会经济和文化重要性。然而,它的卫生质量仍然一般,使它成为腐败和/或致病菌的传播。
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引用次数: 0
Glutathione-rich yeast extract improves alcohol-associated liver diseases through the improvement of mitochondrial dysfunction and oxidative stress by activating SIRT3 富含谷胱甘肽的酵母提取物通过激活SIRT3改善线粒体功能障碍和氧化应激,改善酒精相关肝脏疾病
IF 6.2 Q1 AGRICULTURE, MULTIDISCIPLINARY Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.jafr.2026.102735
Hao Han , Yanyang Han , Yajing Dong , Shuqi Ji , Xiaoman Wang , Yuantong Yu , Xingxing Che
Alcohol-associated liver diseases (ALD) is a chronic liver disease characterized by mitochondrial dysfunction and oxidative stress. Glutathione (GSH)-rich yeast extract (GYE) is a product abundant in proteins, amino acids, fiber, trace elements, and GSH. Previous studies have reported that GYE exhibits anti-inflammatory and antioxidant properties. However, the effect of GYE on ALD and its underlying mechanisms remain largely unclear. In the present study, we investigated whether GYE could protect against ALD using ethanol-treated mice and HepG2 cells, with a specific focus on mechanisms involving the amelioration of ethanol-induced mitochondrial damage and oxidative stress. The results showed that GYE significantly ameliorated liver injury in chronic ethanol-feeding mice. In addition, GYE increased the content of GSH in the liver, thereby protecting against ethanol-induced oxidative stress and mitochondrial dysfunction. Moreover, the expression of SIRT3 was measured to reveal potential targets by which GYE protected against ALD. Our results showed that the ethanol-induced inhibition of SIRT3 expression was reversed by GYE in vivo and in vitro. Silencing of SIRT3 by siRNA markedly weakened the protective effect of GYE on mitochondrial function and oxidative stress. Our findings suggest that GYE alleviates ethanol-induced mitochondrial damage and oxidative stress via activating SIRT3 in an ALD mouse model, which highlights a promising prevention strategy for ALD.
酒精相关性肝病(ALD)是一种以线粒体功能障碍和氧化应激为特征的慢性肝病。富含谷胱甘肽(GSH)酵母提取物(GYE)是一种富含蛋白质、氨基酸、纤维、微量元素和谷胱甘肽的产品。先前的研究报道了GYE具有抗炎和抗氧化特性。然而,GYE对ALD的影响及其潜在机制在很大程度上仍不清楚。在本研究中,我们用乙醇处理的小鼠和HepG2细胞研究了GYE是否可以预防ALD,并特别关注了涉及改善乙醇诱导的线粒体损伤和氧化应激的机制。结果表明,GYE能显著改善慢性乙醇喂养小鼠的肝损伤。此外,GYE增加肝脏中谷胱甘肽的含量,从而防止乙醇诱导的氧化应激和线粒体功能障碍。此外,我们测量了SIRT3的表达,以揭示GYE保护ALD的潜在靶点。我们的研究结果表明,乙醇诱导的SIRT3表达抑制在体内和体外被GYE逆转。siRNA沉默SIRT3后,GYE对线粒体功能和氧化应激的保护作用明显减弱。我们的研究结果表明,GYE通过激活ALD小鼠模型中的SIRT3来减轻乙醇诱导的线粒体损伤和氧化应激,这突出了一种有希望的ALD预防策略。
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引用次数: 0
Nitrogen composition in cv. Monastrell berries under climate change: The role of vineyard management cv中的氮组成。气候变化下的Monastrell浆果:葡萄园管理的作用
IF 6.2 Q1 AGRICULTURE, MULTIDISCIPLINARY Pub Date : 2026-03-01 Epub Date: 2026-01-14 DOI: 10.1016/j.jafr.2026.102663
M. Esperanza Valdés , Laura Martín , Álvaro Vergara , Raquel Pavo , M. Victoria Alarcón , M. Mar Alguacil
Environmental conditions strongly influence grape amino acid profiles, which are key for fermentation and wine aroma. However, the combined effects of climate-driven warming and reduced rainfall together with vineyard management on berry amino acid composition remain poorly understood under field conditions. This study evaluated the effects of warming (W) and reduced rainfall (RR) on the nitrogen composition of cv. Monastrell berries under conventional (CON) and organic (ORG) vineyard management systems. A field experiment was established in 2023 in a rainfed vineyard (Murcia, SE Spain) using open-top chambers and rain-exclusion shelters to simulate warming and reduced rainfall respectively, with ambient conditions as controls. Individual amino acids and ammonium were analyzed by HPLC at harvest in 2023 and 2024, and nitrogen parameters including total free amino acids (FAN), yeast-assimilable nitrogen (YAN) and precursor aromatic nitrogen (PAN) were determined. ORG management showed higher amino acid concentrations than CON, with increases exceeding 100 % for GABA and proline. In 2023, climate treatments significantly affected 13 amino acids, whereas vineyard management effects and vineyard management × climate interactions were each significant for 4. Warming increased FAN, AAN, YAN and PAN by 25–75 % under ORG and by 111–160 % under CON, while ammonium increased by 96 % and 28 % under ORG and CON, respectively. Reduced rainfall had negligible effects in both years, confirming temperature as the dominant driver. These findings indicate that warming strongly alters grape nitrogen metabolism, whereas organic management mitigates its impact, supporting its role as a sustainable strategy to preserve nitrogen compounds under future climate scenarios.
环境条件强烈影响葡萄的氨基酸谱,而氨基酸谱是发酵和葡萄酒香气的关键。然而,在田间条件下,气候变暖和降雨量减少以及葡萄园管理对浆果氨基酸组成的综合影响仍然知之甚少。本研究评价了增温(W)和降雨减少(RR)对土壤氮素组成的影响。传统(CON)和有机(ORG)葡萄园管理制度下的蒙斯特雷尔浆果。2023年,在一个雨养葡萄园(西班牙东南部穆尔西亚)建立了一个田间试验,在环境条件为对照的情况下,使用开顶室和防雨棚分别模拟增温和减少降雨。2023年和2024年收获时,采用高效液相色谱法分析了单个氨基酸和铵态氮,测定了总游离氨基酸(FAN)、酵母可同化氮(YAN)和前体芳香氮(PAN)等氮参数。ORG处理的氨基酸浓度高于CON,其中GABA和脯氨酸的含量增加超过100%。2023年,气候处理显著影响了13种氨基酸,而葡萄园管理效应和葡萄园管理与气候交互作用各影响了4种氨基酸。增温使ORG和CON处理下的FAN、AAN、YAN和PAN分别增加了25 ~ 75%和111 ~ 160%,而铵处理下分别增加了96%和28%。在这两年,降雨量减少的影响可以忽略不计,这证实了温度是主要的驱动因素。这些发现表明,变暖强烈地改变了葡萄的氮代谢,而有机管理减轻了其影响,支持其作为未来气候情景下保护氮化合物的可持续策略的作用。
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引用次数: 0
Drought and low nitrogen impact on finger millet yield and grain nutrition 干旱和低氮对小谷子产量和籽粒营养的影响
IF 6.2 Q1 AGRICULTURE, MULTIDISCIPLINARY Pub Date : 2026-03-01 Epub Date: 2026-01-03 DOI: 10.1016/j.jafr.2026.102634
Chami Rampati Dewage , Mohan K. Bista , Nuwan K. Wijewardane , Raju Bheemanahalli
Dry and nutrient-poor soils pose a significant threat to food and nutritional security. Finger millet (Eleusine coracana [L.] Gaertn.), a climate-resilient nutraceutical crop, shows promise in such soils. However, reproductive-stage performance of this crop under low-nitrogen and drought conditions has been overlooked relative to that of major cereals. This study evaluated the growth, yield, and grain nutrient-related trait responses of finger millet under control (CNT), low nitrogen (LN), drought stress (DS), and combined LN + DS conditions. Although all stresses imposed at flowering delayed days to maturity, DS had a greater negative impact on yield components, whereas LN significantly affected grain nutrient content. The yield loss was highest under combined stress (54 %), followed by DS (30 %) and LN (15 %). Although the harvest index remained stable under individual stress, it declined by 25 % under combined stress. The phosphorus, potassium, calcium, sulfur, and iron content of grain remained unchanged under all stresses. However, nitrogen under DS and copper, zinc, and boron under LN increased significantly. Therefore, the observed increases likely reflect a combination of concentration effects and sustained or improved nutrient uptake and remobilization, rather than seed size reduction alone. Yield components responded in the order LN + DS > DS > LN, while grain nutrient responses were highest under LN and LN + DS and lowest under DS. This study highlights resilience and biofortification potential of finger millet under marginal soils. Future studies should prioritize elucidating the molecular mechanisms that regulate multi-stress tolerance during the critical growth stage.
干旱和贫瘠的土壤对粮食和营养安全构成重大威胁。谷子[L];[Gaertn.],一种适应气候变化的营养作物,在这样的土壤中显示出希望。然而,与主要谷物相比,这种作物在低氮和干旱条件下的生育期表现被忽视了。本研究评价了在对照(CNT)、低氮(LN)、干旱(DS)和低氮+干旱联合胁迫条件下手指粟生长、产量和籽粒营养相关性状的响应。花期胁迫对籽粒营养成分的影响较大,而低温胁迫对籽粒营养成分的影响较大。复合胁迫下产量损失最大(54%),其次是DS(30%)和LN(15%)。个别胁迫下收获指数保持稳定,但复合胁迫下下降25%。籽粒的磷、钾、钙、硫、铁含量在不同胁迫下均保持不变。而DS处理下氮含量和LN处理下铜、锌、硼含量显著增加。因此,观察到的增加可能反映了浓度效应和持续或改善的养分吸收和再动员的结合,而不仅仅是种子大小的减少。产量成分响应顺序为LN + DS >; DS >; LN, LN + DS下籽粒养分响应最高,DS下最低。本研究强调了边缘土壤下小谷的恢复力和生物强化潜力。未来的研究应优先阐明关键生长阶段调控多逆境耐受性的分子机制。
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Journal of Agriculture and Food Research
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