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Bioactive Glass Graft vs Allograft in Benign Bone Lesions: A Retrospective Comparative Study. 生物活性玻璃移植物与同种异体移植物治疗良性骨病变的回顾性比较研究。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-03-20 DOI: 10.1177/15563316251321825
Mustafa Alper Incesoy, Murat Sarikas, Hakan Batuhan Kaya, Ahmet Durcan Yavuz, Bilal Sulak, Asena Ayca Ozdemir, Ali Can Ozarslan, Gokcer Uzer, Fatih Yıldız, Sevil Yucel, Volkan Gurkan

Background: Bioactive glass (BG) is a promising alternative to conventional autogenous and allogeneic bone grafts with osteoconductive, osteoinductive, and antimicrobial properties. The effects of its use in comparison to allograft in the context of benign bone lesions remain less explored.

Purpose: We sought to compare the efficacy of 45S5 BG granules to allograft in treating benign bone lesions.

Methods: This retrospective study compared the outcomes of 45S5 BG granules and allograft bone in 42 patients undergoing curettage for benign bone lesions. Patients were divided into 2 groups based on the graft material used (n = 21 in each group). Radiological evaluation using the modified Neer classification and functional assessment using the Musculoskeletal Tumor Society (MSTS) score were performed. Complications and time to return to previous activity levels were also recorded.

Results: No significant differences were found between the BG and allograft groups in terms of postoperative Neer scores, postoperative MSTS scores, complication rates, or time to return to previous activity levels. Both groups showed significant improvement in MSTS scores over time, although improvement in MSTS scores for both groups did not reach the minimal clinically important difference, suggesting that the observed changes may not be clinically significant.

Conclusion: This retrospective study found that BG demonstrated comparable efficacy to allograft cancellous bone in the treatment of benign bone lesions, suggesting that it may serve as a suitable alternative. Further study should focus on longer-term follow-up and larger sample sizes to further elucidate the role of BG in the management of these lesions.

背景:生物活性玻璃(BG)具有骨导电性、骨诱导性和抗菌性,是传统自体和异体骨移植物的一种很有前途的替代品。与同种异体骨移植相比,其在良性骨病变中的应用效果尚不明确。目的:比较45S5 BG颗粒与同种异体骨移植治疗良性骨病变的疗效。方法:回顾性比较45S5 BG颗粒和同种异体骨移植在42例良性骨病变刮除术中的效果。根据所使用的移植物材料将患者分为两组(每组21例)。采用改良的Neer分类进行放射学评估,使用肌肉骨骼肿瘤学会(MSTS)评分进行功能评估。同时记录并发症和恢复到以前活动水平的时间。结果:BG组和同种异体移植物组在术后Neer评分、术后MSTS评分、并发症发生率或恢复到先前活动水平的时间方面无显著差异。随着时间的推移,两组的MSTS评分均有显著改善,但两组的MSTS评分改善均未达到临床重要差异的最小值,提示观察到的变化可能不具有临床意义。结论:本回顾性研究发现BG与同种异体松质骨移植治疗良性骨病变的疗效相当,提示BG可能是一种合适的替代方案。进一步的研究应侧重于长期随访和更大的样本量,以进一步阐明BG在这些病变管理中的作用。
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引用次数: 0
Stratified Comparison of Short-Term Perioperative Outcomes in Direct Anterior Versus Posterolateral Primary Total Hip Arthroplasty: A Retrospective Review. 直接前、后外侧全髋关节置换术短期围手术期疗效的分层比较:回顾性回顾。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-03-14 DOI: 10.1177/15563316251323612
Colin C Neitzke, Pravjit Bhatti, Sonia K Chandi, Ranqing Lan, Elizabeth B Gausden, Peter K Sculco, Brian P Chalmers

Background: It is unclear what influence patient sex and body mass index (BMI) have on perioperative outcomes following total hip arthroplasty (THA), especially regarding anterior versus posterolateral approaches. Purpose/Study Questions: We sought to compare perioperative outcomes of primary THA via direct anterior (DAA) versus posterolateral (PLA) approaches, stratified by patient sex and BMI. Methods: A retrospective review at a single institution identified 8258 patients 18 to 80 years old who underwent primary THA via DAA or PLA for osteoarthritis between February 2019 and April 2022. Patients were stratified by sex and BMI (<30 or 30-40). We compared operative times, lengths of stay (LOS), opioid consumption and prescribing patterns, and achievement of Hip Injury and Osteoarthritis Outcome Score for Joint Replacement (HOOS JR) minimum clinically important difference (MCID), substantial clinical benefit (SCB), and patient acceptable symptom state (PASS) across the cohorts. Results: Median operative time was 6 to 11 minutes longer for DAA than for PLA. Median LOS was shorter for DAA, with the largest difference observed in women with BMI <30 (19-hour difference) and BMI 30 to 40 (20-hour difference). In-hospital milligram morphine equivalents consumed were lower for DAA in men with BMI <30 (45 vs 53), women with BMI <30 (45 vs 53), and women with BMI 30-40 (60 vs 75). There was no difference observed in HOOS JR MCID, SCB, or PASS achievement scores at 1 year for any cohort. Conclusion: This retrospective study found longer operative times for DAA than PLA and shorter LOS in women undergoing DAA than those undergoing PLA. There were minimal clinical differences in in-hospital opioid consumption, 90-day opioid prescription patterns, and patient-reported outcome measures. These findings suggest that patient sex and BMI may have implications on case scheduling and discharge planning for primary THA. Further study is warranted.

背景:目前尚不清楚患者性别和体重指数(BMI)对全髋关节置换术(THA)围手术期预后的影响,尤其是前路与后外侧入路。目的/研究问题:我们试图比较经直接前路(DAA)和后外侧(PLA)入路原发性THA的围手术期结果,并按患者性别和BMI进行分层。方法:在2019年2月至2022年4月期间,对一家机构的8258名18至80岁的患者进行回顾性研究,这些患者通过DAA或PLA接受了原发性骨关节炎THA。患者按性别和BMI进行分层(结果:DAA的中位手术时间比PLA的中位手术时间长6至11分钟。结论:本回顾性研究发现DAA手术时间长于PLA, DAA患者的LOS短于PLA患者。在院内阿片类药物消费、90天阿片类药物处方模式和患者报告的结果测量方面,临床差异很小。这些发现表明,患者性别和BMI可能对原发性THA的病例安排和出院计划有影响。值得进一步研究。
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引用次数: 0
Finding the Right Doctor: Not So Easy! 找到合适的医生:没那么容易!
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-02-27 DOI: 10.1177/15563316251321816
Douglas E Padgett
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引用次数: 0
Robotic-Assisted Navigation in Single-Level Transforaminal Lumbar Interbody Fusion Reduces Surgeons' Mental Workload Compared With Fluoroscopic and Computed Tomographic Techniques: A Nonrandomized Prospective Controlled Trial. 与透视和计算机断层扫描技术相比,机器人辅助导航在单层经椎间孔腰椎椎体融合术中可减轻外科医生的脑力劳动负担:一项非随机前瞻性对照试验。
IF 1.3 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-10-06 DOI: 10.1177/15563316241281064
Kyle W Morse, Tejas Subramanian, Eric Zhao, Omri Maayan, Yousi Oquendo, Catherine Himo Gang, James Dowdell, Sheeraz Qureshi, Sravisht Iyer

Background: Pedicle screw placement during spine fusion is physically and mentally demanding for surgeons. Consequently, spine surgeons can become fatigued, which has implications for both patient safety and surgeon well-being.

Purpose: We sought to assess the cognitive workload of surgeons placing pedicle screws using robotic-assisted navigation compared with fluoroscopic and computed tomography (CT)-assisted placement.

Methods: We performed a nonrandomized prospective controlled trial to compare the cognitive workload of 3 surgeons performing single-level minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) using robotic, CT, or fluoroscopic navigation on 25 patients (15 in the robotic navigation group and 10 in the nonrobotic group). Immediately after each procedure, surgeons submitted the National Aeronautics and Space Administration-Task Load Index (NASA-TLX), which has 6 subscales: mental demands, physical demands, temporal demands, performance, effort, and frustration. Four tasks associated with pedicle screw placement were assessed independently: (1) screw planning, (2) calibrating robot/obtaining imaging/registration, (3) pedicle cannulation, and (4) screw placement. Patient demographics and surgical characteristics were obtained and reviewed.

Results: Surgeons' self-reported cognitive workload was significantly reduced when using robotic-assisted navigation versus CT/fluoroscopic navigation. Workload was reduced for screw planning, pedicle cannulation, and screw placement. In addition, there were significant reductions in each subdomain for these 3 tasks, encompassing mental demand, physical demand, temporal demand, effort, and frustration with improved task performance.

Conclusions: This study found significant reductions in mental workload with improved perceived performance for robotic-assisted pedicle screw placement compared with fluoroscopic and CT-navigation techniques. Lowering the cognitive burden associated with screw placement may allow surgeons to address the remainder of the operative case with less decision fatigue, prevent complications, and increase surgeon wellness.

背景:脊柱融合术中的椎弓根螺钉置入对外科医生的体力和脑力要求都很高。目的:与透视和计算机断层扫描(CT)辅助椎弓根螺钉置入相比,我们试图评估外科医生使用机器人辅助导航置入椎弓根螺钉的认知工作量:我们进行了一项非随机前瞻性对照试验,比较了使用机器人、CT 或透视导航对 25 名患者(机器人导航组 15 名,非机器人组 10 名)进行单层微创经椎间孔腰椎椎体融合术(MI-TLIF)的 3 名外科医生的认知工作量。每次手术后,外科医生都会立即提交美国国家航空航天局任务负荷指数(NASA-TLX),该指数包含 6 个分量表:心理需求、体力需求、时间需求、表现、努力和挫败感。对与椎弓根螺钉置入相关的四项任务进行了独立评估:(1)螺钉规划,(2)校准机器人/获取成像/注册,(3)椎弓根插管,以及(4)螺钉置入。对患者的人口统计学和手术特征进行了了解和审查:结果:使用机器人辅助导航与CT/荧光屏导航相比,外科医生自我报告的认知工作量明显减少。螺钉规划、椎弓根插管和螺钉置入的工作量均有所减少。此外,这3项任务的每个子域(包括心理需求、体力需求、时间需求、努力和挫败感)的工作量都有明显减少,任务绩效也有所提高:本研究发现,与透视和CT导航技术相比,机器人辅助椎弓根螺钉置入术的脑力劳动负荷明显减轻,认知能力也有所提高。减轻螺钉置入的认知负担可使外科医生在处理剩余手术病例时减少决策疲劳、预防并发症并提高外科医生的健康水平。
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引用次数: 0
Recall of Orthopedic Implants Must Be Addressed. 必须解决骨科植入物召回问题。
IF 1.3 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-08-15 DOI: 10.1177/15563316241268084
Charles N Cornell
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引用次数: 0
Arthroscopic Reverse Remplissage for Treatment of Recurrent Posterior Shoulder Instability: Technique Description and Case Report. 关节镜下反向复位治疗复发性后肩不稳:技术描述及病例报告。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-01-29 DOI: 10.1177/15563316241313380
Nicole M Mahr, Christopher M Belyea, Nathan S Lanham
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引用次数: 0
Preoperative Ultrasound Correctly Localized Peripheral Nerve Abnormalities for Operative Guidance: A Retrospective Review. 术前超声正确定位周围神经异常以指导手术:回顾性回顾。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-01-29 DOI: 10.1177/15563316251313807
Noah Cha, Esther Zusstone, Lydia Ko, Steve K Lee, Carlo J Milani, Joseph H Feinberg, Scott W Wolfe, O Kenechi Nwawka

Background: Correct localization and characterization of nerve abnormality is of critical importance to appropriate intervention. Ultrasound (US) is known to be accurate in the diagnosis of peripheral neuropathy and in preoperative localization of nerve abnormalities and skin marking.

Purpose: We sought to investigate the utility of US-guided preoperative skin marking for the localization of peripheral nerve abnormality and to compare the US findings to electrodiagnostic (EDx) reports.

Methods: Using the radiology information system at a single institution, we identified US examinations performed for preoperative localization of peripheral nerve abnormality from July 2016 to March 2023. Data collected included US characterization, surgical description, and EDx report of neuropathy.

Results: Search parameters identified 67 nerves in 55 patients treated surgically after US-guided localization of the nerve with skin marking. The EDx characterization was performed in 36 (54%) of these cases. The US diagnoses included neuroma, transection, perineural scarring, hardware impingement, and intraneural fascicular constriction. There was 100% accuracy of US findings as confirmed by operative notes. Skin marking by US guidance correlated to the sites of the nerve documented in operative reports of all 67 cases.

Conclusion: In this single-institution retrospective review, US-guided preoperative skin marking of nerve abnormality was used to correctly localize peripheral nerve abnormality, and US diagnoses were corroborated by intraoperative findings. Further higher-level study is needed to support these findings suggesting the efficacy of US in mapping the course of peripheral nerves.

背景:神经异常的正确定位和特征对适当的干预至关重要。超声(US)被认为是准确的周围神经病变的诊断和术前定位神经异常和皮肤标记。目的:我们试图研究超声引导下术前皮肤标记对周围神经异常定位的作用,并将超声结果与电诊断(EDx)报告进行比较。方法:利用单一机构的放射学信息系统,我们确定了2016年7月至2023年3月期间进行的周围神经异常术前定位的US检查。收集的数据包括US特征、手术描述和神经病变的EDx报告。结果:搜索参数确定了55例经us引导的皮肤标记神经定位手术的患者中的67条神经。其中36例(54%)进行了EDx表征。美国诊断包括神经瘤、横断、神经周围瘢痕、硬体撞击和神经内束缩窄。手术记录证实,超声检查结果100%准确。在所有67例的手术报告中,由US引导的皮肤标记与神经的位置相关。结论:在这项单机构回顾性研究中,US引导下的术前神经异常皮肤标记能够正确定位周围神经异常,术中发现也证实了US诊断。需要进一步的高水平的研究来支持这些发现,表明US在绘制周围神经路线方面的功效。
{"title":"Preoperative Ultrasound Correctly Localized Peripheral Nerve Abnormalities for Operative Guidance: A Retrospective Review.","authors":"Noah Cha, Esther Zusstone, Lydia Ko, Steve K Lee, Carlo J Milani, Joseph H Feinberg, Scott W Wolfe, O Kenechi Nwawka","doi":"10.1177/15563316251313807","DOIUrl":"10.1177/15563316251313807","url":null,"abstract":"<p><strong>Background: </strong>Correct localization and characterization of nerve abnormality is of critical importance to appropriate intervention. Ultrasound (US) is known to be accurate in the diagnosis of peripheral neuropathy and in preoperative localization of nerve abnormalities and skin marking.</p><p><strong>Purpose: </strong>We sought to investigate the utility of US-guided preoperative skin marking for the localization of peripheral nerve abnormality and to compare the US findings to electrodiagnostic (EDx) reports.</p><p><strong>Methods: </strong>Using the radiology information system at a single institution, we identified US examinations performed for preoperative localization of peripheral nerve abnormality from July 2016 to March 2023. Data collected included US characterization, surgical description, and EDx report of neuropathy.</p><p><strong>Results: </strong>Search parameters identified 67 nerves in 55 patients treated surgically after US-guided localization of the nerve with skin marking. The EDx characterization was performed in 36 (54%) of these cases. The US diagnoses included neuroma, transection, perineural scarring, hardware impingement, and intraneural fascicular constriction. There was 100% accuracy of US findings as confirmed by operative notes. Skin marking by US guidance correlated to the sites of the nerve documented in operative reports of all 67 cases.</p><p><strong>Conclusion: </strong>In this single-institution retrospective review, US-guided preoperative skin marking of nerve abnormality was used to correctly localize peripheral nerve abnormality, and US diagnoses were corroborated by intraoperative findings. Further higher-level study is needed to support these findings suggesting the efficacy of US in mapping the course of peripheral nerves.</p>","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":" ","pages":"15563316251313807"},"PeriodicalIF":1.6,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Application of Clinical Practice Guideline Recommendations on the Classification of Patients With Neck Pain. 颈痛患者分类临床实践指南建议的应用评价。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-01-08 DOI: 10.1177/15563316241309351
Michelle M Ramirez, Marissa Carvalho, Katie Pruka, Derek Clewley, Charlotte Selters, Alexandra Lonner, Hayley Phillips, Gerard P Brennan, Steven Z George, Maggie E Horn

Background: Clinical practice guidelines (CPGs) are developed to synthesize evidence into recommendations for clinical practice. Minimal evidence exists on the evaluation practice of physical therapists in the treatment of patients with neck pain. Purpose: We sought to describe (1) the extent to which clinicians perform the Neck Pain CPG-recommended examination measures and (2) the percentage of patients properly classified. Methods: We retrospectively analyzed the electronic health records of 397 patients with neck pain at an ambulatory care setting in an academic medical center. The frequency of physical therapists' evaluation measures, subjective findings, positive examination results, and the percentage of patients properly classified into impairment-based categories (IBCs) were recorded. Descriptive statistics and χ2 tests were used to assess patient demographics and compare classification accuracy across IBCs. Results: Of the 397 patients, 56% were classified into an IBC. The most common IBC was neck pain with mobility deficits (24%), followed by neck pain with radiating pain (17%), neck pain with movement coordination impairments (NPMCIs) (8%), and neck pain with headache (6%). Neck pain with movement coordination impairment had the lowest percentage of proper classifications. Classification accuracy was highest when subjective and objective findings were combined and varied between IBCs. Conclusion: Our findings suggest that physical therapists evaluating patients with neck pain may have increased classification accuracy when subjective and objective findings are considered. Decreased classification accuracy was demonstrated in the NPMCI category, highlighting opportunities for further education and research.

背景:临床实践指南(CPGs)的制定是为了将证据综合为临床实践的建议。很少有证据表明物理治疗师在治疗颈部疼痛患者时的评估实践。目的:我们试图描述(1)临床医生执行cpg推荐的颈部疼痛检查措施的程度和(2)正确分类的患者百分比。方法:回顾性分析某学术医疗中心门诊397例颈部疼痛患者的电子病历。记录物理治疗师评估措施的频率、主观发现、阳性检查结果以及适当归类为损伤分类(IBCs)的患者百分比。采用描述性统计和χ2检验评估患者人口统计学特征,比较IBCs的分类准确性。结果:397例患者中,56%归为IBC。最常见的IBC是颈部疼痛伴活动能力不足(24%),其次是颈部疼痛伴放射性疼痛(17%),颈部疼痛伴运动协调障碍(NPMCIs)(8%)和颈部疼痛伴头痛(6%)。颈部疼痛伴运动协调障碍的适当分类比例最低。当主观和客观结果相结合并在IBCs之间变化时,分类准确性最高。结论:我们的研究结果表明,当考虑到主观和客观的发现时,物理治疗师评估颈部疼痛患者的分类准确性可能会提高。在NPMCI类别中,分类准确性下降,突出了进一步教育和研究的机会。
{"title":"Evaluation of the Application of Clinical Practice Guideline Recommendations on the Classification of Patients With Neck Pain.","authors":"Michelle M Ramirez, Marissa Carvalho, Katie Pruka, Derek Clewley, Charlotte Selters, Alexandra Lonner, Hayley Phillips, Gerard P Brennan, Steven Z George, Maggie E Horn","doi":"10.1177/15563316241309351","DOIUrl":"10.1177/15563316241309351","url":null,"abstract":"<p><p><i>Background:</i> Clinical practice guidelines (CPGs) are developed to synthesize evidence into recommendations for clinical practice. Minimal evidence exists on the evaluation practice of physical therapists in the treatment of patients with neck pain. <i>Purpose</i>: We sought to describe (1) the extent to which clinicians perform the Neck Pain CPG-recommended examination measures and (2) the percentage of patients properly classified. <i>Methods</i>: We retrospectively analyzed the electronic health records of 397 patients with neck pain at an ambulatory care setting in an academic medical center. The frequency of physical therapists' evaluation measures, subjective findings, positive examination results, and the percentage of patients properly classified into impairment-based categories (IBCs) were recorded. Descriptive statistics and χ<sup>2</sup> tests were used to assess patient demographics and compare classification accuracy across IBCs. <i>Results</i>: Of the 397 patients, 56% were classified into an IBC. The most common IBC was neck pain with mobility deficits (24%), followed by neck pain with radiating pain (17%), neck pain with movement coordination impairments (NPMCIs) (8%), and neck pain with headache (6%). Neck pain with movement coordination impairment had the lowest percentage of proper classifications. Classification accuracy was highest when subjective and objective findings were combined and varied between IBCs. <i>Conclusion</i>: Our findings suggest that physical therapists evaluating patients with neck pain may have increased classification accuracy when subjective and objective findings are considered. Decreased classification accuracy was demonstrated in the NPMCI category, highlighting opportunities for further education and research.</p>","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":" ","pages":"15563316241309351"},"PeriodicalIF":1.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11713943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison and Validation of Methods for Restoring Neck Length in Hip Arthroplasty That Can Be Applied for Femoral Neck Fracture. 股骨颈骨折髋关节置换术中恢复颈长方法的比较与验证。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-12-26 DOI: 10.1177/15563316241306109
Alex J Anatone, Rafa Rahman, Tyler J Uppstrom, Jason L Blevins, Peter K Sculco, William M Ricci

Background: Restoring leg length during total hip arthroplasty (THA) for femoral neck fracture is challenging due to the lack of an intact femoral neck on the fractured side. Thus, templating methods typically use size of the intact contralateral hip to estimate length. Common reference points include the distance from the lesser trochanter to the center of the femoral head (LTC) and femoral head diameter (FHD). Objectives: We sought to (1) investigate the LTC:FHD ratio as a preoperative templating method and (2) compare this method with calibrated LTC measurements. Methods: We performed a retrospective review of patients undergoing primary THA between 2021 and 2022 with recorded intraoperative measurements of LTC and FHD at a single academic orthopedic specialty hospital. Preoperative hip X-rays were used to determine the "predicted LTC length" with 2 separate methods: the LTC:FHD ratio yielding the "Ratio Predicted LTC" and the calibrated measurements method yielding the "Calibrated Predicted LTC." These measurements were compared with intraoperative measurements of the LTC length to determine accuracy. Results: Sixty-two hips in 59 patients were studied. The ratio predicted LTC and contralateral ratio predicted LTC length showed no significant difference from the intraoperative LTC length with a strong correlation between the 2 measurements (correlation coefficient = 0.77 and 0.80). The calibrated predicted LTC lengths were significantly different from the intraoperative LTC lengths (mean difference, 3.0 mm; 95% confidence interval [CI] = [2.2, 3.8]). Conclusions: This retrospective review suggests the LTC:FHD ratio multiplied by intraoperative FHD may be an accurate method for restoring anatomic femoral head height in THA (LTCa = [LTCr/FHDr] × FHDa). This method may be useful in hip fracture populations with distorted proximal femoral anatomy.

背景:在股骨颈骨折的全髋关节置换术(THA)中恢复腿长是具有挑战性的,因为骨折侧缺乏完整的股骨颈。因此,模板法通常使用完整对侧髋关节的大小来估计长度。常用的参考点包括小转子到股骨头中心的距离(LTC)和股骨头直径(FHD)。目的:我们试图(1)研究LTC:FHD比率作为术前模板方法,(2)将该方法与校准的LTC测量进行比较。方法:我们对一家学术骨科专科医院在2021年至2022年间接受原发性THA的患者进行了回顾性研究,并记录了术中LTC和FHD的测量。术前髋部x光片通过两种不同的方法确定“预测LTC长度”:LTC:FHD比率产生“比率预测LTC”,校准测量方法产生“校准预测LTC”。将这些测量值与术中LTC长度测量值进行比较,以确定准确性。结果:研究了59例患者的62个髋关节。预测LTC的比值和对侧预测LTC长度的比值与术中LTC长度无显著差异,两者具有较强的相关性(相关系数分别为0.77和0.80)。校正后的预测LTC长度与术中LTC长度有显著差异(平均差3.0 mm;95%置信区间[CI] =[2.2, 3.8])。结论:本回顾性研究提示LTC:FHD比值乘以术中FHD可能是THA术后解剖股骨头高度恢复的准确方法(LTCa = [LTCr/FHDr] × FHDa)。该方法可用于股骨近端解剖畸形的髋部骨折患者。
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引用次数: 0
Design and In Vivo Testing of an Anatomic 3D-Printed Peripheral Nerve Conduit in a Rat Sciatic Nerve Model. 在大鼠坐骨神经模型中设计和体内测试解剖三维打印外周神经导管
IF 1.3 4区 医学 Q3 ORTHOPEDICS Pub Date : 2024-11-22 eCollection Date: 2025-11-01 DOI: 10.1177/15563316241299368
Peter S Chang, Tony Y Lee, David Kneiber, Christopher J Dy, Patrick M Ward, Gregory S Kazarian, John Apostolakos, David M Brogan

Background: Three-dimensional (3D) printer technology has seen a surge in use in medicine, particularly in orthopedics. A recent area of research is its use in peripheral nerve repair, which often requires a graft or conduit to bridge segmental defects. Currently, nerve gaps are bridged using autografts, allografts, or synthetic conduits. Purpose: We sought to improve upon the current design of simple hollow, cylindrical conduits that often result in poor nerve regeneration. Previous attempts were made at reducing axonal dispersion with the use of multichanneled conduits. To our knowledge, none has attempted to mimic and test the anatomical topography of the nerve. Methods: Using serial histology sections, 3D reconstruction software, and computer-aided design, a scaffold was created based on the fascicular topography of a rat sciatic nerve. A 3D printer produced both cylindrical conduits and topography-based scaffolds. These were implanted in 12 Lewis rats: 6 rats with the topographical scaffold and 6 rats with the cylindrical conduit. Each rodent's uninjured contralateral limb was used as a control for comparison of functional and histologic outcomes. Walking track analysis was performed, and the Sciatic Functional Index (SFI) was calculated with the Image J software. After 6 weeks, rats were sacrificed and analyses performed on the regenerated nerve tissue. Primary outcomes measured included nerve (fiber) density, nerve fiber width, total number of nerve fibers, G-ratio (ratio of axon width to total fiber width), and percent debris. Secondary outcomes measured included electrophysiology studies of electromyography (EMG) latency and EMG amplitude and isometric force output by the gastrocnemius and tibialis anterior. Results: There were no differences observed between the cylindrical conduit and topographical scaffold in terms of histological outcomes, muscle force, EMG, or SFI. Conclusion: This study of regeneration of the sciatic nerve in a rat model suggests the feasibility of 3D-printed topographical scaffolds. More research is required to quantify the functional outcomes of this technology for peripheral nerve regeneration.

背景:三维(3D)打印机技术在医学,尤其是骨科领域的应用激增。最近的一个研究领域是其在周围神经修复中的应用,这种修复通常需要移植物或导管来弥合节段性缺损。目前,使用自体移植物、异体移植物或合成导管来弥合神经间隙。目的:我们试图改进目前简单的空心圆柱形导管的设计,这种导管通常会导致神经再生不良。以前曾尝试使用多通道导管来减少轴突分散。据我们所知,还没有人尝试模拟和测试神经的解剖形貌。方法:利用序列组织学切片、三维重建软件和计算机辅助设计,根据大鼠坐骨神经的筋膜地形制作支架。三维打印机可制作圆柱形导管和基于地形的支架。这些支架被植入 12 只路易斯大鼠体内:6 只大鼠植入了地形支架,6 只大鼠植入了圆柱形导管。每只大鼠未受伤的对侧肢体作为对照,用于比较功能和组织学结果。对大鼠进行行走轨迹分析,并使用 Image J 软件计算坐骨神经功能指数(SFI)。6 周后,大鼠被处死,并对再生神经组织进行分析。测量的主要结果包括神经(纤维)密度、神经纤维宽度、神经纤维总数、G 比率(轴突宽度与纤维总宽度之比)和碎屑百分比。次要测量结果包括肌电图(EMG)潜伏期、EMG 振幅以及腓肠肌和胫骨前肌等长肌力输出的电生理学研究。结果:就组织学结果、肌肉力量、肌电图或 SFI 而言,圆柱形导管与地形支架之间没有差异。结论:这项大鼠坐骨神经再生模型研究表明,3D 打印地形支架是可行的。要量化这项技术在周围神经再生方面的功能结果,还需要更多的研究。
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