Pub Date : 2023-01-06DOI: 10.2174/2666082219666230106123926
Xianliang Zheng, Zhihua Xie, Lijuan Huang, Y. Xie, Linlu Peng
The development of mobile Internet technology has brought great changes and convenience in our daily life. However, it has also arisen a series of mental health problems, especially problematic mobile phone use (PMPU). This study aimed to explore the relationship between social exclusion and PMPU among Chinese college students, as well as the mediating role of basic psychological needs satisfaction (BPNS). We recruited a total of 340 participants (mean age 19.71, 44.7% males) from a university in China by convenience sampling. All of them completed the self-report tests of the Social Exclusion Scale, BPNS Scale and Mobile Phone Addiction Index Scale. Data analysis was performed in SPSS 23.0, using the PROCESS macro to examine the mediating effect. Social exclusion was significantly positively correlated with PMPU (r = 0.22, p < 0.001), and significantly negatively correlated with BPNS (r = –0.66, p < 0.001), and BPNS was significantly negatively correlated with PMPU (r = –0.24, p < 0.001). BPNS played a mediating role in the relationship between social exclusion and PMPU. In addition, autonomy needs and competence needs mediated the link of such a relationship, whereas the mediating role of relatedness needs was not significant. Results showed that social exclusion was closely related to PMPU, and social exclusion affected PMPU through BPNS. These findings underline the important role of social relationship and BPNS on adolescents’ PMPU.
{"title":"Social Exclusion and Problematic Mobile Phone Use among Chinese College Students: Mediating Role of Basic Psychological Needs Satisfaction","authors":"Xianliang Zheng, Zhihua Xie, Lijuan Huang, Y. Xie, Linlu Peng","doi":"10.2174/2666082219666230106123926","DOIUrl":"https://doi.org/10.2174/2666082219666230106123926","url":null,"abstract":"\u0000\u0000The development of mobile Internet technology has brought great changes and convenience in our daily life. However, it has also arisen a series of mental health problems, especially problematic mobile phone use (PMPU).\u0000\u0000\u0000\u0000This study aimed to explore the relationship between social exclusion and PMPU among Chinese college students, as well as the mediating role of basic psychological needs satisfaction (BPNS).\u0000\u0000\u0000\u0000We recruited a total of 340 participants (mean age 19.71, 44.7% males) from a university in China by convenience sampling. All of them completed the self-report tests of the Social Exclusion Scale, BPNS Scale and Mobile Phone Addiction Index Scale. Data analysis was performed in SPSS 23.0, using the PROCESS macro to examine the mediating effect.\u0000\u0000\u0000\u0000Social exclusion was significantly positively correlated with PMPU (r = 0.22, p < 0.001), and significantly negatively correlated with BPNS (r = –0.66, p < 0.001), and BPNS was significantly negatively correlated with PMPU (r = –0.24, p < 0.001). BPNS played a mediating role in the relationship between social exclusion and PMPU. In addition, autonomy needs and competence needs mediated the link of such a relationship, whereas the mediating role of relatedness needs was not significant.\u0000\u0000\u0000\u0000Results showed that social exclusion was closely related to PMPU, and social exclusion affected PMPU through BPNS. These findings underline the important role of social relationship and BPNS on adolescents’ PMPU.\u0000","PeriodicalId":36711,"journal":{"name":"Current Psychiatry Research and Reviews","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49305255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-03DOI: 10.2174/2666082219666230103113402
Ayelet Armon-Omer, U. Yatzkar, Eti Amir, S. Tamir
Attention Deficit-Hyperactivity Disorder (ADHD) is one of the most common neuropsychiatric disorders in children. Increasing evidence suggests an association between omega-3 fatty acid and ADHD. We aimed to investigate the effects of 6-month omega-3 fatty acid supplementation on the fatty-acid profile of erythrocytes and on the clinical severity of ADHD symptoms in children. Recruitment included 32 children aged 6-14 years diagnosed with ADHD at the Child and Adolescent Psychiatry Department at Ziv Medical Center, Israel. Intervention included refrigerated omega-3 fatty acid supplementation normalized to body weight. Blood samples were taken at baseline, 3 and 6 months after intervention for quantification of fatty acids from erythrocyte membranes. ADHD symptoms were assessed by parents and teachers according to the ADHD Rating-Scale and the Strengths and Difficulties Questionnaire. ADHD severity was additionally assessed by a psychiatrist according to the Clinical Global Impressions Scale. Supplementation of omega-3 fatty acid in children with ADHD raised their omega-3 index statistically significantly from an average of 4.4% omega-3 index at baseline to 11.6% after 6 months and had beneficial effects on ADHD symptoms, as measured by validated questionnaires and in accordance with a pediatric psychiatrist examination. Our pilot study showed that dietary supplementation of omega-3 fatty acid increased the blood omega-3 index levels and improved ADHD symptoms even at the midpoint of 3 months.
{"title":"Omega-3 fatty acid supplementation improves Attention Deficit-Hyperactivity Disorder symptoms in children","authors":"Ayelet Armon-Omer, U. Yatzkar, Eti Amir, S. Tamir","doi":"10.2174/2666082219666230103113402","DOIUrl":"https://doi.org/10.2174/2666082219666230103113402","url":null,"abstract":"\u0000\u0000Attention Deficit-Hyperactivity Disorder (ADHD) is one of the most common neuropsychiatric disorders in children. Increasing evidence suggests an association between omega-3 fatty acid and ADHD. We aimed to investigate the effects of 6-month omega-3 fatty acid supplementation on the fatty-acid profile of erythrocytes and on the clinical severity of ADHD symptoms in children.\u0000\u0000\u0000\u0000Recruitment included 32 children aged 6-14 years diagnosed with ADHD at the Child and Adolescent Psychiatry Department at Ziv Medical Center, Israel. Intervention included refrigerated omega-3 fatty acid supplementation normalized to body weight. Blood samples were taken at baseline, 3 and 6 months after intervention for quantification of fatty acids from erythrocyte membranes. ADHD symptoms were assessed by parents and teachers according to the ADHD Rating-Scale and the Strengths and Difficulties Questionnaire. ADHD severity was additionally assessed by a psychiatrist according to the Clinical Global Impressions Scale.\u0000\u0000\u0000\u0000Supplementation of omega-3 fatty acid in children with ADHD raised their omega-3 index statistically significantly from an average of 4.4% omega-3 index at baseline to 11.6% after 6 months and had beneficial effects on ADHD symptoms, as measured by validated questionnaires and in accordance with a pediatric psychiatrist examination.\u0000\u0000\u0000\u0000Our pilot study showed that dietary supplementation of omega-3 fatty acid increased the blood omega-3 index levels and improved ADHD symptoms even at the midpoint of 3 months.\u0000","PeriodicalId":36711,"journal":{"name":"Current Psychiatry Research and Reviews","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45306878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-28DOI: 10.2174/2666082219666221228123312
I. Inanli
Lithium is an effective mood stabilizer. In patients with bipolar disorder using long-term lithium, discontinuation of lithium can lead to severe clinical outcomes such as lithium-induced discontinuation refractoriness. We present two clinical cases of lithium-induced discontinuation refractoriness. We present two female patients with a good long-term response to lithium. Both patients did not have a mood episode for many years and had residual symptoms. The first patient discontinued lithium voluntarily, while the second patient discontinued lithium treatment due to impaired thyroid function. Lithium was added to the treatment of both patients, but lithium-induced discontinuation refractoriness developed. It should be kept in mind that it may develop refractoriness to lithium when deciding to discontinue lithium treatment, especially in patients with a good long-term response to lithium.
{"title":"Lithium-induced discontinuation refractoriness: a report of two cases","authors":"I. Inanli","doi":"10.2174/2666082219666221228123312","DOIUrl":"https://doi.org/10.2174/2666082219666221228123312","url":null,"abstract":"\u0000\u0000Lithium is an effective mood stabilizer. In patients with bipolar disorder using long-term lithium, discontinuation of lithium can lead to severe clinical outcomes such as lithium-induced discontinuation refractoriness. We present two clinical cases of lithium-induced discontinuation refractoriness.\u0000\u0000\u0000\u0000We present two female patients with a good long-term response to lithium. Both patients did not have a mood episode for many years and had residual symptoms. The first patient discontinued lithium voluntarily, while the second patient discontinued lithium treatment due to impaired thyroid function. Lithium was added to the treatment of both patients, but lithium-induced discontinuation refractoriness developed.\u0000\u0000\u0000\u0000It should be kept in mind that it may develop refractoriness to lithium when deciding to discontinue lithium treatment, especially in patients with a good long-term response to lithium.\u0000","PeriodicalId":36711,"journal":{"name":"Current Psychiatry Research and Reviews","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48078815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-27DOI: 10.2174/2666082219666221227124013
Ali Khaksour, A. Saeidinia, Ghazale Ghanabri, Adele Akbari, Fateme khazaei, Najme Khani, M. Talebi
Healthcare workers (HCWs) who are directly involved in the management of patients with SARS-CoV-2 infection are at higher risk of psychological disorders. In this study, we evaluated the risk factors related to mental health disorders in HCWs active in the management of the COVID-19 pandemic in Mashhad, Iran. This was a cross-sectional investigation performed between April 2020 and May 2020 at five referral centers in Mashhad, Iran. Patient Health Questionnaire (PHQ-9), 7-item Generalized Anxiety Disorder scale (GAD-7), Insomnia Severity Index (ISI), Impact of Event Scale–Revised (IESR), and VAS (for fear from COVID-19) to assess depression, anxiety, insomnia, distress and fear related to COVID-19 were filled. Risk factors were evaluated by the regression model. Mean ± SD age of participants was 33.84 ± 7.03 years. Most were females (64.2%). Of 360 participants, 252 had some degree of an anxiety disorder (70%), 63.8% had depression, 55.8% had insomnia, and 72.8% had distress. Work experiences (OR: 0.94, 95% CI= 0.901-0.983, P=0.007), exposure to COVID-19 patients (OR: 2.54, 95%CI= 1.37-4.69, P<0.001), and job status (OR: 1.40, 95%CI= 1.19 -1.54, P<0.001) were significant predictors of anxiety. Age (OR: 1.15, 95% CI= 1.05-1.27, P=0.002), exposure to COVID-19 patients (OR: 1.95, 95%CI= 1.04-3.64, P=0.037), work experience (OR: 0.86, 95%CI= 0.78-0.93, P<0.001), having children (OR: 0.58, 95%CI= 0.39- 0.87, P=0.008), and being infected with COVID-19 (OR: 9.95, 95%CI= 1.92-51.64, P<0.001) were the significant independent factors for depression in participants. COVID-19 could significantly affect HCWs mental health status, specifically depression. By targeting these predictors, health policymakers can reduce the burden of psychological disorders in HCWs.
{"title":"Mental Health Disorders in Healthcare Workers Exposed to COVID-19, Mashhad, Iran: A Cross-sectional Study","authors":"Ali Khaksour, A. Saeidinia, Ghazale Ghanabri, Adele Akbari, Fateme khazaei, Najme Khani, M. Talebi","doi":"10.2174/2666082219666221227124013","DOIUrl":"https://doi.org/10.2174/2666082219666221227124013","url":null,"abstract":"\u0000\u0000Healthcare workers (HCWs) who are directly involved in the management of patients with SARS-CoV-2 infection are at higher risk of psychological disorders.\u0000\u0000\u0000\u0000In this study, we evaluated the risk factors related to mental health disorders in HCWs active in the management of the COVID-19 pandemic in Mashhad, Iran.\u0000\u0000\u0000\u0000This was a cross-sectional investigation performed between April 2020 and May 2020 at five referral centers in Mashhad, Iran. Patient Health Questionnaire (PHQ-9), 7-item Generalized Anxiety Disorder scale (GAD-7), Insomnia Severity Index (ISI), Impact of Event Scale–Revised (IESR), and VAS (for fear from COVID-19) to assess depression, anxiety, insomnia, distress and fear related to COVID-19 were filled. Risk factors were evaluated by the regression model.\u0000\u0000\u0000\u0000Mean ± SD age of participants was 33.84 ± 7.03 years. Most were females (64.2%). Of 360 participants, 252 had some degree of an anxiety disorder (70%), 63.8% had depression, 55.8% had insomnia, and 72.8% had distress. Work experiences (OR: 0.94, 95% CI= 0.901-0.983, P=0.007), exposure to COVID-19 patients (OR: 2.54, 95%CI= 1.37-4.69, P<0.001), and job status (OR: 1.40, 95%CI= 1.19 -1.54, P<0.001) were significant predictors of anxiety. Age (OR: 1.15, 95% CI= 1.05-1.27, P=0.002), exposure to COVID-19 patients (OR: 1.95, 95%CI= 1.04-3.64, P=0.037), work experience (OR: 0.86, 95%CI= 0.78-0.93, P<0.001), having children (OR: 0.58, 95%CI= 0.39- 0.87, P=0.008), and being infected with COVID-19 (OR: 9.95, 95%CI= 1.92-51.64, P<0.001) were the significant independent factors for depression in participants.\u0000\u0000\u0000\u0000COVID-19 could significantly affect HCWs mental health status, specifically depression. By targeting these predictors, health policymakers can reduce the burden of psychological disorders in HCWs.\u0000","PeriodicalId":36711,"journal":{"name":"Current Psychiatry Research and Reviews","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49059839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-26DOI: 10.2174/2666082219666221226151805
M. Zinchuk, E. Pashnin, G. Kustov, S. Popova, N. Voinova, A. Gersamia, A. Yakovlev, A. Guekht
To investigate the level of anxiety as well as attitude toward disease and mitigation strategies in people with non-psychotic mental disorders and healthy controls. The new coronavirus disease (COVID-19) pandemic resulted in an unprecedented morbidity and mortality and economic consequences worldwide. Response to pandemic required an urgent and radical change in the medical care delivery with a focus on infectious disease, which is uncommon for most developed countries. Implemented changes led to reduced psychiatric (especially inpatient) care utilization. To investigate the level of anxiety as well as attitude toward disease and mitigation strategies in people with non-psychotic mental disorders and healthy controls. A case-control study (1:4) was conducted during a self-isolation regimen in Moscow. Cases were adult patients with NPMD consequently admitted to the Moscow Research and Clinical Center for Neuropsychiatry. Sex and age-matched controls (individuals who have never sought psychiatric help) were selected from a cohort of 7498 Moscow residents who participated in a largecross-sectional survey delivered via social networks and popular Russian web platforms. The level of the trait but not state anxiety was higher in people with NPMD. People with mental disorders were significantly more often concerned about the negative impact of the COVID-19 pandemic on their lives, were more likely to be confident that they would contract the coronavirus and their disease would be severe, showed suboptimal adherence to mitigation strategies, were dissatisfied with the amount of information they received about the COVID-19 and were more concerned about becoming a victim of domestic violence. People with NPMD have higher level of trait anxiety and are prompted to develop the constellation of maladaptive beliefs toward a pandemic. These beliefs along with the lack of reliable information on coronavirus infection can lead to misunderstanding and disregard of sanitary and self-isolation recommendations. Educational programs and vaccination campaigns should be sensitive to these features of people with NPMD. No
{"title":"Worriers of the pandemic: How people with mental disorders cope with COVID-19 restrictions","authors":"M. Zinchuk, E. Pashnin, G. Kustov, S. Popova, N. Voinova, A. Gersamia, A. Yakovlev, A. Guekht","doi":"10.2174/2666082219666221226151805","DOIUrl":"https://doi.org/10.2174/2666082219666221226151805","url":null,"abstract":"\u0000\u0000To investigate the level of anxiety as well as attitude toward disease and mitigation strategies in people with non-psychotic mental disorders and healthy controls.\u0000\u0000\u0000\u0000The new coronavirus disease (COVID-19) pandemic resulted in an unprecedented morbidity and mortality and economic consequences worldwide. Response to pandemic required an urgent and radical change in the medical care delivery with a focus on infectious disease, which is uncommon for most developed countries. Implemented changes led to reduced psychiatric (especially inpatient) care utilization.\u0000\u0000\u0000\u0000To investigate the level of anxiety as well as attitude toward disease and mitigation strategies in people with non-psychotic mental disorders and healthy controls.\u0000\u0000\u0000\u0000A case-control study (1:4) was conducted during a self-isolation regimen in Moscow. Cases were adult patients with NPMD consequently admitted to the Moscow Research and Clinical Center for Neuropsychiatry. Sex and age-matched controls (individuals who have never sought psychiatric help) were selected from a cohort of 7498 Moscow residents who participated in a largecross-sectional survey delivered via social networks and popular Russian web platforms.\u0000\u0000\u0000\u0000The level of the trait but not state anxiety was higher in people with NPMD. People with mental disorders were significantly more often concerned about the negative impact of the COVID-19 pandemic on their lives, were more likely to be confident that they would contract the coronavirus and their disease would be severe, showed suboptimal adherence to mitigation strategies, were dissatisfied with the amount of information they received about the COVID-19 and were more concerned about becoming a victim of domestic violence.\u0000\u0000\u0000\u0000People with NPMD have higher level of trait anxiety and are prompted to develop the constellation of maladaptive beliefs toward a pandemic. These beliefs along with the lack of reliable information on coronavirus infection can lead to misunderstanding and disregard of sanitary and self-isolation recommendations. Educational programs and vaccination campaigns should be sensitive to these features of people with NPMD.\u0000\u0000\u0000\u0000No\u0000","PeriodicalId":36711,"journal":{"name":"Current Psychiatry Research and Reviews","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45015284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-06DOI: 10.2174/2666082219666221206112951
E. Darin
Organic disorder remains one of the most pressing issues in practical psychiatry, especially a disorder dominated by persistent or recurrent delusions. The difficulty for practitioners is often due to the older age of patients and the burden of concomitant therapeutic diseases. Modern and potentially promising pharmacological drugs developed in recent years include partial agonists of D2 and D3 receptors. Currently, there are insufficient publications of studies on Cariprazine use in various disorders that are not associated with endogenous pathology. The author presented the results of the patient’s clinical examination with a complex of psychodiagnostic techniques, instrumental research methods, observation data in the department, and an analysis of the patient’s medical history. The paper describes the experience of treating a patient with the latest generation antipsychotic drug Cariprazine. The author presents a case report on Cariprazine therapy in a 71-year-old female patient with a persistent organic delusional disorder with concomitant severe somatic illness. Cariprazine showed good efficacy in this case. Delusional symptoms were significantly reduced, and the author noted a reduction in negative symptoms. Mild side effects of the drug quickly resolved in the course of treatment. The key point is that the description of this case may be relevant to justify the need for further clinical studies on Cariprazine. Further clinical studies of the drug in the treatment of various mental pathologies may be in demand by specialists around the world.
{"title":"Case Report: The Experience Using Cariprazine in Organic Delusional Disorder in an Elderly Patient with Concomitant Somatic Pathology, Brief Report","authors":"E. Darin","doi":"10.2174/2666082219666221206112951","DOIUrl":"https://doi.org/10.2174/2666082219666221206112951","url":null,"abstract":"\u0000\u0000Organic disorder remains one of the most pressing issues in practical psychiatry, especially a disorder dominated by persistent or recurrent delusions. The difficulty for practitioners is often due to the older age of patients and the burden of concomitant therapeutic diseases. Modern and potentially promising pharmacological drugs developed in recent years include partial agonists of D2 and D3 receptors. Currently, there are insufficient publications of studies on Cariprazine use in various disorders that are not associated with endogenous pathology.\u0000\u0000\u0000\u0000The author presented the results of the patient’s clinical examination with a complex of psychodiagnostic techniques, instrumental research methods, observation data in the department, and an analysis of the patient’s medical history. The paper describes the experience of treating a patient with the latest generation antipsychotic drug Cariprazine.\u0000\u0000\u0000\u0000The author presents a case report on Cariprazine therapy in a 71-year-old female patient with a persistent organic delusional disorder with concomitant severe somatic illness.\u0000\u0000\u0000\u0000Cariprazine showed good efficacy in this case. Delusional symptoms were significantly reduced, and the author noted a reduction in negative symptoms. Mild side effects of the drug quickly resolved in the course of treatment. \u0000The key point is that the description of this case may be relevant to justify the need for further clinical studies on Cariprazine. Further clinical studies of the drug in the treatment of various mental pathologies may be in demand by specialists around the world.\u0000","PeriodicalId":36711,"journal":{"name":"Current Psychiatry Research and Reviews","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48618885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-14DOI: 10.2174/2666082219666221114114738
Kedar S Prabhavalkar, Mikhil Santosh Kore
Depression, or major depressive disorder, is a mental illness that significantly affects psychosocial functioning and reduces the quality of one’s life. The annual incidence of depression throughout the globe is around 6%. The disorder should be diagnosed at a particular stage for the treatment to be designed. Biomarkers can help to do so with objective pieces of evidence. Various biomarkers like Imaging biomarkers, Molecular biomarkers, Transcriptomic biomarkers, Genetic biomarkers, Neuroendocrine, and Inflammatory biomarkers can be used to diagnose depression. The use of digital sensors has also been reported recently for the determination of depression. This review summarizes various biomarkers to diagnose depression. Further recent updates and related clinical trials are included.
{"title":"Biomarkers for the diagnosis of depression: Recent updates","authors":"Kedar S Prabhavalkar, Mikhil Santosh Kore","doi":"10.2174/2666082219666221114114738","DOIUrl":"https://doi.org/10.2174/2666082219666221114114738","url":null,"abstract":"\u0000\u0000Depression, or major depressive disorder, is a mental illness that significantly affects psychosocial functioning and reduces the quality of one’s life. The annual incidence of depression throughout the globe is around 6%. The disorder should be diagnosed at a particular stage for the treatment to be designed. Biomarkers can help to do so with objective pieces of evidence. Various biomarkers like Imaging biomarkers, Molecular biomarkers, Transcriptomic biomarkers, Genetic biomarkers, Neuroendocrine, and Inflammatory biomarkers can be used to diagnose depression. The use of digital sensors has also been reported recently for the determination of depression. This review summarizes various biomarkers to diagnose depression. Further recent updates and related clinical trials are included.\u0000","PeriodicalId":36711,"journal":{"name":"Current Psychiatry Research and Reviews","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47631862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-28DOI: 10.2174/2666082219666221028102903
U. Barahmand, Ezra Hermann, Aditi Rai, Amisha Tewari, S. Kopyto, Kayla Castellanos
This study aims to examine mechanisms that may account for the comorbidity between social anxiety and depression. We hypothesized that maladaptive metacognitions and anhedonia would serially mediate the link between social anxiety and depression. We tested this notion by collecting data from 208 international, English speaking participants ranging from the ages of 18 to 65 years old using the Social Interaction Anxiety Scale (SIAS), Self-Assessment Anhedonia Scale (SAAS), Patient’s Health Questionnaire-9 (PHQ-9), and Metacognition Questionnaire (MCQ-30). The results show a significant serial mediation effect from social anxiety via beliefs about uncontrollability and danger and anhedonia to depression, with the pathway from social anxiety via reduced beliefs in cognitive confidence and anhedonia to depression not being significant. Furthermore, a direct path from social anxiety to depression was also significant. Findings provide support for both the tripartite model and the self-regulatory executive function model of anxiety and depression. While the findings imply the contributions of other mediating variables, they also indicate that metacognitive therapy with additional focus on anhedonia could be effective in preventing the development of depression.
{"title":"Linking Social Anxiety and Depression: The Role of Metacognitive Beliefs and Anhedonia","authors":"U. Barahmand, Ezra Hermann, Aditi Rai, Amisha Tewari, S. Kopyto, Kayla Castellanos","doi":"10.2174/2666082219666221028102903","DOIUrl":"https://doi.org/10.2174/2666082219666221028102903","url":null,"abstract":"\u0000\u0000This study aims to examine mechanisms that may account for the comorbidity between social anxiety and depression.\u0000\u0000\u0000\u0000We hypothesized that maladaptive metacognitions and anhedonia would serially mediate the link between social anxiety and depression.\u0000\u0000\u0000\u0000We tested this notion by collecting data from 208 international, English speaking participants ranging from the ages of 18 to 65 years old using the Social Interaction Anxiety Scale (SIAS), Self-Assessment Anhedonia Scale (SAAS), Patient’s Health Questionnaire-9 (PHQ-9), and Metacognition Questionnaire (MCQ-30).\u0000\u0000\u0000\u0000The results show a significant serial mediation effect from social anxiety via beliefs about uncontrollability and danger and anhedonia to depression, with the pathway from social anxiety via reduced beliefs in cognitive confidence and anhedonia to depression not being significant. Furthermore, a direct path from social anxiety to depression was also significant.\u0000\u0000\u0000\u0000Findings provide support for both the tripartite model and the self-regulatory executive function model of anxiety and depression. While the findings imply the contributions of other mediating variables, they also indicate that metacognitive therapy with additional focus on anhedonia could be effective in preventing the development of depression.\u0000","PeriodicalId":36711,"journal":{"name":"Current Psychiatry Research and Reviews","volume":"39 2","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41283891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-29DOI: 10.2174/2666082218666220929113437
Afsaneh Aminpour, Shiva Soraya, Hamidreza Ahmad khaniha
Substance use disorders are highly prevalent among psychotic patients and are associated with poorer clinical outcomes. The study aimed to investigate the prevalence of psychotic disorders in substance users and the epidemiological features of this population. In a cross-sectional study, we investigated 455 outpatient and inpatient participants with SUD referred to the Iran psychiatric hospital from April 2020 to March 2021. All participants were substance users, referred to Iran psychiatric center to follow up on their comorbidities and psychiatric disorders. The Structured Clinical Interview for DSM-5 (SCID) was used for psychotic disorders and substance use disorder diagnoses. Finally, gathered data were analyzed by SPSS-25. 455 patients were involved in the study. The mean age was 34.66 years, of which 89.7% were men. The most common main substances include methamphetamine (39.1%) and heroin (27%). The Prevalence of psychotic disorder was 36.7%, and the most common type was substance-induced psychotic disorder (26.4%) and schizophrenia (8.4%). There was a significant association between methamphetamine and opium use and the presence of substance-induced psychotic disorder and schizophrenia, respectively (p˂ 0.001). The most common type of substance use was methamphetamine and the most common type of psychotic disorder was substance-induced psychotic disorder. There was a significant association between methamphetamine and opium use and the presence of substance-induced psychotic disorder and schizophrenia, respectively. It should be noted that this was a sample of individuals hospitalized for substance abuse. It was not a general population sample and is very biased toward substance use.
{"title":"Prevalence of comorbidities of psychotic disorders in patients with substance use disorders in Iran Psychiatric Hospital in Tehran, Iran","authors":"Afsaneh Aminpour, Shiva Soraya, Hamidreza Ahmad khaniha","doi":"10.2174/2666082218666220929113437","DOIUrl":"https://doi.org/10.2174/2666082218666220929113437","url":null,"abstract":"\u0000\u0000Substance use disorders are highly prevalent among psychotic patients and are associated with poorer clinical outcomes.\u0000\u0000\u0000\u0000The study aimed to investigate the prevalence of psychotic disorders in substance users and the epidemiological features of this population.\u0000\u0000\u0000\u0000In a cross-sectional study, we investigated 455 outpatient and inpatient participants with SUD referred to the Iran psychiatric hospital from April 2020 to March 2021. All participants were substance users, referred to Iran psychiatric center to follow up on their comorbidities and psychiatric disorders. The Structured Clinical Interview for DSM-5 (SCID) was used for psychotic disorders and substance use disorder diagnoses. Finally, gathered data were analyzed by SPSS-25.\u0000\u0000\u0000\u0000455 patients were involved in the study. The mean age was 34.66 years, of which 89.7% were men. The most common main substances include methamphetamine (39.1%) and heroin (27%). The Prevalence of psychotic disorder was 36.7%, and the most common type was substance-induced psychotic disorder (26.4%) and schizophrenia (8.4%). There was a significant association between methamphetamine and opium use and the presence of substance-induced psychotic disorder and schizophrenia, respectively (p˂ 0.001).\u0000\u0000\u0000\u0000The most common type of substance use was methamphetamine and the most common type of psychotic disorder was substance-induced psychotic disorder. There was a significant association between methamphetamine and opium use and the presence of substance-induced psychotic disorder and schizophrenia, respectively. It should be noted that this was a sample of individuals hospitalized for substance abuse. It was not a general population sample and is very biased toward substance use.\u0000","PeriodicalId":36711,"journal":{"name":"Current Psychiatry Research and Reviews","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46731145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-22DOI: 10.2174/2666082218666220922101408
U. Bhaumik
The coronavirus pandemic of 2019 has resulted in extensive social regulations and affected many aspects of life. It has led to significant stress and adversely impacted the mental health across the globe. The virus has been found to directly increase neuropsychiatric sequelae in those affected. Various other psychosocial factors have also increased the incidence and prevalence of mental health problems worldwide. There was a need for a ramp-up of psychiatric services to support individuals in such a situation. Even after the pandemic, there is a need for improving access to mental health services for the mentally ill as well as those affected by the regulations brought about to tackle the pandemic. Tele psychiatric services are in place throughout the world in different forms and they are the answer to bridging the mental health gap during and in the aftermath of the pandemic. Hence, it is important to continue developing and enhance tele psychiatric services in different countries for supporting and treating individuals affected by the pandemic.
{"title":"Mental health needs in COVID and post-COVID era-how far can Telepsychiatry address the challenges?","authors":"U. Bhaumik","doi":"10.2174/2666082218666220922101408","DOIUrl":"https://doi.org/10.2174/2666082218666220922101408","url":null,"abstract":"\u0000\u0000The coronavirus pandemic of 2019 has resulted in extensive social regulations and affected many aspects of life. It has led to significant stress and adversely impacted the mental health across the globe. The virus has been found to directly increase neuropsychiatric sequelae in those affected. Various other psychosocial factors have also increased the incidence and prevalence of mental health problems worldwide. There was a need for a ramp-up of psychiatric services to support individuals in such a situation. Even after the pandemic, there is a need for improving access to mental health services for the mentally ill as well as those affected by the regulations brought about to tackle the pandemic. Tele psychiatric services are in place throughout the world in different forms and they are the answer to bridging the mental health gap during and in the aftermath of the pandemic. Hence, it is important to continue developing and enhance tele psychiatric services in different countries for supporting and treating individuals affected by the pandemic.\u0000","PeriodicalId":36711,"journal":{"name":"Current Psychiatry Research and Reviews","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44902672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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