Aim: In this study, we aimed to evaluated whether there is an association between the biochemistry parameters obtained from the first blood test after hospitalization of COVID 19 patients and the prognosis and severity of the disease. Thus, we planned to identify patients with a severe course at an early stage and to help physicians determine the appropriate treatment. Material and Method: The study included 106 COVID 19 patients confirmed by RT-PCR. Patients were categorized into two groups: those admitted to the hospital ward and discharged with recovery (mild cases) and those admitted directly or eventually to the intensive care unit (severe cases). Biochemical parameters of the groups were compared with the Mann Whitney-U Test, as none of the compared parameters fit the normal distribution. Results: There was no statistically significant difference between the male-female numbers and ages of the two groups. Statistically significant differences were observed in the length of hospital stay, procalcitonin, hs-troponin I, ferritin, glucose, urea, creatinine, calcium, direct bilirubin, AST, LDH and CRP values (p<0,05). However, no significant difference was found in sodium, potassium, chloride, total bilirubin and ALT tests. Conclusion: The results show that some biochemistry parameters may be used to predict the prognosis of the disease. In particular, procalcitonin, hs troponin I, LDH and CRP values seem to be moderate biomarkers of the prognosis of the disease.
{"title":"Biochemical parameters and relation to disease severity in COVID-19 patients","authors":"","doi":"10.51271/kmj-0026","DOIUrl":"https://doi.org/10.51271/kmj-0026","url":null,"abstract":"Aim: In this study, we aimed to evaluated whether there is an association between the biochemistry parameters obtained from the first blood test after hospitalization of COVID 19 patients and the prognosis and severity of the disease. Thus, we planned to identify patients with a severe course at an early stage and to help physicians determine the appropriate treatment. \u0000Material and Method: The study included 106 COVID 19 patients confirmed by RT-PCR. Patients were categorized into two groups: those admitted to the hospital ward and discharged with recovery (mild cases) and those admitted directly or eventually to the intensive care unit (severe cases). Biochemical parameters of the groups were compared with the Mann Whitney-U Test, as none of the compared parameters fit the normal distribution. \u0000Results: There was no statistically significant difference between the male-female numbers and ages of the two groups. Statistically significant differences were observed in the length of hospital stay, procalcitonin, hs-troponin I, ferritin, glucose, urea, creatinine, calcium, direct bilirubin, AST, LDH and CRP values (p<0,05). However, no significant difference was found in sodium, potassium, chloride, total bilirubin and ALT tests. \u0000Conclusion: The results show that some biochemistry parameters may be used to predict the prognosis of the disease. In particular, procalcitonin, hs troponin I, LDH and CRP values seem to be moderate biomarkers of the prognosis of the disease.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126696022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Metabolic syndrome (MS) is a significant public health problem and has the potential to increase the risk of developing cardiovascular diseases (CVD), the risk of type 2 Diabetes Mellitus (T2DM), the risk of stroke and the risk of a heart attack. MS has recently been considered an inflammatory disease. Lipoxins (LXs) are, on the other hand, bioactive lipid molecules synthesized from arachidonic acid (AA) and show potent anti-inflammatory and pro-resolving activities in vivo and in vitro conditions. In this study, we aimed to evaluate serum levels of LXA4 in MS patients and explore the relationship of serum LXA4 levels with MS components [waist circumference, blood pressure, serum high-density lipoprotein (HDL), and triglyceride (TG) levels]. Material and Method: In this study, the sample was composed of 39 patients diagnosed with MS and 32 healthy age- and sex-matched individuals. We measured serum LXA4 levels adopting the enzyme-linked immunosorbent assay (ELISA) method with “Human Lipoxin A4 ELISA Kit”. While collecting the blood samples from the subjects, we noted their ages, sex, physical examination findings, and anthropometric measurements [height, weight, waist circumference, and body mass index (BMI)]. Additionally, we obtained their serum TG, low-density lipoprotein (LDL), HDL, glucose, and cholesterol levels. Results: While we could not find any significant differences between the groups by age and sex (p>0.05), the groups significantly differed by weight, waist circumference, BMI, systolic blood pressure, diastolic blood pressure, TG, HDL, and FBG (p<0.05 for TG; p<0.001 for others). Moreover, serum levels of LXA4 significantly differed between the groups (p<0.05). Within-group comparisons showed that while serum levels of LXA4 significantly differed between male subjects (p=0.01), it was not the case for females (p>0.05). In both groups, there were negative correlations between serum LXA4 levels and waist circumference (r=-0.368 p=0.02). Yet, we found such an association only among male patients (r=-0.516 p=0.02). Conclusion: Overall, we found serum LXA4 levels to be significantly low in MS patients (p<0.05). Yet, it still needs to be elucidated whether this impairment is a cause or a result of MS. Finally, we discovered this impairment and its significant correlations with some MS parameters to be only in male patients, suggesting that serum LXA4 levels may vary by sex in MS patients.
{"title":"An investigation of the association between lipoxin A4 levels and metabolic syndrome parameters in patients with metabolic syndrome","authors":"","doi":"10.51271/kmj-0023","DOIUrl":"https://doi.org/10.51271/kmj-0023","url":null,"abstract":"Aim: Metabolic syndrome (MS) is a significant public health problem and has the potential to increase the risk of developing cardiovascular diseases (CVD), the risk of type 2 Diabetes Mellitus (T2DM), the risk of stroke and the risk of a heart attack. MS has recently been considered an inflammatory disease. Lipoxins (LXs) are, on the other hand, bioactive lipid molecules synthesized from arachidonic acid (AA) and show potent anti-inflammatory and pro-resolving activities in vivo and in vitro conditions. In this study, we aimed to evaluate serum levels of LXA4 in MS patients and explore the relationship of serum LXA4 levels with MS components [waist circumference, blood pressure, serum high-density lipoprotein (HDL), and triglyceride (TG) levels]. \u0000Material and Method: In this study, the sample was composed of 39 patients diagnosed with MS and 32 healthy age- and sex-matched individuals. We measured serum LXA4 levels adopting the enzyme-linked immunosorbent assay (ELISA) method with “Human Lipoxin A4 ELISA Kit”. While collecting the blood samples from the subjects, we noted their ages, sex, physical examination findings, and anthropometric measurements [height, weight, waist circumference, and body mass index (BMI)]. Additionally, we obtained their serum TG, low-density lipoprotein (LDL), HDL, glucose, and cholesterol levels. \u0000Results: While we could not find any significant differences between the groups by age and sex (p>0.05), the groups significantly differed by weight, waist circumference, BMI, systolic blood pressure, diastolic blood pressure, TG, HDL, and FBG (p<0.05 for TG; p<0.001 for others). Moreover, serum levels of LXA4 significantly differed between the groups (p<0.05). Within-group comparisons showed that while serum levels of LXA4 significantly differed between male subjects (p=0.01), it was not the case for females (p>0.05). In both groups, there were negative correlations between serum LXA4 levels and waist circumference (r=-0.368 p=0.02). Yet, we found such an association only among male patients (r=-0.516 p=0.02). \u0000Conclusion: Overall, we found serum LXA4 levels to be significantly low in MS patients (p<0.05). Yet, it still needs to be elucidated whether this impairment is a cause or a result of MS. Finally, we discovered this impairment and its significant correlations with some MS parameters to be only in male patients, suggesting that serum LXA4 levels may vary by sex in MS patients.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134324077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nesfatin-1is first described in 2006 as an anorectic peptide and regulate food intake. In following years, the studies demonstrated the presence of nesfatin-1 in central and various peripheral tissues. Thus, nesfatin-1 popularity increasing widely in clinical medicine, especially in cardiology, neurology, reproduction, metabolic disorders, psychiatric disorders, gastrointestinal system. Today, the main point concerning nesfatin-1 action in body organ and systems is concentrate its biological signals effects. Thus the increasing knowledge in these area will be highlighted for future studies especially in serious health problem all over the world population.
{"title":"The essential role of nesfatin-1 as a biological signal on the body systems","authors":"","doi":"10.51271/kmj-0028","DOIUrl":"https://doi.org/10.51271/kmj-0028","url":null,"abstract":"Nesfatin-1is first described in 2006 as an anorectic peptide and regulate food intake. In following years, the studies demonstrated the presence of nesfatin-1 in central and various peripheral tissues. Thus, nesfatin-1 popularity increasing widely in clinical medicine, especially in cardiology, neurology, reproduction, metabolic disorders, psychiatric disorders, gastrointestinal system. Today, the main point concerning nesfatin-1 action in body organ and systems is concentrate its biological signals effects. Thus the increasing knowledge in these area will be highlighted for future studies especially in serious health problem all over the world population.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122476378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Today, many hypotheses have been proposed in the pathogenesis of migraine. The inflammatory hypothesis is one of them. The immature granulocyte count (IGC) is also an inflammatory parameter which importance has been understood recently. There are no studies evaluating IGC in migraine. The aim of the study to investigate the levels of IGC and other hematological inflammatory parameters in migraine. Material and Method: Materials and Methods: Forty-eight patients diagnosed with migraine who applied to Kastamonu Training and Research Hospital Neurology outpatient clinic between 07.01.2020 and 10.01.2021 were included in the study. 42 people with similar age and gender distribution were included for the control group. Data on laboratory tests, age and gender of patients were obtained from the hospital Laboratory Information System (LIS). CBC parameters of the patients at the first admission and before any treatment, calculated with an automated hematological analyzer (XN-1000-Hematology-analyzer-Sysmex Corporation, Japan) were analyzed. Using Complete Blood Count (CBC) data, neutrophil count (NEUT#), neutrophil percentage (NEUT%), lymphocyte percentage (LYMPH%), and IGC were recorded. Neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and systemic immune inflammation index (SII) values were calculated with the formula. Results: In our study, NLR and IGC was significantly higher than the healthy control group (p=0.002, p=0.025). PLR was also found to be high, but it was not statistically significant (p=0.063). Conclusion: The significantly higher NLR and IGC levels in migraine patients compared to the healthy controls support the role of inflammation in etiopathogenesis.
{"title":"Immature granulocyte and other hematological inflammatory parameters in patients with migraine headache","authors":"","doi":"10.51271/kmj-0025","DOIUrl":"https://doi.org/10.51271/kmj-0025","url":null,"abstract":"Background: Today, many hypotheses have been proposed in the pathogenesis of migraine. The inflammatory hypothesis is one of them. The immature granulocyte count (IGC) is also an inflammatory parameter which importance has been understood recently. There are no studies evaluating IGC in migraine. The aim of the study to investigate the levels of IGC and other hematological inflammatory parameters in migraine. \u0000Material and Method: Materials and Methods: Forty-eight patients diagnosed with migraine who applied to Kastamonu Training and Research Hospital Neurology outpatient clinic between 07.01.2020 and 10.01.2021 were included in the study. 42 people with similar age and gender distribution were included for the control group. Data on laboratory tests, age and gender of patients were obtained from the hospital Laboratory Information System (LIS). CBC parameters of the patients at the first admission and before any treatment, calculated with an automated hematological analyzer (XN-1000-Hematology-analyzer-Sysmex Corporation, Japan) were analyzed. Using Complete Blood Count (CBC) data, neutrophil count (NEUT#), neutrophil percentage (NEUT%), lymphocyte percentage (LYMPH%), and IGC were recorded. Neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and systemic immune inflammation index (SII) values were calculated with the formula. \u0000Results: In our study, NLR and IGC was significantly higher than the healthy control group (p=0.002, p=0.025). PLR was also found to be high, but it was not statistically significant (p=0.063). \u0000Conclusion: The significantly higher NLR and IGC levels in migraine patients compared to the healthy controls support the role of inflammation in etiopathogenesis.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116384066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aimed to evaluate the relationship between mean platelet volume and red blood cell distribution width, recurrent epistaxis in children. Material and Method:This study was conducted with 60 pediatric patients who applied to our clinic between complaint of epistaxis. The control group consisted of 60 pediatric patients with similar number of age and gender characteristics as the study group. mean platelet volume (MPV) and red cell distribution width (RDW) values measured routinely in the complete blood count (CBC) were investigated Results: Mean RDW value was founded 11.98±0.75% in patients with epistaxis and 12.44±0.78% in the control group. Since the p-value calculated according to these data was found to be 0.02, the difference was found to be statistically significant. The MPV value was 6.65±1.31 femtoliter in patients with epistaxis and 6.41±1.22 femtoliter in the control group. The difference was not statistically significant since the p-value was higher than 0.05. Conclusion: It is thought that the high values of RDW and MPV, which are among the parameters measured in complete blood count, may be associated with the increase in thrombotic activity. It is also observed that MPV and RDW values are high in cerebrovascular cases and coronary artery diseases. The low RDW value in patients who with recurrent epistaxis gives rise to thought that this value may not be a result of bleeding, but a cause.
{"title":"Mean platellet volume and red cell distribution width values in children with recurrent epistaxis","authors":"","doi":"10.51271/kmj-0022","DOIUrl":"https://doi.org/10.51271/kmj-0022","url":null,"abstract":"Objective: This study aimed to evaluate the relationship between mean platelet volume and red blood cell distribution width, recurrent epistaxis in children. \u0000Material and Method:This study was conducted with 60 pediatric patients who applied to our clinic between complaint of epistaxis. The control group consisted of 60 pediatric patients with similar number of age and gender characteristics as the study group. mean platelet volume (MPV) and red cell distribution width (RDW) values measured routinely in the complete blood count (CBC) were investigated \u0000Results: Mean RDW value was founded 11.98±0.75% in patients with epistaxis and 12.44±0.78% in the control group. Since the p-value calculated according to these data was found to be 0.02, the difference was found to be statistically significant. The MPV value was 6.65±1.31 femtoliter in patients with epistaxis and 6.41±1.22 femtoliter in the control group. The difference was not statistically significant since the p-value was higher than 0.05. \u0000Conclusion: It is thought that the high values of RDW and MPV, which are among the parameters measured in complete blood count, may be associated with the increase in thrombotic activity. It is also observed that MPV and RDW values are high in cerebrovascular cases and coronary artery diseases. The low RDW value in patients who with recurrent epistaxis gives rise to thought that this value may not be a result of bleeding, but a cause.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121675017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: Hypertensive conditions are situations that require immediate intervention in emergency services. Captopril is one of the most commonly used drugs in patients presenting to emergency departments with high blood pressure. In this study; we aimed to find an answer to the question of whether orally administered olmesartan could be an alternative to captopril in urgent hypertensive situations. Material and Method: In this study, blood pressure measurements were made after a 5-minute rest period in patients who presented to the emergency department of our hospital with the diagnosis of hypertension. Patients with a blood pressure of 180/100 mmHg and above and no signs of end-organ damage were followed up. Forty patients were given sublingual captopril 25 mg, and the other 40 patients were given 40 mg of olmesartan, and they were allowed to swallow the drug with some water. Afterward, the patients were followed for 3 hours (with blood pressure and pulse measurements), and their blood pressure was measured and recorded at five-minute intervals. Results: The mean age of the patients receiving captopril was 60.70±11.43 years, and the mean age of the patients receiving olmesartan was 57.02±13.86 years. Of the patients receiving captopril, 19 (57.5%) were male, 21 (52.5%) were female, 17 (42.5%) of the patients receiving olmesartan were male and 23 (57.5%) were female. In this study, patients treated with captopril and olmesartan were monitored for 3 hours and the differences between them in pulse and blood pressure measurements were evaluated. When the systolic blood pressures were compared, the difference at the tenth minute was significant, but the difference between the other minutes was not significant. Differences in diastolic blood pressure and heart rate were not significant. Conclusion: Oral administration of olmesartan in emergency hypertensive patients may be an alternative to captopril due to its effectiveness in reducing mortality and morbidity.
{"title":"Comparison of the effectiveness of captopril and olmesartan in hypertensive patients","authors":"","doi":"10.51271/kmj-0024","DOIUrl":"https://doi.org/10.51271/kmj-0024","url":null,"abstract":"Purpose: Hypertensive conditions are situations that require immediate intervention in emergency services. Captopril is one of the most commonly used drugs in patients presenting to emergency departments with high blood pressure. In this study; we aimed to find an answer to the question of whether orally administered olmesartan could be an alternative to captopril in urgent hypertensive situations. \u0000Material and Method: In this study, blood pressure measurements were made after a 5-minute rest period in patients who presented to the emergency department of our hospital with the diagnosis of hypertension. Patients with a blood pressure of 180/100 mmHg and above and no signs of end-organ damage were followed up. Forty patients were given sublingual captopril 25 mg, and the other 40 patients were given 40 mg of olmesartan, and they were allowed to swallow the drug with some water. Afterward, the patients were followed for 3 hours (with blood pressure and pulse measurements), and their blood pressure was measured and recorded at five-minute intervals. \u0000Results: The mean age of the patients receiving captopril was 60.70±11.43 years, and the mean age of the patients receiving olmesartan was 57.02±13.86 years. Of the patients receiving captopril, 19 (57.5%) were male, 21 (52.5%) were female, 17 (42.5%) of the patients receiving olmesartan were male and 23 (57.5%) were female. In this study, patients treated with captopril and olmesartan were monitored for 3 hours and the differences between them in pulse and blood pressure measurements were evaluated. When the systolic blood pressures were compared, the difference at the tenth minute was significant, but the difference between the other minutes was not significant. Differences in diastolic blood pressure and heart rate were not significant. \u0000Conclusion: Oral administration of olmesartan in emergency hypertensive patients may be an alternative to captopril due to its effectiveness in reducing mortality and morbidity.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126175739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Nergiz, S. Sezer, S. O. Altınkaya, M. Küçük, A. Ünsal, A. R. Odabaşı, H. Yüksel
TRAP sequence is a syndrome with poor prognosis seen in monochorionic twin pregnancies at the rate of 1/100. There is an acardiac “nonviable” fetus with multiple anomalies in the TRAP sequence and a pump fetus feeding this fetus through vascular anastomoses in the placenta. Mortality for acardiac twins is 100%. The mortality of the pump twin is around 50%, and death may be generally due to high flow rate heart failure and sometimes prematurity caused by polyhydramnios. Here, we presented an acardiac acephalous type TRAP case that applied to the Obstetrics and Gynecology Clinic of Amasya University Sabuncuoğlu Şerefeddin Training and Research Hospital. The case was 30 years old. The patient had the first pregnancy and reached this pregnancy with the IVF method. She did not have any disease. During the measurement of NT, the fetus of acardiac acephalous type was detected. Laser ablation was performed at the outer center at 18 weeks. All subsequent follow-ups were done by our center. While the patient had 39 weeks and 2 days of pregnancy, the pregnancy was terminated by performing cesarean due to primipara breech arrival.
{"title":"TRAP sequence; case report","authors":"S. Nergiz, S. Sezer, S. O. Altınkaya, M. Küçük, A. Ünsal, A. R. Odabaşı, H. Yüksel","doi":"10.51271/kmj-0027","DOIUrl":"https://doi.org/10.51271/kmj-0027","url":null,"abstract":"TRAP sequence is a syndrome with poor prognosis seen in monochorionic twin pregnancies at the rate of 1/100. There is an acardiac “nonviable” fetus with multiple anomalies in the TRAP sequence and a pump fetus feeding this fetus through vascular anastomoses in the placenta. Mortality for acardiac twins is 100%. The mortality of the pump twin is around 50%, and death may be generally due to high flow rate heart failure and sometimes prematurity caused by polyhydramnios. Here, we presented an acardiac acephalous type TRAP case that applied to the Obstetrics and Gynecology Clinic of Amasya University Sabuncuoğlu Şerefeddin Training and Research Hospital. The case was 30 years old. The patient had the first pregnancy and reached this pregnancy with the IVF method. She did not have any disease. During the measurement of NT, the fetus of acardiac acephalous type was detected. Laser ablation was performed at the outer center at 18 weeks. All subsequent follow-ups were done by our center. While the patient had 39 weeks and 2 days of pregnancy, the pregnancy was terminated by performing cesarean due to primipara breech arrival.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"219 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115976886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: The purpose of this study is to report the results of newborn hearing screening performed in 2017-2020 at the Kastamonu Education and Research Hospital, Turkey. Material and Method: Six thousand seven hundred and ninety newborns undergoing hearing screening between January 2017 and December 2019 at the Kastamonu Education and Research Hospital were included in this retrospective study. The screening ABR test was performed with all babies. Test findings retrieved from our hospital and the central database were subjected to analysis. Results: 4701 babies passed the 1st test, 1920 babies passed the 2nd test, 139 babies passed the 3rd test. Of the 30 babies who could not pass these 3 screening ABR tests and were referred to the reference center, 19 passed the test. Of the remaining 11 babies (0.162%), 7 (0.103%) had unilateral sensorineural hearing loss (SNHL) and 4 (0.058%) had bilateral SNHL. Conclusion: It is very important for hearing loss to be detected via screening tests in the first three months and for treatment and rehabilitation to be started within six months at the latest. These babies can thus acquire normal hearing and not lag behind their peers in terms of linguistic, social, and cognitive skill development.
{"title":"The newborn hearing screening results in Kastamonu Education and Research Hospital","authors":"","doi":"10.51271/kmj-0015","DOIUrl":"https://doi.org/10.51271/kmj-0015","url":null,"abstract":"Purpose: The purpose of this study is to report the results of newborn hearing screening performed in 2017-2020 at the Kastamonu Education and Research Hospital, Turkey. \u0000Material and Method: Six thousand seven hundred and ninety newborns undergoing hearing screening between January 2017 and December 2019 at the Kastamonu Education and Research Hospital were included in this retrospective study. The screening ABR test was performed with all babies. Test findings retrieved from our hospital and the central database were subjected to analysis.\u0000Results: 4701 babies passed the 1st test, 1920 babies passed the 2nd test, 139 babies passed the 3rd test. Of the 30 babies who could not pass these 3 screening ABR tests and were referred to the reference center, 19 passed the test. Of the remaining 11 babies (0.162%), 7 (0.103%) had unilateral sensorineural hearing loss (SNHL) and 4 (0.058%) had bilateral SNHL.\u0000Conclusion: It is very important for hearing loss to be detected via screening tests in the first three months and for treatment and rehabilitation to be started within six months at the latest. These babies can thus acquire normal hearing and not lag behind their peers in terms of linguistic, social, and cognitive skill development.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133305170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Cardiac depolarization occurs in patients experiencing pain from acute traumas, and changes in QT interval could indicate the state of ventricular depolarization. Thus, we aimed to determine the relationship between pain severity and QT interval in patients experiencing acute trauma. Material and Method: Seventy patients, who were conscutively- admitted to the Emergency Department due to moderate or severe trauma (study group), and sixty healthy individuals (control group) were included in this study. The QT interval was calculated for each group before and after analgesia and visual analog scale pain levels were recorded. Statistical analyses were performed using SPSS for Windows software (ver. 21.0; SPSS Inc., Chicago, IL, USA). Data are presented as medians±interquartile range (IQR). Statistical significance was determined using Mann-Whitney U, Wilcoxon, and chi-square tests, with a p-value <0.05 considered significant. Results: The mean age of patients with trauma and control patients was 31.50±25 years and 35.00±20 years, respectively. Among trauma patients, QT, RR and corrected QT (QTc) intervals were significantly different before and after analgesia (P<0.001). Similarly, the average pre-analgesia QT, RR and QTc values also differed between pre- and post-analgesia trauma patients (p=0.007, p<0.001, and p<0.001, respectively). However, no differences in QT values were observed before and after analgesia between patients experiencing moderate versus severe pain (p>0.05). Conclusion: In trauma patients, acute pain prolonged the QT interval, which reverted to normal following the administration of nonsteroidal anti-inflammatory drugs. However, additional comparative studies on this topic are required.
{"title":"The relationship between QT interval and pain severity in \u0000trauma patients in the emergency department","authors":"","doi":"10.51271/kmj-0018","DOIUrl":"https://doi.org/10.51271/kmj-0018","url":null,"abstract":"Aim: Cardiac depolarization occurs in patients experiencing pain from acute traumas, and changes in QT interval could indicate the state of ventricular depolarization. Thus, we aimed to determine the relationship between pain severity and QT interval in patients experiencing acute trauma.\u0000Material and Method: Seventy patients, who were conscutively- admitted to the Emergency Department due to moderate or severe trauma (study group), and sixty healthy individuals (control group) were included in this study. The QT interval was calculated for each group before and after analgesia and visual analog scale pain levels were recorded. Statistical analyses were performed using SPSS for Windows software (ver. 21.0; SPSS Inc., Chicago, IL, USA). Data are presented as medians±interquartile range (IQR). Statistical significance was determined using Mann-Whitney U, Wilcoxon, and chi-square tests, with a p-value <0.05 considered significant. \u0000Results: The mean age of patients with trauma and control patients was 31.50±25 years and 35.00±20 years, respectively. Among trauma patients, QT, RR and corrected QT (QTc) intervals were significantly different before and after analgesia (P<0.001). Similarly, the average pre-analgesia QT, RR and QTc values also differed between pre- and post-analgesia trauma patients (p=0.007, p<0.001, and p<0.001, respectively). However, no differences in QT values were observed before and after analgesia between patients experiencing moderate versus severe pain (p>0.05).\u0000Conclusion: In trauma patients, acute pain prolonged the QT interval, which reverted to normal following the administration of nonsteroidal anti-inflammatory drugs. However, additional comparative studies on this topic are required.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130873239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This report presents an unique lipoma arborescence case involving the knee joint in a 52-year-old male patient who is previously diagnosed with osteoarthritis, thereby undergoing symptomatical treatment for 3 years. In the course of symptomatic treatment, patients symptoms including pain, local tenderness, and pressure feeling were frequently exacerbated without improvement. Given the persistent symptoms; comparative assessment of knee radiographies and magnetic resonance imaging demonstrated gradual evolving changes over the years like increased joint effusion, pronounced semimembranosus-gastrocnemius bursitis along with villous synovial changes suggestive of lipoma arborescens. In this particular case report, we highlighted a peculiar case of lipoma arborescens extending into periarticular bursae over which developed in settings of degenerative knee joint.
{"title":"Secondary monoarticular lipoma arborescens extending to Baker cyst: case report","authors":"","doi":"10.51271/kmj-0013","DOIUrl":"https://doi.org/10.51271/kmj-0013","url":null,"abstract":"This report presents an unique lipoma arborescence case involving the knee joint in a 52-year-old male patient who is previously diagnosed with osteoarthritis, thereby undergoing symptomatical treatment for 3 years. In the course of symptomatic treatment, patients symptoms including pain, local tenderness, and pressure feeling were frequently exacerbated without improvement. Given the persistent symptoms; comparative assessment of knee radiographies and magnetic resonance imaging demonstrated gradual evolving changes over the years like increased joint effusion, pronounced semimembranosus-gastrocnemius bursitis along with villous synovial changes suggestive of lipoma arborescens. In this particular case report, we highlighted a peculiar case of lipoma arborescens extending into periarticular bursae over which developed in settings of degenerative knee joint.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122525044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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