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Assessing the power of AI: a comparative evaluation of large language models in generating patient education materials in dentistry. 评估人工智能的力量:在牙科患者教育材料生成中的大型语言模型的比较评估。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-18 DOI: 10.1038/s41405-025-00349-1
Gowri Sivaramakrishnan, Maryam Almuqahwi, Sufyan Ansari, Mohammed Lubbad, Emad Alagamawy, Kannan Sridharan

Background: This study evaluates the use of large language models (LLMs) in generating Patient Education Materials (PEMs) for dental scenarios, focusing on their reliability, readability, understandability, and actionability. The study aimed to assess the performance of four LLMs-ChatGPT-4.0, Claude 3.5 Sonnet, Gemini 1.5 Flash, and Llama 3.1-405b-in generating PEMs for four common dental scenarios.

Methods: A comparative analysis was conducted where five independent dental professionals assessed the materials using the Patient Education Materials Assessment Tool (PEMAT) to evaluate understandability and actionability. Readability was measured with Flesch Reading Ease and Level scores, and inter-rater reliability was assessed using Fleiss' Kappa.

Results: Llama 3.1-405b demonstrated the highest inter-rater reliability (Fleiss' Kappa: 0.78-0.89). ChatGPT-4.0 excelled in understandability, surpassing the PEMAT threshold of 70% in three of the four scenarios. Claude 3.5 Sonnet performed well in understandability for two scenarios but did not consistently meet the 70% threshold for actionability. ChatGPT-4.0 generated the longest responses, while Claude 3.5 Sonnet produced the shortest.

Conclusions: ChatGPT-4.0 demonstrated superior understandability, while Llama 3.1-405b achieved the highest inter-rater reliability. The findings indicate that further refinement and human intervention is necessary for LLM-generated content to meet the standards of effective patient education.

背景:本研究评估了大型语言模型(llm)在生成牙科情景患者教育材料(PEMs)中的使用,重点是它们的可靠性、可读性、可理解性和可操作性。该研究旨在评估四种llms (chatgpt -4.0, Claude 3.5 Sonnet, Gemini 1.5 Flash和Llama 3.1-405b)在为四种常见牙科场景生成PEMs方面的性能。方法:采用患者教育材料评估工具(Patient educational materials Assessment Tool, PEMAT)对5名独立的牙科专业人员进行材料评估,以评估材料的可理解性和可操作性。可读性采用Flesch Reading Ease和Level评分测量,信度采用Fleiss’Kappa评估。结果:羊驼3.1 ~ 405b具有最高的信度(Fleiss’Kappa: 0.78 ~ 0.89)。ChatGPT-4.0在可理解性方面表现出色,在四个场景中的三个场景中超过了70%的PEMAT阈值。克劳德3.5十四行诗在两种情景的可理解性方面表现良好,但在可操作性方面并未始终达到70%的门槛。ChatGPT-4.0产生了最长的回答,而Claude 3.5 Sonnet产生了最短的回答。结论:ChatGPT-4.0具有更好的可理解性,而Llama 3.1-405b具有最高的评分间可靠性。研究结果表明,法学硕士生成的内容需要进一步完善和人为干预,以满足有效患者教育的标准。
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引用次数: 0
Soft tissue attachment of human gingival fibroblasts to titanium dioxide nanotubes compared to commercially pure titanium and its alloys: a systematic review. 人牙龈成纤维细胞与二氧化钛纳米管的软组织附着:与商业纯钛及其合金的比较:系统综述。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-18 DOI: 10.1038/s41405-025-00293-0
Sara Baraka, Anu Sam, Marta Krysmann, Neil Cook, Waqar Ahmed, Fadi Barrak

Objective: This systematic review was conducted to evaluate the attachment of human gingival fibroblasts (HGFs) of the soft tissue, to titanium dioxide nanotubes (TNTs) compared to commercially pure titanium (cp-Ti) and its alloys, in in-vitro studies. It is postulated that the nanotopography of the TNTs provide cells with a biomimetic environment, allowing HGFs to form more focal adhesion (FA) attachment sites at the tubule edges.

Method: A comprehensive literature search was conducted on MEDLINE, DOSS, EMBASE and Google Scholar from January 2012 to January 2022. The identified studies were screened based on titles and abstracts for inclusion criteria. The relevant studies underwent data extraction. The risk of bias was assessed through the Office of Health Assessment and Translation (OHAT) tool.

Results: This systematic review included four studies evaluating cell proliferation, protein expression, gene expression and cell morphology of HGFs evocative of stronger and mature soft tissue attachment. A significant increase in the cell proliferation at TNTs compared to cp-Ti, at day 7 for three studies and at day 14, for one study was evident. In addition, a significant increase in the type 1 collagen protein expression at TNTs compared to cp-Ti, at day 6 for one study and day 7 for two studies. Enhanced cellular extensions from HGFs attached onto TNTs, compared to cp-Ti was observed in all four studies. All the primary effects evaluated suggest the formation of better interlaced fibers giving a stronger adhesion than the parallel ones which is the most relevant outcome of this research.

Conclusion: HGFs showed enhanced contact guidance onto TNTs but a true biological attachment was not confirmed. This review involved invitro studies which lack methodological rigor to compare among studies, lack information and have small sample sizes limiting effectiveness of parametric tests. The results may be unpredictable when translated to in-vivo studies mainly affected by confounding factors. Further research is needed to determine the precise mechanism of mechanical attachment between the soft tissue and the transmucosal surfaces.

目的:在体外研究中,比较纯钛(cp-Ti)及其合金与人牙龈成纤维细胞(HGFs)与二氧化钛纳米管(TNTs)的附着性。据推测,tnt的纳米形貌为细胞提供了一个仿生环境,允许hgf在小管边缘形成更多的焦点粘附(FA)附着位点。方法:于2012年1月~ 2022年1月在MEDLINE、DOSS、EMBASE、谷歌Scholar等数据库进行综合文献检索。根据标题和摘要筛选已确定的研究,以确定纳入标准。对相关研究进行数据提取。通过健康评估和翻译办公室(OHAT)工具评估偏倚风险。结果:本系统综述了四项研究,评估了HGFs的细胞增殖、蛋白表达、基因表达和细胞形态,唤起了更强和成熟的软组织附着。与cp-Ti相比,在三项研究中,在第7天,在第14天,在一项研究中,tnt的细胞增殖明显增加。此外,与cp-Ti相比,TNTs的1型胶原蛋白表达在第6天和第7天有显著增加。与cp-Ti相比,在所有四项研究中都观察到附着在tnt上的hgf增强了细胞延伸。所有的初步效果评估表明,形成更好的交错纤维,并提供更强的附着力比平行的纤维,这是本研究最相关的结果。结论:HGFs显示了与tnt的增强接触引导,但尚未证实其真正的生物附着。本综述涉及的体外研究缺乏方法上的严谨性,无法在研究之间进行比较,缺乏信息,样本量小,限制了参数检验的有效性。当转化为主要受混杂因素影响的体内研究时,结果可能不可预测。软组织与粘膜表面机械附着的确切机制有待进一步研究。
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引用次数: 0
Predictors of mothers' preventive behaviors for children's dental trauma: a cross-sectional study using the health belief model. 母亲预防儿童牙外伤行为的预测因素:基于健康信念模型的横断面研究
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-12 DOI: 10.1038/s41405-025-00346-4
Esmaeil Fakharian, Mojtaba Sehat, Azam Jahangirimehr, Hossein Akbari, KHadijeh Kalanfarmanfarma, Soudabeh Yarmohammadi

Objective: Dental traumas are one of the most common reasons for children to visit the dentist. This study aimed to investigate the predictors of mothers' behavior based on the health belief model (HBM) for the prevention of dental trauma in 7-12-year-old children.

Methods: The current cross-sectional study was conducted on 700 mothers in Kashan city in 19 September 2023 to 2 March 2024 included in the study by multi-stage random cluster sampling method. The data collection tool was a valid and reliable researcher-made questionnaire consisting of demographic information, Knowledge, constructs of HBM, and preventive behavior for dental trauma. Data were analyzed using SPSS 21 and descriptive statistics (standard deviation, mean, median and range), inferential tests (Pearson correlation coefficient, regression) and path analysis to test the direct and indirect effect of model constructs on the dependent variable by AMOS software.

Results: Knowledge (r = 0.365, P < 0.001), perceived benefits (r = 0.166, P < 0.001), and self-efficacy (r = 0.425, P < 0.001) had a positive correlation and perceived barriers (r = -0.313, P < 0.001) had a negative correlation and a significant relationship with mothers' preventive behaviors. Knowledge, perceived barriers and self-efficacy explained and predicted a total of 33% of preventive behavior changes (R-Square=0.329). In the path analysis, self-efficacy (β = 0.327, P < 0.001), knowledge (β = 0.251, P < 0.001) and perceived barriers (β = -0.242, P < 0.001) had the most direct effect, and perceived severity (β = -0.017), perceived susceptibility (β = -0.004), and perceived benefits (β = 0.092) had an indirect effect on mothers' preventive behaviors (P < 0.05).

Conclusion: Knowledge, self-efficacy, and perceived barriers were key predictors of mothers' preventive behaviors. Interventions should target these factors to improve dental trauma prevention in children. The HBM effectively identified these predictors.

目的:牙外伤是儿童去看牙医最常见的原因之一。本研究旨在探讨基于健康信念模型(HBM)的母亲行为对7-12岁儿童牙外伤预防的影响因素。方法:采用多阶段随机整群抽样方法,对2023年9月19日至2024年3月2日纳入研究的喀山市700名母亲进行横断面研究。数据收集工具是一份有效可靠的调查问卷,包括人口统计信息、知识、HBM结构和牙外伤预防行为。数据分析采用SPSS 21,描述性统计(标准差、均值、中位数、极差)、推理检验(Pearson相关系数、回归)和通径分析,采用AMOS软件检验模型构建对因变量的直接和间接影响。结果:知识(r = 0.365, P)。结论:知识、自我效能感和感知障碍是母亲预防行为的关键预测因素。干预措施应针对这些因素,以改善儿童牙外伤的预防。HBM有效地识别了这些预测因子。
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引用次数: 0
Occlusal splint effects on visual capacities in patients with temporomandibular disorders (TMD): a prospective interventional cohort study. 咬合夹板对颞下颌疾病(TMD)患者视力的影响:一项前瞻性介入队列研究。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-09 DOI: 10.1038/s41405-025-00337-5
Shahnawaz Khijmatgar, Gianluca Martino Tartaglia, Andrea Sardella, Alessandro Marchesi, Roberto Marchesi, Clarita Pellegrini

Objectives: The temporomandibular joint system and visual apparatus seem to be correlated. Our study aimed to examine the potential effects of occlusal splints on visual capacities (accommodation and ocular convergence) in individuals with temporomandibular disorders, followed for a period of 6 months and 1 year, assessing changes over this timeframe.

Materials and methods: Forty-two subjects were enrolled in a year-long study conducted at the Operative Unit of Odontostomatology of ASST Santi Paolo e Carlo, in collaboration with the University of Milan, Italy. A gnathological examination was followed by an orthoptic assessment using the stick of Duane and measuring convergence and accommodation at three jaw positions at different time points (T0, T1, T2, T3).

Results: After 6 months of occlusal splint therapy, an improvement in visual abilities at maximum intercuspation and resting positions was observed. In contrast, the open-mouth position did not yield statistically significant results. Further assessments at 1 year did not show significant changes. Occlusal splint therapy appears to positively influence visual capacities (in maximum intercuspation and resting positions). While the open-mouth position did not exhibit significant improvements.

Conclusion: Our study results highlight the importance of considering jaw positions in evaluating visual function, suggesting the possible integration of occlusal splints with an orthoptic assessment in comprehensive TMD management.

目的:颞下颌关节系统与视觉器官似乎是相关的。我们的研究旨在检查咬合夹板对颞下颌疾病患者视觉能力(调节和眼会聚)的潜在影响,随访6个月和1年,评估这段时间内的变化。材料和方法:42名受试者参加了一项为期一年的研究,该研究由圣保罗市口腔外科医生与意大利米兰大学合作进行。随后进行口腔病理学检查,使用Duane棒进行正视评估,并在不同时间点(T0, T1, T2, T3)测量三个颌骨位置的收敛和调节。结果:经过6个月的咬合夹板治疗,观察到最大间歇位和休息位的视力改善。相比之下,张口姿势没有产生统计学上显著的结果。1年后的进一步评估没有显示出明显的变化。咬合夹板治疗似乎对视力有积极的影响(在最大间歇和休息位置)。而张开嘴的姿势没有明显的改善。结论:我们的研究结果强调了在评估视觉功能时考虑颌骨位置的重要性,提示在全面的TMD治疗中,可能将咬合夹板与正视评估结合起来。
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引用次数: 0
Effectiveness of a digital educational system on the learners' performance in preclinical fixed prosthodontic training. 数字教育系统对学习者临床前固定义齿训练表现的影响。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-27 DOI: 10.1038/s41405-025-00344-6
Lan-Anh Thi Pham, Tri Minh Doan, Thien-Thuy-Truc Tran, Van-Khoa Pham

Objectives: The purpose of this study was to evaluate the effectiveness of the digital education system on the crown preparation performance of dental students in repetitive preclinical training sessions, and students' perceptions of the digital software in fixed prosthodontic practice.

Material and methods: Forty dental students in the third year were recruited for the preclinical training of all-ceramic crown preparation on the lower right first molar in seven sessions. The first session (S1) included the initial didactic course and the first crown preparation practice with the instructor's guidance. The second session (S2) comprised training in using the pedagogical Dental Teacher system. Students participated in five consecutive practice sessions (S2-S6), receiving only digital feedback. The seventh session (S7) was conducted with no digital or instructor support for all students. The abutment teeth were compared to the original tooth and measured via Exocad software. Each preparation received ten component scores corresponding to ten specific areas of the tooth and an overall score (out of 10) based on how well it matched the criteria. Participants were asked to complete a questionnaire survey to investigate their perception of the digital education software.

Results: In the occlusal surface, the scores significantly differed in the third/fourth session compared to the first session (p = 0.037), and this difference remained throughout the study (p = 0.002 for the fourth session and p < 0.001 for the fifth, sixth, and seventh sessions). No significant difference was found for the buccal and lingual surfaces. In the proximal surfaces, the reduction scores of the occlusal second differed significantly between sessions 1 and 5 and between session 1 and session 6. However, no difference in scores from the last and first sessions was found. In the cervical second, no score difference was observed during the study. The overall scores of tooth removal rose from a baseline of 6.52 ± 0.79 to 7.14 ± 0.67 in session 5 (p = 0.033) and 7.35 ± 0.75 in session 6 (p < 0.001), before falling to 7.05 ± 0.74 in the last session (p = 0.203). Participants using digital software reported high satisfaction (92.5-95.0%) and expressed interest in future use for prosthodontic training (100%). However, over 50% of students assumed that digital software was incapable of substituting for teachers for guidance or assessment of crown preparation.

Conclusion: The findings showed that the digital software improved students' overall performance in preclinical prosthodontics and facilitated precision in some specific areas of tooth preparation. Preclinical crown preparation training benefits from the utilization of digital evaluation software; however, this digital pedagogic system cannot entirely replace the teachers' roles.

目的:本研究的目的是评估数字教育系统对牙科学生在重复性临床前培训课程中冠准备表现的有效性,以及学生在固定修复实践中对数字软件的认知。材料与方法:招募40名大三学生,分7期进行右下第一磨牙全瓷冠预备的临床前训练。第一阶段(S1)包括最初的教学课程和在指导员指导下的第一次冠预备练习。第二部分(S2)包括使用教学牙科教师系统的培训。学生们连续参加了五次练习(S2-S6),只收到数字反馈。第七期(S7)是在没有数字或教师支持的情况下进行的。将基牙与原牙进行比较,并通过Exocad软件进行测量。每个准备得到十个组成部分的分数,对应于牙齿的十个特定区域,并根据它与标准的匹配程度获得总分(满分10分)。参与者被要求完成一份问卷调查,以调查他们对数字教育软件的看法。结果:在咬合面方面,第三/第四阶段的得分与第一阶段相比有显著差异(p = 0.037),并且这种差异在整个研究过程中一直存在(p = 0.002)。结论:研究结果表明,数字软件提高了学生在临床前修复的整体表现,并提高了牙齿准备的某些特定区域的准确性。临床前冠预备培训受益于数字化评估软件的应用;然而,这种数字化教学系统并不能完全取代教师的角色。
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引用次数: 0
Key determinants of health and wellbeing of dental nurses: a rapid review of over two decades of research. 牙科护士健康和福祉的关键决定因素:二十多年研究的快速回顾。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-27 DOI: 10.1038/s41405-025-00314-y
Nana Adwoa Opoku-Ansah, Jennifer E Gallagher, Victoria Niven

Aim: To review the literature on the key determinants of health and well-being amongst dental nurses.

Method: A rapid review of the literature using Khangura's approach across seven health and social science databases was conducted (2002 to 2023), through OVID and the Cochrane Library, professional and health system databases-informed by past research exploring the health and well-being of dental professionals. A two-stage review process was implemented where records were screened by the primary researcher, with a second researcher independently reviewing 10% of the papers according to agreed inclusion and exclusion criteria. Data extraction and qualitative synthesis of the included studies were conducted, and quality was assessed using a Mixed Methods Appraisal Tool.

Results: Out of 4,450 identified papers, 44 underwent full-text screening and 37 studies were included for analysis. Four studies were of high quality, 13 moderate-high, 14 moderate-low and six low-quality. The overall health and well-being of dental nurses was variable and the determinants influencing well-being were grouped into micro-, meso- and macro-level factors with evidence across the three domains with the most frequently identified determinant being workplace characteristics. Dental nurses with extended duties had higher job satisfaction. There was evidence that during the COVID-19 pandemic, there were increased levels of anxiety, stress, burnout and isolation among dental nurses.

Conclusion: The body of research suggests that dental nurses' health and well-being determinants are comparable to those of other dental professionals. Dental nurses in different countries had similar determinants. It is important to recognise and improve the determinants of dental nurses' health and well-being to support retention within the profession. Organisational and policy changes may help improve the well-being of dental nurses. Further investigation into dental nurses' health and well-being over time is needed.

目的:回顾关于牙科护士健康和幸福的关键决定因素的文献。方法:通过OVID和Cochrane图书馆、专业和卫生系统数据库,利用Khangura的方法对七个健康和社会科学数据库(2002年至2023年)的文献进行了快速回顾,并参考了过去探索牙科专业人员健康和福祉的研究。实施了两阶段的审查过程,其中记录由主要研究人员筛选,第二研究人员根据商定的纳入和排除标准独立审查10%的论文。对纳入的研究进行数据提取和定性综合,并使用混合方法评估工具对质量进行评估。结果:在4450篇确定的论文中,44篇进行了全文筛选,37篇研究被纳入分析。4项研究为高质量研究,13项为中高质量研究,14项为中低质量研究,6项为低质量研究。牙科护士的整体健康和福祉是可变的,影响福祉的决定因素分为微观、中观和宏观层面的因素,证据跨越三个领域,最常确定的决定因素是工作场所特征。延长工作时间的牙科护士工作满意度较高。有证据表明,在2019冠状病毒病大流行期间,牙科护士的焦虑、压力、倦怠和孤立程度有所增加。结论:研究表明,牙科护士的健康和幸福的决定因素是相当的其他牙科专业人员。不同国家的牙科护士有相似的决定因素。重要的是要认识和改善牙科护士的健康和福祉的决定因素,以支持保留在专业范围内。组织和政策的变化可能有助于提高牙科护士的福利。需要对牙科护士的健康和福祉进行进一步的调查。
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引用次数: 0
Knowledge, attitudes, and practices among Syrian dentists towards minimal invasive dentistry and chemomechanical caries removal: a cross-sectional study. 叙利亚牙医对微创牙科和化学机械除龋的知识、态度和实践:一项横断面研究。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-27 DOI: 10.1038/s41405-025-00343-7
Dana Alakkad, Mohammed N Al-Shiekh, Mawia Karkoutly, Mohannad Laflouf

Objectives: This study aimed to evaluate and compare the knowledge, perceptions, attitudes, and clinical experiences of general dental practitioners (GPDs), pediatric dentists (PDs), and other dental specialists (ODSs) regarding minimal invasive dentistry (MID) in Damascus, Syria.

Materials and methods: It was an observational, quantitative study utilizing a questionnaire-based online survey. Demographic information data collected included gender, age, specialty, years of practice, number of patients treated per day, and daily working hours. The knowledge assessment evaluated participants' understanding of MID, their awareness of preventive treatment procedures, previous training, and sources of knowledge. Subsequently, attitude toward MID and chemomechanical caries removal (CMCR) questions assessed participants' perspectives on MID principles and their stance on CMCR. In addition, clinical practices explored the participants' application of CMCR in their daily practice. Descriptive statistics were utilized to illustrate the frequency and percentage of categorical variables. A chi-square test was performed to investigate the relationship between specialization, years of experience, and knowledge of the MID and CMCR. p-value below 0.05 was deemed statistically significant.

Results: A total of 252 participants were included in the study. According to MID's knowledge level, most respondents agreed on the importance of fluoride for remineralization (90.1%) and using sealants for high caries-risk children (64.7%). Caries risk assessments (CRA) are strongly agreed (90%). A small percentage of dentists reported rarely using the CRA technique. However, approximately one-third of them consistently evaluated patients' dietary habits. Additionally, 30.2% frequently assessed the patient's current fluoride exposure. 67.5% were familiar with the CMCR technique. The chi-square test revealed a significant relationship between knowledge and years of experience, particularly for those with 0-2 years of experience (p = 0.006). However, specialization did not impact knowledge, as indicated by the p = 0.076. Furthermore, the chi-square test showed that years of experience did not significantly affect knowledge of the technique.

Conclusions: This research provides important perspectives on how dental professionals are adopting MID and CMCR. Although practitioners received MID training during their university studies, only a small percentage expressed complete confidence in their abilities, indicating that dental training programs could be enhanced. It was also identified a strong consensus regarding the advantages of fluoride and preventive measures. However, views varied concerning specific diagnostic and treatment techniques, particularly ART and pit and fissure sealants in permanent teeth.

目的:本研究旨在评估和比较叙利亚大马士革普通牙科医生(gpd)、儿科牙医(pd)和其他牙科专家(ODSs)关于微创牙科(MID)的知识、观念、态度和临床经验。材料和方法:这是一项观察性的定量研究,采用基于问卷的在线调查。收集的人口统计信息数据包括性别、年龄、专业、从业年限、每天治疗的患者数量和每日工作时间。知识评估评估了参与者对MID的理解,他们对预防治疗程序的认识,以前的培训和知识来源。随后,对MID和化学机械除龋(CMCR)的态度问题评估了参与者对MID原则的看法和他们对CMCR的立场。此外,临床实践还探讨了参与者在日常实践中对CMCR的应用。使用描述性统计来说明分类变量的频率和百分比。采用卡方检验来调查专业化、经验年数和MID和CMCR知识之间的关系。p值小于0.05认为有统计学意义。结果:本研究共纳入252名受试者。根据MID的知识水平,大多数受访者同意氟化物对再矿化的重要性(90.1%)和对高龋风险儿童使用密封剂(64.7%)。龋齿风险评估(CRA)得到强烈认同(90%)。一小部分牙医报告很少使用CRA技术。然而,其中大约三分之一的人始终如一地评估患者的饮食习惯。此外,30.2%的人经常评估患者目前的氟化物暴露情况。67.5%的人熟悉CMCR技术。卡方检验显示知识与经验年数之间存在显著关系,特别是对于0-2年经验的人(p = 0.006)。然而,专业化并不影响知识,p = 0.076表明。此外,卡方检验表明,多年的经验并没有显著影响技术的知识。结论:本研究为牙科专业人员如何采用MID和CMCR提供了重要的视角。尽管从业者在大学期间接受过MID培训,但只有一小部分人对自己的能力表示完全自信,这表明牙科培训计划可以得到加强。会议还确定了关于氟化物的优点和预防措施的强烈共识。然而,关于具体的诊断和治疗技术,特别是抗逆转录病毒治疗和恒牙窝和裂隙密封,意见不一。
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引用次数: 0
Polymer waste and pollution in oral healthcare clinics: a systematic review. 口腔保健诊所的聚合物废物和污染:系统综述。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-25 DOI: 10.1038/s41405-025-00342-8
Anne Margrete Gussgard, Asbjørn Jokstad

Background: Modern oral healthcare extensively uses polymer items and devices derived from various monomeric compounds. These materials are essential for personal protective equipment, infection barriers, packaging, and intraoral devices. The COVID-19 pandemic has led to an increased reliance on single-use polymer items, causing supply chain disruptions and higher costs. This systematic review explores the extent of polymer waste and pollution generated in oral healthcare clinics.

Materials and methods: A systematic review protocol was registered with PROSPERO and was formatted according to PRISMA guidelines and SWiM recommendations. Eligibility criteria included studies that provided quantified estimates of polymer waste or pollution in air or wastewater from oral healthcare clinics. Comprehensive electronic searches were conducted across several bibliometric databases, followed by data extraction and risk of bias assessments performed by two independent reviewers.

Results: A total of thirty studies were included in the review. Sixteen papers reported on waste audits that detailed polymer waste data, while eight studies focused on pollution caused by polymer nano- and microparticles in clinical settings. Additionally, six experimental studies investigated potential leakage of monomeric eluates or polymer particles from landfill waste. There was significant variation in the amount of polymer waste generated per patient, ranging from 81 to 384 g per operatory room per day. On-site sampling revealed the presence of polymer nano- and microparticles in the clinic air, which was influenced by dental procedures and the equipment used.

Conclusions: This review highlights critical knowledge gaps about polymer waste and pollution in oral healthcare clinics. The variability of study designs limited the feasibility of meta-analysis. Current evidence indicates substantial polymer waste generation, particularly from single-use items, as well as potential environmental impacts from monomeric eluates and polymer microparticles. Future research should focus on sustainable polymer waste management solutions to reduce environmental pollution in oral healthcare settings.

背景:现代口腔保健广泛使用各种单体化合物衍生的聚合物项目和设备。这些材料对于个人防护装备、感染屏障、包装和口腔内装置是必不可少的。COVID-19大流行导致对一次性聚合物物品的依赖增加,导致供应链中断和成本上升。本系统综述探讨了口腔保健诊所产生的聚合物废物和污染的程度。材料和方法:系统评价方案在PROSPERO注册,并根据PRISMA指南和SWiM建议格式化。资格标准包括提供定量估计的聚合物废物或口腔保健诊所空气或废水污染的研究。在几个文献计量数据库中进行了全面的电子检索,随后由两名独立审稿人进行了数据提取和偏倚风险评估。结果:本综述共纳入30项研究。16篇论文报告了详细介绍聚合物废物数据的废物审计,而8项研究侧重于临床环境中聚合物纳米和微粒造成的污染。此外,六项实验研究调查了填埋场垃圾中单体洗脱物或聚合物颗粒的潜在泄漏。每位患者产生的聚合物废物量差异很大,每个手术室每天产生81至384克不等。现场取样显示,诊所空气中存在聚合物纳米和微粒,这受到牙科手术和所用设备的影响。结论:这篇综述强调了口腔保健诊所关于聚合物废物和污染的关键知识差距。研究设计的可变性限制了meta分析的可行性。目前的证据表明,产生大量聚合物废物,特别是来自一次性物品,以及单体洗脱物和聚合物微粒的潜在环境影响。未来的研究应侧重于可持续的聚合物废物管理解决方案,以减少口腔保健机构的环境污染。
{"title":"Polymer waste and pollution in oral healthcare clinics: a systematic review.","authors":"Anne Margrete Gussgard, Asbjørn Jokstad","doi":"10.1038/s41405-025-00342-8","DOIUrl":"10.1038/s41405-025-00342-8","url":null,"abstract":"<p><strong>Background: </strong>Modern oral healthcare extensively uses polymer items and devices derived from various monomeric compounds. These materials are essential for personal protective equipment, infection barriers, packaging, and intraoral devices. The COVID-19 pandemic has led to an increased reliance on single-use polymer items, causing supply chain disruptions and higher costs. This systematic review explores the extent of polymer waste and pollution generated in oral healthcare clinics.</p><p><strong>Materials and methods: </strong>A systematic review protocol was registered with PROSPERO and was formatted according to PRISMA guidelines and SWiM recommendations. Eligibility criteria included studies that provided quantified estimates of polymer waste or pollution in air or wastewater from oral healthcare clinics. Comprehensive electronic searches were conducted across several bibliometric databases, followed by data extraction and risk of bias assessments performed by two independent reviewers.</p><p><strong>Results: </strong>A total of thirty studies were included in the review. Sixteen papers reported on waste audits that detailed polymer waste data, while eight studies focused on pollution caused by polymer nano- and microparticles in clinical settings. Additionally, six experimental studies investigated potential leakage of monomeric eluates or polymer particles from landfill waste. There was significant variation in the amount of polymer waste generated per patient, ranging from 81 to 384 g per operatory room per day. On-site sampling revealed the presence of polymer nano- and microparticles in the clinic air, which was influenced by dental procedures and the equipment used.</p><p><strong>Conclusions: </strong>This review highlights critical knowledge gaps about polymer waste and pollution in oral healthcare clinics. The variability of study designs limited the feasibility of meta-analysis. Current evidence indicates substantial polymer waste generation, particularly from single-use items, as well as potential environmental impacts from monomeric eluates and polymer microparticles. Future research should focus on sustainable polymer waste management solutions to reduce environmental pollution in oral healthcare settings.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"11 1","pages":"52"},"PeriodicalIF":2.5,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility of a rapid C-reactive protein chairside point-of-care test for detecting inflammation in exposed dental pulp: a pilot exploratory study. 一种快速的c反应蛋白椅子旁的护理点测试的可行性,用于检测暴露牙髓的炎症:一项试点探索性研究。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-23 DOI: 10.1038/s41405-025-00340-w
Mohamed Taha Elfezary, Ahmed Safaa Waly, Eman Hamdy Mohamed

Objective/aim: Dental pulp inflammation is a critical condition in endodontics. Traditional diagnostic methods, such as patient pain history and percussion tests, often lack accuracy in reflecting the true status of pulp inflammation. This study explores the feasibility of using a rapid C-reactive protein (CRP) chairside point-of-care (POC) test as a potential adjunctive tool for detecting dental pulp inflammation. The findings provide preliminary insights to inform future larger-scale validation studies.

Materials and methods: This pilot cross-sectional observational study included 20 patients with deep carious lesions. Blood samples were collected from exposed pulp tissue under sterile conditions and analyzed using the CRP rapid POC test (index test). Patient pain history (clinical reference test) and percussion test outcomes were documented. The study assessed feasibility and preliminary diagnostic trends based on test performance and associations with clinical indicators.

Results: The CRP rapid POC test yielded positive results in 55% of cases. Preliminary findings suggest a potential association between CRP levels and percussion test results (p < 0.001), while no significant correlation was observed between CRP levels and patient pain history. The test demonstrated an observed sensitivity of 94.3%, specificity of 87.1%, positive predictive value (PPV) of 90.7%, and negative predictive value (NPV) of 91.9%. However, given the small sample size, these estimates should be interpreted with caution, and further research with larger cohorts is necessary for validation.

Conclusion: This pilot study suggests that the CRP rapid POC test may have potential as a diagnostic aid for detecting dental pulp inflammation. However, these findings are preliminary, and further validation through larger studies and gold-standard comparisons is necessary before clinical implementation can be considered.

目的:牙髓炎症是牙髓学的重要疾病。传统的诊断方法,如患者疼痛史和叩诊试验,往往缺乏反映牙髓炎症真实状态的准确性。本研究探讨了使用快速c反应蛋白(CRP)椅边护理点(POC)测试作为检测牙髓炎症的潜在辅助工具的可行性。这些发现为未来更大规模的验证研究提供了初步的见解。材料和方法:本前瞻性横断面观察研究纳入20例深部龋齿病变患者。在无菌条件下从暴露的牙髓组织中采集血样,采用CRP快速POC试验(指数试验)进行分析。记录患者疼痛史(临床参考试验)和叩击试验结果。该研究评估了可行性和初步诊断趋势,基于测试性能和与临床指标的关联。结果:CRP快速POC试验在55%的病例中呈阳性。初步结果提示CRP水平与叩击试验结果之间可能存在关联(p结论:本初步研究提示CRP快速POC试验可能有潜力作为检测牙髓炎症的诊断辅助手段。然而,这些发现是初步的,在考虑临床实施之前,需要通过更大规模的研究和金标准比较进一步验证。
{"title":"Feasibility of a rapid C-reactive protein chairside point-of-care test for detecting inflammation in exposed dental pulp: a pilot exploratory study.","authors":"Mohamed Taha Elfezary, Ahmed Safaa Waly, Eman Hamdy Mohamed","doi":"10.1038/s41405-025-00340-w","DOIUrl":"10.1038/s41405-025-00340-w","url":null,"abstract":"<p><strong>Objective/aim: </strong>Dental pulp inflammation is a critical condition in endodontics. Traditional diagnostic methods, such as patient pain history and percussion tests, often lack accuracy in reflecting the true status of pulp inflammation. This study explores the feasibility of using a rapid C-reactive protein (CRP) chairside point-of-care (POC) test as a potential adjunctive tool for detecting dental pulp inflammation. The findings provide preliminary insights to inform future larger-scale validation studies.</p><p><strong>Materials and methods: </strong>This pilot cross-sectional observational study included 20 patients with deep carious lesions. Blood samples were collected from exposed pulp tissue under sterile conditions and analyzed using the CRP rapid POC test (index test). Patient pain history (clinical reference test) and percussion test outcomes were documented. The study assessed feasibility and preliminary diagnostic trends based on test performance and associations with clinical indicators.</p><p><strong>Results: </strong>The CRP rapid POC test yielded positive results in 55% of cases. Preliminary findings suggest a potential association between CRP levels and percussion test results (p < 0.001), while no significant correlation was observed between CRP levels and patient pain history. The test demonstrated an observed sensitivity of 94.3%, specificity of 87.1%, positive predictive value (PPV) of 90.7%, and negative predictive value (NPV) of 91.9%. However, given the small sample size, these estimates should be interpreted with caution, and further research with larger cohorts is necessary for validation.</p><p><strong>Conclusion: </strong>This pilot study suggests that the CRP rapid POC test may have potential as a diagnostic aid for detecting dental pulp inflammation. However, these findings are preliminary, and further validation through larger studies and gold-standard comparisons is necessary before clinical implementation can be considered.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"11 1","pages":"51"},"PeriodicalIF":2.5,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144133182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The cross-cultural adaptation and psychometric evaluation of a Chinese version of the postoperative symptom severity (PoSSe) scale. 中文版术后症状严重程度(PoSSe)量表的跨文化适应与心理测量评估。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-22 DOI: 10.1038/s41405-025-00333-9
Xiang Li, Zefan Niu, Chen Gao, Annika Kroeger, Georgios Tsakos, Bolong Li, Jiaqi Zhu, Gang Chen, Thomas Dietrich

Background: The postoperative symptom severity (PoSSe) scale, which was developed in the UK, measures the impact of postoperative morbidity on patients' quality of life after lower third molar surgery. It has recently been used in Chinese populations but without having been adapted and validated for these populations. The aim of this study was to cross-culturally adapt and psychometrically evaluate a Chinese version (Simplified Chinese) of the PoSSe scale for applications in third molar surgery in Chinese patient populations.

Methods: We employed a rigorous multi-step cross-cultural adaptation process, including forward and backward translation followed by pilot testing, where participants documented the relevance and ease of understanding of the PoSSe items. The psychometric evaluation of the final Chinese version took place in a sample of 101 patients undergoing lower third molar surgery in Tianjin, China. Cronbach's Alpha (α) coefficient was calculated for the reliability evaluation, while the Spearman correlation coefficient (rs) and Pearson's correlation coefficient (r) were used for validity assessment.

Results: The PoSSe scale demonstrated excellent internal consistency (Cronbach's α = 0.80 for the whole sample; α = 0.80 among patients with bone removal during surgery; α = 0.81 among patients without bone removal during surgery). For validity assessment, PoSSe scores had statistically significant associations with the extent of surgical trauma (osteotomy and duration of surgery), self-reported pain and clinically assessed trismus. The strength of these associations varied between the two groups (with and without bone removal during surgery) in the expected direction. The results suggest that the Chinese version of the PoSSe scale has acceptable linguistic clarity, cultural relevance, and context appropriateness, showing excellent internal consistency and validity and can be confidently used for clinical and research applications in Chinese patient populations.

Conclusions: The PoSSe scale has been successfully cross-culturally adapted for postoperative use among Chinese patients undergoing third molar surgery and demonstrated successful psychometric assessment for its reliability and validity, which allows future informative studies in China, also in terms of comparison across countries involving China that could assess the cultural equivalence of the measure.

背景:英国开发的术后症状严重程度(PoSSe)量表衡量下第三磨牙手术后术后发病率对患者生活质量的影响。它最近在中国人群中使用,但没有针对这些人群进行调整和验证。本研究的目的是跨文化适应和心理测量学评估中文版本的PoSSe量表(简体中文)在中国第三磨牙手术患者群体中的应用。方法:我们采用了严格的多步骤跨文化适应过程,包括向前和向后翻译,然后是试点测试,参与者记录了PoSSe项目的相关性和易于理解性。最终中文版的心理测量评估是在中国天津接受下第三磨牙手术的101例患者样本中进行的。信度评价采用Cronbach’s Alpha (α)系数,效度评价采用Spearman相关系数(rs)和Pearson相关系数(r)。结果:PoSSe量表具有良好的内部一致性(整个样本的Cronbach's α = 0.80;术中剔骨患者的α = 0.80;手术中未取骨的患者α = 0.81)。对于效度评估,PoSSe评分与手术创伤程度(截骨和手术持续时间)、自我报告的疼痛和临床评估的牙关有统计学显著相关。在两组之间,这些关联的强度在预期的方向上有所不同(手术中有和没有去骨)。结果表明,中文版的PoSSe量表具有可接受的语言清晰度、文化相关性和上下文适当性,具有良好的内部一致性和有效性,可以自信地用于中国患者群体的临床和研究应用。结论:PoSSe量表已经成功地跨文化适应于中国第三磨牙手术患者的术后使用,并成功地对其进行了信度和效度的心理测量评估,这使得未来在中国的信息性研究成为可能,也可以在涉及中国的国家之间进行比较,以评估该量表的文化等效性。
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引用次数: 0
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