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Factors involved in the remission of oral lichen planus treated with topical corticosteroids. 使用局部皮质类固醇治疗口腔扁平苔藓的缓解因素。
IF 3 Q2 Dentistry Pub Date : 2024-05-08 DOI: 10.1038/s41405-024-00217-4
Poosit Wongpakorn, Soranun Chantarangsu, Chanwit Prapinjumrune

Aim: To determine the factors that affected the complete clinical remission of oral lichen planus (OLP) treated with topical corticosteroids.

Material and methods: We retrospectively evaluated the charts of patients diagnosed as OLP. Age, sex, current medical conditions, medications, type of OLP, Thongprasom score, pain level assessed by a numeric rating scale (NRS), Candida infection, topical steroid treatment preparation, duration of treatment until the first complete clinical remission, and follow-up duration were assessed as variables.

Results: In total 100 patients, after complete remission, 22 patients reported a relapse within 1.5-45 months, with a mean of 15.6 ± 13.2 months. Age, duration, gingiva and vestibule area, hypertension, dyslipidemia, Thongprasom score, preparation and topical corticosteroid potency were factors affecting the remission. Multivariate logistic regression analysis revealed that the patients' age and duration of treatment were significant factors after adjusted for age, sex, and independent factors with a P-value < 0.1 in the univariate analysis. The likelihood of having incomplete remission of the OLP lesion increased by 7.9% for every year increase in age and increased by 2.3% for every month of treatment.

Conclusions: There are many different factors between the complete remission and incomplete remission groups. However, age and duration of treatment were significant factors affecting the remission of OLP.

目的:确定影响使用局部皮质类固醇激素治疗的口腔扁平苔藓(OLP)临床完全缓解的因素:我们对确诊为 OLP 的患者病历进行了回顾性评估。年龄、性别、目前的医疗状况、药物、OLP类型、Thongprasom评分、用数字评分量表(NRS)评估的疼痛程度、念珠菌感染、外用类固醇治疗制剂、首次临床完全缓解前的治疗持续时间以及随访持续时间均作为变量进行评估:在总共 100 名患者中,有 22 名患者在完全缓解后的 1.5-45 个月内复发,平均复发时间为(15.6 ± 13.2)个月。年龄、病程、牙龈和前庭面积、高血压、血脂异常、Thongprasom评分、制剂和外用皮质类固醇药效是影响缓解的因素。多变量逻辑回归分析显示,在对年龄、性别和独立因素进行调整后,患者的年龄和治疗时间是显著因素,P 值为 结论:完全缓解组和不完全缓解组之间存在许多不同的因素。然而,年龄和治疗时间是影响 OLP 缓解的重要因素。
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引用次数: 0
Adult attitudes to sustainable dentistry in Trinidad and Tobago and their willingness to accept alternatives 特立尼达和多巴哥成年人对可持续牙科治疗的态度及其接受替代方案的意愿
IF 3 Q2 Dentistry Pub Date : 2024-05-01 DOI: 10.1038/s41405-024-00216-5
Trudee Hoyte, Akini James, Deysha Carr, Abbinah Donatien Andrew Teelucksingh, Peter Mossey

Introduction

Attitudes towards and willingness to accept alternatives for sustainable dentistry in Trinidad and Tobago have never been assessed. Market research aids in the understanding of the behaviours of people. Since change can be enacted by public pressure, it is worth engaging the public through research to understand their attitudes and which changes they are willing to accept.

Method

A self-administered questionnaire was distributed to private and public dental clinics. The questionnaire assessed attitude towards and willingness to accept alternatives which decrease the effect of dental treatment on the environment.

Results

The study consisted of 1267 participants. Participants were mostly female, older, employed and mainly of African descent. Participants reported a very positive attitude towards sustainable dentistry (Mean = 3.89, SD = 0.8). and were moderately willing to accept alternatives such as a longer appointment time (Mean 3.47, SD = 0.73) and pay more for their dental treatments (Mean=3.00, SD = 0.87). There was a strong positive correlation with attitudes to sustainable dentistry and participants willingness to accept alternatives such as a longer appointment time (r = 0.658, p < 0.05).

Conclusion

The adult population had an overall positive attitude towards sustainable dentistry and was willing to accept alternatives so that their dental treatment would have less impact on the environment.

导言:特立尼达和多巴哥对可持续牙科治疗替代品的态度和接受意愿从未进行过评估。市场研究有助于了解人们的行为。由于变革可以通过公众压力来实现,因此值得通过研究让公众参与进来,以了解他们的态度以及他们愿意接受哪些变革。该问卷调查了人们对减少牙科治疗对环境影响的替代方法的态度和接受意愿。参与者大多为女性,年龄较大,有工作,主要是非洲裔。参与者对可持续牙科治疗持非常积极的态度(平均值=3.89,标准差=0.8),并在一定程度上愿意接受延长预约时间(平均值=3.47,标准差=0.73)和支付更多牙科治疗费用(平均值=3.00,标准差=0.87)等替代方案。对可持续牙科治疗的态度与参与者接受延长预约时间等替代方案的意愿之间存在很强的正相关性(r = 0.658, p < 0.05)。
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引用次数: 0
Pure rotation in the temporomandibular joint during jaw opening? A digital motion analysis 下颌打开时颞下颌关节的纯旋转?数字运动分析
IF 3 Q2 Dentistry Pub Date : 2024-04-18 DOI: 10.1038/s41405-024-00213-8
Bálint Jász, Tamás Balogh, Szilvia Ambrus, Péter Schmidt, Gréta Lilla Bányai, Szandra Körmendi, Máté Jász

Objective

In the temporomandibular joint two separate movements of rotation and translation occur in two articular spaces during mouth opening. Over the years, the approach has changed considerably, but it is still subject to controversy as to which of these movement is involved in the initial stage of mouth opening. In the present study, the extent of rotation and translation was investigated in the first 5 mm of mouth opening.

Materials and methods

The study was carried out on 46 volunteers. Anamnesis was taken and patients were examined. For the investigation, an ultrasonic digital motion analyser (KaVo Arcus Digma 2) was applied. The measurements were made after calibration to an arbitrary axis. Each participant performed three open-close movements in succession, starting from maximum intercuspal position.

Results

Data were statistically processed using cubic spline interpolation. Linear regression was then used. The resulting line is significantly (p < 0.0001) different from the horizontal that represents only rotational movement.

Conclusion

The results show that during mouth opening from maximum intercuspal position, translation is present continuously in addition to rotation. Therefore, it might be time to re-evaluate the principle of a pure rotational approach.

目的 在张口过程中,颞下颌关节的两个关节间隙分别发生旋转和平移运动。多年来,研究方法已发生了很大变化,但在张口的初始阶段,这两种运动中的哪一种仍存在争议。本研究调查了张口最初 5 毫米处的旋转和平移程度。对 46 名志愿者进行了研究,采集了他们的病史并对他们进行了检查。调查中使用了超声波数字运动分析仪(KaVo Arcus Digma 2)。测量是在对任意轴进行校准后进行的。每位受试者从最大趾间位置开始,连续进行三次开合运动。然后使用线性回归。结果表明,从最大趾间位置开始张口时,除了旋转外,平移也持续存在。因此,也许是时候重新评估纯旋转方法的原则了。
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引用次数: 0
The ability of different compositions of calcium silicate and epoxy sealers to withstand gutta percha removal via in vitro pull-out testing 通过体外拉出试验,测试不同成分的硅酸钙和环氧树脂密封剂耐受古塔胶去除的能力
IF 3 Q2 Dentistry Pub Date : 2024-04-08 DOI: 10.1038/s41405-024-00212-9
Idan Stiklaru, Ella Lalum, Sobhi Hamoud, Maayan Paz, Avi Levin, Joe Ben Itzhak, Nirit Yavnai, Pavel Gorenbein, Michael Solomonov

Objective

examination of the influence of chemical composition changes on the ability of sealers to withstand a pull-out test.

Materials and methods

Fifty distal or palatal canals of extracted teeth were prepared by Dc Taper files. The teeth were divided into five groups: AH Plus, BJM RCS, Total Fill BC,AH Plus Bioceramic and a group with Gutta Percha with no sealer added. Ten days after obturation, each cone was subjected to the “pull-out test” with the Shimadzo Universal Testing Machine until it was torn or removed from the canal. A force to Stroke graph was generated and the maximum vertex of this graph was recorded. The number of times the cone was torn or removed was recorded.

Results

The amount of force needed to remove or rupture the cone was significantly higher in all sealer groups compared to the AH Plus Bioceramic group. The force needed for the AH Plus group was double that needed for the AH Plus Bioceramic group 4 (1.87 ± 0.53 N vs 0.93 ± 0.48 N, respectively, P < 0.001). All of the cones (n = 10) in the AH Plus Bio Ceramic Sealer group were removed in their entirety (P = 0.01 compared to each of the other groups).

Conclusions

The addition of macromolecules to epoxy sealer does not change the material’s ability to withstand the pull-out test. Decreasing the amount of tri- and di-calcium silicate compounds combined with increasing amounts of zirconium oxide in a Bioceramic sealer significantly decreased the material’s ability to withstand the pull-out test.

材料和方法用 Dc 锥形锉制备 50 个拔牙远端或腭管。这些牙齿被分为五组:AH Plus组、BJM RCS组、Total Fill BC组、AH Plus Bioceramic组和未添加封闭剂的Gutta Percha组。封闭十天后,使用岛津万能试验机对每个锥体进行 "拔出试验",直到锥体被撕裂或从牙道中拔出。生成力-行程图,并记录该图的最大顶点。结果与 AH Plus 生物陶瓷组相比,所有封闭剂组移除或破裂锥体所需的力都明显较高。AH Plus 组所需的力是 AH Plus 生物陶瓷 4 组的两倍(分别为 1.87 ± 0.53 N vs 0.93 ± 0.48 N,P < 0.001)。AH Plus 生物陶瓷密封剂组中的所有锥体(n = 10)都被全部拔出(与其他各组相比,P = 0.01)。在生物陶瓷封闭剂中减少三硅酸钙和二硅酸钙化合物的用量,同时增加氧化锆的用量,会显著降低材料的抗拉测试能力。
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引用次数: 0
Signaling pathways of dental implants’ osseointegration: a narrative review on two of the most relevant; NF-κB and Wnt pathways 牙科植入物骨结合的信号通路:对两种最相关通路(NF-κB 和 Wnt 通路)的叙述性综述
IF 3 Q2 Dentistry Pub Date : 2024-04-05 DOI: 10.1038/s41405-024-00211-w
Samar Mohamed Emam, Nermine Moussa

Introduction

Cell signaling pathways are the biological reactions that control cell functions and fate. They also directly affect the body reactions to implanted biomaterials. It is well-known that dental implants success depends on a successful integration with the alveolar bone: “osseointegration” which events comprise early and later responses to the implanted biomaterials. The early events are mainly immune-inflammatory responses to the implant considered by its microenvironment as a foreign body. Later reactions are osteogenic aiming to regulate bone formation and remodeling. All these events are controlled by the cell signaling pathways in an incredible harmonious coordination.

Aim

The number of pathways having a role in osseointegration is so big to be reviewed in a single article. So the aim of this review was to study only two of the most relevant ones: the inflammatory Nuclear Factor Kappa B (NF-κB) pathway regulating the early osseointegration events and the osteogenic Wnt pathway regulating later events.

Methods

We conducted a literature review using key databases to provide an overview about the NF-κB and Wnt cell signaling pathways and their mutual relationship with dental implants. A simplified narrative approach was conducted to explain these cell signaling pathways, their mode of activation and how they are related to the cellular events of osseointegration.

Results and conclusion

NF-κB and Wnt cell signaling pathways are important cross-talking pathways that are affected by the implant’s material and surface characteristics. The presence of the implant itself in the bone alters the intracellular events of both pathways in the adjacent implant’s cellular microenvironment. Both pathways have a great role in the success or failure of osseointegration. Such knowledge can offer a new hope to treat failed implants and enhance osseointegration in difficult cases. This is consistent with advances in Omics technologies that can change the paradigm of dental implant therapy.

导言细胞信号通路是控制细胞功能和命运的生物反应。它们也直接影响人体对植入生物材料的反应。众所周知,牙科植入物的成功取决于与牙槽骨的成功结合:"骨结合 "包括对植入生物材料的早期和后期反应。早期反应主要是针对被微环境视为异物的种植体的免疫炎症反应。后期反应是成骨反应,旨在调节骨形成和重塑。所有这些事件都是由细胞信号通路控制的,它们之间的协调关系令人难以置信。因此,这篇综述的目的只是研究其中两个最相关的途径:调节早期骨结合事件的炎症性核因子卡巴B(NF-κB)途径和调节后期事件的成骨性Wnt途径。结果和结论NF-κB和Wnt细胞信号通路是重要的交叉对话通路,会受到种植体材料和表面特性的影响。种植体本身在骨中的存在会改变邻近种植体细胞微环境中这两种通路的细胞内事件。这两种途径对骨结合的成败起着重要作用。这些知识为治疗失败的种植体和增强疑难病例的骨结合提供了新的希望。这与 Omics 技术的进步是一致的,它可以改变牙科种植治疗的模式。
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引用次数: 0
The demineralization resistance and mechanical assessments of different bioactive restorative materials for primary and permanent teeth: an in vitro study 原牙和恒牙用不同生物活性修复材料的抗脱矿能力和力学评估:体外研究
IF 3 Q2 Dentistry Pub Date : 2024-04-05 DOI: 10.1038/s41405-024-00209-4
Maria Salem Ibrahim, Fahad Rakad Aldhafeeri, Abdullah Sami Banaemah, Mana S. Alhaider, Yousif A. Al-Dulaijan, Abdulrahman A. Balhaddad

Objectives

This article examines the efficacy of two bioactive dental composites in preventing demineralization while preserving their mechanical and physical properties.

Materials and methods

The study compares Beautifil Kids and Predicta® Bioactive Bulk-Fill (Predicta) composites with conventional dental composite. Flexural strength and elastic modulus were evaluated using a universal testing machine. A pH-cycling model assessed the composites’ ability to prevent dentin demineralization. Color stability and surface roughness were measured using a spectrophotometer and non-contact profilometer, respectively, before and after pH-cycling, brushing simulation, and thermocycling aging.

Results

Beautifil Kids exhibited the highest flexural strength and elastic modulus among the materials (p < 0.05). Predicta demonstrated the highest increase in dentin surface microhardness following the pH-cycling model (p < 0.05). All groups showed clinically significant color changes after pH-cycling, with no significant differences between them (p > 0.05). Predicta exhibited greater color change after brushing and increased surface roughness after thermocycling aging (p < 0.05). While Beautifil Kids had higher surface roughness after pH-cycling (p < 0.05).

Discussion/Conclusion

Bioactive restorative materials with ion-releasing properties demonstrate excellent resistance to demineralization while maintaining mechanical and physical properties comparable to the control group.

材料和方法该研究比较了 Beautifil Kids 和 Predicta® Bioactive Bulk-Fill (Predicta) 复合材料与传统牙科复合材料。使用万能试验机评估了弯曲强度和弹性模量。pH 循环模型评估了复合材料防止牙本质脱矿的能力。在 pH 循环、模拟刷牙和热循环老化前后,分别使用分光光度计和非接触式轮廓仪测量了颜色稳定性和表面粗糙度。在 pH 循环模型中,Predicta 表现出牙本质表面微硬度的最高增幅(p < 0.05)。所有组别在 pH 循环后都出现了明显的临床颜色变化,但组间差异不大(p > 0.05)。Predicta 在刷牙后颜色变化更大,在热循环老化后表面粗糙度增加(p < 0.05)。讨论/结论具有离子释放特性的生物活性修复材料在保持与对照组相当的机械和物理特性的同时,还表现出卓越的抗脱矿性。
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引用次数: 0
Knowledge and attitudes toward anaphylaxis to local anesthetics in dental practice 牙科医生对局部麻醉剂过敏性休克的认识和态度
IF 3 Q2 Dentistry Pub Date : 2024-04-04 DOI: 10.1038/s41405-024-00210-x
Ivan Cherrez-Ojeda, Juan C. Gallardo-Bastidas, Gabriela Rouillon Borrero, Hans Mautong, Paola Andrea Mena Silva, Zouina Sarfraz, Azza Sarfraz, Leonardo Cano, Karla Robles-Velasco

Objective/aim

The absence of a comprehensive understanding of potential anaphylactic reactions to local anesthetics (LAs) and management can result in grave consequences. For this reason we aim to assess Latin American dentists’ knowledge, preparedness, and competency in managing anaphylactic reactions to LAs.

Materials and Methods

Design: A cross-sectional study was conducted from November 2021 to February 2022. Board-certified dentists answered a survey comprising 26 structured questions. Chi-square tests and logistic regression models were performed in Stata 17.0. Setting: Argentina, Brazil, Colombia, Costa Rica, Ecuador, Honduras, Mexico, Peru, Venezuela, and other Latin American countries.

Results

Of 507 respondents, lidocaine was the most frequently used LA (88.1%). While 85.2% could identify dyspnea as a symptom of anaphylaxis, only 50.1% knew the correct route for epinephrine administration, and just 43.5% had epinephrine in their emergency kits. Confidence in managing anaphylactic reactions was low (9.6%). Older age was inversely related to both knowledge of anaphylaxis management and the possession of epinephrine (P = 0.003 and P = 0.0001, respectively).

Discussion

Our study highlights a concerning discrepancy between the practical readiness of Latin American dentists in handling anaphylaxis.

Conclusion

The study’s findings underscore the need for educational interventions to improve the readiness to identify and handle anaphylactic emergencies in dental practice.

目的/意义如果对局部麻醉剂(LAs)可能引起的过敏反应及处理缺乏全面了解,可能会导致严重后果。因此,我们旨在评估拉丁美洲牙医在处理局麻药过敏反应方面的知识、准备情况和能力:我们于 2021 年 11 月至 2022 年 2 月开展了一项横断面研究。通过认证的牙科医生回答了由 26 个结构化问题组成的调查问卷。在 Stata 17.0 中进行了卡方检验和逻辑回归模型。研究地点结果 在 507 位受访者中,利多卡因是最常用的 LA(88.1%)。虽然 85.2% 的受访者能将呼吸困难确定为过敏性休克的症状,但只有 50.1% 的受访者知道肾上腺素的正确给药途径,只有 43.5% 的受访者的应急包中有肾上腺素。对处理过敏性反应的信心不足(9.6%)。年龄与过敏性休克处理知识和肾上腺素的拥有量成反比(分别为 P = 0.003 和 P = 0.0001)。
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引用次数: 0
Unveiling motives for dentistry studies: psychometric validation of a comprehensive questionnaire among aspiring dental students. 揭示牙科学研究的动机:在有抱负的牙科学生中对综合问卷进行心理测量验证。
IF 3 Q2 Dentistry Pub Date : 2024-03-28 DOI: 10.1038/s41405-024-00208-5
Jorge Moncayo-Rizzo, Geovanny Alvarado-Villa, Iván Cherrez-Ojeda, Juan Carlos Gallardo, Eleonor Velez Leon, Susana Patricia Gonzalez Eras

Objective: The aim of this study is to develop and validate a questionnaire for dental students in Ecuador to assess their reasons to study dentistry.

Materials and methods: A 25-item questionnaire was developed by the authors based on similar studies and a qualitative study. The questionnaire had five theoretical factors: economic, professional, vocational, social and academic reasons for study. In the first two samples, exploratory factor analysis was performed to identify the structure, and the models obtained were compared with confirmatory factor analysis in the third sample.

Results: Three samples were used, sample A with 201 participants, sample B with 623 participants, and sample C with 596 participants. Two-thirds of the participants were female and almost one-third were from coast region. The EFA applied in sample A resulted in a five-factor model with 18 items; in contrast, a three-factor model was obtained from sample B. According to the CFA in sample C, the best model was explained by three factors: labor, vocational and academic reasons. Considering two items to cross-load in labor and vocational factors, which are theoretically justified.

Conclusion: This study presents a 12-item questionnaire that assesses labor, vocational and academic reasons for studying dentistry in an Ecuadorian population.

研究目的本研究的目的是为厄瓜多尔的牙科学生制定并验证一份问卷,以评估他们学习牙科的原因:作者在类似研究和定性研究的基础上编制了一份 25 个项目的调查问卷。问卷包含五个理论因素:学习的经济、专业、职业、社会和学术原因。在前两个样本中,进行了探索性因子分析以确定结构,在第三个样本中,将得到的模型与确认性因子分析进行了比较:共使用了三个样本,样本 A 有 201 名参与者,样本 B 有 623 名参与者,样本 C 有 596 名参与者。三分之二的参与者为女性,近三分之一来自沿海地区。在样本 A 中进行的 EFA 得出了一个包含 18 个项目的五因素模型;而在样本 B 中则得出了一个三因素模型。考虑到劳动因素和职业因素中有两个项目交叉负载,这在理论上是合理的:本研究提供了一份 12 个项目的调查问卷,用于评估厄瓜多尔人口学习牙科的劳动、职业和学术原因。
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引用次数: 0
Attitude and performance in controlling dust particles from dental prosthesis and appliance adjustment: a survey of dentists and dental assistants. 对牙科医生和牙科助理进行的一项调查:牙科医生和牙科助理在控制来自牙科修复体和器具调整的尘埃微粒方面的态度和表现。
IF 3 Q2 Dentistry Pub Date : 2024-03-20 DOI: 10.1038/s41405-024-00206-7
Nareudee Limpuangthip, Prarom Salimee, Phanomporn Vanichanon

Objectives: To assess the attitude and practices of dentists and dental assistants in managing dust particles generated during dental prostheses or appliances grinding and polishing.

Materials and methods: Data were collected from 207 dentists and 125 dental assistants through an online questionnaire. The questionnaire included adjusted prosthesis types, self-protective methods, types and frequency of protective device use, and reasons for non-frequent use.

Results: Protective grinding devices, including dust protective boxes and mounted plastic sheets, were commonly used for substantial acrylic resin adjustments, while air blowing was preferred for minor adjustments. Post-COVID-19, there was a 3-fold increase in the use of protective grinding devices among dentists and a 1.3-fold increase among dental assistants. During try-in procedures, dentists commonly rinsed prostheses with water rather than using disinfectants. Non-frequent users adopted self-protection methods, such as face shields and air filters. Surgical drapes and high-volume evacuators were used for patient's protection.

Conclusion: Despite an increased tendency of the use of protective grinding devices following COVID-19, a significant number still report infrequent use. Identified protective devices in this study have drawbacks not fully meeting dentists' expectations. Invention of a more user-friendly device is necessary to ensure regular use, preventing potential toxicity from dust particles.

目的评估牙医和牙科助理在管理牙科修复体或器具研磨和抛光过程中产生的尘埃微粒方面的态度和做法:通过在线问卷收集了 207 名牙医和 125 名牙科助理的数据。问卷内容包括调整后的修复体类型、自我保护方法、保护装置的类型和使用频率,以及不经常使用的原因:结果:保护性打磨装置,包括防尘盒和安装的塑料板,常用于丙烯酸树脂的大幅调整,而吹气则是小幅调整的首选。COVID-19之后,牙医使用保护性打磨装置的比例增加了3倍,牙科助理增加了1.3倍。在试戴过程中,牙医通常用水冲洗义齿,而不是使用消毒剂。非经常使用者采用自我保护方法,如面罩和空气过滤器。为保护病人,还使用了手术帘和高容量排空器:尽管在 COVID-19 之后使用保护性磨削装置的趋势有所增加,但仍有相当多的人表示不经常使用。本研究中发现的保护装置存在一些缺点,不能完全满足牙医的期望。有必要发明一种更方便用户使用的装置,以确保定期使用,防止灰尘微粒的潜在毒性。
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引用次数: 0
Performance of self-cured versus light-cured universal adhesive in patients with non-carious cervical lesions: 18-month randomized clinical trial 自固化万能胶与光固化万能胶在非龋齿性宫颈病变患者中的应用效果:为期 18 个月的随机临床试验
IF 3 Q2 Dentistry Pub Date : 2024-03-19 DOI: 10.1038/s41405-024-00204-9
Aya Gamal Ashour, Rawda Hesham Abd ElAziz, Asmaa Ali Yassen

Objective

To evaluate the clinical performance of self versus light-cured universal adhesive in non-carious cervical lesions (NCCLs) after 18 months.

Materials and methods

Sixty-eight NCCLs in 28 patients were divided into two equal groups; G1: self-cured universal adhesive (Palfique,Tokuyama,Japan) and G2: light-cured universal adhesive (Single Bond Universal,3 M ESPE,USA). Nanohybrid resin composite (Z350XT, 3 M ESPE, USA) was used as a final restoration. Evaluation for fracture, loss of retention, marginal adaptation and discoloration were done after 1 week, 6,12, and 18 months using FDI criteria. Postoperative sensitivity was assessed after 1 week. Chi-Square and Mann-Whitney tests with statistical significance at (P ≤ 0.05) were used for intergroup comparison,while the intragroup one was performed using the Cochran’s Q and Friedman’s tests. Survival rate was analyzed using Kaplan-meier and Log-rank test.

Results

Both groups exhibited fracture and retention loss, however, there was statistically significant difference favoring the control group at 6 months (p = 0.0114,0.0016). For secondary outcomes, marginal adaptation and discoloration revealed no significant differences. For postoperative sensitivity, there was a significant difference favoring the control group (p = 0.0007, 0.0011). Palfique had 1.5 Relative-Risk (RR) after 6 months (95% CI 0.5659–4.2617; P = 0.3928) and 20% less risk of failure after 18 months (RR 0.8) (95% CI 0.4618–1.3858; P = 0.4260). Tested adhesives showed equal survival rate (P = 0.5685).

Conclusions

Both adhesives revealed similar clinical performance in restoring the NCCLs after 18 m, however, the early failure was more frequent in the self-cured universal adhesive.

材料和方法将 28 名患者的 68 个非龋性颈椎病(NCCL)分为两组:G1:自固化万能粘接剂(Palfique,日本德山);G2:光固化万能粘接剂(Single Bond Universal,美国 3 M ESPE)。纳米杂化树脂复合材料(Z350XT,3 M ESPE,美国)用作最终修复体。根据 FDI 标准,在 1 周、6、12 和 18 个月后对断裂、固位丧失、边缘适应和变色进行评估。术后敏感度在 1 周后进行评估。组间比较采用 Chi-Square 检验和 Mann-Whitney 检验,统计学意义为(P ≤ 0.05),组内比较采用 Cochran's Q 检验和 Friedman's 检验。结果 两组均有骨折和潴留损失,但对照组在 6 个月时的差异有统计学意义(P = 0.0114,0.0016)。在次要结果方面,边缘适应性和变色无明显差异。在术后敏感度方面,对照组有显著差异(p = 0.0007,0.0011)。Palfique 6 个月后的相对风险 (RR) 为 1.5(95% CI 0.5659-4.2617;P = 0.3928),18 个月后的失败风险降低 20%(RR 0.8)(95% CI 0.4618-1.3858;P = 0.4260)。结论两种粘合剂在 18 个月后恢复 NCCL 的临床表现相似,但自固化通用粘合剂的早期失败率更高。
{"title":"Performance of self-cured versus light-cured universal adhesive in patients with non-carious cervical lesions: 18-month randomized clinical trial","authors":"Aya Gamal Ashour, Rawda Hesham Abd ElAziz, Asmaa Ali Yassen","doi":"10.1038/s41405-024-00204-9","DOIUrl":"https://doi.org/10.1038/s41405-024-00204-9","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objective</h3><p>To evaluate the clinical performance of self versus light-cured universal adhesive in non-carious cervical lesions (NCCLs) after 18 months.</p><h3 data-test=\"abstract-sub-heading\">Materials and methods</h3><p>Sixty-eight NCCLs in 28 patients were divided into two equal groups; G1: self-cured universal adhesive (Palfique,Tokuyama,Japan) and G2: light-cured universal adhesive (Single Bond Universal,3 M ESPE,USA). Nanohybrid resin composite (Z350XT, 3 M ESPE, USA) was used as a final restoration. Evaluation for fracture, loss of retention, marginal adaptation and discoloration were done after 1 week, 6,12, and 18 months using FDI criteria. Postoperative sensitivity was assessed after 1 week. Chi-Square and Mann-Whitney tests with statistical significance at (<i>P</i> ≤ 0.05) were used for intergroup comparison,while the intragroup one was performed using the Cochran’s Q and Friedman’s tests. Survival rate was analyzed using Kaplan-meier and Log-rank test.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Both groups exhibited fracture and retention loss, however, there was statistically significant difference favoring the control group at 6 months (<i>p</i> = 0.0114,0.0016). For secondary outcomes, marginal adaptation and discoloration revealed no significant differences. For postoperative sensitivity, there was a significant difference favoring the control group (<i>p</i> = 0.0007, 0.0011). Palfique had 1.5 Relative-Risk (RR) after 6 months (95% CI 0.5659–4.2617; <i>P</i> = 0.3928) and 20% less risk of failure after 18 months (RR 0.8) (95% CI 0.4618–1.3858; <i>P</i> = 0.4260). Tested adhesives showed equal survival rate (<i>P</i> = 0.5685).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>Both adhesives revealed similar clinical performance in restoring the NCCLs after 18 m, however, the early failure was more frequent in the self-cured universal adhesive.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140167076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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