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Prospective controlled study comparing 5.5-mm long implants with longer implants to support fixed partial prosthesis in the premolar-molar regions: 12 months follow-up. 前瞻性对照研究比较5.5 mm长种植体与较长种植体在前磨牙区支持固定部分假体:12个月随访。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-17 DOI: 10.1038/s41405-025-00392-y
Eduardo Anitua, Adriana Montalvillo, Mohammad Hamdan Alkhraisat

Aim: This prospective controlled clinical study aimed at evaluating the performance of 5.5 mm-long implants to support two-unit fixed prosthesis in the posterior regions of the mandible and the maxilla.

Materials and methods: A total of 44 patients (30 females and 14 males) were included and received 51 test implants (5.5 mm in length) and 51 control implants (≥6.5 mm in length) to support two-unit fixed partial prosthesis in the mandible and the maxilla. Intermediate abutment was used in all cases. The patients were followed for 12 months. Changes in the marginal bone loss, implant survival, and prosthetic complications were compared between the two groups.

Results: The patient's mean age was 64 years (range: 42-48 years). All the implants in the test group were placed at the molars site compared to 26 implants in the control group (p < 0.001). Bone type (p = 0.224) and insertion torque (p = 0.671) were similar between the groups. None of the implants failed. The changes in marginal bone level at mesial (median: 0.3 mm; range: -1.3 to 2.9 mm for control, and 0.2 mm; -0.7 to 1.6 mm for test; p = 0.138) and at distal (median: 0.3 mm; range: -1.3 to 1.5 mm for control, and 0.2 mm; -1.2 to 1.4 mm for test; p = 0.0633) were similar between the study groups. The prostheses were free of technical complications.

Conclusions: This prospective controlled clinical study supports the use of 5.5-mm long implants in the context of fixed partial prosthesis and posterior regions. No statistically significant differences have been observed in marginal bone stability, implant survival and prosthetic complications compared to longer implants. Within the limits of this study, 5.5 mm implants appear to be a predictable option for fixed posterior partial dentures.

目的:本前瞻性对照临床研究旨在评估5.5 mm长种植体在下颌和上颌骨后区支持双单元固定假体的性能。材料与方法:共纳入44例患者(女性30例,男性14例),分别植入51个长度为5.5 mm的试验种植体和51个长度≥6.5 mm的对照种植体,用于支持下颌和上颌骨的两单元固定部分假体。所有病例均采用中间基台。随访12个月。比较两组间边缘骨丢失、种植体存活和假体并发症的变化。结果:患者平均年龄64岁(范围42 ~ 48岁)。与对照组26颗种植体相比,试验组所有种植体均放置在磨牙部位(p)。结论:本前瞻性对照临床研究支持在固定部分假体和后牙区域的情况下使用5.5 mm长的种植体。与较长的种植体相比,在边缘骨稳定性、种植体存活和假体并发症方面没有统计学上的显著差异。在本研究的范围内,5.5 mm种植体似乎是固定后牙部分义齿的可预测选择。
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引用次数: 0
Evaluation of the antibacterial efficacy of diode laser and zinc oxide nanoparticles as cavity disinfectants following partial caries removal: a randomized controlled clinical trial. 评价二极管激光和氧化锌纳米颗粒作为部分龋齿清除后的口腔消毒剂的抗菌效果:一项随机对照临床试验
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-16 DOI: 10.1038/s41405-025-00373-1
Sarah Khattab, Rasha Raafat, Mona Riad
<p><strong>Background: </strong>Dental caries remains one of the most common chronic conditions worldwide, often requiring treatment that balances effective bacterial control with preservation of healthy tooth structure. In recent years, researchers have explored novel antimicrobial approaches that can be used during minimally invasive caries treatments. Various adjunctive methods have been employed to inhibit the growth of residual bacteria in deep carious lesions. While chemical disinfectants have demonstrated notable antibacterial properties, their effectiveness can be compromised by some side effects, including adverse interactions with restorative materials and potential alterations to dental tissue structure. Consequently, there is a growing need for alternative antibacterial approaches. Among the latest advancements in cavity disinfection are diode lasers and zinc oxide nanoparticles.</p><p><strong>Aim: </strong>Considering the limited number of clinical studies investigating both agents as cavity disinfectants, the primary aim of the present clinical trial was to evaluate the antibacterial effectiveness of a diode laser (976 nm) and zinc oxide nanoparticles in an ethanol-based solution against cariogenic bacteria, specifically Streptococcus mutans, when applied as cavity disinfectants.</p><p><strong>Materials and methods: </strong>Thirty patients with deep cervical carious lesions were randomized into two groups (n = 15). After selective caries removal, baseline carious dentin samples were collected (control). One group received cavity disinfection using a 976 nm diode laser at 1.3 W output, while the other was treated with zinc oxide nanoparticles (50 μg/mL ethanol-based solution). Zinc oxide nanoparticles were prepared and characterized using transmission electron microscopy and X-ray diffraction to confirm morphology and crystallinity. Post-intervention dentin samples were collected via colony-forming units (CFU) for microbiological analysis.</p><p><strong>Results: </strong>Transmission electron microscopy revealed spherical zinc oxide nanoparticles with diameters averaging 18 nm. X-Ray diffraction confirmed high crystallinity. Both the laser diode and zinc oxide nanoparticles groups showed significant reductions in colony forming unit post-disinfection (p < 0.001). The diode laser group had significantly higher colony forming unit (mean: 8.27 ± 0.80 CFU/mL) compared to the zinc oxide nanoparticles group (mean: 3.47 ± 0.74 CFU/mL). Percentage of bacterial reduction was lower in the laser diode group (93.77%) than the ZnO NPs group (97.4%).</p><p><strong>Conclusion: </strong>Spherical-shaped zinc oxide nanoparticles with particle sizes around 25 nm and 50 μg/mL concentration in ethanol-based solution demonstrated superior antibacterial efficacy, suggesting they are a promising alternative for cavity disinfection in conservative caries management.</p><p><strong>Clinical significance: </strong>The results of the trial open new possibiliti
背景:龋齿仍然是世界范围内最常见的慢性疾病之一,通常需要在有效控制细菌和保持健康牙齿结构之间取得平衡的治疗。近年来,研究人员探索了可用于微创龋齿治疗的新型抗菌方法。各种辅助方法已被用于抑制深部龋齿病变中残留细菌的生长。虽然化学消毒剂已经显示出显著的抗菌性能,但它们的有效性可能会受到一些副作用的影响,包括与修复材料的不良相互作用和对牙齿组织结构的潜在改变。因此,对替代抗菌方法的需求日益增长。在腔消毒的最新进展是二极管激光和氧化锌纳米颗粒。目的:考虑到将这两种药物作为口腔消毒剂的临床研究数量有限,本临床试验的主要目的是评估二极管激光(976 nm)和氧化锌纳米颗粒在乙醇基溶液中作为龋齿细菌,特别是变形链球菌作为口腔消毒剂时的抗菌效果。材料与方法:将30例宫颈深部病变患者随机分为两组(n = 15)。选择性除龋后,收集基线蛀牙本质样本(对照组)。其中一组采用输出功率为1.3 W的976 nm二极管激光器进行腔消毒,另一组采用氧化锌纳米颗粒(50 μg/mL乙醇基溶液)进行消毒。制备了氧化锌纳米颗粒,并用透射电子显微镜和x射线衍射对其形貌和结晶度进行了表征。通过菌落形成单位(CFU)收集干预后牙本质样本进行微生物学分析。结果:透射电镜显示球形氧化锌纳米颗粒,平均直径为18 nm。x射线衍射证实结晶度高。结论:粒径在25 nm左右、浓度为50 μg/mL的球形氧化锌纳米颗粒在乙醇溶液中具有较好的抗菌效果,是保守性龋齿治疗的一种有前景的口腔消毒选择。临床意义:该试验结果通过将更有针对性和保守的消毒方案纳入日常牙科实践,为改善患者预后开辟了新的可能性。临床试验注册:本研究在临床试验上注册(www.Clinicaltrials: gov)。
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引用次数: 0
A survey on providers' views on utilization of dental hygienists and dental therapists delivering periodontal care in the South West of England. 一项调查提供者的意见利用牙科保健师和牙科治疗师提供牙周护理在英格兰西南部。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-16 DOI: 10.1038/s41405-025-00372-2
Cher Farrugia, Janita Dhariwal, Chris Bell, Ana Beatriz Oliveira Gambôa

Aim: To examine the opportunities and limitations for dental hygienists and therapists (DCPs) delivering periodontal care in primary care settings.

Materials and methods: A cross-sectional survey was conducted among primary care dental providers in the South West of England following University of Bristol ethical approval (number 15281). The survey assessed the current providers' views on utilization of DCPs, including availability, their practice, direct access and provider perspectives on referrals and remuneration.

Results: Thirty-one providers participated, with 30(97%) offering both NHS and private services and 1(3%) private only. Twenty-eight providers (90%) employed a DCP, primarily a hygienist (n = 23,82%). While all providers referred patients to DCPs, 18 (64%) referred only for private care. Three (11%) provided NHS direct access, compared to 18 (64%) for private, citing financial and workload barriers. Remuneration methods varied, with percentage split (n = 16,57%) being most common. Over half of the respondents (n = 18,58%) felt NHS use of DCPs was unfeasible, and 21(68%) doubted that NHS contract reforms would improve DCP employment opportunities.

Conclusion: Current NHS contracts may not sufficiently support DCP involvement in NHS periodontal care, indicating the need for contract reform to facilitate their broader use.

目的:研究初级保健机构牙科保健师和治疗师(dcp)提供牙周保健的机会和局限性。材料和方法:在布里斯托尔大学伦理批准(编号15281)之后,在英格兰西南部的初级保健牙科提供者中进行了横断面调查。调查评估了目前供应商对dcp利用的看法,包括可获得性、他们的做法、直接获取和供应商对转诊和薪酬的看法。结果:31家供应商参与,其中30家(97%)同时提供NHS和私人服务,1家(3%)仅提供私人服务。28家医疗服务提供者(90%)雇用了一名DCP,主要是一名卫生员(n = 23,82%)。虽然所有的提供者都将患者转介给dcp,但18(64%)只转介给私人护理。3家(11%)提供NHS直接服务,相比之下,18家(64%)提供私人服务,理由是财务和工作量障碍。薪酬方法各不相同,最常见的是百分比分配(n = 16.57%)。超过一半的受访者(n = 18,58%)认为NHS使用DCP是不可行的,21(68%)怀疑NHS合同改革将改善DCP的就业机会。结论:目前的NHS合同可能不足以支持DCP参与NHS牙周保健,表明需要进行合同改革以促进其更广泛的使用。
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引用次数: 0
Evaluation of potential sources of nosocomial infection in endodontic practice: a hygienic study. 牙髓治疗中潜在医院感染源的评估:一项卫生研究。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-12 DOI: 10.1038/s41405-025-00378-w
Stanislav Voroshilov, Baghish Harutyunyan, Vigen Goginyan, Michael Solomonov

Aim: This hygienic study assesses the microbial contamination of objects commonly used in a clinic during routine endodontic procedures.

Methods: Samples were collected from clinical surfaces and instruments. Microbial colonies were cultured on agar, enumerated, and identified phenotypically, including assessment of antibiotic resistance.

Results and conclusions: Findings revealed that the majority of objects in routine endodontic practice are predominantly contaminated by skin-derived Staphylococcus epidermidis and Micrococcus luteus, which frequently exhibit antibiotic resistance, whilst Stenotrophomonas maltophilia is also a frequent contaminant, particularly in DUWL. Other items, including rubber dam sheets, gloves, paper points, and paper mixing pads, showed detectable microbial contamination. These results highlight the presence of potentially nosocomial microorganisms on routine endodontic surfaces, emphasising the importance of appropriate hygiene measures in endodontic practice.

目的:本卫生研究评估临床常规牙髓治疗过程中常用物品的微生物污染。方法:从临床表面和器械上采集标本。在琼脂上培养微生物菌落,枚举并鉴定表型,包括评估抗生素耐药性。结果和结论:研究结果显示,在常规牙髓治疗中,大多数对象主要被皮肤源性表皮葡萄球菌和黄体微球菌污染,这些细菌经常表现出抗生素耐药性,而嗜麦芽窄养单胞菌也是常见的污染物,特别是在DUWL中。其他物品,包括橡胶坝板、手套、纸尖和纸搅拌垫,显示出可检测到的微生物污染。这些结果强调了常规根管表面存在潜在的医院微生物,强调了在根管实践中采取适当卫生措施的重要性。
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引用次数: 0
Yoga for myofascial pain of masticatory muscles - a development and feasibility study. 瑜伽治疗咀嚼肌筋膜疼痛的发展与可行性研究。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-10 DOI: 10.1038/s41405-025-00377-x
Priya Thimma Ravindranath, Iven Klineberg, Manish Bhutada

Objective: Myofascial pain of masticatory muscles or jaw muscle pain, a common component of temporomandibular disorders (TMD) often comes with substantial burden and high healthcare expenses. The aim of this study is to evaluate the feasibility and acceptability of yoga in students experiencing myofascial pain.

Methods: Prospective participants were identified through jaw health screening. 25 students diagnosed with myofascial pain (Research Diagnostic Criteria for TMDs) volunteered for this randomized controlled study. Participants were randomized to one of two interventions for 28 days: either a yoga-inclusive management programme or an active control standard care. The clinical assessors were unaware of the assigned intervention. The primary outcomes were feasibility (adherence) and acceptability (perceived helpfulness and willingness to continue). Secondary exploratory outcomes included pain intensity and distribution, jaw function, oral health-related quality of life, psychosocial measures, and clinician-assessed palpation tenderness.

Results: 18 (8 yoga; 10 controls) participants completed the study. Adherence was significantly higher in the yoga group (85%) compared with controls (68%, p = 0.048). Yoga participants rated greater perceived benefit (mean 6.3 vs 3.0, p = 0.030) and all expressed willingness to continue beyond the study (vs 50% of controls). Exploratory analyses suggested within-group improvements in pain distribution, jaw function, and pain catastrophizing in the yoga group, though between-group differences in clinical outcomes were not significant.

Conclusion: This study provides valuable preliminary insights into intervention's implementation and offers a foundation for future trials.

Clinical trial registration: This study was retrospectively registered with Australian New Zealand Clinical Trials Registry ( https://www.anzctr.org.au/ ) (Trial Id: ACTRN12623000069651).

目的:咀嚼肌筋膜疼痛或颚肌疼痛是颞下颌疾病(TMD)的常见组成部分,通常伴随着沉重的负担和高昂的医疗费用。本研究的目的是评估瑜伽对肌筋膜疼痛学生的可行性和可接受性。方法:通过颌骨健康筛查确定前瞻性参与者。25名被诊断为肌筋膜疼痛的学生自愿参加了这项随机对照研究。参与者被随机分配到两种干预措施中的一种,为期28天:要么是瑜伽管理计划,要么是积极对照标准护理。临床评估人员不知道指定的干预措施。主要结果是可行性(依从性)和可接受性(感知到的有用性和继续的意愿)。次要探索性结果包括疼痛强度和分布、颌功能、口腔健康相关生活质量、心理社会测量和临床评估的触诊压痛。结果:18名参与者(8名瑜伽者,10名对照组)完成了研究。瑜伽组的依从性(85%)明显高于对照组(68%,p = 0.048)。瑜伽参与者认为获益更大(平均6.3 vs 3.0, p = 0.030),并且所有参与者都表示愿意在研究结束后继续(对照50%)。探索性分析表明,瑜伽组在疼痛分布、颌功能和疼痛灾变方面有组内改善,但临床结果组间差异不显著。结论:本研究为干预措施的实施提供了有价值的初步见解,并为今后的试验奠定了基础。临床试验注册:本研究已在澳大利亚新西兰临床试验注册中心(https://www.anzctr.org.au/)回顾性注册(试验Id: ACTRN12623000069651)。
{"title":"Yoga for myofascial pain of masticatory muscles - a development and feasibility study.","authors":"Priya Thimma Ravindranath, Iven Klineberg, Manish Bhutada","doi":"10.1038/s41405-025-00377-x","DOIUrl":"10.1038/s41405-025-00377-x","url":null,"abstract":"<p><strong>Objective: </strong>Myofascial pain of masticatory muscles or jaw muscle pain, a common component of temporomandibular disorders (TMD) often comes with substantial burden and high healthcare expenses. The aim of this study is to evaluate the feasibility and acceptability of yoga in students experiencing myofascial pain.</p><p><strong>Methods: </strong>Prospective participants were identified through jaw health screening. 25 students diagnosed with myofascial pain (Research Diagnostic Criteria for TMDs) volunteered for this randomized controlled study. Participants were randomized to one of two interventions for 28 days: either a yoga-inclusive management programme or an active control standard care. The clinical assessors were unaware of the assigned intervention. The primary outcomes were feasibility (adherence) and acceptability (perceived helpfulness and willingness to continue). Secondary exploratory outcomes included pain intensity and distribution, jaw function, oral health-related quality of life, psychosocial measures, and clinician-assessed palpation tenderness.</p><p><strong>Results: </strong>18 (8 yoga; 10 controls) participants completed the study. Adherence was significantly higher in the yoga group (85%) compared with controls (68%, p = 0.048). Yoga participants rated greater perceived benefit (mean 6.3 vs 3.0, p = 0.030) and all expressed willingness to continue beyond the study (vs 50% of controls). Exploratory analyses suggested within-group improvements in pain distribution, jaw function, and pain catastrophizing in the yoga group, though between-group differences in clinical outcomes were not significant.</p><p><strong>Conclusion: </strong>This study provides valuable preliminary insights into intervention's implementation and offers a foundation for future trials.</p><p><strong>Clinical trial registration: </strong>This study was retrospectively registered with Australian New Zealand Clinical Trials Registry ( https://www.anzctr.org.au/ ) (Trial Id: ACTRN12623000069651).</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"11 1","pages":"94"},"PeriodicalIF":2.5,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12696018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145726119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Controversies about refrigeration of dental adhesives: a review. 关于口腔胶黏剂冷藏的争议综述。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-10 DOI: 10.1038/s41405-025-00379-9
Omar Abd El-Maksoud, Hamdi Hosni Hamdan Hamama, Ramy Ahmed Wafaie, Salah Hasab Mahmoud

Introduction: The refrigeration of dental adhesives is a routine practice, often adopted without thorough understanding or consideration of its scientific basis and potential clinical consequences. This review explores the effects of refrigeration and subsequent immediate use on the bonding effectiveness of dental adhesive systems. Given the ongoing debate in the literature about how storage temperature influences adhesive characteristics such as viscosity, degree of conversion, and bond strength, this work synthesizes findings from both supportive and contradictory studies to inform clearer clinical guidance.

Methods: Relevant literature was identified through a comprehensive search of key databases, including PubMed, Scopus, and Google Scholar, focusing primarily on in-vitro studies that investigated the effect of refrigeration on the bond strength and bonding-related kinetics of various adhesive systems: etch-and-rinse, self-etch, and universal adhesives.

Results: The collected data suggest that immediate use of adhesives post-refrigeration may induce material-dependent adverse changes in viscosity, solvent evaporation, and polymerization kinetics. These changes have primarily been linked to various factors that appear to critically mediate the influence of low temperature, including adhesive composition and solvent type. Although some studies have supported these findings, the anticipated deleterious effects could not be definitively confirmed, as several other investigations have reported negligible or no effects at all across different adhesive systems.

Conclusions: The heterogeneity of findings indicates that no conclusive agreement has been established regarding the actual risks associated with refrigerating dental adhesives. Nonetheless, the absence of evidence supporting any benefit from immediate post-refrigeration use suggests that allowing adhesives to reach room temperature before use remains a cautious and prudent approach.

口腔黏合剂的冷藏是一种常规做法,通常在没有充分了解或考虑其科学依据和潜在临床后果的情况下采用。这篇综述探讨了冷藏和随后立即使用对牙科粘合剂系统粘接效果的影响。鉴于文献中关于储存温度如何影响粘接剂特性(如粘度、转化程度和粘合强度)的持续争论,本工作综合了支持和矛盾研究的结果,以提供更清晰的临床指导。方法:通过对PubMed、Scopus和谷歌Scholar等关键数据库的全面检索,找到相关文献,主要关注制冷对各种胶粘剂体系(蚀蚀-漂洗、自蚀蚀和通用胶粘剂)粘接强度和粘接相关动力学的影响。结果:收集到的数据表明,冷冻后立即使用粘合剂可能会导致粘度、溶剂蒸发和聚合动力学等物质相关的不利变化。这些变化主要与各种因素有关,这些因素似乎对低温的影响起着关键的调节作用,包括粘合剂成分和溶剂类型。尽管一些研究支持这些发现,但预期的有害影响无法得到明确证实,因为其他一些研究报告在不同的粘合剂系统中几乎没有影响。结论:研究结果的异质性表明,关于冷冻牙粘接剂的实际风险尚未达成结论性协议。尽管如此,没有证据支持冷藏后立即使用的任何好处,这表明在使用前允许粘合剂达到室温仍然是一种谨慎和谨慎的方法。
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引用次数: 0
Aesthetic perception of maxillary incisor inclination in smiling profile of different facial divergences. 上颌门牙倾斜度对不同面部分度微笑轮廓的审美感知。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-08 DOI: 10.1038/s41405-025-00387-9
Mojgan Shavakhi, Amirmohammad Yavari, Kioumars Tavakoli Tafti

Objectives: This study aimed to evaluate the effect of maxillary incisor inclination on the aesthetic perception of the smiling profile in different facial divergences.

Materials and methods: A smiling profile photograph of a young woman was digitally altered to obtain three image series with different facial divergences. In each series, the inclination of the incisor teeth was changed in 5° intervals within a range of -15° to +15°. The 21 final images were submitted to 45 orthodontists and 45 laypeople to be rated based on the visual analogue scale.

Statistical analysis: The data were analysed with the independent t-test, repeated-measures ANOVA, and Pearson's correlation coefficient.

Results: The most attractive images for orthodontists were -5° in posterior divergence, 0° in neutral divergence and +10° in anterior divergence. While for laypeople, they were -10° in posterior divergence, 0° in neutral divergence and +5° in anterior divergence. In the posterior and anterior divergent faces, laypeople preferred more negative inclinations compared to orthodontists, but in all three faces, both groups chose the same inclinations as the most unattractive.

Conclusions: A harmony between the inclination of the maxillary incisor teeth and facial divergence leads to more aesthetic outcomes in such a way that in posterior divergence faces, negative inclinations, in anterior divergence faces, positive inclinations and in neutral divergence faces, incisors without inclination seemed to be more attractive. Also, laypeople tended to prefer more retroclined incisors than orthodontists.

目的:探讨上颌切牙倾斜度对不同面部分度下微笑轮廓美感的影响。材料与方法:对一名年轻女性的微笑侧面照片进行数字处理,得到三个不同面部差异的图像序列。在每个系列中,门牙的倾斜度在-15°到+15°的范围内以5°的间隔变化。最终的21幅图像被提交给45名正畸医生和45名外行人,根据视觉模拟量表进行评分。统计分析:采用独立t检验、重复测量方差分析和Pearson相关系数进行分析。结果:对正畸医师最具吸引力的图像为-5°后偏、0°中偏和+10°前偏。而对于外行人来说,后散度为-10°,中性散度为0°,前散度为+5°。在前后发散的面部中,外行人比正畸医生更喜欢消极的倾向,但在所有三张面部中,两组人都选择了最不吸引人的倾向。结论:上颌切牙的倾斜度与面部分度的协调可以获得更好的审美效果,在后分度面中,呈负向倾斜度,在前分度面中,呈正向倾斜度,在中性分度面中,无倾斜度的切牙更具吸引力。此外,外行人比正畸医生更喜欢后倾门牙。
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引用次数: 0
Triglycerides to high-density lipoprotein cholesterol ratio and its association with periodontitis-a systematic review. 甘油三酯与高密度脂蛋白胆固醇的比值及其与牙周炎的关系——系统综述。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-04 DOI: 10.1038/s41405-025-00381-1
Shashikiran Shanmugasundaram, Shaswata Karmakar, Ramya Arangaraju, Ragavi Alagarsamy

Background and aim: Metabolic health is closely related to periodontal health. Obesity, metabolic syndrome and diabetes mellitus are bidirectionally associated with periodontitis. The triglycerides-to-high-density lipoprotein cholesterol ratio (Ty/HDLc ratio) has emerged as a novel biomarker that can predict the risk of several chronic metabolic diseases. We conducted this systematic review to consolidate the available evidence regarding the association between the Ty/HDLc ratio and periodontitis.

Methods: We systematically searched PubMed, SCOPUS, Embase, and Web of Science databases for studies that assessed the Ty/HDLc ratio and its association with periodontitis till May 2025. No date or language restrictions were applied. We included all observational studies in adults and adolescents and excluded interventional studies, case reports, and animal studies. Study quality was assessed using the Joanna Briggs Institute critical appraisal checklist.

Results: Systematic screening of the search results yielded 7 studies that met our eligibility criteria. Sample sizes varied from 69 to 13,584 individuals aged 17 to 53 years across diverse population groups from Brazil, Mexico, South Korea, and Taiwan. All included studies were rated as having a low risk of bias. Despite demographic differences, all studies found a consistent positive association between the Ty/HDLc ratio and periodontitis prevalence and/or severity.

Conclusion: The findings of this review suggest that the serum Ty/HDLc ratio is positively associated with periodontitis prevalence and could be a promising biomarker that is simple, practical, cost-effective, routinely measured, and easily calculable, and holds the potential to be an indirect risk marker for periodontitis. Future research should focus on establishing the temporal relationship and establishing a definitive, gender-specific cut-off for periodontal risk assessment.

背景与目的:代谢健康与牙周健康密切相关。肥胖、代谢综合征和糖尿病与牙周炎有双向关系。甘油三酯与高密度脂蛋白胆固醇比值(Ty/HDLc ratio)已成为一种新的生物标志物,可以预测多种慢性代谢性疾病的风险。我们进行了这一系统综述,以巩固有关Ty/HDLc比率与牙周炎之间关系的现有证据。方法:我们系统地检索PubMed, SCOPUS, Embase和Web of Science数据库,以评估Ty/HDLc比率及其与牙周炎的关系,直到2025年5月。没有日期或语言限制。我们纳入了所有成人和青少年的观察性研究,排除了干预性研究、病例报告和动物研究。研究质量采用乔安娜布里格斯研究所关键评估清单进行评估。结果:系统筛选的搜索结果产生了7个研究符合我们的资格标准。样本大小从69到13584人不等,年龄在17到53岁之间,来自巴西、墨西哥、韩国和台湾的不同人群。所有纳入的研究均被评为低偏倚风险。尽管存在人口统计学差异,但所有研究都发现,Ty/HDLc比率与牙周炎患病率和/或严重程度之间存在一致的正相关。结论:本综述的研究结果表明,血清Ty/HDLc比值与牙周炎患病率呈正相关,可能是一种有前景的生物标志物,它简单、实用、经济、常规测量、易于计算,并有可能成为牙周炎的间接风险标志物。未来的研究应侧重于建立时间关系,并为牙周风险评估建立一个明确的、特定性别的截止点。
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引用次数: 0
Artificial intelligence in the study of oral lichen planus characteristics: a review. 人工智能在口腔扁平苔藓特征研究中的应用综述。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-04 DOI: 10.1038/s41405-025-00388-8
Huishun Yang, Ge Li, Changbin Zhao

Oral Lichen Planus (OLP) is a common chronic inflammatory disorder with a complex etiology and potential for malignant transformation, posing substantial challenges for clinical diagnosis and management. Conventional diagnostic approaches often depend on clinical experience and subjective assessment, which limits their accuracy and efficiency. Recent advances in artificial intelligence (AI) have introduced novel paradigms for investigating OLP characteristics. This review examines current applications, progress, challenges, and future directions of AI in OLP diagnosis and classification, prediction of disease progression and prognosis, and analysis of molecular features. Through a critical evaluation of existing research, AI demonstrates considerable potential to improve diagnostic objectivity, accelerate clinical decision-making, and reveal underlying disease mechanisms, thereby supporting the development of precision medicine for OLP.

口腔扁平苔藓(OLP)是一种常见的慢性炎症性疾病,病因复杂,具有恶性转化的潜力,对临床诊断和治疗提出了重大挑战。传统的诊断方法往往依赖于临床经验和主观评估,这限制了其准确性和效率。人工智能(AI)的最新进展为研究OLP特征引入了新的范式。本文综述了人工智能在OLP诊断和分类、疾病进展和预后预测、分子特征分析等方面的应用现状、进展、挑战和未来发展方向。通过对现有研究的批判性评估,人工智能在提高诊断客观性、加快临床决策和揭示潜在疾病机制方面显示出相当大的潜力,从而支持OLP精准医学的发展。
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引用次数: 0
Exploring the association between BMI and dental caries in 6-9-year-old children in Damascus, Syria: a cross-sectional study. 在叙利亚大马士革探索6-9岁儿童的体重指数与龋齿之间的关系:一项横断面研究
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1038/s41405-025-00383-z
Alaa Ashour, Lana Alshayeb, Mayssoon Dashash

Aim: To investigate the prevalence of dental caries and its association with Body Mass Index (BMI) among Syrian schoolchildren aged 6-9 years in Damascus.

Materials and methods: A cross-sectional study was conducted among 462 schoolchildren selected through multi-stage cluster sampling. Data were obtained using a structured questionnaire and clinical examinations based on WHO criteria. BMI was assessed according to standard protocols. Associations between dental caries and sociodemographic, dietary, oral hygiene factors, and BMI were analyzed using SPSS v25, with statistical significance set at P < 0.05.

Results: The prevalence of dental caries was 85.5%, with no significant differences by gender or age. Caries was significantly more frequent among children in public schools (87.7%; P = 0.042) and those from low socioeconomic backgrounds (95.7%; P < 0.001). Irregular fruit and vegetable intake and higher sugar consumption were associated with increased caries risk. BMI also showed a significant association with caries (P < 0.001), with overweight children exhibiting the highest prevalence (97.1%), although multivariable logistic regression confirmed BMI as an independent predictor with no difference between obese children and other classifications.

Conclusion: Dental caries is highly prevalent among Syrian children aged 6-9 years and shows significant associations with socioeconomic disadvantage, unhealthy dietary habits, poor oral hygiene, and increased BMI. Nevertheless, due to the cross-sectional design of the study, these associations do not establish a causal relationship between BMI and dental caries. Despite this limitation, the findings underscore the urgent need for integrated public health strategies to address both oral health and childhood obesity.

目的:调查大马士革6-9岁叙利亚学童龋齿患病率及其与身体质量指数(BMI)的关系。材料与方法:采用多阶段整群抽样的方法对462名小学生进行横断面研究。数据是根据世卫组织标准通过结构化问卷和临床检查获得的。根据标准方案评估BMI。采用SPSS v25软件分析龋病与社会人口学、饮食、口腔卫生因素及BMI的相关性,统计学意义为P。结果:龋病患病率为85.5%,性别、年龄差异无统计学意义。结论:叙利亚6 ~ 9岁儿童龋病高发,与社会经济条件差、不健康饮食习惯、口腔卫生差和体重指数增高有显著关系。然而,由于研究的横断面设计,这些关联并不能建立BMI和龋齿之间的因果关系。尽管存在这种局限性,但研究结果强调了迫切需要制定综合公共卫生战略来解决口腔健康和儿童肥胖问题。
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