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Recommended procedures for managing carious lesions in primary teeth with pulp involvement—a scoping review 处理涉及牙髓的原牙龋坏的推荐程序--范围审查
IF 3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-18 DOI: 10.1038/s41405-024-00259-8
Ilze Maldupa, Waraf Al-Yaseen, Julius Giese, Rokaia Ahmed Elagami, Daniela Prócida Raggio

Background

Managing dental caries in primary teeth with pulp involvement is a significant challenge. Clinical guidelines offer recommendations for effective management.

Aim

To identify and analyze policies, guidelines, and recommendations for treating primary teeth with pulp-involved carious lesions, highlighting existing research gaps and setting the foundation for future research.

Methods

A comprehensive search was conducted across databases (PubMed, Scopus, Embase, GIN, and LILACS) and grey literature sources (Trip and ProQuest) to identify guidelines, consensus, policy, and position statements on primary teeth pulp therapy and extraction thresholds. Two independent reviewers screened the abstracts and titles, followed by full-text screening.

Results

After removing duplication, of the 1098 records, 14 were selected for analysis. This review examined various treatments for deep caries lesions in primary teeth, including indirect/direct pulp capping, pulpotomy, pulpectomy, lesion sterilization/tissue restoration, and extraction. Time search was restricted to documents published from 30th January 2008 to 30th January 2024, offering insights into evolving clinical practices.

Conclusion

Treatment for carious lesions in primary teeth involving the pulp depends on clinical indications and may involve minimally invasive techniques. Recommended options are indirect pulp capping, pulpotomy, and pulpectomy, while direct capping and tooth removal are discouraged. Further research is needed to address gaps, improve guideline development, and enhance consistency of recommendations.

背景管理牙髓受累的乳牙龋齿是一项重大挑战。方法对数据库(PubMed、Scopus、Embase、GIN 和 LILACS)和灰色文献来源(Trip 和 ProQuest)进行了全面检索,以确定有关乳牙牙髓治疗和拔牙阈值的指南、共识、政策和立场声明。两位独立审稿人对摘要和标题进行了筛选,然后对全文进行了筛选。结果在去除重复的 1098 条记录后,选择了 14 条记录进行分析。该综述研究了针对乳牙深龋病变的各种治疗方法,包括间接/直接盖髓术、牙髓切断术、牙髓切除术、病变消毒/组织修复术和拔除术。时间搜索仅限于2008年1月30日至2024年1月30日期间发表的文献,从而为不断发展的临床实践提供了洞察力。结论对涉及牙髓的原牙龋坏的治疗取决于临床适应症,可能涉及微创技术。推荐的方法有间接盖髓术、牙髓切断术和牙髓切除术,而不鼓励直接盖髓和拔牙。需要进一步研究以弥补差距、改进指南的制定并提高建议的一致性。
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引用次数: 0
Comparison between AH plus sealer and total fill bioceramic sealer performance in previously untreated and retreatment cases of maxillary incisors with large-sized periapical lesion: a randomized controlled trial AH 加封闭剂与全填充生物陶瓷封闭剂在上颌切牙大面积根尖周病变的既往未治疗病例和再治疗病例中的性能比较:随机对照试验
IF 3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-12 DOI: 10.1038/s41405-024-00256-x
Eisa Wahbi, Hassan Achour, Yasser Alsayed Tolibah

Objective

This study aims to assess the efficacy of bioceramic (BC) sealer when applied using the single cone technique (SCT), in comparison to AH Plus sealer applied with the cold lateral condensation technique (LCT), concerning their impact on the healing of large-sized periapical lesions in both untreated and retreatment cases.

Materials and methods

A randomized controlled trial was conducted on 41 patients who had 60 permanent teeth in the maxillary incisors that were accompanied by large-sized periapical lesions. The included teeth were radiographed with cone beam computed tomography (CBCT) images and divided equally into two groups according to the endodontic treatment statute (30 untreated previous cases and 30 retreated cases). Subsequently, teeth received uniform preparation, irrigation, and dressing procedures. Then each group was divided equally according to the used sealer (15 teeth obturated using AH plus sealer with LCT and 15 teeth obturated using BC sealer with SCT). All cases were followed up after 6 and 12 months with CBCT images. Subsequently, the change in periapical lesion diameter (PLD) was observed as an indicator to determine the treatment outcome score. One-way ANOVA and Mann–Whitney U test were used to analyze the PLD changing and scoring the treatment outcome during the follow-up periods. The significance level was set at α = 0.05.

Results

There were no statistically significant differences between untreated and retreatment cases neither using AH plus sealer with LCT nor BC sealer with SCT regarding changes in PLD in the follow-up periods. Moreover, there were no significant differences between groups regarding treatment outcome scores in the follow-up periods. All groups showed a high success rate.

Conclusions

Successful treatment was achieved for untreated or retreatment maxillary incisor cases accompanied by large-sized periapical lesions using either BC sealer with the SCT or AH Plus sealer with LCT with a similar high success rate up to 12 months follow-up period.

本研究旨在评估生物陶瓷(BC)封闭剂在使用单锥技术(SCT)时与使用冷侧凝技术(LCT)的 AH Plus 封闭剂相比,对未经治疗和再治疗病例中大尺寸根尖周病变愈合的影响。这些患者的牙齿都经过了锥形束计算机断层扫描(CBCT)影像检查,并根据牙髓治疗章程平均分为两组(30 个以前未治疗过的病例和 30 个修复过的病例)。随后,牙齿接受统一的预备、冲洗和包扎程序。然后,根据封闭剂的使用情况将每组牙齿平均分成两组(15 颗牙齿使用 AH 加封闭剂和 LCT 封闭,15 颗牙齿使用 BC 封闭剂和 SCT 封闭)。所有病例均在 6 个月和 12 个月后接受 CBCT 图像随访。随后,观察根尖周病变直径(PLD)的变化,作为确定治疗效果评分的指标。采用单因素方差分析和曼-惠特尼 U 检验分析随访期间 PLD 的变化和治疗效果评分。结果未治疗病例和再治疗病例在随访期间的 PLD 变化方面,无论是使用 AH 加 LCT 封闭剂还是 BC 封闭剂加 SCT,均无显著统计学差异。此外,各组在随访期间的治疗效果评分方面也无明显差异。结论对于未经治疗或再治疗的上颌切牙病例,如果伴有大面积根尖周病变,无论是使用萃取封闭剂加SCT,还是使用AH加封闭剂加LCT,都能获得成功的治疗,而且在12个月的随访期内,成功率同样很高。
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引用次数: 0
Impact of LASER activated irrigation on the retrievability of Guttaflow bioseal (in-vitro study) 激光活化灌溉对 Guttaflow 生物胶片可回收性的影响(体外研究)
IF 3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-11 DOI: 10.1038/s41405-024-00254-z
Maram Obeid, Mohamed El Sayed Zaghloul, Tariq Yehia Abdelrahman

Background

This study aimed to evaluate the efficiency of diode LASER activated irrigation in the removal of GuttaFlow Bioseal root canal filling material during retreatment.

Materials and subjects

Root canals of forty-five single-rooted human mandibular premolar teeth were prepared with ProTaper Universal rotary system and obturated with lateral condensation obturation technique using Gutta Percha and Roeko GuttaFlow Bioseal root canal sealer. All specimens were retreated with ProTaper Universal Retreatment System files then divided to three different groups according to the technique of activation of irrigation. Samples were sectioned, and the residual filling remnants were captured using digital camera attached to microscope. Data was collected by three different interpreters, to eliminate the subjectivity of the process, using the ImageJ Software. The mean value of the data was obtained and evaluated statistically. The significance level was set at P ≤ 0.05.

Results

The remaining filling materials in the canals irrigated with ultrasonic activation (6.17 ± 1.42 at coronal level, 10.93 ± 1.91at middle level, and 14.58 ± 2.23 at apical level) were less than these irrigated with LASER activation (15.87 ± 3.78 at coronal level, 21.28 ± 4.44 at middle level, and 27.06 ± 2.68 at apical level). Maximum amount of remaining filling materials was present in the canals irrigated with passive side-vented syringe (23.07 ± 3.22 at coronal level, 38.09 ± 7.27 at middle level, and 34.24 ± 9.77 at apical level).

Conclusion

The activation of irrigation techniques used were incapable of complete removal of filling material at root canal walls.

材料和受试者用 ProTaper 通用旋转系统对 45 颗单根人类下颌前磨牙的根管进行预备,并用 Gutta Percha 和 Roeko GuttaFlow Bioseal 根管封闭剂采用侧向冷凝封闭技术进行封闭。使用 ProTaper 通用再治疗系统锉对所有样本进行再治疗,然后根据冲洗激活技术将样本分为三组。对样本进行切片,并使用连接到显微镜上的数码相机拍摄残余填充物。数据由三位不同的解释者使用 ImageJ 软件收集,以消除过程中的主观性。获得数据的平均值并进行统计评估。结果超声波激活灌洗的牙槽中剩余的填充材料(冠水平为 6.17 ± 1.42,中水平为 10.93 ± 1.91,根尖水平为 14.58 ± 2.23)少于激光激活灌洗的牙槽中(冠水平为 15.87 ± 3.78,中水平为 21.28 ± 4.44,根尖水平为 27.06 ± 2.68)。使用被动式侧排气注射器灌洗的根管中残留的充填材料最多(冠水平为 23.07 ± 3.22,中水平为 38.09 ± 7.27,根尖水平为 34.24 ± 9.77)。
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引用次数: 0
SWOT analysis of the dental hygiene profession in Pakistan-past, present, and future. 巴基斯坦牙科卫生专业的 SWOT 分析--过去、现在和未来。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-05 DOI: 10.1038/s41405-024-00255-y
Iqra Damani, Shazia Taimoor, Fahad Umer, Rashna Hoshang Sukhia, Ali Sadiq

Background: Pakistan faces a significant burden of oral diseases, which can be effectively reduced through preventive measures. Dentistry in Pakistan predominantly focuses on corrective dental procedures, increasing the treatment costs and widens disparities in oral healthcare access. To address this gap and meet the country's oral health needs, Aga Khan University initiated a Dental Hygiene program aimed to expand and diversify the oral health workforce and improving access to quality care in various healthcare settings. Due to limited awareness of this profession in the country, the program encounters significant challenges.

Aim: This article aims to present a SWOT analysis of the Dental Hygiene profession in Pakistan and propose evidence-based strategic changes to address these challenges and improve future outcomes.

Methods: A SWOT analysis was conducted to identify the internal strengths, weaknesses, external opportunities, and threats related to the Dental Hygiene profession, gathering both quantitative and qualitative data through a survey of relevant stakeholders (Consultants, Dental hygiene graduates, dental auxiliaries, fresh dental graduates, and prospective students) using Research Electronic Data Capture (REDCap).

Results: A total of 267 respondents participated in the survey, providing insights into the current state of the Dental Hygiene profession.

Conclusion: The analysis reveals that the Dental Hygiene profession in Pakistan requires robust advocacy, increased collaboration with dentists, opportunities for higher education, and the establishment of proper legislative frameworks to prevent professional transgression beyond the scope of practice.

背景:巴基斯坦面临着严重的口腔疾病负担,可通过预防措施有效减少这些疾病。巴基斯坦的牙科主要集中在矫正性牙科手术,增加了治疗成本,扩大了口腔医疗服务的差距。为了弥补这一差距,满足国家的口腔健康需求,阿迦汗大学启动了口腔卫生专业,旨在扩大口腔卫生人才队伍并使其多样化,改善在各种医疗机构获得优质护理的机会。目的:本文旨在对巴基斯坦的口腔卫生专业进行 SWOT 分析,并提出以证据为基础的战略变革,以应对这些挑战并改善未来的成果:通过使用研究电子数据采集(REDCap)对相关利益者(顾问、口腔卫生专业毕业生、牙科辅助人员、应届牙科毕业生和未来的学生)进行调查,收集定量和定性数据,进行 SWOT 分析,以确定与口腔卫生专业相关的内部优势、劣势、外部机会和威胁:共有 267 名受访者参与了调查,对口腔卫生专业的现状有了深入的了解:分析表明,巴基斯坦的牙科卫生专业需要大力宣传,加强与牙医的合作,提供高等教育机会,并建立适当的立法框架,以防止超越执业范围的专业越轨行为。
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引用次数: 0
Comparing efficacies of various papain-based enzyme agents and 2.4% sodium hypochlorite gel in chemomechanical caries removal: a randomized controlled trial. 比较各种木瓜蛋白酶酶制剂和 2.4% 次氯酸钠凝胶在化学机械除龋中的功效:随机对照试验。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-09-04 DOI: 10.1038/s41405-024-00258-9
M H D Baraa Alsayed, Mawia Karkoutly, Hassan Achour, Souad Abboud

Objective: This study aimed to evaluate and compare the efficacies of Papacarie Duo gel, Brix 3000, Selecti-Solve gel, 2.4% sodium hypochlorite gel, and conventional rotary-mechanical method in caries removal and to evaluate the patient comfort.

Methods: It was a single-blinded, randomized, parallel-group, active-controlled trial with five arms. It was conducted at the Department of Restorative Dentistry and Endodontics, Damascus University. Seventy-five specimens were randomly allocated into five groups: chemomechanical caries removal (CMCR) using Selecti-Solve gel (G1), BRIX3000 (G2), Papacarie DUO gel (G3), or 2.4% sodium hypochlorite gel (G4), and caries excavation using conventional rotary-mechanical method (G5) (control group). The trial considered healthy patients aged 18-40. Permanent molars with class I carious lesions extending to the middle third of dentin with no pulpal and/or periodontal pathology were included. The efficacy of caries removal was considered the primary outcome measure, and the secondary outcome measures were treatment time, volumetric measurement of the cavity, and pain assessment.

Results: The majority (73.30%) of cases from BRIX3000 and conventional rotary-mechanical method groups showed complete caries removal (p = 0.982). The mean time of caries removal was the highest (17.45 ± 4.42) in the 2.4% sodium hypochlorite gel group (p < 0.05), and the lowest (6.33 ± 1.69) was in the conventional rotary-mechanical method group (p < 0.05). The mean cavity volume was the highest (18.97 ± 9.76) in the Papacarie DUO gel group, and the lowest (14.87 ± 4.76) was in the 2.4% sodium hypochlorite gel group (p = 0.506). The conventional rotary-mechanical group exhibited the highest mean score (5.40 ± 1.72) of pain (p < 0.05). However, the mean score (2.67 ± 1.11) of pain reported reduced in the BRIX3000 group.

Conclusions: CMCR agents could be a potential substitute for conventional rotary instrumentation methods, taking into account the long working time.

研究目的本研究旨在评估和比较Papacarie Duo凝胶、Brix 3000、Selecti-Solve凝胶、2.4%次氯酸钠凝胶和传统旋转机械法在去除龋齿方面的疗效,并评估患者的舒适度:这是一项单盲、随机、平行组、主动对照试验,共有五组。试验在大马士革大学牙体修复和牙髓病学系进行。75例标本被随机分配到五组:使用Selecti-Solve凝胶(G1)、BRIX3000(G2)、Papacarie DUO凝胶(G3)或2.4%次氯酸钠凝胶(G4)的化学机械除龋(CMCR)组,以及使用传统旋转机械方法的龋齿挖掘组(G5)(对照组)。试验对象为 18-40 岁的健康患者。试验对象包括Ⅰ类龋坏扩展至牙本质中三分之一处且无牙髓和/或牙周病变的恒磨牙患者。龋齿去除的疗效被认为是主要结果指标,次要结果指标是治疗时间、龋洞体积测量和疼痛评估:结果:BRIX3000 和传统旋转机械法组的大多数病例(73.30%)显示龋齿完全清除(P = 0.982)。2.4% 次氯酸钠凝胶组的平均除龋时间最长(17.45 ± 4.42)(p 结论:BRIX3000 和传统旋转机械法组的平均除龋时间最长(17.45 ± 4.42):考虑到工作时间较长,CMCR 药剂有可能替代传统的旋转器械方法。
{"title":"Comparing efficacies of various papain-based enzyme agents and 2.4% sodium hypochlorite gel in chemomechanical caries removal: a randomized controlled trial.","authors":"M H D Baraa Alsayed, Mawia Karkoutly, Hassan Achour, Souad Abboud","doi":"10.1038/s41405-024-00258-9","DOIUrl":"10.1038/s41405-024-00258-9","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate and compare the efficacies of Papacarie Duo gel, Brix 3000, Selecti-Solve gel, 2.4% sodium hypochlorite gel, and conventional rotary-mechanical method in caries removal and to evaluate the patient comfort.</p><p><strong>Methods: </strong>It was a single-blinded, randomized, parallel-group, active-controlled trial with five arms. It was conducted at the Department of Restorative Dentistry and Endodontics, Damascus University. Seventy-five specimens were randomly allocated into five groups: chemomechanical caries removal (CMCR) using Selecti-Solve gel (G1), BRIX3000 (G2), Papacarie DUO gel (G3), or 2.4% sodium hypochlorite gel (G4), and caries excavation using conventional rotary-mechanical method (G5) (control group). The trial considered healthy patients aged 18-40. Permanent molars with class I carious lesions extending to the middle third of dentin with no pulpal and/or periodontal pathology were included. The efficacy of caries removal was considered the primary outcome measure, and the secondary outcome measures were treatment time, volumetric measurement of the cavity, and pain assessment.</p><p><strong>Results: </strong>The majority (73.30%) of cases from BRIX3000 and conventional rotary-mechanical method groups showed complete caries removal (p = 0.982). The mean time of caries removal was the highest (17.45 ± 4.42) in the 2.4% sodium hypochlorite gel group (p < 0.05), and the lowest (6.33 ± 1.69) was in the conventional rotary-mechanical method group (p < 0.05). The mean cavity volume was the highest (18.97 ± 9.76) in the Papacarie DUO gel group, and the lowest (14.87 ± 4.76) was in the 2.4% sodium hypochlorite gel group (p = 0.506). The conventional rotary-mechanical group exhibited the highest mean score (5.40 ± 1.72) of pain (p < 0.05). However, the mean score (2.67 ± 1.11) of pain reported reduced in the BRIX3000 group.</p><p><strong>Conclusions: </strong>CMCR agents could be a potential substitute for conventional rotary instrumentation methods, taking into account the long working time.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11375084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interfacial assessment of cention forte vs. equia forte and two forms of calcium silicate cements at two time intervals. 在两个时间间隔内对 cention forte 与 equia forte 以及两种形式的硅酸钙水泥进行界面评估。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-24 DOI: 10.1038/s41405-024-00252-1
Heba Abdelkafy, Nada A Salem, Rasha Mohamed Marzouk, Alaa M Eldehna

Aim: Assessment of interfacial gaps and mechanical impact of the materials layering between Cention Forte and Equia Forte restorations with two forms of Calcium Silicate Cements (CSCs) at the interfacial surface at two-time intervals.

Methodology: Six groups of 72 primary molars were categorized by restorative material type and CSCs: Cention Forte(C), Cention Forte without primer (Cx), and Equia Forte (EQ). All were applied over MTA Angelus powder (M) or Bio-C Repair putty (P). Restorative materials were applied immediately (subgroup A) or delayed (Subgroup B). SEM was used to detect interface gaps. EDX measured element migration from the interface at specific distances. Vickers Microhardness Tester assessed microhardness.

Results: Regarding SEM, there were no gaps between CSCs interfaces of both types (Powder and Putty) with all restorations at two-time intervals. Microhardness, there was a statistically nonsignificant difference between subgroups A & B in all groups except at 200 µm in the Cention groups (subgroup A) was significantly lower than (subgroup B) (P = 0.002, 0.03) respectively. At 400 µm in the MTA Angelus powder Group Cx, subgroup A was significantly higher than subgroup B (P = 0.003*). While Bio-C Repair putty in Group EQ (subgroup A) was significantly higher than (Subgroup B) (P < 0.0001*).

Conclusions: The delayed application of Cention Forte over two types of CSCs is useful in getting the maximum HV and, in turn, the long survival rate of the filling. Immediate application of Cention Forte without primer is better over both types of CSCs. The delayed application of Equia Forte over MTA angelus powder is more considerable.

目的:评估Cention Forte和Equia Forte修复体之间的界面间隙和材料分层的机械影响,在界面表面使用两种形式的硅酸钙水门汀(CSC),每隔两次:按修复材料类型和 CSCs 对六组 72 颗初级磨牙进行分类:Cention Forte (C)、Cention Forte(无底漆)(Cx) 和 Equia Forte (EQ)。所有材料都覆盖在 MTA Angelus 粉末 (M) 或 Bio-C 修复腻子 (P) 上。修复材料立即使用(A 组)或延迟使用(B 组)。SEM 用于检测界面间隙。EDX 测量元素从特定距离的界面迁移的情况。维氏硬度计对显微硬度进行评估:扫描电子显微镜(SEM)显示,所有修复体的两种类型(粉末和油灰)界面之间都没有间隙。显微硬度方面,除了在 200 微米处 Cention 组(A 组)明显低于 B 组(P = 0.002,0.03)外,A 组和 B 组在所有组别中均无显著差异。在 MTA Angelus 粉末 Cx 组中,400 微米处 A 亚组明显高于 B 亚组(P = 0.003*)。而 EQ 组(A 子组)的 Bio-C 修复腻子明显高于(B 子组)(P 结论):在两种类型的 CSC 上延迟使用 Cention Forte 有助于获得最大 HV 值,进而延长填充物的存活率。在两种类型的 CSC 上立即使用 Cention Forte 而不使用底漆的效果更好。在 MTA 安琪拉粉上延迟使用 Equia Forte 的效果更为显著。
{"title":"Interfacial assessment of cention forte vs. equia forte and two forms of calcium silicate cements at two time intervals.","authors":"Heba Abdelkafy, Nada A Salem, Rasha Mohamed Marzouk, Alaa M Eldehna","doi":"10.1038/s41405-024-00252-1","DOIUrl":"10.1038/s41405-024-00252-1","url":null,"abstract":"<p><strong>Aim: </strong>Assessment of interfacial gaps and mechanical impact of the materials layering between Cention Forte and Equia Forte restorations with two forms of Calcium Silicate Cements (CSCs) at the interfacial surface at two-time intervals.</p><p><strong>Methodology: </strong>Six groups of 72 primary molars were categorized by restorative material type and CSCs: Cention Forte(C), Cention Forte without primer (Cx), and Equia Forte (EQ). All were applied over MTA Angelus powder (M) or Bio-C Repair putty (P). Restorative materials were applied immediately (subgroup A) or delayed (Subgroup B). SEM was used to detect interface gaps. EDX measured element migration from the interface at specific distances. Vickers Microhardness Tester assessed microhardness.</p><p><strong>Results: </strong>Regarding SEM, there were no gaps between CSCs interfaces of both types (Powder and Putty) with all restorations at two-time intervals. Microhardness, there was a statistically nonsignificant difference between subgroups A & B in all groups except at 200 µm in the Cention groups (subgroup A) was significantly lower than (subgroup B) (P = 0.002, 0.03) respectively. At 400 µm in the MTA Angelus powder Group Cx, subgroup A was significantly higher than subgroup B (P = 0.003*). While Bio-C Repair putty in Group EQ (subgroup A) was significantly higher than (Subgroup B) (P < 0.0001*).</p><p><strong>Conclusions: </strong>The delayed application of Cention Forte over two types of CSCs is useful in getting the maximum HV and, in turn, the long survival rate of the filling. Immediate application of Cention Forte without primer is better over both types of CSCs. The delayed application of Equia Forte over MTA angelus powder is more considerable.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11344803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does strontium coated titanium implants enhance the osseointegration in animal models under osteoporotic condition? A systematic review and meta-analysis. 锶涂层钛植入物能否增强骨质疏松动物模型的骨结合?系统综述与荟萃分析。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-24 DOI: 10.1038/s41405-024-00220-9
Osama Sayed, Mohamed Mahmoud Abdalla, Ayman Elsayed, Yehia El-Mahallawy, Haytham Al-Mahalawy

Purpose: The aim of this study was to systematically review the literature to address the effect of strontium modified titanium implants on the osseointegration in the presence of osteoporotic conditions through animal models.

Materials and methods: The databases (PubMed, Scopus, Web of Science, and EBSCO) were searched electronically, and manual searches were performed till December 2022 to identify preclinical studies on the osseointegration of strontium coated titanium implants in animals with induced osteoporotic conditions. The primary outcomes were the bone-implant contact percentage (BIC%), bone area (BA) from the histomorphometric analysis, and the osseointegration parameters from biomechanical tests; the secondary outcomes were the osseointegration parameters from the micro computed tomography.

Results: Nineteen articles were included for the quantitative analysis on basis of the inclusion criteria. The results revealed that Sr-modified implants showed a significant 19.05% increase in BIC, and 15.01% increase in BA. The results of biomechanical tests indicated a significant effect in favor of Sr-coated implants. Furthermore, Results of the secondary outcomes supported the significant advantages of Sr-coated implants over the un-coated implants. The overall, systematic analysis of implants osteointegration parameters proved a significant increase in favor of Sr-coated titanium implants (P < 0.01).

Conclusion: The present results provide evidence that strontium-coated titanium implants enhanced the osseointegration in animal models under osteoporotic condition as this surface modification techniques have improved the mechanical and biological properties of the titanium implants.

目的:本研究旨在通过动物模型系统地回顾文献,探讨锶修饰的钛植入物在骨质疏松情况下对骨结合的影响:对数据库(PubMed、Scopus、Web of Science 和 EBSCO)进行了电子检索,并在 2022 年 12 月之前进行了人工检索,以确定关于锶涂层钛植入物在诱导骨质疏松情况下的骨结合的临床前研究。主要研究结果为组织形态学分析得出的骨-植入体接触百分比(BIC%)、骨面积(BA)以及生物力学测试得出的骨结合参数;次要研究结果为显微计算机断层扫描得出的骨结合参数:根据纳入标准,19 篇文章被纳入定量分析。结果显示,锶改性种植体的BIC显著增加了19.05%,BA增加了15.01%。生物力学测试结果表明,锶涂层种植体的效果显著。此外,次要结果表明,与未涂层的种植体相比,有 Sr 涂层的种植体具有明显优势。对植入物骨整合参数的整体系统分析证明,Sr 涂层钛植入物的骨整合参数明显增加(P 结论:Sr 涂层钛植入物的骨整合参数明显增加:本研究结果证明,锶涂层钛植入物增强了骨质疏松动物模型的骨结合,因为这种表面改性技术改善了钛植入物的机械和生物特性。
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引用次数: 0
Effects of online marketplace-sourced over-the-counter tooth whitening products on the colour, microhardness, and surface topography of enamel: an in vitro study. 网络市场上的非处方牙齿美白产品对珐琅质颜色、微硬度和表面形貌的影响:一项体外研究。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-23 DOI: 10.1038/s41405-024-00253-0
Radhika Agarwal, Nikki Vasani, Urmila Sachin Mense, Niharika Prasad, Aditya Shetty, Srikant Natarajan, Arindam Dutta, Manuel S Thomas

Objectives: This study compared the whitening effect, microhardness, and enamel surface alterations of over-the-counter (OTC) tooth bleaching products with those of a dentist-prescribed at-home bleaching agent.

Materials and methods: The products available on a popular online marketplace were comprehensively searched and then rated using a specific formula. The effects of the lowest-rated OTC agent (LRA) and the highest-rated OTC agent (HRA) were compared with those of a dentist-prescribed bleaching agent (DPA) on the enamel of extracted human teeth. The bleaching efficacy, post-bleaching microhardness changes, and morphological alterations were assessed by spectrophotometric analysis, Vickers hardness testing, and scanning electron microscopy (SEM) respectively. Statistical analyses included one-way ANOVA and post hoc tests, maintaining a significance level of P < 0.05.

Results: The search of the online marketplace revealed 15 products. The LRA (Teeth Whitening Serum Gel, GEN, China) and the HRA (Bright White-Lovely Smile Premium Teeth Whitening strips, Ray of Smile, USA) were identified on the basis of their ranking. DPA resulted in significantly better tooth whitening than did LRA. The enamel microhardness was lower in the LRA treatment group (14.2%) than in the control and HRA treatment groups (8.84% and 7.26%, respectively). LRA also caused severe topographical alterations to the enamel.

Conclusion: Compared with the poorly rated product, the dentist-prescribed tooth bleaching product resulted in greater colour improvement, less microhardness reduction, and surface changes. The highest-rated product was comparable with the dentist-prescribed agent in this study.

研究目的:本研究比较了非处方(OTC)牙齿漂白产品与牙医处方的居家漂白剂的美白效果、微硬度和珐琅质表面变化:对一家热门在线市场上的产品进行了全面搜索,然后使用特定公式对其进行评级。比较了评级最低的 OTC 药剂(LRA)和评级最高的 OTC 药剂(HRA)与牙医处方漂白剂(DPA)对拔出的人类牙齿珐琅质的效果。通过分光光度分析、维氏硬度测试和扫描电子显微镜(SEM)分别评估了漂白效果、漂白后的微硬度变化和形态改变。统计分析包括单因素方差分析和事后检验,显著性水平保持在 P 结果:在网上市场搜索到 15 种产品。根据排名确定了 LRA(牙齿美白精华凝胶,中国 GEN 公司)和 HRA(亮白-可爱微笑高级牙齿美白条,美国 Ray of Smile 公司)。DPA 的牙齿美白效果明显优于 LRA。LRA 治疗组的珐琅质微硬度(14.2%)低于对照组和 HRA 治疗组(分别为 8.84% 和 7.26%)。LRA 还导致釉质发生严重的地形改变:结论:与评级较低的产品相比,牙医处方的牙齿漂白产品能带来更大的颜色改善、更少的微硬度降低和表面变化。在这项研究中,评级最高的产品与牙医处方的药剂不相上下。
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引用次数: 0
Flowable composite as an alternative to adhesive resin cement in bonding hybrid CAD/CAM materials: in-vitro study of micro-shear bond strength. 在粘接 CAD/CAM 混合材料时,可流动复合材料可替代粘接树脂水泥:微剪切粘接强度的体外研究。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-20 DOI: 10.1038/s41405-024-00251-2
Eman Ezzat Youssef Hassanien, Zeinab Omar Tolba

Objective: To assess the micro-shear bond strength of light-cured adhesive resin cement compared to flowable composite to hybrid CAD/CAM ceramics.

Materials and methods: Rectangular discs were obtained from polymer-infiltrated (Vita Enamic; VE) and nano-hybrid resin-matrix (Voco Grandio; GR) ceramic blocks and randomly divided according to the luting agent; light-cured resin cement (Calibra Veneer; C) and flowable composite (Neo Spectra ST flow; F), resulting in four subgroups; VE-C, VE-F, GR-C and GR-F. Substrates received micro-cylinders of the tested luting agents (n = 16). After water storage, specimens were tested for micro-shear bond strength (µSBS) using a universal testing machine at 0.5 mm/min cross-head speed until failure and failure modes were determined. After testing for normality, quantitative data were expressed as mean and standard deviation, whereas, qualitative data were expressed as percentages. Quantitative data were statistically analysed using Student t test at a level of significance (P ≤ 0.05).

Results: Group GR-F showed the highest µSBS, followed by VE-C, VE-F and GR-C respectively, although statistically insignificant. All groups showed mixed and adhesive failure modes, where VE-F and GR-C showed the highest mixed failures followed by GR-C and VE-C respectively.

Conclusions: After short-term aging, flowable composite and light-cured resin cement showed high comparable bond strength when cementing VE and GR.

目的评估光固化粘接树脂水泥与流动复合材料对混合 CAD/CAM 陶瓷的微剪切粘接强度:从聚合物浸润(Vita Enamic;VE)和纳米混合树脂基质(Voco Grandio;GR)陶瓷块中获得矩形盘,并根据粘结剂(光固化树脂粘结剂(Calibra Veneer;C)和可流动复合材料(Neo Spectra ST flow;F))随机分为四组:VE-C、VE-F、GR-C 和 GR-F。基底接受了测试的胶合剂微圆柱体(n = 16)。贮水后,使用万能试验机以 0.5 毫米/分钟的十字头速度对试样进行微剪切粘接强度(µSBS)测试,直至确定失效和失效模式。经过正态性测试后,定量数据以平均值和标准偏差表示,而定性数据则以百分比表示。定量数据采用学生 t 检验进行统计分析,显著性水平为 P ≤ 0.05:结果:GR-F 组的 µSBS 值最高,其次分别是 VE-C、VE-F 和 GR-C,但统计意义不大。所有组都显示出混合和粘合失效模式,其中 VE-F 和 GR-C 显示出最高的混合失效,其次分别是 GR-C 和 VE-C:结论:短期老化后,可流动复合材料和光固化树脂粘接剂在粘接 VE 和 GR 时显示出很高的可比粘接强度。
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引用次数: 0
Treatment decisions of patients with Class II Division 2 malocclusion and severe tooth wear: a systematic review. II 类 2 分区错牙合畸形和严重牙齿磨损患者的治疗决策:系统综述。
IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-13 DOI: 10.1038/s41405-024-00248-x
Yuhan Ma, Weijia Zhao, Sisi Zhang, Xiaoting Jin, Jianhao Xu, Baiping Fu, Ying Shi

Background: The treatment strategy for patients with severe tooth wear associated with Class II Division 2 malocclusion remains a major challenge for dental practitioners.

Objectives: To systematically review and summarize the literature on treatment strategies, restoration procedures and clinical outcomes for Class II Division 2 malocclusion patients with severe tooth wear.

Methods: A literature review was conducted using Pubmed, Embase, the Cochrane Library, and Web of Science to identify eligible articles. Publications until October 16th, 2023 were searched independently and cross-checked by two researchers.

Results: Of 1513 articles screened, 10 reports detailed treatment processes, including six males and four females aged 34-68 years old. Four articles recorded pre-treatment freeway space (FWS) values ranging from 5 to 9 mm. All ten cases had significant occlusal vertical dimension (OVD) loss and the increase in OVD after treatment ranged from 1 to 7 mm. Pre-prosthetic orthodontic treatment was performed in two cases, in one of which only the maxillary region was orthodontically treated. The most common restorations provided were full coverage restorations. In most cases, temporary restorations were applied before the permanent restorations for eight weeks to six months. Four different sequences of final restoration were proposed. Follow-up ranged from four months to six years and included seven patients, one of them showed symptoms of temporomandibular disorder (TMD).

Conclusions: A multidisciplinary team (MDT) approach to treatment is recommended. Consideration of pre-prosthetic orthodontic treatment is essential. Commonly used cephalometric measurements for anterior teeth include the interincisal angle and collum angle. The increases in OVD ranging from 1 to 7 mm can be effectively accommodated. Temporary restorations are recommended to accommodate the OVD, and the transition periods of 8 weeks to 6 months help the patients adapted well. Four different sequences for final rehabilitation have demonstrated positive clinical outcomes. Full crown restorations have emerged as the preferred choice for the ultimate restoration of these patients.

背景:对于牙齿严重磨损的II类2型错合畸形患者,治疗策略仍然是牙科医生面临的一大挑战:系统回顾和总结有关严重牙齿磨损的 II 类 2 分区错颌畸形患者的治疗策略、修复程序和临床结果的文献:方法:使用 Pubmed、Embase、Cochrane Library 和 Web of Science 进行文献综述,以确定符合条件的文章。结果:在筛选出的 1513 篇文章中,有 10 篇关于严重牙齿磨损的报道:在筛选出的 1513 篇文章中,有 10 篇报告详细介绍了治疗过程,其中包括 6 名男性和 4 名女性,年龄在 34-68 岁之间。四篇文章记录了治疗前的自由空间(FWS)值,范围在 5 至 9 毫米之间。所有十个病例都有明显的咬合垂直度(OVD)损失,治疗后咬合垂直度增加了 1 到 7 毫米不等。有两个病例进行了修复前正畸治疗,其中一个病例只对上颌区域进行了正畸治疗。最常见的修复方式是全覆盖修复。在大多数病例中,在永久修复前会先进行八周到六个月的临时修复。提出了四种不同的最终修复顺序。随访时间从四个月到六年不等,包括七名患者,其中一人出现了颞下颌关节紊乱(TMD)症状:结论:建议采用多学科团队(MDT)方法进行治疗。结论:建议采用多学科团队(MDT)方法进行治疗,必须考虑修复前的正畸治疗。前牙常用的头颅测量包括龈间角和牙龈角。可以有效地适应 OVD 1 到 7 毫米的增加。建议使用临时修复体来适应 OVD,8 周到 6 个月的过渡期可以帮助患者很好地适应。四种不同的最终修复顺序都取得了积极的临床效果。全冠修复已成为这些患者最终修复的首选。
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引用次数: 0
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