Journal of Healthcare Quality Research最新文献

英文中文

Design and application of a survey for measuring multidimensional access to health services 设计和应用一项调查，以衡量获得保健服务的多角度情况。

IF 1 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Healthcare Quality Research

Pub Date : 2025-09-01 DOI: 10.1016/j.jhqr.2025.101154

G.P. González , M. Geri , M.S. Moreno , M.F. Arnaudo , F.P. Lago , M.E. Elorza , N.S. Moscoso , A.M. Blanco

Objectives

Access to health services is a critical factor in ensuring equitable healthcare delivery. Understanding patient perspectives on barriers and obstacles to healthcare access is essential for improving health outcomes. This study aims to design and test an instrument to assess self-perceived access to health services across different levels of care, encompassing all process dimensions.

Methods

The survey, constructed with an interdisciplinary approach, is administered at the household level. It was validated by experts and approved by a Bioethics Committee. This survey was conducted in a medium-sized city in Argentina.

Results

The validated instrument provides a comprehensive tool to investigate, from the patient's perspective and preferences, the barriers that prevent a health need from becoming a demand and the obstacles to effectively using the needed healthcare service. The implementation of the survey revealed significant insights into these issues.

Conclusions

Our instrument offers valuable insights into the patient-perceived barriers to healthcare access. It is a robust tool for identifying the obstacles that impede the utilization of health goods and services in the different levels of care, thereby improving healthcare delivery systems.

目标：获得保健服务是确保公平提供保健服务的关键因素。了解患者对获得医疗保健的障碍和障碍的看法对于改善健康结果至关重要。本研究旨在设计和测试一种工具，以评估不同护理水平的自我感知获得卫生服务的机会，包括所有过程维度。方法：本调查采用跨学科方法，在家庭层面进行。它经过了专家的验证，并得到了生物伦理委员会的批准。这项调查是在阿根廷的一个中等城市进行的。结果：经过验证的仪器提供了一个全面的工具，从患者的角度和偏好来调查阻止健康需求成为需求的障碍，以及有效使用所需医疗保健服务的障碍。调查的实施揭示了对这些问题的重要见解。结论：我们的仪器提供了宝贵的见解，患者感知的障碍，以获得医疗保健。它是一种强有力的工具，可用于确定阻碍在不同级别的保健中使用卫生物品和服务的障碍，从而改进卫生保健提供系统。

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引用次数: 0

¿Son los nanorrobots una alternativa de mejora en la calidad del tratamiento de la insuficiencia respiratoria? 纳米机器人是提高呼吸衰竭治疗质量的替代方法吗？

IF 1 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Healthcare Quality Research

Pub Date : 2025-08-18 DOI: 10.1016/j.jhqr.2025.101157

Alejandro González-Castro , Camilo González Fernández , Arturo Ávila

引用次数: 0

Float nurses and patient safety: A checklist to prevent ‘second victims’ 浮动护士和患者安全：防止“第二受害者”的清单

IF 1 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Healthcare Quality Research

Pub Date : 2025-08-18 DOI: 10.1016/j.jhqr.2025.101159

M. Bennasar-Veny , E. Castro-Sánchez

引用次数: 0

[Home-based occupational therapy and primary care nursing program]. [以家庭为基础的职业治疗和初级保健护理计划]。

IF 1 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Healthcare Quality Research

Pub Date : 2025-08-16 DOI: 10.1016/j.jhqr.2025.101155

N Plaza-Briones, M Carrete-Gómez, L Secanell-Capdevila, J A López-Segura, J Grau-Sánchez, L Vidaña-Moya

Introduction and objective: To determine the impact of a home-based occupational therapy and nursing program, on autonomy in activities of daily living, quality of life, and falls in people with chronic diseases and complex needs.

Material and methods: A pre-post quasi-experimental quantitative study with a consecutive sample based on the usual clinical practice of home care teams. The Barthel Index, Lawton & Brody Scale, Short Falls Efficacy Scale, Life Space Assessment, Quality of Life Index, and falls in the last two months were assessed. A paired sample pre-post hypothesis contrast analysis was performed, stratified by sex and care profile.

Results: A total of 115 participants were recruited, of whom 8 were dropouts. The program showed statistically significant improvement in all indicators. Notably, the Barthel Index increased by 10,0 (IC 95%: 8.2; 11.8) (p≤0.001), reducing the level of dependency from severe to moderate. The Lawton & Brody scale increased by 0.6 (IC 95%: 0.4; 0.8) globally, and the percentage of participants with at least one fall in the past two months decreased from 40.4% to 2.0%.

Conclusions: The intervention performed by the occupational therapist is key in the promotion of autonomy, falls prevention and quality of life. It is a value to be taken into account in the configuration of home care teams in primary care.

前言和目的：确定以家庭为基础的职业治疗和护理方案对慢性疾病和复杂需求患者日常生活活动的自主性、生活质量和跌倒的影响。材料与方法：基于家庭护理团队的常规临床实践，采用连续样本进行前后准实验定量研究。采用Barthel指数、Lawton & Brody量表、Short Falls疗效量表、生活空间评估、生活质量指数和最近两个月的跌倒进行评估。对配对样本进行假设前后对比分析，按性别和护理概况分层。结果：共招募了115名参与者，其中8名是中途退学者。该方案在所有指标上都显示出统计学上的显著改善。值得注意的是，Barthel指数增加了10,0 (IC 95%: 8.2; 11.8) (p≤0.001)，依赖性水平从严重降低到中度。Lawton & Brody量表在全球范围内上升了0.6 (IC 95%: 0.4; 0.8)，在过去两个月内至少跌倒过一次的参与者比例从40.4%下降到2.0%。结论：职业治疗师的干预是促进自主性、预防跌倒和提高生活质量的关键。在初级保健家庭护理小组的配置中应考虑到这一价值。

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引用次数: 0

Effectiveness of an organizational intervention aimed to reduce burnout and emotional distress, and improve quality of life of an Obstetrics-Gynecology team. 旨在减少倦怠和情绪困扰，提高妇产科团队生活质量的组织干预的有效性。

IF 1 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Healthcare Quality Research

Pub Date : 2025-08-16 DOI: 10.1016/j.jhqr.2025.101156

J J Dapueto, F Nozar, S Artucio, D Sánchez, P Aguirrezábal, L Briozzo

Background: Burnout and promoting physician well-being have become priorities for healthcare institutions. Obstetrics and Gynecology teams are susceptible to stress due to work demands and limited resources. Organizational interventions are increasingly recognized as crucial to mitigating burnout and improving professional well-being.

Aims: To assess the impact of an organizational-level intervention designed to reduce burnout and emotional distress, and improve well-being and quality of life among faculty members and residents of an Obstetrics/Gynecology team.

Methods: A structured organizational intervention was implemented in the Obstetrics/Gynecology Academic Unit A, Universidad de la República, in Uruguay. The effectiveness was assessed using validated psychometric instruments, Maslach Burnout Inventory - Human Services Survey, Oldenburg Burnout Inventory, PROMIS Global Health Scale, World Health Organization Anxiety and Depression Scale (WHO-5). Statistical analyses included Wilcoxon signed-rank tests and effect size calculations.

Results: Of the 76 invited participants, 61 completed baseline assessments, and 30 completed follow-up assessments. Significant improvements were observed in burnout, emotional well-being with effect sizes ranged from large to very large (0.50-0.74). The prevalence of burnout decreased from 63.3% to 40.0% (p=0.039), and high-risk emotional distress (WHO-5 <50 points) decreased from 53.3% to 26.7% (p=0.039).

Conclusions: A structured organizational-level intervention effectively reduced burnout and improved well-being among faculty and obstetrics and gynecology residents. These findings are consistent with previous research indicating that organizational interventions produce considerable benefits at work. Further studies with larger samples are needed to confirm long-term efficacy and generalizability to other health care settings.

背景：职业倦怠和促进医生的福祉已成为医疗机构的优先事项。由于工作需求和资源有限，妇产科团队容易受到压力的影响。人们越来越认识到，组织干预对于减轻职业倦怠和提高职业幸福感至关重要。目的：评估组织层面干预的影响，旨在减少倦怠和情绪困扰，提高妇产科团队教职员工和住院医生的幸福感和生活质量。方法：在乌拉圭República大学妇产科学术A单元实施结构化组织干预。使用经过验证的心理测量工具、Maslach职业倦怠量表-人类服务调查、Oldenburg职业倦怠量表、PROMIS全球健康量表、世界卫生组织焦虑和抑郁量表（WHO-5）来评估有效性。统计分析包括Wilcoxon sign -rank检验和效应量计算。结果：在76名受邀参与者中，61人完成了基线评估，30人完成了随访评估。在倦怠、情绪幸福感方面观察到显著的改善，效应量从大到非常大（0.50-0.74）。倦怠的患病率从63.3%下降到40.0% (p=0.039)，高危情绪困扰（WHO-5）。结论：结构化的组织层面干预有效地减少了教师和妇产科住院医师的倦怠，提高了幸福感。这些发现与先前的研究一致，表明组织干预在工作中产生相当大的好处。需要更大样本的进一步研究来确认长期疗效和推广到其他卫生保健机构。

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引用次数: 0

Ethical challenges of AI-based innovation in the Spanish National Health System 西班牙国家卫生系统中基于人工智能创新的伦理挑战。

IF 1.1 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Healthcare Quality Research

Pub Date : 2025-07-01 DOI: 10.1016/j.jhqr.2025.02.004

I. de Lecuona

引用次数: 0

Understanding quality and efficiency of cancer care services from oncologist's perspective 从肿瘤学家的角度理解癌症护理服务的质量和效率

IF 1.1 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Healthcare Quality Research

Pub Date : 2025-06-17 DOI: 10.1016/j.jhqr.2025.101150

S. Cinaroglu , B. Saylan , S. Zararsız

Objectives

Enhancing the quality of critical care services requires a comprehending of the elements that contribute to their efficiency. This study proposes a new way of understanding of cancer service quality and efficiency from oncology professionals’ perspective by combining crisp and stochastic DEA techniques blended with a fully ranking DEA–AHP approach.

Methods

Our analysis is based on the analysis of cancer care services efficiency of 81 provinces of Turkey by using indicators of cancer care process, quality of cancer care, general quality of health and cancer care services, development level of provinces, and cancer mortality. Based on the DEA–AHP integrated model with fuzzy AHP weights, provinces located in poor areas are the least efficient in terms of cancer care services. Harmonized crisp and stochastic province-level efficiency analysis serves as a mediator variable to better understand the efficiency of cancer services by using geospatial data in oncology and allows capturing the efficiency dynamics of cancer care.

Results

The study findings highlight that the least efficient provinces for cancer care services are those that are mainly found in underdeveloped areas.

Conclusion

Cancer policy makers and oncology professionals should consider the efficiency dynamics of cancer care which acts as a mediator variable to help better understand the efficiency of cancer services through the use of spatial differences in oncology.

目的提高重症监护服务的质量，需要了解有助于提高其效率的要素。本研究将清晰随机的DEA技术与全排序DEA - ahp方法相结合，从肿瘤学专业人员的角度出发，提出了一种理解癌症服务质量和效率的新方法。方法采用癌症护理流程、癌症护理质量、卫生与癌症护理服务总体质量、各省发展水平、癌症死亡率等指标，对土耳其81个省的癌症护理服务效率进行分析。基于模糊层次分析法权重的DEA-AHP综合模型，贫困地区省份的癌症护理服务效率最低。统一的清晰和随机的省级效率分析作为中介变量，通过使用肿瘤学中的地理空间数据更好地了解癌症服务的效率，并允许捕获癌症护理的效率动态。结果研究发现，癌症护理服务效率最低的省份主要分布在欠发达地区。结论肿瘤政策制定者和肿瘤专业人员应考虑肿瘤护理效率动态作为中介变量，利用肿瘤空间差异更好地理解肿瘤服务效率。

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引用次数: 0

Results of a survey to evaluate awareness and practices of critical incident reported by anaesthesiologists 一项评估由麻醉师报告的危急事件的意识和实践的调查结果

IF 1.1 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Healthcare Quality Research

Pub Date : 2025-06-13 DOI: 10.1016/j.jhqr.2025.101147

S. Kaniyil , P. Pavithran , A.K. Arun Krishna , M.C. Rajesh

Background and objectives

Enhancing patient safety in Anaesthesia relies significantly on critical incident reporting and analysis. We did an online web-based survey aiming to evaluate the awareness and practices of our anaesthesiologists on critical incident reporting in India.

Materials and methods

A validated questionnaire was disseminated via online social media platforms to evaluate the awareness and current practices of anaesthesiologists on incident reporting and analysis. Timely reminders were issued to enhance response rates, and data analyzed upon receipt of sufficient responses.

Results

Among the 506 responses received, 60% reported having a workplace incident reporting system. Despite high awareness, a significant majority expressed reluctance to report incidents, citing the fear of blame and shame as a deterrent. The most frequently reported incidents included cardiac arrest and drug errors. Identified contributing factors included inadequate staffing, communication gaps, prolonged work hours, a stressful work environment, and the absence of institutional protocols.

Conclusions

Despite a notable level of awareness regarding critical incident reporting among our anaesthesiologists, apprehensions related to blame and finger-pointing hinder the reporting process. As a uniform reporting system is lacking, formulating a national guideline, and establishing a standard reporting system is the need of the hour.

背景和目的增强麻醉患者安全在很大程度上依赖于关键事件的报告和分析。我们做了一个基于网络的在线调查，旨在评估我们的麻醉师对印度重大事件报告的认识和实践。材料和方法通过在线社交媒体平台分发一份经过验证的问卷，以评估麻醉师对事件报告和分析的认识和当前做法。及时发出提醒以提高回应率，并在收到足够回应后分析数据。结果在收到的506份回复中，60%的受访者表示拥有工作场所事件报告系统。尽管有很高的意识，但绝大多数人表示不愿报告这些事件，理由是害怕受到指责和羞辱。最常见的报告事件包括心脏骤停和药物错误。确定的促成因素包括人员配备不足、沟通差距、工作时间延长、工作环境紧张以及缺乏机构协议。尽管我们的麻醉师对危急事件报告的认识程度很高，但与指责和指责有关的担忧阻碍了报告过程。由于缺乏统一的报告制度，制定全国性的指导方针，建立规范的报告制度是当务之急。

{"title":"Results of a survey to evaluate awareness and practices of critical incident reported by anaesthesiologists","authors":"S. Kaniyil , P. Pavithran , A.K. Arun Krishna , M.C. Rajesh","doi":"10.1016/j.jhqr.2025.101147","DOIUrl":"10.1016/j.jhqr.2025.101147","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Enhancing patient safety in Anaesthesia relies significantly on critical incident reporting and analysis. We did an online web-based survey aiming to evaluate the awareness and practices of our anaesthesiologists on critical incident reporting in India.</div></div><div><h3>Materials and methods</h3><div>A validated questionnaire was disseminated via online social media platforms to evaluate the awareness and current practices of anaesthesiologists on incident reporting and analysis. Timely reminders were issued to enhance response rates, and data analyzed upon receipt of sufficient responses.</div></div><div><h3>Results</h3><div>Among the 506 responses received, 60% reported having a workplace incident reporting system. Despite high awareness, a significant majority expressed reluctance to report incidents, citing the fear of blame and shame as a deterrent. The most frequently reported incidents included cardiac arrest and drug errors. Identified contributing factors included inadequate staffing, communication gaps, prolonged work hours, a stressful work environment, and the absence of institutional protocols.</div></div><div><h3>Conclusions</h3><div>Despite a notable level of awareness regarding critical incident reporting among our anaesthesiologists, apprehensions related to blame and finger-pointing hinder the reporting process. As a uniform reporting system is lacking, formulating a national guideline, and establishing a standard reporting system is the need of the hour.</div></div>","PeriodicalId":37347,"journal":{"name":"Journal of Healthcare Quality Research","volume":"40 6","pages":"Article 101147"},"PeriodicalIF":1.1,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Healthcare-associated infections in a long-term care hospital: A three-year point-prevalence study 长期护理医院的医疗保健相关感染：一项为期三年的点流行研究

IF 1.1 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Healthcare Quality Research

Pub Date : 2025-06-09 DOI: 10.1016/j.jhqr.2025.101146

P. Cárdenas-Soriano , V.S.H. Múgica , P. Blanco-Hernández , M. Gil-López , G. Rodríguez-Caravaca , A.M. Pedraza-Flechas

Objective

To assess the prevalence of Healthcare-Associated Infections (HAIs) acquired during hospitalization in a long-term care (LTC) hospital during three periods and identify associated factors.

Methods

An observational, cross-sectional study had been conducted in 2019, 2021, and 2023 that included 380 patients. Data collected encompassed demographics, presence of risk factors (pressure sores, catheters, surgery), and HAIs acquired in the current hospitalization. Global and per location HAI was determined, and bivariate and a multiple logistic regression model was constructed to explore the association between the studied variables and infection.

Results

The median age varied depending on the year of the survey between 77 and 80.5 years, and the proportion of female patients increased each edition. Length of stay peaked in 2021 (43.5 days), and risk factors in 2023. HAIs prevalences were 8.4% (2019), 10.7% (2021), and 5.6% (2023). Respiratory tract infection was the most frequent globally (34.4%), in 2019 (35.7%) and 2023 (50.0%), followed by urinary tract infection. Globally, HAI and any risk factor (OR: 3.8, 95% CI: 1.6–8.8), and pressure sores (OR: 2.4, 95% CI: 1.1–5.2) were associated, this last remained after adjustment (OR: 16.0, 95% CI: 2.5–104.9).

Conclusions

LTC hospitals pose a risk for HAI. Further research on associated factors and preventive strategies is crucial to improve care in this sector.

目的评估某长期护理医院住院期间获得性卫生保健相关感染（HAIs）的流行情况，并确定相关因素。方法于2019年、2021年和2023年进行了一项观察性横断面研究，包括380例患者。收集的数据包括人口统计、风险因素（压疮、导尿管、手术）的存在以及当前住院期间获得的卫生保健指数。确定了全球和每个地点的HAI，并构建了双变量和多元逻辑回归模型，以探讨所研究变量与感染之间的关系。结果不同年份患者年龄中位数在77 ~ 80.5岁之间，女性患者所占比例逐年增加。停留时间在2021年达到峰值（43.5天），风险因素在2023年达到峰值。HAIs患病率分别为8.4%（2019年）、10.7%（2021年）和5.6%（2023年）。全球最常见的是呼吸道感染（34.4%），2019年（35.7%）和2023年（50.0%），其次是尿路感染。总体而言，HAI与任何危险因素（OR: 3.8, 95% CI: 1.6-8.8）和压疮（OR: 2.4, 95% CI: 1.1-5.2）相关，最后一个因素在调整后仍然存在（OR: 16.0, 95% CI: 2.5-104.9）。结论sltc医院存在HAI风险。进一步研究相关因素和预防战略对于改善这一部门的护理至关重要。

{"title":"Healthcare-associated infections in a long-term care hospital: A three-year point-prevalence study","authors":"P. Cárdenas-Soriano , V.S.H. Múgica , P. Blanco-Hernández , M. Gil-López , G. Rodríguez-Caravaca , A.M. Pedraza-Flechas","doi":"10.1016/j.jhqr.2025.101146","DOIUrl":"10.1016/j.jhqr.2025.101146","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the prevalence of Healthcare-Associated Infections (HAIs) acquired during hospitalization in a long-term care (LTC) hospital during three periods and identify associated factors.</div></div><div><h3>Methods</h3><div>An observational, cross-sectional study had been conducted in 2019, 2021, and 2023 that included 380 patients. Data collected encompassed demographics, presence of risk factors (pressure sores, catheters, surgery), and HAIs acquired in the current hospitalization. Global and per location HAI was determined, and bivariate and a multiple logistic regression model was constructed to explore the association between the studied variables and infection.</div></div><div><h3>Results</h3><div>The median age varied depending on the year of the survey between 77 and 80.5 years, and the proportion of female patients increased each edition. Length of stay peaked in 2021 (43.5 days), and risk factors in 2023. HAIs prevalences were 8.4% (2019), 10.7% (2021), and 5.6% (2023). Respiratory tract infection was the most frequent globally (34.4%), in 2019 (35.7%) and 2023 (50.0%), followed by urinary tract infection. Globally, HAI and any risk factor (OR: 3.8, 95% CI: 1.6–8.8), and pressure sores (OR: 2.4, 95% CI: 1.1–5.2) were associated, this last remained after adjustment (OR: 16.0, 95% CI: 2.5–104.9).</div></div><div><h3>Conclusions</h3><div>LTC hospitals pose a risk for HAI. Further research on associated factors and preventive strategies is crucial to improve care in this sector.</div></div>","PeriodicalId":37347,"journal":{"name":"Journal of Healthcare Quality Research","volume":"40 6","pages":"Article 101146"},"PeriodicalIF":1.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144243553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison and analysis of biological drug consumption in two Italian hospital settings: Governance actions and prescribing appropriateness 比较和分析两家意大利医院的生物药物消费：治理行动和处方适当性

IF 1.1 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Healthcare Quality Research

Pub Date : 2025-06-09 DOI: 10.1016/j.jhqr.2025.101148

M. Vaccaro , G. Polito , G. Bagaglini , M. Capuozzo , R. Langella , E. Nava , A. Zovi , F. Ferrara

Background

Biosimilar drugs represent a valuable opportunity for healthcare systems worldwide, offering substantial cost savings while ensuring equivalent efficacy and safety in treating chronic conditions. These savings can be reinvested in ongoing medical innovation.

Methods

An investigation was carried out to evaluate the utilization of key biologic therapies across various clinical indications within two Italian healthcare institutions: Asl Napoli 3 Sud and Policlinico Umberto I in Rome. Information regarding consumption and expenditure was extracted from institutional databases. A comparison with figures from 2021 was conducted to detect any growth in biosimilar adoption throughout 2022.

Results

The 2022 review demonstrated that most of the examined compounds were administered predominantly as biosimilars, with proportions nearing complete substitution, aside from some notable outliers. In particular, reluctance persisted in prescribing biosimilar adalimumab (73.8%) and etanercept (73.3%) at Asl Napoli 3 Sud, as well as erythropoietin (69.5%) and rituximab (72.8%) at Policlinico Umberto I.

Conclusion

The year-on-year comparison between 2021 and 2022 underscored a growing shift toward biosimilar prescriptions. This favorable direction indicates the likelihood of reaching full implementation soon, with meaningful advantages for the National Healthcare Service and citizens, promoting an efficient and economically viable model of care.

生物仿制药为全球医疗保健系统提供了一个宝贵的机会，在确保治疗慢性疾病的同等功效和安全性的同时，提供了大量的成本节约。这些节省下来的资金可以再投资于正在进行的医疗创新。方法开展一项调查，评估两家意大利医疗机构（那不勒斯3 Sud医院和罗马Umberto I医院）在各种临床适应症中关键生物疗法的使用情况。有关消费和支出的资料摘自机构数据库。与2021年的数据进行比较，以检测整个2022年生物仿制药采用的增长情况。结果2022年的审查表明，除了一些显著的异常值外，大多数被检查的化合物主要作为生物类似药给药，比例接近完全替代。特别是，在Asl Napoli 3 Sud，不愿开生物仿制药阿达木单抗（73.8%）和依那西普（73.3%），以及在Policlinico Umberto i，不愿开促红细胞生成素（69.5%）和利妥昔单抗（72.8%）。结论2021年和2022年的同比比较表明，越来越多的人转向开生物仿制药。这一有利的方向表明，很快就有可能全面实施，对国家医疗保健服务和公民有意义的好处，促进一种高效和经济上可行的护理模式。

{"title":"Comparison and analysis of biological drug consumption in two Italian hospital settings: Governance actions and prescribing appropriateness","authors":"M. Vaccaro , G. Polito , G. Bagaglini , M. Capuozzo , R. Langella , E. Nava , A. Zovi , F. Ferrara","doi":"10.1016/j.jhqr.2025.101148","DOIUrl":"10.1016/j.jhqr.2025.101148","url":null,"abstract":"<div><h3>Background</h3><div>Biosimilar drugs represent a valuable opportunity for healthcare systems worldwide, offering substantial cost savings while ensuring equivalent efficacy and safety in treating chronic conditions. These savings can be reinvested in ongoing medical innovation.</div></div><div><h3>Methods</h3><div>An investigation was carried out to evaluate the utilization of key biologic therapies across various clinical indications within two Italian healthcare institutions: Asl Napoli 3 Sud and Policlinico Umberto I in Rome. Information regarding consumption and expenditure was extracted from institutional databases. A comparison with figures from 2021 was conducted to detect any growth in biosimilar adoption throughout 2022.</div></div><div><h3>Results</h3><div>The 2022 review demonstrated that most of the examined compounds were administered predominantly as biosimilars, with proportions nearing complete substitution, aside from some notable outliers. In particular, reluctance persisted in prescribing biosimilar adalimumab (73.8%) and etanercept (73.3%) at Asl Napoli 3 Sud, as well as erythropoietin (69.5%) and rituximab (72.8%) at Policlinico Umberto I.</div></div><div><h3>Conclusion</h3><div>The year-on-year comparison between 2021 and 2022 underscored a growing shift toward biosimilar prescriptions. This favorable direction indicates the likelihood of reaching full implementation soon, with meaningful advantages for the National Healthcare Service and citizens, promoting an efficient and economically viable model of care.</div></div>","PeriodicalId":37347,"journal":{"name":"Journal of Healthcare Quality Research","volume":"40 6","pages":"Article 101148"},"PeriodicalIF":1.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144243489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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