Pub Date : 2021-03-23DOI: 10.1007/s40475-021-00228-3
C. Infante-Fernández, M. Toledo-Bahena, A. Valencia-Herrera
{"title":"Cutaneous Mycobacterial Infections in Returning Travelers","authors":"C. Infante-Fernández, M. Toledo-Bahena, A. Valencia-Herrera","doi":"10.1007/s40475-021-00228-3","DOIUrl":"https://doi.org/10.1007/s40475-021-00228-3","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"8 1","pages":"81 - 90"},"PeriodicalIF":5.4,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40475-021-00228-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45895075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-25DOI: 10.1007/s40475-021-00234-5
S. Gaba, Monica Gupta, R. Gaba, S. Lehl
{"title":"Scrub Typhus: an Update*","authors":"S. Gaba, Monica Gupta, R. Gaba, S. Lehl","doi":"10.1007/s40475-021-00234-5","DOIUrl":"https://doi.org/10.1007/s40475-021-00234-5","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"8 1","pages":"133-140"},"PeriodicalIF":5.4,"publicationDate":"2021-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40475-021-00234-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42274623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-22DOI: 10.1007/s40475-021-00226-5
Flóra Bohner, A. Gácser, R. Tóth
{"title":"Epidemiological Attributes of Candida Species in Tropical Regions","authors":"Flóra Bohner, A. Gácser, R. Tóth","doi":"10.1007/s40475-021-00226-5","DOIUrl":"https://doi.org/10.1007/s40475-021-00226-5","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"1 1","pages":"1-10"},"PeriodicalIF":5.4,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40475-021-00226-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47960595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-11DOI: 10.1007/s40475-020-00225-y
F. Guhl, J. Ramírez
{"title":"Poverty, Migration, and Chagas Disease","authors":"F. Guhl, J. Ramírez","doi":"10.1007/s40475-020-00225-y","DOIUrl":"https://doi.org/10.1007/s40475-020-00225-y","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"8 1","pages":"52-58"},"PeriodicalIF":5.4,"publicationDate":"2021-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40475-020-00225-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46560494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-04DOI: 10.1007/s40475-020-00220-3
M. da Silva Ferreira, Diego de Souza Gonçalves, Elisa Gonçalves Medeiros, J. M. Peralta, A. Guimarães
{"title":"“Feast-Fit-Fist-Feat”: Overview of Free-living Amoeba Interactions with Fungi and Virulence as a Foundation for Success in Battle","authors":"M. da Silva Ferreira, Diego de Souza Gonçalves, Elisa Gonçalves Medeiros, J. M. Peralta, A. Guimarães","doi":"10.1007/s40475-020-00220-3","DOIUrl":"https://doi.org/10.1007/s40475-020-00220-3","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"1 1","pages":"1-14"},"PeriodicalIF":5.4,"publicationDate":"2021-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40475-020-00220-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45272705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-03-16DOI: 10.1007/s40475-021-00235-4
Paul A Kuehnert, Christopher P Stefan, Catherine V Badger, Keersten M Ricks
Purpose of review: This review is aimed at highlighting recent research and articles on the complicated relationship between virus, vector, and host and how biosurveillance at each level informs disease spread and risk.
Recent findings: While human cases of CCHFV and tick identification in non-endemic areas in 2019-2020 were reported to sites such as ProMed, there is a gap in recent published literature on these and broader CCHFV surveillance efforts from the late 2010s.
Summary: A review of the complex aspects of CCHFV maintenance in the environment coupled with high fatality rate and lack of vaccines and therapeutics warrants the need for a One-Health approach toward detection and increased biosurveillance programs for CCHFV.
{"title":"Crimean-Congo Hemorrhagic Fever Virus (CCHFV): A Silent but Widespread Threat.","authors":"Paul A Kuehnert, Christopher P Stefan, Catherine V Badger, Keersten M Ricks","doi":"10.1007/s40475-021-00235-4","DOIUrl":"https://doi.org/10.1007/s40475-021-00235-4","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review is aimed at highlighting recent research and articles on the complicated relationship between virus, vector, and host and how biosurveillance at each level informs disease spread and risk.</p><p><strong>Recent findings: </strong>While human cases of CCHFV and tick identification in non-endemic areas in 2019-2020 were reported to sites such as ProMed, there is a gap in recent published literature on these and broader CCHFV surveillance efforts from the late 2010s.</p><p><strong>Summary: </strong>A review of the complex aspects of CCHFV maintenance in the environment coupled with high fatality rate and lack of vaccines and therapeutics warrants the need for a One-Health approach toward detection and increased biosurveillance programs for CCHFV.</p>","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"8 2","pages":"141-147"},"PeriodicalIF":5.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40475-021-00235-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25501647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-05-11DOI: 10.1007/s40475-021-00241-6
Anthony J Garcia-Prats, Ryan M McAdams, Mogomotsi Matshaba, Lineo Thahane, Sabrina M Butteris, James H Conway, Mandy Slutsker, Nicole E St Clair, Heather Haq
Purpose of review: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), continues to affect individuals, communities, and health systems worldwide. Here, we highlight how COVID-19 threatens to jeopardize the tremendous gains made over the last few decades on improving children's health globally.
Recent findings: In contrast to adults, children with COVID-19 are less likely to develop severe disease requiring hospitalization or die as a direct result of infection. However, the pandemic will likely have other important health impacts disproportionately affecting vulnerable children globally. Possible effects include worsening of poverty and food insecurity; disruption of already strained routine child health services; damage to already imperiled healthcare workforces; a wave of mental health challenges; interruption of education; and increased risks of violence, abuse, exploitation, and neglect. These challenges notwithstanding, the response to COVID-19 may also provide opportunities, such as for health system strengthening, that could improve child health after the pandemic.
Summary: The negative impacts of COVID-19 on global child health may be substantial. However, these are not foregone conclusions and much can be done to mitigate the worst outcomes. Child health providers should advocate for an equitable response to COVID-19 that prioritizes the health of vulnerable children and furthers the gains made in global child health.
{"title":"Mitigating the Impacts of COVID-19 on Global Child Health: a Call to Action.","authors":"Anthony J Garcia-Prats, Ryan M McAdams, Mogomotsi Matshaba, Lineo Thahane, Sabrina M Butteris, James H Conway, Mandy Slutsker, Nicole E St Clair, Heather Haq","doi":"10.1007/s40475-021-00241-6","DOIUrl":"https://doi.org/10.1007/s40475-021-00241-6","url":null,"abstract":"<p><strong>Purpose of review: </strong>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), continues to affect individuals, communities, and health systems worldwide. Here, we highlight how COVID-19 threatens to jeopardize the tremendous gains made over the last few decades on improving children's health globally.</p><p><strong>Recent findings: </strong>In contrast to adults, children with COVID-19 are less likely to develop severe disease requiring hospitalization or die as a direct result of infection. However, the pandemic will likely have other important health impacts disproportionately affecting vulnerable children globally. Possible effects include worsening of poverty and food insecurity; disruption of already strained routine child health services; damage to already imperiled healthcare workforces; a wave of mental health challenges; interruption of education; and increased risks of violence, abuse, exploitation, and neglect. These challenges notwithstanding, the response to COVID-19 may also provide opportunities, such as for health system strengthening, that could improve child health after the pandemic.</p><p><strong>Summary: </strong>The negative impacts of COVID-19 on global child health may be substantial. However, these are not foregone conclusions and much can be done to mitigate the worst outcomes. Child health providers should advocate for an equitable response to COVID-19 that prioritizes the health of vulnerable children and furthers the gains made in global child health.</p>","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"8 3","pages":"183-189"},"PeriodicalIF":5.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40475-021-00241-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38986681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1007/s40475-020-00222-1
Berenice Morales-Franco, Mario Nava-Villalba, Edgar Octavio Medina-Guerrero, Yaír Adonaí Sánchez-Nuño, Perla Davila-Villa, Elsa Janneth Anaya-Ambriz, Claudia Lisette Charles-Niño
Purpose of review: Infectious diseases represent up to 12% of all deaths in people with diabetes mellitus (DM). The development and progression of DM generate a chronic inflammatory state with unique characteristics that have been exploited by some pathogens; one of them is Rhizopus spp., a fungus considered the causative agent of mucormycosis. This disease has a poor prognosis with high mortality rates, and the apparition of resistant isolates each year has become a worrying concern. DM is an actual and continuing health problem, and for that reason, it is of foremost importance to study the pathogenesis of mucormycosis to generate new prevention and treatment strategies.
Recent findings: The worldwide incidence of mucormycosis has increased in recent years. The pathogenic mechanisms and factors identified in Rhizopus spp. are the cell wall, spore germination, proteins, and enzymes related to iron sequestration, CotH fungal protein, positive regulation of the GRP78 cell receptor, and immune evasion due to survival within phagocytes, among others. The physiopathology of DM offers favorable conditions for the successful replication of Rhizopus spp.
Summary: The main reason for increase of incidence of mucormycosis caused by Rhizopus spp. has been associated with the rise of worldwide prevalence of DM. Knowing the fungal pathogenic mechanisms as well as the relationships between Rhizopus with the microenvironment found in the human body will undoubtedly help generate better antifungals to enhance treatment outcomes. Nowadays, some strategies to combat the fungus are based on the knowledge of its proteins, cellular interactions, and iron metabolism.
{"title":"Host-Pathogen Molecular Factors Contribute to the Pathogenesis of <i>Rhizopus</i> spp. in Diabetes Mellitus.","authors":"Berenice Morales-Franco, Mario Nava-Villalba, Edgar Octavio Medina-Guerrero, Yaír Adonaí Sánchez-Nuño, Perla Davila-Villa, Elsa Janneth Anaya-Ambriz, Claudia Lisette Charles-Niño","doi":"10.1007/s40475-020-00222-1","DOIUrl":"https://doi.org/10.1007/s40475-020-00222-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>Infectious diseases represent up to 12% of all deaths in people with diabetes mellitus (DM). The development and progression of DM generate a chronic inflammatory state with unique characteristics that have been exploited by some pathogens; one of them is <i>Rhizopus</i> spp., a fungus considered the causative agent of mucormycosis. This disease has a poor prognosis with high mortality rates, and the apparition of resistant isolates each year has become a worrying concern. DM is an actual and continuing health problem, and for that reason, it is of foremost importance to study the pathogenesis of mucormycosis to generate new prevention and treatment strategies.</p><p><strong>Recent findings: </strong>The worldwide incidence of mucormycosis has increased in recent years. The pathogenic mechanisms and factors identified in <i>Rhizopus</i> spp. are the cell wall, spore germination, proteins, and enzymes related to iron sequestration, CotH fungal protein, positive regulation of the GRP78 cell receptor, and immune evasion due to survival within phagocytes, among others. The physiopathology of DM offers favorable conditions for the successful replication of <i>Rhizopus</i> spp.</p><p><strong>Summary: </strong>The main reason for increase of incidence of mucormycosis caused by <i>Rhizopus</i> spp. has been associated with the rise of worldwide prevalence of DM. Knowing the fungal pathogenic mechanisms as well as the relationships between <i>Rhizopus</i> with the microenvironment found in the human body will undoubtedly help generate better antifungals to enhance treatment outcomes. Nowadays, some strategies to combat the fungus are based on the knowledge of its proteins, cellular interactions, and iron metabolism.</p>","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"8 1","pages":"6-17"},"PeriodicalIF":5.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40475-020-00222-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10630585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-03-29DOI: 10.1007/s40475-021-00238-1
Sayed A Quadri, Prasad R Padala
Purpose of review: Kumbh Mela, a religious gathering of Hindus held in India, is the largest massive gathering event in the world. The COVID-19 pandemic is an unprecedented healthcare crisis in recent times with effects reverberating in all spheres of human lives. India has registered the second highest number of COVID-19 cases. This paper aims to dwell in the religious and social background of Kumbh Mela massive gathering, as well as the ritualistic practices that could potentially entail public health risks in the current situation. It also aims to identify possible preparatory and interventional measures to evade such risks.
Recent findings: In recent years, the increase in the number of people attending the Kumbh Mela has been phenomenal. Congregants are put up at the holy sites for several days. The sheer number of people assembling at the religious venues poses a great challenge to manage the crowds, to cater to the requirements of basic amenities, and to meet their healthcare needs. Some of the ritualistic practices could heighten the risk for transmission of respiratory pathogens. The COVID-19 pandemic has escalated over the past few months in India. The pandemic is expected to sustain its tempo in India throughout the foreseeable future. Organization of the forthcoming Kumbh Mela needs meticulous planning.
Summary: Kumbh Mela is a Hindu religious gathering at the banks of India's rivers, held periodically. It witnesses assembly of huge numbers of people and has the potential to amplify the COVID-19 pandemic in India; this could overwhelm the healthcare system.
{"title":"An Aspect of <i>Kumbh Mela</i> Massive Gathering and COVID-19.","authors":"Sayed A Quadri, Prasad R Padala","doi":"10.1007/s40475-021-00238-1","DOIUrl":"https://doi.org/10.1007/s40475-021-00238-1","url":null,"abstract":"<p><strong>Purpose of review: </strong><i>Kumbh Mela</i>, a religious gathering of Hindus held in India, is the largest massive gathering event in the world. The COVID-19 pandemic is an unprecedented healthcare crisis in recent times with effects reverberating in all spheres of human lives. India has registered the second highest number of COVID-19 cases. This paper aims to dwell in the religious and social background of <i>Kumbh Mela</i> massive gathering, as well as the ritualistic practices that could potentially entail public health risks in the current situation. It also aims to identify possible preparatory and interventional measures to evade such risks.</p><p><strong>Recent findings: </strong>In recent years, the increase in the number of people attending the <i>Kumbh Mela</i> has been phenomenal. Congregants are put up at the holy sites for several days. The sheer number of people assembling at the religious venues poses a great challenge to manage the crowds, to cater to the requirements of basic amenities, and to meet their healthcare needs. Some of the ritualistic practices could heighten the risk for transmission of respiratory pathogens. The COVID-19 pandemic has escalated over the past few months in India. The pandemic is expected to sustain its tempo in India throughout the foreseeable future. Organization of the forthcoming <i>Kumbh Mela</i> needs meticulous planning.</p><p><strong>Summary: </strong><i>Kumbh Mela</i> is a Hindu religious gathering at the banks of India's rivers, held periodically. It witnesses assembly of huge numbers of people and has the potential to amplify the COVID-19 pandemic in India; this could overwhelm the healthcare system.</p>","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"8 3","pages":"225-230"},"PeriodicalIF":5.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40475-021-00238-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25558639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}