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Cutaneous Mycobacterial Infections in Returning Travelers 回国旅客皮肤分枝杆菌感染
IF 5.4 Q2 INFECTIOUS DISEASES Pub Date : 2021-03-23 DOI: 10.1007/s40475-021-00228-3
C. Infante-Fernández, M. Toledo-Bahena, A. Valencia-Herrera
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引用次数: 0
Scrub Typhus: an Update* 恙虫病:最新情况*
IF 5.4 Q2 INFECTIOUS DISEASES Pub Date : 2021-02-25 DOI: 10.1007/s40475-021-00234-5
S. Gaba, Monica Gupta, R. Gaba, S. Lehl
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引用次数: 2
Myiasis and Tungiasis 蝇蛆病和舌虫病
IF 5.4 Q2 INFECTIOUS DISEASES Pub Date : 2021-02-23 DOI: 10.1007/s40475-021-00233-6
Johanna Osorio-Pinzon, Angélica Palencia, Stefania Cruz-Calderón, A. Rodríguez-Morales
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引用次数: 1
Epidemiological Attributes of Candida Species in Tropical Regions 热带地区念珠菌的流行病学特征
IF 5.4 Q2 INFECTIOUS DISEASES Pub Date : 2021-01-22 DOI: 10.1007/s40475-021-00226-5
Flóra Bohner, A. Gácser, R. Tóth
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引用次数: 3
Poverty, Migration, and Chagas Disease 贫困、移民和南美锥虫病
IF 5.4 Q2 INFECTIOUS DISEASES Pub Date : 2021-01-11 DOI: 10.1007/s40475-020-00225-y
F. Guhl, J. Ramírez
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引用次数: 17
“Feast-Fit-Fist-Feat”: Overview of Free-living Amoeba Interactions with Fungi and Virulence as a Foundation for Success in Battle “盛宴-拳头-壮举”:概述自由生活的阿米巴与真菌和毒力的相互作用,作为战斗成功的基础
IF 5.4 Q2 INFECTIOUS DISEASES Pub Date : 2021-01-04 DOI: 10.1007/s40475-020-00220-3
M. da Silva Ferreira, Diego de Souza Gonçalves, Elisa Gonçalves Medeiros, J. M. Peralta, A. Guimarães
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引用次数: 4
Crimean-Congo Hemorrhagic Fever Virus (CCHFV): A Silent but Widespread Threat. 克里米亚-刚果出血热病毒(CCHFV):无声但广泛的威胁。
IF 5.4 Q2 INFECTIOUS DISEASES Pub Date : 2021-01-01 Epub Date: 2021-03-16 DOI: 10.1007/s40475-021-00235-4
Paul A Kuehnert, Christopher P Stefan, Catherine V Badger, Keersten M Ricks

Purpose of review: This review is aimed at highlighting recent research and articles on the complicated relationship between virus, vector, and host and how biosurveillance at each level informs disease spread and risk.

Recent findings: While human cases of CCHFV and tick identification in non-endemic areas in 2019-2020 were reported to sites such as ProMed, there is a gap in recent published literature on these and broader CCHFV surveillance efforts from the late 2010s.

Summary: A review of the complex aspects of CCHFV maintenance in the environment coupled with high fatality rate and lack of vaccines and therapeutics warrants the need for a One-Health approach toward detection and increased biosurveillance programs for CCHFV.

综述目的:本综述旨在重点介绍病毒、媒介和宿主之间复杂关系的最新研究和文章,以及各个层面的生物监测如何为疾病传播和风险提供信息。最近的发现:虽然2019-2020年在非流行地区报告了CCHFV人间病例和蜱虫鉴定,但最近发表的关于这些病例和2010年代末以来更广泛的CCHFV监测工作的文献存在空白。总结:对CCHFV在环境中维持的复杂方面的回顾,加上高致死率和缺乏疫苗和治疗方法,证明有必要采取一种单一健康的方法来检测和增加CCHFV的生物监测计划。
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引用次数: 19
Mitigating the Impacts of COVID-19 on Global Child Health: a Call to Action. 减轻COVID-19对全球儿童健康的影响:行动呼吁。
IF 5.4 Q2 INFECTIOUS DISEASES Pub Date : 2021-01-01 Epub Date: 2021-05-11 DOI: 10.1007/s40475-021-00241-6
Anthony J Garcia-Prats, Ryan M McAdams, Mogomotsi Matshaba, Lineo Thahane, Sabrina M Butteris, James H Conway, Mandy Slutsker, Nicole E St Clair, Heather Haq

Purpose of review: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), continues to affect individuals, communities, and health systems worldwide. Here, we highlight how COVID-19 threatens to jeopardize the tremendous gains made over the last few decades on improving children's health globally.

Recent findings: In contrast to adults, children with COVID-19 are less likely to develop severe disease requiring hospitalization or die as a direct result of infection. However, the pandemic will likely have other important health impacts disproportionately affecting vulnerable children globally. Possible effects include worsening of poverty and food insecurity; disruption of already strained routine child health services; damage to already imperiled healthcare workforces; a wave of mental health challenges; interruption of education; and increased risks of violence, abuse, exploitation, and neglect. These challenges notwithstanding, the response to COVID-19 may also provide opportunities, such as for health system strengthening, that could improve child health after the pandemic.

Summary: The negative impacts of COVID-19 on global child health may be substantial. However, these are not foregone conclusions and much can be done to mitigate the worst outcomes. Child health providers should advocate for an equitable response to COVID-19 that prioritizes the health of vulnerable children and furthers the gains made in global child health.

审查目的:严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)是2019年冠状病毒病(COVID-19)的病因,继续影响全世界的个人、社区和卫生系统。在此,我们强调,COVID-19有可能危及过去几十年在改善全球儿童健康方面取得的巨大成就。最新发现:与成人相比,感染COVID-19的儿童不太可能发展为需要住院治疗的严重疾病或因感染而直接死亡。然而,这场大流行病可能会对全球弱势儿童产生其他严重的健康影响。可能的影响包括贫困和粮食不安全状况的恶化;中断本已紧张的常规儿童保健服务;对已经岌岌可危的医护人员造成损害;一波心理健康挑战;中断教育;暴力、虐待、剥削和忽视的风险也在增加。尽管存在这些挑战,但应对COVID-19也可能提供机会,例如加强卫生系统,从而改善大流行后的儿童健康。摘要:COVID-19对全球儿童健康的负面影响可能是巨大的。然而,这些并不是必然的结论,可以做很多事情来减轻最坏的结果。儿童卫生服务提供者应倡导公平应对COVID-19,优先考虑弱势儿童的健康,并进一步促进全球儿童卫生方面取得的成果。
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引用次数: 8
Host-Pathogen Molecular Factors Contribute to the Pathogenesis of Rhizopus spp. in Diabetes Mellitus. 糖尿病根霉致病机制的宿主-病原体分子因素研究。
IF 5.4 Q2 INFECTIOUS DISEASES Pub Date : 2021-01-01 DOI: 10.1007/s40475-020-00222-1
Berenice Morales-Franco, Mario Nava-Villalba, Edgar Octavio Medina-Guerrero, Yaír Adonaí Sánchez-Nuño, Perla Davila-Villa, Elsa Janneth Anaya-Ambriz, Claudia Lisette Charles-Niño

Purpose of review: Infectious diseases represent up to 12% of all deaths in people with diabetes mellitus (DM). The development and progression of DM generate a chronic inflammatory state with unique characteristics that have been exploited by some pathogens; one of them is Rhizopus spp., a fungus considered the causative agent of mucormycosis. This disease has a poor prognosis with high mortality rates, and the apparition of resistant isolates each year has become a worrying concern. DM is an actual and continuing health problem, and for that reason, it is of foremost importance to study the pathogenesis of mucormycosis to generate new prevention and treatment strategies.

Recent findings: The worldwide incidence of mucormycosis has increased in recent years. The pathogenic mechanisms and factors identified in Rhizopus spp. are the cell wall, spore germination, proteins, and enzymes related to iron sequestration, CotH fungal protein, positive regulation of the GRP78 cell receptor, and immune evasion due to survival within phagocytes, among others. The physiopathology of DM offers favorable conditions for the successful replication of Rhizopus spp.

Summary: The main reason for increase of incidence of mucormycosis caused by Rhizopus spp. has been associated with the rise of worldwide prevalence of DM. Knowing the fungal pathogenic mechanisms as well as the relationships between Rhizopus with the microenvironment found in the human body will undoubtedly help generate better antifungals to enhance treatment outcomes. Nowadays, some strategies to combat the fungus are based on the knowledge of its proteins, cellular interactions, and iron metabolism.

综述目的:传染病占糖尿病(DM)患者死亡总数的12%。糖尿病的发展和进展产生一种具有独特特征的慢性炎症状态,已被一些病原体利用;其中之一是根霉,一种被认为是毛霉病的病原体的真菌。该病预后差,死亡率高,每年出现的耐药分离株已成为令人担忧的问题。糖尿病是一个现实的、持续的健康问题,因此,研究毛霉病的发病机制对制定新的预防和治疗策略至关重要。近年来,毛霉病在世界范围内的发病率有所上升。根霉的致病机制和因素包括细胞壁、孢子萌发、铁固相关的蛋白质和酶、CotH真菌蛋白、GRP78细胞受体的正调控、吞噬细胞内生存的免疫逃避等。摘要:根霉引起的毛霉病发病率增加的主要原因与全球范围内糖尿病患病率的上升有关,了解真菌致病机制以及根霉与人体内微环境的关系,无疑将有助于产生更好的抗真菌药物,提高治疗效果。如今,一些对抗真菌的策略是基于对其蛋白质、细胞相互作用和铁代谢的了解。
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引用次数: 54
An Aspect of Kumbh Mela Massive Gathering and COVID-19. 大壶大聚会与新冠疫情的一个侧面。
IF 5.4 Q2 INFECTIOUS DISEASES Pub Date : 2021-01-01 Epub Date: 2021-03-29 DOI: 10.1007/s40475-021-00238-1
Sayed A Quadri, Prasad R Padala

Purpose of review: Kumbh Mela, a religious gathering of Hindus held in India, is the largest massive gathering event in the world. The COVID-19 pandemic is an unprecedented healthcare crisis in recent times with effects reverberating in all spheres of human lives. India has registered the second highest number of COVID-19 cases. This paper aims to dwell in the religious and social background of Kumbh Mela massive gathering, as well as the ritualistic practices that could potentially entail public health risks in the current situation. It also aims to identify possible preparatory and interventional measures to evade such risks.

Recent findings: In recent years, the increase in the number of people attending the Kumbh Mela has been phenomenal. Congregants are put up at the holy sites for several days. The sheer number of people assembling at the religious venues poses a great challenge to manage the crowds, to cater to the requirements of basic amenities, and to meet their healthcare needs. Some of the ritualistic practices could heighten the risk for transmission of respiratory pathogens. The COVID-19 pandemic has escalated over the past few months in India. The pandemic is expected to sustain its tempo in India throughout the foreseeable future. Organization of the forthcoming Kumbh Mela needs meticulous planning.

Summary: Kumbh Mela is a Hindu religious gathering at the banks of India's rivers, held periodically. It witnesses assembly of huge numbers of people and has the potential to amplify the COVID-19 pandemic in India; this could overwhelm the healthcare system.

审查目的:大壶节是印度教徒在印度举行的宗教聚会,是世界上规模最大的大型聚会活动。COVID-19大流行是近年来前所未有的卫生保健危机,其影响波及人类生活的各个领域。印度的新冠肺炎病例数量位居第二。本文旨在探讨大壶节大规模集会的宗教和社会背景,以及在当前情况下可能带来公共卫生风险的仪式习俗。它还旨在确定可能的准备和干预措施,以避免这种风险。最近的发现:近年来,参加大壶节的人数显著增加。会众被安排在圣地住上几天。聚集在宗教场所的人数众多,对管理人群、满足基本设施的要求以及满足他们的医疗保健需求构成了巨大挑战。一些仪式性的做法可能会增加呼吸道病原体传播的风险。过去几个月,印度的COVID-19大流行有所升级。预计在可预见的未来,这一流行病将在印度保持其速度。即将到来的大壶节需要精心策划。概要:大壶节是在印度河岸举行的印度教宗教聚会,定期举行。它见证了大量人群的聚集,并有可能扩大印度的COVID-19大流行;这可能会使医疗系统不堪重负。
{"title":"An Aspect of <i>Kumbh Mela</i> Massive Gathering and COVID-19.","authors":"Sayed A Quadri,&nbsp;Prasad R Padala","doi":"10.1007/s40475-021-00238-1","DOIUrl":"https://doi.org/10.1007/s40475-021-00238-1","url":null,"abstract":"<p><strong>Purpose of review: </strong><i>Kumbh Mela</i>, a religious gathering of Hindus held in India, is the largest massive gathering event in the world. The COVID-19 pandemic is an unprecedented healthcare crisis in recent times with effects reverberating in all spheres of human lives. India has registered the second highest number of COVID-19 cases. This paper aims to dwell in the religious and social background of <i>Kumbh Mela</i> massive gathering, as well as the ritualistic practices that could potentially entail public health risks in the current situation. It also aims to identify possible preparatory and interventional measures to evade such risks.</p><p><strong>Recent findings: </strong>In recent years, the increase in the number of people attending the <i>Kumbh Mela</i> has been phenomenal. Congregants are put up at the holy sites for several days. The sheer number of people assembling at the religious venues poses a great challenge to manage the crowds, to cater to the requirements of basic amenities, and to meet their healthcare needs. Some of the ritualistic practices could heighten the risk for transmission of respiratory pathogens. The COVID-19 pandemic has escalated over the past few months in India. The pandemic is expected to sustain its tempo in India throughout the foreseeable future. Organization of the forthcoming <i>Kumbh Mela</i> needs meticulous planning.</p><p><strong>Summary: </strong><i>Kumbh Mela</i> is a Hindu religious gathering at the banks of India's rivers, held periodically. It witnesses assembly of huge numbers of people and has the potential to amplify the COVID-19 pandemic in India; this could overwhelm the healthcare system.</p>","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"8 3","pages":"225-230"},"PeriodicalIF":5.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40475-021-00238-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25558639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
期刊
Current Tropical Medicine Reports
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