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Effects of mental disorders on the relationship between physical activity and bone markers among depressed patients in Germany 精神障碍对德国抑郁症患者体力活动与骨骼指标关系的影响
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.pmedr.2025.103364
Sanne Houtenbos , Yangyang He , Andrea Block , Pia-Maria Wippert

Objective

Physical activity (PHYA) positively influences bone health, but this relationship might be affected by mental disorders. Aims: (1) evaluate whether mental disorders influence bone markers and (2) whether the relationship of PHYA with bone markers is influenced by mental disorders.

Methods

A secondary data analysis of the longitudinal DEPREHA-study (Germany, 18 months, n = 208, 18-65y, ICD-10 F32.x-F33.x, collected 2015–2017) was conducted. Baseline data: sociodemographic, PHYA, depressive (BDI-II) and psychosomatic (SCL-90) symptoms; bone markers procollagen-type-1-N-propeptide (P1NP), osteocalcin (OC) and crosslaps (CTx) were analyzed. Multiple linear regressions assessed associations of depressive and psychosomatic symptoms with bone markers and moderating effects of depressive and psychosomatic symptoms on the PHYA-bone marker relationship; Mediation analyses were conducted with the PROCESS macro. All analyses were conducted in IBM SPSS (v31.0; p < 0.05).

Results

Data from n = 44 depressed participants were eligible for analysis. Significant associations of BDI-II and SCL-90 with P1NP and OC were detected. A significant moderation of SCL-90 on the relationship of PHYA with P1NP (p < 0.05), but no mediation effect of BDI-II or SCL90 on bone markers was detected.

Conclusions

Depressive and psychosomatic symptoms influence and may potentially moderate the relationship between PHYA and bone markers, which should be considered in further studies and therapeutic planning.
目的体育活动对骨骼健康有积极影响,但这种关系可能受到精神障碍的影响。目的:(1)评估精神障碍是否影响骨标志物;(2)PHYA与骨标志物的关系是否受到精神障碍的影响。方法二次资料分析纵向depreha研究(德国,18个月,n = 208, 18-65岁,ICD-10 F32.x-F33。X,收集于2015-2017年)。基线数据:社会人口学、PHYA、抑郁(BDI-II)和心身(SCL-90)症状;分析骨标志物前胶原-1- n型前肽(P1NP)、骨钙素(OC)和交叉膜(CTx)。多元线性回归评估抑郁和心身症状与骨标志物的关联,以及抑郁和心身症状对phya -骨标志物关系的调节作用;中介分析是用PROCESS宏进行的。所有分析均在IBM SPSS (v31.0; p < 0.05)中进行。结果n = 44名抑郁症参与者的数据符合分析条件。BDI-II和SCL-90与P1NP和OC有显著相关性。SCL-90对PHYA与P1NP的关系有显著调节作用(p < 0.05),但BDI-II或SCL-90对骨标志物没有中介作用。结论抑郁和心身症状影响并可能调节PHYA与骨标志物之间的关系,应在进一步的研究和治疗计划中加以考虑。
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引用次数: 0
Neighborhood spikes in drug and alcohol overdoses and subsequent suicide: A serial cross-sectional study of California ZIP codes 社区毒品和酒精过量和随后的自杀激增:加州邮政编码的一系列横断面研究
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.pmedr.2025.103358
Veronica A. Pear , Sonia L. Robinson , Julia P. Schleimer , Garen J. Wintemute , Aimée Moulin

Objective

The overdose crisis potentially increases risk factors for suicide while decreasing resources available to help those in need. This study sought to determine whether acute increases in drug or alcohol overdoses increase suicide rates.

Methods

This serial cross-sectional study used comprehensive emergency department, hospital discharge, and mortality data for ZIP-code-months in California, March 2010–December 2018 (n = 163,240). Overdose spikes were defined as ZIP-code-months with rates >2 standard deviations above expected. We used confounder-adjusted Bayesian Poisson space-time misalignment models to estimate whether overdose spikes, lagged 0–6 months, were associated with the rate of suicide (overall and by firearm involvement).

Results

Overdose spikes were identified in 6728 (4.1%) ZIP-code-months. In unadjusted models, overdose spikes were associated with same-month increases in suicide (IRR: 1.07, 95% CI: 1.02, 1.14) and non-firearm suicide (IRR: 1.09, 95% CI: 1.02, 1.17). The latter association persisted in adjusted models (IRR: 1.08, 95% CI: 1.00, 1.15), which also showed reduced firearm suicide four months following a spike (IRR: 0.90, 95% CI: 0.82, 0.99). No other associations were significant.

Conclusions

We did not find robust evidence of an association between spikes in ZIP-code-level overdoses and suicide. However, associations in unadjusted models point to a potential syndemic of overdose and suicide.
目的药物过量危机潜在地增加了自杀的危险因素,同时减少了可用于帮助有需要的人的资源。这项研究试图确定药物或酒精过量的急性增加是否会增加自杀率。方法:本系列横断面研究使用2010年3月至2018年12月加利福尼亚州邮政编码月份的急诊科、出院和死亡率综合数据(n = 163,240)。过量峰值被定义为邮政编码月,其比率高于预期2个标准差。我们使用混杂因素调整的贝叶斯泊松时空失调模型来估计过量峰值(滞后0-6个月)是否与自杀率(总体和枪支参与)相关。结果在6728个邮码月(4.1%)内发现过剂量峰。在未调整的模型中,过量峰值与当月自杀(IRR: 1.07, 95% CI: 1.02, 1.14)和非枪支自杀(IRR: 1.09, 95% CI: 1.02, 1.17)的增加有关。后一种关联在调整后的模型中持续存在(IRR: 1.08, 95% CI: 1.00, 1.15),也显示在高峰后四个月枪支自杀减少(IRR: 0.90, 95% CI: 0.82, 0.99)。其他关联不显著。结论:我们没有发现强有力的证据表明邮政编码水平的过量用药与自杀之间存在关联。然而,未经调整的模型中的关联指向了过量服用和自杀的潜在综合征。
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引用次数: 0
Corrigendum to “Cancer beliefs, risk perceptions, and health protective behaviors among people living with diabetes in the United States: Results from the Health Information National Trends Survey” [Prev. Med. Rep. 57 (2025) 103206] “美国糖尿病患者的癌症信念、风险认知和健康保护行为:来自健康信息国家趋势调查的结果”的勘误表。众议员57 (2025)103206]
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.pmedr.2025.103359
Jiamin Hu , Young-Rock Hong , Daniela Rivero-Mendoza , William T. Donahoo , Naykky Singh Ospina , Stephanie A. Staras , Elizabeth Shenkman , Rahma S. Mkuu
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引用次数: 0
Exploring the burden and contributing factors of childbirth fear in Ethiopia: A systematic review and Meta-analysis 探索埃塞俄比亚分娩恐惧的负担和影响因素:一项系统回顾和荟萃分析
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.pmedr.2026.103376
Gemeda Wakgari Kitil , Wubet Tazeb Wondie , Fikadu Wake Butta

Objective

This systematic review and meta-analysis aimed to synthesize evidence on the magnitude of childbirth-related fear and its associated factors among pregnant women in Ethiopia.

Methods

A comprehensive literature search was conducted in PubMed (January 1–15, 2025), MEDLINE (January 16–31, 2025), Web of Science (February 1–15, 2025), Google Scholar (February 16–March 31, 2025), and Google (April 1–30, 2025), following PRISMA guidelines. Seven studies met the inclusion criteria. Data extraction was performed using a standardized checklist, and statistical analyses were conducted using STATA version 14. Heterogeneity was assessed with Cochrane Q and I2 statistics, and publication bias was evaluated using Egger's and Begg's tests, supported by funnel plots.

Results

The pooled prevalence of fear of childbirth among pregnant women in Ethiopia was 26.14 % (95 % CI, 16.77, 35.51). Significant factors associated with this fear included unplanned pregnancy (OR = 4.26; 95 % CI: 1.29, 14.09), previous obstetric complications (OR = 5.51; 95 % CI: 3.34, 9.09), low educational attainment (OR = 5.82; 95 % CI: 2.57, 13.21), and the presence of medical illness (OR = 3.60; 95 % CI: 1.67, 7.78).

Conclusion

Childbirth-related fear is a substantial maternal health concern in Ethiopia. Addressing this issue requires strengthening antenatal education, integrating psychological support into routine maternity care, and ensuring culturally sensitive community involvement to improve women's confidence and childbirth experiences.
目的本系统综述和荟萃分析旨在综合埃塞俄比亚孕妇分娩相关恐惧程度及其相关因素的证据。方法根据PRISMA指南,在PubMed(2025年1月1-15日)、MEDLINE(2025年1月16-31日)、Web of Science(2025年2月1-15日)、b谷歌Scholar(2025年2月16 - 3月31日)和谷歌(2025年4月1-30日)进行综合文献检索。7项研究符合纳入标准。使用标准化检查表进行数据提取,并使用STATA版本14进行统计分析。采用Cochrane Q和I2统计量评估异质性,采用Egger's和Begg's检验评估发表偏倚,并采用漏斗图支持。结果埃塞俄比亚孕妇分娩恐惧的总患病率为26.14% (95% CI, 16.77, 35.51)。与这种恐惧相关的重要因素包括意外怀孕(OR = 4.26; 95% CI: 1.29, 14.09)、既往产科并发症(OR = 5.51; 95% CI: 3.34, 9.09)、低教育程度(OR = 5.82; 95% CI: 2.57, 13.21)和内科疾病(OR = 3.60; 95% CI: 1.67, 7.78)。结论在埃塞俄比亚,与分娩有关的恐惧是一个重要的孕产妇健康问题。解决这一问题需要加强产前教育,将心理支持纳入常规产科护理,并确保对文化敏感的社区参与,以提高妇女的信心和分娩体验。
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引用次数: 0
Generative artificial intelligence in scientific publishing: Expectations for authors and reviewers at Preventive Medicine and Preventive Medicine Reports 科学出版中的生成人工智能:对预防医学和预防医学报告作者和审稿人的期望。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.pmedr.2025.103334
Andrew W. Arthur , Alissa Moore , Luis Carmona Rosado , Pareesa Kassam , Margaret Logel , Christina I. Nieves , Parker Tope , David Litaker, Luisa N. Borrell
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引用次数: 0
Kimchi friend or foe: preserving cultural foods developed pre-refrigeration 泡菜的朋友或敌人:保存文化食品开发预冷藏
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.pmedr.2025.103357
Jeong Yun Yang , Karen E. Kim , Soo-Jeong Cho , Chin Hur

Objective

In this commentary, we examine whether kimchi acts primarily as a risk factor or a protective dietary component for gastric cancer.

Methods

By breaking kimchi down into individual ingredients, we summarize evidence on the potential protective and carcinogenic effects.

Results

Epidemiologic findings on kimchi and gastric cancer remain inconsistent, likely due to variation in sodium content, fermentation practices, and overall dietary patterns.

Conclusions

We propose that reducing sodium content while preserving traditional fermentation methods may enhance the health benefits of kimchi while lowering preventable cancer risk. This commentary highlights the importance of culturally informed dietary strategies for gastric cancer prevention.
目的在这篇评论中,我们研究泡菜主要是作为胃癌的危险因素还是保护性饮食成分。方法将泡菜分解成不同的成分,总结其潜在的保护和致癌作用的证据。结果泡菜和胃癌的流行病学调查结果仍然不一致,可能是由于钠含量、发酵方法和整体饮食模式的差异。结论在保留传统发酵方法的同时减少泡菜的钠含量可能会增加泡菜的健康益处,同时降低可预防的癌症风险。这篇评论强调了文化知情的饮食策略对胃癌预防的重要性。
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引用次数: 0
Vaccine delay in routine childhood vaccines in the post-COVID-19 era in Jiangning, Nanjing, China 中国南京江宁地区后covid -19时代儿童常规疫苗接种延迟
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.pmedr.2025.103368
Dan Guo , Jiazhen Dai , Tiantian Zhang

Objective

There is evidence indicating that the routine childhood vaccines rate has decreased during the COVID-19 pandemic. This study aims to investigate the status of routine childhood vaccinations in the post-pandemic era and assess whether it has reverted to pre-pandemic levels.

Methods

We collected children born between January 1, 2013 and November 30, 2024 who were vaccinated in the vaccination clinic of Nanjing Jiangning Hospital. We conducted an analysis of the delayed vaccination situation during this period, compared the differences across the three phases-the pre-COVID-19 era, the COVID-19 era, the post-COVID-19 era-and examined the temporal changing trends following the epidemic.

Results

Compared to the pre-epidemic period, most routine childhood vaccinations delayed both during and after the epidemic period. In the post-pandemic phase, many vaccines (Bacillus Calmette-Guérin, Poliomyelitis vaccine3, Diphtheria, Tetanus and Acellular Pertussis Combined Vaccine3, Diphtheria, and Tetanus Combined Vaccine, Measles-containing vaccine1–2, Live attenuated Japanese Encephalitis Vaccine1–2, Group AC meningitis polysaccharide vaccine2) were administered even later than during the epidemic, and there were no signs of improvement over time.

Conclusions

Delays in routine vaccination of children persist after the pandemic, possibly due to a lack of confidence in the vaccine. More effective measures are needed to improve this worrying situation.
目的有证据表明,在COVID-19大流行期间,儿童常规疫苗接种率有所下降。本研究旨在调查大流行后时期儿童常规疫苗接种的状况,并评估其是否已恢复到大流行前的水平。方法收集2013年1月1日至2024年11月30日在南京市江宁医院预防接种门诊接种的儿童。我们分析了这一时期的延迟疫苗接种情况,比较了疫情前、疫情后三个阶段的差异,并考察了疫情发生后的时间变化趋势。结果与流行前相比,大多数儿童常规疫苗接种在流行期间和流行后延迟。在大流行后阶段,许多疫苗(卡介苗-谷氨酰胺、脊髓灰质炎疫苗3、白喉、破伤风和无细胞百日咳联合疫苗3、白喉和破伤风联合疫苗、含麻疹疫苗1 - 2、减毒日本脑炎疫苗1 - 2、AC组脑膜炎多糖疫苗2)接种时间甚至晚于大流行期间,并且随着时间的推移没有改善的迹象。结论:大流行后,儿童常规疫苗接种的延迟可能是由于对疫苗缺乏信心所致。需要采取更有效的措施来改善这种令人担忧的状况。
{"title":"Vaccine delay in routine childhood vaccines in the post-COVID-19 era in Jiangning, Nanjing, China","authors":"Dan Guo ,&nbsp;Jiazhen Dai ,&nbsp;Tiantian Zhang","doi":"10.1016/j.pmedr.2025.103368","DOIUrl":"10.1016/j.pmedr.2025.103368","url":null,"abstract":"<div><h3>Objective</h3><div>There is evidence indicating that the routine childhood vaccines rate has decreased during the COVID-19 pandemic. This study aims to investigate the status of routine childhood vaccinations in the post-pandemic era and assess whether it has reverted to pre-pandemic levels.</div></div><div><h3>Methods</h3><div>We collected children born between January 1, 2013 and November 30, 2024 who were vaccinated in the vaccination clinic of Nanjing Jiangning Hospital. We conducted an analysis of the delayed vaccination situation during this period, compared the differences across the three phases-the pre-COVID-19 era, the COVID-19 era, the post-COVID-19 era-and examined the temporal changing trends following the epidemic.</div></div><div><h3>Results</h3><div>Compared to the pre-epidemic period, most routine childhood vaccinations delayed both during and after the epidemic period. In the post-pandemic phase, many vaccines (Bacillus Calmette-Guérin, Poliomyelitis vaccine3, Diphtheria, Tetanus and Acellular Pertussis Combined Vaccine3, Diphtheria, and Tetanus Combined Vaccine, Measles-containing vaccine1–2, Live attenuated Japanese Encephalitis Vaccine1–2, Group AC meningitis polysaccharide vaccine2) were administered even later than during the epidemic, and there were no signs of improvement over time.</div></div><div><h3>Conclusions</h3><div>Delays in routine vaccination of children persist after the pandemic, possibly due to a lack of confidence in the vaccine. More effective measures are needed to improve this worrying situation.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"61 ","pages":"Article 103368"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145925814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adherence to the Mediterranean Diet, emotional well-being and lifestyle patterns in Spain: A cross-sectional study 在西班牙坚持地中海饮食、情绪健康和生活方式:一项横断面研究
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.pmedr.2026.103374
Kora-Mareen Bühler , Javier Calleja-Conde , Carlo Bressa , Félix Gómez-Gallego , Jacobo Albert , Mateo Pérez-Wiesner , Jose Antonio López-Moreno

Objectives

This study examined whether adherence to the Mediterranean Diet (MedDiet) is associated with emotional states, lifestyle behaviors, and subjective well-being in Spanish adults.

Methods

We conducted a cross-sectional survey in Spain between July and October 2023 of 2751 adults across 14 major cities. Participants completed digital questionnaires on weekly frequency of six basic emotions, anxiety, life satisfaction, happiness, and health behaviors. MedDiet adherence was assessed via a weighted 15-item score and categorized into tertiles. Associations were examined using multivariate, covariate-adjusted models.

Results

Higher MedDiet adherence was significantly associated with greater joy and surprise, and lower anger, disgust, and sadness (all p < 0.05). Participants in the highest tertile reported more frequent sport (p < 0.01), cooking, and social activities, along with higher life satisfaction and happiness (p < 0.01). Beer and wine showed distinct patterns: beer was linked to greater anger, whereas wine related to more sport and reduced anxiety.

Conclusions

MedDiet adherence reflects a lifestyle characterized by emotional balance and well-being, with distinct psychosocial patterns for wine and beer.
目的:本研究考察了西班牙成年人坚持地中海饮食(MedDiet)是否与情绪状态、生活方式行为和主观幸福感有关。方法:我们于2023年7月至10月在西班牙对14个主要城市的2751名成年人进行了横断面调查。参与者完成了关于六种基本情绪、焦虑、生活满意度、幸福感和健康行为的每周频率的数字问卷。MedDiet的依从性通过加权15项评分进行评估,并按等级进行分类。使用多变量协变量调整模型检验相关性。结果较高的MedDiet依从性与较高的喜悦和惊喜,较低的愤怒,厌恶和悲伤显著相关(p < 0.05)。得分最高的参与者报告说,他们更频繁地运动(p < 0.01)、烹饪和社交活动,同时生活满意度和幸福感也更高(p < 0.01)。啤酒和葡萄酒表现出不同的模式:啤酒与更大的愤怒有关,而葡萄酒与更多的运动和减少焦虑有关。结论坚持meddiet反映了一种以情绪平衡和健康为特征的生活方式,对葡萄酒和啤酒有不同的心理社会模式。
{"title":"Adherence to the Mediterranean Diet, emotional well-being and lifestyle patterns in Spain: A cross-sectional study","authors":"Kora-Mareen Bühler ,&nbsp;Javier Calleja-Conde ,&nbsp;Carlo Bressa ,&nbsp;Félix Gómez-Gallego ,&nbsp;Jacobo Albert ,&nbsp;Mateo Pérez-Wiesner ,&nbsp;Jose Antonio López-Moreno","doi":"10.1016/j.pmedr.2026.103374","DOIUrl":"10.1016/j.pmedr.2026.103374","url":null,"abstract":"<div><h3>Objectives</h3><div>This study examined whether adherence to the Mediterranean Diet (MedDiet) is associated with emotional states, lifestyle behaviors, and subjective well-being in Spanish adults.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional survey in Spain between July and October 2023 of 2751 adults across 14 major cities. Participants completed digital questionnaires on weekly frequency of six basic emotions, anxiety, life satisfaction, happiness, and health behaviors. MedDiet adherence was assessed via a weighted 15-item score and categorized into tertiles. Associations were examined using multivariate, covariate-adjusted models.</div></div><div><h3>Results</h3><div>Higher MedDiet adherence was significantly associated with greater joy and surprise, and lower anger, disgust, and sadness (all <em>p</em> &lt; 0.05). Participants in the highest tertile reported more frequent sport (<em>p</em> &lt; 0.01), cooking, and social activities, along with higher life satisfaction and happiness (p &lt; 0.01). Beer and wine showed distinct patterns: beer was linked to greater anger, whereas wine related to more sport and reduced anxiety.</div></div><div><h3>Conclusions</h3><div>MedDiet adherence reflects a lifestyle characterized by emotional balance and well-being, with distinct psychosocial patterns for wine and beer.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"61 ","pages":"Article 103374"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145925817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between metabolic obesity phenotypes and risk of colorectal neoplasia in a south Australian surveillance colonoscopy population 在南澳大利亚监测结肠镜人群中,代谢性肥胖表型与结直肠癌风险之间的关系
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.pmedr.2025.103360
Meseret Derbew Molla , Erin L. Symonds , Jean M. Winter , Charles Cock , Molla M. Wassie

Objective

To assess association between metabolic obesity phenotypes and risk of colorectal neoplasia in a South Australian surveillance colonoscopy population.

Methods

A retrospective cohort study in individuals undergoing surveillance colonoscopy between February 24, 2021, to May 25, 2024, was conducted. The four groups based on obesity and metabolic health status were: metabolically healthy non-obesity (MHNO) or obesity (MHO) and metabolically unhealthy non-obesity (MUNO) or obesity (MUO). Metabolically unhealthy status based on the presence of type 2 diabetes, hypertension, or dyslipidemia) and colonoscopy outcomes were collected from clinical databases. Multivariable logistic regression was applied in the overall as well as subgroup analysis by sex of participants.

Results

Both MHO (adjusted odds ratio (AOR) = 1.36, 95 % CI 1.00, 1.85) and MUO (AOR = 1.39, 95 % CI 1.11,1.76) were positively associated with the risk of conventional adenoma but not with serrated polyps as compared to non-neoplastic groups. An increased risk of advanced conventional adenoma was observed in individuals with MHO (AOR = 1.38, 95 % CI 1.04, 1.83) and MUO (AOR = 1.27, 95 % CI 1.03,1.58). This risk for advanced conventional adenomas was significant in male participants, but not in females.

Conclusions

Obesity, independent of other metabolic diseases, was associated with a higher risk of conventional adenoma, particularly in males.
目的评估南澳大利亚监测结肠镜人群中代谢性肥胖表型与结直肠瘤变风险之间的关系。方法对2021年2月24日至2024年5月25日接受结肠镜检查的患者进行回顾性队列研究。根据肥胖和代谢健康状况分为代谢健康非肥胖(MHNO)或肥胖(MHO)组和代谢不健康非肥胖(MUNO)或肥胖(MUO)组。代谢不健康状态(基于2型糖尿病、高血压或血脂异常)和结肠镜检查结果从临床数据库中收集。多变量逻辑回归应用于参与者性别的整体和亚组分析。结果与非肿瘤组相比,MHO(调整优势比(AOR) = 1.36, 95% CI 1.00, 1.85)和MUO (AOR = 1.39, 95% CI 1.11,1.76)与常规腺瘤的风险呈正相关,但与锯齿状息肉的风险无关。MHO (AOR = 1.38, 95% CI 1.04, 1.83)和MUO (AOR = 1.27, 95% CI 1.03,1.58)患者发生晚期常规腺瘤的风险增加。晚期常规腺瘤的风险在男性参与者中显著,但在女性中不显著。结论肥胖与其他代谢性疾病无关,与常规腺瘤的高风险相关,尤其是男性。
{"title":"Association between metabolic obesity phenotypes and risk of colorectal neoplasia in a south Australian surveillance colonoscopy population","authors":"Meseret Derbew Molla ,&nbsp;Erin L. Symonds ,&nbsp;Jean M. Winter ,&nbsp;Charles Cock ,&nbsp;Molla M. Wassie","doi":"10.1016/j.pmedr.2025.103360","DOIUrl":"10.1016/j.pmedr.2025.103360","url":null,"abstract":"<div><h3>Objective</h3><div>To assess association between metabolic obesity phenotypes and risk of colorectal neoplasia in a South Australian surveillance colonoscopy population.</div></div><div><h3>Methods</h3><div>A retrospective cohort study in individuals undergoing surveillance colonoscopy between February 24, 2021, to May 25, 2024, was conducted. The four groups based on obesity and metabolic health status were: metabolically healthy non-obesity (MHNO) or obesity (MHO) and metabolically unhealthy non-obesity (MUNO) or obesity (MUO). Metabolically unhealthy status based on the presence of type 2 diabetes, hypertension, or dyslipidemia) and colonoscopy outcomes were collected from clinical databases. Multivariable logistic regression was applied in the overall as well as subgroup analysis by sex of participants.</div></div><div><h3>Results</h3><div>Both MHO (adjusted odds ratio (AOR) = 1.36, 95 % CI 1.00, 1.85) and MUO (AOR = 1.39, 95 % CI 1.11,1.76) were positively associated with the risk of conventional adenoma but not with serrated polyps as compared to non-neoplastic groups. An increased risk of advanced conventional adenoma was observed in individuals with MHO (AOR = 1.38, 95 % CI 1.04, 1.83) and MUO (AOR = 1.27, 95 % CI 1.03,1.58). This risk for advanced conventional adenomas was significant in male participants, but not in females.</div></div><div><h3>Conclusions</h3><div>Obesity, independent of other metabolic diseases, was associated with a higher risk of conventional adenoma, particularly in males.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"61 ","pages":"Article 103360"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145925875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Boosting psychological well-being in infertile women undergoing IVF through Fordyce happiness counseling: a quasi-experimental approach in Zahedan, Southeast Iran 通过福代斯幸福咨询提高接受体外受精的不孕妇女的心理健康:伊朗东南部扎黑丹的一种准实验方法
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.pmedr.2025.103372
Tahereh Boryri, Parisa Delghavi, Somayyeh Khazaeian

Objectives

Infertility imposes a significant psychological burden, especially for women undergoing assisted reproductive technologies(ART). This study assessed the effectiveness of Fordyce's happiness-based counseling in reducing depression, anxiety, and stress among women undergoing in vitro fertilization (IVF).

Methods

A quasi-experimental study was conducted among 60 women (30 intervention, 30 control) undergoing IVF in Zahedan, Iran, in 2024. Infertility clinics affiliated with Zahedan University of Medical Sciences were randomly selected, and eligible participants were recruited based on inclusion criteria. The intervention group received six weekly face-to-face counseling sessions based on Fordyce's happiness model. Psychological outcomes were assessed using the Depression Anxiety Stress Scale-21 (DASS-21) before and four weeks post-intervention. Data were analyzed using independent t-tests, chi-square tests, and repeated measures ANOVA.

Results

Counseling significantly reduced stress (F = 181.4, p < 0.01, partial η2 = 0.8), anxiety (F = 29.3, p < 0.01, partial η2 = 0.3), and depression (F = 125.1, p < 0.01, partial η2 = 0.8). Post-intervention mean scores in the intervention group decreased for stress (18.5 ± 2.9), anxiety (17.6 ± 2.3), and depression (21.5 ± 5.7) compared with control scores (26.6 ± 5.1; 24.8 ± 1.9; 24.8 ± 5.1).

Conclusion

Fordyce's happiness-based counseling is an effective, low-cost, culturally adaptable intervention to alleviate psychological distress in women undergoing ART. Integrating it into infertility care programs may enhance emotional well-being, particularly in resource-limited settings.
不孕不育给患者带来了巨大的心理负担,尤其是对接受辅助生殖技术(ART)治疗的女性。本研究评估了福代斯的以幸福为基础的咨询在减少体外受精(IVF)妇女的抑郁、焦虑和压力方面的有效性。方法对2024年在伊朗扎黑丹(Zahedan)接受体外受精(IVF)的60例女性(干预组30例,对照组30例)进行准实验研究。随机选择扎黑丹医科大学附属不孕不育诊所,根据纳入标准招募符合条件的受试者。干预组每周接受六次基于福代斯幸福模型的面对面咨询。在干预前和干预后四周使用抑郁焦虑压力量表-21 (DASS-21)评估心理结果。数据分析采用独立t检验、卡方检验和重复测量方差分析。结果心理咨询能显著降低压力(F = 181.4, p < 0.01,偏η2 = 0.8)、焦虑(F = 29.3, p < 0.01,偏η2 = 0.3)、抑郁(F = 125.1, p < 0.01,偏η2 = 0.8)。干预组干预后应激(18.5±2.9)、焦虑(17.6±2.3)、抑郁(21.5±5.7)得分均低于对照组(26.6±5.1;24.8±1.9;24.8±5.1)。结论福代斯幸福咨询是一种有效的、低成本的、文化适应性强的干预措施,可缓解接受抗逆转录病毒治疗妇女的心理困扰。将其纳入不孕症护理计划可能会增强情感健康,特别是在资源有限的情况下。
{"title":"Boosting psychological well-being in infertile women undergoing IVF through Fordyce happiness counseling: a quasi-experimental approach in Zahedan, Southeast Iran","authors":"Tahereh Boryri,&nbsp;Parisa Delghavi,&nbsp;Somayyeh Khazaeian","doi":"10.1016/j.pmedr.2025.103372","DOIUrl":"10.1016/j.pmedr.2025.103372","url":null,"abstract":"<div><h3>Objectives</h3><div>Infertility imposes a significant psychological burden, especially for women undergoing assisted reproductive technologies(ART). This study assessed the effectiveness of Fordyce's happiness-based counseling in reducing depression, anxiety, and stress among women undergoing in vitro fertilization (IVF).</div></div><div><h3>Methods</h3><div>A quasi-experimental study was conducted among 60 women (30 intervention, 30 control) undergoing IVF in Zahedan, Iran, in 2024. Infertility clinics affiliated with Zahedan University of Medical Sciences were randomly selected, and eligible participants were recruited based on inclusion criteria. The intervention group received six weekly face-to-face counseling sessions based on Fordyce's happiness model. Psychological outcomes were assessed using the Depression Anxiety Stress Scale-21 (DASS-21) before and four weeks post-intervention. Data were analyzed using independent <em>t</em>-tests, chi-square tests, and repeated measures ANOVA.</div></div><div><h3>Results</h3><div>Counseling significantly reduced stress (F = 181.4, <em>p</em> &lt; 0.01, partial η<sup>2</sup> = 0.8), anxiety (F = 29.3, <em>p</em> &lt; 0.01, partial η<sup>2</sup> = 0.3), and depression (F = 125.1, p &lt; 0.01, partial η<sup>2</sup> = 0.8). Post-intervention mean scores in the intervention group decreased for stress (18.5 ± 2.9), anxiety (17.6 ± 2.3), and depression (21.5 ± 5.7) compared with control scores (26.6 ± 5.1; 24.8 ± 1.9; 24.8 ± 5.1).</div></div><div><h3>Conclusion</h3><div>Fordyce's happiness-based counseling is an effective, low-cost, culturally adaptable intervention to alleviate psychological distress in women undergoing ART. Integrating it into infertility care programs may enhance emotional well-being, particularly in resource-limited settings.</div></div>","PeriodicalId":38066,"journal":{"name":"Preventive Medicine Reports","volume":"61 ","pages":"Article 103372"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145925813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Preventive Medicine Reports
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