Pub Date : 2025-12-10DOI: 10.1016/j.scog.2025.100412
Michael F. Green , Keith H. Nuechterlein
{"title":"International use of social cognition assessments: Commentary on Ziermans et al.","authors":"Michael F. Green , Keith H. Nuechterlein","doi":"10.1016/j.scog.2025.100412","DOIUrl":"10.1016/j.scog.2025.100412","url":null,"abstract":"","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"44 ","pages":"Article 100412"},"PeriodicalIF":3.0,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145705309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-10DOI: 10.1016/j.scog.2025.100414
David Dodell-Feder , Steven M. Silverstein
{"title":"Starting from scratch: Ziermans et al. commentary","authors":"David Dodell-Feder , Steven M. Silverstein","doi":"10.1016/j.scog.2025.100414","DOIUrl":"10.1016/j.scog.2025.100414","url":null,"abstract":"","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"44 ","pages":"Article 100414"},"PeriodicalIF":3.0,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145705308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-02DOI: 10.1016/j.scog.2025.100408
Wanchen Zhao , Samuel D. McDougle , Tyrone D. Cannon
Background
People higher in psychosis-proneness tend to resist belief revision despite contradictory evidence, potentially due to impaired error-monitoring. Post-error slowing (PES), one measure of error-monitoring, is linked to working memory (WM) recruitment. With limited WM capacity, psychosis-proneness could impair belief updating through poor error-monitoring during instrumental learning.
Methods
153 participants from Prolific were included in final analyses. To investigate how error-monitoring may explain impaired belief updating among those with psychosis-proneness, we implemented a Visuomotor Reinforcement Learning Task with varying WM loads, Interpretation Inflexibility Task, and Multidimensional Schizotypy Scale – Brief.
Results
Participants with higher positive schizotypy showed less PES at lower loads on the visuomotor instrumental learning task. WM capacity was associated positively with PES but negatively with positive schizotypy. Notably, it is only among participants higher in positive schizotypy that reduced PES associated with more severe belief inflexibility
Conclusions
These results suggest that impaired top-down error monitoring in psychosis-proneness may stem from WM limitations, leading to greater reliance on slower RL-based learning. This cognitive profile might prevent efficient belief adjustment and error correction, connecting executive function deficits in psychosis-proneness to performance monitoring and cognitive inflexibility.
{"title":"Psychosis-proneness is associated with reduced cognitive error-monitoring during instrumental learning","authors":"Wanchen Zhao , Samuel D. McDougle , Tyrone D. Cannon","doi":"10.1016/j.scog.2025.100408","DOIUrl":"10.1016/j.scog.2025.100408","url":null,"abstract":"<div><h3>Background</h3><div>People higher in psychosis-proneness tend to resist belief revision despite contradictory evidence, potentially due to impaired error-monitoring. Post-error slowing (PES), one measure of error-monitoring, is linked to working memory (WM) recruitment. With limited WM capacity, psychosis-proneness could impair belief updating through poor error-monitoring during instrumental learning.</div></div><div><h3>Methods</h3><div>153 participants from Prolific were included in final analyses. To investigate how error-monitoring may explain impaired belief updating among those with psychosis-proneness, we implemented a Visuomotor Reinforcement Learning Task with varying WM loads, Interpretation Inflexibility Task, and Multidimensional Schizotypy Scale – Brief.</div></div><div><h3>Results</h3><div>Participants with higher positive schizotypy showed less PES at lower loads on the visuomotor instrumental learning task. WM capacity was associated positively with PES but negatively with positive schizotypy. Notably, it is only among participants higher in positive schizotypy that reduced PES associated with more severe belief inflexibility</div></div><div><h3>Conclusions</h3><div>These results suggest that impaired top-down error monitoring in psychosis-proneness may stem from WM limitations, leading to greater reliance on slower RL-based learning. This cognitive profile might prevent efficient belief adjustment and error correction, connecting executive function deficits in psychosis-proneness to performance monitoring and cognitive inflexibility.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"43 ","pages":"Article 100408"},"PeriodicalIF":3.0,"publicationDate":"2025-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145690797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.scog.2025.100410
Steven Samuel , Markus Boeckle
Previous research has suggested that fewer schizophrenic and schizotypal traits are reported in a second language than a mother tongue. Such results make sense in the light of the so-called Foreign Language Effect (FLE), whereby bilinguals make more rational decisions and are less influenced by emotions and biases in a learned second language (L2) than a mother tongue (L1). However, this previous research is to date very limited, and apart from one large-scale quantitative study is based primarily on anecdotal evidence. In the study reported here, we gave German-English bilinguals the Schizotypal Personality Questionnaire in either English or German. If doing the questionnaire in an L2 (here English) makes participants think more rationally and less emotionally, then fewer schizotypal traits should be reported in these participants than those who answer the same questions in their L1 (German). Results failed to support this hypothesis; there was no evidence that bilinguals reported fewer traits in their second language. We interpret these data as suggesting that the link between schizotypy (specifically) and language context may be weaker or less reliable than hitherto supposed.
{"title":"No foreign language effect in Schizotypy: Evidence from German-English bilinguals","authors":"Steven Samuel , Markus Boeckle","doi":"10.1016/j.scog.2025.100410","DOIUrl":"10.1016/j.scog.2025.100410","url":null,"abstract":"<div><div>Previous research has suggested that fewer schizophrenic and schizotypal traits are reported in a second language than a mother tongue. Such results make sense in the light of the so-called Foreign Language Effect (FLE), whereby bilinguals make more rational decisions and are less influenced by emotions and biases in a learned second language (L2) than a mother tongue (L1). However, this previous research is to date very limited, and apart from one large-scale quantitative study is based primarily on anecdotal evidence. In the study reported here, we gave German-English bilinguals the Schizotypal Personality Questionnaire in either English or German. If doing the questionnaire in an L2 (here English) makes participants think more rationally and less emotionally, then fewer schizotypal traits should be reported in these participants than those who answer the same questions in their L1 (German). Results failed to support this hypothesis; there was no evidence that bilinguals reported fewer traits in their second language. We interpret these data as suggesting that the link between schizotypy (specifically) and language context may be weaker or less reliable than hitherto supposed.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"43 ","pages":"Article 100410"},"PeriodicalIF":3.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145690799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-26DOI: 10.1016/j.scog.2025.100407
Sunghye Cho , Yan Cong , Aarush Mehta , Amir H. Nikzad , Sarah A. Berretta , Leily M. Behbehani , Mark Liberman , Sunny X. Tang
Background
Verbal fluency tasks reveal consistent impairments among individuals with schizophrenia (SSD) and shed valuable insight on semantic and cognitive processing. However, comparisons with other psychiatric groups remain limited. Doing so may help clarify whether characteristics are unique to SSD versus shared across diagnoses. This study compared verbal fluency responses among participants with SSD, unipolar depression, and healthy volunteers (HV).
Methods
Participants with SSD (n = 64), unipolar depression (n = 70), and HVs (n = 37) completed letter- and category-guided verbal fluency tasks. Using automated pipelines, we extracted total correct responses, pause durations, first response latency, semantic and phonemic distances, and the number and size of semantic/phonemic clusters. Associations between fluency metrics and clinical ratings of speech disturbances (e.g., incoherence, inefficiency) were examined within patient groups.
Results
Groups differed significantly in total fluency scores, particularly on the category fluency task, with the greatest impairment in SSD and intermediate effects in depression. Significant pairwise group differences emerged in the number of semantic and phonemic clusters in the category task, while cluster size showed fewer differences. In HVs, both semantic and phonemic distances increased with longer pauses, suggesting strategic cluster switching. This pattern was absent in SSD and depression groups. SSD exhibited longer first latency and pauses relative to HVs; participants with depression showed no change in latency, but similarly prolonged pauses.
Conclusion
Individuals with SSD and depression exhibit distinct patterns in verbal fluency, with category tasks revealing more robust group differences. Automated fluency analysis offers a scalable approach for differentially detecting cognitive-linguistic impairments across psychiatric populations.
{"title":"Unique signatures in verbal fluency task performance in schizophrenia and depression","authors":"Sunghye Cho , Yan Cong , Aarush Mehta , Amir H. Nikzad , Sarah A. Berretta , Leily M. Behbehani , Mark Liberman , Sunny X. Tang","doi":"10.1016/j.scog.2025.100407","DOIUrl":"10.1016/j.scog.2025.100407","url":null,"abstract":"<div><h3>Background</h3><div>Verbal fluency tasks reveal consistent impairments among individuals with schizophrenia (SSD) and shed valuable insight on semantic and cognitive processing. However, comparisons with other psychiatric groups remain limited. Doing so may help clarify whether characteristics are unique to SSD versus shared across diagnoses. This study compared verbal fluency responses among participants with SSD, unipolar depression, and healthy volunteers (HV).</div></div><div><h3>Methods</h3><div>Participants with SSD (<em>n</em> = 64), unipolar depression (<em>n</em> = 70), and HVs (<em>n</em> = 37) completed letter- and category-guided verbal fluency tasks. Using automated pipelines, we extracted total correct responses, pause durations, first response latency, semantic and phonemic distances, and the number and size of semantic/phonemic clusters. Associations between fluency metrics and clinical ratings of speech disturbances (e.g., incoherence, inefficiency) were examined within patient groups.</div></div><div><h3>Results</h3><div>Groups differed significantly in total fluency scores, particularly on the category fluency task, with the greatest impairment in SSD and intermediate effects in depression. Significant pairwise group differences emerged in the number of semantic and phonemic clusters in the category task, while cluster size showed fewer differences. In HVs, both semantic and phonemic distances increased with longer pauses, suggesting strategic cluster switching. This pattern was absent in SSD and depression groups. SSD exhibited longer first latency and pauses relative to HVs; participants with depression showed no change in latency, but similarly prolonged pauses.</div></div><div><h3>Conclusion</h3><div>Individuals with SSD and depression exhibit distinct patterns in verbal fluency, with category tasks revealing more robust group differences. Automated fluency analysis offers a scalable approach for differentially detecting cognitive-linguistic impairments across psychiatric populations.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"43 ","pages":"Article 100407"},"PeriodicalIF":3.0,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145623532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-18DOI: 10.1016/j.scog.2025.100400
T.B. Ziermans , M. Hajdúk , A.E. Pinkham , SIRS Social Cognition Research Harmonization Group
Objective
To describe current practices and key barriers in social cognition (SC) assessment, given its central role in psychiatric and neurological disorders and the limitations of existing measures.
Methods
Fifty-two SC experts from 20 countries completed an online survey regarding SC tests and questions about their usage frequency and perceived obstacles.
Results
Only facial emotion recognition tasks were used frequently, while the Hinting task and Reading the Mind in the Eyes Test (RMET) were used by over half of participants. However, 10 experts also urged discontinuation of RMET, mostly due to validity concerns. Major obstacles included lack of culture-appropriate norms and poor psychometric properties.
Conclusions
SC assessment is limited by cultural bias and weak psychometrics. Developing and validating culturally sensitive tools, harmonizing protocols, and securing funding are essential to advance research, enable international trials, and improve clinical outcomes.
{"title":"Call to action on social cognition measures in clinical research","authors":"T.B. Ziermans , M. Hajdúk , A.E. Pinkham , SIRS Social Cognition Research Harmonization Group","doi":"10.1016/j.scog.2025.100400","DOIUrl":"10.1016/j.scog.2025.100400","url":null,"abstract":"<div><h3>Objective</h3><div>To describe current practices and key barriers in social cognition (SC) assessment, given its central role in psychiatric and neurological disorders and the limitations of existing measures.</div></div><div><h3>Methods</h3><div>Fifty-two SC experts from 20 countries completed an online survey regarding SC tests and questions about their usage frequency and perceived obstacles.</div></div><div><h3>Results</h3><div>Only facial emotion recognition tasks were used frequently, while the Hinting task and Reading the Mind in the Eyes Test (RMET) were used by over half of participants. However, 10 experts also urged discontinuation of RMET, mostly due to validity concerns. Major obstacles included lack of culture-appropriate norms and poor psychometric properties.</div></div><div><h3>Conclusions</h3><div>SC assessment is limited by cultural bias and weak psychometrics. Developing and validating culturally sensitive tools, harmonizing protocols, and securing funding are essential to advance research, enable international trials, and improve clinical outcomes.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"43 ","pages":"Article 100400"},"PeriodicalIF":3.0,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-15DOI: 10.1016/j.scog.2025.100405
Francesca Happé
{"title":"Commentary on Ziermans, Hajdúk, Pinkham, et al.'s “Call to Action on Social Cognition Measures in Clinical Research”","authors":"Francesca Happé","doi":"10.1016/j.scog.2025.100405","DOIUrl":"10.1016/j.scog.2025.100405","url":null,"abstract":"","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"43 ","pages":"Article 100405"},"PeriodicalIF":3.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1016/j.scog.2025.100406
Stephanie H. Read , Artak Khachatryan , Theresa A. Cassidy
Background
Cognitive impairment is a core feature of schizophrenia that can reduce functional capacity and quality of life in patients. However, it is unclear how physicians approach cognitive impairment associated with schizophrenia (CIAS) in real-world clinical practice. This study examines the knowledge, attitudes and practices of psychiatrists towards CIAS in patients.
Methods
This non-interventional, cross-sectional study sampled psychiatrists across the US, UK and Germany with ≥36 months of clinical experience and who treated ≥5 patients with schizophrenia annually. Psychiatrists completed an online survey in December 2022 assessing their knowledge, attitudes and practices towards cognitive impairment in patients with schizophrenia. Outcome variables were analysed descriptively (patient estimates: median [IQR]; psychiatrist characteristics: n [%]).
Results
Overall, 121 eligible psychiatrists completed the survey. Psychiatrists estimated that 50.0 % (28.0;80.0) of patients with schizophrenia exhibited cognitive impairment and diagnosed CIAS in 25.0 % (10.0;50.0) of patients. CIAS symptoms reportedly worsened over time and were transient in 50.0 % (30.0;70.0) and 20.0 % (10.0;30.0) of patients, respectively. Working and studying were ranked the activities of daily living most disrupted by CIAS by 48.8 % (n = 59) of psychiatrists. Only 18.2 % (n = 22) of psychiatrists were aware of effective CIAS treatments and 59.5 % (n = 72) did not administer medication for CIAS. Psychiatrists employed a watch-and-wait strategy in 50.0 % (20.0;70.0) of patients with CIAS.
Conclusions
This study demonstrates limited consensus among psychiatrists regarding CIAS characterisation, diagnosis and management. These insights highlight an unmet need for effective diagnosis and treatment of CIAS, necessitating further research to improve the evidence base for clinical guidelines informing CIAS management.
{"title":"Diagnosis and management of cognitive impairment associated with schizophrenia: Real-world evidence from a cross-sectional survey of psychiatrists","authors":"Stephanie H. Read , Artak Khachatryan , Theresa A. Cassidy","doi":"10.1016/j.scog.2025.100406","DOIUrl":"10.1016/j.scog.2025.100406","url":null,"abstract":"<div><h3>Background</h3><div>Cognitive impairment is a core feature of schizophrenia that can reduce functional capacity and quality of life in patients. However, it is unclear how physicians approach cognitive impairment associated with schizophrenia (CIAS) in real-world clinical practice. This study examines the knowledge, attitudes and practices of psychiatrists towards CIAS in patients.</div></div><div><h3>Methods</h3><div>This non-interventional, cross-sectional study sampled psychiatrists across the US, UK and Germany with ≥36 months of clinical experience and who treated ≥5 patients with schizophrenia annually. Psychiatrists completed an online survey in December 2022 assessing their knowledge, attitudes and practices towards cognitive impairment in patients with schizophrenia. Outcome variables were analysed descriptively (patient estimates: median [IQR]; psychiatrist characteristics: n [%]).</div></div><div><h3>Results</h3><div>Overall, 121 eligible psychiatrists completed the survey. Psychiatrists estimated that 50.0 % (28.0;80.0) of patients with schizophrenia exhibited cognitive impairment and diagnosed CIAS in 25.0 % (10.0;50.0) of patients. CIAS symptoms reportedly worsened over time and were transient in 50.0 % (30.0;70.0) and 20.0 % (10.0;30.0) of patients, respectively. Working and studying were ranked the activities of daily living most disrupted by CIAS by 48.8 % (<em>n</em> = 59) of psychiatrists. Only 18.2 % (<em>n</em> = 22) of psychiatrists were aware of effective CIAS treatments and 59.5 % (<em>n</em> = 72) did not administer medication for CIAS. Psychiatrists employed a watch-and-wait strategy in 50.0 % (20.0;70.0) of patients with CIAS.</div></div><div><h3>Conclusions</h3><div>This study demonstrates limited consensus among psychiatrists regarding CIAS characterisation, diagnosis and management. These insights highlight an unmet need for effective diagnosis and treatment of CIAS, necessitating further research to improve the evidence base for clinical guidelines informing CIAS management.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"43 ","pages":"Article 100406"},"PeriodicalIF":3.0,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
It is estimated that approximately 40 % of individuals diagnosed with schizophrenia also meet the diagnostic criteria for a personality disorder. This comorbidity is associated with an unfavorable prognosis for the illness. Given that cognition is currently the best predictor of recovery, this study aims to characterize the cognitive profiles of individuals with comorbid personality disorders and schizophrenia by reviewing literature from the past 24 years. We sought to determine whether the cognitive deficits differed from that of individuals with only a schizophrenia diagnosis, and to further characterize these differences.
Method
Articles were gathered from PubMed, Google Scholar, Web of Science, PsychInfo, PsychNet, MedLine, and EMBASE. They were selected based on the following inclusion criteria: (a) use of neuropsychological or social cognition measures, (b) explicit mental disorder diagnosis established using validated diagnostic tools, (c) participants with a comorbid personality disorder and schizophrenia diagnosis, and (d) results of neuropsychological measures specific to participants with this type of comorbidity.
Results
A total of 10 articles were included. Of these, six clinically established a personality disorder diagnosis, while five measured traits associated with various personality disorders. Due to the heterogeneity of methodologies across the studies, no statistical conclusions could be drawn.
Discussion/conclusion
Our review did highlight a greater presence of studies on antisocial personality, with few on other personality disorders or traits. Given the high comorbidity of personality disorders in schizophrenia, and the important impact of cognition on functioning, including social cognition, more studies are warranted. Recommendations for both clinicians and researchers are proposed.
目的据估计，大约40%的精神分裂症患者同时符合人格障碍的诊断标准。这种合并症与疾病的不良预后有关。鉴于认知是目前康复的最佳预测指标，本研究旨在通过回顾过去24年的文献来描述患有共病人格障碍和精神分裂症的个体的认知特征。我们试图确定认知缺陷是否与仅诊断为精神分裂症的个体不同，并进一步表征这些差异。方法论文收集自PubMed、谷歌Scholar、Web of Science、PsychInfo、PsychNet、MedLine和EMBASE。他们的选择基于以下纳入标准：(a)使用神经心理学或社会认知测量，(b)使用经过验证的诊断工具建立明确的精神障碍诊断，(c)患有共病人格障碍和精神分裂症诊断的参与者，以及(d)针对患有这种共病的参与者的神经心理学测量结果。结果共纳入10篇文献。其中，6项临床诊断确定了人格障碍，5项测量了与各种人格障碍相关的特征。由于研究方法的异质性，无法得出统计结论。讨论/结论：我们的综述确实强调了反社会人格的研究较多，而其他人格障碍或特征的研究较少。鉴于精神分裂症中人格障碍的高合并症，以及认知对功能（包括社会认知）的重要影响，需要进行更多的研究。对临床医生和研究人员提出了建议。
{"title":"Cognitive deficits in individuals with comorbid personality disorder and schizophrenia: A scoping review","authors":"Anouck Chalut , Stéphane Potvin , Laura Iozzino , Marie-Ange Binette , Hubert Fiset-Renaud , Sara Abou Chabake , Tania Lecomte","doi":"10.1016/j.scog.2025.100403","DOIUrl":"10.1016/j.scog.2025.100403","url":null,"abstract":"<div><h3>Objective</h3><div>It is estimated that approximately 40 % of individuals diagnosed with schizophrenia also meet the diagnostic criteria for a personality disorder. This comorbidity is associated with an unfavorable prognosis for the illness. Given that cognition is currently the best predictor of recovery, this study aims to characterize the cognitive profiles of individuals with comorbid personality disorders and schizophrenia by reviewing literature from the past 24 years. We sought to determine whether the cognitive deficits differed from that of individuals with only a schizophrenia diagnosis, and to further characterize these differences.</div></div><div><h3>Method</h3><div>Articles were gathered from PubMed, Google Scholar, Web of Science, PsychInfo, PsychNet, MedLine, and EMBASE. They were selected based on the following inclusion criteria: (a) use of neuropsychological or social cognition measures, (b) explicit mental disorder diagnosis established using validated diagnostic tools, (c) participants with a comorbid personality disorder and schizophrenia diagnosis, and (d) results of neuropsychological measures specific to participants with this type of comorbidity.</div></div><div><h3>Results</h3><div>A total of 10 articles were included. Of these, six clinically established a personality disorder diagnosis, while five measured traits associated with various personality disorders. Due to the heterogeneity of methodologies across the studies, no statistical conclusions could be drawn.</div></div><div><h3>Discussion/conclusion</h3><div>Our review did highlight a greater presence of studies on antisocial personality, with few on other personality disorders or traits. Given the high comorbidity of personality disorders in schizophrenia, and the important impact of cognition on functioning, including social cognition, more studies are warranted. Recommendations for both clinicians and researchers are proposed.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"43 ","pages":"Article 100403"},"PeriodicalIF":3.0,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145474355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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