Pub Date : 2025-01-01DOI: 10.1016/j.eucr.2024.102916
Meghana Singh , Michael Raver , Bianca DeAgresta , Alexandra Della Pia , Sonam Saxena , Merieme Klobocista , Nitin Yerram
Primary clear cell adenocarcinoma (CCA) of the urinary bladder is a rare and aggressive malignancy. Few reports in the literature describe this presentation, as associated with malignant transformation of endometriosis. This case highlights the complex etiology of this variant of CCA, initially diagnosed using comprehensive imaging and genetic analysis, and subsequently confirmed through extensive surgical intervention and chemotherapy.
{"title":"Endometriosis-associated primary clear cell adenocarcinoma of the urinary bladder: A case report and literature review","authors":"Meghana Singh , Michael Raver , Bianca DeAgresta , Alexandra Della Pia , Sonam Saxena , Merieme Klobocista , Nitin Yerram","doi":"10.1016/j.eucr.2024.102916","DOIUrl":"10.1016/j.eucr.2024.102916","url":null,"abstract":"<div><div>Primary clear cell adenocarcinoma (CCA) of the urinary bladder is a rare and aggressive malignancy. Few reports in the literature describe this presentation, as associated with malignant transformation of endometriosis. This case highlights the complex etiology of this variant of CCA, initially diagnosed using comprehensive imaging and genetic analysis, and subsequently confirmed through extensive surgical intervention and chemotherapy.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"58 ","pages":"Article 102916"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.eucr.2024.102910
Abdirahman Burale , Elias Sertse , Solomon Bishaw , Ferid A. Abubeker , Musse Ahmed , Samatar Abshir Mohamed , Hassan Sh Abdirahman Elmi
Blunt trauma is a common cause of renal injuries, usually managed conservatively unless there's hemodynamic instability, which warrants surgery. We present a case of a 22-year-old male with isolated Grade 5 renal injury, diagnosed via CT scan after blunt trauma. Despite the severity, he was successfully treated without surgery through conservative management in the ICU, with frequent monitoring and stabilization of his condition. While the best approach for hemodynamically stable Grade 5 renal injuries remains debated, our case suggests that conservative management is a viable option when patients are carefully monitored for any signs of instability.
{"title":"Conservative management of grade 5 renal injury: Case report","authors":"Abdirahman Burale , Elias Sertse , Solomon Bishaw , Ferid A. Abubeker , Musse Ahmed , Samatar Abshir Mohamed , Hassan Sh Abdirahman Elmi","doi":"10.1016/j.eucr.2024.102910","DOIUrl":"10.1016/j.eucr.2024.102910","url":null,"abstract":"<div><div>Blunt trauma is a common cause of renal injuries, usually managed conservatively unless there's hemodynamic instability, which warrants surgery. We present a case of a 22-year-old male with isolated Grade 5 renal injury, diagnosed via CT scan after blunt trauma. Despite the severity, he was successfully treated without surgery through conservative management in the ICU, with frequent monitoring and stabilization of his condition. While the best approach for hemodynamically stable Grade 5 renal injuries remains debated, our case suggests that conservative management is a viable option when patients are carefully monitored for any signs of instability.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"58 ","pages":"Article 102910"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11721801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.eucr.2024.102909
Viktoriya Boncheva, Omid Yassaie, Andrew Kennedy-Smith
Primary malignant mucosal melanoma of the female urethra is extremely rare and associated with high recurrence rates and exceptionally poor 5-year survival. Due to its rarity, treatment strategies are heterogenous and often extrapolated from the treatment of other more common types of melanomas. Herein, we describe a case of malignant melanoma of the urethra in a Caucasian female.
{"title":"Primary malignant melanoma of the female urethra: A case report","authors":"Viktoriya Boncheva, Omid Yassaie, Andrew Kennedy-Smith","doi":"10.1016/j.eucr.2024.102909","DOIUrl":"10.1016/j.eucr.2024.102909","url":null,"abstract":"<div><div>Primary malignant mucosal melanoma of the female urethra is extremely rare and associated with high recurrence rates and exceptionally poor 5-year survival. Due to its rarity, treatment strategies are heterogenous and often extrapolated from the treatment of other more common types of melanomas. Herein, we describe a case of malignant melanoma of the urethra in a Caucasian female.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"58 ","pages":"Article 102909"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11721210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.eucr.2024.102899
M. Vukovic, M. Albijanic, N. Radovic
We present a case of a 66-year-old man with a three-year history of Gleason 10 prostate cancer (PCa), who presented with penile pain, erythema, and induration of the penile shaft. His cancer was treated with androgen deprivation therapy (ADT), radiotherapy, and apalutamide, resulting in PSA reduction; however, a solitary penile lesion persisted, necessitating radical penectomy. At 12 months post-surgery, PSA levels and magnetic resonance imaging findings remained stable, with no signs of metastasis. This case highlights the viability of radical penectomy for solitary penile metastasis in hormone-sensitive metastatic prostate cancer (mHSPC), with potential benefits for symptom control and survival.
{"title":"Total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer (mHSPC): Case report with surgical technique","authors":"M. Vukovic, M. Albijanic, N. Radovic","doi":"10.1016/j.eucr.2024.102899","DOIUrl":"10.1016/j.eucr.2024.102899","url":null,"abstract":"<div><div>We present a case of a 66-year-old man with a three-year history of Gleason 10 prostate cancer (PCa), who presented with penile pain, erythema, and induration of the penile shaft. His cancer was treated with androgen deprivation therapy (ADT), radiotherapy, and apalutamide, resulting in PSA reduction; however, a solitary penile lesion persisted, necessitating radical penectomy. At 12 months post-surgery, PSA levels and magnetic resonance imaging findings remained stable, with no signs of metastasis. This case highlights the viability of radical penectomy for solitary penile metastasis in hormone-sensitive metastatic prostate cancer (mHSPC), with potential benefits for symptom control and survival.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"58 ","pages":"Article 102899"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11681895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.eucr.2024.102904
Yuzhi Wan, Feng Xiao, Jiang Wu, Chaowu Chen
We report a rare case of nephrocolic fistula in a 56-year-old female presenting with a three-month history of altered bowel habits. Initial colonoscopy revealed a sinus tract in the descending colon. Her hemoglobin was 79 g/L, and she had a history of nephrolithiasis and trauma. Further imaging, including CT and contrast studies, confirmed a nephrocolic fistula. Surgical intervention involved left hemicolectomy, excision of the fistula tract, and renal repair. This case highlights the importance of considering nephrocolic fistula in patients with gastrointestinal symptoms and a history of urinary tract pathology.
{"title":"A case of nephrocolic fistula presenting primarily with changes in bowel habits","authors":"Yuzhi Wan, Feng Xiao, Jiang Wu, Chaowu Chen","doi":"10.1016/j.eucr.2024.102904","DOIUrl":"10.1016/j.eucr.2024.102904","url":null,"abstract":"<div><div>We report a rare case of nephrocolic fistula in a 56-year-old female presenting with a three-month history of altered bowel habits. Initial colonoscopy revealed a sinus tract in the descending colon. Her hemoglobin was 79 g/L, and she had a history of nephrolithiasis and trauma. Further imaging, including CT and contrast studies, confirmed a nephrocolic fistula. Surgical intervention involved left hemicolectomy, excision of the fistula tract, and renal repair. This case highlights the importance of considering nephrocolic fistula in patients with gastrointestinal symptoms and a history of urinary tract pathology.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"58 ","pages":"Article 102904"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11696616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.eucr.2024.102913
EL Abidi Hamza , Ibrahimi Ahmed , Tariqi Reda , Mikou Mohammed Ali , Bennasser Abdallah , EL Sayegh Hashem , Nouini Yassine
Fournier's gangrene is a grave necrotizing fasciitis that primarily affects the perineum, spreading through the fascias and leading to significant tissue destruction. The involvement of the urethra in necrosis is extremely rare, if not anecdotal.
Emphysematous pyelonephritis, is a urinary infection with a high risk of progression to sepsis. Although both Fournier's gangrene and obstructive pyelonephritis are independently well-documented, their concurrent presentation is uncommon and poses significant diagnostic and therapeutic challenges.
In this report, we present a rare case of Fournier's gangrene secondary to emphysematous pyelonephritis, which further led to necrosis of the corpus spongiosum, a scarcely reported complication.
{"title":"Fournier's gangrene with corpus spongiosum necrosis following obstructive emphysematous pyelonephritis: An exceptional and severe urological complication","authors":"EL Abidi Hamza , Ibrahimi Ahmed , Tariqi Reda , Mikou Mohammed Ali , Bennasser Abdallah , EL Sayegh Hashem , Nouini Yassine","doi":"10.1016/j.eucr.2024.102913","DOIUrl":"10.1016/j.eucr.2024.102913","url":null,"abstract":"<div><div>Fournier's gangrene is a grave necrotizing fasciitis that primarily affects the perineum, spreading through the fascias and leading to significant tissue destruction. The involvement of the urethra in necrosis is extremely rare, if not anecdotal.</div><div>Emphysematous pyelonephritis, is a urinary infection with a high risk of progression to sepsis. Although both Fournier's gangrene and obstructive pyelonephritis are independently well-documented, their concurrent presentation is uncommon and poses significant diagnostic and therapeutic challenges.</div><div>In this report, we present a rare case of Fournier's gangrene secondary to emphysematous pyelonephritis, which further led to necrosis of the corpus spongiosum, a scarcely reported complication.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"58 ","pages":"Article 102913"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blastomycosis dermatitidis is a fungal pathogen endemic to North America. Infection from inhalation of its conidia has diffuse clinical manifestations. These can include genitourinary system infections which may manifest as ulcerative, draining skin lesions. Tissue culture is essential as anerobic bacteria and fungi grow more reliably through this medium, than with tissue swabs. A more accurate and efficient diagnosis of blastomycosis, as evidenced in this case, would have prevented prolonged treatment for presumed bacterial epididymo-orchitis and would have eliminated concern regarding possible disseminated malignancy.
{"title":"Blastomycosis of the scrotum: Not a fun guy","authors":"Duncan Petrik , Dylan Hoare , Megan MacGillivray , Daniel Ricciuto","doi":"10.1016/j.eucr.2024.102907","DOIUrl":"10.1016/j.eucr.2024.102907","url":null,"abstract":"<div><div><em>Blastomycosis dermatitidis</em> is a fungal pathogen endemic to North America. Infection from inhalation of its conidia has diffuse clinical manifestations. These can include genitourinary system infections which may manifest as ulcerative, draining skin lesions. Tissue culture is essential as anerobic bacteria and fungi grow more reliably through this medium, than with tissue swabs. A more accurate and efficient diagnosis of blastomycosis, as evidenced in this case, would have prevented prolonged treatment for presumed bacterial epididymo-orchitis and would have eliminated concern regarding possible disseminated malignancy.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"58 ","pages":"Article 102907"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11721211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We present the case of a 12-year-old girl with vesicoureteral reflux (VUR) of a solitary kidney treated using a modified hydrodistention implantation technique. A needle was set parallel to the ureteral guidewire inserted through the ureteral orifice before performing injections to correct VUR. Multi-site tandem injections were administered along the wire, which confirmed the direction and length of the ureteral tunnel. The mounds were aligned without ureteral kinking. A reduced volume of dextranomer-hyaluronic acid copolymer (Deflux®) was required to construct an effective anti-reflux tunnel. A voiding cystourethrogram confirmed VUR resolution. This technique avoided complications associated with a solitary kidney.
{"title":"Vesicoureteral reflux of a solitary kidney treated with endoscopic injection therapy comprising tandem injections administered with the assistance of a ureteral guidewire in a young girl","authors":"Tetsuji Maruyama , Kentaro Mizuno , Hidenori Nishio , Daisuke Matsumoto , Takuya Sakata , Yutaro Hayashi","doi":"10.1016/j.eucr.2024.102921","DOIUrl":"10.1016/j.eucr.2024.102921","url":null,"abstract":"<div><div>We present the case of a 12-year-old girl with vesicoureteral reflux (VUR) of a solitary kidney treated using a modified hydrodistention implantation technique. A needle was set parallel to the ureteral guidewire inserted through the ureteral orifice before performing injections to correct VUR. Multi-site tandem injections were administered along the wire, which confirmed the direction and length of the ureteral tunnel. The mounds were aligned without ureteral kinking. A reduced volume of dextranomer-hyaluronic acid copolymer (Deflux®) was required to construct an effective anti-reflux tunnel. A voiding cystourethrogram confirmed VUR resolution. This technique avoided complications associated with a solitary kidney.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"58 ","pages":"Article 102921"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11741089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.eucr.2024.102906
Satoshi Yoshikawa
This case report describes an elderly man with a history of recurrent urinary tract infections and obstructive pyelonephritis with struvite stones caused by Proteus mirabilis. Despite appropriate antibiotic treatment, the stones increased in size, necessitating alternative therapy. This case highlights the use of ascorbic acid to lower the urine pH, which contributes to the dissolution of struvite stones. Dual-energy CT was used to differentiate the stone composition for the initiation of ascorbic acid. These findings suggest that ascorbic acid can accelerate struvite stone dissolution, and that dual-energy CT is valuable for both initial diagnosis and follow-up.
{"title":"Dissolution of struvite stones with ascorbic acid","authors":"Satoshi Yoshikawa","doi":"10.1016/j.eucr.2024.102906","DOIUrl":"10.1016/j.eucr.2024.102906","url":null,"abstract":"<div><div>This case report describes an elderly man with a history of recurrent urinary tract infections and obstructive pyelonephritis with struvite stones caused by Proteus mirabilis. Despite appropriate antibiotic treatment, the stones increased in size, necessitating alternative therapy. This case highlights the use of ascorbic acid to lower the urine pH, which contributes to the dissolution of struvite stones. Dual-energy CT was used to differentiate the stone composition for the initiation of ascorbic acid. These findings suggest that ascorbic acid can accelerate struvite stone dissolution, and that dual-energy CT is valuable for both initial diagnosis and follow-up.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"58 ","pages":"Article 102906"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.eucr.2024.102902
Yuchong Qiu , Sicheng Wu , Jianyang Lv , Zhigang Ji , Jie Dong
Localized bladder amyloidosis is a rare disorder mimicking bladder tumor, with merely over 200 reported cases. Here, we report a case of a 67-year-old female presented with painless gross hematuria. A positive Congo red staining of the cystoscopy biopsy raised suspicion of bladder amyloidosis, and transurethral resection of the mass was performed. Interestingly, the histopathology of the excised mass showed pink-staining material under Hematoxylin and Eosin staining, but negative Congo red staining. This case demonstrates that a negative Congo red staining doesn't exclude amyloidosis. An accurate diagnosis should rely on a comprehensive evaluation of clinical, laboratory, radiological, and histopathological findings.
{"title":"Primary localized bladder amyloidosis with negative postoperative Congo red staining: A case report","authors":"Yuchong Qiu , Sicheng Wu , Jianyang Lv , Zhigang Ji , Jie Dong","doi":"10.1016/j.eucr.2024.102902","DOIUrl":"10.1016/j.eucr.2024.102902","url":null,"abstract":"<div><div>Localized bladder amyloidosis is a rare disorder mimicking bladder tumor, with merely over 200 reported cases. Here, we report a case of a 67-year-old female presented with painless gross hematuria. A positive Congo red staining of the cystoscopy biopsy raised suspicion of bladder amyloidosis, and transurethral resection of the mass was performed. Interestingly, the histopathology of the excised mass showed pink-staining material under Hematoxylin and Eosin staining, but negative Congo red staining. This case demonstrates that a negative Congo red staining doesn't exclude amyloidosis. An accurate diagnosis should rely on a comprehensive evaluation of clinical, laboratory, radiological, and histopathological findings.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"58 ","pages":"Article 102902"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11696844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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