Pub Date : 2025-11-26DOI: 10.1016/j.eucr.2025.103296
Joshua David Bruinsma , Matthew Chau , Hugo C. Temperley , Nicole Swarbrick , Mikhail Lozinskiy
Polyorchidism is a rare anomaly, often associated with cryptorchidism and risk of malignancy. Vanishing testis syndrome results from antenatal torsion with resorption. A 38-year-old male with prior orchiectomy for atrophic testis presented with abdominal pain. Imaging revealed a 12 cm pelvic mass. Resection confirmed pure seminoma with epididymis and rete testis but no viable parenchyma. Review of prior histology showed features of testicular regression. This case demonstrates malignant transformation in a supernumerary intra-abdominal testis with ipsilateral regression, highlighting the importance of histological review and long-term vigilance.
{"title":"Intra-abdominal seminoma in polyorchidism with ipsilateral vanishing testis syndrome: A rare case report","authors":"Joshua David Bruinsma , Matthew Chau , Hugo C. Temperley , Nicole Swarbrick , Mikhail Lozinskiy","doi":"10.1016/j.eucr.2025.103296","DOIUrl":"10.1016/j.eucr.2025.103296","url":null,"abstract":"<div><div>Polyorchidism is a rare anomaly, often associated with cryptorchidism and risk of malignancy. Vanishing testis syndrome results from antenatal torsion with resorption. A 38-year-old male with prior orchiectomy for atrophic testis presented with abdominal pain. Imaging revealed a 12 cm pelvic mass. Resection confirmed pure seminoma with epididymis and rete testis but no viable parenchyma. Review of prior histology showed features of testicular regression. This case demonstrates malignant transformation in a supernumerary intra-abdominal testis with ipsilateral regression, highlighting the importance of histological review and long-term vigilance.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103296"},"PeriodicalIF":0.4,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-26DOI: 10.1016/j.eucr.2025.103294
Miguel Gil, José Cabrita Carneiro, Ana Meireles, Luís Campos Pinheiro
Penile melanoma is a rare neoplasm with aggressive biological behaviour and a dismal prognosis. We report the case of a 65-year-old male with a pigmented nodular lesion on the glans. Histopathology confirmed the diagnosis of penile melanoma with adverse prognostic features. Lymph node involvement was already present at diagnosis. He underwent partial penectomy and robotic-assisted laparoscopic bilateral inguinal and pelvic lymph node dissection, following confirmation of lymphatic spread by fine needle aspiration cytology. Thereafter, he received adjuvant radiotherapy and was started on nivolumab. This case highlights the importance of multimodal treatment, with no recurrence after 15 months of follow-up.
{"title":"Not all penile tumours are alike: A rare case of penile melanoma","authors":"Miguel Gil, José Cabrita Carneiro, Ana Meireles, Luís Campos Pinheiro","doi":"10.1016/j.eucr.2025.103294","DOIUrl":"10.1016/j.eucr.2025.103294","url":null,"abstract":"<div><div>Penile melanoma is a rare neoplasm with aggressive biological behaviour and a dismal prognosis. We report the case of a 65-year-old male with a pigmented nodular lesion on the glans. Histopathology confirmed the diagnosis of penile melanoma with adverse prognostic features. Lymph node involvement was already present at diagnosis. He underwent partial penectomy and robotic-assisted laparoscopic bilateral inguinal and pelvic lymph node dissection, following confirmation of lymphatic spread by fine needle aspiration cytology. Thereafter, he received adjuvant radiotherapy and was started on nivolumab. This case highlights the importance of multimodal treatment, with no recurrence after 15 months of follow-up.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103294"},"PeriodicalIF":0.4,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145691037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-26DOI: 10.1016/j.eucr.2025.103295
Yuli Zheng , Xiaoxuan Wang , Shanfang Tang
Xanthogranulomatous prostatitis (XGP) is extremely rare, and its clinical symptoms or imaging findings are difficult to distinguish from those of prostate cancer. This patient presented clinically with severe urinary tract infection and urinary tract obstruction, firstly he was initially treated with antibiotics. Through conservative treatments such as anti-inflammatory and symptomatic therapies, the patient's symptoms and indicators were controlled, and the PSA value decreased to 3.4ng/ml. For patients with significant clinical inflammatory indicators, elevated PSA levels, and high MRI PI-RADS scores, the possibility of XGP should be first excluded to avoid misdiagnosis and overtreatment.
{"title":"A rare case of successful treatmeat of xanthogranulomatous prostatitis and literature reviews","authors":"Yuli Zheng , Xiaoxuan Wang , Shanfang Tang","doi":"10.1016/j.eucr.2025.103295","DOIUrl":"10.1016/j.eucr.2025.103295","url":null,"abstract":"<div><div>Xanthogranulomatous prostatitis (XGP) is extremely rare, and its clinical symptoms or imaging findings are difficult to distinguish from those of prostate cancer. This patient presented clinically with severe urinary tract infection and urinary tract obstruction, firstly he was initially treated with antibiotics. Through conservative treatments such as anti-inflammatory and symptomatic therapies, the patient's symptoms and indicators were controlled, and the PSA value decreased to 3.4ng/ml. For patients with significant clinical inflammatory indicators, elevated PSA levels, and high MRI PI-RADS scores, the possibility of XGP should be first excluded to avoid misdiagnosis and overtreatment.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103295"},"PeriodicalIF":0.4,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145691034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ureteral stenting is widely used to relieve obstruction, but rare complications such as migration may occur. We report a 60-year-old woman with recurrent nephrolithiasis who presented with pyelonephritis due to a left ureteral stone. After antibiotic therapy and double-J stent placement, she underwent three ESWL sessions. Follow-up CT showed remaining fragments and absence of the upper coil of the stent, suggesting extrarenal migration. Extrarenal displacement was confirmed on the day of ureteroscopy by fluoroscopy. The stent was removed and replaced safely; recovery was uneventful. This case highlights the importance of fluoroscopic control and follow-up imaging to reveal uncommon stent-related complications.
{"title":"Complete extrarenal migration of a double-J ureteral stent following ureteral stone management: A case report","authors":"Maachi Youssef, Elafari Amine, Bentaleb Youssef, Slaoui Amine, Karmouni Tariq, Koutani Abdellatif, Elkhader Khalid","doi":"10.1016/j.eucr.2025.103292","DOIUrl":"10.1016/j.eucr.2025.103292","url":null,"abstract":"<div><div>Ureteral stenting is widely used to relieve obstruction, but rare complications such as migration may occur. We report a 60-year-old woman with recurrent nephrolithiasis who presented with pyelonephritis due to a left ureteral stone. After antibiotic therapy and double-J stent placement, she underwent three ESWL sessions. Follow-up CT showed remaining fragments and absence of the upper coil of the stent, suggesting extrarenal migration. Extrarenal displacement was confirmed on the day of ureteroscopy by fluoroscopy. The stent was removed and replaced safely; recovery was uneventful. This case highlights the importance of fluoroscopic control and follow-up imaging to reveal uncommon stent-related complications.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103292"},"PeriodicalIF":0.4,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1016/j.eucr.2025.103291
Michael Lesgart , Steven Leonard , Francesca Montanaro , Emma Helstrom , Kenneth Richer , Abigail Keller , Nicholas Mackrides , Alexander Kutikov
Inflammatory myofibroblastic tumors (IMT) are exceedingly rare, particularly when originating in the bladder. Complete surgical resection is the gold standard treatment for IMTs. We describe a case of IMT of the urinary bladder that achieved complete radiographic and endoscopic resolution after systemic treatment with ipilimumab and nivolumab directed towards metastatic melanoma. This case is noteworthy due to the tumor's serendipitous and remarkable response to immunotherapy.
{"title":"Unexpected complete resolution of intravesical inflammatory myofibroblastic tumor after immunotherapy for melanoma: A case report","authors":"Michael Lesgart , Steven Leonard , Francesca Montanaro , Emma Helstrom , Kenneth Richer , Abigail Keller , Nicholas Mackrides , Alexander Kutikov","doi":"10.1016/j.eucr.2025.103291","DOIUrl":"10.1016/j.eucr.2025.103291","url":null,"abstract":"<div><div>Inflammatory myofibroblastic tumors (IMT) are exceedingly rare, particularly when originating in the bladder. Complete surgical resection is the gold standard treatment for IMTs. We describe a case of IMT of the urinary bladder that achieved complete radiographic and endoscopic resolution after systemic treatment with ipilimumab and nivolumab directed towards metastatic melanoma. This case is noteworthy due to the tumor's serendipitous and remarkable response to immunotherapy.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103291"},"PeriodicalIF":0.4,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1016/j.eucr.2025.103290
Aamir Bashir Raina , Sajad Ahmad Para , Ghulam Mustafa , Abdul Rouf Khawaja , Gokul Kannan , Arif Hamid Bhat
Varicocele is the most common non-ductal surgically correctable pathology affecting the male reproductive potential. It is more common on left side. Solitary right side varicocele is infrequent and if identified, pathologies like renal tumor should be considered. We report a rare case of right gonadal vessel paraganglioma presenting as a long standing isolated right-sided varicocele.
{"title":"Scary varicocele secondary to gonadal vessel paraganglioma - A rare case report","authors":"Aamir Bashir Raina , Sajad Ahmad Para , Ghulam Mustafa , Abdul Rouf Khawaja , Gokul Kannan , Arif Hamid Bhat","doi":"10.1016/j.eucr.2025.103290","DOIUrl":"10.1016/j.eucr.2025.103290","url":null,"abstract":"<div><div>Varicocele is the most common non-ductal surgically correctable pathology affecting the male reproductive potential. It is more common on left side. Solitary right side varicocele is infrequent and if identified, pathologies like renal tumor should be considered. We report a rare case of right gonadal vessel paraganglioma presenting as a long standing isolated right-sided varicocele.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103290"},"PeriodicalIF":0.4,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Primary prostatic sarcomas are extremely rare, accounting for less than 0.1 % of prostatic malignancies. They arise from mesenchymal stromal cells and exhibit aggressive behavior. We report a 45-year-old man with progressive lower urinary tract symptoms, abdominal distension, and weight loss. Imaging revealed a large pelvic mass inseparable from the prostate. Exploratory laparotomy showed a >30 cm encapsulated tumor, completely excised with partial prostate. Histopathology confirmed a high-grade undifferentiated sarcoma with heterologous differentiation. At two-year follow-up, the patient remained disease-free. Complete surgical excision remains the cornerstone of management, while multimodal therapy may be considered for high-risk or recurrent cases.
{"title":"High-grade undifferentiated prostatic sarcoma with heterologous differentiation: A rare case report and literature review","authors":"Abenezer Bogale Abera , Lijalem Mekonnen Geremew , Hailemaryam Shiferaw , Shiferaw Gedefa Fentie , Yasin Worku","doi":"10.1016/j.eucr.2025.103289","DOIUrl":"10.1016/j.eucr.2025.103289","url":null,"abstract":"<div><div>Primary prostatic sarcomas are extremely rare, accounting for less than 0.1 % of prostatic malignancies. They arise from mesenchymal stromal cells and exhibit aggressive behavior. We report a 45-year-old man with progressive lower urinary tract symptoms, abdominal distension, and weight loss. Imaging revealed a large pelvic mass inseparable from the prostate. Exploratory laparotomy showed a >30 cm encapsulated tumor, completely excised with partial prostate. Histopathology confirmed a high-grade undifferentiated sarcoma with heterologous differentiation. At two-year follow-up, the patient remained disease-free. Complete surgical excision remains the cornerstone of management, while multimodal therapy may be considered for high-risk or recurrent cases.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103289"},"PeriodicalIF":0.4,"publicationDate":"2025-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-23DOI: 10.1016/j.eucr.2025.103293
Jun Yang, Yuan-Yuan Zhu, Shao-Jun Li
Xanthogranulomatous Prostatitis (XGP) is a rare benign inflammatory condition of the prostate. Patients typically present with lower urinary tract symptoms or elevated serum prostate-specific antigen (PSA) levels. Differentiating XGP from prostate cancer (PCa) based solely on multiparametric MRI (mpMRI) findings remains challenging, as histopathological examination is the gold standard for definitive diagnosis. This case report describes a 57-year-old man diagnosed with XGP. Symptomatic remission was achieved following a 4-week course of antibiotic therapy combined with an alpha-blocker.
{"title":"Xanthogranulomatous prostatitis: A case report","authors":"Jun Yang, Yuan-Yuan Zhu, Shao-Jun Li","doi":"10.1016/j.eucr.2025.103293","DOIUrl":"10.1016/j.eucr.2025.103293","url":null,"abstract":"<div><div>Xanthogranulomatous Prostatitis (XGP) is a rare benign inflammatory condition of the prostate. Patients typically present with lower urinary tract symptoms or elevated serum prostate-specific antigen (PSA) levels. Differentiating XGP from prostate cancer (PCa) based solely on multiparametric MRI (mpMRI) findings remains challenging, as histopathological examination is the gold standard for definitive diagnosis. This case report describes a 57-year-old man diagnosed with XGP. Symptomatic remission was achieved following a 4-week course of antibiotic therapy combined with an alpha-blocker.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103293"},"PeriodicalIF":0.4,"publicationDate":"2025-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-21DOI: 10.1016/j.eucr.2025.103288
Madhavan N, Balabhaskar H, Nirmal KP, Manoj Kumar G, Sunil Ashok, Manu Jose Chirayath, Rajiv S Thomas, Ritu Raj, Amal Mohan, Abraham I Thomas, Trissia Mary George
Bladder cancer in the pediatric and adolescent population is exceedingly rare.Genetic susceptibility factors, including polymorphisms in phase II detoxifying enzymes, may play a role in early tumorigenesis. We report the case of a 16-year-old male with recurrent gross hematuria, ultimately diagnosed with low-grade papillary urothelial carcinoma following transurethral resection of bladder tumor (TURBT). Genetic analysis identified a UGT1A1 polymorphism associated with reduced enzymatic activity, a known determinant of impaired detoxification, and the patient had coexistent Gilbert's syndrome. We discuss clinical presentation, management, and the potential correlation between UGT1A1 alterations, Gilbert's syndrome, environmental carcinogen exposure, and bladder carcinogenesis.
{"title":"Low-grade non–muscle-invasive urothelial carcinoma of the bladder in a 16-year-old boy with UGT1A1 polymorphism and Gilbert's syndrome: A case report","authors":"Madhavan N, Balabhaskar H, Nirmal KP, Manoj Kumar G, Sunil Ashok, Manu Jose Chirayath, Rajiv S Thomas, Ritu Raj, Amal Mohan, Abraham I Thomas, Trissia Mary George","doi":"10.1016/j.eucr.2025.103288","DOIUrl":"10.1016/j.eucr.2025.103288","url":null,"abstract":"<div><div>Bladder cancer in the pediatric and adolescent population is exceedingly rare.Genetic susceptibility factors, including polymorphisms in phase II detoxifying enzymes, may play a role in early tumorigenesis. We report the case of a 16-year-old male with recurrent gross hematuria, ultimately diagnosed with low-grade papillary urothelial carcinoma following transurethral resection of bladder tumor (TURBT). Genetic analysis identified a UGT1A1 polymorphism associated with reduced enzymatic activity, a known determinant of impaired detoxification, and the patient had coexistent Gilbert's syndrome. We discuss clinical presentation, management, and the potential correlation between UGT1A1 alterations, Gilbert's syndrome, environmental carcinogen exposure, and bladder carcinogenesis.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103288"},"PeriodicalIF":0.4,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-20DOI: 10.1016/j.eucr.2025.103286
Yunfei Li , Zhuang Li , Junjie Zhu , Maohua Suo , Huaibin Qin , Zhengguang Luo , Yukun Xiao , Bensi Zhang , Xiaoyu Lv
{"title":"A rare case of scrotal vascular fibroblastoma with rapid growth: diagnostic challenges and pathological features","authors":"Yunfei Li , Zhuang Li , Junjie Zhu , Maohua Suo , Huaibin Qin , Zhengguang Luo , Yukun Xiao , Bensi Zhang , Xiaoyu Lv","doi":"10.1016/j.eucr.2025.103286","DOIUrl":"10.1016/j.eucr.2025.103286","url":null,"abstract":"","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103286"},"PeriodicalIF":0.4,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145580399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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