Urology Case Reports最新文献

Renal Leiomyosarcoma (LMS) is an exceptionally rare and aggressive form of RCC (renal cell carcinoma), comprising of 0.5–1% of all adult RCC. This disease constitutes a 5-year 25 % overall survival. We present a rare case of renal leiomyosarcoma in a 58 year-old Caucasian female with final pathologic staging of pT2 who underwent robotic-assisted right partial nephrectomy. Despite negative margins, given her aggressive histology, adjunctive treatment is discussed.

Urachal tumors are rare and comprise of both benign and malignant neoplasms. Epithelial origin tumors are more common than mesenchymal origin tumors. We report a case Urachal inflammatory myofibroblastic tumor (IMFT) in a 12 year old boy who presented with symptoms of lower abdominal pain and burning micturition. Upon evaluation was found to have a soft tissue mass anterior to urinary bladder wall. A laparoscopic excision of tumor was done. Histopathological and immunohistochemical examination confirmed the diagnosis of IMFT. Next generation sequencing identified FN1-ALK gene fusion.

Ovarian vein syndrome is a rare condition involving the compression of the ureter by the ovarian vein. Since it was first described, very few cases have been reported in literature. We present a case of a 37-year-old female with typical symptoms and common right-side involvement. The imaging findings on ultrasound, CT, and nuclear medicine imaging are classic for her condition.

Testicular cancer found incidentally during gender-affirming orchiectomy is infrequently reported in the literature. This report details a 27-year-old transgender woman whose testicular cancer was discovered incidentally upon routine histopathologic examination of the orchiectomy specimen. The patient did not present with any clinical signs of malignancy. There was no evidence of metastases after further workup and the patient was able to resume hormone therapy after surgery. Transgender individuals must be screened according to their natal anatomy and even in absence of clinical signs excised tissue should be examined for possible malignancy.

Balanitis xerotica obliterans (BXO) is a chronic inflammatory disease affecting the male genitalia that is mostly underdiagnosed and undertreatment. We presented a 40-year-old man with meatal stenosis and an inability to urinate. Discoloration at the tip of the penis was found, and he said it got wider as he grew up. We conducted meatotomy and meatoplasty to release obstruction. Early diagnosis is essential to avoid complications.

Primary adrenal tuberculosis is an extremely rare benign lesion that typically presents with no clinical symptoms in its early stages, making it prone to clinical misdiagnosis. We report a case of a middle-aged man initially thought to have adrenal nodules, which further examination revealed to be adrenal tuberculosis accompanied by Addison's disease. This report discusses the diagnostic approach, progressive features, and treatment options for this rare disease.

Molecular tumor profiling has become an important diagnostic for prostate cancer, allowing for personalized treatment regimens based on somatic and germline genetic information. We report a 67-year-old patient with metastatic castrate-resistant prostate cancer which was intermittently responsive to androgen-deprivation therapy, docetaxel, abiraterone, radium-223, Sipuleucel-T, and radiotherapy who ultimately demonstrated a remarkable and durable response to pembrolizumab. Our case report underlines the significance of early tumor molecular profiling in aggressive or atypical prostate cancer patients and exhibits the potential for a remarkable clinical response with immunotherapy in candidates with the appropriate tumor profiles.

A case of synchronous bilateral native kidneys papillary RCC is presented in a 48 year old patient who underwent a living donor kidney transplant 10 years prior. He was on regular immunosuppressant therapy. Despite the long term follow-up, bilateral cystic and exophytic masses were incidentally found on CT scan. Subsequent bilateral open radical nephrectomy revealed papillary RCC in both kidneys.