Ejaculatory duct cysts are uncommon urological entities that can be difficult to diagnose after prostate surgery. We report a 60-year-old man who underwent TURP for a 65 g prostate and developed hemospermia and hypospermia six months later. Pelvic MRI identified a 12 mm cyst in the ejaculatory duct region above the verumontanum, confirmed cystoscopically. Post-ejaculatory urine contained no spermatozoa, while semen analysis showed oligoasthenospermia (8 million/mL, 15 % progressive motility, volume 0.8 mL). In view of the small cyst, partial preservation of ejaculation, patient age, and completed family planning, conservative surveillance was chosen. At six months, hemospermia regressed but hypospermia persisted.
{"title":"Ejaculatory duct cyst mimicking post-TURP ejaculatory dysfunction: A diagnostic challenge in a patient with hemospermia and hypospermia","authors":"Youssef Maachi, Youssef Bentalb, Amine Zaki, Amine Slaoui, Tariq Karmouni, Abdellatif Koutani, Khalid Elkhader","doi":"10.1016/j.eucr.2025.103316","DOIUrl":"10.1016/j.eucr.2025.103316","url":null,"abstract":"<div><div>Ejaculatory duct cysts are uncommon urological entities that can be difficult to diagnose after prostate surgery. We report a 60-year-old man who underwent TURP for a 65 g prostate and developed hemospermia and hypospermia six months later. Pelvic MRI identified a 12 mm cyst in the ejaculatory duct region above the verumontanum, confirmed cystoscopically. Post-ejaculatory urine contained no spermatozoa, while semen analysis showed oligoasthenospermia (8 million/mL, 15 % progressive motility, volume 0.8 mL). In view of the small cyst, partial preservation of ejaculation, patient age, and completed family planning, conservative surveillance was chosen. At six months, hemospermia regressed but hypospermia persisted.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103316"},"PeriodicalIF":0.4,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145789828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-15DOI: 10.1016/j.eucr.2025.103321
Mauro Poggiali Gasparoni Junior , Diogo Eugenio Abreu da Silva , Andre Luiz Lima Diniz , José Anacleto Dutra de Resende Junior , Luciano Alves Favorito
We report a rare case of obturator nerve schwannoma incidentally found during laparoscopic radical prostatectomy in a 68-year-old man with a 20-year history of chronic thigh pain. Initially interpreted as lymphadenopathy on MRI, the lesion was excised via intracapsular, nerve-sparing resection. Histopathology confirmed a benign schwannoma. The patient experienced >90 % pain relief, regained urinary continence by day 30, and is recovering erectile function. At six months, he remains symptom-free. Obturator schwannomas are extremely rare and can mimic nodal disease. Minimally invasive, nerve-sparing excision during pelvic oncologic surgery is safe and effective when performed by experienced surgeons.
{"title":"Incidental obturator nerve schwannoma mimicking nodal disease during radical prostatectomy: Resolution of chronic neuropathic pain after intracapsular nerve-sparing excision","authors":"Mauro Poggiali Gasparoni Junior , Diogo Eugenio Abreu da Silva , Andre Luiz Lima Diniz , José Anacleto Dutra de Resende Junior , Luciano Alves Favorito","doi":"10.1016/j.eucr.2025.103321","DOIUrl":"10.1016/j.eucr.2025.103321","url":null,"abstract":"<div><div>We report a rare case of obturator nerve schwannoma incidentally found during laparoscopic radical prostatectomy in a 68-year-old man with a 20-year history of chronic thigh pain. Initially interpreted as lymphadenopathy on MRI, the lesion was excised via intracapsular, nerve-sparing resection. Histopathology confirmed a benign schwannoma. The patient experienced >90 % pain relief, regained urinary continence by day 30, and is recovering erectile function. At six months, he remains symptom-free. Obturator schwannomas are extremely rare and can mimic nodal disease. Minimally invasive, nerve-sparing excision during pelvic oncologic surgery is safe and effective when performed by experienced surgeons.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103321"},"PeriodicalIF":0.4,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145789822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-15DOI: 10.1016/j.eucr.2025.103314
Paulus Chandra , Santoso Chandra , Sawkar Vijay Pramod
A 71-year-old man with bothersome lower urinary tract symptoms from an enlarged prostate underwent monopolar transurethral resection of the prostate (TURP). Following the 75-min procedure, he developed hypertension, pallor, and shivering. Laboratory tests demonstrated hyponatremia, anemia, thrombocytopenia, leukocytosis, and acute liver and kidney injury. Prompt recognition and management of electrolyte and organ involvement led to rapid improvement. However, unique to this case, mild anemia and elevated creatinine remained for years. This case and review emphasize the need to anticipate multiorgan involvement, including hepatic and renal impairment, as well as potential residual effects, in patients with TURP syndrome.
{"title":"Multiorgan involvement and residual effects in transurethral resection of prostate syndrome: A case report and literature review","authors":"Paulus Chandra , Santoso Chandra , Sawkar Vijay Pramod","doi":"10.1016/j.eucr.2025.103314","DOIUrl":"10.1016/j.eucr.2025.103314","url":null,"abstract":"<div><div>A 71-year-old man with bothersome lower urinary tract symptoms from an enlarged prostate underwent monopolar transurethral resection of the prostate (TURP). Following the 75-min procedure, he developed hypertension, pallor, and shivering. Laboratory tests demonstrated hyponatremia, anemia, thrombocytopenia, leukocytosis, and acute liver and kidney injury. Prompt recognition and management of electrolyte and organ involvement led to rapid improvement. However, unique to this case, mild anemia and elevated creatinine remained for years. This case and review emphasize the need to anticipate multiorgan involvement, including hepatic and renal impairment, as well as potential residual effects, in patients with TURP syndrome.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103314"},"PeriodicalIF":0.4,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145789826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-15DOI: 10.1016/j.eucr.2025.103315
Joshua Tiro , Flavio Vasconcelas Ordones , Peter John Gilling , Lodewikus Petrus Vermeulen
Malignant mesothelioma of the tunica vaginalis testis (MMTVT) is an exceedingly rare neoplasm, representing <1 % of all mesothelioma cases. We report a 64-year-old male with prolonged occupational asbestos exposure presenting with a chronic hydrocoele. Hydrocoelectomy revealed abnormal tunica vaginalis tissue, prompting radical orchiectomy. Histology confirmed MMTVT. Subsequent hemiscrotectomy with cord excision and inguinal lymph node dissection was performed and he remains disease free on follow up. Integrated with the largest body of literature available, this case highlights the need for heightened clinical suspicion in chronic hydrocoele with asbestos exposure, and the role of radical surgery as the cornerstone of treatment.
{"title":"Malignant mesothelioma of the tunica vaginalis: A case report and comprehensive literature review","authors":"Joshua Tiro , Flavio Vasconcelas Ordones , Peter John Gilling , Lodewikus Petrus Vermeulen","doi":"10.1016/j.eucr.2025.103315","DOIUrl":"10.1016/j.eucr.2025.103315","url":null,"abstract":"<div><div>Malignant mesothelioma of the tunica vaginalis testis (MMTVT) is an exceedingly rare neoplasm, representing <1 % of all mesothelioma cases. We report a 64-year-old male with prolonged occupational asbestos exposure presenting with a chronic hydrocoele. Hydrocoelectomy revealed abnormal tunica vaginalis tissue, prompting radical orchiectomy. Histology confirmed MMTVT. Subsequent hemiscrotectomy with cord excision and inguinal lymph node dissection was performed and he remains disease free on follow up. Integrated with the largest body of literature available, this case highlights the need for heightened clinical suspicion in chronic hydrocoele with asbestos exposure, and the role of radical surgery as the cornerstone of treatment.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103315"},"PeriodicalIF":0.4,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145789827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-15DOI: 10.1016/j.eucr.2025.103317
Fumihiro Ito , Koki Kobayashi , Yurika Sawasaki , Gaku Hayashi , Shunsuke Kamijo , Akitaka Shibata , Takashi Fujita
An 86-year-old man with metastatic urothelial carcinoma developed fever, mucosal erosions, and rapidly progressive widespread erythema shortly after completing the first cycle of enfortumab vedotin (EV). Skin biopsy showed full-thickness epidermal necrosis consistent with toxic epidermal necrolysis (TEN). EV was discontinued and high-dose corticosteroids, intravenous immunoglobulin, and intensive supportive care were administered; however, the patient deteriorated rapidly and died of septic shock. This case demonstrates that EV-induced TEN may occur early and progress fulminantly, underscoring the need for prompt recognition and early dermatologic consultation.
{"title":"Early-onset fatal toxic epidermal necrolysis after first-cycle enfortumab vedotin in an elderly patient with metastatic urothelial carcinoma","authors":"Fumihiro Ito , Koki Kobayashi , Yurika Sawasaki , Gaku Hayashi , Shunsuke Kamijo , Akitaka Shibata , Takashi Fujita","doi":"10.1016/j.eucr.2025.103317","DOIUrl":"10.1016/j.eucr.2025.103317","url":null,"abstract":"<div><div>An 86-year-old man with metastatic urothelial carcinoma developed fever, mucosal erosions, and rapidly progressive widespread erythema shortly after completing the first cycle of enfortumab vedotin (EV). Skin biopsy showed full-thickness epidermal necrosis consistent with toxic epidermal necrolysis (TEN). EV was discontinued and high-dose corticosteroids, intravenous immunoglobulin, and intensive supportive care were administered; however, the patient deteriorated rapidly and died of septic shock. This case demonstrates that EV-induced TEN may occur early and progress fulminantly, underscoring the need for prompt recognition and early dermatologic consultation.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103317"},"PeriodicalIF":0.4,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145789824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-15DOI: 10.1016/j.eucr.2025.103318
Marisa Couto , Maria João Oura , Nuno Teixeira Tavares , Miguel Barbosa , Pedro Pereira , Rui Pinto , Isabel Augusto
Male genital lichen sclerosus (LS) is a chronic inflammatory disorder with malignant potential, transforming into penile squamous cell carcinoma (SCC) in up to 30 % of cases. We report a 59-year-old man diagnosed with LS in 2008 after circumcision, without follow-up. Sixteen years later, he developed a suspicious induration of the balanopreputial sulcus. Partial penectomy and lymphadenectomy revealed a pT2N3 SCC with adjacent LS. Rapid local recurrence required total penile amputation, followed by adjuvant chemotherapy. This case underscores the strong LS–SCC association and the need for early recognition, continuous surveillance, and timely multidisciplinary management to prevent delayed diagnosis and radical surgery.
{"title":"Pathway from lichen sclerosus to squamous cell carcinoma of the penis: the oncologist's perspective","authors":"Marisa Couto , Maria João Oura , Nuno Teixeira Tavares , Miguel Barbosa , Pedro Pereira , Rui Pinto , Isabel Augusto","doi":"10.1016/j.eucr.2025.103318","DOIUrl":"10.1016/j.eucr.2025.103318","url":null,"abstract":"<div><div>Male genital lichen sclerosus (LS) is a chronic inflammatory disorder with malignant potential, transforming into penile squamous cell carcinoma (SCC) in up to 30 % of cases. We report a 59-year-old man diagnosed with LS in 2008 after circumcision, without follow-up. Sixteen years later, he developed a suspicious induration of the balanopreputial sulcus. Partial penectomy and lymphadenectomy revealed a pT2N3 SCC with adjacent LS. Rapid local recurrence required total penile amputation, followed by adjuvant chemotherapy. This case underscores the strong LS–SCC association and the need for early recognition, continuous surveillance, and timely multidisciplinary management to prevent delayed diagnosis and radical surgery.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103318"},"PeriodicalIF":0.4,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145980324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-15DOI: 10.1016/j.eucr.2025.103319
Alba Rubia Escribano , Beatriz Gómez González , Alejandro Hevia Feliú , Begoña Fernández Martínez , Ana Moreno Reboiro , Alejandra Navarro Piñeiro , Ignacio González-Valcárcel De Torres , Ana Isabel Linares Quevedo , José Manuel De La Morena Gallego
Primary urethral melanoma is a rare and aggressive neoplasm with limited therapeutic evidence and typically delayed diagnosis.
We report the case of a 54-year-old woman diagnosed with urethral melanoma, treated by local excision, subsequent margin re-excision, and laparoscopic right inguinal lymphadenectomy for a palpable node, followed by adjuvant pembrolizumab, achieving favorable evolution and no recurrence at six months.
Clinical, molecular, and therapeutic aspects of this entity are reviewed, emphasizing the role of initial surgical excision, limited response to immunotherapy, and lack of standardized protocols. Optimal management requires an individualized multidisciplinary approach and further research to improve outcomes.
{"title":"Multidisciplinary management of urethral melanoma","authors":"Alba Rubia Escribano , Beatriz Gómez González , Alejandro Hevia Feliú , Begoña Fernández Martínez , Ana Moreno Reboiro , Alejandra Navarro Piñeiro , Ignacio González-Valcárcel De Torres , Ana Isabel Linares Quevedo , José Manuel De La Morena Gallego","doi":"10.1016/j.eucr.2025.103319","DOIUrl":"10.1016/j.eucr.2025.103319","url":null,"abstract":"<div><div>Primary urethral melanoma is a rare and aggressive neoplasm with limited therapeutic evidence and typically delayed diagnosis.</div><div>We report the case of a 54-year-old woman diagnosed with urethral melanoma, treated by local excision, subsequent margin re-excision, and laparoscopic right inguinal lymphadenectomy for a palpable node, followed by adjuvant pembrolizumab, achieving favorable evolution and no recurrence at six months.</div><div>Clinical, molecular, and therapeutic aspects of this entity are reviewed, emphasizing the role of initial surgical excision, limited response to immunotherapy, and lack of standardized protocols. Optimal management requires an individualized multidisciplinary approach and further research to improve outcomes.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103319"},"PeriodicalIF":0.4,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145789825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-11DOI: 10.1016/j.eucr.2025.103313
Leonardo Lamego Cardoso, Guilherme Barros de Mattos, Daniel Bianqui Guaraldo, Aline Akel, Paulo Victor de Jesus Silva, Dácio josué Souza Dias, Ricardo Miyaoka, Renato Nardi Pedro, Wilmar Azal Neto
Giant hydronephrosis is defined as the presence of more than 1 L of urine within the renal collecting system, usually resulting from ureteropelvic junction obstruction caused by congenital anomaly or impacted ureteral calculus. We report the case of a 55 years old man who developed left sided giant hydronephrosis secondary to obstructive ureterolithiasis. The patient was initially treated with percutaneous nephrostomy, draining 18 L of urine. After confirmation of non functional kidney, nephrectomy was performed. This case is reported due to its rarity and to remind the urological community to consider this diagnosis in cases of large abdominal masses.
{"title":"Giant hydronephrosis secondary to ureterolithiasis: A case report","authors":"Leonardo Lamego Cardoso, Guilherme Barros de Mattos, Daniel Bianqui Guaraldo, Aline Akel, Paulo Victor de Jesus Silva, Dácio josué Souza Dias, Ricardo Miyaoka, Renato Nardi Pedro, Wilmar Azal Neto","doi":"10.1016/j.eucr.2025.103313","DOIUrl":"10.1016/j.eucr.2025.103313","url":null,"abstract":"<div><div>Giant hydronephrosis is defined as the presence of more than 1 L of urine within the renal collecting system, usually resulting from ureteropelvic junction obstruction caused by congenital anomaly or impacted ureteral calculus. We report the case of a 55 years old man who developed left sided giant hydronephrosis secondary to obstructive ureterolithiasis. The patient was initially treated with percutaneous nephrostomy, draining 18 L of urine. After confirmation of non functional kidney, nephrectomy was performed. This case is reported due to its rarity and to remind the urological community to consider this diagnosis in cases of large abdominal masses.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103313"},"PeriodicalIF":0.4,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145789823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-08DOI: 10.1016/j.eucr.2025.103308
Jungwoo Kang , Kriti Tripathi , Rhona McMenemin , Alice Hardwick , Anjali Nandakumar , Senthil Ragupathy , Joyce Mathew , Thomas Lam
Myopericytomas are slow-growing tumours typically arising within the dermis and soft tissues of the distal extremities. We present the first reported case of an extra-testicular myopericytoma. A man in his 50s presented with a 10-year history of a right hemiscrotal mass. Ultrasonography demonstrated a solitary, vascular, extra-testicular lesion, and serum tumour markers were normal. The patient underwent complete surgical excision, and histopathological analysis confirmed a benign myopericytoma. At fourteen months postoperatively, there was no evidence of recurrence. This case expands the recognised anatomical spectrum of myopericytomas and reinforces complete surgical excision as a curative treatment.
{"title":"Case report: A rare case of extra-testicular myopericytoma","authors":"Jungwoo Kang , Kriti Tripathi , Rhona McMenemin , Alice Hardwick , Anjali Nandakumar , Senthil Ragupathy , Joyce Mathew , Thomas Lam","doi":"10.1016/j.eucr.2025.103308","DOIUrl":"10.1016/j.eucr.2025.103308","url":null,"abstract":"<div><div>Myopericytomas are slow-growing tumours typically arising within the dermis and soft tissues of the distal extremities. We present the first reported case of an extra-testicular myopericytoma. A man in his 50s presented with a 10-year history of a right hemiscrotal mass. Ultrasonography demonstrated a solitary, vascular, extra-testicular lesion, and serum tumour markers were normal. The patient underwent complete surgical excision, and histopathological analysis confirmed a benign myopericytoma. At fourteen months postoperatively, there was no evidence of recurrence. This case expands the recognised anatomical spectrum of myopericytomas and reinforces complete surgical excision as a curative treatment.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103308"},"PeriodicalIF":0.4,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-08DOI: 10.1016/j.eucr.2025.103311
Wendy Matilde Chipa Beizaga , Luis José Orbegoso Celis , Brandom Juced Torres Marigorda , Miguel Martín Aguilar Ulloque , Kilder Nicolay García Murga , Valeria Linares Vega , Fernando Jeancarlos Imán Izquierdo , Ronald Aquino-Ortega , Juana del Valle-Mendoza , Wilmer Gianfranco Silva-Caso
Disorders of sex development are conditions characterized by alterations in gonadal development that lead to discordance between chromosomal sex, gonadal sex, and phenotypic sex. We report the case of a 4 years old patient with ambiguous genitalia and 45,X/46,XY karyotype. A rudimentary uterus was visualized, and bilateral inguinal exploration was performed, during which the residual right spermatic cord was ligated and orchiectomy of the left testis located in the inguinal canal was carried out. This case highlights the relevance of clinical findings identified during physical examination and emphasizes the importance of multidisciplinary management due to the risk of gonadal malignancy.
{"title":"Urological management in a pediatric patient with mixed gonadal dysgenesis","authors":"Wendy Matilde Chipa Beizaga , Luis José Orbegoso Celis , Brandom Juced Torres Marigorda , Miguel Martín Aguilar Ulloque , Kilder Nicolay García Murga , Valeria Linares Vega , Fernando Jeancarlos Imán Izquierdo , Ronald Aquino-Ortega , Juana del Valle-Mendoza , Wilmer Gianfranco Silva-Caso","doi":"10.1016/j.eucr.2025.103311","DOIUrl":"10.1016/j.eucr.2025.103311","url":null,"abstract":"<div><div>Disorders of sex development are conditions characterized by alterations in gonadal development that lead to discordance between chromosomal sex, gonadal sex, and phenotypic sex. We report the case of a 4 years old patient with ambiguous genitalia and 45,X/46,XY karyotype. A rudimentary uterus was visualized, and bilateral inguinal exploration was performed, during which the residual right spermatic cord was ligated and orchiectomy of the left testis located in the inguinal canal was carried out. <u>This case highlights the relevance of clinical findings identified during physical examination and emphasizes the importance of multidisciplinary management due to the risk of gonadal malignancy</u>.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"64 ","pages":"Article 103311"},"PeriodicalIF":0.4,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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