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Congenital Renal arteriovenous malformation: An unusual cause of clot retention – Case report and review of the literature 先天性肾动静脉畸形:一种不寻常的凝块潴留原因——病例报告及文献复习
IF 0.4 Q4 UROLOGY & NEPHROLOGY Pub Date : 2026-01-21 DOI: 10.1016/j.eucr.2026.103354
Nicholas Nordin, Ronkino McCoy, Shimron Brown, Nikhil Gopal
A 35-year-old male with no prior medical or surgical history presented with clot retention. Cystoscopy revealed bloody efflux from the left ureteral orifice. Ureteroscopy showed clots within the left lower renal moiety. CT angiogram and renal angiography confirmed a renal arteriovenous malformation (AVM) that was successfully embolized. To our knowledge, this is the first reported case of a congenital renal AVM in a duplex collecting system. Prior cases of congenital renal AVM presenting with gross hematuria are reviewed. This is an unusual cause of gross hematuria in patients, which occasionally can be severe. Nonetheless, selective angioembolization provides excellent outcomes.
患者为35岁男性,无既往病史或手术史。膀胱镜检查显示左侧输尿管口出血。输尿管镜检查显示左肾下段有血块。CT血管造影和肾血管造影证实肾动静脉畸形(AVM),并成功栓塞。据我们所知,这是第一例报告的先天性肾动静脉畸形在双收集系统。本文回顾了以往先天性肾动静脉畸形以肉眼血尿表现的病例。这是一个不寻常的原因,肉眼血尿的病人,偶尔可以是严重的。尽管如此,选择性血管栓塞提供了良好的结果。
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引用次数: 0
Massive non-functioning Adrenocortical carcinoma presenting as acute abdomen without rupture: A case report 大块无功能的肾上腺皮质癌表现为急性腹部而无破裂:1例报告
IF 0.4 Q4 UROLOGY & NEPHROLOGY Pub Date : 2026-01-19 DOI: 10.1016/j.eucr.2026.103350
Shady H.Y.B. Girgis , Ihab H.Y. Barsoum , Shady Elia Anis , Mostafa Elgamal , Hany Yassa
Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with diverse clinical presentations. Acute abdomen is an exceptionally uncommon manifestation, typically reflecting tumor rupture. We report a 39-year-old male presenting with acute abdominal pain and a palpable left upper-quadrant mass. Imaging demonstrated a massive adrenal tumor (17.8 × 15.1 × 20.2cm). En-bloc resection with negative margins was achieved without rupture while preserving adjacent organs. Histopathology confirmed ACC. The patient remains disease-free 36 months postoperatively without adjuvant therapy. Acute abdomen can be the presenting symptom of ACC even without tumor rupture. Timely intervention can prevent possible impending rupture, enabling complete resection and favorable oncological outcomes.
摘要肾上腺皮质癌是一种罕见的侵袭性恶性肿瘤,临床表现多样。急腹症是一种罕见的表现,通常反映肿瘤破裂。我们报告一个39岁的男性表现为急性腹痛和可触及的左上腹肿块。影像学示巨大肾上腺肿瘤(17.8 × 15.1 × 20.2cm)。阴性切缘的整体切除在保留邻近器官的同时无破裂。组织病理学证实为ACC。患者术后36个月无疾病,无需辅助治疗。即使没有肿瘤破裂,急腹症也可能是ACC的主要症状。及时的干预可以预防可能即将发生的破裂,实现完全切除和良好的肿瘤预后。
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引用次数: 0
Primary renal angiosarcoma with renal vein thrombus: Case report and Review of literature 原发性肾血管肉瘤合并肾静脉血栓1例并文献复习
IF 0.4 Q4 UROLOGY & NEPHROLOGY Pub Date : 2026-01-19 DOI: 10.1016/j.eucr.2026.103351
Mauricio S. Rodríguez-Mar , Jose Manuel Torres-Zazueta , Ricardo Fernández-Ferreira , Josué Farid Elías-Delgado , Luis A. Jiménez-López , Abel A. Ricardez-Espinosa , Mariana Hernández-Ramírez
Primary angiosarcoma of the kidney is extremely rare and aggressive cancer when it presents renal vein thrombus. This presentation confers poor prognosis, with limited therapeutic options. We present a case that began with anemia and macroscopic hematuria. At diagnosis, computed tomography (CT) showed thrombosis of the left renal vein, and a radical nephrectomy was performed. Histological examination revealed a carcinoma of the collecting ducts of Bellini, with immunohistochemistry positive for epithelioid angiosarcoma.
原发性肾脏血管肉瘤是一种非常罕见的恶性肿瘤,当它表现为肾静脉血栓时。这种表现预后不良,治疗选择有限。我们报告一个以贫血和肉眼可见的血尿开始的病例。诊断时,计算机断层扫描(CT)显示左肾静脉血栓形成,并进行根治性肾切除术。组织学检查显示Bellini集合管癌,上皮样血管肉瘤免疫组化阳性。
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引用次数: 0
Impending erosion of penile prosthesis pump: Salvage management with pseudo-capsule excision and median raphe repositioning – A case report 阴茎假体泵即将发生糜烂:假包膜切除和中缝重新定位的抢救处理- 1例报告
IF 0.4 Q4 UROLOGY & NEPHROLOGY Pub Date : 2026-01-14 DOI: 10.1016/j.eucr.2026.103346
Mohammad K. Khan
Pump erosion is a rare complication of penile prosthesis implantation that often requires explantation. We present a 43-year-old diabetic male who developed impending pump erosion with scrotal skin thinning over a functional prosthesis pump. Salvage was performed by excision of the fibrotic pseudo-capsule and relocation of the pump into the median raphe, combined with antibiotic and antifungal irrigation. The patient recovered uneventfully with excellent cosmetic and functional outcomes. This case highlights pseudo-capsule excision and median raphe repositioning as a safe, effective salvage option in selected patients without infection.
泵腐蚀是阴茎假体植入术中一种罕见的并发症,通常需要外植。我们提出一个43岁的糖尿病男性谁发展迫在眉睫的泵糜烂与阴囊皮肤变薄的功能假泵。通过切除纤维化假囊和将泵重新安置到中缝中,结合抗生素和抗真菌冲洗进行抢救。患者恢复顺利,具有良好的美容和功能效果。本病例强调假包膜切除和中缝复位是一种安全、有效的无感染患者抢救选择。
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引用次数: 0
Papillary urothelial tumor of low malignant potential in a pediatric patient: case associated with Poland syndrome 小儿患者低恶性潜能乳头状尿路上皮肿瘤:与波兰综合征相关的病例
IF 0.4 Q4 UROLOGY & NEPHROLOGY Pub Date : 2026-01-14 DOI: 10.1016/j.eucr.2026.103348
Katherine Arias , Myriam Lili Ceballos , Juan Lukas Ordoñez , Edwin Abraham Medina , Manuel Duque
Papillary urothelial tumor of low malignant potential is rare in pediatric patients, accounting for only 0.1–0.4 % of bladder tumors under 20 years of age. We present the case of a 14-year-old female with Poland syndrome and history of laryngeal, nasal, and colonic polyposis presented with intermittent gross hematuria, suprapubic pain, and urinary incontinence. Transurethral resection (TUR) identified a papillary urothelial neoplasm of low malignant potential. Genetic testing revealed an ARMC4 variant (primary ciliary dyskinesia), with no known association to PUNLMP. This case highlights the importance of a stepwise approach including early imaging, histologic confirmation, and endoscopic monitoring.
低度恶性潜能的乳头状尿路上皮肿瘤在儿科患者中罕见,仅占20岁以下膀胱肿瘤的0.1 - 0.4%。我们报告一名14岁女性波兰综合征和喉,鼻和结肠息肉病史的病例,表现为间歇性肉眼血尿,耻骨上疼痛和尿失禁。经尿道尿道切除术(TUR)确定了一个低恶性潜能的乳头状尿路上皮肿瘤。基因检测显示ARMC4变异(原发性纤毛运动障碍),与PUNLMP没有已知的关联。本病例强调了阶梯式方法的重要性,包括早期成像、组织学确认和内窥镜监测。
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引用次数: 0
Clonal selection of pre-existing neuroendocrine component in prostate cancer during androgen receptor signaling inhibitor therapy: A case report 雄激素受体信号抑制剂治疗期间前列腺癌中预先存在的神经内分泌成分的克隆选择:一例报告
IF 0.4 Q4 UROLOGY & NEPHROLOGY Pub Date : 2026-01-14 DOI: 10.1016/j.eucr.2026.103347
Haruka Kubota , Toshiki Kijima , Hadzki Matsuda , Toshitaka Uematsu , Kohei Takei , Masahiro Yashi , Kazuyuki Ishida , Takao Kamai
Neuroendocrine prostate cancer (NEPC) is often considered treatment-induced. We report a case with pre-existing neuroendocrine differentiation that became evident during androgen receptor signaling inhibitor (ARSI) therapy. A 79-year-old man with metastatic prostate cancer received degarelix plus apalutamide. Prostate-specific antigen (PSA) decreased to <0.01 ng/mL. Subsequently, lung and liver metastases developed while PSA remained low, with neuron-specific enolase rising to 584 ng/mL. Liver biopsy revealed PSA-negative, neuroendocrine marker-positive carcinoma. Re-evaluation of initial biopsy demonstrated positivity for both PSA and neuroendocrine markers, indicating pre-existing neuroendocrine differentiation.
神经内分泌前列腺癌(NEPC)通常被认为是治疗引起的。我们报告一例预先存在的神经内分泌分化,在雄激素受体信号抑制剂(ARSI)治疗期间变得明显。一名患有转移性前列腺癌的79岁男性接受了degarelix + apalutamide治疗。前列腺特异性抗原(PSA)降至0.01 ng/mL。随后,在PSA保持低水平的情况下,肺和肝转移发生,神经元特异性烯醇化酶升高至584 ng/mL。肝活检显示psa阴性,神经内分泌标志物阳性。重新评估初始活检显示PSA和神经内分泌标志物阳性,表明先前存在神经内分泌分化。
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引用次数: 0
Recurrent bladder paraganglioma with peritoneal dissemination: An unusual pattern of metastatic progression. Case report and literature review 复发性膀胱副神经节瘤伴腹膜播散:一种不寻常的转移进展模式。病例报告及文献复习
IF 0.4 Q4 UROLOGY & NEPHROLOGY Pub Date : 2026-01-10 DOI: 10.1016/j.eucr.2026.103342
Paolo Guedes Oliva , Pablo Jiménez Marrero , Rubén Espino Espino , Reinaldo Marrero Domínguez , Irene Expósito Remedios , Rafael Camacho Galán
We report the case of a 26-year-old man diagnosed with multifocal bladder paraganglioma, an exceptionally rare neuroendocrine tumor. The patient presented with hypertension and adrenergic symptoms triggered by micturition, associated with elevated metanephrines and multiple pelvic lesions. He underwent complete laparoscopic resection, including partial cystectomy, achieving initial biochemical remission. Early local recurrence and subsequent peritoneal carcinomatosis, an uncommon metastatic pattern, were observed, requiring systemic therapy. This case highlights the diagnostic challenges, potential for aggressive behavior, and limited therapeutic options in metastatic bladder paraganglioma, underscoring the need for high clinical suspicion, adequate preoperative management, and long-term follow-up.
我们报告一个26岁的男子诊断为多灶性膀胱副神经节瘤,一个异常罕见的神经内分泌肿瘤。患者表现出由排尿引起的高血压和肾上腺素能症状,伴有肾上腺素升高和多发性盆腔病变。他接受了完整的腹腔镜切除术,包括部分膀胱切除术,初步生化缓解。观察到早期局部复发和随后的腹膜癌,一种罕见的转移模式,需要全身治疗。本病例强调了转移性膀胱副神经节瘤的诊断挑战、潜在的侵袭性行为和有限的治疗选择,强调了高度临床怀疑、充分的术前管理和长期随访的必要性。
{"title":"Recurrent bladder paraganglioma with peritoneal dissemination: An unusual pattern of metastatic progression. Case report and literature review","authors":"Paolo Guedes Oliva ,&nbsp;Pablo Jiménez Marrero ,&nbsp;Rubén Espino Espino ,&nbsp;Reinaldo Marrero Domínguez ,&nbsp;Irene Expósito Remedios ,&nbsp;Rafael Camacho Galán","doi":"10.1016/j.eucr.2026.103342","DOIUrl":"10.1016/j.eucr.2026.103342","url":null,"abstract":"<div><div>We report the case of a 26-year-old man diagnosed with multifocal bladder paraganglioma, an exceptionally rare neuroendocrine tumor. The patient presented with hypertension and adrenergic symptoms triggered by micturition, associated with elevated metanephrines and multiple pelvic lesions. He underwent complete laparoscopic resection, including partial cystectomy, achieving initial biochemical remission. Early local recurrence and subsequent peritoneal carcinomatosis<u>, an uncommon metastatic pattern,</u> were observed, requiring systemic therapy. This case highlights the diagnostic challenges, potential for aggressive behavior, and limited therapeutic options in metastatic bladder paraganglioma, underscoring the need for high clinical suspicion, adequate preoperative management, and long-term follow-up.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103342"},"PeriodicalIF":0.4,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145980327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A rare case of complex pyelocutaneous fistula following microwave ablation for recurrent renal cell carcinoma successfully managed with radical nephrectomy] 【微波消融治疗复发性肾癌合并根治性肾切除术成功治疗一例复杂肾盂皮瘘】
IF 0.4 Q4 UROLOGY & NEPHROLOGY Pub Date : 2026-01-10 DOI: 10.1016/j.eucr.2026.103344
Lianpeng Gao , Bo Zhu , Xiaoxia Li , Yuyun Wu , Wenbo Zhou , Jiongming Li
A complex pyelocutaneous fistula developed after microwave ablation for recurrent clear cell renal carcinoma following partial nephrectomy. The fistula persisted despite prolonged drainage, antibiotics, ureteral stenting, and other conservative measures. Definitive management required laparoscopic radical nephrectomy with complete excision of the fistulous tract and involved psoas tissue. Histopathology showed chronic inflammation without residual malignancy. This case supports early consideration of radical nephrectomy for refractory, anatomically complex pyelocutaneous fistulas.
摘要透明细胞肾癌部分切除后复发,微波消融后并发复杂肾盂皮瘘。尽管长期引流、抗生素、输尿管支架置入和其他保守措施,瘘管仍然存在。最终的治疗需要腹腔镜根治性肾切除术,完全切除瘘道和累及的腰肌组织。组织病理学表现为慢性炎症,无恶性肿瘤残留。本病例支持早期考虑根治性肾切除术治疗难治性、解剖结构复杂的肾盂皮瘘。
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引用次数: 0
Bilateral pheochromocytomas with locally advanced right adrenal tumor extending into the inferior vena cava in a suspected Von Hippel–Lindau syndrome: A case report 怀疑Von Hippel-Lindau综合征的双侧嗜铬细胞瘤伴局部进展的右肾上腺肿瘤延伸至下腔静脉1例
IF 0.4 Q4 UROLOGY & NEPHROLOGY Pub Date : 2026-01-10 DOI: 10.1016/j.eucr.2026.103343
Sami Chebbi , Houssem Bel Hadj Alouane , Mohamed Amine Oueslati , Nidham Eddine Kchir , Sami Ben Rhouma
We report a case of bilateral pheochromocytomas in a 45-year-old man with cutaneous findings suggestive of a hereditary disease. Imaging revealed a large right adrenal tumor extending into the inferior vena cava (IVC) and a smaller contralateral lesion. The patient underwent right adrenalectomy with IVC thrombectomy, while the left lesion was managed conservatively. Histopathology confirmed pheochromocytoma with extensive IVC tumor thrombus and no distant metastases. A residual IVC thrombus was treated with anticoagulation and remained stable on follow-up imaging. This case highlights the complexity of managing hereditary pheochromocytomas with vascular invasion.
我们报告一个45岁男性双侧嗜铬细胞瘤的病例,其皮肤表现提示有遗传性疾病。影像显示一个大的右肾上腺肿瘤延伸到下腔静脉(IVC)和一个小的对侧病变。患者接受了右肾上腺切除术和下腔静脉血栓切除术,同时对左肾上腺病变进行了保守治疗。组织病理学证实嗜铬细胞瘤伴广泛的下腔静脉肿瘤血栓,无远处转移。对残留的下腔静脉血栓进行抗凝治疗,并在随访成像中保持稳定。本病例强调了管理血管侵犯的遗传性嗜铬细胞瘤的复杂性。
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引用次数: 0
A case report of testicular plasmacytoma misdiagnosed as lymphoma by ultrasound 睾丸浆细胞瘤超声误诊为淋巴瘤1例
IF 0.4 Q4 UROLOGY & NEPHROLOGY Pub Date : 2026-01-10 DOI: 10.1016/j.eucr.2026.103345
Danhong Yu , Nianyu Xue
Testicular plasmacytoma is an extremely rare malignant tumour whose clinical manifestations resemble those of common testicular tumours, making preoperative diagnosis challenging. This paper reports a case of a 63-year-old male patient who presented for consultation due to'unintentionally discovering enlargement of the right scrotum for four days’. The ultrasound findings bear a striking resemblance to lymphoma, leading to misdiagnosis as lymphoma on ultrasound. Following radical orchiectomy, pathological and immunohistochemical examination confirmed the diagnosis of plasmacytoma. Although rare, testicular plasmacytoma should be considered as part of the differential diagnosis for testicular masses.
睾丸浆细胞瘤是一种极为罕见的恶性肿瘤,其临床表现与常见的睾丸肿瘤相似,使术前诊断具有挑战性。本文报告一例63岁男性患者因“无意中发现右侧阴囊肿大4天”而就诊。超声检查结果与淋巴瘤惊人的相似,导致超声误诊为淋巴瘤。在根治性睾丸切除术后,病理和免疫组织化学检查证实了浆细胞瘤的诊断。虽然罕见,但睾丸浆细胞瘤应被视为睾丸肿块鉴别诊断的一部分。
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引用次数: 0
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Urology Case Reports
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