Toshiyuki Mitsuhashi, F. Sato, Hidetaka Yamamoto, T. Ono, H. Umeno
{"title":"Parotid gland metastases as a diagnostic clue to scalp angiosarcoma: A case report","authors":"Toshiyuki Mitsuhashi, F. Sato, Hidetaka Yamamoto, T. Ono, H. Umeno","doi":"10.5981/jjhnc.49.20","DOIUrl":"https://doi.org/10.5981/jjhnc.49.20","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kai Kanemoto, Masafumi Yoshida, Asayo Furukawa, N. Kitahara
A case of metastasis to the thyroid gland from supraglottic cancer: There are few reports in the literature of metastasis of head and neck cancer to the thyroid gland. We report a case of metastasis to the thyroid gland from supraglottic cancer. The case was an 80-year-old female, cT2N3bM0, with right cervical lymph node metastasis surrounding the carotid artery. She was treated with Pembrolizumab after radiotherapy. CT imaging after seven courses of Pembrolizumab showed an increasing low-density area in the thyroid gland. Keratinized atypical cells on cytology and histology suggested thyroid metastasis of supraglottic carcinoma. Tracheostomy was performed due to airway stenosis caused by metastatic lesions. Metastatic thyroid cancer can cause airway stenosis and bleeding as it progresses. The possibility of metastatic thyroid cancer should be considered when neoplastic lesions or thyroid function abnormalities are observed in the thyroid gland during treatment for squamous cell carcinoma of the head and neck.
{"title":"A case of metastasis to the thyroid gland from supraglottic cancer","authors":"Kai Kanemoto, Masafumi Yoshida, Asayo Furukawa, N. Kitahara","doi":"10.5981/jjhnc.48.308","DOIUrl":"https://doi.org/10.5981/jjhnc.48.308","url":null,"abstract":"A case of metastasis to the thyroid gland from supraglottic cancer: There are few reports in the literature of metastasis of head and neck cancer to the thyroid gland. We report a case of metastasis to the thyroid gland from supraglottic cancer. The case was an 80-year-old female, cT2N3bM0, with right cervical lymph node metastasis surrounding the carotid artery. She was treated with Pembrolizumab after radiotherapy. CT imaging after seven courses of Pembrolizumab showed an increasing low-density area in the thyroid gland. Keratinized atypical cells on cytology and histology suggested thyroid metastasis of supraglottic carcinoma. Tracheostomy was performed due to airway stenosis caused by metastatic lesions. Metastatic thyroid cancer can cause airway stenosis and bleeding as it progresses. The possibility of metastatic thyroid cancer should be considered when neoplastic lesions or thyroid function abnormalities are observed in the thyroid gland during treatment for squamous cell carcinoma of the head and neck.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Mochizuki, Yuki Yamaguchi, Kazutaka Takeuchi, Atsushi Imai, Y. Takizawa, K. Misawa
{"title":"Two cases of head and neck cancer treated with endovascular procedure for carotid blowout syndrome","authors":"D. Mochizuki, Yuki Yamaguchi, Kazutaka Takeuchi, Atsushi Imai, Y. Takizawa, K. Misawa","doi":"10.5981/jjhnc.48.344","DOIUrl":"https://doi.org/10.5981/jjhnc.48.344","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"166 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Okano, K. Matsuura, R. Hayashi, Masashi Wakabayashi, Yohei Morishita, Toshifumi Tomioka, T. Shinozaki
Background: In the treatment of cancer in the elderly, we experience cases in which the outcomes cannot be followed as planned even if wound healing is good. In recent years, it has been globally recommended to carry out a geriatric assessment （GA） to identify risks in advance and perform necessary interventions. Materials and methods: GA was performed from August 2019 to March 2020 for 105 patients aged 65 and over who were scheduled for surgery in our department. We conducted a retrospective study to investigate the relationship between GA and postoperative outcomes, such as complications, delirium, and non-home discharge. Results: Non-home discharge was positive for IADL in all cases and was associated with MOS and reconstructive surgery （p=0.01, 0.01）. All cases had gastrostomy or tracheal stoma. Reconstructive surgery tended to be associated with both complications and delirium （p=0.08, 0.05）. Consideration: Non-home discharge is considered to be highly probable in case of postoperative gastric fistula or tracheal stoma, IADL positive, and MOS positive or reconstructive surgery. Conclusions: GA was performed on elderly patients scheduled for surgery in our department, and a relationship between non-home discharge and GA tools was found.
{"title":"Evaluation of geriatric assessment for head and neck cancer surgery","authors":"W. Okano, K. Matsuura, R. Hayashi, Masashi Wakabayashi, Yohei Morishita, Toshifumi Tomioka, T. Shinozaki","doi":"10.5981/jjhnc.48.261","DOIUrl":"https://doi.org/10.5981/jjhnc.48.261","url":null,"abstract":"Background: In the treatment of cancer in the elderly, we experience cases in which the outcomes cannot be followed as planned even if wound healing is good. In recent years, it has been globally recommended to carry out a geriatric assessment （GA） to identify risks in advance and perform necessary interventions. Materials and methods: GA was performed from August 2019 to March 2020 for 105 patients aged 65 and over who were scheduled for surgery in our department. We conducted a retrospective study to investigate the relationship between GA and postoperative outcomes, such as complications, delirium, and non-home discharge. Results: Non-home discharge was positive for IADL in all cases and was associated with MOS and reconstructive surgery （p=0.01, 0.01）. All cases had gastrostomy or tracheal stoma. Reconstructive surgery tended to be associated with both complications and delirium （p=0.08, 0.05）. Consideration: Non-home discharge is considered to be highly probable in case of postoperative gastric fistula or tracheal stoma, IADL positive, and MOS positive or reconstructive surgery. Conclusions: GA was performed on elderly patients scheduled for surgery in our department, and a relationship between non-home discharge and GA tools was found.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gaku Takano, D. Kawakita, T. Matoba, Keisuke Oguri, Akihiro Murashima, K. Minohara, H. Tsuge, Ayano Matsumura, Wataru Hojo, Koji Tsukamoto, Ikuma Harata, S. Maseki, Taijiro Ozawa, Shoji Mitsuya, K. Moribe, Shin-ichi Iwasaki
Lenvatinib is a molecular targeted drug indicated for unresectable radioiodine refractory thyroid cancer, but predictors of therapeutic prognosis have not been established. In this study, we retrospectively reviewed histopathological features and clinical factors in 30 cases of unresectable thyroid cancer treated with lenvatinib at Nagoya City University Hospital and related facilities, and analyzed the effects on survival. The median follow-up was 20 months, the 1-year overall survival rate was 71.2％, and the 1-year progression-free survival rate was 63.0％. The histological types were papillary carcinoma in 17 cases, undifferentiated carcinoma in 5 cases, follicular carcinoma in 3 cases, medullary carcinoma in 2 cases, poorly differentiated carcinoma in 2 cases, and squamous cell carcinoma in 1 case. The progression-free survival rate was significantly better in cases in which tumor shrinkage was observed at 8 weeks after administration, cases with differentiated carcinoma, cases in which the neutrophil-lymphocyte ratio （NLR） was ≤ 3, and cases in which the Glasgow prognostic score （GPS） was 0. It is suggested that NLR and GPS may be new predictors of prognosis.
{"title":"Clinical analysis of lenvatinib therapy for unresectable thyroid cancer at Nagoya City University Hospital and related facilities","authors":"Gaku Takano, D. Kawakita, T. Matoba, Keisuke Oguri, Akihiro Murashima, K. Minohara, H. Tsuge, Ayano Matsumura, Wataru Hojo, Koji Tsukamoto, Ikuma Harata, S. Maseki, Taijiro Ozawa, Shoji Mitsuya, K. Moribe, Shin-ichi Iwasaki","doi":"10.5981/jjhnc.48.7","DOIUrl":"https://doi.org/10.5981/jjhnc.48.7","url":null,"abstract":"Lenvatinib is a molecular targeted drug indicated for unresectable radioiodine refractory thyroid cancer, but predictors of therapeutic prognosis have not been established. In this study, we retrospectively reviewed histopathological features and clinical factors in 30 cases of unresectable thyroid cancer treated with lenvatinib at Nagoya City University Hospital and related facilities, and analyzed the effects on survival. The median follow-up was 20 months, the 1-year overall survival rate was 71.2％, and the 1-year progression-free survival rate was 63.0％. The histological types were papillary carcinoma in 17 cases, undifferentiated carcinoma in 5 cases, follicular carcinoma in 3 cases, medullary carcinoma in 2 cases, poorly differentiated carcinoma in 2 cases, and squamous cell carcinoma in 1 case. The progression-free survival rate was significantly better in cases in which tumor shrinkage was observed at 8 weeks after administration, cases with differentiated carcinoma, cases in which the neutrophil-lymphocyte ratio （NLR） was ≤ 3, and cases in which the Glasgow prognostic score （GPS） was 0. It is suggested that NLR and GPS may be new predictors of prognosis.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ayana Komurasaki, Koji Ushiro, Katsuhiro Yoshikawa
Although malignancies of the eyelid are relatively rare, it is necessary to know the characteristics of eyelid malignancy because head and neck surgeons are required to treat patients with cervical lymph node metastases. We report a case of primary squamous cell carcinoma of the lower eyelid conjunctiva with parotid and cervical lymph node metastases. The patient was an 80-year-old woman. She had been diagnosed as having conjunctivitis with eye discharge in the left eye for about 6 months and had been under observation at her local ophthalmologist. Two to three months ago, she noticed swelling of the left preauricular and upper neck, and was referred to our department. A 15-mm-large protruded lesion on the left lower eyelid conjunctiva, a hard nodule in the parotid gland, and enlarged lymph nodes in the upper-left cervical region were found, all of which were diagnosed as squamous cell carcinoma by fine-needle aspiration cytology. With the diagnosis of squamous cell carcinoma of the lower eyelid with metastases to the parotid gland and cervical lymph nodes, the patient underwent resection of the malignant lower eyelid tumor, total parotidectomy, neck dissection on the affected side, and reconstruction of the lower eyelid with a hard palatal mucosal flap and malar flap. Postoperative radiation therapy was performed on the affected side of the neck, and the patient is currently undergoing outpatient follow-up with no signs of recurrence for approximately one year after the surgery.
{"title":"A case of primary squamous cell carcinoma of the eyelid conjunctiva with parotid and cervical lymph node metastases","authors":"Ayana Komurasaki, Koji Ushiro, Katsuhiro Yoshikawa","doi":"10.5981/jjhnc.48.280","DOIUrl":"https://doi.org/10.5981/jjhnc.48.280","url":null,"abstract":"Although malignancies of the eyelid are relatively rare, it is necessary to know the characteristics of eyelid malignancy because head and neck surgeons are required to treat patients with cervical lymph node metastases. We report a case of primary squamous cell carcinoma of the lower eyelid conjunctiva with parotid and cervical lymph node metastases. The patient was an 80-year-old woman. She had been diagnosed as having conjunctivitis with eye discharge in the left eye for about 6 months and had been under observation at her local ophthalmologist. Two to three months ago, she noticed swelling of the left preauricular and upper neck, and was referred to our department. A 15-mm-large protruded lesion on the left lower eyelid conjunctiva, a hard nodule in the parotid gland, and enlarged lymph nodes in the upper-left cervical region were found, all of which were diagnosed as squamous cell carcinoma by fine-needle aspiration cytology. With the diagnosis of squamous cell carcinoma of the lower eyelid with metastases to the parotid gland and cervical lymph nodes, the patient underwent resection of the malignant lower eyelid tumor, total parotidectomy, neck dissection on the affected side, and reconstruction of the lower eyelid with a hard palatal mucosal flap and malar flap. Postoperative radiation therapy was performed on the affected side of the neck, and the patient is currently undergoing outpatient follow-up with no signs of recurrence for approximately one year after the surgery.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
and Various functional disorders are presented after surgery for oral cancer due to changes in anatomical struc-ture and muscle weakness. In particular, maxillary bone deficiency may induce masticatory, swallowing, and articulatory disorders associated with the communication between the oral cavity and paranasal sinuses. Jaw dentures have been conventionally used for such cases, with various degrees of functional recovery depending on the condition of the oral cavity. In this study, we assessed the masticatory, swallowing, and articulatory functions of 20 maxillary defect patients （mean who had a maxillary prosthesis fabricated and were assessable between 2014 and 2021. In the functional assessments, the degrees of functional recovery differed depending on various factors such as remaining teeth and defect status. Maxillary prostheses can contribute to postoperative functional recovery, while multisensory assessments in-cluding subjective and objective assessments are required. It is necessary to study functional assessments for uniform use in various cases.
{"title":"Assessment of masticatory, swallowing, and articulatory functions in patients with maxillary prosthesis","authors":"Asana Kamohara, R. Aijima, A. Danjo, Y. Yamashita","doi":"10.5981/jjhnc.48.21","DOIUrl":"https://doi.org/10.5981/jjhnc.48.21","url":null,"abstract":"and Various functional disorders are presented after surgery for oral cancer due to changes in anatomical struc-ture and muscle weakness. In particular, maxillary bone deficiency may induce masticatory, swallowing, and articulatory disorders associated with the communication between the oral cavity and paranasal sinuses. Jaw dentures have been conventionally used for such cases, with various degrees of functional recovery depending on the condition of the oral cavity. In this study, we assessed the masticatory, swallowing, and articulatory functions of 20 maxillary defect patients （mean who had a maxillary prosthesis fabricated and were assessable between 2014 and 2021. In the functional assessments, the degrees of functional recovery differed depending on various factors such as remaining teeth and defect status. Maxillary prostheses can contribute to postoperative functional recovery, while multisensory assessments in-cluding subjective and objective assessments are required. It is necessary to study functional assessments for uniform use in various cases.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71244010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Fushimi, Y. Tada, T. Masubuchi, Morio Yamazaki, Kenji Hanyu, N. Tanaka, Yukiomi Kushihashi, Mayu Yamauchi, S. Sugiyama, K. Miura
Although the incidence of para-hyoid lymph nodes is not very high, ranging from 1.6％ to 8.0％, the salvage rate is remarkably low at 30％ when found as recurrence. In our own study of 315 cases of tongue cancer, the metastasis rate of the para-hyoid lymph nodes was 2.8％, the salvage rate was 14％ when found as recurrence, and the 2-year survival rate was 27.8％. Our technique requires only 5-10 minutes of surgery, with minimal blood loss and no complications, and it is thus considered acceptable to add elective para-hyoid lymph node dissection at the time of neck dissection for its control. However, the anatomical location of the metastasis was un-clear, and the extent of the dissection was not clear. Therefore, we reviewed 9 cases from our own experience and 36 cases from 22 papers, and found that metastasis around the lingual vein on the hyoglossus muscle was common. In this article, we describe the specific surgical method of para-hyoid lymph node dissection based on the clinical site of metastasis, and present a case in which metastasis was actually found after elective dissection.
{"title":"How to dissect the para-hyoid lymph nodes for tongue cancer","authors":"C. Fushimi, Y. Tada, T. Masubuchi, Morio Yamazaki, Kenji Hanyu, N. Tanaka, Yukiomi Kushihashi, Mayu Yamauchi, S. Sugiyama, K. Miura","doi":"10.5981/jjhnc.48.14","DOIUrl":"https://doi.org/10.5981/jjhnc.48.14","url":null,"abstract":"Although the incidence of para-hyoid lymph nodes is not very high, ranging from 1.6％ to 8.0％, the salvage rate is remarkably low at 30％ when found as recurrence. In our own study of 315 cases of tongue cancer, the metastasis rate of the para-hyoid lymph nodes was 2.8％, the salvage rate was 14％ when found as recurrence, and the 2-year survival rate was 27.8％. Our technique requires only 5-10 minutes of surgery, with minimal blood loss and no complications, and it is thus considered acceptable to add elective para-hyoid lymph node dissection at the time of neck dissection for its control. However, the anatomical location of the metastasis was un-clear, and the extent of the dissection was not clear. Therefore, we reviewed 9 cases from our own experience and 36 cases from 22 papers, and found that metastasis around the lingual vein on the hyoglossus muscle was common. In this article, we describe the specific surgical method of para-hyoid lymph node dissection based on the clinical site of metastasis, and present a case in which metastasis was actually found after elective dissection.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Supportive care in head and neck cancer surgery","authors":"T. Shinozaki, K. Matsuura","doi":"10.5981/jjhnc.48.313","DOIUrl":"https://doi.org/10.5981/jjhnc.48.313","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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