Pub Date : 2021-05-20DOI: 10.46646/sakh-2021-2-248-252
D. Brinkevich, S. Brinkevich, H. Kiyavitskaya, A. Kiyko
The accumulation of в-emitting radionuclides during irradiation of a liquid target of the Cyclone 18/9 HC commercial cyclotron and the production of radiopharmaceuticals (RP) based on 18F was studied by liquid scintillation spectroscopy. It is shown that with prolonged use of the target in the в-spectra of regenerated water [18O] H2O and ready-made RP [18F] NaF, in addition to the maximum due to tritium, a number of maxima appear in both the low-and high-energy parts of the spectrum. Storage for 3 months leads to a significant transformation of the spectra - the intensity of the low-energy wing of the regenerated water spectrum decreases sharply, the maximum in the 300 channel region disappears, while the intensity of the high-energy wing decreases not so dramatically. It was found that the tritium content in the regenerated water can be reliably estimated only after storage for 3 months.
{"title":"BETA-RADIATING RADIONUCLIDES FORMED IN A WATER TARGET OF A COMMERCIAL CYCLOTRON","authors":"D. Brinkevich, S. Brinkevich, H. Kiyavitskaya, A. Kiyko","doi":"10.46646/sakh-2021-2-248-252","DOIUrl":"https://doi.org/10.46646/sakh-2021-2-248-252","url":null,"abstract":"The accumulation of в-emitting radionuclides during irradiation of a liquid target of the Cyclone 18/9 HC commercial cyclotron and the production of radiopharmaceuticals (RP) based on 18F was studied by liquid scintillation spectroscopy. It is shown that with prolonged use of the target in the в-spectra of regenerated water [18O] H2O and ready-made RP [18F] NaF, in addition to the maximum due to tritium, a number of maxima appear in both the low-and high-energy parts of the spectrum. Storage for 3 months leads to a significant transformation of the spectra - the intensity of the low-energy wing of the regenerated water spectrum decreases sharply, the maximum in the 300 channel region disappears, while the intensity of the high-energy wing decreases not so dramatically. It was found that the tritium content in the regenerated water can be reliably estimated only after storage for 3 months.","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126971973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-20DOI: 10.46646/sakh-2021-2-181-184
T. A. Korolko, I. Rovenskaya
This article presents an analysis of the main issues in the field of handling objects of the plant world. The features of the use, accounting, removal of plant objects, as well as the conditions for the implementation of compensation measures, are discussed in detail.
{"title":"THE ANALYSIS OF LEGISLATIVE DOCUMENTS OF THE REPUBLIC OF BELARUS IN THE FIELD OF HANDLING OBJECTS OF THE PLANT WORLD","authors":"T. A. Korolko, I. Rovenskaya","doi":"10.46646/sakh-2021-2-181-184","DOIUrl":"https://doi.org/10.46646/sakh-2021-2-181-184","url":null,"abstract":"This article presents an analysis of the main issues in the field of handling objects of the plant world. The features of the use, accounting, removal of plant objects, as well as the conditions for the implementation of compensation measures, are discussed in detail.","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122202285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-20DOI: 10.46646/sakh-2021-2-125-128
E. Tarun, E. A. Staselovich, P. Y. Krasovskaya, T. M. Halavach, R. Romanovich
{"title":"ANTIOXIDANT ACTIVITY OF WHEY AND COLOSTRUM HYDROLYZATES COMPLEXES WITH CYCLODEXTRIN","authors":"E. Tarun, E. A. Staselovich, P. Y. Krasovskaya, T. M. Halavach, R. Romanovich","doi":"10.46646/sakh-2021-2-125-128","DOIUrl":"https://doi.org/10.46646/sakh-2021-2-125-128","url":null,"abstract":"","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122205415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-20DOI: 10.46646/sakh-2021-2-20-23
L. Birichevskaya, M. Vinter, A. A. Doroshevich, M. Khancheuski, E. Kvasyuk, A. Zinchenko
Modified nucleoside 8-bromoadenosine possessing high reactive capacity may serve as a basic compound for the synthesis of a large number of purine antimetabolites showing potentially therapeutic activities toward several tumor and viral diseases. In this study, 8-bromoadenosine was produced by a simple eco-friendly procedure following the treatment of nucleoside precursor adenosine with aqueous bromine solution. In the course of enzymatic transphosphatidylation reaction, the first synthesis of phospholipid derivative of the above-mentioned nucleoside -5‘-(1,2-dimyristoyl phosphatidyl)-8-bromoadenosine was accomplished. Novel compounds may presumably act as non-toxic progenitors of bioactive antimetabolites to be used in drug formulas.
{"title":"SYNTHESIS OF THE MODIFIED NUCLEOSIDE 8-BROMADENOSINE AND ITS PHOSPHOLIPID DERIVATIVE","authors":"L. Birichevskaya, M. Vinter, A. A. Doroshevich, M. Khancheuski, E. Kvasyuk, A. Zinchenko","doi":"10.46646/sakh-2021-2-20-23","DOIUrl":"https://doi.org/10.46646/sakh-2021-2-20-23","url":null,"abstract":"Modified nucleoside 8-bromoadenosine possessing high reactive capacity may serve as a basic compound for the synthesis of a large number of purine antimetabolites showing potentially therapeutic activities toward several tumor and viral diseases. In this study, 8-bromoadenosine was produced by a simple eco-friendly procedure following the treatment of nucleoside precursor adenosine with aqueous bromine solution. In the course of enzymatic transphosphatidylation reaction, the first synthesis of phospholipid derivative of the above-mentioned nucleoside -5‘-(1,2-dimyristoyl phosphatidyl)-8-bromoadenosine was accomplished. Novel compounds may presumably act as non-toxic progenitors of bioactive antimetabolites to be used in drug formulas.","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129502623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-20DOI: 10.46646/sakh-2021-2-346-348
E. Kotlyarova
The problem of negative environmental impacts of various types on the environment of built-up territories from the operation of capital construction and urban facilities is currently especially urgent. To solve this problem, at the first stage of the study, a study was made of existing scientific approaches to assessing the state of the environment and the choice of a scientific basis for subsequent studies. Improving the existing scientific base in order to minimize the shortcomings of the available approaches can reduce the risk for society from the increase in anthropogenic pressure on the environment and bring closer the achievement of the global goal in the field of sustainable development of urban areas.
{"title":"SCIENTIFIC BASIS OF ENSURING ENVIRONMENTAL SAFETY OF URBANIZED TERRITORIES","authors":"E. Kotlyarova","doi":"10.46646/sakh-2021-2-346-348","DOIUrl":"https://doi.org/10.46646/sakh-2021-2-346-348","url":null,"abstract":"The problem of negative environmental impacts of various types on the environment of built-up territories from the operation of capital construction and urban facilities is currently especially urgent. To solve this problem, at the first stage of the study, a study was made of existing scientific approaches to assessing the state of the environment and the choice of a scientific basis for subsequent studies. Improving the existing scientific base in order to minimize the shortcomings of the available approaches can reduce the risk for society from the increase in anthropogenic pressure on the environment and bring closer the achievement of the global goal in the field of sustainable development of urban areas.","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130028607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-20DOI: 10.46646/sakh-2021-2-155-158
O. Boyarkin, A. Kapskaya
Predicting solar flares is an important task in solar physics. The occurrence of solar flares is highly dependent on the structure and topology of the Sun’s magnetic fields. Disturbances caused by solar flares affect the operation of ground-based communications, navigation, warning systems, disrupt the functioning of on-board electronic equipment on space objects and aircrafts. In connection with these factors, there is an issue of predicting this phenomenon. This work investigates the process of occurrence of solar flares, the development of methods for predicting them and the difficulties that arise in this case. Also it presents one of the most common methods of solar flares.
{"title":"SOLAR FLARES AND THEIR PREDICTION METHODS","authors":"O. Boyarkin, A. Kapskaya","doi":"10.46646/sakh-2021-2-155-158","DOIUrl":"https://doi.org/10.46646/sakh-2021-2-155-158","url":null,"abstract":"Predicting solar flares is an important task in solar physics. The occurrence of solar flares is highly dependent on the structure and topology of the Sun’s magnetic fields. Disturbances caused by solar flares affect the operation of ground-based communications, navigation, warning systems, disrupt the functioning of on-board electronic equipment on space objects and aircrafts. In connection with these factors, there is an issue of predicting this phenomenon. This work investigates the process of occurrence of solar flares, the development of methods for predicting them and the difficulties that arise in this case. Also it presents one of the most common methods of solar flares.","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":"12 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133052909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-20DOI: 10.46646/sakh-2021-2-58-62
A. S. Lyulchenko
For decades, cardiovascular diseases have been the leading cause of disability and death worldwide. Among athletes, the risk of cardiovascular disease increases significantly due to extreme physical exertion. Genotyping of the DNA samples of athletes and the control group based on the selected candidate genes for the pathology of the cardiovascular system was carried out. Carriers of unfavorable genotypes that significantly increase the risk of thrombosis were identified in the formed groups: dangerous mutations of blood clotting factors II and V were detected in 3.2 % of gymnasts and 17.1% of representatives of fire and rescue sports.
{"title":"ANALYSIS OF THE FREQUENCY OF OCCURRENCE OF MOLECULAR GENETIC MARKERS OF PREDISPOSITION TO CARDIOVASCULAR PATHOLOGY IN ATHLETES","authors":"A. S. Lyulchenko","doi":"10.46646/sakh-2021-2-58-62","DOIUrl":"https://doi.org/10.46646/sakh-2021-2-58-62","url":null,"abstract":"For decades, cardiovascular diseases have been the leading cause of disability and death worldwide. Among athletes, the risk of cardiovascular disease increases significantly due to extreme physical exertion. Genotyping of the DNA samples of athletes and the control group based on the selected candidate genes for the pathology of the cardiovascular system was carried out. Carriers of unfavorable genotypes that significantly increase the risk of thrombosis were identified in the formed groups: dangerous mutations of blood clotting factors II and V were detected in 3.2 % of gymnasts and 17.1% of representatives of fire and rescue sports.","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123886392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-20DOI: 10.46646/sakh-2021-2-241-244
M. Y. Barysevich
The article presents the overview of the results of the implementation of the programs of the joint activity of Belarus and Russia in overcoming the consequences of the Chernobyl disaster within the Union State. The information that concerns the goals, objectivities, and main implemented activities is provided.
{"title":"THE UNION STATE PROGRAMS ON THE CHERNOBYL SUBJECT: THE MAIN RESULTS","authors":"M. Y. Barysevich","doi":"10.46646/sakh-2021-2-241-244","DOIUrl":"https://doi.org/10.46646/sakh-2021-2-241-244","url":null,"abstract":"The article presents the overview of the results of the implementation of the programs of the joint activity of Belarus and Russia in overcoming the consequences of the Chernobyl disaster within the Union State. The information that concerns the goals, objectivities, and main implemented activities is provided.","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128659004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-20DOI: 10.46646/sakh-2021-2-422-424
A. Sokolova
The main regularities of the territorial distribution and composition of hydromineral resources of the Republic of Belarus are considered. An environmental and geographical assessment of the resources and prospects for the use of sapropels in the country was carried out. It has been established that Belarus independently meets its needs in providing health resort facilities of the country with medicinal brines, as well as sapropel and peat mud, which makes it possible to strengthen the medical and health-improving base of health facilities in Belarus, and to develop the tourist business in the country.
{"title":"ECOLOGICAL, GEOGRAPHICAL AND HISTORICAL ASPECTS OF THE STUDY OF HYDROMINERAL RESOURCES OF THE REPUBLIC OF BELARUS","authors":"A. Sokolova","doi":"10.46646/sakh-2021-2-422-424","DOIUrl":"https://doi.org/10.46646/sakh-2021-2-422-424","url":null,"abstract":"The main regularities of the territorial distribution and composition of hydromineral resources of the Republic of Belarus are considered. An environmental and geographical assessment of the resources and prospects for the use of sapropels in the country was carried out. It has been established that Belarus independently meets its needs in providing health resort facilities of the country with medicinal brines, as well as sapropel and peat mud, which makes it possible to strengthen the medical and health-improving base of health facilities in Belarus, and to develop the tourist business in the country.","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117025221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-20DOI: 10.46646/sakh-2021-2-398-401
M. Atroshko, S. Albasri
The paper presents the data of semi-empirical and theoretical calculations of molecules in the medium of the solvent, their absorption spectrum and the optimized structure with the value of the total energy of the system.
本文给出了分子在溶剂介质中的半经验和理论计算数据，以及它们的吸收光谱和系统总能量值的优化结构。
{"title":"QUANTUM-CHEMICAL CALCULATION OF FLUDARABINE-P WITH EMOXIPINE SALT (F-PE)","authors":"M. Atroshko, S. Albasri","doi":"10.46646/sakh-2021-2-398-401","DOIUrl":"https://doi.org/10.46646/sakh-2021-2-398-401","url":null,"abstract":"The paper presents the data of semi-empirical and theoretical calculations of molecules in the medium of the solvent, their absorption spectrum and the optimized structure with the value of the total energy of the system.","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117336659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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