Pub Date : 2022-01-01DOI: 10.53141/qacp.2022.249-253
Sofia Colaceci, Achielle Cernigliaro, S. S. Alegiani
{"title":"Sindrome della morte improvvisa del lattante (SIDS) in Sicilia: una valutazione dei principali determinanti di accudimento","authors":"Sofia Colaceci, Achielle Cernigliaro, S. S. Alegiani","doi":"10.53141/qacp.2022.249-253","DOIUrl":"https://doi.org/10.53141/qacp.2022.249-253","url":null,"abstract":"","PeriodicalId":39791,"journal":{"name":"Quaderni ACP","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70772560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.53141/qacp.2022.200-205
Melodie O. Aricò, P. Belleri, Elena Cattazzo, Lucia Del Vecchio, G. Pagano
HyperCKemia and rhabdomyolysis are sides of the same coin. In pediatric age, in most cases, the etiology is infectious in origin with a favorable course. However, the persistence of elevated CK values over time should lead to suspicion of genetic/ hereditary causes that may also require the involvement of other specialists. Rhabdomyolysis is an urgent concern because of the possible evolution into acute renal failure requiring appropriate fluid management and aggressive treatment of electrolyte disorders.
{"title":"Approccio al bambino con iperCKemia e rabdomiolisi in pronto soccorso pediatrico","authors":"Melodie O. Aricò, P. Belleri, Elena Cattazzo, Lucia Del Vecchio, G. Pagano","doi":"10.53141/qacp.2022.200-205","DOIUrl":"https://doi.org/10.53141/qacp.2022.200-205","url":null,"abstract":"HyperCKemia and rhabdomyolysis are sides of the same coin. In pediatric age, in most cases, the etiology is infectious in origin with a favorable course. However, the persistence of elevated CK values over time should lead to suspicion of genetic/ hereditary causes that may also require the involvement of other specialists. Rhabdomyolysis is an urgent concern because of the possible evolution into acute renal failure requiring appropriate fluid management and aggressive treatment of electrolyte disorders.","PeriodicalId":39791,"journal":{"name":"Quaderni ACP","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70772039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.53141/qacp.2022.242-247
Melodie O. Aricò, Emanuela Birocchi, Désirée Caselli
Antimicrobial resistance is a public health problem emerging in all areas of the world, making difficult to treat many common infections. Antimicrobial stewardship is an instrument to fight antimicrobial resistance. Antimicrobial stewardship is a set of procedures aimed at saving as many doses of antibiotics as possible to preserve their future efficacy, limiting the selective pressure on world microbial population. It includes those assessments regarding the administration of antibiotics that start from the correct patient’s selection to start antibiotic treatment, to choose the most suitable molecule and the route of administration, collecting microbiological samples to isolate a microorganism and arrive at any modification of narrow-spectrum antibiotic therapy or even discontinuation of the antibiotic.
{"title":"Uso appropriato degli antibiotici e stewardship in pediatria","authors":"Melodie O. Aricò, Emanuela Birocchi, Désirée Caselli","doi":"10.53141/qacp.2022.242-247","DOIUrl":"https://doi.org/10.53141/qacp.2022.242-247","url":null,"abstract":"Antimicrobial resistance is a public health problem emerging in all areas of the world, making difficult to treat many common infections. Antimicrobial stewardship is an instrument to fight antimicrobial resistance. Antimicrobial stewardship is a set of procedures aimed at saving as many doses of antibiotics as possible to preserve their future efficacy, limiting the selective pressure on world microbial population. It includes those assessments regarding the administration of antibiotics that start from the correct patient’s selection to start antibiotic treatment, to choose the most suitable molecule and the route of administration, collecting microbiological samples to isolate a microorganism and arrive at any modification of narrow-spectrum antibiotic therapy or even discontinuation of the antibiotic.","PeriodicalId":39791,"journal":{"name":"Quaderni ACP","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70772451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.53141/qacp.2022.100-104
G. Toffol, R. Buzzetti, L. Reali
{"title":"Covid-19 nelle cure primarie pediatriche in Italia, uno studio osservazionale (2° parte)","authors":"G. Toffol, R. Buzzetti, L. Reali","doi":"10.53141/qacp.2022.100-104","DOIUrl":"https://doi.org/10.53141/qacp.2022.100-104","url":null,"abstract":"","PeriodicalId":39791,"journal":{"name":"Quaderni ACP","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70771123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.53141/qacp.2022.128-132
F. Orlando, Germana Nardini, Daniele De Brasi
Autoinflammatory diseases (AIDs) are a family of rare medical entities, characterized by sterile systemic inflammatory episodes caused by exaggerated activation of the innate immune system, for which the pathogenic role of autoantibodies, B or T cells is less relevant. During the past 20 years, a growing number of monogenic inflammatory diseases have been described and their respective responsible genes identified. Proteins encoded by these genes are involved in the regulatory pathways of inflammation and they are mostly expressed in cells of the innate immune system. Since symptoms can overlap within this rapidly expanding disease category, accurate genetic diagnosis is extremely important to start early targeted treatment and to prevent clinically significant or life-threatening complications. On the other hand, detection of more and more genetic variants makes interpretation of results more complicated, and often a genetic diagnosis is not achieved. Thus, the clinical picture represents the starting point for establishing an effective therapy when genetic data are not sufficient or inconclusive. Biologic agents blocking cytokines action have proved to be dramatically effective in a lot of patients.
{"title":"Le malattie autoinfiammatorie: aspetti patogenetici e clinici (Prima parte)","authors":"F. Orlando, Germana Nardini, Daniele De Brasi","doi":"10.53141/qacp.2022.128-132","DOIUrl":"https://doi.org/10.53141/qacp.2022.128-132","url":null,"abstract":"Autoinflammatory diseases (AIDs) are a family of rare medical entities, characterized by sterile systemic inflammatory episodes caused by exaggerated activation of the innate immune system, for which the pathogenic role of autoantibodies, B or T cells is less relevant. During the past 20 years, a growing number of monogenic inflammatory diseases have been described and their respective responsible genes identified. Proteins encoded by these genes are involved in the regulatory pathways of inflammation and they are mostly expressed in cells of the innate immune system. Since symptoms can overlap within this rapidly expanding disease category, accurate genetic diagnosis is extremely important to start early targeted treatment and to prevent clinically significant or life-threatening complications. On the other hand, detection of more and more genetic variants makes interpretation of results more complicated, and often a genetic diagnosis is not achieved. Thus, the clinical picture represents the starting point for establishing an effective therapy when genetic data are not sufficient or inconclusive. Biologic agents blocking cytokines action have proved to be dramatically effective in a lot of patients.","PeriodicalId":39791,"journal":{"name":"Quaderni ACP","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70771858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.53141/qacp.2022.170-173
A. Pepe, Angelo Colucci, Lucia Nazzaro
DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is a complex and potentially life-threatening drug induced hypersensitivity reaction. It is characterized by a massive skin reaction associated with multiorgan involvement, lymphadenopathy, eosinophilia. Here we describe a case of DRESS syndrome with acute liver failure in an 11-year-old boy triggered by Valproic Acid. We emphasize the importance of differential diagnosis on the basis of clinical, anamnestic and laboratory data.
{"title":"La complessità della diagnosi di una sindrome da reazione a farmaco nel bambino","authors":"A. Pepe, Angelo Colucci, Lucia Nazzaro","doi":"10.53141/qacp.2022.170-173","DOIUrl":"https://doi.org/10.53141/qacp.2022.170-173","url":null,"abstract":"DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is a complex and potentially life-threatening drug induced hypersensitivity reaction. It is characterized by a massive skin reaction associated with multiorgan involvement, lymphadenopathy, eosinophilia. Here we describe a case of DRESS syndrome with acute liver failure in an 11-year-old boy triggered by Valproic Acid. We emphasize the importance of differential diagnosis on the basis of clinical, anamnestic and laboratory data.","PeriodicalId":39791,"journal":{"name":"Quaderni ACP","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70771908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.53141/qacp.2022.153-156
Addarii Francesca, Elisabetta Ciracò, Ketty Polo
L’epidemia da Covid-19 ha alterato significativamente l’apprendimento e lo sviluppo nei bambini in età scolare. Lo studio intende esplorare le funzioni esecutive prima e dopo la quarantena, indagando il possibile effetto di un intervento di un laboratorio di scacchi. Sono stati coinvolti 83 bambini: 39 (gruppo controllo-GC) hanno svolto le attività scolastiche in didattica a distanza; 44 (gruppo sperimentale-GS) hanno svolto didattica a distanza e un laboratorio di scacchi online. I genitori hanno compilato il questionario BRIEF per la valutazione delle funzioni esecutive prima dell’attivazione del laboratorio (marzo 2020) e al termine dell’anno scolastico (giugno 2020). I risultati evidenziano nel GC un aumento della frequenza di rischio nell’acquisizione delle funzioni esecutive (monitoraggio del compito, inibizione e regolazione comportamentale); al contrario, tali aree risultano migliorate nel GS. I risultati sostengono il laboratorio scacchi come utile strumento di supporto all’apprendimento e allo sviluppo di alcune funzioni esecutive.
{"title":"Scacchi a scuola, funzioni esecutive e pandemia: uno studio esplorativo","authors":"Addarii Francesca, Elisabetta Ciracò, Ketty Polo","doi":"10.53141/qacp.2022.153-156","DOIUrl":"https://doi.org/10.53141/qacp.2022.153-156","url":null,"abstract":"L’epidemia da Covid-19 ha alterato significativamente l’apprendimento e lo sviluppo nei bambini in età scolare. Lo studio intende esplorare le funzioni esecutive prima e dopo la quarantena, indagando il possibile effetto di un intervento di un laboratorio di scacchi. Sono stati coinvolti 83 bambini: 39 (gruppo controllo-GC) hanno svolto le attività scolastiche in didattica a distanza; 44 (gruppo sperimentale-GS) hanno svolto didattica a distanza e un laboratorio di scacchi online. I genitori hanno compilato il questionario BRIEF per la valutazione delle funzioni esecutive prima dell’attivazione del laboratorio (marzo 2020) e al termine dell’anno scolastico (giugno 2020). I risultati evidenziano nel GC un aumento della frequenza di rischio nell’acquisizione delle funzioni esecutive (monitoraggio del compito, inibizione e regolazione comportamentale); al contrario, tali aree risultano migliorate nel GS. I risultati sostengono il laboratorio scacchi come utile strumento di supporto all’apprendimento e allo sviluppo di alcune funzioni esecutive.","PeriodicalId":39791,"journal":{"name":"Quaderni ACP","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70771424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.53141/qacp.2022.10-16
C. Guardo, Marta Arrigoni, P. Santuz, Giovanna La Fauci
Anaphylaxis is a severe, potentially life-threatening systemic hypersensitivity reaction. Despite the global incidence shows an increasing trend for anaphylaxis, few cases appear to be promptly recognized and correctly managed, showing a significant underuse of epinephrine injections. The most recent state of the art highlights the need for unanimously accepted diagnostic criteria and the essential role of intramuscular epinephrine as the only first-line treatment when a patient is experiencing an acute anaphylactic reaction. On the other hand, evidence emphasize that glucocorticoids have a limited role in the acute management of anaphylaxis and support the use of antihistamines with the only aim to relieve cutaneous symptoms. This review aims to present the latest guidelines concerning management and therapeutic approach to anaphylaxis in the Emergency Department, with a practical slant, underlying the utmost importance of epinephrine administration both in a domestic and hospital setting.
{"title":"Anafilassi: riconoscimento e gestione in pronto soccorso pediatrico","authors":"C. Guardo, Marta Arrigoni, P. Santuz, Giovanna La Fauci","doi":"10.53141/qacp.2022.10-16","DOIUrl":"https://doi.org/10.53141/qacp.2022.10-16","url":null,"abstract":"Anaphylaxis is a severe, potentially life-threatening systemic hypersensitivity reaction. Despite the global incidence shows an increasing trend for anaphylaxis, few cases appear to be promptly recognized and correctly managed, showing a significant underuse of epinephrine injections. The most recent state of the art highlights the need for unanimously accepted diagnostic criteria and the essential role of intramuscular epinephrine as the only first-line treatment when a patient is experiencing an acute anaphylactic reaction. On the other hand, evidence emphasize that glucocorticoids have a limited role in the acute management of anaphylaxis and support the use of antihistamines with the only aim to relieve cutaneous symptoms. This review aims to present the latest guidelines concerning management and therapeutic approach to anaphylaxis in the Emergency Department, with a practical slant, underlying the utmost importance of epinephrine administration both in a domestic and hospital setting.","PeriodicalId":39791,"journal":{"name":"Quaderni ACP","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70771379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.53141/qacp.2022.157-159
M. G. Gleijeses, Francesca Annunziata, F. Silvestri
{"title":"Scacchi a scuola, funzioni esecutive e pandemia: uno studio esplorativo","authors":"M. G. Gleijeses, Francesca Annunziata, F. Silvestri","doi":"10.53141/qacp.2022.157-159","DOIUrl":"https://doi.org/10.53141/qacp.2022.157-159","url":null,"abstract":"","PeriodicalId":39791,"journal":{"name":"Quaderni ACP","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70771517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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