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A Study on Enumeration of Factors Prone to the Development of COVID-19-Associated Mucormycosis 新型冠状病毒相关毛霉病易发因素的枚举研究
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-06-19 DOI: 10.1055/s-0043-1769582
S. Velusamy, Jayakumar Rajagopal, Jessica Jayakumar, Dharshini Parthiban, Adeeb Ismail Zahir Hussain
Abstract Background  Patients with pre-existing chronic medical conditions with altered immunity are prone to COVID-19-associated mucormycosis (CAM). Objective  In this study, our objectives were to identify the risk factors that increase the chances of developing CAM and to determine the severity of the risk factors of CAM. Thereby, we can optimize the modifiable risk factors for developing CAM in coronavirus disease 2019 (COVID-19) patients. For instance, better control of blood glucose levels in COVID-19 patients can decrease the risk of developing CAM. Materials and Methods  The data was collected retrospectively from 1000 COVID-19 infected patients, above the age of 18 years during the time period of March 2021 to August 2021, in which 86 patients had confirmed CAM. Statistical Analysis  Binary logistic regression and curve estimation analysis were performed using SPSS software version 29 for identifying the associated risk factors of CAM with the significance of p -value less than 0.05. Results  Factors such as severe inflammation ( p  = 0.048), high dose of steroid administration ( p  = 0.005), increasing age ( p  < 0.001), and prolonged hospital stay ( p  < 0.001) were statistically proven to be significant risk factors, associated with CAM. Conclusion  Increasing age, severe inflammation, high dose of steroid administration, and prolonged hospital stay have association with occurrence of CAM.
摘要背景 已有慢性疾病且免疫力改变的患者容易患上新冠肺炎相关毛霉菌病(CAM)。客观的 在这项研究中,我们的目标是确定增加患CAM几率的风险因素,并确定CAM风险因素的严重程度。因此,我们可以优化2019冠状病毒病(新冠肺炎)患者发展CAM的可改变风险因素。例如,更好地控制新冠肺炎患者的血糖水平可以降低患CAM的风险。材料和方法 数据是从2021年3月至2021年8月期间1000名18岁以上的新冠肺炎感染患者中收集的,其中86名患者已确诊CAM。统计分析 使用SPSS软件29版进行二元逻辑回归和曲线估计分析,以确定CAM的相关危险因素,p值的显著性小于0.05。后果 严重炎症等因素(p = 0.048),高剂量类固醇给药(p = 0.005),年龄增加(p < 0.001)和住院时间延长(p < 0.001)在统计学上被证明是与CAM相关的显著风险因素。结论 年龄增长、严重炎症、高剂量类固醇给药和住院时间延长与CAM的发生有关。
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引用次数: 0
Mucormycosis of the Middle Ear—A Report of a Rare Case 中耳毛霉菌病——一例罕见病例报告
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-06-19 DOI: 10.1055/s-0043-1769583
Megha Madhu, S. Kamath P, V. Bhat, T. Srinivas
Abstract Mucormycosis is an opportunistic fungal infection that often affects the nose and paranasal sinuses. The disease prevalence was very high in India during the coronavirus disease 2019 pandemic, thereby raising public awareness about this disease. The general practitioners were updated about the disease characteristics and the requirement for emergency management. Yet, in some instances, the treatment was inadequate due to delayed presentation and low affordability for treatment. The mucormycosis of the ear, on the other hand, is a rare occurrence that demands meticulous study for early diagnosis and management. Here, we discuss the case of a patient with mucormycosis of the middle ear.
摘要毛霉菌病是一种机会性真菌感染,经常影响鼻子和鼻窦。在2019冠状病毒病大流行期间,印度的疾病流行率非常高,从而提高了公众对这种疾病的认识。向全科医生介绍了疾病特征和应急管理要求的最新情况。然而,在某些情况下,由于就诊延迟和治疗费用低,治疗不充分。另一方面,耳朵毛霉菌病是一种罕见的疾病,需要仔细研究以进行早期诊断和治疗。在这里,我们讨论一例中耳毛霉菌病患者。
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引用次数: 0
A Study to Assess the Knowledge and Practice of Parents Regarding Home Management of Minor Ailments in Children Visiting Tertiary Care Hospital Mangaluru 芒格鲁鲁三级医院小病患儿家长家庭管理知识与实践评估
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-06-19 DOI: 10.1055/s-0043-1770071
Navitha K., Melba Roshini Lobo, U. J
Abstract Background  The nation's future depends on its children. Minor illnesses are a common occurrence during childhood. It is crucial to evaluate parents' knowledge and practice when it comes to dealing with minor illnesses. This study aimed to assess the knowledge and practice of parents regarding home management of minor ailments in children. Methods  The descriptive research design was adopted for this study. The sample consisted of 65 parents of under-5 children The sample was selected on the basis of the purposive sampling technique. Data was collected using a knowledge questionnaire and practice checklist related to the management of minor illnesses in children including fever, upper respiratory tract infection (URTI; cough, cold, sore throat), diarrhea, vomiting, abdominal colic, and superficial wound. Data collected from the subjects were analyzed by descriptive and inferential statistics. Results  Study revealed that 80% had good knowledge, 20% had moderate knowledge, and none of them had poor knowledge on home management of minor ailments. In terms of practice, 55.4% of parents had moderate practice in the management of fever, 93.8% had good practice regarding the management of URTI, 43.1% had a good practice in managing diarrhea at home, 47.7% of parents had poor practice regarding home management of abdomen colic, 56.9% parents had a good practice on management of vomiting at home, and 92.3% had good practice score on managing superficial wounds at home. There was a significant association found with education status and knowledge score, as well as educational status and occupation with URTI practice and source of health information with fever at p -value less than 0.05 level of significance. Conclusion  The results of this study showed that parents of under-5 children had good knowledge and practice regarding home management of minor ailments.
国家的未来取决于孩子们。小病在儿童时期很常见。当涉及到处理小病时,评估父母的知识和实践是至关重要的。本研究旨在评估家长对儿童小病家庭管理的知识和实践。方法采用描述性研究设计。样本由65名5岁以下儿童的父母组成,样本采用有目的抽样技术。使用知识问卷和实践清单收集数据,涉及儿童小病的管理,包括发烧、上呼吸道感染(URTI;咳嗽、感冒、喉咙痛、腹泻、呕吐、腹部绞痛和浅表伤口。从受试者收集的数据通过描述性和推断性统计进行分析。结果调查显示,80%的受访家庭对小病家庭护理知识有较好的认识,20%的受访家庭对小病家庭护理知识有中等程度的认识。在实践方面,55.4%的家长对发热的管理实践一般,93.8%的家长对尿路感染的管理实践良好,43.1%的家长对腹泻的家庭管理实践良好,47.7%的家长对腹部绞痛的家庭管理实践不佳,56.9%的家长对呕吐的家庭管理实践良好,92.3%的家长对浅表伤口的家庭管理实践良好。学历、职业与URTI执业、健康信息来源有显著相关,p值均小于0.05。结论5岁以下儿童家长对小病的家庭管理有较好的认识和实践。
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引用次数: 0
Prevalence and Characterization of Legionella pneumophila and Related Species from Water-Based Recreational Sites 水源性休闲场所嗜肺军团菌及其相关物种的流行情况和特征
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-06-19 DOI: 10.1055/s-0043-1770070
Sneha B Shetty, A. Kenjar, J. Raj, Akhila D.S, I. Karunasagar, R. Vittal
Abstract Background and Objectives   Legionella is a genus of gram-negative bacteria common in soil and aquatic systems and is associated with protists. They have emerged as a pathogenic group due to the increased use and poor maintenance of artificial water environments. This study aims at phenotypic and molecular identification of Legionella in water and swab samples collected from water-based recreational sites. The biofilm-forming ability of Legionella on exposure to various temperatures and iron concentrations was also studied. Methods  A total of 60 samples including 30 swab samples and 30 water samples (decorative fountain ponds, swimming pools, garden sprinklers, drip irrigation system) were collected from in and around Mangalore, Karnataka, India. From each source, swab and water samples were collected as per the Indian standard IS: 1622. The collected samples were processed within 4 hours of collection. The samples were subjected to microbiological and chemical estimation followed by filtration through a 0.2 µm membrane filter. Isolation of Legionella from collected samples was performed as per US Centers for Disease Control and Prevention guidelines 2005. The positive isolates were then checked for biofilm-forming ability at various temperatures (25°C, 35°C, and 45°C) and iron concentration (3 mg/L, 30 mg/L, and 300 mg/L) using crystal violet assay. Results  Out of 30, water and swab samples tested, one water sample from a garden sprinkler, swimming pool, and one from both water and swab samples from a decorative fountain showed the presence of Legionella . A biofilm study of Legionella at various temperatures and iron concentrations categorized the bacteria as a moderate biofilm former. Conclusion  This study revealed that most of the water and swab samples were found to be negative for Legionella that is quite encouraging and the contamination of water systems in recreational facilities can be reduced by decontamination techniques and proper hygienic practices.
背景与目的军团菌是一种常见于土壤和水生系统的革兰氏阴性菌属,与原生生物有关。由于人工水环境的使用增加和维护不善,它们已成为一种致病群体。本研究旨在研究从水上娱乐场所采集的水和拭子样本中军团菌的表型和分子鉴定。研究了军团菌在不同温度和铁浓度下的生物膜形成能力。方法在印度卡纳塔克邦芒格洛尔及其周边地区采集60份样本,包括30份拭子样本和30份水样(装饰性喷泉池、游泳池、花园洒水器、滴灌系统)。根据印度标准IS: 1622从每个来源收集棉签和水样。采集的样品在采集后4小时内处理。样品经过微生物学和化学评价,然后通过0.2µm膜过滤器过滤。按照2005年美国疾病控制和预防中心指南从收集的样本中分离军团菌。在不同温度(25°C、35°C和45°C)和铁浓度(3 mg/L、30 mg/L和300 mg/L)下,采用结晶紫法检测阳性分离株的生物膜形成能力。结果在30份水和棉签样本中,一个花园洒水器和游泳池的水样本和一个装饰喷泉的水和棉签样本均检测到军团菌。军团菌在不同温度和铁浓度下的生物膜研究将细菌归类为中等生物膜前体。结论本研究显示,大部分水和拭子样本对军团菌呈阴性,这是非常令人鼓舞的,通过净化技术和适当的卫生习惯可以减少娱乐设施水系统的污染。
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引用次数: 0
Utility of Hematological Parameters in Early Diagnosis of Neonatal Sepsis in Comparison to C-Reactive Protein 血液学参数在新生儿败血症早期诊断中的作用与C反应蛋白的比较
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-06-19 DOI: 10.1055/s-0043-1768593
D. Joshi, S. Padma, J. K., Shreya Goel, Abena Hidangmayum
Abstract Background  Neonatal sepsis is the most common cause of neonatal mortality and morbidity. As neonatal sepsis presents with subtle symptoms and signs, decision to start empirical antibiotics is most often based on risk profile. Hematological parameters and C-reactive protein (CRP) are routinely done as a part of sepsis screening, but isolation of microorganism on blood culture is the gold standard for diagnosis of sepsis. Methodology  One-hundred neonates with suspected sepsis were studied and their hematological parameters, hematological scoring system (HSS), and CRP were correlated to blood culture. Results  Among the study population, immature to total neutrophil count (I:T) ratio had the best sensitivity (94.1%) and negative predictive value (83.3%), followed by HSS with a sensitivity of 64.7% and negative predictive value of 68.4%, whereas CRP was more specific (75.9%). Conclusion  HSS and CRP are good predictors of diagnosis of neonatal sepsis. I:T ratio had the best sensitivity and negative predictive value.
摘要背景 新生儿败血症是导致新生儿死亡和发病的最常见原因。由于新生儿败血症表现出微妙的症状和体征,开始使用经验性抗生素的决定通常是基于风险状况。血液学参数和C反应蛋白(CRP)是败血症筛查的一部分,但在血液培养中分离微生物是诊断败血症的金标准。方法论 对100例疑似败血症新生儿进行了研究,并将其血液学参数、血液学评分系统(HSS)和CRP与血液培养相关。后果 在研究人群中,未成熟中性粒细胞与总中性粒细胞计数(I:T)的比率具有最佳的敏感性(94.1%)和阴性预测值(83.3%),其次是HSS,敏感性为64.7%,阴性预测值为68.4%,而CRP更具特异性(75.9%) HSS和CRP是诊断新生儿败血症的良好预测指标。I: T比值具有最佳的敏感性和阴性预测值。
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引用次数: 0
In Silico ADMET and Molecular Interaction Profiles of Phytochemicals from Medicinal Plants in Dakshina Kannada Dakshina Kannada药用植物化学物质的分子相互作用及ADMET分析
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-06-19 DOI: 10.1055/s-0043-1770057
J. James, Puneeth Deepak Ail, Lenisha Crasta, Rakshith Sudheer Kamath, M. H. Shura, S. T.J
Abstract The success or failure of a potential drug depends on its absorption, distribution, metabolism, excretion and toxicity (ADMET) characteristics, and these features are usually rate-limiting in the drug development process. Hence, it is essential to know about the predicted ADMET properties of the most promising leads to avoid the risk of late-stage attrition. This project focuses on in silico screening of ADMET properties of phytochemicals found in Dakshina Kannada's medicinal plants, which include Tinospora cordifolia , Azadirachta indica , Ocimum sanctum, and Plectranthus amboinicus , mainly known for their antimicrobial properties. The physicochemical properties, bioactivity scores, ADMET, and molecular interactions of the selected phytoconstituents were determined by QikProp, Molinspiration, ADMETlab 2.0, ProTox-II, and GLIDE. In addition, molecular docking checked for their binding interactions with target proteins 1JIJ and 4 HOE of Staphylococcus aureus and Candida albicans , respectively, as they were well known for their antimicrobial properties. In this studies, rosmarinic acid was well interacted phytochemical with both target proteins and has highest docking score. The physicochemical properties showed that all compounds fell under the recommended molecular weight, volume, and polar surface area range. Xanosporic acid violated two rules of Lipinski's Rule of Five, indicating that it may have problems with oral bioavailability. The ADME properties for most of the phytocompounds were within the recommended ranges; hence, they are promising candidates for drug development. Most phytoconstituents showed good bioactivity scores, indicating they have good druglikeness properties. On the analysis of the toxicity, most of the phytoconstituents were found to be noncarcinogenic and nonmutagenic. Therefore, this data can further be utilized as primary tools for determining the biological actions of these plants. Xanosporic acid was found to violate two out of three rules of Lipinski. Similarly, ursolic acid and oleanolic acid also showed a few undesirable properties. All other compounds otherwise showed desirable properties and hence are promising candidates for drug development. This data can be further utilized as primary tool for determining the biological actions of the plants.
一种潜在药物的成功或失败取决于其吸收、分布、代谢、排泄和毒性(ADMET)特征,而这些特征通常是药物开发过程中的限速因素。因此,有必要了解最有希望的线索的预测ADMET特性,以避免后期磨损的风险。本项目重点对Dakshina Kannada药用植物(包括Tinospora cordifolia、Azadirachta indica、Ocimum sanctum和Plectranthus amboinicus)中发现的植物化学物质进行ADMET特性的计算机筛选,这些植物主要以抗菌特性而闻名。采用QikProp、Molinspiration、ADMETlab 2.0、ProTox-II和GLIDE等软件测定所选植物成分的理化性质、生物活性评分、ADMET和分子相互作用。此外,分子对接检查了它们分别与金黄色葡萄球菌和白色念珠菌的靶蛋白1JIJ和4hoe的结合相互作用,因为它们具有众所周知的抗菌特性。在本研究中,迷迭香酸与两种靶蛋白均具有良好的植物化学相互作用,且对接得分最高。理化性质表明,所有化合物均在推荐的分子量、体积和极性表面积范围内。Xanosporic acid违反了Lipinski's Rule of Five的两条规则,表明它可能存在口服生物利用度问题。大多数植物化合物的ADME性能在推荐范围内;因此,它们是药物开发的有希望的候选者。大多数植物成分具有良好的生物活性,表明其具有良好的药物相似性。在毒性分析中,发现大部分植物成分无致癌性和非诱变性。因此,这些数据可以进一步用作确定这些植物生物作用的主要工具。黄孢菌酸被发现违反了利平斯基的三条规则中的两条。同样,熊果酸和齐墩果酸也表现出一些不良性质。所有其他化合物都显示出理想的特性,因此是药物开发的有希望的候选者。这些数据可以进一步用作确定植物生物作用的主要工具。
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引用次数: 1
Efficacy of Communication Skill Training on Knowledge and Skill of Nursing Students in Conveying Diagnosis to Patients with Cancer: A Pilot Study Approach 沟通技巧训练对护生向癌症患者传达诊断知识和技能的效果:一项初步研究方法
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-06-16 DOI: 10.1055/s-0043-1769581
Viji Prasad, P. Naik, Alphonsa Ancheril
Abstract Introduction  Procuring communication skills that enable nurses to be effective yet person-centeredness is increasingly a hallmark of quality cancer care. The growing importance of patient outcomes and experiences in health care may mean that communication skill training is finally getting the attention it so clearly deserves. Objectives  The main objectives of the study were to assess the efficacy of communication skill training on knowledge and skills of nursing students in conveying diagnosis to patients with cancer. Materials and Methods  Quasi-experimental pretest–posttest with control group research design was adopted for the study. A total of 32 third-year BSc nursing students (intervention group, 16; control group, 16) were selected by nonprobability purposive sampling technique from two selected colleges at Mangaluru. Baseline proforma, self-administered knowledge questionnaire, and breaking bad news assessment schedule were used for data collection. Tools were validated by 11 subject experts. Communication skill training was provided for 8 hours (2 hours of theory and 6 hours of skill training on conveying diagnosis). A blinding method was adopted to assess the skill of the students that enable to avoid subjectivity. Results  The mean age of participants in the intervention group was 20.56 and of participants in the control group was 20.94. All participants (100%) of both the intervention and control groups were females. The results showed there was a significant difference found in knowledge scores ( t  = 8.52, p  = 0.000) between the intervention and control groups after the intervention. There was a significant improvement found in conveying diagnosis skills among students between the intervention and control groups in different time periods. There was a slight positive correlation found between pretest knowledge scores and eliciting concerns domain of conveying diagnosis skill ( r  = 0.57, p  = 0.023). Conclusion  The study results revealed that communication skill training session was very effective for improving the knowledge and skills of students, and it enables them in providing quality care to patients with cancer through effective communication.
摘要简介 培养沟通技巧,使护士既有效又以人为本,这越来越成为癌症优质护理的标志。患者在医疗保健中的结果和经验越来越重要,这可能意味着沟通技能培训终于得到了应有的关注。目标 本研究的主要目的是评估沟通技能培训对护理学生向癌症患者传达诊断的知识和技能的有效性。材料和方法 本研究采用准实验前测-后测对照组研究设计。通过非概率目的抽样技术,从曼加卢鲁的两所大学中选择了32名三年级理学学士护理专业的学生(干预组,16名;对照组,16人)。采用基线形式表、自填知识问卷和突发坏消息评估表进行数据收集。11位主题专家对工具进行了验证。为8人提供了沟通技能培训 小时(2 理论课时和6 传达诊断的技能培训小时数)。采用盲法评估学生的技能,以避免主观性。后果 干预组参与者的平均年龄为20.56岁,对照组参与者的年龄为20.94岁。干预组和对照组的所有参与者(100%)均为女性。结果表明,学生的知识得分存在显著差异(t = 8.52,p = 0.000)。在不同时间段,干预组和对照组的学生在传达诊断技能方面有显著改善。预测知识得分与诊断技能表达的引发关注域之间存在轻微的正相关(r = 0.57,p = 0.023)。结论 研究结果表明,沟通技能培训课程对提高学生的知识和技能非常有效,使他们能够通过有效的沟通为癌症患者提供优质的护理。
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引用次数: 0
Restraints Practices on Patients of the Psychiatric Wards in a Selected Hospital, Mangalore 芒格洛尔一所选定医院精神科病房患者的限制措施
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-06-16 DOI: 10.1055/s-0043-1769580
C. Jayaprakash, S. Sequera, Chanu Battacharya
Abstract Background  Restraints are one of the common procedures performed in various medical settings, especially intensive care units, and psychiatric wards. There are various forms of restraints, including chemical, physical, and mixed restraints. The primary reasons for using restraints are to prevent injury to the patient and others, and to reduce violent behavior in psychotic patients. Objectives  The aim of this article was to identify the types of restraints used for psychiatric patients and current restraint practices for patients in psychiatric wards of selected mental health facilities. Methods  This was a descriptive cross-sectional study conducted among 100 psychiatric patients selected using purposive sampling techniques. An observational checklist was used to assess restraint practice in patients who met study criteria. Results  The majority of patients (44%) received chemical restraints, some (28%) received physical restraints, but a minority (28%) used mixed restraints. In terms of practice, most patients (91%) received reasonably safe restraint care. An association was found between practice of restraints and restraints type with a p -value (0.001) less than 0.05 at a significance level of 0.05. Conclusions  The development of mandatory practice protocols is critical for better nursing care.
摘要背景 约束是在各种医疗环境中执行的常见程序之一,尤其是重症监护室和精神病病房。有各种形式的约束,包括化学约束、物理约束和混合约束。使用约束的主要原因是防止对患者和他人造成伤害,并减少精神病患者的暴力行为。目标 本文的目的是确定用于精神病患者的约束类型,以及选定精神卫生机构精神病房中患者的当前约束做法。方法 这是一项描述性的横断面研究,使用有目的的抽样技术对100名精神病患者进行了选择。观察检查表用于评估符合研究标准的患者的约束实践。后果 大多数患者(44%)接受了化学约束,一些患者(28%)接受了物理约束,但少数患者(28%的患者)使用了混合约束。就实践而言,大多数患者(91%)接受了合理安全的约束护理。在约束实践和约束类型之间发现了相关性,p值(0.001)小于0.05,显著性水平为0.05。结论 强制性实践规程的制定对于更好的护理至关重要。
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引用次数: 0
Effect of Multimodal Intervention on Cancer-Related Fatigue and Quality of Life among Patients Undergoing Cancer Treatment—Pilot Study (Part 1) 多模式干预对癌症治疗患者癌症相关疲劳和生活质量的影响——初步研究(上)
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-06-16 DOI: 10.1055/s-0043-1768592
Shambhavi Shambhavi, D. Lobo
Abstract Background  Cancer-related fatigue (CRF) is the most common and devastating problem in cancer patients even after successful treatment. CRF has a severe impact on daily activities, social relationships, reintegration, and overall quality of life (QOL). Objective  This study was done to evaluate the effect of multimodal intervention (MMI) on CRF and QOL among cancer patients undergoing cancer treatment. Materials and Methods  One group before-and-after study (pre-experimental design) was conducted among cancer patients undergoing cancer treatment who met inclusion criteria and were selected using a purposive sampling technique, in selected hospitals. MMI consisted of exercise program, acupressure, and home care management guide. Pre-test CRF and QOL were assessed on first day using a FACIT-F scale (Functional Assessment of Chronic Illness Therapy: Fatigue) and Functional Assessment of Cancer Therapy: Fatigue (FACT-G) Version 4, respectively. Post- test for CRF was further determined after 7 days, 21 days, and 3months and QOL was determined after 21 days and 3 months. Statistical Analysis  Demographic and clinical characteristics of the participants are presented as frequency and percentage. Comparison of pre- test and post-test means of CRF and QOL is done by repeated measures analysis of variance (ANOVA). Correlation between fatigue and QOL of cancer patients was found by using Pearson correlation test. Results  The mean pre-test fatigue score of the cancer patients (pre-test mean= 25.21) was lower than their mean post-test fatigue scores (post-test 1 =25.83, post-test 2 = 28.28, and post-test 3 = 34.72). There was a significant difference in CRF and QOL scores between before and after the MMI. In the repeated measures ANOVA, p -value is less than 0.05 (level of significance p  < 0.05). Conclusion  Regardless of mechanism of occurrence of fatigue, most patients living with cancer suffer with persistent CRF. Yet it is often not assessed, has limited treatment options, there is a need to assess the state of fatigue in cancer patients. They do need intervention to reduce the fatigue and to improve the QOL. Nonpharmacological therapies are the best strategies to manage the fatigue among cancer patients without any safety issue.
摘要背景 癌症相关疲劳(CRF)是癌症患者中最常见和最具破坏性的问题,即使在成功治疗后也是如此。CRF对日常活动、社会关系、重新融入社会和整体生活质量(QOL)有严重影响。客观的 本研究旨在评估多模式干预(MMI)对接受癌症治疗的癌症患者CRF和生活质量的影响。材料和方法 一组研究前后(实验前设计)在接受癌症治疗的癌症患者中进行,这些患者符合入选标准,并在选定的医院使用有目的的抽样技术进行选择。MMI包括锻炼计划、穴位按摩和家庭护理管理指南。试验前CRF和QOL分别在第一天使用FACIT-F量表(慢性疾病治疗功能评估:疲劳)和癌症治疗功能评估(FACT-G)版本4进行评估。CRF试验后在7天、21天和3个月后进一步测定,生活质量在21天和三个月后测定。统计分析 参与者的人口统计学和临床特征以频率和百分比表示。通过重复测量方差分析(ANOVA)对CRF和生活质量的测试前和测试后均值进行比较。应用Pearson相关检验发现癌症患者疲劳与生活质量之间存在相关性。后果 癌症患者的平均测试前疲劳评分(测试前平均值=25.21)低于他们的平均测试后疲劳评分(试验后1=25.83,试验后2 = 28.28和测试后3 = 术前和术后CRF和QOL评分有显著性差异。在重复测量方差分析中,p值小于0.05(显著性水平p < 0.05)。结论 无论疲劳的发生机制如何,大多数癌症患者都患有持续性CRF。然而,它往往没有得到评估,治疗选择有限,有必要评估癌症患者的疲劳状态。他们确实需要干预来减少疲劳并提高生活质量。在没有任何安全问题的情况下,非药物疗法是治疗癌症患者疲劳的最佳策略。
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引用次数: 0
Quality of Life and Expressed Emotion in Caregivers of Patients with Psychiatric Disorders 精神病患者护理人员的生活质量和情绪表达
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-06-16 DOI: 10.1055/s-0043-1769578
Sabeena Mtp, Agnes Ej, Lavina Rodrigues
Abstract Background  Caregivers form an integral part of the psychosocial management of patients with psychiatric conditions. Caregivers of patients with major psychiatric disorders feel burdened, as these disorders are unpredictable and long lasting. The study was aimed to assess the quality of life (QOL) and expressed emotion among caregivers of patient's with psychiatric disorders. Materials and Methods  A cross-sectional descriptive design was adopted for the study. The sample consisted of 300 caregivers of psychiatric patients who visited psychiatric outpatient department and inpatient department of selected hospital. The caregivers were selected by using convenient sampling technique. Baseline proforma, the World Health Organization Quality of Life Scale (WHO QOL BREF), and Family Attitude Scale were used to collect the data. Results  Descriptive and inferential statistics were used to analyze the data. The analysis revealed that there was a weak negative correlation between QOL and expressed emotions. The obtained “ r” value (−0.14) was statistically not significant at 0.05 level of significance. Hence, the research hypothesis was rejected and the null hypothesis was accepted. Conclusion  The study concluded that there was a low negative correlation between QOL and expressed emotions. The obtained “ r ” value (−0.14) is statistically not significant at 0.05 level of significance. But there was association between QOL and income and occupation of the caregiver.
摘要背景 护理人员是精神病患者心理社会管理的组成部分。患有严重精神疾病的患者的护理人员感到负担沉重,因为这些疾病是不可预测的,而且会持续很长时间。该研究旨在评估精神障碍患者护理人员的生活质量(QOL)和情绪表达。材料和方法 本研究采用横断面描述性设计。样本包括300名精神病患者的护理人员,他们访问了选定医院的精神科门诊部和住院部。护理人员采用方便的抽样技术进行选择。采用基线量表、世界卫生组织生活质量量表(世界卫生组织QOL BREF)和家庭态度量表收集数据。后果 采用描述性和推断统计学方法对数据进行分析。分析显示,生活质量与表达的情绪之间存在微弱的负相关。所获得的“r”值(−0.14)在0.05的显著性水平上无统计学意义。因此,研究假设被拒绝,无效假设被接受。结论 研究得出结论,生活质量与表达的情绪之间存在较低的负相关。所获得的“r”值(−0.14)在0.05的显著性水平上无统计学意义。但生活质量和照顾者的收入和职业之间存在关联。
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Journal of Health and Allied Sciences NU
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