Abstract Objective This study was aimed at determining the nephroprotective potential of Sphaeranthus indicus Linn methanol extract (SME) against hyperglycemia and dyslipidemia in streptozotocin (STZ)-induced diabetic nephropathy (DNP) in adult Wistar albino rats. Materials and Methods Following STZ-induced diabetes, adult albino Wistar rats of either sex with serum glucose level more than 250 mg/dL were chosen and randomized into six groups ( n = 6 rats per group) and received the treatment as follows: Group I: Normal nondiabetic (ND) rats received a single intraperitoneal dose of citrate buffer in the same volume as STZ and 1% (w/v) carboxymethyl cellulose (CMC) per os (po), group II: diabetic (STZ) control rats received oral dosage of 1% (w/v) CMC, group III, IV and V: STZ + SME treated rats received a suspension of SME (100, 200, and 400 mg/kg, po) in 1% (w/v) CMC, and group VI: STZ + MET treated rats received metformin (500 mg/kg, po) as suspension in 1% (w/v) CMC. From 28th day to the 56th day of STZ injection, SME and MET were given for 28 days in the form of freshly prepared suspension. The impact of STZ-induced DNP was analyzed through the estimation of body weight, serum glucose, and hemoglobin A1c levels, renal functional parameters, the serum lipid profile, oxidative stress markers, and analysis of renal histoarchitecture. Result Diabetic (STZ) control rats showed significant alterations in body weight, serum glucose and hemoglobin A1c levels, renal functional parameters, the serum lipid profile, oxidative stress markers, and renal histoarchitecture in contrast to normal ND rats. SME and MET treatment significantly reduced hyperglycemia-induced enhanced lipid profile and oxidative stress, normalized renal functional parameters, and restored renal histoarchitecture by reducing vacuolar degeneration of renal tubules in contrast to diabetic (STZ) control rats. These findings were attributed to SME's efficacy in DNP. Conclusion In STZ-sensitized diabetic rats, SME retarded the progress of nephropathy. The observed nephroprotective potential of SME is ascribed to its hypoglycemic, hypolipidemic, and antioxidant activities.
{"title":"Nephroprotective Potential of Sphaeranthus indicus Linn Extract against Hyperglycemia and Dyslipidemia in Streptozotocin-Induced Diabetic Nephropathy","authors":"Vishalaxi Jadhav, J. Vaghela","doi":"10.1055/s-0043-1769511","DOIUrl":"https://doi.org/10.1055/s-0043-1769511","url":null,"abstract":"Abstract Objective This study was aimed at determining the nephroprotective potential of Sphaeranthus indicus Linn methanol extract (SME) against hyperglycemia and dyslipidemia in streptozotocin (STZ)-induced diabetic nephropathy (DNP) in adult Wistar albino rats. Materials and Methods Following STZ-induced diabetes, adult albino Wistar rats of either sex with serum glucose level more than 250 mg/dL were chosen and randomized into six groups ( n = 6 rats per group) and received the treatment as follows: Group I: Normal nondiabetic (ND) rats received a single intraperitoneal dose of citrate buffer in the same volume as STZ and 1% (w/v) carboxymethyl cellulose (CMC) per os (po), group II: diabetic (STZ) control rats received oral dosage of 1% (w/v) CMC, group III, IV and V: STZ + SME treated rats received a suspension of SME (100, 200, and 400 mg/kg, po) in 1% (w/v) CMC, and group VI: STZ + MET treated rats received metformin (500 mg/kg, po) as suspension in 1% (w/v) CMC. From 28th day to the 56th day of STZ injection, SME and MET were given for 28 days in the form of freshly prepared suspension. The impact of STZ-induced DNP was analyzed through the estimation of body weight, serum glucose, and hemoglobin A1c levels, renal functional parameters, the serum lipid profile, oxidative stress markers, and analysis of renal histoarchitecture. Result Diabetic (STZ) control rats showed significant alterations in body weight, serum glucose and hemoglobin A1c levels, renal functional parameters, the serum lipid profile, oxidative stress markers, and renal histoarchitecture in contrast to normal ND rats. SME and MET treatment significantly reduced hyperglycemia-induced enhanced lipid profile and oxidative stress, normalized renal functional parameters, and restored renal histoarchitecture by reducing vacuolar degeneration of renal tubules in contrast to diabetic (STZ) control rats. These findings were attributed to SME's efficacy in DNP. Conclusion In STZ-sensitized diabetic rats, SME retarded the progress of nephropathy. The observed nephroprotective potential of SME is ascribed to its hypoglycemic, hypolipidemic, and antioxidant activities.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57981204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Since the discovery of magnetic resonance imaging (MRI) as an imaging modality, it has evolved immensely and is still doing so. Most imaging modalities have made bedside or emergency imaging possible due to their portability. This aspect is yet to be fully evaluated and established in the case of MRI as its high-field strength requires specialized infrastructure and its time-consuming nature makes its portability questionable. The goal of this review is to access the efficiency and feasibility of low-field portable MRI (pMRI) systems in a wide array of health care applications. Articles from indexed journals, on PubMed, Springer, Elsevier, etc. databases, relevant to this study were searched and reviewed. This review provides an atypical design that could be used in making a pMRI unit that could find its potential in diagnosing a wide variety of pathologies with an added advantage of imaging critical patients in the intensive care unit or patients in isolation due to its portability, imaging patients with implants or prosthesis effectively due to its low field, pediatric imaging due to its high speed, for guided interventions, imaging obese and claustrophobic patients due to its open nature, in dental imaging, extremity scanning, etc. With its vast spectrum of applications in the health care system, the future of low-field pMRI units seems to be bright.
{"title":"The Rise and Efficiency of Low Field Portable MRI Scanners","authors":"T. Pires, Jaseemudheen M.M","doi":"10.1055/s-0043-1769759","DOIUrl":"https://doi.org/10.1055/s-0043-1769759","url":null,"abstract":"Abstract Since the discovery of magnetic resonance imaging (MRI) as an imaging modality, it has evolved immensely and is still doing so. Most imaging modalities have made bedside or emergency imaging possible due to their portability. This aspect is yet to be fully evaluated and established in the case of MRI as its high-field strength requires specialized infrastructure and its time-consuming nature makes its portability questionable. The goal of this review is to access the efficiency and feasibility of low-field portable MRI (pMRI) systems in a wide array of health care applications. Articles from indexed journals, on PubMed, Springer, Elsevier, etc. databases, relevant to this study were searched and reviewed. This review provides an atypical design that could be used in making a pMRI unit that could find its potential in diagnosing a wide variety of pathologies with an added advantage of imaging critical patients in the intensive care unit or patients in isolation due to its portability, imaging patients with implants or prosthesis effectively due to its low field, pediatric imaging due to its high speed, for guided interventions, imaging obese and claustrophobic patients due to its open nature, in dental imaging, extremity scanning, etc. With its vast spectrum of applications in the health care system, the future of low-field pMRI units seems to be bright.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42831820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Objectives The aim of this study was to determine the relationship between emotional intelligence, self-esteem, and empathy of nursing students undergoing clinical experience in pediatric units. Materials and Methods A cross-sectional survey was conducted and data were gathered from 60 BSc nursing students undergoing clinical experience in pediatric units. Self-report questionnaires assessing emotional intelligence, self-esteem, and empathy were used and information about demographic details was collected. Statistical Analysis Pearson's correlation was used to find relationship between the constructs. Results Nursing students had moderately high level of emotional intelligence. Nursing students had below average level of empathy. There was no significant relationship between emotional intelligence and empathy of nursing students. There was a significant positive relationship between emotional intelligence and self-esteem of nursing students. There was no significant relationship between empathy and self-esteem of nursing students. Conclusion More research needs to be conducted to find the relationship between emotional intelligence, self-esteem, and empathy of nursing students so that proper training measures can be adopted to enhance these qualities which are crucial in providing quality care to the patients.
{"title":"The Relationship between Emotional Intelligence, Self-Esteem, and Empathy among Nursing Students—A Pilot Study (Part 1)","authors":"P. S. Castelino, T. Mendonca","doi":"10.1055/s-0043-1769584","DOIUrl":"https://doi.org/10.1055/s-0043-1769584","url":null,"abstract":"Abstract Objectives The aim of this study was to determine the relationship between emotional intelligence, self-esteem, and empathy of nursing students undergoing clinical experience in pediatric units. Materials and Methods A cross-sectional survey was conducted and data were gathered from 60 BSc nursing students undergoing clinical experience in pediatric units. Self-report questionnaires assessing emotional intelligence, self-esteem, and empathy were used and information about demographic details was collected. Statistical Analysis Pearson's correlation was used to find relationship between the constructs. Results Nursing students had moderately high level of emotional intelligence. Nursing students had below average level of empathy. There was no significant relationship between emotional intelligence and empathy of nursing students. There was a significant positive relationship between emotional intelligence and self-esteem of nursing students. There was no significant relationship between empathy and self-esteem of nursing students. Conclusion More research needs to be conducted to find the relationship between emotional intelligence, self-esteem, and empathy of nursing students so that proper training measures can be adopted to enhance these qualities which are crucial in providing quality care to the patients.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42857108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Background Hospitalization with specialized medical care and equipment in neonatal intensive care unit (NICU) can help preterm infants survive and thrive; negatively it can lead to separation from the mother with an impact on their growth and behavior. It is critical to assess the interventions that are more beneficial for their development at this particular period. The study's objective was to examine the effectiveness of maternal-directed multisensory stimulation in premature neonates admitted to NICU on neonatal outcomes. Methods A pilot, quasi-experimental research was designed where 31mother-preterm newborn dyads were enrolled in the intervention and control group, respectively, using a purposive sampling technique. The study included medically stable preterm neonates admitted to NICU between 30 and 36 weeks of gestation weighing 1 to 2.5kg. The preterm in the study group was given ATVV (Auditory, Tactile, Vestibular, and Visual) stimulation for 10 days by the mother, whereas the preterm in the comparison group received the standard treatment. The neonatal outcomes evaluated were weight, physiological parameters, and behavioral assessment of preterm neonates. Results Preterm newborns who received the intervention scored significantly better than the comparison group on the parameters of heart and respiratory rate, blood oxygen levels, weight, and preterm assessment behavior between the 7th and 10th day of the intervention that suggests the effectiveness of the intervention in improving these parameters of preterm newborns. Conclusion Maternal guidance and participation in the care of a preterm newborn have a beneficial neonatal outcome in stabilizing the physiological parameters, and improving the weight and preterm infant behavioral characteristics.
{"title":"Maternal Participation in Sensory Care of Preemies: A Pilot Study Examining the Effect on Neonatal Outcome in NICU","authors":"R. Lobo, T. Mendonca","doi":"10.1055/s-0043-1769579","DOIUrl":"https://doi.org/10.1055/s-0043-1769579","url":null,"abstract":"Abstract Background Hospitalization with specialized medical care and equipment in neonatal intensive care unit (NICU) can help preterm infants survive and thrive; negatively it can lead to separation from the mother with an impact on their growth and behavior. It is critical to assess the interventions that are more beneficial for their development at this particular period. The study's objective was to examine the effectiveness of maternal-directed multisensory stimulation in premature neonates admitted to NICU on neonatal outcomes. Methods A pilot, quasi-experimental research was designed where 31mother-preterm newborn dyads were enrolled in the intervention and control group, respectively, using a purposive sampling technique. The study included medically stable preterm neonates admitted to NICU between 30 and 36 weeks of gestation weighing 1 to 2.5kg. The preterm in the study group was given ATVV (Auditory, Tactile, Vestibular, and Visual) stimulation for 10 days by the mother, whereas the preterm in the comparison group received the standard treatment. The neonatal outcomes evaluated were weight, physiological parameters, and behavioral assessment of preterm neonates. Results Preterm newborns who received the intervention scored significantly better than the comparison group on the parameters of heart and respiratory rate, blood oxygen levels, weight, and preterm assessment behavior between the 7th and 10th day of the intervention that suggests the effectiveness of the intervention in improving these parameters of preterm newborns. Conclusion Maternal guidance and participation in the care of a preterm newborn have a beneficial neonatal outcome in stabilizing the physiological parameters, and improving the weight and preterm infant behavioral characteristics.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46830443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Patients often report to dental practice with a wide range of chief complaints. At times, young adult patients, seemingly fit clinically, report extensively damaged dentition. It is important that such patients be evaluated more extensively and the etiology if any, for such debilitated dentition, must be assessed. Dental implants are a successful treatment modality that helps to restore the function and esthetics of a patient. Early dental implant failure refers to the dental implant's failure to osseointegrate with the native bone during the phase of healing. This article describes one such young adult patient of 34 years, who presented with a history of dental implant failures without any underlying systemic comorbidities. The patient's elaborate history was taken and it was found that the patient had a severe vitamin D deficiency. Following treatment of the deficiency, the case was managed effectively with the help of a maxillary cement-retained implant-supported full-arch fixed prosthesis and, an implant and tooth-supported mandibular cast partial denture.
{"title":"Extensive Rehabilitation of a Medically Compromised Patient with Vitamin-D Deficiency Using Dental Implants: A Case Report","authors":"M. K. Parakh, M. Shetty, R. Hegde, Athma Shetty","doi":"10.1055/s-0043-1768595","DOIUrl":"https://doi.org/10.1055/s-0043-1768595","url":null,"abstract":"Abstract Patients often report to dental practice with a wide range of chief complaints. At times, young adult patients, seemingly fit clinically, report extensively damaged dentition. It is important that such patients be evaluated more extensively and the etiology if any, for such debilitated dentition, must be assessed. Dental implants are a successful treatment modality that helps to restore the function and esthetics of a patient. Early dental implant failure refers to the dental implant's failure to osseointegrate with the native bone during the phase of healing. This article describes one such young adult patient of 34 years, who presented with a history of dental implant failures without any underlying systemic comorbidities. The patient's elaborate history was taken and it was found that the patient had a severe vitamin D deficiency. Following treatment of the deficiency, the case was managed effectively with the help of a maxillary cement-retained implant-supported full-arch fixed prosthesis and, an implant and tooth-supported mandibular cast partial denture.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42269542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Objectives Coronavirus disease 2019 (COVID-19) affects the respiratory system predominantly. However, post-COVID recovery, many manifested neurological and psychological symptoms, unrelated to the respiratory system. We aimed to estimate psychological impairment in individuals who were infected with COVID-19 in comparison with two uninfected control groups, and between different age cohorts. Materials and Methods We compared three groups with respect to COVID-19—those infected, those not infected but witness to someone infected, and those neither infected nor witness to anyone infected, along with age cohort comparison. The standard Depression, Anxiety and Stress Scale - 42 items (DASS 42) questionnaire, with additional questions were answered by 301 participants. Statistical Analysis SPSS was used for analyses, with Mann–Whitney U test, Kruskal–Wallis test, and Tukey's post hoc test. Results Significantly higher levels of depression, anxiety, and stress were found in the infected group than in the uninfected groups, and significant difference was found between the older age cohorts (50 and above) of each group. The percentages of the infected group with severe to very severe depression, anxiety, and stress were higher than the other groups. Conclusion There is greater psychological impairment in individuals post-COVID recovery, and there is higher impairment in the older age cohort that is recovered, compared to controls.
{"title":"Depression, Anxiety, and Stress with and without COVID-19 Infection","authors":"Snigdha Sinha, Alphonsa Jose K, S. Baboo","doi":"10.1055/s-0043-1768589","DOIUrl":"https://doi.org/10.1055/s-0043-1768589","url":null,"abstract":"Abstract Objectives Coronavirus disease 2019 (COVID-19) affects the respiratory system predominantly. However, post-COVID recovery, many manifested neurological and psychological symptoms, unrelated to the respiratory system. We aimed to estimate psychological impairment in individuals who were infected with COVID-19 in comparison with two uninfected control groups, and between different age cohorts. Materials and Methods We compared three groups with respect to COVID-19—those infected, those not infected but witness to someone infected, and those neither infected nor witness to anyone infected, along with age cohort comparison. The standard Depression, Anxiety and Stress Scale - 42 items (DASS 42) questionnaire, with additional questions were answered by 301 participants. Statistical Analysis SPSS was used for analyses, with Mann–Whitney U test, Kruskal–Wallis test, and Tukey's post hoc test. Results Significantly higher levels of depression, anxiety, and stress were found in the infected group than in the uninfected groups, and significant difference was found between the older age cohorts (50 and above) of each group. The percentages of the infected group with severe to very severe depression, anxiety, and stress were higher than the other groups. Conclusion There is greater psychological impairment in individuals post-COVID recovery, and there is higher impairment in the older age cohort that is recovered, compared to controls.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41513421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Introduction Palliative care of children (PCC) is a philosophical and a structured approach to providing tailored care to children with life-threatening diseases. Understanding the role of nurses and empowering them to take up the role of palliative care nurse are imperative to strengthen these services and make the palliative care services more accessible to the patients. Method The literature search was done in two database, PubMed and Scopus, using keyword and Medical Subject Headings (MeSH) terms such as children, palliative care, end of life, hospice, bereavement, and nursing. Records were screened by authors and relevant articles were included in the review. Discussion PCC should start with the diagnosis of the illness continue through all the phases of illness. Bereavement support to the family is also a part of palliative care. Nurses are in a key position to play important role in the PCC team. Nurses play various roles such as direct care provider, communicator, patient advocate, respite nurse, and counselor. Conclusion PCC is aimed to improve the quality of life of the child and family. It is crucial to achieving universal health coverage. Role of nurse is vital in providing PCC.
{"title":"Nursing Perspective of Providing Palliative Care to the Children—A Narrative Review","authors":"U. Agrawal, J. Sarin, R. Garg","doi":"10.1055/s-0043-1769081","DOIUrl":"https://doi.org/10.1055/s-0043-1769081","url":null,"abstract":"Abstract Introduction Palliative care of children (PCC) is a philosophical and a structured approach to providing tailored care to children with life-threatening diseases. Understanding the role of nurses and empowering them to take up the role of palliative care nurse are imperative to strengthen these services and make the palliative care services more accessible to the patients. Method The literature search was done in two database, PubMed and Scopus, using keyword and Medical Subject Headings (MeSH) terms such as children, palliative care, end of life, hospice, bereavement, and nursing. Records were screened by authors and relevant articles were included in the review. Discussion PCC should start with the diagnosis of the illness continue through all the phases of illness. Bereavement support to the family is also a part of palliative care. Nurses are in a key position to play important role in the PCC team. Nurses play various roles such as direct care provider, communicator, patient advocate, respite nurse, and counselor. Conclusion PCC is aimed to improve the quality of life of the child and family. It is crucial to achieving universal health coverage. Role of nurse is vital in providing PCC.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42280228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Chitosan is a versatile natural biomaterial that has been researched for a range of bio-dental applications. It possesses various desirable qualities such as biocompatibility, hydrophilicity, biodegradability, and a broad antibacterial range (covering Gram-negative and Gram-positive bacteria as well as fungi). Moreover, the molecular structure contains reactive functional groups, which provide numerous reaction sites and possibilities for the formation of electrochemical interactions at the cellular and molecular levels. Chitosan's unique features have attracted material scientists from all over the world to explore its applications in dentistry. The objective of this review is to highlight the creation of new chitosan biomaterials and as to how it is a vital component for the improvement and modification of existing dental materials being used.
{"title":"Application of Chitosan Biomaterials in Dentistry—A Narrative Review","authors":"N. Krishna, Nikita Lolayekar","doi":"10.1055/s-0043-1768591","DOIUrl":"https://doi.org/10.1055/s-0043-1768591","url":null,"abstract":"Abstract Chitosan is a versatile natural biomaterial that has been researched for a range of bio-dental applications. It possesses various desirable qualities such as biocompatibility, hydrophilicity, biodegradability, and a broad antibacterial range (covering Gram-negative and Gram-positive bacteria as well as fungi). Moreover, the molecular structure contains reactive functional groups, which provide numerous reaction sites and possibilities for the formation of electrochemical interactions at the cellular and molecular levels. Chitosan's unique features have attracted material scientists from all over the world to explore its applications in dentistry. The objective of this review is to highlight the creation of new chitosan biomaterials and as to how it is a vital component for the improvement and modification of existing dental materials being used.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48764562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anis Irmawati, Annisa Indah Pratiwi, Muh Rizki Aqsanu Azizi, Nur Apriliyanti, Ayu Annafi, Yassir Ahmad Azzaim, Ala'a Saif Alqhtani
Abstract Background Health problem that affects hard tissues of the teeth is dental caries, which is experienced by around 2.3 billion people in the world, with prevalence in Indonesia reaching 88.8. Direct pulp capping (DPC) is a vital pulp therapy used to maintain pulp vitality. Calcium hydroxide (Ca(OH) 2 ) is the gold standard pulp capping material, but has poor adhesion to dentin and mechanical properties, bacterial infiltration, formation of tunnel defects in the pulp resorption, and dentin bridge. Therefore, it is necessary to develop alternative therapy, namely, a combination of acemannan sponge and calcium phosphate cement (CPC)-calcium sulfate hemihydrate (CSH) for reparative dentin formation. Purpose This article describes the potential combination of acemannan sponge and CPC-CSH as DPC alternative materials for reparative dentin formation. Reviews Acemannan extracted from aloe vera exhibits anti-inflammatory, antimicrobial, and cytocompatibility properties. As DPC material, acemannan induces pulp proliferation and differentiation to osteoblast-like, growth factor synthesis, and promotes reparative dentin formation. However, acemannan sponge is radiolucent, allowing misinterpretation between pulp and acemannan sponge. CPC can be combined with CSH to shorten the setting time. CPC-CSH is radiopaque, has good compressive strength, and biocompatibility. CPC-CSH is a calcium-based material with neutral pH that can induce the dentin bridge formation. CPC-CSH showed good bioactivity because it induces the formation of apatite which plays a significant part in dentin and pulp regeneration. Conclusion The combination of acemannan sponge and CPC-CSH has the potential as DPC alternative materials for reparative dentin formation.
{"title":"Potential Combination of Acemannan Sponge and Calcium Phosphate Cement-Calcium Sulfate Hemihydrate (CPC-CSH) as Direct Pulp Capping Alternative Materials for Reparative Dentin Formation","authors":"Anis Irmawati, Annisa Indah Pratiwi, Muh Rizki Aqsanu Azizi, Nur Apriliyanti, Ayu Annafi, Yassir Ahmad Azzaim, Ala'a Saif Alqhtani","doi":"10.1055/s-0043-1768594","DOIUrl":"https://doi.org/10.1055/s-0043-1768594","url":null,"abstract":"Abstract Background Health problem that affects hard tissues of the teeth is dental caries, which is experienced by around 2.3 billion people in the world, with prevalence in Indonesia reaching 88.8. Direct pulp capping (DPC) is a vital pulp therapy used to maintain pulp vitality. Calcium hydroxide (Ca(OH) 2 ) is the gold standard pulp capping material, but has poor adhesion to dentin and mechanical properties, bacterial infiltration, formation of tunnel defects in the pulp resorption, and dentin bridge. Therefore, it is necessary to develop alternative therapy, namely, a combination of acemannan sponge and calcium phosphate cement (CPC)-calcium sulfate hemihydrate (CSH) for reparative dentin formation. Purpose This article describes the potential combination of acemannan sponge and CPC-CSH as DPC alternative materials for reparative dentin formation. Reviews Acemannan extracted from aloe vera exhibits anti-inflammatory, antimicrobial, and cytocompatibility properties. As DPC material, acemannan induces pulp proliferation and differentiation to osteoblast-like, growth factor synthesis, and promotes reparative dentin formation. However, acemannan sponge is radiolucent, allowing misinterpretation between pulp and acemannan sponge. CPC can be combined with CSH to shorten the setting time. CPC-CSH is radiopaque, has good compressive strength, and biocompatibility. CPC-CSH is a calcium-based material with neutral pH that can induce the dentin bridge formation. CPC-CSH showed good bioactivity because it induces the formation of apatite which plays a significant part in dentin and pulp regeneration. Conclusion The combination of acemannan sponge and CPC-CSH has the potential as DPC alternative materials for reparative dentin formation.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42506284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Shaji, Hima Jacob, Chandana Shivaiah, Abhishek B. P.
Abstract Objectives This article determines the number of correct responses under confrontation naming, producing category coordinates, superordinates, and features associated with the target. Materials and Methods Thirty participants in the age range of 18 to 30 years served as participants. The study was carried out in Malayalam, the native language of the participants. A conditioned naming task was administered to the participants. Statistical Analysis Within-group analysis was carried out using Friedman's test. Results It was found that the participants erred more in naming category coordinates, derivatives, and superordinates. Conclusion The amount of cognitive control varied for each of these conditional naming tasks, and with increasing complexity in cognitive control, scores on conditional naming tasks also differed, showing the relationship between these two aspects.
{"title":"Role of Executive Functions in Lexical Selection","authors":"S. Shaji, Hima Jacob, Chandana Shivaiah, Abhishek B. P.","doi":"10.1055/s-0043-1768596","DOIUrl":"https://doi.org/10.1055/s-0043-1768596","url":null,"abstract":"Abstract Objectives This article determines the number of correct responses under confrontation naming, producing category coordinates, superordinates, and features associated with the target. Materials and Methods Thirty participants in the age range of 18 to 30 years served as participants. The study was carried out in Malayalam, the native language of the participants. A conditioned naming task was administered to the participants. Statistical Analysis Within-group analysis was carried out using Friedman's test. Results It was found that the participants erred more in naming category coordinates, derivatives, and superordinates. Conclusion The amount of cognitive control varied for each of these conditional naming tasks, and with increasing complexity in cognitive control, scores on conditional naming tasks also differed, showing the relationship between these two aspects.","PeriodicalId":40092,"journal":{"name":"Journal of Health and Allied Sciences NU","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47981450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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