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Influence of Hip Mobility and Strength on Gait Parameters among Young Females—A Cross-Sectional Study 髋部活动和力量对年轻女性步态参数影响的横断面研究
Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-09-29 DOI: 10.1055/s-0043-1775716
Nityal Kumar Alagingi, Deekshitha Salin
Abstract Background The hip's primary function is to dynamically support the weight of the trunk while allowing the force and load transmission axial skeleton to the lower extremity and henceforth allowing mobility. The function of the hip is not only to take the load of the trunk to the lower extremity but also to perform daily activities which include walking, running, jumping, sitting, etc. Hip muscle strength is required to stabilize the pelvic and trunk during squatting and walking (single stance) and to perform other daily living activities. The prevalence rate reports that males are more physically active than females. The number of physical activities has shown to be decreased in teens and young adults between the ages of 14 and 22 years due to transitions in their lifestyle. These changes can be behavioral and due to body composition. The objectives of the study are to determine the influence of hip mobility and strength on the spatial and temporal parameters of gait. Methodology This is a cross-sectional study involving a total of 50 young female populations that have been selected based on the inclusion criteria. Hip range of motion using a universal goniometer was measured in three trials with 30 seconds of rest between each measurement. The hip muscle strength was measured using a handheld dynamometer with 5 seconds hold and three trials taking 30 seconds of rest between each measurement. Spatial parameters of gait were measured by using Kinovea software V.0.8.15, and temporal parameters of gait were measured by asking the subject to walk comfortably in their own speed for 1 minute and the video was taken and measured. Result The hip internal rotation and external rotation has shown to have a statistical significance with spatial and temporal parameters of gait. The hip abductors, adductors, internal rotators, and external rotator muscle strength have shown to have statistical significance with spatial and temporal parameters of gait. Descriptive statistics were used for demographic characteristics, and Pearson's correlation coefficient is used for determining association between outcome variables. Conclusion The hip abductors, adductors, internal rotators, and external rotators have shown to have influence on gait parameters specially with walking speed. The hip internal and external rotation has shown to have influence on gait parameters.
髋关节的主要功能是动态支撑躯干的重量,同时使力和载荷向轴向骨架传递到下肢,从而实现活动。髋关节的功能不仅是将躯干的负荷转移到下肢,而且还能进行日常活动,包括走路、跑步、跳跃、坐着等。在下蹲和行走(单站)以及进行其他日常生活活动时,需要臀部肌肉力量来稳定骨盆和躯干。流行率报告显示,男性比女性更活跃。在14至22岁的青少年和年轻人中,由于生活方式的转变,体育活动的数量有所减少。这些变化可能是行为上的,也可能是身体成分造成的。该研究的目的是确定髋关节活动度和力量对步态空间和时间参数的影响。这是一项横断面研究,涉及根据纳入标准选择的50名年轻女性人群。在三次试验中使用通用角计测量髋关节活动范围,每次测量之间休息30秒。使用手持式测力仪测量臀部肌肉力量,保持5秒,每次测量之间休息30秒,进行三次试验。步态空间参数测量采用Kinovea软件V.0.8.15,步态时间参数测量采用要求被试以自己的速度舒适行走1分钟,并拍摄视频测量。结果髋内旋和髋外旋与步态时空参数均有统计学意义。髋关节外展肌、内收肌、内旋肌和外旋肌力量与步态的时空参数有统计学意义。人口统计学特征采用描述性统计,Pearson相关系数用于确定结果变量之间的相关性。结论髋关节外展肌、内收肌、内旋肌和外旋肌对步态参数有影响,尤其是对步行速度有影响。髋关节内外旋转已被证明对步态参数有影响。
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引用次数: 0
New Research Areas in Clinical Microbiology 临床微生物学新研究领域
Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-09-22 DOI: 10.1055/s-0043-1772845
Volker Gurtler
I would like to outline a few areas in Clinical Microbiology that have become major research disciplines over the last 10 years that may now impact Health and Allied Sciences. They encompass (1) COVID-19, (2) biofilms, (3) microbiomes, (4) nanotechnology, and (5) probiotics. As well as being direct research areas, they overlap with each other, and they are beginning to overlap in important ways with Health and Allied Sciences—hence the importance of contributing papers on these subjects to the Journal of Health and Allied Sciences NU (JHAS-NU).
我想概述临床微生物学的几个领域,这些领域在过去十年中已经成为主要的研究学科,现在可能会影响健康和相关科学。它们包括(1)COVID-19,(2)生物膜,(3)微生物组,(4)纳米技术和(5)益生菌。作为直接的研究领域,它们彼此重叠,并且它们开始在重要的方面与健康和相关科学重叠——因此,在《健康和相关科学杂志》(JHAS-NU)上发表这些主题的论文非常重要。
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引用次数: 0
Knowledge of Dental Students about Erythroplakia as an Oral Potentially Malignant Disorder 口腔科学生对红斑作为口腔潜在恶性疾病的认识
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-09-05 DOI: 10.1055/s-0043-1774299
Kelvin Alfan Nola Anggarista, Meysinta A. Datau, F. Mahdani, D. Radithia, D. Ernawati, M. Surboyo
Abstract Background  Erythroplakia is a rare oral potentially malignant disease (OPMD) lesion with prevalence ranging from 0.02 to 0.83%, but it has a higher possibility of malignant transformation, ranging from 14 to 50%. Early detection is crucial for better patient prognosis, but it is challenging for preclinical and clinical dental students to recognize erythroplakia. Objective  The aim of this study was to identify the level of knowledge of dental students about erythroplakia as an OPMD lesion based on their academic level. Methods  This analytical cross-sectional study used a simple randomized sampling design. Data were cross-tabulated to describe the knowledge of erythroplakia. Results  In total, 167 respondents completed the questionnaire, with the majority of 130 (77.84%) being females and 65 (38.92%) were older than 21 years. The majority of respondents, 122 (73.05%), had moderate knowledge, while 31 (18.57%) had poor knowledge and 14 (8.38%) had good knowledge of erythroplakia in terms of etiology, predisposition factors, clinical presentation, diagnosis, treatment, and prognosis. Conclusion  Most of the dental students included in the study had intermediate level of knowledge of erythroplakia as an OPMD lesion.
摘要背景红斑病是一种罕见的口腔潜在恶性疾病(OPMD)病变,患病率为0.02 ~ 0.83%,但其恶性转化的可能性较高,为14% ~ 50%。早期发现对更好的患者预后至关重要,但临床前和临床牙科学生识别红斑病是具有挑战性的。目的了解牙科专业学生对红斑病作为OPMD病变的认知水平。方法本研究采用简单随机抽样设计。数据交叉表,以描述对红细胞增多症的认识。结果共167人完成问卷调查,其中女性130人(77.84%),年龄在21岁以上的65人(38.92%)。调查对象中,对红斑病的病因、易感因素、临床表现、诊断、治疗、预后的了解程度一般的有122人(73.05%),较差的有31人(18.57%),较好的有14人(8.38%)。结论本研究中大多数牙科学生对红斑病作为OPMD病变有中等水平的认识。
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引用次数: 0
Association of Risk Factors with At-Risk Cases of Autism 危险因素与自闭症高危病例的关系
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-09-05 DOI: 10.1055/s-0043-1774287
Reena Ravi, T. Mendonca
Abstract A neurological condition known as autism spectrum disorder (ASD) first manifests before the age of 3. Numerous factors may have an impact on the development of autism; however, its precise causes are yet unknown. The research aims to identify certain risk factors that associate with children at a higher risk of developing autism. This study is a descriptive analysis of 80 children who were identified as being at risk for autism and meeting the requirements of the Modified Checklist for Autism in Toddlers at the community health center. A semistructured proforma was used to collect the baseline data from the mother and the child. Through the use of a thoughtfully created checklist, each child enrolled in the study had a thorough history completed, including the suspected prenatal, intranatal, neonatal, and infant risk factors with the help of their mothers. Descriptive statistics with frequency percentages were adopted for the demographic data of the participants. To find the association between possible risk factors and at-risk cases of ASD, an independent t -test was used. Fisher's exact test and Pearson's chi-squared test ( p  = 0.05, confidence interval = 95%) were used to find how the risks (odds ratios) of the factors studied affect the incidence of ASD. It was discovered that prenatal risk factors, such as pregnancy-related infections and medication use, were statistically significantly linked to an increased risk for autism. Significant intranatal risk factors for autism risk included a breech presentation, cesarean section, forced labor, and resuscitation at birth. Similar to this, the neonatal risk factors included maternal hemorrhage, Rh or ABO incompatibility, birth injuries, and feeding problems. Poor socioeconomic status and seizures were the baby risk variables, both of which were statistically significant and linked to an increased chance of autism. The results of the study support an array of perinatal, intranatal, neonatal, and infant risk factors linked to the likelihood of developing autism.
摘要一种被称为自闭症谱系障碍(ASD)的神经系统疾病在3岁前首次出现。许多因素可能对自闭症的发展产生影响;然而,其确切原因尚不清楚。这项研究旨在确定与自闭症风险较高的儿童相关的某些风险因素。这项研究是对80名儿童的描述性分析,这些儿童被确定为有患自闭症的风险,并符合社区卫生中心幼儿自闭症改良检查表的要求。使用半结构形式表来收集母亲和孩子的基线数据。通过使用精心编制的检查表,参与研究的每个孩子都完成了一份完整的病史,包括在母亲的帮助下疑似产前、产前、新生儿和婴儿的风险因素。参与者的人口统计数据采用了频率百分比的描述性统计。为了找出可能的危险因素与ASD高危病例之间的相关性,使用了独立的t检验。Fisher精确检验和Pearson卡方检验(p = 0.05,置信区间 = 95%)用于了解所研究因素的风险(比值比)如何影响ASD的发生率。研究发现,产前风险因素,如妊娠相关感染和药物使用,在统计学上与自闭症风险增加显著相关。自闭症风险的重要产前风险因素包括臀位、剖宫产、强迫分娩和出生时复苏。与此类似,新生儿的危险因素包括母亲出血、Rh或ABO血型不合、出生伤害和喂养问题。不良的社会经济地位和癫痫发作是婴儿的风险变量,这两个变量都具有统计学意义,并与患自闭症的几率增加有关。这项研究的结果支持了一系列与患自闭症的可能性相关的围产期、产前、新生儿和婴儿风险因素。
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引用次数: 0
Modulation of Small-Intestine Morphology in Mice by a Novel Supplement Containing Silybum marianum, Yeast β-Glucan, Prebiotics, and Minerals 含有水飞蓟、酵母β-葡聚糖、益生元和矿物质的新型补充剂对小鼠小肠形态的调节
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-08-31 DOI: 10.1055/s-0043-1773807
R. Nucci, Victor Nehmi-Filho, M. Bastos, J. A. de Freitas, J. Otoch, A. Pessoa, W. Jacob-Filho
Abstract Silymarin, derived from Silybum marianum , has recently demonstrated its potential to improve health in conditions such as obesity and metabolic disturbances. Understanding the impact of nutraceuticals on intestinal morphology is crucial for developing supplements that promote a higher quality of life. Therefore, this study aimed to investigate the effects of nutraceutical supplementation with silymarin on the morphology of the small intestine. Sixty-day-old adult male C57BL/6 mice were divided into two groups: one receiving a standard chow (control) and the other receiving a novel silymarin supplement (experimental). Following the experimental period, the animals were euthanized, and fragments of the small intestine were collected for histochemical analysis using Masson's trichrome and periodic acid-Schiff with Alcian blue staining techniques. Our results revealed an increase in the number of villi per analyzed field in the experimental group, accompanied by a decrease in basic mucin, crypt depth, mucosal thickness, and villus spacing. In conclusion, this novel nutraceutical supplementation may play a crucial role in modulating small intestine morphology and enhancing absorption capacity.
摘要水飞蓟素,从水飞蓟中提取,最近被证明具有改善肥胖和代谢紊乱等健康状况的潜力。了解营养保健品对肠道形态的影响对于开发提高生活质量的补充剂至关重要。因此,本研究旨在探讨添加水飞蓟素的营养保健品对小肠形态的影响。将60日龄成年雄性C57BL/6小鼠分为两组,一组喂食标准饲料(对照组),另一组喂食新型水飞蓟素补充剂(实验组)。实验结束后,对动物实施安乐死,并收集小肠碎片进行组织化学分析,使用马松三色和周期性酸希夫与阿利新蓝染色技术。我们的结果显示,实验组每分析场的绒毛数量增加,同时伴有碱性黏液蛋白、隐窝深度、粘膜厚度和绒毛间距的减少。综上所述,这种新型营养补充剂可能在调节小肠形态和增强吸收能力方面发挥重要作用。
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引用次数: 0
ADC Mapping and T2 Mapping of the Lumbar Spine to Assess Disc Degeneration: A Review 腰椎的ADC和T2成像评估椎间盘退变:综述
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-08-29 DOI: 10.1055/s-0043-1772823
S. Abhijith, Kayalvizhi Ravichandran
Abstract Early detection of disc degeneration and categorizing them is very important for the treatment plan and better prognosis. We aimed to assess the efficacy of apparent diffusion coefficient (ADC) mapping and T2 mapping in the early detection and grading of the severity of degenerative disc disease. In this review, the articles published until July 2022, from the PubMed database were used. All articles contained information about the application of ADC and T2 mapping in the detection of disc degeneration. A total of 40 articles were included in this review. We assessed each article for the feasibility of both techniques to categorize the degeneration. ADC values of nucleus pulposus (NP) showed a negative correlation with Pfirrmann grades and age. T2 values of NP and annulus fibrosus (AF) are significantly decreased with an increase in Pfirrmann grades. And also, as age increases, T2 values of NP and posterior AF decreased significantly. ADC and T2 mapping techniques are sensitive in the detection and categorization of disc degeneration. It is highly recommended to include quantitative magnetic resonance imaging techniques in routine spine imaging protocol in a patient with complaints of back pain.
椎间盘退变的早期发现和分类对于制定治疗计划和改善预后非常重要。我们旨在评估表观扩散系数(ADC)标测和T2标测在退行性椎间盘疾病严重程度的早期检测和分级中的有效性。在这篇综述中,使用了PubMed数据库中截至2022年7月发表的文章。所有文章都包含了ADC和T2标测在椎间盘退变检测中的应用信息。本综述共收录了40篇文章。我们评估了每一篇文章的可行性,这两种技术来分类退化。髓核ADC值与Pfirrmann分级和年龄呈负相关。NP和纤维环(AF)的T2值随着Pfirrmann分级的增加而显著降低。而且,随着年龄的增长,NP和后房颤的T2值显著降低。ADC和T2标测技术在椎间盘退变的检测和分类中是敏感的。强烈建议将定量磁共振成像技术纳入背痛患者的常规脊柱成像方案中。
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引用次数: 0
An Account of a Giant Adolescent Vulvar Lipoma 青少年巨大外阴脂肪瘤一例报告
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-08-28 DOI: 10.1055/s-0043-1772822
Garima Vats, A. DCunha, Sandeep B. Rai, U. Raghuraj
Abstract Though they are commonly known as “universal tumors,” lipomas are rarely found in the vulva. In this report, we discuss the case of a 15-year-old girl who presented with an enormous (26.5 × 21.5 × 6.5 cm) left labial swelling that had been progressively enlarging for a year and had led to extensive distortion of the vulvar anatomy. Following imaging, surgical excision with vulvar reconstruction was performed focusing on esthesis and function. Pathological examination confirmed the clinical and radiological diagnosis of a lipoma. The patient is doing clinically well at 1 year of follow-up with significant improvement in her academic performance and self-esteem.
摘要尽管脂肪瘤通常被称为“普遍性肿瘤”,但在外阴很少发现。在本报告中,我们讨论了一名15岁女孩的案例,她患有巨大的(26.5 × 21.5 × 6.5 cm)左唇肿胀,该肿胀已经持续了一年并导致外阴解剖结构的广泛扭曲。影像学检查后,进行外阴重建手术切除,重点关注感觉和功能。病理检查证实了脂肪瘤的临床和放射学诊断。患者在1年的随访中临床表现良好,学习成绩和自尊显著改善。
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引用次数: 0
Prophage and Plasmid-Mediated Beta-Lactamases in Multidrug-Resistant Extraintestinal Escherichia coli 多重耐药肠外大肠杆菌中β-内酰胺酶的预防和质粒介导
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-08-24 DOI: 10.1055/s-0043-1772707
J. Raj, Akshatha Dinesh, R. Vittal, A. Rohit
Abstract Objectives  Antibiotic resistance can arise as a mutation to adapt to stress or be mediated by horizontal gene transfer. This study aimed at identifying the resistance determinants present in the mobile genetic elements of prophages and plasmids within multidrug-resistant (MDR) extraintestinal Escherichia coli . Materials and Methods  Thirty-five anonymized MDR E. coli isolates of nonintestinal infections were confirmed for their antimicrobial resistance to six categories of antimicrobials by the disk diffusion test. Genes coding for beta-lactamases and carbapenemases in bacterial genome, plasmid, and prophage fractions were separately determined by polymerase chain reaction. Transducing ability of prophages carrying resistance genes was determined. Results  Twenty-six isolates were positive for the gene bla CTX-M , nine for bla TEM , one each for bla KPC and bla VIM , thirteen for bla NDM, and seven for bla OXA . A majority of these isolates carried these determinants in plasmids and prophage fractions. Twenty-one percent of the prophage fractions (4 of 19) were able to successfully transfer resistance to sensitive isolates. Conclusions  This study indicates bla CTX-M , bla TEM, and bla NDM genes that are reported most frequently in MDR isolates are more frequent in the plasmid and prophage fractions thus supporting for increased mobility.
抽象目标 抗生素耐药性可以作为适应压力的突变产生,也可以通过水平基因转移介导。本研究旨在鉴定多药耐药(MDR)肠外大肠杆菌中原噬菌体和质粒的可移动遗传元件中存在的耐药性决定因素。材料和方法 通过纸片扩散试验证实了35株非肠道感染的匿名耐多药大肠杆菌分离株对六类抗菌药物的耐药性。通过聚合酶链式反应分别测定细菌基因组、质粒和原噬菌体组分中编码β-内酰胺酶和碳青霉烯酶的基因。测定了携带抗性基因的原噬菌体的转导能力。后果 26个分离株对bla-CTX-M基因呈阳性,9个对bla-TEM呈阳性,bla-KPC和bla-VIM各1个,13个对bla-NDM呈阳性,7个对bla-OXA呈阳性。这些分离物中的大多数在质粒和原噬菌体部分中携带这些决定簇。21%的原噬菌体组分(19个中的4个)能够成功地将抗性转移到敏感分离株。结论 这项研究表明,在MDR分离株中报道最频繁的bla-CTX-M、bla-TEM和bla-NDM基因在质粒和原噬菌体组分中更频繁,从而支持增加的迁移率。
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引用次数: 0
Hypereosinophilia Syndrome: Myriad Presentation—A Case Report 嗜酸性粒细胞增多综合征:一例报告
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-08-24 DOI: 10.1055/s-0043-1772743
Mansi Patel, Divit Shah, Sujal G Patel, S. Acharya, S. Sushanth Kumar, S. Shukla
Abstract Hypereosinophilic syndrome is a myeloproliferative disorder that is distinguished with the presence of eosinophilia, which is an absolute eosinophil level of more than 1500/µL for no less than 6 months, no recognized cause for eosinophilia, and clear organ involvement characteristics. But, in some cases where patients require therapy to decrease eosinophil counts due to severe symptoms, a lower time period of hypereosinophilic is also admissible. In this case series, we have included three cases in which first case presented with the features of diarrhea, nausea, and decreased appetite who underwent colonoscopy and was diagnosed as a case of eosinophilic colitis. The second patient was a female came with abdominal pain and burning micturition, who was having eosinophilia on blood count examination and was diagnosed as a case of eosinophilic cystitis. Third case was young female who was diagnosed as eosinophilic endocarditis on two-dimensional echocardiography having dyspnea and rash and high eosinophil count on blood smear. All the three patients were started on steroids, who recovered well with medication and were discharged for follow-up after 7 days with complete blood count.
摘要:高嗜酸性粒细胞综合征是一种骨髓增生性疾病,其特征是存在嗜酸性细胞增多症,即嗜酸性细胞绝对水平超过1500/µL,持续时间不少于6个月,没有公认的嗜酸性细胞增生原因,且有明确的器官受累特征。但是,在某些情况下,患者因严重症状需要治疗以减少嗜酸性粒细胞计数,较短的嗜酸性粒增多期也是可以接受的。在这个病例系列中,我们纳入了三个病例,其中第一个病例表现为腹泻、恶心和食欲下降,接受了结肠镜检查,并被诊断为嗜酸性结肠炎。第二名患者是一名女性,患有腹痛和灼热性排尿,在血液计数检查中出现嗜酸性粒细胞增多症,被诊断为嗜酸性膀胱炎。第三例为年轻女性,经二维超声心动图诊断为嗜酸性心内膜炎,伴有呼吸困难和皮疹,血涂片嗜酸性粒细胞计数高。所有三名患者都开始服用类固醇,药物治疗后恢复良好,7天后出院随访,血细胞计数完全。
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引用次数: 0
Analysis on the Knowledge about Oral Potentially Malignant Disorders of a Male Motorcycle Community in Indonesia 印尼一男性摩托车社区口腔潜在恶性疾病知识分析
IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-08-21 DOI: 10.1055/s-0043-1772681
Rafdan Affan Ahmada, Deananda Setio Ramadhanti, M. Surboyo, A. Parmadiati, D. Ernawati, F. Mahdani, N. Ayuningtyas
Abstract Background  Oral potentially malignant disorders (OPMDs) are a group of oral lesions or conditions with a higher risk of malignant transformation. OPMD affects 4.47% of people worldwide, with predilection in males. The high tendency of frequent tobacco smoking and alcohol consumption may lead the male motorcycle community to have a higher risk for developing OPMD and malignant transformation. Objectives  This article determines the level of knowledge about OPMD within a male motorcycle community. Methods  This study uses a survey research design that is a questionnaire-based and descriptive study. Data were obtained using a Google Form, and IBM SPSS was used for analysis. Simple random sampling is the sampling method applied. The total knowledge score is divided into three levels, low (0–4), moderate (5–9), and high (10–15). Results  The questionnaire was finished by 60 people entirely. All respondents (100%) were men, and the majority (83.00%) was aged between 20 and 21. A total of 26 respondents (43.30%) had moderate knowledge levels, followed by 21 with high knowledge levels (35.0%), and 13 with low knowledge levels (21.70%). Conclusion  The majority of the male motorcycle community (43.30%) has a moderate knowledge level regarding OPMD. This study indicates the need for educational measures to improve awareness regarding OPMD in a high-risk community.
摘要背景 口腔潜在恶性疾病(OPMD)是一组恶性转化风险较高的口腔病变或病症。全世界4.47%的人患有OPMD,其中男性更为常见。频繁吸烟和饮酒的高趋势可能导致男性摩托车社区患OPMD和恶性转化的风险更高。目标 本文确定了男性摩托车社区中有关OPMD的知识水平。方法 本研究采用问卷调查和描述性研究相结合的调查研究设计。使用谷歌表格获取数据,并使用IBM SPSS进行分析。简单随机抽样是所采用的抽样方法。知识总分分为三个等级,低(0-4)、中等(5-9)和高(10-15)。后果 调查问卷共有60人完成。所有受访者(100%)为男性,大多数(83.00%)年龄在20至21岁之间。共有26名受访者(43.30%)具有中等知识水平,其次是21名知识水平高的受访者(35.0%)和13名知识水平低的受访者(21.70%) 大多数男性摩托车社区(43.30%)对OPMD具有中等的知识水平。这项研究表明,需要采取教育措施来提高高危社区对OPMD的认识。
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引用次数: 0
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