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The Molecular Spectrum of Beta-Thalassemia Mutations in Southeastern, Turkey 土耳其东南部β地中海贫血突变体的分子光谱
IF 0.1 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.12
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引用次数: 0
Multivariate Analysis of the Factors Affecting Tinnitus Severity in Old Age: A Multi-Center Cross-Sectional Study 影响老年人耳鸣严重程度因素的多因素分析:一项多中心横断面研究
IF 0.1 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.5
F. Ozer, Gözde Bayramoglu Cabuk, M. Mutlu, Serap Er, Agit Simsek, S. Erbek
Aim: The purpose of this study was to analyze the factors affecting tinnitus severity in the population aged 60 and over with a multi-central data and with multivariate analysis. Materials: This prospective study was composed of 130 subjects aged 60 years or older with clinical complaint of tinnitus and administered to five different otorhinolaryngology clinics in four different cities in our country. All participants have been tested with pure tone audiometry. Tinnitus loudness and pitch mapping were determined for all participants. All participants also interviewed individually to complete Tinnitus Handicap Inventory (THI) and asked to characterize their tinnitus symptoms using a visual analog scale (VAS) measuring severity, annoyance of tinnitus. Results: Tinnitus loudness increases significantly in the group over the age of 79, but there is no significant difference between the groups formed according to age in terms of VAS or THI values. Systemic disease does not make a significant difference that increases the severity of tinnitus. risk factors that increase tinnitus severity are included in the logistic regression analysis;High level of education and advanced age over 79 years were determined as independent risk factors. Increasing education level is an independent risk factor for increasing tinnitus severity with an odds ratio of 2.46 (95% CI, 1.080-5.624). At the same time, advanced age over 79 years is an independent risk factor with an odds ratio of 5.4 (95% CI, 1,385-21.197), which causes tinnitus severity to be felt more. Conclusion: In old age population, the incidence of tinnitus does not increase with increasing age, but tinnitus severity increases. As hearing loss increases, tinnitus severity and VAS score increase. According to the results of this study, the most important risk factors that increase the perception of tinnitus in the elderly population were determined as very advanced age and high education level. It is reasonable to think that one of the reasons for this is that the elderly in the vulnerable group for the Covid 19 pandemic should stay away from hospitals unless their tinnitus complaints are very serious. Re-performing our study in elderly individuals after the pandemic is important to see the effect of the pandemic period more clearly in these individuals.
目的:本研究的目的是用多中心数据和多变量分析来分析影响60岁及以上人群耳鸣严重程度的因素。材料:这项前瞻性研究由130名60岁或以上有耳鸣临床症状的受试者组成,他们在我国四个不同城市的五家不同的耳鼻喉科诊所接受了治疗。所有参与者都接受了纯音听力测试。确定所有参与者的耳鸣响度和音高映射。所有参与者还进行了单独访谈,以完成耳鸣障碍量表(THI),并被要求使用视觉模拟量表(VAS)来表征他们的耳鸣症状,该量表测量耳鸣的严重程度和烦恼程度。结果:79岁以上的组耳鸣响度显著增加,但根据年龄形成的组之间的VAS或THI值没有显著差异。系统性疾病不会对耳鸣的严重程度产生显著影响。增加耳鸣严重程度的风险因素包括在逻辑回归分析中;高教育水平和79岁以上的高龄被确定为独立的危险因素。教育水平的提高是耳鸣严重程度增加的一个独立风险因素,比值比为2.46(95%CI,1.080-5.624)。同时,79岁以上的高龄是一个独立的风险因素,其比值比为5.4(95%CI,1385-21.197),这会使耳鸣的严重程度更加明显。结论:在老年人群中,耳鸣的发生率不会随着年龄的增长而增加,但耳鸣的严重程度会增加。随着听力损失的增加,耳鸣的严重程度和VAS评分也会增加。根据这项研究的结果,增加老年人耳鸣感知的最重要风险因素被确定为高龄和高教育水平。有理由认为,造成这种情况的原因之一是,新冠肺炎19大流行的弱势群体中的老年人应该远离医院,除非他们的耳鸣症状非常严重。在大流行后重新对老年人进行研究,对于更清楚地了解大流行期对这些人的影响很重要。
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引用次数: 0
Metabolic Syndrome and Cardiovascular Problems Associated with Different Types of Diet 与不同饮食类型相关的代谢综合征和心血管问题
IF 0.1 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.22
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引用次数: 0
Breast Cancer, Thyroid Cancer and Bladder Cancer in a Family with a Novel Germline Frameshift Variant SDHB c.676_677del: A Case Report 一个具有新种系移架变异株SDHB c.676_677del的家族中的癌症、癌症和癌症:病例报告
IF 0.1 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.18
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引用次数: 0
Depression at Health Schools 健康学校的抑郁症
IF 0.1 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.7
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引用次数: 0
A Detailed Topographic Neurovascular Anatomy for Vestibular Neurosurgery 前庭神经外科的详细神经血管解剖
IF 0.1 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.10
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引用次数: 0
Curriculum Development for Upper Endoscopy Training in Surgical Education 外科教育中上内镜培训课程的开发
IF 0.1 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.25
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引用次数: 0
Inadequate Amyloid Clearance in Alzheimer's Disease: The Possible Role of TTR Transporter Protein and LRP-1 Receptor 阿尔茨海默病中淀粉样蛋白清除不足:TTR转运蛋白和LRP-1受体的可能作用
IF 0.1 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.23
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引用次数: 0
“Universal Tumor” for a Reason, Uncommon Lipoma over Thumb 拇指上罕见脂肪瘤是“万能瘤”的原因
IF 0.1 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.19
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引用次数: 0
Endoplasmic Reticulum Stress Response in Non-Alcholic Fatty Liver Disease: Sophisticated Pathways 非酒精性脂肪肝的内质网应激反应:复杂的途径
IF 0.1 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.20
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引用次数: 0
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Gazi Medical Journal
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