M. Sultan, N. Kosai, R. Rajan, M. Taher, Aznan Shuhaili, D. C. Febriany, Nadir Bir Hastalık
We are discussing a case of malignant melanoma of esophagus, initially presented to us with very atypical presentation. On further history, patient claim having dysphagia for few months, initially to solid then followed by liquid, progressively worsening over few months. On further examination, OGDS reveal pedunculated growth at 30cm and 32 cm with skip free intact mucosa in between. Subsequently, we optimize his nutritional status and performed open tranhiatal total esophagectomy with cervical anastomosis and feeding jejunostomy. Post-operative recovery was uneventful, and patient was well upon discharge. Histopathology of the specimen revealed malignant melanoma of the esophagus. On subsequent follow up. PET scan was also done and shows stable disease with no evidence of tumor recurrence.
{"title":"Malignant Melanoma of Oesophagus: A Rare Entity","authors":"M. Sultan, N. Kosai, R. Rajan, M. Taher, Aznan Shuhaili, D. C. Febriany, Nadir Bir Hastalık","doi":"10.12996/gmj.2023.17","DOIUrl":"https://doi.org/10.12996/gmj.2023.17","url":null,"abstract":"We are discussing a case of malignant melanoma of esophagus, initially presented to us with very atypical presentation. On further history, patient claim having dysphagia for few months, initially to solid then followed by liquid, progressively worsening over few months. On further examination, OGDS reveal pedunculated growth at 30cm and 32 cm with skip free intact mucosa in between. Subsequently, we optimize his nutritional status and performed open tranhiatal total esophagectomy with cervical anastomosis and feeding jejunostomy. Post-operative recovery was uneventful, and patient was well upon discharge. Histopathology of the specimen revealed malignant melanoma of the esophagus. On subsequent follow up. PET scan was also done and shows stable disease with no evidence of tumor recurrence.","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41743714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Contribution to the History of Hearing Screening Programs: Dr. Muhiddin Hekimbaşızâde’s Recommendations for Hearing Screening at School Entry a Century Ago","authors":"","doi":"10.12996/gmj.2023.26","DOIUrl":"https://doi.org/10.12996/gmj.2023.26","url":null,"abstract":"","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49234084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tuberculosis is one of the main causes of death due to infections in the world. Extrapulmonary infection accounts for one third of the cases, of which abdominal tuberculosis may present with mesenteric lymphadenitis, peritonitis, gastrointestinal system involvement or solid organ involvement. Among them, isolated mesenteric tuberculous lymphadenitis (IMTL) is a type of extrapulmonary disease characterized by the involvement of intraabdominal lymph nodes mostly due to lymphohematogenous spread of primary mycobacterium tuberculosis. IMTL is a rare clinical entity in children and is often associated with underlying immunosuppressive disorders. Chronic abdominal pain, intermittent fever, and weight loss are the classic clinical presentations of this disease. In this paper, a rare case of IMTL in a healthy fifteen-year-old girl is reported.
{"title":"A Rare Cause of Chronic Abdominal Pain in Children: Isolated Mesenteric Tuberculous Lymphadenitis","authors":"Aziz Serhat Baykara, A. Yilmaz, K. Cetin","doi":"10.12996/gmj.2023.15","DOIUrl":"https://doi.org/10.12996/gmj.2023.15","url":null,"abstract":"Tuberculosis is one of the main causes of death due to infections in the world. Extrapulmonary infection accounts for one third of the cases, of which abdominal tuberculosis may present with mesenteric lymphadenitis, peritonitis, gastrointestinal system involvement or solid organ involvement. Among them, isolated mesenteric tuberculous lymphadenitis (IMTL) is a type of extrapulmonary disease characterized by the involvement of intraabdominal lymph nodes mostly due to lymphohematogenous spread of primary mycobacterium tuberculosis. IMTL is a rare clinical entity in children and is often associated with underlying immunosuppressive disorders. Chronic abdominal pain, intermittent fever, and weight loss are the classic clinical presentations of this disease. In this paper, a rare case of IMTL in a healthy fifteen-year-old girl is reported.","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46440029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bir Tip Fakultesi Son Sinif Ogrencilerinde Anksiyete ve Depresyon Duzeyi ve Iliskili Faktorler","authors":"","doi":"10.12996/gmj.2023.1","DOIUrl":"https://doi.org/10.12996/gmj.2023.1","url":null,"abstract":"","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44994089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cytogenetic Profile and Phenotypical and Reproductive Complaints in 39 Patients with Turner Syndrome: A Single Center Experience ASA ve ARISCAT Risk Indeksinin Degerlendirilmesi","authors":"","doi":"10.12996/gmj.2023.6","DOIUrl":"https://doi.org/10.12996/gmj.2023.6","url":null,"abstract":"","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44588501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Molecular Spectrum of Beta-Thalassemia Mutations in Southeastern, Turkey","authors":"","doi":"10.12996/gmj.2023.12","DOIUrl":"https://doi.org/10.12996/gmj.2023.12","url":null,"abstract":"","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44383591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Ozer, Gözde Bayramoglu Cabuk, M. Mutlu, Serap Er, Agit Simsek, S. Erbek
Aim: The purpose of this study was to analyze the factors affecting tinnitus severity in the population aged 60 and over with a multi-central data and with multivariate analysis. Materials: This prospective study was composed of 130 subjects aged 60 years or older with clinical complaint of tinnitus and administered to five different otorhinolaryngology clinics in four different cities in our country. All participants have been tested with pure tone audiometry. Tinnitus loudness and pitch mapping were determined for all participants. All participants also interviewed individually to complete Tinnitus Handicap Inventory (THI) and asked to characterize their tinnitus symptoms using a visual analog scale (VAS) measuring severity, annoyance of tinnitus. Results: Tinnitus loudness increases significantly in the group over the age of 79, but there is no significant difference between the groups formed according to age in terms of VAS or THI values. Systemic disease does not make a significant difference that increases the severity of tinnitus. risk factors that increase tinnitus severity are included in the logistic regression analysis;High level of education and advanced age over 79 years were determined as independent risk factors. Increasing education level is an independent risk factor for increasing tinnitus severity with an odds ratio of 2.46 (95% CI, 1.080-5.624). At the same time, advanced age over 79 years is an independent risk factor with an odds ratio of 5.4 (95% CI, 1,385-21.197), which causes tinnitus severity to be felt more. Conclusion: In old age population, the incidence of tinnitus does not increase with increasing age, but tinnitus severity increases. As hearing loss increases, tinnitus severity and VAS score increase. According to the results of this study, the most important risk factors that increase the perception of tinnitus in the elderly population were determined as very advanced age and high education level. It is reasonable to think that one of the reasons for this is that the elderly in the vulnerable group for the Covid 19 pandemic should stay away from hospitals unless their tinnitus complaints are very serious. Re-performing our study in elderly individuals after the pandemic is important to see the effect of the pandemic period more clearly in these individuals.
{"title":"Multivariate Analysis of the Factors Affecting Tinnitus Severity in Old Age: A Multi-Center Cross-Sectional Study","authors":"F. Ozer, Gözde Bayramoglu Cabuk, M. Mutlu, Serap Er, Agit Simsek, S. Erbek","doi":"10.12996/gmj.2023.5","DOIUrl":"https://doi.org/10.12996/gmj.2023.5","url":null,"abstract":"Aim: The purpose of this study was to analyze the factors affecting tinnitus severity in the population aged 60 and over with a multi-central data and with multivariate analysis. Materials: This prospective study was composed of 130 subjects aged 60 years or older with clinical complaint of tinnitus and administered to five different otorhinolaryngology clinics in four different cities in our country. All participants have been tested with pure tone audiometry. Tinnitus loudness and pitch mapping were determined for all participants. All participants also interviewed individually to complete Tinnitus Handicap Inventory (THI) and asked to characterize their tinnitus symptoms using a visual analog scale (VAS) measuring severity, annoyance of tinnitus. Results: Tinnitus loudness increases significantly in the group over the age of 79, but there is no significant difference between the groups formed according to age in terms of VAS or THI values. Systemic disease does not make a significant difference that increases the severity of tinnitus. risk factors that increase tinnitus severity are included in the logistic regression analysis;High level of education and advanced age over 79 years were determined as independent risk factors. Increasing education level is an independent risk factor for increasing tinnitus severity with an odds ratio of 2.46 (95% CI, 1.080-5.624). At the same time, advanced age over 79 years is an independent risk factor with an odds ratio of 5.4 (95% CI, 1,385-21.197), which causes tinnitus severity to be felt more. Conclusion: In old age population, the incidence of tinnitus does not increase with increasing age, but tinnitus severity increases. As hearing loss increases, tinnitus severity and VAS score increase. According to the results of this study, the most important risk factors that increase the perception of tinnitus in the elderly population were determined as very advanced age and high education level. It is reasonable to think that one of the reasons for this is that the elderly in the vulnerable group for the Covid 19 pandemic should stay away from hospitals unless their tinnitus complaints are very serious. Re-performing our study in elderly individuals after the pandemic is important to see the effect of the pandemic period more clearly in these individuals.","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43189644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breast Cancer, Thyroid Cancer and Bladder Cancer in a Family with a Novel Germline Frameshift Variant SDHB c.676_677del: A Case Report","authors":"","doi":"10.12996/gmj.2023.18","DOIUrl":"https://doi.org/10.12996/gmj.2023.18","url":null,"abstract":"","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42047334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metabolic Syndrome and Cardiovascular Problems Associated with Different Types of Diet","authors":"","doi":"10.12996/gmj.2023.22","DOIUrl":"https://doi.org/10.12996/gmj.2023.22","url":null,"abstract":"","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43740543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Curriculum Development for Upper Endoscopy Training in Surgical Education","authors":"","doi":"10.12996/gmj.2023.25","DOIUrl":"https://doi.org/10.12996/gmj.2023.25","url":null,"abstract":"","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47107794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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