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Hyaluronic acid and its use in non-hormonal therapy for the treatment of vaginal atrophy and the level of awareness about the disease itself among the women from the Podkarpackie Voivodeship 玻尿酸及其在非激素治疗阴道萎缩中的应用,以及Podkarpackie省妇女对该疾病本身的认识水平
Pub Date : 2023-06-30 DOI: 10.12775/qs.2023.14.01.010
Agata Glac, Kinga Musz, Katarzyna Dobko, Gabriela Frącz, Klaudia Kuliga, Natalia Sejnowska, A. Socha, Agata Surowiec, Kinga Śnieżek, A. Zając
Introduction: Hyaluronic acid is the ingredient contained in the composition that has the ability to bind water, found in the cornea, synovial fluid and cartilage stroma. Its properties are suitable for use in an increasing range of fields, both aesthetic and in treatments focusing on the treatment of vaginal atrophy.Aim of the study: The aim of the study was to collect and analyze publications on the use of hyaluronic acid in the treatment of vaginal atrophy and assessment of the level of knowledge among women about this disease.Materials and methods: The research material was collected using an anonymous online survey. The obtained results were analyzed and verified on the basis of scientific literaturę and statistically processed using Microsoft Office Excel.Results: 59,7% of the respondents knew the term "vaginal atrophy" and 64,2% were able to correctly determine which of the hormones (estrogen) is the main cause of this condition. 59,7% of women indicated that they regularly undergo examinations and perform cytology every year, 29,9% indicated that they have examinations and visits "once in 2 years", 6% - "once in 3 years", the answers "less than once in 3 years” was given by 4,5% of the respondents. 85,7% of the surveyed women have never noticed any symptoms of vaginal atrophy and 85,9% believe that there are effective forms of treating this disorder.Conclusions: Awareness among women about vaginal atrophy, both those with medical education and women in other professions, is at a moderate level. Many women do not talk to their doctor about this not because of the feeling of shame, but also because of the lack of information and preventive measures. The progressive nature of vaginal atrophy should encourage clinicians to routinely engage in an open dialogue with patients about genitourinary health.
简介:透明质酸是角膜、滑液和软骨基质中含有的具有结合水能力的成分。它的特性适用于越来越广泛的领域,包括美学和专注于治疗阴道萎缩。研究目的:该研究的目的是收集和分析关于使用透明质酸治疗阴道萎缩的出版物,并评估妇女对这种疾病的知识水平。材料和方法:研究材料采用匿名在线调查方式收集。在科学文献的基础上对所得结果进行分析和验证,并使用Microsoft Office Excel进行统计处理。结果:59.7%的受访者知道“阴道萎缩”一词,64.2%的受访者能够正确判断哪种激素(雌激素)是导致这种情况的主要原因。59.7%的妇女表示她们每年定期接受检查和细胞学检查,29.9%的妇女表示她们“每2年一次”,6% -“每3年一次”,回答“每3年不到一次”的答复者占4.5%。85.7%的被调查妇女从未注意到阴道萎缩的任何症状,85.9%的人认为有有效的治疗这种疾病的方法。结论:无论是接受过医学教育的妇女还是从事其他职业的妇女,对阴道萎缩的认识都处于中等水平。许多妇女不与医生谈论这个问题,不是因为感到羞耻,而是因为缺乏信息和预防措施。阴道萎缩的进行性本质应该鼓励临床医生定期与患者进行关于泌尿生殖系统健康的公开对话。
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引用次数: 0
Side effects of anabolic-androgenic steroids abuse – empirical research based on anonymous surveys among people who regularly attend the gym 滥用合成代谢雄激素类固醇的副作用——基于对经常去健身房的人的匿名调查的实证研究
Pub Date : 2023-06-30 DOI: 10.12775/qs.2023.14.01.008
Monika Pająk, Kinga Grużewska-Piotrowska, Joanna Hubka, Agnieszka Grużewska
Introduction: The use of anabolic androgenic steroids is particularly common in regular gyms and fitness centres participants. AAS are usually synthetic derivatives of testosterone with anabolic and androgenic effect. However, many people, including AAS users, do not realize how many side effects they can cause.The aim of the study: The aim of the study was to assess if people who regularly attend to the gym are aware of the side effects of using anabolic steroids by empirical research based on anonymous surveys.Materials and methods: The research material was collected using an anonymous online survey in April 2023. The obtained results were analyzed and verified on the basis of scientific literature and statistically processed using Microsoft Office Excel.Results: Of the 112 gym participants, 20,5% reported using anabolic-androgenic steroids in the past. Most of the people filling the questionnaire are aware of the negative health effects of AAS use. However, most of them can't name more than 4 side effects, which shows that knowledge about AAS is still unexplored by this social group.Conclusion: The use of anabolic androgenic steroids to increase muscle size and strength is widespread. Various side effects are very common when using AAS, some of them can seriously affect the health of the users. By raising awareness of side-effects that AAS can cause, it is possible to discourage many people from using these performance-enhancing substances.Keywords: Anabolic-androgenic steroids, testosterone, gym, doping, bodybuilding
简介:合成代谢雄激素类固醇的使用在常规健身房和健身中心的参与者中尤为普遍。AAS通常是睾酮的合成衍生物,具有合成代谢和雄激素作用。然而,包括AAS使用者在内的许多人都没有意识到它们会造成多少副作用。研究目的:该研究的目的是通过基于匿名调查的实证研究来评估定期去健身房的人是否意识到使用合成代谢类固醇的副作用。资料与方法:本研究资料于2023年4月通过匿名在线调查收集。在科学文献的基础上对所得结果进行分析和验证,并使用Microsoft Office Excel进行统计处理。结果:在112名健身房参与者中,20.5%的人报告过去使用过合成代谢雄激素类固醇。大多数填写问卷的人都意识到使用原子吸收剂对健康的负面影响。然而,他们中的大多数人都不能说出4种以上的副作用,这表明这个社会群体对AAS的了解仍然不够充分。结论:广泛使用合成代谢雄激素类固醇来增加肌肉大小和力量。在使用AAS时,各种副作用是非常普遍的,其中一些会严重影响使用者的健康。通过提高对AAS可能引起的副作用的认识,有可能阻止许多人使用这些提高成绩的物质。关键词:合成代谢雄激素,睾酮,健身房,兴奋剂,健美
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引用次数: 0
Bilateral preventive mastectomy as a preventive method of breast cancer in the opinion of women 双侧预防性乳房切除术作为乳腺癌的一种预防方法在女性中得到了广泛的认同
Pub Date : 2023-06-15 DOI: 10.12775/qs.2023.14.01.005
M. Olejniczak-Nowakowska, W. Trocha, Karolina Krupa-Kotara, M. Grajek
Background Breast cancer is the most common cancer among women. Despite of the progress of medicine and develop of treatment, it is still the second couse of death among women. To reduce the risk of getting breast cancer, the more ofen teratement is "preventive mastectomies" which completely remove the breast gland by healty women that are in the "high risk" group. Material and Methods To conduct the research I develop a survey, written by my own. The study included 252 women from Poland over the age of 18. Results The opinion about the performance of preventive mastectomies in case of women in "high risk" was very diverse. Only 13% of interviewees were convinced that they would have the surgery and up to 29% could not give an answer. Most woman (86%) are convinced that breast cancer is genetically determined. That mastectomy can be a way to prevent breast cancer agrees 69% of respondents. More than half of respondents (52%) don't know if such surgery is in Poland available. Only half of the respondents could indicate the place where an examination of an increased risk of breast cancer can be made (49%). 81% of respondents examine there breasts at least with one method, and 19% did not check it at all. Conclusions The knowledge about the heredity of cancer and the availability of treatments is insufficient. Women are not convinced that they would have gone to radical preventive treatment, and they are afraid of many consequences connected with it. It is essential to educate the public including the medical stuff in this scope. It is also important that the patient together with his doctor examined all the possible options for limiting the risk of cancer.
乳腺癌是女性中最常见的癌症。尽管医学和治疗方法取得了进步,但它仍然是妇女的第二死因。为了降低患乳腺癌的风险,更常见的治疗方法是“预防性乳房切除术”,即由属于“高风险”群体的健康妇女完全切除乳腺。为了进行研究,我编写了一份调查报告。这项研究包括252名18岁以上的波兰女性。结果对“高危”女性预防性乳房切除术的实施意见不一。只有13%的受访者确信他们会做手术,高达29%的人无法给出答案。大多数女性(86%)相信乳腺癌是由基因决定的。69%的受访者同意乳房切除术是预防乳腺癌的一种方式。超过一半的受访者(52%)不知道波兰是否可以进行这种手术。只有一半的答复者能指出可以进行乳腺癌风险增加检查的地点(49%)。81%的受访者至少用一种方法检查过乳房,19%的人根本没有检查过。结论对肿瘤的遗传和治疗认识不足。妇女们不相信她们会采取激进的预防性治疗,她们害怕与之相关的许多后果。在这方面教育公众包括医务人员是必要的。同样重要的是,病人和他的医生一起检查了所有可能的选择来限制癌症的风险。
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引用次数: 0
Effect of physical activity on body weight of elementary school children 体育活动对小学生体重的影响
Pub Date : 2023-06-03 DOI: 10.12775/qs.2023.14.01.003
Patrycja Aleksy, M. Grot, Maciej Nigowski, Ewelina Sobecko, M. Grajek, Karolina Krupa-Kotara
BACKGROUND: Physical activity is an extremely important part of diet and carries a number of health-promoting benefits towards health. A distinction is made between exercise-related physical activity and spontaneous physical activity. The diet of school-aged children is of particular importance, due to the development of the body. The consequence of low physical activity with an inadequate diet generates the development of various diseases. Purpose: The purpose of this study is to evaluate the impact of physical activity on the body weight of students of elementary schools 1 and 2 in Radzionków. Material and methods: The study included 260 students of grades I-VIII of Elementary Schools Nos. 1 and 2 in Radzionków. A proprietary questionnaire addressed to the parents of the students containing questions about the students' anthropometric measurements, physical activity and eating habits was used to conduct the study. Results: Physical activity is at a high level. Most children had a normal body weight. Among the students surveyed, 71% indicated that they mainly spend their free time in active form. Students participate in swimming classes in the greatest number. Several times a week (55%) children attend extra-curricular activities. Consumption of sweets and fast food is at a low level. Eating the recommended daily serving of fruits and vegetables affects only 43% of children. Among the most commonly consumed beverages, 84% of children choose water at 1-1.5 liters per day. Conclusions: A significant part of the study group has a normal body weight, so it can be assumed that physical activity combined with appropriate eating habits has a health-promoting effect on body weight.
背景:体育活动是饮食中极其重要的一部分,对健康有许多促进健康的好处。与运动有关的身体活动和自发的身体活动是有区别的。由于身体的发育,学龄儿童的饮食尤为重要。低运动量加上不适当的饮食会导致各种疾病的发生。目的:本研究旨在评估Radzionków小学一、二年级学生体育活动对体重的影响。材料与方法:研究对象为Radzionków小学一二年级一至八年级260名学生。一份专门针对学生家长的调查问卷包含了学生的人体测量、身体活动和饮食习惯等问题。结果:身体活动处于高水平。大多数孩子的体重正常。在接受调查的学生中,71%的人表示他们主要以积极的形式度过空闲时间。参加游泳课的学生最多。每周参加几次课外活动(55%)。糖果和快餐的消费量处于较低水平。每天食用推荐量的水果和蔬菜只影响了43%的儿童。在最常饮用的饮料中,84%的儿童选择每天1-1.5升的水。结论:研究组中有相当一部分人的体重正常,因此可以认为体育活动结合适当的饮食习惯对体重有促进健康的作用。
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引用次数: 0
Multiple sclerosis - A review of recent advances in diagnostics and treatments 多发性硬化症-诊断和治疗的最新进展综述
Pub Date : 2023-06-03 DOI: 10.12775/qs.2023.14.01.004
Klaudia Wiśniewska, Agnieszka Ostańska, Adrianna Szafran, Wiktor Terelak, Marcin Ciechański, Edyta Witkowska, Laura Piasek, Grzegorz Godek, Kacper Więcław, Katarzyna Stańko
Introduction: Multiple sclerosis is a common chronic neuroinflammatory disease of the CNS with an autoimmune basis. It is the most common non-traumatic disorder that leads to disability in young adults. It occurs 3x more often in women. The quality of life of people suffering from multiple sclerosis is often significantly reduced.Objective: The purpose of this review is to analyze the latest information on the characteristics, diagnosis and treatment of patients with multiple sclerosis.Methods and matherials: A review of the literature available in the PubMed database published between 2016 and 2022, using the following keywords: "multiple sclerosis"; "pathogenesis"; "immunology"; "genetics"; “diagnostics” and "treatment."State of knowledge: Currently, there is no effective cure for multiple sclerosis but therapeutic options have increased over the past few years. Unfortunately, the effectiveness of disease-modifying therapies is too low and they cannot stop the progressive neurodegenerative process in the CNS. A recent development is the option of MS therapy using stem cells. This is to overcome the loss of nerve cells and increase the repair capacity of endogenous myelin.Conclusions: Although knowledge of the pathogenesis of the disease has advanced tremendously in recent years and many new therapeutic options have emerged, our knowledge is still incomplete. This poses a challenge for creating more drugs and halting the progression of the disease.
简介:多发性硬化症是一种常见的慢性中枢神经系统炎症性疾病,以自身免疫为基础。这是导致年轻人残疾的最常见的非创伤性疾病。女性的发病率是男性的3倍。多发性硬化症患者的生活质量通常会显著下降。目的:分析多发性硬化症的特点、诊断和治疗的最新资料。方法与材料:检索PubMed数据库2016 - 2022年间发表的文献,关键词:“多发性硬化症”;“病机”;“免疫学”;“遗传学”;诊断和治疗。知识现状:目前,多发性硬化症还没有有效的治疗方法,但在过去的几年里,治疗的选择有所增加。不幸的是,疾病改善疗法的有效性太低,它们不能阻止中枢神经系统的进行性神经退行性过程。最近的一项发展是选择使用干细胞治疗多发性硬化症。这是为了克服神经细胞的损失,增加内源性髓磷脂的修复能力。结论:尽管近年来对该疾病的发病机制有了很大的了解,并且出现了许多新的治疗选择,但我们的知识仍然不完整。这对制造更多的药物和阻止疾病的发展提出了挑战。
{"title":"Multiple sclerosis - A review of recent advances in diagnostics and treatments","authors":"Klaudia Wiśniewska, Agnieszka Ostańska, Adrianna Szafran, Wiktor Terelak, Marcin Ciechański, Edyta Witkowska, Laura Piasek, Grzegorz Godek, Kacper Więcław, Katarzyna Stańko","doi":"10.12775/qs.2023.14.01.004","DOIUrl":"https://doi.org/10.12775/qs.2023.14.01.004","url":null,"abstract":"Introduction: Multiple sclerosis is a common chronic neuroinflammatory disease of the CNS with an autoimmune basis. It is the most common non-traumatic disorder that leads to disability in young adults. It occurs 3x more often in women. The quality of life of people suffering from multiple sclerosis is often significantly reduced.\u0000Objective: The purpose of this review is to analyze the latest information on the characteristics, diagnosis and treatment of patients with multiple sclerosis.\u0000Methods and matherials: A review of the literature available in the PubMed database published between 2016 and 2022, using the following keywords: \"multiple sclerosis\"; \"pathogenesis\"; \"immunology\"; \"genetics\"; “diagnostics” and \"treatment.\"\u0000State of knowledge: Currently, there is no effective cure for multiple sclerosis but therapeutic options have increased over the past few years. Unfortunately, the effectiveness of disease-modifying therapies is too low and they cannot stop the progressive neurodegenerative process in the CNS. A recent development is the option of MS therapy using stem cells. This is to overcome the loss of nerve cells and increase the repair capacity of endogenous myelin.\u0000Conclusions: Although knowledge of the pathogenesis of the disease has advanced tremendously in recent years and many new therapeutic options have emerged, our knowledge is still incomplete. This poses a challenge for creating more drugs and halting the progression of the disease.","PeriodicalId":431915,"journal":{"name":"Quality in Sport","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133511191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Marfan’s syndrome – inheritance, diagnostic methods, management in disease 马凡氏综合征:遗传、诊断方法、疾病处理
Pub Date : 2023-05-27 DOI: 10.12775/qs.2023.14.01.001
Kinga Grużewska-Piotrowska, Monika Pająk, Joanna Hubka, Wojciech Wcisło
Introduction: Marfan’s syndrome (MFS) is a systemic, autosomal dominant connective tissue disease. It is caused mainly by the mutations in the FBN1 gene and is connected with extracellular matrix protein fibrillin-1. The incidence is about 2-3 per 10 000. About 70-75% of cases are inherited in an autosomal dominant fashion and the remaining are de-novo mutations.The aim of the study: This study aims to gather current knowledge about inheritance, diagnostic methods and management in Marfan syndrome.Materials and methods: This review was based on available data collected in the PubMed database and Google Scholar web search engine, using the key words: Marfan’s syndrome. MFS, FBN1, aortic aneurysm, Marfan FoundationConclusion: The diagnosis of Marfan’s syndrome requires detailed assessment of the body build, concomitant diseases and, above all, genetic history of the patient. Connective tissue mutations can develop at any time, and already existing defects can exacerbate. Physicians should pay particular attention while examining patients with suspected MFS. Already diagnosed patients should be checked regularly to quickly find possible complications. There is no casual treatment, multidirectional preventive therapeutic treatment is used.
马凡氏综合征(MFS)是一种全身性常染色体显性结缔组织疾病。主要由FBN1基因突变引起,与细胞外基质蛋白fibrin -1有关。发病率约为2-3 / 10000。约70-75%的病例以常染色体显性方式遗传,其余为新生突变。研究目的:本研究旨在收集马凡氏综合征的遗传、诊断方法和管理方面的最新知识。材料和方法:本综述基于PubMed数据库和Google Scholar网络搜索引擎收集的现有数据,关键词:马凡氏综合征。结论:马凡氏综合征的诊断需要详细评估患者的体质、伴发疾病,最重要的是要了解患者的遗传史。结缔组织突变可以在任何时候发生,并且已经存在的缺陷可能会恶化。医生在检查疑似MFS患者时应特别注意。已确诊的患者应定期检查,以迅速发现可能的并发症。没有随意性治疗,多方向采用预防性治疗治疗。
{"title":"Marfan’s syndrome – inheritance, diagnostic methods, management in disease","authors":"Kinga Grużewska-Piotrowska, Monika Pająk, Joanna Hubka, Wojciech Wcisło","doi":"10.12775/qs.2023.14.01.001","DOIUrl":"https://doi.org/10.12775/qs.2023.14.01.001","url":null,"abstract":"Introduction: Marfan’s syndrome (MFS) is a systemic, autosomal dominant connective tissue disease. It is caused mainly by the mutations in the FBN1 gene and is connected with extracellular matrix protein fibrillin-1. The incidence is about 2-3 per 10 000. About 70-75% of cases are inherited in an autosomal dominant fashion and the remaining are de-novo mutations.\u0000The aim of the study: This study aims to gather current knowledge about inheritance, diagnostic methods and management in Marfan syndrome.\u0000Materials and methods: This review was based on available data collected in the PubMed database and Google Scholar web search engine, using the key words: Marfan’s syndrome. MFS, FBN1, aortic aneurysm, Marfan Foundation\u0000Conclusion: The diagnosis of Marfan’s syndrome requires detailed assessment of the body build, concomitant diseases and, above all, genetic history of the patient. Connective tissue mutations can develop at any time, and already existing defects can exacerbate. Physicians should pay particular attention while examining patients with suspected MFS. Already diagnosed patients should be checked regularly to quickly find possible complications. There is no casual treatment, multidirectional preventive therapeutic treatment is used.","PeriodicalId":431915,"journal":{"name":"Quality in Sport","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128629714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Mancala Games in Human Evolution, Cultural Development, and Education: An Anthropological Inquiry 曼卡拉游戏在人类进化、文化发展和教育中的作用:一项人类学调查
Pub Date : 2023-05-27 DOI: 10.12775/qs.2023.14.01.002
Jian Zhang, Y. Liu, Zijun Yin, Safdar Abbas, Shengdong Qin
Mancala games, a diverse category of traditional board games played across cultures worldwide, bear resemblances to chess in their significance to human evolution and cultural progress. Drawing from anthropological investigations, this research uncovers the adaptability of mancala games to farming, marine, and nomadic cultures, tracing their origins to ancient Egypt and their subsequent spread among diverse civilizations in Africa, Malaysia, and China. This study highlights the extensive contributions of mancala games across various educational domains, encompassing moral, intellectual, physical, and aesthetic education, all of which foster comprehensive human development. By examining the cultural, historical, and educational dimensions of mancala games, this research unveils their profound impact on human societies throughout history, shedding light on their enduring significance. Mancala games emerge as powerful tools for promoting moral reasoning, critical thinking abilities, strategic planning skills, physical coordination, and cultural understanding. They embody cultural traditions, transmit ancestral knowledge, and foster social cohesion. Through their entertainment value and ability to shape and enrich human experiences, mancala games weave a cultural tapestry that intertwines with human societies, both past and present.  
Mancala游戏是一种不同类型的传统棋盘游戏,在世界各地的文化中都有,在人类进化和文化进步的意义上与国际象棋相似。根据人类学调查,本研究揭示了mancala游戏对农业、海洋和游牧文化的适应性,将其起源追溯到古埃及,随后在非洲、马来西亚和中国的各种文明中传播。这项研究强调了mancala游戏在各种教育领域的广泛贡献,包括道德、智力、身体和审美教育,所有这些都促进了人类的全面发展。通过考察mancala游戏的文化、历史和教育维度,本研究揭示了它们在历史上对人类社会的深远影响,揭示了它们持久的意义。Mancala游戏是促进道德推理、批判性思维能力、战略规划技能、身体协调和文化理解的强大工具。它们体现了文化传统,传递了祖先的知识,并促进了社会凝聚力。通过其娱乐价值和塑造和丰富人类体验的能力,mancala游戏编织了一幅与过去和现在的人类社会交织在一起的文化织锦。
{"title":"Role of Mancala Games in Human Evolution, Cultural Development, and Education: An Anthropological Inquiry","authors":"Jian Zhang, Y. Liu, Zijun Yin, Safdar Abbas, Shengdong Qin","doi":"10.12775/qs.2023.14.01.002","DOIUrl":"https://doi.org/10.12775/qs.2023.14.01.002","url":null,"abstract":"Mancala games, a diverse category of traditional board games played across cultures worldwide, bear resemblances to chess in their significance to human evolution and cultural progress. Drawing from anthropological investigations, this research uncovers the adaptability of mancala games to farming, marine, and nomadic cultures, tracing their origins to ancient Egypt and their subsequent spread among diverse civilizations in Africa, Malaysia, and China. This study highlights the extensive contributions of mancala games across various educational domains, encompassing moral, intellectual, physical, and aesthetic education, all of which foster comprehensive human development. By examining the cultural, historical, and educational dimensions of mancala games, this research unveils their profound impact on human societies throughout history, shedding light on their enduring significance. Mancala games emerge as powerful tools for promoting moral reasoning, critical thinking abilities, strategic planning skills, physical coordination, and cultural understanding. They embody cultural traditions, transmit ancestral knowledge, and foster social cohesion. Through their entertainment value and ability to shape and enrich human experiences, mancala games weave a cultural tapestry that intertwines with human societies, both past and present. \u0000 ","PeriodicalId":431915,"journal":{"name":"Quality in Sport","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124577743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Collagen supplementation - does it bring real benefits? 胶原蛋白补充剂-它带来真正的好处吗?
Pub Date : 2023-05-09 DOI: 10.12775/qs.2023.13.01.008
Karolina Kaziród, A. Hunek, M. Zapała, Joanna Wiśniewska-Skomra, Karolina Chmielarz, Kinga Tylutka, A. Hapon
Collagen is a protein and one of the main building blocks of our skin. It is found in bones, tendons, ligaments, internal organs, blood vessels, and the lining of the intestines. In our body, collagen enables the cohesion of tissues and organs, affects hydration, resistance and elasticity of the skin, reduces the risk of developing degenerative joint diseases. Its production decreases with age. As a result, more and more people are taking collagen supplements. It has been proven that doing so can bring many benefits to the body. Taking collagen orally can be an effective way to improve the quality of the skin, increase hydration and delay the aging process. Collagen peptides are potential therapeutic agents for treating osteoarthritis and maintaining joint health. Collagen supplementation may be an element of preventive medicine in the field of cardiovascular diseases. as it significantly reduces fat mass and increases lean mass, it also leads to lower LDL concentrations. A beneficial effect was also noted on hair and nails, as well as on brain function.
胶原蛋白是一种蛋白质,是我们皮肤的主要组成部分之一。它存在于骨骼、肌腱、韧带、内脏、血管和肠壁中。在我们的身体里,胶原蛋白能使组织和器官凝聚在一起,影响皮肤的水合作用、抵抗力和弹性,降低患退行性关节疾病的风险。它的产量随着年龄的增长而减少。因此,越来越多的人开始服用胶原蛋白补充剂。事实证明,这样做可以给身体带来很多好处。口服胶原蛋白是改善皮肤质量、增加水分和延缓衰老过程的有效方法。胶原蛋白肽是治疗骨关节炎和维持关节健康的潜在治疗剂。胶原蛋白补充可能是心血管疾病领域预防医学的一个组成部分。因为它能显著减少脂肪量,增加瘦体重,它也能降低低密度脂蛋白浓度。对头发和指甲以及大脑功能也有有益的影响。
{"title":"Collagen supplementation - does it bring real benefits?","authors":"Karolina Kaziród, A. Hunek, M. Zapała, Joanna Wiśniewska-Skomra, Karolina Chmielarz, Kinga Tylutka, A. Hapon","doi":"10.12775/qs.2023.13.01.008","DOIUrl":"https://doi.org/10.12775/qs.2023.13.01.008","url":null,"abstract":"Collagen is a protein and one of the main building blocks of our skin. It is found in bones, tendons, ligaments, internal organs, blood vessels, and the lining of the intestines. In our body, collagen enables the cohesion of tissues and organs, affects hydration, resistance and elasticity of the skin, reduces the risk of developing degenerative joint diseases. Its production decreases with age. As a result, more and more people are taking collagen supplements. It has been proven that doing so can bring many benefits to the body. Taking collagen orally can be an effective way to improve the quality of the skin, increase hydration and delay the aging process. Collagen peptides are potential therapeutic agents for treating osteoarthritis and maintaining joint health. Collagen supplementation may be an element of preventive medicine in the field of cardiovascular diseases. as it significantly reduces fat mass and increases lean mass, it also leads to lower LDL concentrations. A beneficial effect was also noted on hair and nails, as well as on brain function.","PeriodicalId":431915,"journal":{"name":"Quality in Sport","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127748146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of depression with a combination of mirtazapine and venlafaxine - a literature review 米氮平和文拉法辛联合治疗抑郁症的文献综述
Pub Date : 2023-05-09 DOI: 10.12775/qs.2023.13.01.004
Agata Szwedkowicz, Sławomir Miszuda, Sara Trojan, Urszula Fussek-Styga, Agnieszka Błaszczyk, J. Kwiecinski, Bartosz Basiaga, Krzysztof Bednarz, M. Leśniak, Jakub Heluszka
Clinical depression is a psychiatric disorder characterized by symptoms such as loss of interest and pleasure from typically enjoyable activities (anhedonia), pervasive low mood, and diminished energy leading to excessive fatigue and lower activity which have been present in a patient for at least two weeks. Available therapies consist primarily of pharmacological intervention. Indeed, some groups of medications such as SSRIs, SNRIs, TCA’s and tetracyclic antidepressants have been used to treat depression for decades, frequently in combinations. An example of such a combination is “California Rocket Fuel” composed of venlafaxine and mirtazapine Objective: To review the current literature on the efficacy of the combination of venlafaxine and mirtazapine in treating clinical depression both in drug-resistant depression and as a first-line option. To explore the risks and benefits of this choice of therapy and discuss its potential mechanism of action. Methods: Literature review of Pubmed, Google Scholar, Science Direct, and available medical textbooks.  Conclusions:Treatment with venlafaxine and mirtazapine is safe, especially for drug-resistant depression. It is worth considering adding venlafaxine to already ongoing pharmacotherapy with mirtazapine when the patient experiences sleepiness and the symptoms of depression have not been sufficiently reduced. Augmenting venlafaxine treatment with mirtazapine also seems necessary when the patient complains of insomnia. One may consider implementing such therapy as a first-line treatment in patients who suffer from depression for a long time and experience insomnia in its course.
临床抑郁症是一种精神障碍,其特征是对典型的愉快活动失去兴趣和乐趣(快感缺乏),普遍情绪低落,精力减少,导致过度疲劳和活动减少,这些症状已在患者身上出现至少两周。现有的治疗方法主要包括药物干预。事实上,一些药物,如SSRIs、SNRIs、TCA和四环抗抑郁药,已经被用于治疗抑郁症几十年了,经常是联合使用。文拉法辛与米氮平联合使用的“加州火箭燃料”就是这样一个例子。目的:回顾文拉法辛与米氮平联合使用治疗临床抑郁症的疗效,包括耐药抑郁症和作为一线治疗选择。探讨这种治疗方法的风险和益处,并讨论其潜在的作用机制。方法:查阅Pubmed、Google Scholar、Science Direct及现有医学教科书的文献资料。结论:文拉法辛联合米氮平治疗耐药抑郁症是安全的。当患者出现嗜睡和抑郁症状没有得到充分减轻时,值得考虑在已经在进行的米氮平药物治疗中加入文拉法辛。当病人抱怨失眠时,加强文拉法辛与米氮平的治疗似乎也是必要的。人们可以考虑将这种疗法作为长期患有抑郁症并在其过程中经历失眠的患者的一线治疗方法。
{"title":"Treatment of depression with a combination of mirtazapine and venlafaxine - a literature review","authors":"Agata Szwedkowicz, Sławomir Miszuda, Sara Trojan, Urszula Fussek-Styga, Agnieszka Błaszczyk, J. Kwiecinski, Bartosz Basiaga, Krzysztof Bednarz, M. Leśniak, Jakub Heluszka","doi":"10.12775/qs.2023.13.01.004","DOIUrl":"https://doi.org/10.12775/qs.2023.13.01.004","url":null,"abstract":"Clinical depression is a psychiatric disorder characterized by symptoms such as loss of interest and pleasure from typically enjoyable activities (anhedonia), pervasive low mood, and diminished energy leading to excessive fatigue and lower activity which have been present in a patient for at least two weeks. Available therapies consist primarily of pharmacological intervention. Indeed, some groups of medications such as SSRIs, SNRIs, TCA’s and tetracyclic antidepressants have been used to treat depression for decades, frequently in combinations. An example of such a combination is “California Rocket Fuel” composed of venlafaxine and mirtazapine\u0000 \u0000Objective:\u0000 \u0000To review the current literature on the efficacy of the combination of venlafaxine and mirtazapine in treating clinical depression both in drug-resistant depression and as a first-line option. To explore the risks and benefits of this choice of therapy and discuss its potential mechanism of action.\u0000 \u0000Methods:\u0000 \u0000Literature review of Pubmed, Google Scholar, Science Direct, and available medical textbooks. \u0000 \u0000Conclusions:\u0000Treatment with venlafaxine and mirtazapine is safe, especially for drug-resistant depression. It is worth considering adding venlafaxine to already ongoing pharmacotherapy with mirtazapine when the patient experiences sleepiness and the symptoms of depression have not been sufficiently reduced. Augmenting venlafaxine treatment with mirtazapine also seems necessary when the patient complains of insomnia. One may consider implementing such therapy as a first-line treatment in patients who suffer from depression for a long time and experience insomnia in its course.","PeriodicalId":431915,"journal":{"name":"Quality in Sport","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125235182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mastectomy – literature review 乳房切除术-文献回顾
Pub Date : 2023-05-09 DOI: 10.12775/qs.2023.13.01.002
Sara Trojan, Agnieszka Błaszczyk, Urszula Fussek-Styga, J. Kwiecinski, Sławomir Miszuda, Bartosz Basiaga, Krzysztof Bednarz, Agata Szwedkowicz, M. Leśniak, Jakub Heluszka
The dominant approach in the fight against breast cancer is mastectomy. Surgical operations include diagnostic, therapeutic, palliative and reconstructive procedures. The decision as to the procedure depends on the type, location and advancement of the tumor, as well as on the preferences of the patients, the skills of the operator and the availability of methods at a given centre. It is worth noting that with the increasing number of patients, there have also been significant advances in treatment, the surgical techniques used, and consequently the quality of life index has also increased. Nowadays, clinicians' attention is focused not only on the elimination of the cancer, but also on the best possible cosmetic effect of the treatment. In breast cancer, the approach to the patient should be multidisciplinary, because mastectomy and its complications affect the patient's appearance after surgery, as well as psychological aspects, changing self-perception and pain complaints.
与乳腺癌作斗争的主要方法是乳房切除术。外科手术包括诊断、治疗、缓解和重建手术。手术的决定取决于肿瘤的类型、位置和进展情况,以及患者的偏好、手术人员的技能和某一中心是否有手术方法。值得注意的是,随着患者数量的增加,治疗和使用的手术技术也有了显著的进步,因此生活质量指数也有所提高。如今,临床医生的注意力不仅集中在消除癌症上,而且还集中在治疗的最佳美容效果上。在乳腺癌中,对患者的治疗方法应该是多学科的,因为乳房切除术及其并发症会影响患者术后的外观,以及心理方面,改变自我感知和疼痛主诉。
{"title":"Mastectomy – literature review","authors":"Sara Trojan, Agnieszka Błaszczyk, Urszula Fussek-Styga, J. Kwiecinski, Sławomir Miszuda, Bartosz Basiaga, Krzysztof Bednarz, Agata Szwedkowicz, M. Leśniak, Jakub Heluszka","doi":"10.12775/qs.2023.13.01.002","DOIUrl":"https://doi.org/10.12775/qs.2023.13.01.002","url":null,"abstract":"The dominant approach in the fight against breast cancer is mastectomy. Surgical operations include diagnostic, therapeutic, palliative and reconstructive procedures. The decision as to the procedure depends on the type, location and advancement of the tumor, as well as on the preferences of the patients, the skills of the operator and the availability of methods at a given centre. It is worth noting that with the increasing number of patients, there have also been significant advances in treatment, the surgical techniques used, and consequently the quality of life index has also increased. Nowadays, clinicians' attention is focused not only on the elimination of the cancer, but also on the best possible cosmetic effect of the treatment. In breast cancer, the approach to the patient should be multidisciplinary, because mastectomy and its complications affect the patient's appearance after surgery, as well as psychological aspects, changing self-perception and pain complaints.","PeriodicalId":431915,"journal":{"name":"Quality in Sport","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115490849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Quality in Sport
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