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GATE Monte Carlo dosimetry in 90 Y TARE planning: influence of simulation parameters and image resampling on dosimetric accuracy and optimization of computational times 90 Y TARE计划中的蒙特卡罗剂量学:模拟参数和图像重采样对剂量学精度和计算时间优化的影响
IF 0.4 Q1 Arts and Humanities Pub Date : 2021-11-14 DOI: 10.1478/AAPP.992A4
D. Pistone, A. Italiano, L. Auditore, E. Amato, A. Campenní, S. Baldari
Direct Monte Carlo (MC) simulation is considered the gold standard approach for internal dosimetry in nuclear medicine, and it is increasingly used in planning Trans-Arterial Radio-Embolization (TARE) of HepatoCellular Carcinoma (HCC) {and hepatic metastases}. However its computational times, longer with respect to other simplified approaches, constitute a limiting factor, especially when dealing with {large size and finely discretized voxelized volumes}. Aim of this work was the investigation of the influence of cuts on the production of secondary particles and of input CT images resamplings on dosimetric accuracy and computational time in patient-specific voxel-level MC simulations of 90 Y-labelled glass microspheres TARE treatment, to find optimal combinations of settings for speeding up such simulations. GATE GEANT4 interface was used to perform simulations employing CT and 99m Tc SPECT as input data, examining multiple CT resolutions (via CT resamplings characterized by voxel volume factors 2, 8, and 64 with respect to native one, and a CT resampling with SPECT resolution) and production cuts (0.01 mm, 0.05 mm, 0.1 mm, 0.5 mm and some more, specific for each resampling). Increasing cut length and reducing CT resolution produces an early rapid decrease followed by a late slow decrease of simulation time as a function of this two parameters. A reduction up to 30% with respect to reference simulation time, while preserving acceptable dosimetric accuracy, was obtained. The best combination of settings among the examined ones resulted the choice of CT resampling with 8 times the native voxel volume and of 0.1-0.5 mm cut, ensuring dosimetric agreement within 1% in liver-related VOIs, while reducing simulation time to 45%.
直接蒙特卡罗(MC)模拟被认为是核医学内剂量测定的金标准方法,它越来越多地用于肝细胞癌(HCC){和肝转移}的经动脉放射栓塞(TARE)计划。然而,与其他简化方法相比,它的计算时间更长,这是一个限制因素,特别是在处理{大尺寸和精细离散的体素化体积}时。这项工作的目的是研究切割对二次粒子产生的影响,以及输入CT图像重采样对90个y标记玻璃微球TARE治疗的患者特定体素级MC模拟中剂量学精度和计算时间的影响,以找到加速此类模拟的最佳设置组合。使用GATE GEANT4接口进行模拟,使用CT和99m Tc SPECT作为输入数据,检查多个CT分辨率(通过CT重采样,其体素体积因子为2、8和64,相对于原生分辨率,CT重采样具有SPECT分辨率)和生产切割(0.01 mm、0.05 mm、0.1 mm、0.5 mm和更多,具体为每次重采样)。作为这两个参数的函数,增加切割长度和降低CT分辨率会导致模拟时间早期快速下降,随后缓慢下降。相对于参考模拟时间减少了30%,同时保持了可接受的剂量学精度。在被检查的设置中,最佳组合选择了8倍于原始体素体积和0.1-0.5 mm切割的CT重采样,确保肝脏相关voi的剂量一致性在1%以内,同时将模拟时间减少到45%。
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引用次数: 3
Transdisciplinary methods in the study of biological membranes: Laboratory learning by doing and implications for research and education 生物膜研究中的跨学科方法:实践中的实验室学习及其对研究和教育的启示
IF 0.4 Q1 Arts and Humanities Pub Date : 2021-09-30 DOI: 10.1478/AAPP.99S1A32
D. Lombardo
The investigation of the structural features in biological membranes represents a central topic in many aspects of biological science. It involves the study of the collective behavior of a great number of interacting macromolecules, while the study of the structure-function relationship requires the observation and calculation of a large number of key factors. The self-assembly processes involved in biomembranes represent the cornerstone of the biological systems functioning, due to the special role of the complex macromolecular assemblies containing lipids, proteins, carbohydrates, nucleic acids, and other active components. In this article, we describe the main techniques and approaches employed for the investigation of biological membranes under a multidisciplinary point of view. A special focus will be put on the future challenges in this academic research field and the related academic teaching programs, that must provide the integration of the different research approaches and protocols into a common scientific background based on multi- and trans-disciplinary methods that combine the expertise coming from the different disciplines. In this respect, the laboratory learning by doing can have strong implications for research and education activities, and stimulate both the scientific research community and academia to develop their skills to face the interdisciplinary challenges of modern science.
对生物膜结构特征的研究是生物科学许多方面的中心课题。它涉及到大量相互作用的大分子的集体行为的研究,而结构-功能关系的研究需要观察和计算大量关键因素。由于含有脂质、蛋白质、碳水化合物、核酸和其他活性成分的复杂大分子组装体的特殊作用,生物膜中的自组装过程代表了生物系统功能的基石。在这篇文章中,我们从多学科的角度描述了研究生物膜的主要技术和方法。将特别关注这一学术研究领域和相关学术教学计划的未来挑战,这些挑战必须基于多学科和跨学科的方法,将来自不同学科的专业知识结合起来,将不同的研究方法和协议整合到一个共同的科学背景中。在这方面,实验室边做边学可以对研究和教育活动产生强烈的影响,并激励科学研究界和学术界发展他们的技能,以应对现代科学的跨学科挑战。
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引用次数: 1
Math city map: Provide and share outdoor modelling tasks. an experience with children 数学城市地图:提供和分享户外建模任务。与孩子相处的经历
IF 0.4 Q1 Arts and Humanities Pub Date : 2021-09-30 DOI: 10.1478/AAPP.99S1A13
Angelo Ariosto, Daniela Ferrarello, M. Mammana, E. Taranto
The MathCityMap-project (MCM-Project), carried out by the IDMI Goethe- University Frankfurt (Germany), aims to provide and share outdoor modelling tasks. A web portal and a mobile app for math-trail program were created and several math-trail tasks  were designed around cities allover the world and uploaded into a system by the teachers. Then students walk the trail and its tasks by the help of mobile app or a .pdf file (generated by the web portal) to find and solve mathematical modelling tasks around the city. In this paper we present the results of an experimental teaching activity through MCM-Project for primary school students. Thanks to MCM Project, we were able to design our math-trail in Catania (Italy) and involve some 10-11 aged students in its walking. Data were gathered by means of participatory observation, video recording, interviews, and questionnaires. We will show how much this kind of activity can be effective to support primary school students in the process of modelling mathematics outside the classroom.
mathcitymap项目(MCM-Project)由德国法兰克福歌德大学IDMI开展,旨在提供和共享户外建模任务。我们创建了一个数学竞赛的门户网站和一个移动应用程序,并在世界各地的城市设计了几个数学竞赛任务,并由老师上传到一个系统中。然后,学生们通过移动应用程序或门户网站生成的pdf文件,步行路径及其任务,寻找并解决城市周围的数学建模任务。本文通过MCM-Project对小学生进行了实验教学活动。感谢MCM项目,我们能够在卡塔尼亚(意大利)设计我们的数学步道,并让一些10-11岁的学生参与其中。采用参与式观察、录像、访谈、问卷等方式收集数据。我们将展示这种活动如何有效地支持小学生在课堂外的数学建模过程。
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引用次数: 1
A flipped classroom experience: towards the knowledge of new ecofriendly materials named "geopolymers" 翻转课堂体验:了解名为“地聚合物”的新型环保材料
IF 0.4 Q1 Arts and Humanities Pub Date : 2021-09-30 DOI: 10.1478/AAPP.99S1A35
A. Mottese, F. Parisi, G. Marcianò, Fausta Giacobello, Melania Franzone, G. Sabatino, M. Bella, F. Italiano, A. Tripodo
Technological advances have impacted almost every facet of modern culture and even in the educational methodologies. As new technologies become available, they are often embraced in educational innovation in an attempt to enhance traditional instruction. To this purpose, the “flipped classroom” is a learning model in which content attainment is shifted forward to outside of class, then followed by teacher-facilitated concept application activities in class. The constructivist approach, realized through an active-learning style of teaching, is more important respect to the order with which the teacher participated in the learning process. In this respect, the goal is to provide an alternative teaching approach on environmental issue. In particular, thanks to active learning (flipped classroom) it is possible to know and to appreciate a new eco-friendly material named to “Geopolymers”. One of the most important environmental advantage that can be attributed to this material is represented by the lower energy requirements for its production. Thus, this material could represent a potential tool able to mitigate the environmental pollution. In this regard, the geopolymers could provide a possible solution to wastes reuse as a resource to scale down the demand for extraction of new resources. This paper looks at some positive aspects of technology and waste treatment, and deals with the production of innovative building materials obtained by waste recycling known as geopolymers. Specifically, it is important to highlight the possibility of using wastes characterized by high silica and aluminum amounts as raw materials, particularly suitable to produce geopolymers by chemical activation with alkali. This is a useful method to improve hazardous-waste management and to reduce health and environmental issues due to the strong capability of make inert hazardous waste. This solution confirms the importance of re-manufacturing, reusing and recycling and, moreover, making a waste a new raw material and helps to move toward a more circular economy where wastes become negligible and further natural resources are used in an efficient and sustainable way. The proposed topic is addressed to students and aims to arouse their interest in the fields of the environmental protection and waste management, but overall it gives the perspective of natural resource preservation, and a most efficient way of their use without depleting the planet’s resources.
技术进步几乎影响了现代文化的方方面面,甚至影响了教育方法。随着新技术的出现,它们往往被纳入教育创新,试图加强传统教学。为此,“翻转课堂”是一种学习模式,在这种模式中,内容获取被转移到课外,然后在课堂上由教师推动概念应用活动。建构主义教学法是通过积极的学习方式来实现的,更重要的是教师参与学习过程的顺序。在这方面,目标是提供一种关于环境问题的替代教学方法。特别是,多亏了积极的学习(翻转课堂),才有可能了解和欣赏一种名为“地质聚合物”的新型环保材料。这种材料最重要的环境优势之一是其生产所需的能源较低。因此,这种材料可以代表一种潜在的工具,能够减轻环境污染。在这方面,地质聚合物可以为废物作为资源的再利用提供一种可能的解决方案,以减少对新资源开采的需求。本文着眼于技术和废物处理的一些积极方面,并涉及通过废物回收获得的创新建筑材料的生产,即地质聚合物。具体而言,重要的是要强调使用二氧化硅和铝含量高的废物作为原料的可能性,特别适合通过碱化学活化生产地质聚合物。由于制造惰性危险废物的能力很强,这是一种改进危险废物管理和减少健康和环境问题的有用方法。这一解决方案证实了再制造、再利用和回收的重要性,此外,还将废物作为新的原材料,有助于朝着更循环的经济发展,使废物变得微不足道,并以高效和可持续的方式利用更多的自然资源。提议的主题是针对学生的,旨在激发他们对环境保护和废物管理领域的兴趣,但总的来说,它提供了保护自然资源的视角,以及在不消耗地球资源的情况下最有效地利用自然资源的方式。
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引用次数: 2
Study of the oscillations of drops of newtonian liquids induced by acoustic vibrations 声学振动引起牛顿液体液滴振荡的研究
IF 0.4 Q1 Arts and Humanities Pub Date : 2021-09-30 DOI: 10.1478/AAPP.99S1A23
Ferdinando Catalano, Antonio Cerza, Filippo Invernizzi, Sonia Migliavacca, Elio Scholtz, G. Castorina
The aim of this paper is to verify the applicability of the Rayleigh-Lamb equation to drops having different diameters and, specifically, with diameters of the order of magnitude of centimeters (macro drops), millimeters or micrometers (micro drops). On this purpose three experiments have been taken into account. A completely new fact is constituted by the following question: it is possible to apply the Rayleigh-Lamb equation to a heterogeneous drop like that represented by a soap bubble, characterized by a surface tension different from the substance constituting the drop’s mass (air)? The results reported in this paper seem to confirm that this is possible. The order of magnitude of the calculated autofrequencies is comparable to that observed experimentally. The limitations of the experiments are the geometry of the system. The Rayleigh-Lamb equation applies, strictly speaking, to a free drop not subjected to the action of external forces. This would be possible through the use of special devices, i.e the Acoustical Levitated. Therefore, it was decided to carry out the experiments with drops bound by viscous adhesion to the respective supports. It is evident that the geometry of the drop is no longer perfectly spherical, however the results obtained do not seem to have suffered greatly from this limitation.
本文的目的是验证瑞利-兰姆方程对具有不同直径的液滴的适用性,特别是直径为厘米(大液滴)、毫米或微米(微液滴)数量级的液滴。为此,已经考虑了三个实验。以下问题构成了一个全新的事实:是否可以将瑞利-兰姆方程应用于由肥皂泡表示的非均匀液滴,其特征是表面张力不同于构成液滴质量的物质(空气)?本文报告的结果似乎证实了这是可能的。计算的自频率的数量级与实验观察到的自频率相当。实验的局限性在于系统的几何形状。严格地说,瑞利-兰姆方程适用于不受外力作用的自由液滴。这可以通过使用特殊设备实现,即声学悬浮装置。因此,决定用通过粘性粘附到相应支撑物上的液滴进行实验。很明显,液滴的几何形状不再是完美的球形,然而所获得的结果似乎没有受到这种限制的很大影响。
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引用次数: 1
Artefacts teach-math. the meaning construction of trigonometric functions 文物教数学。三角函数的意义构造
IF 0.4 Q1 Arts and Humanities Pub Date : 2021-09-30 DOI: 10.1478/AAPP.99S1A15
A. Serpe, M. G. Frassia
Trigonometry is an area of the high school mathematics curriculum strictly related to algebraic, geometric, and graphical reasoning. In spite of its importance to both high school and advanced mathematics, research has shown that trigonometry remains a difficult topic for both students and teachers. A new approach the teaching of trigonometry – calibrated for the 21 st century - opens the question of the place and nature of trigonometry in contemporary high school mathematics. In this prospective, the authors have carried out a study aimed at explaining connections between research and teaching practice of trigonometric functions emphasizing conceptual understanding, multiple representation and connections, mathematical modelling, and mathematical problem-solving. This paper shows a teaching approach for meaning construction of trigonometric functions with the aid of technological artefacts.
三角学是高中数学课程中与代数、几何和图形推理紧密相关的一个领域。尽管它对高中数学和高等数学都很重要,但研究表明,三角函数对学生和教师来说仍然是一个困难的话题。一种面向21世纪的三角教学新方法,提出了三角在当代高中数学中的地位和性质问题。有鉴于此,作者开展了一项研究,旨在解释三角函数研究与教学实践之间的联系,强调概念理解、多重表示和联系、数学建模和数学解决问题。本文提出了一种利用技术人工制品进行三角函数意义建构的教学方法。
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引用次数: 2
What can we learn from large-scale surveys about our students learning of maths? 我们能从关于学生学习数学的大规模调查中学到什么?
IF 0.4 Q1 Arts and Humanities Pub Date : 2021-09-30 DOI: 10.1478/AAPP.99S1A4
G. Bolondi
Large-scale surveys on Maths and Science learning (such as OCSE-Pisa, IE-TIMMS, TIMMS Advanced and the INVALSI in Italy) have a strong influence on public opinion in all countries and, in a top-down process, on decisions by policy-makers and administrative stakeholders, organization of the education system, official curricula, actual curricula, and the didactic choices of teachers. This process is activated principally by a mechanism of comparison and ranking which is implicit in the published results of these surveys – a mechanism which induces effects which are not always positive (such as teaching to test). This study sets out to show, with some examples from the ongoing research, how it is possible to analyse macro-phenomena revealed by the survey results with conceptual tools of mathematics education, in order to look beyond the statistical data of individual students’ performances or of the sample group as a whole. The quantitative analytical tools used in processing the information collected in these surveys can be used to suggest valuable clues in understanding the nature and origins of common misconceptions and difficulties, and how these are linked with didactic practices. The first case that we consider regards the answering of questions which highlight a strong difference between male and female students (the so-called gender gap): which questions are these and why? The second case is the analysis of some INVALSI questions through which it is possible to quantify a well-known didactic phenomenon: the “loss of meaning” in algebra. The second case regards the answering of questions which highlight a strong difference between male and female students (the so-called gender gap): which questions are these and why? The third case that we present shows how it is possible to study how students’ behaviour (and their ability to find problem-solving strategies, for example) is influenced by the layout and wording of the question. These and other examples show how mathematics education can greatly benefit from the use of mixed methods (quantitative/qualitative) in surveys and research.
关于数学和科学学习的大规模调查(如OCSE-Pisa、IE-TIMMS、TIMMS Advanced和意大利的INVALSI)对所有国家的公众舆论都有很大的影响,并且在一个自上而下的过程中,对决策者和行政利益相关者的决策、教育系统的组织、官方课程、实际课程和教师的教学选择都有很大的影响。这一过程主要是由一种比较和排名机制激活的,这种机制隐含在这些调查公布的结果中,这种机制导致的影响并不总是积极的(比如教考试)。本研究旨在通过正在进行的研究中的一些例子,展示如何用数学教育的概念工具分析调查结果所揭示的宏观现象,以便超越个别学生的表现或整个样本组的统计数据。在处理这些调查中收集的信息时使用的定量分析工具可用于提供有价值的线索,以了解常见误解和困难的性质和起源,以及这些误解和困难如何与教学实践联系起来。我们考虑的第一个案例是关于突出男女学生之间的巨大差异(所谓的性别差距)的问题的答案:哪些问题是这样的,为什么?第二种情况是对一些INVALSI问题的分析,通过这些问题有可能量化一个众所周知的教学现象:代数中的“意义丧失”。第二种情况是关于回答那些突出男女学生之间的巨大差异(所谓的性别差距)的问题:哪些问题是这样的,为什么?我们提出的第三个案例表明,如何有可能研究学生的行为(以及他们找到解决问题策略的能力,例如)是如何受到问题的布局和措辞的影响的。这些和其他例子表明,在调查和研究中使用混合方法(定量/定性)可以极大地受益于数学教育。
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引用次数: 2
Evolution of the concept of force in modern nanoscience: The perspectives of the experiential learning in research and teaching programs 现代纳米科学中力概念的演变:研究和教学项目中体验式学习的视角
IF 0.4 Q1 Arts and Humanities Pub Date : 2021-09-30 DOI: 10.1478/AAPP.99S1A30
D. Lombardo, L. Pasqua, M. Kiselev
Modern society requires to efficiently identify the new trends in sustainable development and their implications in future science, research and education. One of the major challenges in nanotechnology is the education and training of a new generation of skilled workers, that request the improvement of student understanding of the concept of force within the more broad scenery of modern nanoscience. The recent advancement in nanoscience and nanotechnology evidences the powerful methods of supramolecular approaches in modern nanoscience, which are based on the complex combinations of different forces acting both at the molecular and supramolecular levels. These forces represent the driving interactions for the efficient assembly of building blocks, and for the development of highly functional materials and devices with novel properties. Herein, a review of the evolution of the concept of force in connection with modern aspect of nanotechnology is presented. A special focus is devoted to the development of modern approaches taken from the academic research programs, that allows a fruitful understanding of the myriad of scientific discoveries that have characterized these last years. In this respect, the experiential learning method can be properly designed and delivered, with particular respect to the use of bio- and nanotechnology, and in ways that help the learners to efficiently develop the knowledge and skills needed in the modern age.
现代社会需要有效地确定可持续发展的新趋势及其对未来科学、研究和教育的影响。纳米技术的主要挑战之一是新一代技术工人的教育和培训,这要求学生在现代纳米科学更广阔的背景下提高对力概念的理解。纳米科学和纳米技术的最新进展证明了超分子方法在现代纳米科学中的强大作用,这种方法是基于分子和超分子水平上不同力的复杂组合。这些力量代表了驱动的相互作用,以有效地组装构建模块,并为开发具有新特性的高功能材料和设备。在此,回顾了力的概念的演变与纳米技术的现代方面提出。一个特别的重点是致力于从学术研究项目中获得的现代方法的发展,这使得对过去几年的无数科学发现有了富有成效的理解。在这方面,体验式学习方法可以适当地设计和提供,特别是在生物和纳米技术的使用方面,并以帮助学习者有效地发展现代所需的知识和技能的方式。
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引用次数: 1
The relevance of interdisciplinary research activities on synthesis and characterization of ceramics for medical application 医学应用陶瓷合成和表征跨学科研究活动的相关性
IF 0.4 Q1 Arts and Humanities Pub Date : 2021-09-30 DOI: 10.1478/AAPP.99S1A27
Amani Khaskhoussi
Replacement of damaged tissues by biomaterials after a disease or injury is one of the most interesting challenge in medical science. The proper approach in developing a new biomaterial for a specific application must include the evaluation of all aspects and available knowledge in the different fields of science necessary for a comprehensive understanding of the behavior of the new component (e.g. a prosthetic implant) in a special environment (the human body). Starting from chemistry to know how to synthesize our material passing to physics and mechanics to understand how our material will act when stressed, going to biology to discover the reaction of the human body against this material and using mathematics to model and optimize our complex systems. In this concern, this paper reported an interdisciplinary approach used in developing a new material for biomedical application. The importance of the development of innovative teaching methods was also deeply discussed.
在疾病或损伤后用生物材料替代受损组织是医学科学中最有趣的挑战之一。为特定应用开发新生物材料的正确方法必须包括对不同科学领域的所有方面和可用知识的评估,以便全面了解新组件(例如假体植入物)在特殊环境(人体)中的行为。从化学开始,了解如何合成我们的材料,再到物理和力学,了解我们的材料在压力下的行为,再到生物学,发现人体对这种材料的反应,并用数学来建模和优化我们的复杂系统。在这方面,本文报道了一种跨学科方法用于开发生物医学应用的新材料。并对创新教学方法的重要性进行了深入探讨。
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引用次数: 0
Towards a historical approach to physics education 探索物理教育的历史方法
IF 0.4 Q1 Arts and Humanities Pub Date : 2021-09-30 DOI: 10.1478/AAPP.99S1A1
E. Giannetto
Modern physics is a complex multiplicity of practices: theoretical, mathematical, experimental and simulation practices. Experimental and simulation practices are related to the pragmatic dimension of a physical theory. Mathematical practices are related to the syntactic dimension of a physical theory, but theoretical practices involve an often neglected semantic dimension. Physics and consequently teaching physics are usually reduced to the syntactic and pragmatic dimensions. Semantic dimension is linked to the conceptualization of the physical reality, to the conception of Nature. By neglecting the semantic dimension, physics is reduced to a pure mathematical game and to technological manipulations. Thus, the cultural aspect of science is lost and physics education is reduced to a mere technical training. This process of de-culturalization of science had its roots in the Enlightenment’s turn in physics to free it from theology and metaphysics and had its completion in the post-second-world-war era. I believe we have to recover the cultural aspects of physics to understand it more deeply in its whole complexity. We have to recover all its relationships with other disciplines as philosophy, mathematics, psychology, sociology and other sciences, even theology, which are fundamental to constitute its semantic dimension. Historical approach to physics and physics education is the only way to recover this interdisciplinarity at the roots of the various physical conceptions of Nature. In this way, for example, we can understand that beyond mechanics there is a mechanist conception of Nature, beyond thermodynamics there is a thermodynamical conception of Nature, and beyond electromagnetism there is an electromagnetic conception of Nature. These different conceptions of Nature are not compatible and their historical fight has produced the relativistic, quantum and chaos revolutions in XX century physics. These different conceptions of Nature imply different existential self-understanding of the meaning of mankind in the universe and different ethical perspectives.
现代物理学是一个复杂的多重实践:理论、数学、实验和模拟实践。实验和模拟实践与物理理论的实用维度有关。数学实践与物理理论的句法维度有关,但理论实践涉及一个经常被忽视的语义维度。物理和物理教学通常被简化为句法和语用两个维度。语义维度与物理现实的概念化,与自然的概念相联系。由于忽略了语义维度,物理学被简化为纯粹的数学游戏和技术操纵。这样,科学的文化方面就丧失了,物理教育就沦为单纯的技术训练。这种科学去文化化的过程,其根源在于启蒙运动将物理学从神学和形而上学中解放出来,并在二战后的时代完成。我相信我们必须恢复物理学的文化方面,以便更深入地理解它的整个复杂性。我们必须恢复它与其他学科的关系,如哲学、数学、心理学、社会学和其他科学,甚至神学,这是构成它的语义维度的基础。对物理学和物理教育采取历史方法是恢复这种跨学科性的唯一途径,这种跨学科性是各种自然物理概念的根源。例如,通过这种方式,我们可以理解,在力学之外,有一个机械论的自然概念,在热力学之外,有一个热力学的自然概念,在电磁学之外,有一个电磁学的自然概念。这些不同的自然观是不相容的,它们之间的历史斗争产生了二十世纪物理学的相对论、量子和混沌革命。这些不同的自然观隐含着对人类在宇宙中存在意义的不同的自我认识和不同的伦理观点。
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引用次数: 1
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