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The prevalence of mental disorders in patients with posterior segment eye disease 后段眼病患者精神障碍的患病率
Pub Date : 2023-07-05 DOI: 10.17816/nb303671
Denis A. Jakovlev, Anna D. Shurygina, S. Kuzmina, A. Rascheskov
The article presents materials from foreign and domestic literature, that indicate the relationship between ophthalmic pathology and mental disorders. The most common mental disorders are depression and anxiety among patients with visual impairment. The prevalence of comorbidity of ophthalmic and mental pathology was considered, as well as factors contributing to the progression of these diseases.
本文介绍了国内外有关眼科病理与精神障碍关系的文献资料。视觉障碍患者中最常见的精神障碍是抑郁和焦虑。考虑了眼科和精神病理共病的患病率,以及导致这些疾病进展的因素。
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引用次数: 0
Clinical and social aspects of the quality of life in patients with Parkinson’s disease 帕金森病患者生活质量的临床和社会方面
Pub Date : 2023-07-05 DOI: 10.17816/nb321228
L.I. Kopylova, Alexey A. Tappakhov, T. Nikolaeva, T. Popova
Parkinsons disease (PD) is an age-related neurodegenerative disease associated with the loss of dopamine-producing neurons in the substantia nigra. The disease is manifested by motor disorders and a variety of non-motor symptoms (NMS). NMS may reduce the quality of life (QoL) of people with Parkinsons disease (PD) more than motor manifestations, but their ultimate contribution has not been fully established. AIM. To determine the impact of motor, cognitive and affective disorders and social factors on the quality of life of patients with PD in the Republic of Sakha (Yakutia). MATERIAL AND METHODS. The study included 35 patients with PD, HoehnYahr stage 13 (60% women and 40% men), mean age 64.42.0 years. We used scales: UPDRS, MoCA, HADS, NMSQuest, Epward Sleepiness Scale, PDQ39. The analysis of clinical signs and social factors in the studied group of patients was carried out. RESULTS. The decrease in QoL was moderately associated with disease stage (r=0.56, p=0.009), the severity of motor manifestations (r=0.65, p 0.001) and the total number of NMS (r=0.46, p=0.008). Age and disease duration did not affect on QoL. The decrease in QoL was influenced by the presence of depression (r=0.83, p 0.001), anxiety (r=0.69, p 0.001) and cognitive decline (r=0.46, p=0.008). Low levels of QoL were found in individual PD patients and in people with disabilities. QoL was not influenced by ethnicity, gender, employment or education. Three groups of patients with PD were identified: those with mild, moderate and severe decrease in QoL. Their clinical and social portraits are presented. CONCLUSION. The dependence of the quality of life of patients with PD on the form of the disease, the stage of the disease, the severity of depression, social factors has been demonstrated, which requires attention not only from neurologists, but also from psychotherapists and social workers.
帕金森病(PD)是一种与年龄相关的神经退行性疾病,与黑质中产生多巴胺的神经元的丧失有关。该病表现为运动障碍和多种非运动症状(NMS)。NMS可能比运动表现更能降低帕金森病(PD)患者的生活质量(QoL),但其最终贡献尚未完全确定。的目标。确定运动、认知和情感障碍及社会因素对萨哈共和国(雅库特)PD患者生活质量的影响。材料和方法。该研究纳入35例PD, HoehnYahr期13(60%女性,40%男性)患者,平均年龄64.42.0岁。我们使用的量表:UPDRS, MoCA, HADS, nmquest, Epward嗜睡量表,PDQ39。对研究组患者的临床症状及社会因素进行分析。结果。生活质量的降低与疾病分期(r=0.56, p=0.009)、运动表现严重程度(r=0.65, p 0.001)和NMS总次数(r=0.46, p=0.008)有中度相关性。年龄和病程对生活质量无影响。生活质量下降受抑郁(r=0.83, p= 0.001)、焦虑(r=0.69, p= 0.001)和认知能力下降(r=0.46, p=0.008)的影响。个体PD患者和残疾人的生活质量较低。生活质量不受种族、性别、就业或教育的影响。将PD患者分为轻度、中度和重度生活质量下降组。他们的临床和社会肖像呈现。结论。PD患者的生活质量依赖于疾病的形式、疾病的阶段、抑郁的严重程度、社会因素,这不仅需要神经学家的关注,也需要心理治疗师和社会工作者的关注。
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引用次数: 0
Longitudinal study of coping strategies in first-time stroke patients: association with cognitive dysfunction, stroke site and depression 首次脑卒中患者应对策略的纵向研究:与认知功能障碍、脑卒中部位和抑郁的关系
Pub Date : 2023-07-05 DOI: 10.17816/nb253252
M. Savina, Elisaveta A. Petrova, Eugenia A. Koltsova
BACKGROUND. Inadequate coping strategies are associated with affective disorders and poor quality of life in stroke survivors. Although coping strategies are determined by several non-modifiable factors they have been shown to change over time. AIM. Longitudinal assessment of coping strategies and associated factors in patients with first-ever stroke. MATERIAL AND METHODS. This study was a part of prospective observational study of a cohort of patients with first-ever stroke. Patients underwent standard psychiatric, neurological and cognitive assessment and CT. Patients without aphasia, severe fatigue, eye problems fulfilled the coping strategies indicator (Amirkhan J.H., 1990): 87 patients in the first week after stroke, 45 patients in the second week, 20 patients in 3 months, 21 patients in 6 months, 33 patients in 1 year after stroke. Non-parametric statistics were used. RESULTS. Different coping strategies were not determined by age, gender and severity of neurological deficit; there were some correlations with educational level, work status, cognitive dysfunction, stroke volume and lesion location. There were differences in the use of coping strategies in the groups with different depression manifestations: in the group with depression manifestations in the early recovery period and later, coping strategies did not differ from the control group in the acute stroke period, but since the manifestation of depression the amount of avoidance strategies increased. In the group with pre-stroke depression, a significant increase in avoidance strategies was observed in the first week after the stroke. CONCLUSIONS. The longitudinal study of coping strategies revealed that the use of coping strategies is a dynamic process determined by several modifiable and non-modifiable factors in combination. Coping strategies were not predictors of depression; on the contrary, depression seems to influence the choice of coping strategies.
背景。不适当的应对策略与卒中幸存者的情感障碍和生活质量差有关。尽管应对策略是由几个不可改变的因素决定的,但它们已被证明会随着时间的推移而改变。的目标。首次脑卒中患者应对策略及相关因素的纵向评估。材料和方法。本研究是首次中风患者队列前瞻性观察研究的一部分。患者接受标准的精神病学、神经学和认知评估以及CT检查。无失语、严重疲劳、眼病的患者满足应对策略指标(Amirkhan J.H., 1990):卒中后第一周87例,第二周45例,3个月20例,6个月21例,1年33例。采用非参数统计。结果。不同的应对策略不受年龄、性别和神经功能障碍严重程度的影响;与受教育程度、工作状态、认知功能障碍、脑卒中量和病变部位有一定的相关性。不同抑郁表现组在应对策略的使用上存在差异:急性脑卒中恢复期早期和后期抑郁表现组的应对策略与对照组无显著差异,但自抑郁表现以来,回避策略的数量有所增加。在卒中前抑郁组中,卒中后第一周观察到回避策略的显著增加。结论。应对策略的纵向研究表明,应对策略的使用是一个动态的过程,是由若干可改变因素和不可改变因素共同决定的。应对策略不是抑郁的预测因子;相反,抑郁似乎会影响应对策略的选择。
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引用次数: 0
“Semantic void” of some of psychiatric terms used in the diagnosis of schizophrenia 精神分裂症诊断中使用的一些精神病学术语的“语义空白”
Pub Date : 2023-07-05 DOI: 10.17816/nb397614
V. Mendelevich
The article is devoted to an analysis of the terminology used to support a psychiatric diagnosis. Using linguistic approaches, the author draws attention to the presence in psychiatry of semantically filled and semantically empty terms that denote certain psychopathological symptoms/signs. It is concluded that for a number of terms used in the diagnosis of schizophrenia spectrum disorders, a revision should be revised and those that are vague, ambiguous, not included in international diagnostic systems and recognised as archaic should be removed from the psychiatric lexicon. In particular, we are talking about symptoms such as emasculation of emotions, pretentiousness, paradoxicality, eccentricity, ambivalence.
这篇文章专门分析用于支持精神病诊断的术语。使用语言学方法,作者提请注意精神病学中语义填充和语义空白术语的存在,这些术语表示某些精神病理症状/体征。结论是,对于精神分裂症谱系障碍诊断中使用的一些术语,应该进行修订,那些含糊不清、模棱两可、不包括在国际诊断系统中并被认为是过时的术语应该从精神病学词典中删除。具体来说,我们讨论的症状包括情感的阉割,自命不凡,矛盾,古怪,矛盾心理。
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引用次数: 2
How misunderstanding the principles and limitations of evidence-based medicine may discredit the concept 误解循证医学的原则和局限性会如何使这一概念失去信誉
Pub Date : 2023-07-05 DOI: 10.17816/nb321817
N. A. Zorin
The discussion on the methodological limitations of the quasi- measurement of human feelings and sensations, started by the author in the journal Neurology bulletin, continues. There are a number of reasons for accepting/rejecting and understanding the principles and limitations of clinical epidemiology/evidence-based medicine (EBM) to the point of deliberate distortion. It is shown that the ideas of freedom and creativity in medicine, are ways of avoiding control and the realization of biopower. A concrete example, the study of the efficacy of antidepressants, shows how it is possible, either unintentionally or intentionally, to obtain a false result without following the principles and tenets of EBM.
由作者在《神经病学公报》杂志上开始的关于人类情感和感觉的准测量方法局限性的讨论仍在继续。接受/拒绝和理解临床流行病学/循证医学(EBM)的原则和局限性的原因有很多,以至于故意歪曲。研究表明,医学中的自由和创造性思想是避免控制和实现生物权力的途径。一个具体的例子,对抗抑郁药功效的研究表明,如果不遵循循证医学的原则和原则,无论有意无意,都有可能得到错误的结果。
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引用次数: 0
Probability of change in diagnosis among adult patients diagnosed with childhood mental disorders 儿童期精神障碍成年患者诊断改变的概率
Pub Date : 2023-07-05 DOI: 10.17816/nb340868
Timur R. Gazizullin, V. Mendelevich
BACKGROUND. The problem of changing a psychiatric diagnosis is a reality. AIM. To study the frequency and probability of changing the exposed patient at the age of psychiatric illness when moving under the supervision of a psychiatrist served by a large population. MATERIAL AND METHODS. We analyzed 246 cases of patients who first applied to a psychiatrist in childhood (adolescence), then taken for consultative or dispensary registration. The study was follow-up in nature, was carried out with the help of the analysis of electronic databases of the RCPB. acad. V.M. Bekhterev of the Ministry of Health of the Republic of Tatarstan (Kazan), as well as by studying primary medical documentation (outpatient cards and case histories). The results of the study were processed on the basis of Statistica 6.0 and MS Excel 2020. RESULTS. The main variants of the outcomes of mental disorders diagnosed in childhood of patients are described. It is shown that in more than half of clinical cases the confirmation of a psychiatric diagnosis at an early age is not final, and the issue of further diagnostic search remains unresolved and requires revision. Using the methods of multifactorial statistics, the main transnosological (dimensional) models of algorithms for the development of mental disorders are modeled.
背景。改变精神病诊断的问题已经成为现实。的目标。目的:研究在精神科医生的监督下,在大量人群中更换暴露患者的频率和概率。材料和方法。我们分析了246例患者,他们首先在儿童(青春期)向精神科医生申请,然后进行咨询或药房登记。这项研究是在对皇家保护儿童委员会电子数据库进行分析的帮助下进行的,属于后续性质。鞑靼斯坦共和国(喀山)卫生部的V.M. Bekhterev博士,以及通过研究基本医疗文件(门诊卡和病历)。研究结果采用Statistica 6.0软件和MS Excel 2020软件进行处理。结果。描述了儿童时期诊断的精神障碍结果的主要变体。研究表明,在超过一半的临床病例中,早期精神病诊断的确认并不是最终的,进一步的诊断研究问题仍未解决,需要修订。利用多因子统计的方法,建立了精神障碍发展的主要跨医学(维度)算法模型。
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引用次数: 0
Satisfaction with life as a compliance factor of patients with schizophrenia 生活满意度是精神分裂症患者的依从性因素
Pub Date : 2023-07-05 DOI: 10.17816/nb397585
V. Ruzhenkova, I. S. Khamskaya, K. Retyunskiy, A. V. Boeva, O.V. Zhigulina
BACKGROUND. One of the main problems of patients in a psychiatric clinic is non-compliance with the order of treatment, which leads to frequent exacerbations of the disease and social exclusion. According to some reports, about 3050% of patients completely refuse treatment after hospitalization or take medications in reduced doses. Important among the factors affecting the compliance of patients with schizophrenia are the patients personal characteristics, the severity of symptoms, criticism of the disease, substance abuse, side effects of drugs, features of therapeutic cooperation and other factors. AIM was to analyse the relationship between life satisfaction and compliance in patients with schizophrenia. MATERIAL AND METHODS. We examined 157 patients diagnosed with Schizophrenia aged 23 to 52 years (38.58.1 years). The examination was carried out one week before discharge from the hospital. The main methods of the study were clinical-psychopathological, clinical-dynamic, psychometric (DAI-10 compliance scale, Q-LES-Q-SF test for assessing the degree of satisfaction with life, Beck hopelessness scale, hospital anxiety and depression scale HADS), and statistical (descriptive statistics, 2 test with Yates correction for contingency tables 22, correlation analysis Spearmans rank correlation coefficient). RESULTS. It was found that only 11.4% of males and 20.7% of females were fully compliant. A third of the men and half of the women took medication under the supervision of relatives. Only 12.6% of patients with schizophrenia were satisfied with their lives (without gender differences). A significant proportion of patients (43.3%) experienced a feeling of dissatisfaction with life, and males are 2 times more likely than women. Also, some patients at the time of discharge overestimated their mood, which did not correspond to the subjective assessment. Severe depression, anxiety and a sense of hopelessness increased the patients dissatisfaction with all parameters of everyday life. Compliance of patients directly depends on their mood, ability to work, perform everyday household duties and relationships with others, which becomes problematic with anxiety, depression and a sense of hopelessness. CONCLUSION. Compliance is directly correlated with the quality of life, satisfaction with it, the physical condition of the patient, favourable family relationships, good mood, availability and job satisfaction.
背景。精神病诊所患者的主要问题之一是不遵守治疗顺序,这导致疾病频繁恶化和社会排斥。根据一些报道,约有3050%的患者在住院后完全拒绝治疗或服用减少剂量的药物。影响精神分裂症患者依从性的重要因素有患者的个人特征、症状的严重程度、对疾病的批评、药物滥用、药物的副作用、治疗合作的特点等因素。目的分析精神分裂症患者生活满意度与依从性的关系。材料和方法。我们检查了157例23至52岁(38.58.1岁)的精神分裂症患者。检查是在出院前一周进行的。研究的主要方法有临床-精神病理学、临床-动态、心理测量(DAI-10依从性量表、Q-LES-Q-SF生活满意度评定量表、Beck绝望量表、医院焦虑抑郁量表HADS)和统计学(描述性统计、Yates校正列联表2检验、Spearmans秩相关系数相关分析)。结果。调查发现,只有11.4%的男性和20.7%的女性完全遵守规定。三分之一的男性和一半的女性在亲戚的监督下服药。只有12.6%的精神分裂症患者对生活感到满意(无性别差异)。相当比例的患者(43.3%)对生活感到不满,男性的可能性是女性的2倍。此外,一些患者在出院时高估了自己的情绪,这与主观评估不相符。严重的抑郁、焦虑和绝望感增加了患者对日常生活所有参数的不满。患者的依从性直接取决于他们的情绪、工作能力、履行日常家务的能力以及与他人的关系,这将成为焦虑、抑郁和绝望感的问题。结论。依从性与生活质量、满意度、患者的身体状况、良好的家庭关系、良好的心情、可用性和工作满意度直接相关。
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引用次数: 0
Spontaneus resolution of syringomyelia is a rare variant of the disease course: analysis of clinical and neuroimaging descriptions 脊髓空洞的自发性消退是一种罕见的疾病变体:临床和神经影像学描述分析
Pub Date : 2023-05-10 DOI: 10.17816/nb119898
E. Mendelevich, Ch. S. Nurullina
The cases of syringomyelia described in the literature with spontaneous collapse of the cavity are analyzed. Differences among patients with cavity decay in childhood and adults are assessed. The basic theories of cavity shedding in syringomyelia are presented in this article.
对文献中描述的空洞自发塌陷的病例进行了分析。评估儿童和成人蛀牙患者的差异。本文介绍了脊髓空洞脱落的基本理论。
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引用次数: 0
Impulsive aggression: recognition and choice of pharmacotherapy 冲动性攻击:药物治疗的认知与选择
Pub Date : 2023-05-10 DOI: 10.17816/nb119902
E. V. Snedkov
Instrumental (controlled) aggression is observed in populations of both mentally healthy and mentally ill people. This type of aggression is not associated with any specific pathophysiological changes and cannot be considered as an independent symptom, which might be a target of pathogenetic therapy. By contrast, impulsive aggression is a paroxysm of anger, based on affectively narrowed consciousness when volition control is significantly reduced or absent. Impulsivity is different from cognate compulsivity by the loss of a stage of intellectual processing of affectively painted representations and by that the irrational attraction to action is realized involuntary, automatic. All impulsive-behavior patients are united by common pattern of neurobiological abnormalities, such as deficit of frontal inhibition of subcortical unconscious emotions and inclinations in response to relevant arousing stimuli. The results from evidence-based research, meta-analyses and Cochrane reviews of efficiency of pharmacological agents used for reduction of impulsive aggressive behavior were summarized.
工具性(控制性)攻击在精神健康人群和精神疾病人群中都可以观察到。这种类型的攻击与任何特定的病理生理变化无关,不能被视为一种独立的症状,这可能是病理治疗的目标。相比之下,冲动攻击是一种愤怒的发作,是在意志控制明显减少或不存在的情况下,基于情感上的意识狭窄。冲动性与同源强迫性的不同之处在于失去了对情感描绘的表征进行智力处理的阶段,并且对行为的非理性吸引是无意识地、自动地实现的。所有冲动行为患者都有共同的神经生物学异常模式,如皮层下无意识情绪的额叶抑制缺陷和对相关唤醒刺激的反应倾向。综述了循证研究、荟萃分析和Cochrane综述对减少冲动性攻击行为的药物效果的研究结果。
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引用次数: 0
Psychological characteristics of IT workers with different professional tasks 不同职业任务IT工作者的心理特征
Pub Date : 2023-05-10 DOI: 10.17816/nb119894
Aisa V. Paskenova, E. V. Makaricheva, L. Fatkhutdinova
The study involved 99 IT-workers who were divided into 4 subgroups depending on the content of the job: 3 groups of professional IT-workers system administrators, software developers, product supporters (62 people), and a group of office workers (37 people). The neurotic state questionnaire by Yakhin and Mendelevich, the Pittsburgh sleep questionnaire, as well as a questionnaire on socio-demographic indices were used. Software developers showed a significant tendency to neurotic depression and reactions of hysterical type compared with the other groups. This was related with both the personal characteristics of the workers, and the content and organization of work. For the other two subgroups of professional IT-workers, characterological features played a more important role in the development of neurotic states than the content of the job.
这项研究涉及99名it工作者,他们根据工作内容分为4个小组:3组专业it工作者系统管理员、软件开发人员、产品支持者(62人)和一组办公室工作人员(37人)。采用Yakhin和mendeleich的神经状态问卷、匹兹堡睡眠问卷和社会人口指数问卷。与其他组相比,软件开发人员表现出明显的神经质抑郁和歇斯底里型反应倾向。这既与工人的个人特征有关,也与工作的内容和组织有关。对于其他两个专业it工作者亚组,性格特征在神经症状态发展中的作用比工作内容更重要。
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引用次数: 0
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Neurology Bulletin
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