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Ischemic Colitis induced by COVID-19: A Case Report COVID-19致缺血性结肠炎1例
IF 0.4 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-30 DOI: 10.21649/akemu.v28i1.5007
U. Rabbani, Abdulrhman Aldukhayel, Abdulhamid F. Alresheedi
COVID-19 has been associated with coagulation disorders which add further to the morbidity and mortality caused by the disease itself. Ischemic colitis can result from hypercoagulable states. In this report we present a rare case of ischemic colitis induced by COVID-19 in 27-year-old male. Patient presented with severe generalized abdominal pain. CT abdomen showed filling defects, absent enhancement indicating venous bowel ischemia. CT-angiograph revealed complete thrombosis of portal, splenic, superior and inferior mesenteric veins. Patient was shifted to intensive care unit and kept nothing per orum. He was given Heparin, tramadol and paracetamol intravenously. COVID-19 Reverse transcription–polymerase chain reaction (RT–PCR) was positive. He was then given Favipiravir through nasogastric (NG) tube. On 4th day NG was removed and patient was subsequently discharged on 9th day. COVID-19 may lead to hypercoagulable states and gastrointestinal complications. COVID-19 patients with gastrointestinal symptoms should be evaluated carefully for possible ischemia.
COVID-19与凝血功能障碍有关,这进一步增加了疾病本身引起的发病率和死亡率。缺血性结肠炎可由高凝状态引起。在此报告中,我们报告了一例罕见的由COVID-19引起的缺血性结肠炎,患者为27岁男性。病人表现为严重的全身腹痛。腹部CT显示充盈缺损,强化缺失提示静脉性肠缺血。ct血管造影显示门静脉、脾静脉、肠系膜上、下静脉血栓形成。病人被转移到重症监护室,没有留下任何东西。静脉注射肝素、曲马多和扑热息痛。新冠病毒逆转录聚合酶链反应(RT-PCR)阳性。然后通过鼻胃管给予法匹拉韦。第4天取出NG,患者于第9天出院。COVID-19可能导致高凝状态和胃肠道并发症。有胃肠道症状的COVID-19患者应仔细评估是否存在缺血。
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引用次数: 0
Immediate Psychological Impact of COVID 19 Pandemic on Mental Health of Pediatric Healthcare Workers COVID - 19大流行对儿科医护人员心理健康的直接心理影响
IF 0.4 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-30 DOI: 10.21649/akemu.v28i1.5018
S. Ijaz, I. Ijaz
Background: COVID-19 pandemic has been effecting the world since December, 2019. Front line healthcare professionals faced increased stress level while dealing with overload of patients. Hence it triggered feelings of loneliness, despair and physical mental fatigue. Objective: To determine the immediate psychological impact of COVID-19 pandemic on mental health of pediatric healthcare workers by using Depression Anxiety Stress scoring scale, DASS-21 scale. Methods: This cross-sectional online survey was conducted from 1st July to 30th November 2020 in the department of Pediatric Medicine Unit II, King Edward Medical University/Mayo Hospital, Lahore. A 21-item Depression Anxiety Stress scoring scale was circulated online among Healthcare workers of Teaching hospitals of Lahore. These included Pediatric Specialists, General Physicians, Postgraduate Trainees in Paeds Medicine, House Officers in Paeds Medicine and Pediatric Nurses. 150 Healthcare workers (HCWs) participated. Responses were analyzed with SPSS V.26. Results: Out of 150 healthcare workers, 101(67.3%) were falling in the range of 20-30 years, 76(50.7%) were females, 81(54%) were singles, maximum 59(39.3%) were postgraduate trainees and majority 65(43.4%) had
背景:2019年12月以来,COVID-19大流行影响全球。一线医护人员在处理超负荷的病人时面临着越来越大的压力。因此,它引发了孤独、绝望和身心疲劳的感觉。目的:采用抑郁焦虑压力量表(DASS-21)评估新冠肺炎大流行对儿科医护人员心理健康的直接影响。方法:本横断面在线调查于2020年7月1日至11月30日在拉合尔爱德华国王医科大学/梅奥医院儿科医学第二单元进行。在拉合尔教学医院的医护人员中在线分发了21项抑郁焦虑压力评分量表。其中包括儿科专家、普通内科医生、儿科医学研究生实习生、儿科医学住院医生和儿科护士。共有150名医护人员参与。采用SPSS V.26对应答进行分析。结果:150名卫生工作者中,年龄在20 ~ 30岁之间的有101人(67.3%),女性76人(50.7%),单身81人(54%),研究生59人(39.3%)最多,本科毕业65人(43.4%)居多
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引用次数: 0
Histopathological Grading and Staging of Invasive Ductal Carcinoma in Modified Radical Mastectomy Specimens 乳腺改良根治术中浸润性导管癌的组织病理学分级和分期
IF 0.4 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-30 DOI: 10.21649/akemu.v28i1.5004
Q. Javaid, F. Kamal, M. Iqbal, Rahat Sarfaraz, Asmaa Qureshy, R. Basharat
Background: Breast carcinoma is the most common malignancy in females associated with high mortality rate. Objective: The purpose of present study was to describe the histological grade and histopathological stage of invasive ductal carcinoma of breast among female patients and to determine the association of tumor size and histological grade withnodal metastasis. Methods: This is an analytical cross sectional study, conducted in the Department of Pathology Fatima Jinnah Medical University Lahore, Pakistan from September, 2019 till February, 2020. Female patients of all age groups who were diagnosedwith invasive ductal carcinoma and underwent modified radical mastectomy were included in the study. Tissue processed and Hematoxylin and Eosin staining was performed. All the sections were examined under the light microscope by myself and two other consultant pathologists independently. Histological grading of invasive ductal carcinoma was done by following Modified Scarff Bloom Richardson grading system and histopathological staging was done according to CAP protocols. Results: Total of 60 female patients diagnosed with invasive ductal carcinoma were included in the present study. Mean age of the patient calculated was 48.17± 13.12 years with age range from 26 to 90 years. Size of the tumor ranged from 1cm to 10cm. On microscopy, histological grade III was the most frequent grade (36, 60%). Out of total 60 cases n=43(71.6%) were diagnosed with regional lymph node metastasis and T2N1Mx( 17,38.3%) was the most frequent stage of the tumor. Statistically no significant association of tumor size and histological grade was observed with regional lymph node metastasis (p >0.05).
背景:乳腺癌是女性最常见的恶性肿瘤,死亡率高。目的:探讨女性乳腺浸润性导管癌的组织学分级和病理分期,探讨肿瘤大小和组织学分级与淋巴结转移的关系。方法:这是一项分析性横断面研究,于2019年9月至2020年2月在巴基斯坦拉合尔法蒂玛真纳医科大学病理系进行。所有年龄组诊断为浸润性导管癌并行改良根治性乳房切除术的女性患者均被纳入研究。组织处理后进行苏木精和伊红染色。所有切片均由本人和另外两名病理顾问医师在光镜下独立检查。浸润性导管癌按改良Scarff Bloom Richardson分级系统进行组织学分级,按CAP方案进行组织病理学分期。结果:共纳入60例确诊为浸润性导管癌的女性患者。患者平均年龄为48.17±13.12岁,年龄26 ~ 90岁。肿瘤大小从1cm到10cm不等。在显微镜下,组织学III级是最常见的级别(36.60%)。60例患者中有43例(71.6%)被诊断为区域淋巴结转移,T2N1Mx(17例,38.3%)是最常见的肿瘤分期。肿瘤大小、组织学分级与区域淋巴结转移无统计学意义(p >0.05)。
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引用次数: 0
Comparison of Anterior and Posterior Kaltenborn Grade III Glide on Glenohumeral Joint for Improving External Rotation in Adhesive Capsulitis (Frozen Shoulder) 肩关节前、后Kaltenborn III级滑动改善粘连性囊炎(冻结肩)患者外旋效果的比较
IF 0.4 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-30 DOI: 10.21649/akemu.v28i1.5012
A. Asif, Amna Zia, S. Liaqat, F. Afzal
Background: Adhesive capsulitis is a common disabling and painful condition that causes limitation of both passive and active ranges of shoulder joint. Division of frozen shoulder can be into primary and secondary categories. Different techniques have been devised in physiotherapy to regain limited range of motion in adhesive capsulitis. Objectives: To compare the effects of anterior and posterior grade III Kaltenborn glides on glenohumeral joint for improving external rotation and functional ability in patients with adhesive capsulitis. Material and methods: This randomized controlled trial was conducted in University of Health Sciences, Lahore and 40 patients were recruited from Mayo Hospital, Lahore from 08-10-2019 to 10-02-2020 and divided randomly into two groups. Group A was given anterior glide and Group B was given posterior glide. Treatment was given for 4 weeks, 3 sessions in each week. Outcomes were measured in terms of external rotation and functional status of shoulder from Goniometry and SPADI scale. Results: Comparison of External rotation and SPADI score of group A (Anterior glider) and group B (posterior glide) has shown that both groups were similar at baseline (p>0.05 for all variables) but post-treatment mean external rotation range in group A was 36.50 ± 7.72 while in group B was 52.80 ± 7.14, with the P value
背景:粘连性肩关节囊炎是一种常见的致残和疼痛疾病,可导致肩关节被动和主动活动范围受限。肩周炎可分为原发性和继发性两类。不同的技术已设计在物理治疗中,以恢复有限的活动范围,在粘连性囊炎。目的:比较前后III级Kaltenborn滑梯对粘连性囊炎患者肩关节外旋和功能的影响。材料与方法:本随机对照试验在拉合尔健康科学大学进行,于2019年10月8日至2020年2月10日在拉合尔梅奥医院招募40例患者,随机分为两组。A组采用前滑行法,B组采用后滑行法。治疗4周,每周3次。根据角度测量和SPADI量表测量外旋和肩关节功能状态。结果:比较A组(前滑翔机)和B组(后滑翔机)的外旋和SPADI评分,两组在基线时相似(所有变量p>0.05),但治疗后A组的平均外旋范围为36.50±7.72,B组为52.80±7.14,p值差异无统计学意义
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引用次数: 0
Intolerance of Uncertainty and Anxiety Sensitivity as Prospective Risk Factors for Cyberchondria in Undergraduate Students 不确定性不耐受和焦虑敏感性是大学生网络疑病的前瞻性危险因素
IF 0.4 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-30 DOI: 10.21649/akemu.v28i1.4993
Zubaida Rashid, Mommana Ali Rathore, I. Khushk, Syed Fawad Mashhadi, Moneeba Ahmed, Muhammad Shahzeb
Background: Researchers have discovered a vicious loop of increased physical health concerns and online medical information seeking known as "cyberchondria," despite the benefits of widely accessible medical information on the Internet. Despite proposed theoretical models of cyberchondria, research on risk factors for the development ofcyberchondria is lacking in our setup. Anxiety sensitivity and intolerance of uncertainty are two potential risk factors.Objective: This study was conducted to determine the frequency of health related internet researches i.e cyberchondria and to locate and find association between the resultant health anxiety and intolerance of uncertainty among the medical andnon-medical students of different institutions of Islamabad and Rawalpindi. Methods: A cross-sectional study was conducted on a total of 300 students of medical and engineering universities between ages of 18 and 25 from October 2019 to March 2020 by using Cyberchondria Severity Scale, intolerance of uncertainty scale and anxiety sensitivity index scale questionnaires as data collection tool. Data collected was statistically analyzed by SPSSversion-22. Results: Out of 300 participants, 169 (56.3%) students were found positive for cyberchondria and 131 (43.7%) were found negative and majority of the positive participants were medical students. Results revealed significant association between intolerance of uncertainty (0.567, p < 0.000) as well as Anxiety sensitivity (0.805, p < 0.000) and cyberchondria among the medical and non-medical students of Islamabad and Rawalpindi.Conclusions: The current study's findings show that both Anxiety sensitivity and intolerance of uncertainty may have a role in the development of cyberchondria especially in medical students. 
背景:研究人员发现,尽管在互联网上广泛获取医疗信息是有好处的,但人们对身体健康的担忧和在线医疗信息的搜索却形成了一个恶性循环,即“网络疑病症”。尽管提出了网络疑病的理论模型,但对网络疑病发展的危险因素的研究在我们的设置是缺乏的。焦虑、敏感和对不确定性的不耐受是两个潜在的危险因素。目的:本研究旨在确定伊斯兰堡和拉瓦尔品第不同院校的医学生和非医学生中与健康相关的互联网研究(即网络疑病症)的频率,并定位和发现由此产生的健康焦虑与对不确定性的不容忍之间的关系。方法:采用《网络疑病严重程度量表》、《不确定性不耐受量表》和《焦虑敏感性指数量表》问卷作为数据收集工具,对2019年10月至2020年3月共300名年龄在18 ~ 25岁的医学和工程类高校学生进行横断面研究。收集的数据用SPSSversion-22进行统计分析。结果:300名受访学生中,网络疑病阳性169人(56.3%),阴性131人(43.7%),以医学生居多。结果显示,伊斯兰堡和拉瓦尔品第医科学生和非医科学生的不确定性不耐受度(0.567,p < 0.000)和焦虑敏感性(0.805,p < 0.000)与网络疑病有显著相关。结论:目前的研究结果表明,焦虑敏感性和对不确定性的不耐受可能在网络疑病症的发展中起作用,特别是在医学生中。
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引用次数: 1
Assessment of Parental Satisfaction with Day-Care Surgical Services in a Tertiary Level Pediatric Hospital 某三级儿科医院日托外科服务家长满意度评价
IF 0.4 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-30 DOI: 10.21649/akemu.v28i1.5003
R. Ahmed, Jamshed Akhtar, Naima Zamir, S. Taqvi, Safia Bibi
Background: Parental feedback is important for improving quality of the surgical services provided.Objective: This study was conducted to assess the level of satisfaction of parents with the day-care surgical services so as to find out where improvement is needed. Methods: This was an observational cross sectional study conducted in the Department of Pediatric Surgery, National Institute of Child Health, Jinnah Sindh Medical University Karachi from September 2019 to April 2020. The parents of the children who underwent different day-care surgical procedures were included. A validated Parent Satisfaction Scale (PSS) which consist of 11-items was used. The responses were made according to Likert scale. Three groups of satisfied, undecided and unsatisfied study participants were made according to the scores obtained. The socio-demographic variables including age of parents and children, level of education, and income group were compared amongst study groups. Results: Total of 114 parents participated. The most common procedure performed was inguinal herniotomy (n=59). Seven (6%) patients were brought back after discharge due to pain. Eighty-seven (76.30%) parents were satisfied with the services provided while 18 (15.8%) were unsatisfied and 9 (7.9%) undecided. A significant difference in the satisfaction level of the study participants noted with respect to the mean age of parents (p=0.039), level of education (p< 0.001) and income groups (p< 0.001). Conclusion: Majority of the study participants were satisfied with the surgical services provided. Lack of respect given by the hospital staff and delay in getting treatment were the main reasons for dissatisfaction. Socio-demographic characteristics of the study participants were significantly associated with the level of satisfaction.
背景:家长反馈对提高外科服务质量非常重要。目的:本研究旨在评估家长对日托外科服务的满意度,以找出需要改善的地方。方法:这是一项观察性横断面研究,于2019年9月至2020年4月在卡拉奇真纳信德医科大学国家儿童健康研究所儿科外科进行。这些儿童的父母接受了不同的日托手术。采用经验证的家长满意度量表(PSS),共11项。采用李克特量表进行问卷调查。根据获得的分数分为满意、不满意和不满意三组。社会人口学变量包括父母和子女的年龄、教育水平和收入群体在研究组之间进行比较。结果:共114名家长参与调查。最常见的手术是腹股沟疝切开术(n=59)。7例(6%)患者因疼痛出院后复诊。87名家长(76.30%)对所提供的服务感到满意,18名家长(15.8%)不满意,9名家长(7.9%)不确定。研究参与者的满意度在父母的平均年龄(p=0.039)、教育水平(p< 0.001)和收入群体(p< 0.001)方面存在显著差异。结论:大多数研究参与者对所提供的手术服务感到满意。医院工作人员对患者缺乏尊重和延误治疗是患者不满的主要原因。研究参与者的社会人口学特征与满意度水平显著相关。
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引用次数: 0
System within System: World Health Organization Building Blocks and Public-Private Partnership in Healthcare sector of Pakistan 系统中的系统:世界卫生组织在巴基斯坦医疗保健部门的基石和公私伙伴关系
IF 0.4 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-30 DOI: 10.21649/akemu.v28i1.4989
S. Afzal, Amber Arshad
"Health systems" (also called "health care systems" and "healthcare systems") are organizations that provide health care services to target populations by integrating people, institutions, and resources. A health care system is nothing more than a collection of interdependent pieces and their relationships. People, organizations, and behaviors whose primary goal is to promote, restore, or maintain health are part of a "health system." This system relies on the interdependence of its various components. Numerous components that make up a health care system, like patients, families, communities, health departments, health care professionals, and organizations responsible for funding health care are just a few examples. The duties and functions of each component are intertwined. WHO proposes supporting and building a health care system based on the following framework, the Six Health System Building Blocks? It is possible to produce more equitable and long-lasting gains in health services and outcomes by enhancing the six components of the health system and 1 managing their interrelationships .
“卫生系统”(也称为“卫生保健系统”和“卫生保健系统”)是指通过整合人员、机构和资源向目标人群提供卫生保健服务的组织。卫生保健系统只不过是相互依赖的部分及其关系的集合。以促进、恢复或维持健康为主要目标的人、组织和行为是“卫生系统”的一部分。这个系统依赖于它的各个组成部分的相互依赖。组成卫生保健系统的众多组成部分,如患者、家庭、社区、卫生部门、卫生保健专业人员和负责资助卫生保健的组织,只是其中的几个例子。每个组成部分的职责和功能是相互交织的。世卫组织建议根据以下框架支持和建立卫生保健系统,即六个卫生系统构建模块?通过加强卫生系统的六个组成部分和管理它们之间的相互关系,就有可能在卫生服务和成果方面取得更公平和持久的成果。
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引用次数: 0
Factors Associated with Early and Late Initiation of Antiretroviral Therapy among People Living with Human Immunodeficiency Virus in Lahore, Pakistan 巴基斯坦拉合尔人类免疫缺陷病毒感染者早期和晚期开始抗逆转录病毒治疗的相关因素
IF 0.4 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-30 DOI: 10.21649/akemu.v28i1.5014
K. Junaid, S. Muzaffar, R. Nazim, Amber Arshad, Amjad Khan, Hina Zubair
Background: Despite the availability of antiretroviral therapy (ART), HIV is still responsible for substantial illness and death, especially in developing countries. Early start of treatment (ART) is associated with better therapeutic outcome, reduced transmissibility of HIV, reduction in loss to follow-up, and remarkably reduced death rate. Objectives: To find out the factors associated with early and late Initiation of ART among patients affected by HIV in Lahore, Pakistan Methods: From November 2017 to April 2018, researchers conducted an analytical cross-sectional study on 156 HIV patients aged 18 and older that began antiretroviral therapy (ART) at Jinnah & Mayo Hospital, Lahore's HIV clinics. Samples were selected by non-probability convenience sampling and Univariate and multivariate analyses were performed to assess factors related to early and late Initiation of ART. The p-value of less than
背景:尽管有抗逆转录病毒治疗(ART),艾滋病毒仍然是造成大量疾病和死亡的原因,特别是在发展中国家。早期开始治疗(ART)与更好的治疗结果、降低艾滋病毒传播率、减少随访损失和显著降低死亡率相关。方法:2017年11月至2018年4月,研究人员对156名18岁及以上在拉合尔真纳和梅奥医院艾滋病毒诊所开始抗逆转录病毒治疗(ART)的艾滋病毒患者进行了一项分析性横断面研究。采用非概率方便抽样方法选取样本,进行单因素和多因素分析,评估早期和晚期开始抗逆转录病毒治疗的相关因素。的p值小于
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引用次数: 0
Positive Predictive Value of Computed Tomography Virtual Laryngoscopy in Detecting Laryngeal Carcinoma Taking Histopathology as Gold Standard 以组织病理学为金标准的计算机断层虚拟喉镜对喉癌的阳性预测价值
IF 0.4 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-30 DOI: 10.21649/akemu.v28i1.4992
Nawaz Rashid, Aliya Noreen, I. H. Dogar, A. Mansoor, K. Hashmi, Fareeha Nawaz
Background: Computed tomography virtual laryngoscopy (CTVL) is favored diagnostic tool in detecting laryngeal carcinoma because it delivers excellent temporal and spatial resolution. Objective: To determine the positive predictive value of computed tomography virtual laryngoscopy in detecting laryngeal carcinoma taking histopathology as gold standard. Methods: A cross sectional survey was conducted at department of Radiology, Mayo Hospital Lahore. The completion of study was done in six months [Feb 16, 2019 till Aug 16, 2019]. After obtaining approval from ethical committee and informed consent from subjects, 64 subjects were included in the study who presented in the Department of the Radiology having carcinoma of larynx on CTVL and then sent to department of ENT of mayo hospital, where they underwent direct laryngoscopy and afterwards biopsy obtained sent to the department of histopathology. All the subjects undergoing CT scan examination on the CT machine of hospital. Contrast injection was given to all subjects undergoing CT scan, through power injector at the rate of 4ml per min and dosage of 0.1ml/kg. Same machine was used to conduct all CT scans and was inferred through same radiologist and all the histopathology was performed by same pathologist to exclude bias. Results: The mean age of patients was 44.38 ± 9.57 years with minimum and maximum age as 22 and 60 years. There were 47(73.4%) male and 17(26.6%) female cases. On histopathology the laryngeal carcinoma was diagnosed in 56(87.5%) of the cases while it was negative in 8(12.5%) of the cases. On CT the laryngeal carcinoma was diagnosed in 59(92.2%) of the cases while it was negative in 5(7.8%) of the cases. The Positive Predictive Value of CT was 89.83%, while its sensitivity was 94.64%, specificity was 25.00%, negative predictive value was 40.00% and diagnostic accuracy was 85.94%. Conclusion: Through the findings of this study it is concluded that positive predictive value of computed tomography virtual laryngoscopy is high (89.83%) in detecting laryngeal carcinoma taking histopathology as gold standard. CT is a precise and non-invasive imaging method in detecting laryngeal carcinoma. 
背景:计算机断层扫描虚拟喉镜(CTVL)因其具有良好的时间和空间分辨率而成为检测喉癌的首选诊断工具。目的:探讨以组织病理学为金标准的计算机断层扫描虚拟喉镜对喉癌的阳性预测价值。方法:对拉合尔梅奥医院放射科进行横断面调查。研究在6个月内(2019年2月16日至2019年8月16日)完成。经伦理委员会批准并获得受试者知情同意后,64名患者在CTVL喉癌放射科就诊,送往梅奥医院耳鼻喉科,行直接喉镜检查,活检后送组织病理学。所有受试者均在医院CT机上接受CT扫描检查。所有接受CT扫描的受试者均注射造影剂,注射速度为4ml / min,剂量为0.1ml/kg。使用同一台机器进行所有CT扫描,并由同一名放射科医生推断,所有组织病理学均由同一名病理学家进行,以排除偏差。结果:患者平均年龄44.38±9.57岁,最小年龄22岁,最大年龄60岁。男性47例(73.4%),女性17例(26.6%)。组织病理学诊断为喉癌56例(87.5%),阴性8例(12.5%)。CT检查发现喉癌59例(92.2%),阴性5例(7.8%)。CT阳性预测值为89.83%,敏感性为94.64%,特异性为25.00%,阴性预测值为40.00%,诊断准确率为85.94%。结论:通过本研究发现,以组织病理学为金标准,计算机断层扫描虚拟喉镜对喉癌的检测阳性预测值较高(89.83%)。CT是一种精确、无创的喉癌诊断方法。
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引用次数: 0
Vitamin D Deficiency in Acute Myocardial Infarction and its Association with Diabetes 急性心肌梗死的维生素D缺乏及其与糖尿病的关系
IF 0.4 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-30 DOI: 10.21649/akemu.v28i1.5005
Muhammad Khawar Saeed, Asadullah Khan kakar, A. Z. K. Chachar, Afshan Khanum, H. Khan
Background: Vitamin D deficiency is a global public health problem. Vitamin D deficiency is linked to a number of non skeletal major chronic diseases like cardiovascular disease.Objectives: To determine the frequency of vitamin D deficiency in patients presenting with ST segment elevated myocardial infarction. Methods: During the study period, 150 patients fulfilling the selection criteria of ST segment elevation Myocardial infarction were included in this study. A blood sample for 25-hydroxyl vitamin D level was drawn for each patient. Vitamin D deficiency was defined as less than or equal to 20g/dl. Vitamin D deficiency was stratified with demographics such as age, gender, and Comorbids such as smoking and Diabetes. Results: The mean age of the patients was 51.6±6.7 years. There were 80 (53.3%) male and 70 (46.7%) female patients. There were 52 (34.7%) smokers and 55 (36.7%) patients had diabetes mellitus as Comorbids. The mean serum vitamin D level was 23.46±0.82 ng/ml. Sixty-four patients (49.3%) had vitamin D deficiency with levels below 20ngml, while another 46(30.6%) had insufficient Vitamin D levels in ranges of 21-30ng/ml. There was no association of age, gender, smoking or Diabetes history with vitamin D deficiency (p value >90.05 for all these variables). Conclusion: Vitamin D deficiency is present in over half of patients with ST elevated Myocardial infarction. Only 20% of patients with acute myocardial infarction had normal vitamin D values, with remaining having insufficient levels. The deficiency was not associated with gender, age, or comorbidity such as smoking or Diabetes. 
背景:维生素D缺乏是一个全球性的公共卫生问题。维生素D缺乏与许多非骨骼主要慢性疾病,如心血管疾病有关。目的:确定ST段抬高型心肌梗死患者维生素D缺乏的频率。方法:选取研究期间符合ST段抬高型心肌梗死选择标准的患者150例。为每位患者抽取25-羟基维生素D水平血样。维生素D缺乏被定义为低于或等于20克/分升。维生素D缺乏症根据年龄、性别和合并症(如吸烟和糖尿病)进行分层。结果:患者平均年龄51.6±6.7岁。男性80例(53.3%),女性70例(46.7%)。吸烟52例(34.7%),合并糖尿病55例(36.7%)。血清维生素D水平平均值为23.46±0.82 ng/ml。64名患者(49.3%)缺乏维生素D,水平低于20ng /ml,而另外46名患者(30.6%)维生素D水平不足,水平在21-30ng/ml之间。年龄、性别、吸烟、糖尿病史与维生素D缺乏无相关性(p值>90.05)。结论:半数以上ST段升高的心肌梗死患者存在维生素D缺乏。只有20%的急性心肌梗死患者维生素D值正常,其余患者维生素D水平不足。这种缺乏与性别、年龄或合并症(如吸烟或糖尿病)无关。
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引用次数: 0
期刊
Annals of King Edward Medical University Lahore Pakistan
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