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Paramedian Forehead Flap in Large Nasal Skin Defects: Twenty-years' Experience. 旁位前额皮瓣治疗鼻大面积皮肤缺损:二十年经验。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-09-01 Epub Date: 2022-11-15 DOI: 10.4274/tao.2022.2021-12-9
Fazıl Apaydın, İsa Kaya, Mustafa Uslu, Veysel Berber

Objective: Skin cancers occur most commonly in the head and neck region where the nose is the most commonly affected unit. The nose is the part of the face that is most exposed to trauma, sunlight, and other environmental factors. From the aesthetic and functional point of view, reconstruction of the defects occurring after skin cancer removal creates a great challenge for the surgeon. In this retrospective study, we present the success rates achieved in the past 20 years with paramedian forehead flaps used for repairing large defects of the nose.

Methods: The study included 62 patients who underwent paramedian forehead flap due to nasal skin tumor [basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)] in Ege University Faculty of Medicine Otolaryngology Department between 2000 and 2020. Data on follow-up time, patients' age and gender, defect sizes, and tumor types were obtained retrospectively from patient files, histopathologic examination results and patient photographs. Additional diseases such as diabetes, hypertension, and coronary artery disease that could affect flap success, were noted.

Results: Out of 62 patients 29 (46.8%) were female and 33 (53.2%) were male. Their mean age was 61.4 (range: 46-88) years. Mean follow-up period was 125.6 (8-244) months. Of the 62 patients 33 (53.2%) were operated on for BCC and 29 (46.8%) for SCC. Four patients (6.5%) had recurrences during their follow-up. There was no loss of the paramedian forehead flap.

Conclusion: Paramedian forehead flap is a reliable option in the reconstruction of larger defects of the nose even in smokers and elderly patients who have comorbid diseases.

目的:皮肤癌最常见于头颈部,其中鼻子是最常见的受累部位。鼻子是脸部最容易受到外伤、阳光和其他环境因素影响的部位。从美学和功能的角度来看,皮肤癌切除后缺损的重建对外科医生来说是一个巨大的挑战。在这一回顾性研究中,我们介绍了在过去的20年里,用旁位前额皮瓣修复鼻子的大缺陷的成功率。方法:选取2000 - 2020年在埃格大学医学院耳鼻喉科因鼻皮肤肿瘤[基底细胞癌(BCC)和鳞状细胞癌(SCC)]行旁位前额皮瓣治疗的62例患者。从患者档案、组织病理学检查结果和患者照片中回顾性获得随访时间、患者年龄和性别、缺陷大小、肿瘤类型等数据。其他疾病如糖尿病、高血压和冠状动脉疾病也可能影响皮瓣的成功。结果:62例患者中,女性29例(46.8%),男性33例(53.2%)。平均年龄为61.4岁(范围:46-88岁)。平均随访125.6(8-244)个月。62例患者中,33例(53.2%)行BCC手术,29例(46.8%)行SCC手术。随访期间有4例(6.5%)复发。额旁瓣无缺损。结论:旁位前额皮瓣是修复较大鼻部缺损的一种可靠的选择,即使对吸烟者和有其他合并症的老年患者也是如此。
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引用次数: 0
Effects of the Lunar Cycle, Seasons and the Meteorological Factors on Peripheral Vertigo. 月周期、季节及气象因子对周边眩晕的影响。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-09-01 Epub Date: 2022-11-15 DOI: 10.4274/tao.2022.2022-6-12
Mehtap Koparal, Emine Elif Altuntaş, Cüneyt Yılmazer, Erman Altunışık, Mehmet Karataş

Objective: This study aimed to determine whether peripheral vertigo is related to the lunar cycle, the seasons, or meteorological factors, in patients who presented to the ear, nose, and throat clinic.

Methods: All the patients, diagnosed with vertigo between January 2020 and January 2022, were identified through a retrospective review of our hospital database. The clinical and demographic data of the patients were recorded. Daily humidity (minimum, average, and maximum; %), daily temperature (minimum, average, and maximum; °C), daily average and maximum wind speed (m/min), daily air pressure (minimum and average maximum; hPa) and wind direction (degrees) values were noted. Also, the phases of the moon, i.e., first quarter, new moon, last quarter, and full moon periods were determined.

Results: A total of 5,432 patients were included in the study. No statistically significant differences were noted among them with respect to the lunar cycle (p=0.233). However, patient density was found to increase in the winter months.

Conclusion: This study concluded that the frequency of diseases is related to meteorological factors, nonetheless, no statistical relationship was found between the lunar cycle and the frequency of patient entries.

目的:本研究旨在确定在耳鼻喉门诊就诊的患者中,周围性眩晕是否与月亮周期、季节或气象因素有关。方法:通过回顾性分析我院数据库,确定所有在2020年1月至2022年1月期间诊断为眩晕的患者。记录患者的临床及人口学资料。日湿度(最小、平均、最大值);%),日温度(最低、平均、最高);°C),日平均和最大风速(m/min),日气压(最小和平均最大值;hPa)和风向(度)值。此外,还确定了月相,即第一季度,新月,最后季度和满月时期。结果:共纳入5432例患者。在月球周期方面,他们之间没有统计学上的显著差异(p=0.233)。然而,发现患者密度在冬季月份增加。结论:本研究认为疾病发生频率与气象因素有关,但月相周期与患者就诊频率无统计学关系。
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引用次数: 0
Objective Evaluation of Smell and Taste Senses in COVID-19 Patients. 目的评价新冠肺炎患者的嗅觉和味觉功能。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-09-01 Epub Date: 2022-11-15 DOI: 10.4274/tao.2022.2022-6-1
Altan Kaya, Serkan Altıparmak, Mehmet Yaşar, İbrahim Özcan, İlhami Çelik

Objective: The severe acute respiratory syndrome-coronavirus-2 pandemic is one of the largest of the recent times and can cause many symptoms including smell and taste disorders. In the literature, smell disorders caused by coronavirus disease-2019 (COVID-19) have been reported within a wide range from 3.2% to 98.3%. A small number of these studies demonstrated smell and taste disorders through objective tests. Our aim in this study was to determine the prevalence of smell and taste disorders in hospitalized patients due to COVID-19 infection.

Methods: The study was carried out with 100 patients who were positive for real-time polymerase chain reaction and treated at the Kayseri City Hospital, and 100 healthcare worker relatives. We used the Connecticut Chemosensory Clinical Research Center test to evaluate the sense of smell. Sense of taste was evaluated using four different standardized bottles of preparations, and the results were scored according to the patients' statements.

Results: Patient (Group 1) and control (Group 2) groups were compared for age, gender, smell and taste disorders. There were 39 women and 61 men in the patient group, and 40 women and 60 men in the control group. Mean age was 50.2±1.37 (range 21-70) years in Group 1 and 47.6±1.25 (range 18-70) years in Group 2, and there was no significant difference between the two groups. While the rate of smell disorder was 80% in Group 1, we found this rate as 35% in Group 2. Taste disturbance was identified in 38 patients, of whom 16 had mild hypogeusia, 17 had moderate hypogeusia, four had severe hypogeusia, and one patient had ageusia. We found that taste disorder was 38% in Group 1 and 3% in Group 2.

Conclusion: Smell and taste dysfunctions are very common symptoms in COVID-19 patients. The results obtained using objective test methods are higher than the rates obtained from patient statements.

目的:本次严重急性呼吸综合征-冠状病毒-2大流行是近年来最大的疫情之一,可引起包括嗅觉和味觉障碍在内的多种症状。在文献中,由冠状病毒病-2019 (COVID-19)引起的嗅觉障碍的报告范围从3.2%到98.3%不等。这些研究中有一小部分通过客观测试证明了嗅觉和味觉障碍。本研究的目的是确定因COVID-19感染住院患者嗅觉和味觉障碍的患病率。方法:对100例在开塞利市医院实时聚合酶链反应阳性的患者和100名医护人员家属进行研究。我们使用康涅狄格化学感觉临床研究中心的测试来评估嗅觉。使用四种不同的标准瓶制剂对味觉进行评估,并根据患者的陈述对结果进行评分。结果:比较患者(1组)和对照组(2组)的年龄、性别、嗅觉和味觉障碍。患者组有39名女性和61名男性,对照组有40名女性和60名男性。1组患者平均年龄为50.2±1.37岁(21 ~ 70岁),2组患者平均年龄为47.6±1.25岁(18 ~ 70岁),两组间差异无统计学意义。而嗅觉障碍的比例在第一组为80%,我们发现这一比例在第二组为35%。38例患者出现味觉障碍,其中轻度缺觉16例,中度缺觉17例,重度缺觉4例,老年1例。我们发现味觉障碍在第一组是38%第二组是3%结论:嗅觉和味觉功能障碍是新冠肺炎患者常见的症状。使用客观测试方法获得的结果高于从患者陈述获得的比率。
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引用次数: 3
CARE (CAse REport) Guidelines: A Recipe for More Transparent Case Reports. CARE(病例报告)指南:更透明病例报告的配方。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-06-01 Epub Date: 2022-08-31 DOI: 10.4274/tao.2022.2022-01
Ali Bayram
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引用次数: 0
Posterior Cervical Intramuscular Schwannoma Within the Trapezius Muscle: A Case Report. 颈后斜方肌肌内神经鞘瘤1例报告。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-06-01 Epub Date: 2022-08-31 DOI: 10.4274/tao.2022.2022-1-8
Naoto Koike, Hisashi Hasegawa, Hiroumi Matsuzaki, Takeshi Oshima

Schwannomas are benign soft tissue tumors derived from the Schwann cells of the peripheral nerves. An intramuscular schwannoma arising within the trapezius muscle in the posterior neck is rare. We report a case of a 31-year-old woman with an intramuscular schwannoma in the trapezius muscle. A painless and smooth-surfaced mass from 10 years ago was evident on palpation in the right posterior neck. Ultrasonography revealed an oval mass with clear borders and slight internal blood flow. No continuous hypoechoic lesions were noted at the tip of the mass. Magnetic resonance imaging of the neck revealed a mass in the right posterior cervical trapezius muscle with isointensity on T1-weighted imaging and heterointensity on T2-weighted imaging. Based on these findings, a schwannoma was suspected. Ultrasonography guided fine needle aspiration cytology revealed no significant findings. During surgery, a white-colored, encapsulated-tumor mass was found in the trapezius muscle. Histopathologically, hypocellular and hypercellular areas of fusiform cells were conspicuous, and nuclear palisading was observed in a part of the hypercellular region, confirming the diagnosis of schwannoma. To our knowledge, this is an extremely rare report of an intramuscular schwannoma within the trapezius muscle; herein, we report its clinical, radiological, and pathological features.

神经鞘瘤是源自周围神经的雪旺细胞的良性软组织肿瘤。肌内神经鞘瘤产生于斜方肌在后颈部是罕见的。我们报告一例31岁女性斜方肌肌内神经鞘瘤。右后颈部触诊可见10年前无痛、表面光滑的肿块。超声显示一个椭圆形肿块,边界清晰,内部有少量血流。肿块尖端未见连续低回声病变。颈部磁共振成像显示右侧颈后斜方肌肿块,t1加权成像等强度,t2加权成像异强度。基于这些发现,我们怀疑是神经鞘瘤。超声引导下细针穿刺细胞学检查未见明显变化。手术中,在斜方肌中发现一个白色的包裹性肿瘤块。组织病理学上梭状细胞低细胞区和高细胞区明显,部分高细胞区可见核栅栏,证实神经鞘瘤的诊断。据我们所知,这是一个非常罕见的斜方肌肌内神经鞘瘤的报告;在此,我们报告其临床,放射学和病理特征。
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引用次数: 0
Use of Flexible Bronchoscopy in Foreign Body Aspiration. 柔性支气管镜在异物吸出中的应用。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-06-01 Epub Date: 2022-08-31 DOI: 10.4274/tao.2022.2022-6-6
Gökçen Ünal, Aslı İmran Yılmaz, Tahir Tok, Sevgi Pekcan

Objective: Foreign body aspiration remains a serious health problem with a potential for severe consequences, and acute and chronic problems in children. It therefore demands immediate intervention. Rigid bronchoscopy has long been the method of choice for foreign body removal but is now being replaced by flexible bronchoscopy which offers reduced trauma and the ability to access distal bronchial regions. In the presented study we assessed the patients who underwent flexible bronchoscopy for foreign body removal in our clinic.

Methods: We reviewed the records of 20 patients who underwent flexible bronchoscopy due to suspected foreign body aspiration and had a foreign body removed in our clinic. Patients were analyzed in terms of sociodemographic data, foreign bodies removed, method of foreign body removal, foreign body location and time to diagnosis.

Results: Our study group included nine females and 11 males. The removed foreign body was organic in 19 of the 20 patients and inorganic in one patient. Hard organic food, such as hazelnuts, peanuts, seeds, almonds, and raw corn kernel were identified in 12 patients, a piece of fishbone in one patient and a piece of gelatin in another. The pieces of soft organic food identified were apple in one patient, egg in one patient, and boiled corn kernel in one patient and removed by suction. The foreign body was removed using forceps in nine patients, and a basket was used successfully in seven patients.

Conclusion: Foreign bodies can be removed with minimal complication using flexible bronchoscopy, basket, and forceps in children.

目的:异物吸入仍然是一个严重的健康问题,可能造成严重后果,并对儿童造成急性和慢性问题。因此,需要立即进行干预。长期以来,刚性支气管镜检查一直是异物清除的首选方法,但现在正被柔性支气管镜检查所取代,后者减少了创伤,并能够进入远端支气管区域。在本研究中,我们评估了在我们诊所接受柔性支气管镜手术的患者。方法:我们回顾了20例因疑似异物吸入而行柔性支气管镜检查并取出异物的患者的记录。分析患者的社会人口学资料、异物清除、异物清除方法、异物位置和诊断时间。结果:我们的研究组包括9名女性和11名男性。20例患者中有19例异物为有机物,1例为无机物。在12名患者中发现了硬有机食品,如榛子、花生、种子、杏仁和生玉米粒,在一名患者中发现了一块鱼骨,在另一名患者中发现了一块明胶。其中一名患者食用了苹果,一名患者食用了鸡蛋,一名患者食用了煮熟的玉米粒,并通过抽吸将其取出。9例患者使用镊子取出异物,7例患者成功使用篮子取出异物。结论:儿童使用柔性支气管镜、支气管篮和支气管钳可清除异物,并发症少。
{"title":"Use of Flexible Bronchoscopy in Foreign Body Aspiration.","authors":"Gökçen Ünal,&nbsp;Aslı İmran Yılmaz,&nbsp;Tahir Tok,&nbsp;Sevgi Pekcan","doi":"10.4274/tao.2022.2022-6-6","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-6-6","url":null,"abstract":"<p><strong>Objective: </strong>Foreign body aspiration remains a serious health problem with a potential for severe consequences, and acute and chronic problems in children. It therefore demands immediate intervention. Rigid bronchoscopy has long been the method of choice for foreign body removal but is now being replaced by flexible bronchoscopy which offers reduced trauma and the ability to access distal bronchial regions. In the presented study we assessed the patients who underwent flexible bronchoscopy for foreign body removal in our clinic.</p><p><strong>Methods: </strong>We reviewed the records of 20 patients who underwent flexible bronchoscopy due to suspected foreign body aspiration and had a foreign body removed in our clinic. Patients were analyzed in terms of sociodemographic data, foreign bodies removed, method of foreign body removal, foreign body location and time to diagnosis.</p><p><strong>Results: </strong>Our study group included nine females and 11 males. The removed foreign body was organic in 19 of the 20 patients and inorganic in one patient. Hard organic food, such as hazelnuts, peanuts, seeds, almonds, and raw corn kernel were identified in 12 patients, a piece of fishbone in one patient and a piece of gelatin in another. The pieces of soft organic food identified were apple in one patient, egg in one patient, and boiled corn kernel in one patient and removed by suction. The foreign body was removed using forceps in nine patients, and a basket was used successfully in seven patients.</p><p><strong>Conclusion: </strong>Foreign bodies can be removed with minimal complication using flexible bronchoscopy, basket, and forceps in children.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 2","pages":"88-94"},"PeriodicalIF":0.6,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b5/a4/tao-60-88.PMC9435390.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40355982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Do the Age of Implantation, the Widths of Internal Acoustic Canal and Bony Cochlear Nerve Canal Affect the Auditory Performance of Primary School Children with Bilateral Cochlear Implants? 小学生双侧人工耳蜗植入年龄、内听道和骨耳蜗神经管宽度对听力的影响?
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-06-01 Epub Date: 2022-08-31 DOI: 10.4274/tao.2022.2021-9-5
Ozan Özdemir, Abdullah Soydan Mahmutoğlu, Enes Yiğit, Mustafa Çakır, Özgür Yiğit

Objective: To reveal the correlation between implantation age, the internal acoustic canal (IAC) width, bony cochlear nerve canal (BCNC) width, and auditory performance in primary school children with bilateral cochlear implantation (CI).

Methods: Preoperative IAC and BCNC widths of 57 pre-lingually deaf children aged 7-11 years who had previously undergone bilateral CI in our institution were reviewed and cut-off values were calculated. Twenty-four patients who had additional problems and could not attend school and those who refused to participate in the study were excluded. The remaining 33 were invited to the hospital, and their speech perception tests, and language development scores were analyzed (16 of 33 patients had been operated on before the age of 24 months).

Results: The cut-off values calculated from the 114 ears of 57 patients were 3.86 mm for IAC width and 1.56 mm for BCNC width. The auditory performances of the 33 patients after CI were not significantly different in the narrow and normal width groups. However, speech perception test results, and language development scores of patients implanted before the age of 24 months were significantly higher.

Conclusion: There are some studies showing that children with bilateral sensorineural hearing loss have narrower IAC and BCNC widths. However, we concluded that the widths of the IAC and the bone cochlear nerve canal did not affect auditory performance. We found that implantation age is the single most important determinant of speech-language development after CI.

目的:探讨双侧人工耳蜗植入术(CI)小学生植入术年龄、内耳道(IAC)宽度、骨耳蜗神经管(BCNC)宽度与听力表现的关系。方法:回顾性分析我院57例7 ~ 11岁曾行双侧CI的学龄前语聋儿童术前IAC和BCNC宽度,计算截断值。24名有其他问题且不能上学的患者和拒绝参加研究的患者被排除在外。其余33名被邀请到医院,对他们的语言感知测试和语言发展分数进行分析(33名患者中有16名在24个月前接受过手术)。结果:57例患者114耳计算出的截值为IAC宽度3.86 mm, BCNC宽度1.56 mm。33例患者CI后的听觉表现在窄宽度组和正常宽度组之间无显著差异。然而,在24个月前植入的患者的语音感知测试结果和语言发展评分明显更高。结论:有研究表明双侧感音神经性听力损失患儿IAC和BCNC宽度较窄。然而,我们得出结论,IAC和骨耳蜗神经管的宽度不影响听觉表现。我们发现植入年龄是CI后言语语言发展的最重要的决定因素。
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引用次数: 0
Comparison of Treatment Outcomes Between Total and Near Total Glossectomy with Larynx Preservation and Flap Reconstruction: A Single Institution Experience with 23 Patients. 23例舌全切和近全切喉保留瓣重建治疗效果比较。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-06-01 Epub Date: 2022-08-31 DOI: 10.4274/tao.2022.2022-4-1
Uygar Levent Demir, Mustafa Aslıer, Hakkı Caner İnan

Objective: The purpose of this study was to evaluate the functional and oncological outcomes of total glossectomy with laryngeal preservation (TGLP) compared to near-total glossectomy with laryngeal preservation (nTGLP).

Methods: In this retrospective study, the data of 23 patients who underwent either TGLP or nTGLP between January 2010 and December 2020 in a tertiary university hospital were analyzed. The data including demographic findings, tumor stage, extent of surgery and technique, method of reconstruction, complications, overall survival (OS) and recurrence-free survival (RFS), and tracheostomy and gastric tube dependence during follow-up were assessed.

Results: Of the 23 eligible patients, 15 had undergone nTGLP (Group 1) and 8 had undergone TGLP (Group 2). Tracheostomy dependence and gastric tube dependence rates at the sixth month were 3/19 (15.7%) and 12/19 (63.1%), respectively, with no significant differences between the two groups. OS and RFS at one year were 47.6% and 27.8%, respectively, for the study population. OS rate showed significance with nodal positivity and extranodal extension (p=0.004 for both) only, but not within patient groups (p=0.734).

Conclusion: Both TGLP and nTGLP are feasible treatment options in patients with advanced tongue cancer with no differences in terms of functional and oncological results. Survival rates are still not satisfactory, and recurrences are high despite appropriate treatments. Proper selection of patients who are highly motivated and willing for long-term postoperative rehabilitation is essential.

目的:本研究的目的是评估全舌切除术合并喉保留(TGLP)与近全舌切除术合并喉保留(nTGLP)的功能和肿瘤预后。方法:回顾性分析2010年1月至2020年12月在某三级大学医院接受TGLP或nTGLP治疗的23例患者的资料。评估随访期间的人口学资料、肿瘤分期、手术范围和技术、重建方法、并发症、总生存期(OS)和无复发生存期(RFS)、气管造口术和胃管依赖性。结果:23例符合条件的患者中,接受nTGLP治疗的患者15例(1组),接受TGLP治疗的患者8例(2组)。6个月气管造口依赖率和胃管依赖率分别为3/19(15.7%)和12/19(63.1%),两组间差异无统计学意义。研究人群一年的OS和RFS分别为47.6%和27.8%。OS率仅与淋巴结阳性和结外延伸相关(p=0.004),而在患者组内无统计学意义(p=0.734)。结论:TGLP与nTGLP均为晚期舌癌患者可行的治疗方案,在功能和肿瘤结果上无差异。生存率仍然不令人满意,尽管有适当的治疗,复发率仍然很高。正确选择积极性高且愿意长期术后康复的患者是至关重要的。
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引用次数: 1
Olfactory Neuroepithelium in Olfactory Cleft Polyps: Do They Have Any Effect on Olfaction Results After Endoscopic Sinus Surgery? 嗅裂息肉的嗅神经上皮:它们对鼻内镜手术后的嗅觉结果有影响吗?
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-06-01 Epub Date: 2022-08-31 DOI: 10.4274/tao.2022.2022-4-5
Cengiz Özcan, Onur İsmi, Feyzi Meşe, İclal Gürses, Yusuf Vayisoğlu, Kemal Görür

Objective: How the presence of olfactory structures in olfactory cleft polyps (OCPs) affect olfaction function outcomes after surgical removal has not yet been investigated. In this study we aimed to assess the presence of olfactory structures in OCPs and correlate these findings with olfactory outcomes after endoscopic sinus surgery (ESS).

Methods: Twenty seven patients with OCP underwent preoperative topical and systemic steroid treatment and ESS. Biopsies from the middle meatal polyps (MMPs) and OCPs were immunohistochemically analyzed for olfactory marker protein (OMP). The smell diskettes olfaction test was applied to patients at baseline, after steroid treatment (AST) and after ESS.

Results: OCPs exhibited OMP staining more commonly and intensely compared to MMPs (p=0.008), however, there were no correlations between OMP staining scores and any of the olfaction scores (p>0.05). Steroid treatment increased smell function significantly (p<0.001), however, there were no significant differences between AST and after ESS smell scores (p=0.17). There were significant correlations between smell gains AST and final smell gains after ESS (r=0.665, p<0.001).

Conclusion: OCPs contain olfactory neuroepithelium more commonly and intensely than MMPs in nasal polyp patients. However, surgical importance of this finding is controversial because removal of these polyps did not decrease smell function postoperatively in our study. Nasal polyp patients who will take steroid treatment pre-operatively must be informed that the success of ESS on olfaction depends on the response of the steroid treatment and ESS AST might not have additional favorable effect on smell function.

目的:嗅觉结构的存在对嗅觉裂息肉(OCPs)手术切除后嗅觉功能的影响尚不清楚。在这项研究中,我们旨在评估嗅觉结构在ocp中的存在,并将这些发现与内窥镜鼻窦手术(ESS)后的嗅觉结果联系起来。方法:27例OCP患者术前接受局部和全身类固醇治疗和ESS治疗。对中金属息肉(MMPs)和OCPs的活检组织进行嗅觉标记蛋白(OMP)的免疫组织化学分析。嗅觉测试应用于基线、类固醇治疗(AST)后和ESS后的患者。结果:与MMPs相比,OCPs表现出更普遍和强烈的OMP染色(p=0.008),但OMP染色评分与任何嗅觉评分之间均无相关性(p>0.05)。结论:在鼻息肉患者中,OCPs比MMPs含有更多的嗅神经上皮。然而,这一发现的外科重要性是有争议的,因为在我们的研究中,切除这些息肉并没有降低术后的嗅觉功能。术前接受类固醇治疗的鼻息肉患者必须被告知,ESS对嗅觉的成功取决于类固醇治疗的反应,ESS AST可能不会对嗅觉功能产生额外的有利影响。
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引用次数: 2
CARE (CAse REport) Guidelines: A Recipe for More Transparent Case Reports CARE(病例报告)指南:更透明病例报告的配方
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-06-01 DOI: 10.4274/tao.2022.202201
Ali Bayram
Case reports are the types of medical writing that are often described as the scientific documentation of a single clinical observation (1). The first examples of case reports probably date back to the BC era (2). Since then, case reports found themselves a permanent position in the medical literature for the purposes of informing about the findings of new diseases and modes of medical interventions, describing the adverse or beneficial outcomes of a procedure, and have also been used for teaching purposes (3). There are seminal examples of case reports in the medical literature that have antecedently addressed the beneficial or adverse effects of treatment protocols in specific clinical entities such as the relationship between phocomelia and thalidomide, or propranolol treatment for infantile hemangioma (4, 5). Despite, however, the numerous contributions of case reports to the medical literature, controversies have emerged among the scientific community regarding their varying quality and level of evidence, especially in the last 20 years (6).
病例报告是医学写作的类型,通常被描述为单一临床观察的科学文档(1)。病例报告的第一个例子可能可以追溯到公元前时代(2)。从那时起,病例报告在医学文献中占据了永久地位,目的是了解新疾病的发现和医疗干预模式,描述手术的不良或有益结果,也被用于教学目的(3)。医学文献中有一些开创性的病例报告,这些病例报告预先讨论了治疗方案在特定临床实体中的有益或不良影响,如phocomelia和沙利度胺之间的关系,或普萘洛尔治疗婴儿血管瘤(4,5)。然而,尽管病例报告对医学文献做出了大量贡献,但科学界对其不同的证据质量和水平仍存在争议,尤其是在过去20年中(6)。
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引用次数: 0
期刊
Turkish Archives of Otorhinolaryngology
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