Archivos de Medicina最新文献

{"title":"Vacunaciandoacute;n en Pacientes con Enfermedad Renal Crandoacute;nica","authors":"Jorge-Eduardo Rico-Fontalvo, Rodrigo Daza-Arnedo, Víctor Leal-Martínez, Nehomar Pájaro-Galvis, Emilio Abuabara-Franco, Christian Pérez-Calvo, Carlos Jaramillo-Pérez, Isabella Uparella-Gulfo, M. Paternina","doi":"10.36648/1698-9465.17.1.1461","DOIUrl":"https://doi.org/10.36648/1698-9465.17.1.1461","url":null,"abstract":"Infectious complications in patients with chronic kidney disease are described as the second main cause of hospitalization and generate an impact on mortality, which is why vaccination becomes one of the pillars to prevent infections in patients with kidney disease. Patients diagnosed with chronic kidney disease present immunological dysfunction, which makes them prone to complications of an infectious type, mediated by viruses, bacteria, parasites and other microorganisms. This is why the benefits obtained by applying a correct immunization scheme in this type of patient are enormous, frankly impacting on the possible complications that they may have. Methodology: An advanced search was carried out with the terms DeSC and MeSH: Chronic kidney disease; Vaccination; Hepatitis B; Hepatitis A; Pneumococcus; Influenza; Herpes zoster. The Clinical Key, Embase, PubMed and Ovid search engines were used, obtaining a total of 146 results, including original articles, case reports, and literature reviews; Through narrative analysis, and based on selection criteria such as epidemiological data from the last 5 years on chronic kidney disease and infections, in addition to clinical practice guidelines on the different vaccination schemes, a total of 45 articles were selected that were used to the preparation of this literature review.","PeriodicalId":44458,"journal":{"name":"Archivos de Medicina","volume":"17 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69690276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sandiacute;ndrome de McKittrick-Wheelock Como Causa de Hipokalemia Refractaria y Lesiandoacute;n Renal Aguda. Reporte de Caso","authors":"Antonio Peña-Guevara, Fern, O. Araque-Villaquiran, Adrian-Felipe Romero-Ocampo, Lucia Millán-Tróches, Christian Pérez-Calvo, Nehomar Pájaro-Galvis, Daniella-Valentina Arrieta-Segura, Camilo-Andrés Martínez-García, Marleidy-Yised Carreño Rincón, Carlos Jaramillo-Pérez","doi":"10.36648/1698-9465.21.17.1475","DOIUrl":"https://doi.org/10.36648/1698-9465.21.17.1475","url":null,"abstract":"El Sindrome de McKittrick-Wheelock es una entidad infrecuente caracterizada por diarrea de tipo secretora con alteraciones hidroelectroliticas asociado a la presencia de lesiones tumorales en colon, especialmente de tipo adenoma velloso en recto. Se presenta con estados de deshidratacion severa y trastornos hidroelectroliticos prinicipalmente hipokalemia e hiponatremia concomitantemente con acidosis metabolica. El principal mecanismo implicado es la sopreproduccion de prostaglandina E2 por las celulas tumorales. La perdida de volumen intravascular puede conllevar a complicaciones como shock hipovolemico y lesion renal aguda. Reportamos el caso de un paciente masculino con cuadro clinico de 15 dias de evolucion de diarrea, alteraciones hidroelectroliticas refractarias y requerimiento de terapia de reemplazo renal con presencia de adenoma velloso en recto y sigmoide.","PeriodicalId":44458,"journal":{"name":"Archivos de Medicina","volume":"17 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69691223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estenosis Critica de la Arteria Carotida Interna: Evento Raro en un Adulto Joven: Reporte de Caso","authors":"Oscar Vergara-Serpa, Oriana Arrollo-Ripoll, Alonso Cortina-Gutiérrez, Nehomar Eduardo Pájaro Galvis, Mario Montoya-Jaramillo, Heriberto Cabrales-Dajil, Carlos Reyes-Jaraba, Jorge-Eduardo Rico-Fontalvo, Rodrigo Daza-Arnedo, Christian Pérez-Calvo","doi":"10.36648/1698-9465.21.17.1456","DOIUrl":"https://doi.org/10.36648/1698-9465.21.17.1456","url":null,"abstract":"Introduccion: la estenosis critica de la arteria carotida interna (ACI) es poco frecuente en adultos menores de 45 anos. Esta asociada multiples factores de riesgo, y dentro de ellos con menor frecuencia, se han documentado los trastornos del colageno como la vasculitis, existiendo ademas una amplia variacion en la gravedad de la presentacion clinica. Caso Clinico: paciente de 23 anos que ingreso al servicio de urgencias, con cefalea fontoparietal derecha mas signos de bandera roja y hemiparesia izquierda de predominio braquial; que desarrollo lesiones isquemicas a nivel subcortical y paraventricular, comprometiendo el lobulo parietal derecho secundario a estenosis critica de la (ACI) derecha en su segmento supraclinoideo que no se sometio a ningun tipo de procedimiento de revascularizacion quirurgica o endovascular. Conclusiones: se presento un caso de estenosis de la ACI, con alta sospecha que la causa de estenosis en nuestra paciente joven sin factores de riesgo sea el debut de una colagenopatia, a pesar de que los marcadores inmunologicos en el momento esten negativos. Se destaca un factor de riesgo importante, madre con Lupus eritematoso sistemico. Se indico tratamiento con terapia antiplaquetaria y estatinas; no se inicio terapia inmunosupresora, ni se realizo angioplastia con balon sin stent indicado de manera inicial, por el riesgo de ruptura de vaso; pero si el manejo medico inicial falla y la paciente persiste con isquemias cerebrales documentadas con estudios de imagenes seriadas de manera periodica, se contemplara la posibilidad de tratamiento invasivo basado en el riesgo/beneficio.","PeriodicalId":44458,"journal":{"name":"Archivos de Medicina","volume":"17 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69690621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agonistas Del Receptor Glp-1: Desde su Efecto Fisiologico en el Sistema Incretina Hasta du Rol en Enfermedad Renal Diabetica","authors":"Jorge-Eduardo Rico-Fontalvo, Rodrigo Daza-Arnedo, Maria Raad-Sarabia, Nehomar Pájaro-Galvis, José Correa-Guerrero, Alba Villacob-Oviedo, Andrea Florez-Meneces, Christian Pérez Calvo, Laura HerreraSetuain, Andrés YoliGarrido, Yamile Sepulveda-Hern, ez, Víctor Leal-Martínez, John Mauricio Lopera-Vargas, E. Franco","doi":"10.36648/1698-9465.21.17.1463","DOIUrl":"https://doi.org/10.36648/1698-9465.21.17.1463","url":null,"abstract":"espanolLa Diabetes Mellitus es una enfermedad muy prevalente y con alto riesgo de complicaciones micro y macrovasculares. Hasta el 20-40% de los pacientes diabeticos desarrollan enfermedad renal diabetica en algun momento de su evolucion. Recientemente, el tratamiento hipoglucemiante no solo se orienta al control glucemico, sino tambien a impactar en desenlaces cardiovasculares y renales. Dentro de estas moleculas, encontramos los analogos GLP-1, considerados un pilar en el tratamiento hipoglucemiante para los pacientes diabeticos con enfermedad cardiovascular. Objetivo: Describir los principales aspectos clinicos de los agonistas GLP-1, su mecanismo de accion y su rol fisiologico en los desenlaces cardiovasculares y renales de la diabetes mellitus. Metodologia: Se realizo una busqueda avanzada con los terminos DeCS: “Nefropatia Diabetica; Agonistas del receptor GLP-1, Peptidos Similares al Glucagon; Diabetes Mellitus” utilizando los motores de busqueda Clinical Key, Embase, PubMed y Ovid, obteniendo un total de 413 resultados, entre articulos originales, reportes de casos, series de casos y revisiones de la literatura, se seleccionaron un total de 70 articulos utilizados para la elaboracion de la revision de la literatura. Conclusion: Las terapias basadas en analogos GLP-1 en la diabetes mellitus, es un pilar terapeutico en individuos con factores de riesgo para enfermedad renal diabetica, debido a sus beneficios demostrados en la disminucion de los desenlaces renales compuestos. EnglishDiabetes Mellitus is a very prevalent disease with a high risk of micro and macrovascular complications. Up to 20 - 40% of diabetic patients develop diabetic kidney disease at some point in their evolution. Recently, hypoglycemic treatment is not only aimed at glycemic control, but also at impacting cardiovascular and kidney outcomes. Among these molecules, we find the GLP-1 analogs (Type 1 glucagon-like peptide), considered a mainstay in hypoglycemic treatment for diabetic patients with cardiovascular disease. Objective: To describe the main clinical aspects of GLP-1 agonists, their mechanism of action and their physiological role in the cardiovascular and renal outcomes of diabetes mellitus. Methodology: An advanced search was carried out with the DeCS terms: “Diabetic Nephropathy; GLP-1 Receptor Agonists, Glucagon-Like Peptides; Diabetes Mellitus” using the Clinical Key, Embase, PubMed and Ovid search engines, obtaining a total of 413 results, among original articles, case reports, case series and literature reviews, a total of 72 articles were selected used for the preparation of the literature review. Conclusion: Therapies based on GLP-1 analogues in diabetes mellitus are a therapeutic mainstay in individuals with risk factors for diabetic kidney disease, due to its proven benefits in reducing composite kidney outcomes.","PeriodicalId":44458,"journal":{"name":"Archivos de Medicina","volume":"17 1","pages":"2"},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69690785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infecciandoacute;n por Sars-Cov-2 y Sindrome de Guillain-Barrandeacute;","authors":"Juan-Manuel Montaño-Lozada, E. Castillo-Támara, María-Alej, ra Mendoza-Ospina, Gonzalo Zúñiga-Escobar, Christian Pérez-Calvo, Daniella-Valentina Arrieta-Segura, Carlos Jaramillo-Pérez","doi":"10.36648/1698-9465.21.17.1476","DOIUrl":"https://doi.org/10.36648/1698-9465.21.17.1476","url":null,"abstract":"El sindrome de Guillain-Barre es la causa mas frecuente de paralisis flacida a nivel mundial, genera una gran carga neuroinmune y provoca clasicamente polineuropatia aguda desmielinizante de etiologia multiple. Varios agentes infecciosos han sido relacionados como desencadenantes de su fisiopatologia tales como Campylobacter jejuni, haemophylus influenzae, virus del Zika, entre otros; Ademas, los factores de riesgo ambientales y geneticos podrian influir generando un mayor impacto en la enfermedad. El surgimiento y propagacion a nivel mundial del virus emergente de la familia SARS tomo por sorpresa a la comunidad cientifica, constituyendo un reto para la humanidad. Los coronavirus son importantes patogenos humanos y animales. Se ha relacionado al virus SARS COV-2 con complicaciones neurologicas de manera frecuente en los pacientes hospitalizados, cuando la carga de inmuno-compromiso supone ser mayor, dejando entrever la posible relacion entre este agente infeccioso y el sindrome de Guillain-Barre, encontrando algunos reportes y series de casos con tasas que varian segun la metodologia del estudio y las caracteristicas de los pacientes. El sindrome de Guillain-barre establece una emergencia neurologica y un gran reto diagnostico de una enfermedad potencialmente mortal.","PeriodicalId":44458,"journal":{"name":"Archivos de Medicina","volume":"17 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69691348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Terapia Fandiacute;sica Temprana para la Prevenciandoacute;n del Delirio en la Unidad de Cuidados Intensivos","authors":"Christian Camilo Cardona Ocampo, Jessica María Londoño Agudelo, Diana Silva","doi":"10.36648/1698-9465.21.17.1477","DOIUrl":"https://doi.org/10.36648/1698-9465.21.17.1477","url":null,"abstract":"El delirio es una condicion tan comun como riesgosa en pacientes hospitalizados, especialmente en aquellos adultos mayores que requieren internacion en la unidad de cuidados intensivos, siendo un marcador independiente de mal pronostico para ellos (Incluyendo muerte hospitalaria, tiempo prolongado de hospitalizacion, aumento de costos relacionados a la atencion y deterioro cognitivo a largo plazo). En la unidad de cuidados intensivos se presenta como una forma aguda de disfuncion organica, caracterizada por alteracion de la conciencia y la cognicion que se desarrolla rapidamente y que fluctua a lo largo del dia. Se ha descrito que estrategias no farmacologicas tienen el mayor potencial a la hora de prevenir la aparicion de dicha condicion, dentro de estas, vale la pena destacar la terapia fisica temprana pues ademas de impactar positivamente en la prevencion del delirio, mejora la funcionalidad y previene el sindrome de desacondicionamiento del paciente critico. En esta revision discutiremos el diagnostico y herramientas clinicas utiles para el mismo, factores de riesgo y el papel de la rehabilitacion fisica en la prevencion del delirio.","PeriodicalId":44458,"journal":{"name":"Archivos de Medicina","volume":"10 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69691808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor Miofibroblástico Inflamatorio del Hígado: Reporte de un Caso Inflammatory Myofibroblastic Tumor of the Liver: A Case Report","authors":"Javier Antonio Reyes-Quan, Elmys Vannesa Altamirano, Juan Francisco Ayestas, Laparoscópica Avanzada","doi":"10.36648/1698-9465.21.S2.105","DOIUrl":"https://doi.org/10.36648/1698-9465.21.S2.105","url":null,"abstract":"Background: Myofibroblastic inflammatory tumors are a group of mesenquimatous tumors that have predilection for children and young adults. It´s diagnose represents a challenge due to the unspecific symptoms and image studies findings. The definitive diagnose is given by characteristic histopathological findings. The complete tumor resection is the accepted treatment. Case Presentation: A 21 year old woman with previous history of one year of abdominal pain, localized on the epigastrium, accompanied with fever, asthenia, adynamia and weight loss. Laboratory exams showed microcytic anemia and thrombocytosis. The computerized tomography showed a cystic heterogeneous tumor on the left hepatic lobe. Patient underwent a laparotomy finding a cystic tumor on hepatic segments II and III, surgical resection was made with any complications. The histopathological study reported a myofibroblastic inflammatory tumor. Conclusiones: Myofibroblastic inflammatory tumors are entities difficult to diagnose. A radical resection should be considered for its treatment with patient follow up due to its potential recurrence.","PeriodicalId":44458,"journal":{"name":"Archivos de Medicina","volume":"17 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69691993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of COVID-19 on Pharmaceutical Industry: Status of Clinical Trials and Mitigation Strategies","authors":"A. B. Sawad, F. Turkistani","doi":"10.36648/1698-9465.21.17.1486","DOIUrl":"https://doi.org/10.36648/1698-9465.21.17.1486","url":null,"abstract":"Background: COVID-19 could affect clinical trials because avoidance of close contact between people constitutes one of the approaches that have been recommended to ensure that individuals do not become exposed to the coronavirus. Objectives: To discuss the impact of COVID-19 on clinical trials within the pharmaceutical industry. In addition, the paper examines some strategies that can be adopted to cope with impact of COVID-19 on clinical trials and thus ability to continue conducting the trials. Methods: This is a narrative review article. We provided a synthesis of current literature and guidelines obtained from searches on many electronic databases (PubMed/Medline, EMBASE, and Cochrane Library), Google search engine, the United States (US) Food and Drug Administration (FDA) website, and hand searches on the bibliography of the articles. Results: There is a significant impact of COVID-19 on clinical trials. The impact includes: undermining sponsors’ economic ability to fund clinical trials, social distancing, impeding recruitment of participants for non-COVID-19 clinical trials, discouraging participants from visiting clinical sites due to fear of COVID-19 infections, and making trial staff to opt for remote working. The US FDA published new guidelines to be applied during the ongoing pandemic. Mitigation strategies to ensure continuity of clinical trials include: adopting participant enabling measures, modifying clinical trial protocol, providing logistical and supply chain management support, embracing remote data review and clinical site monitoring, and offering extra site support services. Conclusions: COVID-19 pandemic is disrupting the initiation and continuing ongoing clinical trials. Guidelines have to be followed and strategies for mitigating adverse impacts of COVID-19 need to be applied. Modifying monitoring methods should be done to accommodate the constraints posed by the ongoing COVID-19 pandemic.","PeriodicalId":44458,"journal":{"name":"Archivos de Medicina","volume":"17 1","pages":"5"},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69692294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sandiacute;ndrome Metabandoacute;lico en Adultos: Revisiandoacute;n Narrativa de la Literatura","authors":"María Peinado Martínez, Isaac Dager Vergara, Karol Quintero Molano, Mariana Mogollón Pérez, Andrés Puello Ospina","doi":"10.36648/1698-9465.21.17.1465","DOIUrl":"https://doi.org/10.36648/1698-9465.21.17.1465","url":null,"abstract":"Objetivo: Describir el sindrome metabolico en adultos, caracteristicas clinico epidemiologicas, sus alternativas diagnosticas y preventivas disponibles en la actualidad, por medio de una revision narrativa de la literatura. Materiales y metodos: Se realizo una revision narrativa a traves de una busqueda avanzada con 31 articulos de alto prestigio cientifico entre el periodo del 2010 - 2020, seleccionando aquellos articulos que contenian informacion sobre el sindrome metabolico en adultos. Resultados: Se logro describir al detalle las caracteristicas clinico epidemiologicas, las alternativas diagnosticas y los mecanismos de prevencion para sindrome metabolico en adultos en base a la evidencia actual. Conclusion: Se concluyo que el sindrome metabolico es un estado fisiopatologico complejo que se origina principalmente por un desequilibrio en la ingesta de calorias y el gasto energetico, pero tambien se ve afectado por la composicion genetica/epigenetica del individuo, el predominio del estilo de vida sedentario sobre la actividad fisica y otros factores como la microbiota intestinal y la calidad y composicion de los alimentos, por lo cual se debe educar a la poblacion sobre el peligro para la salud del sindrome metabolico.","PeriodicalId":44458,"journal":{"name":"Archivos de Medicina","volume":"17 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69690589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tromboembolismo Pulmonar y Crisis Hemolandiacute;tica. andiquest;Asociaciandoacute;n Poco Frecuente? Reporte de Caso","authors":"Oscar Vergara-Serpa, Daniel Rodriguez-Peralta, Oriana Arroyo-Ripoll, Nehomar Pájaro-Galvis, Nikolle Cedano-Vélez, Thalia Herrera-Calvo, M. Martinez-Viloria, Alba Villacob-Oviedo, Andrea Florez-Meneces, José Correa-Guerrero, Jorge-Eduardo Rico-Fontalvo","doi":"10.36648/1698-9465.21.17.1469","DOIUrl":"https://doi.org/10.36648/1698-9465.21.17.1469","url":null,"abstract":"La anemia hemolitica autoinmune, es un trastorno caracterizado por produccion de autoanticuerpos dirigidos contra los antigenos de los eritrocitos que deriva en destruccion de los mismos y que supone un espectro heterogeneo de presentacion clinica. Desde el ano 1960 se ha descrito su asociacion a eventos tromboticos por aumento en la liberacion de fibrina y trombina. Se presenta el caso de una paciente femenina de 66 anos a quien, en paralelo a episodio de anemia hemolitica autoinmune, con clinica de disnea y dolor toracico se documenta en tomografia de torax contrastada defectos hipodensos irregulares multiples en la arteria pulmonar derecha y sus ramas lobares en relacion a trombos; hallazgos compatibles con tromboembolismo pulmonar. Aun no se conoce una fisiopatologia clara. No obstante, se han relacionado los eventos hemoliticos a estado de hipercoagulabilidad coexistente. Resulta perentorio para el clinico tener presente el sustrato procoagulante que implica el diagnostico de anemia hemolitica autoinmune para considerar la terapia anticoagulante y sospechar diagnosticos potencialmente mortales.","PeriodicalId":44458,"journal":{"name":"Archivos de Medicina","volume":"17 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69690538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}