Computer-assisted Parkinson's disease-specific gait pattern recognition has gained more attention in the past decade due to its extensive application. In this research study, vision-based gait feature extraction is obtained from the observed skeleton points to support the real-time Parkinson disease prediction and diagnosis in the smart healthcare environment. So, a novel kernel-based principal component analysis (KPCA) is introduced for establishing respective feature extraction and dimensionality reduction on the patient's video data. In this research study, a vision-based Parkinson disease identification system (VPDIS) is developed with a feature-weighted minimum distance classifier model to support the clinical assessment of Parkinson's disease. At the time of experimentation, a steady-state walking style of the patient was captured using the cameras fixed in the smart healthcare environment. Then, the accumulated walking frames from the remote patients were transformed into the required binary silhouettes for the sake of noise minimisation and compression purpose. The resulting experimentation shows that the proposed feature extraction approach has significant improvements on the recognition of target gait patterns from the video-based gait analysis of Parkinson's and normal patients. Accordingly, the proposed VPDIS using feature-weighted minimum distance classifier model provides better prediction time and classification accuracy against the existing healthcare systems that is developed using support vector machine and ensemble learning classifier models.
In many households, preparation of food in normal times proves to be problematic, particularly when parents endeavour to keep their children on a balanced diet. The COVID-19 pandemic has further exacerbated this problem imposing the requirement of social distancing, which led to disruptions in the food supply chain and multiplication of responsibilities faced by families with children. The present study revisits the standard "Diet Problem" to address these challenges and to develop a participatory approach to provide a diversified weekly meal plan that is easy and fun but simultaneously complies with the unique requirements of each participant. This is done by providing a novel framework, which combines linear optimisation with the Parsimonious Analytic Hierarchy Process, a method for individual choices. This novel approach to participatory modelling is tested within two young family settings in Brazil. The model produced through this contemporary framework provides a weekly menu that best meets expectations of the members of a young family in the context of the COVID-19 pandemic.
The increasing prevalence of the chronic disease is of considerable concern to health-care organisations. Prevention programmes to patients with early chronic disease have the potential to improve individual health and quality of life through disease avoidance or delay and to save the medical cost of the health care system. Due to the limited budget in healthcare this study seeks to analyse the feasibility of a programme prior to implementation. A mathematical model is developed to determine incidence reduction rate at which the underlying cost break-even can be achieved; consequently, the programme would be feasible. We show the existence and uniqueness of the underlying incidence reduction and establish the feasibility frontier concerning the trade-offs between intervention effective period and incidence reduction rate. We use a diabetes prevention programme to demonstrate the efficiency and advantage of the model. The proposed model would inform decision-makers scientific principles in determining an intervention for implementation.
Despite massive progress in vaccine coverage globally, the region of sub-Saharan Africa is lagging behind for Sustainable Development Goal 3 by 2030. Sub-national under-immunisation is part of the problem. In order to reverse the current immunisation system's (IMS) underperformance, a conceptual model is proposed that captures the complexity of IMSs in low- and middle-income countries (LMICs) and offers directions for sustainable redesign. The IMS model was constructed based on literature and stakeholder interaction in Rwanda and Kenya. The model assembles the paradigms of planned and emergency immunisation in one system and emphasises the synchronised flows of vaccinee, vaccinator and vaccine. Six feedback loops capture the main mechanisms governing the system. Sustainability and resilience are assessed based on loop dominance and dependency on exogenous factors. The diagram invites stakeholders to share their mental models and. The framework provides a systems approach for problem structuring and policy design.
Without timely assessments of the number of COVID-19 cases requiring hospitalisation, healthcare providers will struggle to ensure an appropriate number of beds are made available. Too few could cause excess deaths while too many could result in additional waits for elective treatment. As well as supporting capacity considerations, reliably projecting future "waves" is important to inform the nature, timing and magnitude of any localised restrictions to reduce transmission. In making the case for locally owned and locally configurable models, this paper details the approach taken by one major healthcare system in founding a multi-disciplinary "Scenario Review Working Group", comprising commissioners, public health officials and academic epidemiologists. The role of this group, which met weekly during the pandemic, was to define and maintain an evolving library of plausible scenarios to underpin projections obtained through an SEIR-based compartmental model. Outputs have informed decision-making at the system's major incident Bronze, Silver and Gold Commands. This paper presents illustrated examples of use and offers practical considerations for other healthcare systems that may benefit from such a framework.
The paper proposes a hybrid metaheuristic algorithm known as harmony search and simulated annealing (HS-SA) for accurate and precise breast malignancy disclosure by integrating harmony search (HS) and simulated annealing (SA) optimisation methods. An enhanced wavelet-based contourlet transform (WBCT) procedure for mining the highlights of the region of interest (ROI) is explored, that allows execution upgradation over other standard procedures. The anticipated HS-SA algorithm aims to reduce the feature dimensions and assemble at the unparalleled optimal feature subset. The SVM classifier fed with the picke.d feature subsets and assisted by varied kernel functions upheld its classification capacities in contrast with the conformist machine learning classification and optimisation methods. The portrayed computer-aided diagnosis (CAD) model is confronted by evaluating its learning capability on two different breast mammographic datasets i) benchmark BCDR-F03 dataset and ii) local mammographic dataset. Preliminary propagations, experimental outcomes, and quantifiable assessments likewise demonstrate that the proposed model is pragmatic and favourable for the automated breast malignancy findings with optimal performance and fewer overheads. The discoveries show that the proposed CAD system (HS-SA+Kernel SVM) is superior to various characterisation accuracy techniques with an accuracy of 99.89% for the local mammographic dataset and 99.76% for benchmark BCDR-F03 dataset, AUC of 99.41% for the local mammographic dataset and 99.21% for reference BCDR-F03 dataset while keeping the element space restricted to only seven feature subsets and computational prerequisites as low as is judicious.
Falls are one of the most common cause of nonfatal and fatal injuries in the U.S. costing over an estimated $54 billion annually. A significant percentage of patients presenting to hospital emergency departments (ED) for falls are hospitalised. This paper analyzes a regional hospital data pertaining to adults presenting to the ED because of falls. We use patient demographics and medical conditions to help identify patients at risk for immediate undesirable outcomes after a fall. Furthermore, we determine the relative risk of patient hospitalisation and surgery and their characteristics. Our results indicate that older patient's, patients arriving by ambulance, patients with higher severity levels and patients with pre-existing comorbidities were at a higher relative risk of hospitalisation and surgery. Furthermore, patients with medical conditions pertaining to femur and tibia fractures, pelvis, renal failure, ambulatory dysfunction, and cellulitis, among others, and non-Hispanic whites were at a much higher relative risk of hospitalisation and surgery.

