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Covid-19 transmission modelling of students returning home from university. 针对大学毕业返乡学生的 Covid-19 传播模型。
IF 1.8 Q4 HEALTH POLICY & SERVICES Pub Date : 2021-01-17 eCollection Date: 2021-01-01 DOI: 10.1080/20476965.2020.1857214
Paul R Harper, Joshua W Moore, Thomas E Woolley

We provide an open-source model to estimate the number of secondary Covid-19 infections caused by potentially infectious students returning from university to private homes with other occupants. Using a Monte-Carlo method and data derived from UK sources, we predict that an infectious student would, on average, infect 0.94 other household members. Or, as a rule of thumb, each infected student would generate (just less than) one secondary within-household infection. The total number of secondary cases for all returning students is dependent on the virus prevalence within each student population at the time of their departure from campus back home. Although the proposed estimation method is general and robust, the results are sensitive to the input data. We provide Matlab code and a helpful online app (http://bit.ly/Secondary_infections_app) that can be used to estimate numbers of secondary infections based on local parameter values. This can be used worldwide to support policy making.

我们提供了一个开源模型,用于估算可能具有传染性的学生从大学回到有其他住户的私人住宅后造成的 Covid-19 二次感染数量。利用蒙特卡洛方法和英国的数据来源,我们预测一名受感染的学生平均会感染 0.94 名其他家庭成员。或者说,根据经验,每个受感染的学生都会产生(略少于)一个家庭内二次感染病例。所有返校学生的二次感染病例总数取决于他们离开校园回家时每个学生群体中的病毒流行率。尽管所提出的估算方法具有通用性和稳健性,但其结果对输入数据非常敏感。我们提供了 Matlab 代码和一个有用的在线应用程序 (http://bit.ly/Secondary_infections_app),可用于根据本地参数值估算二次感染人数。该方法可在全球范围内用于支持政策制定。
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引用次数: 0
Socioeconomic differentials in the burden of paying for healthcare in India: a disaggregated analysis. 印度医疗保健负担的社会经济差异:分类分析。
IF 1.8 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-12-15 eCollection Date: 2022-01-01 DOI: 10.1080/20476965.2020.1848356
Ramna Thakur, Shivendra Sangar

By using nationally representative consumption expenditure surveys (CES) conducted by the National Sample Survey Organisation (NSSO) in 1999-2000, 2004-05 and 2011-12, this paper has analysed the socioeconomic differentials in the burden of paying for healthcare in India. The study found that in all waves of data, the concentration of population reporting OOP health expenditure has shown a shift towards poor population, while the concentration of overshoot expenditure is still constant among the rich which is more pronounced in the rural areas of the country. Furthermore, Muslims and Sikhs among different religions, Scheduled Casts among social categories, self-employed and casual/agricultural labour among household types and rural areas among sectors are more likely to incur OOP health expenditure as compared to their counterparts. This study argues for the universal health insurance coverage to protect households from the significant burden of expenditure on critical healthcare.

通过使用全国抽样调查组织(NSSO)在1999-2000年,2004-05年和2011-12年进行的具有全国代表性的消费支出调查(CES),本文分析了印度支付医疗保健负担的社会经济差异。该研究发现,在所有数据中,报告OOP保健支出的人口集中已向贫困人口转移,而过度支出仍然集中在富人中,这在该国农村地区更为明显。此外,与同类相比,不同宗教中的穆斯林和锡克教徒、社会类别中的排期种姓、家庭类型中的自营职业者和临时/农业劳动力以及各部门中的农村地区更有可能产生OOP保健支出。本研究认为,全民健康保险覆盖范围,以保护家庭从重要的医疗保健支出的重大负担。
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引用次数: 1
"What's the evidence?"-Towards more empirical evaluations of the impact of OR interventions in healthcare. "证据是什么?"--对手术室干预措施对医疗保健的影响进行更多的实证评估。
IF 1.2 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-12-15 eCollection Date: 2022-01-01 DOI: 10.1080/20476965.2020.1857663
Guillaume Lamé, Sonya Crowe, Matthew Barclay

Despite an increasing number of papers reporting applications of operational research (OR) to problems in healthcare, there remains little empirical evidence of OR improving healthcare delivery in practice. Without such evidence it is harder both to justify the usefulness of OR to a healthcare audience and to learn and continuously improve our approaches. To progress, we need to build the evidence-base on whether and how OR improves healthcare delivery through careful empirical evaluation. This position paper reviews evaluation standards in healthcare improvement research and dispels some common myths about evaluation. It highlights the current lack of robust evaluation of healthcare OR and makes the case for addressing this. It then proposes possible ways for building better empirical evaluations of OR interventions in healthcare.

尽管有越来越多的论文报道了运筹学(OR)在医疗保健领域的应用,但仍然很少有实证证据表明运筹学改善了医疗保健的实际提供。没有这样的证据,就很难向医疗保健受众证明运筹学的实用性,也很难学习和不断改进我们的方法。为了取得进展,我们需要通过认真的实证评估,建立有关手术室是否以及如何改善医疗服务的证据基础。本立场文件回顾了医疗保健改进研究中的评估标准,并消除了一些关于评估的常见误解。它强调了目前缺乏对医疗保健手术的有力评估,并提出了解决这一问题的理由。然后,它提出了对医疗保健领域的手术室干预措施进行更好的实证评估的可行方法。
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引用次数: 0
A discrete-event simulation model of the kidney transplantation system in Rajasthan, India. 印度拉贾斯坦邦肾移植系统的离散事件模拟模型。
IF 1.8 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-11-28 eCollection Date: 2022-01-01 DOI: 10.1080/20476965.2020.1848355
Mohd Shoaib, Utkarsh Prabhakar, Sumit Mahlawat, Varun Ramamohan

We present a discrete-event simulation model of the kidney transplantation system in an Indian state, Rajasthan. Organs are generated across the state based on the organ donation rate among the general population, and are allocated to patients on the kidney transplantation waitlist. The organ allocation algorithm is developed using official guidelines published for kidney transplantation, and model parameters were estimated using publicly available data to the extent possible. Transplantation outcomes generated by the model include: (a) the probabilities of a patient receiving an organ within one to 5 years of registration and (b) the average number of deaths per year due to lack of donated organs. Simulation experiments involving observing the effect of increasing the organ arrival rate and establishing additional transplantation centres on transplantation outcomes are also conducted. We also demonstrate the use of such a model to optimally locate additional transplantation centres using simulation optimisation methods.

我们提出了印度拉贾斯坦邦肾移植系统的离散事件模拟模型。器官是根据普通人群的器官捐献率在全州范围内产生的,并分配给肾移植等待名单上的患者。器官分配算法是根据官方发布的肾移植指南开发的,模型参数是尽可能使用公开可用的数据估计的。该模型产生的移植结果包括:(a)患者在登记后一至五年内接受器官的概率和(b)由于缺乏捐赠器官而每年死亡的平均人数。还进行了模拟实验,观察增加器官到达率和建立额外的移植中心对移植结果的影响。我们还演示了使用这样的模型,以最佳地定位额外的移植中心使用模拟优化方法。
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引用次数: 0
Increasing cardio-thoracic productivity at Erasmus MC. 提高Erasmus MC的心肺功能。
IF 1.8 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-11-26 eCollection Date: 2022-01-01 DOI: 10.1080/20476965.2020.1848357
Maartje Zonderland, Jos Bekkers, Jasper van Bommel, Maarten Ter Horst, Wouter van Leeuwen, Femke van den Wall Bake, Willem Wiegersma, Ad Bogers

The Thoraxcenter of Erasmus MC started an improvement project in 2015 in order to increase the number of open-heart surgeries by 150 for three consecutive years (450 in total, +46%), and to decrease the access time from 12-14 to 2-3 weeks by the end of 2016. This was required to attain economy of scale in a highly competitive market. In this paper we describe the first year of the project, focusing on its structure and interventions taken, resulting in 165 additional open-heart surgeries carried out in 2016 and a significantly shorter access time of 2-3 weeks.

2015年,Erasmus MC的胸腔中心启动了一项改善项目,目标是连续三年增加150例心内直视手术(总计450例,+46%),并在2016年底将就诊时间从12-14周减少到2-3周。这是在竞争激烈的市场中实现规模经济所必需的。在本文中,我们描述了该项目的第一年,重点介绍了其结构和采取的干预措施,结果在2016年进行了165例额外的心内直视手术,并大大缩短了2-3周的就诊时间。
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引用次数: 1
Secondary Household Covid-19 Transmission Modelling of Students Returning Home from University 高校返乡学生Covid-19二次家庭传播模型研究
IF 1.8 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-11-13 DOI: 10.1101/2020.11.11.20229559
Paul Robert Harper, Joshua W. Moore, Thomas E. Woolley
We estimate the number of secondary Covid-19 infections caused by potentially infectious students returning from university to private homes with other occupants. Using a Monte-Carlo method and data derived from UK sources, we predict that an infectious student would, on average, infect 0.94 other household members. Or, as a rule of thumb, each infected student would generate (just less than) one secondary within-household infection. The total number of secondary cases for all returning students is dependent on the virus prevalence within the student population at the time of their departure from campus back home. Correspondingly, we provide results for prevalence ranging from 0.5% to 15%, which is based on observed minimum and maximum estimates from Cardiff University's asymptomatic testing service. Although the proposed estimation method is general and robust, the results are sensitive to the input data. We therefore provide Matlab code and a helpful online app (http://bit.ly/Secondary_infections_app) that can be used to estimate numbers of secondary infections based on local parameter values
我们估计了由潜在传染性学生从大学返回私人住宅与其他居住者引起的继发性Covid-19感染的数量。使用蒙特卡罗方法和来自英国的数据,我们预测一个有传染性的学生平均会感染0.94名其他家庭成员。或者,根据经验,每个受感染的学生将在家庭内部产生(略少于)一次继发性感染。所有返校学生的继发性病例总数取决于他们离开校园返回家园时学生群体中的病毒流行情况。相应地,我们提供的患病率范围为0.5%至15%,这是基于卡迪夫大学无症状检测服务观察到的最小和最大估计值。虽然所提出的估计方法具有通用性和鲁棒性,但其结果对输入数据比较敏感。因此,我们提供了Matlab代码和一个有用的在线应用程序(http://bit.ly/Secondary_infections_app),可用于根据本地参数值估计二次感染的数量
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引用次数: 0
Outcomes of managing healthcare services using the Theory of Constraints: A systematic review. 使用约束理论管理医疗服务的结果:系统回顾。
IF 1.8 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-10-06 eCollection Date: 2022-01-01 DOI: 10.1080/20476965.2020.1813056
Gustavo M Bacelar-Silva, James F Cox, Pedro Pereira Rodrigues
ABSTRACT Despite ever-increasing resources devoted to healthcare, lack of capacity and timeliness are still chronic problems worldwide. This systematic review aims to present an overview of the Theory of Constraints (TOC) implementations in healthcare services and their outcomes. We analysed 42 TOC implementations (15 full-text articles, 12 video proceedings, and 2 theses/disserations) from major scientific electronic databases and TOC International Certification Organization Conferences. All implementations reported positive outcomes, both tangible and intangible. The two main improvements reported by authors were in productivity (98%; n = 41) – more patients treated – and in the timeliness of care (83%; n = 35). Furthermore, the selected studies reported dramatic improvements: 50% mean reductions in patient waiting time; 38% reduction in patient length of stay; 43% mean increase in operating room productivity and 34% mean increase in throughput. TOC implementations attained positive results in all levels of the health and social care chain. Most TOC recommendations and changes showed almost immediate results and required little or no additional cost to implement. Evidence supports TOC as a promising solution for the chronic healthcare problem, improving quality and timeliness, both necessary conditions for providing effective healthcare.
尽管用于医疗保健的资源不断增加,但缺乏能力和及时性仍然是世界各地的长期问题。本系统综述旨在概述医疗服务中的约束理论(TOC)实施及其结果。我们分析了来自主要科学电子数据库和TOC国际认证组织会议的42个TOC实施(15篇全文文章、12篇视频会议记录和2篇论文/论文)。所有实施都报告了有形和无形的积极成果。作者报告的两个主要改善是生产力(98%;n=41)——接受治疗的患者更多——和护理的及时性(83%;n=35)。此外,选定的研究报告了显著的改善:患者等待时间平均减少50%;患者住院时间缩短38%;手术室生产力平均提高43%,吞吐量平均提高34%。TOC的实施在卫生和社会护理链的各个层面都取得了积极成果。大多数技术选择委员会的建议和改变几乎立即产生效果,执行起来几乎不需要或根本不需要额外费用。有证据支持TOC是解决慢性医疗保健问题的一个有前景的解决方案,它提高了质量和及时性,这两个都是提供有效医疗保健的必要条件。
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引用次数: 7
Patient-held health IT adoption across the primary-secondary care interface: a Normalisation Process Theory perspective. 患者持有的医疗信息技术在初级-二级护理界面的采用:标准化过程理论视角。
IF 1.8 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-09-29 eCollection Date: 2022-01-01 DOI: 10.1080/20476965.2020.1822146
Stephen McCarthy, Ciara Fitzgerald, Laura Sahm, Colin Bradley, Elaine K Walsh

Patient-held Health Information Technologies (HIT) can reduce medical error by improving communication between patients and the healthcare team. Despite the proposed benefits, the roll-out of patient-held HIT solutions remains nascent, leaving considerable gaps in our understanding of the adoption challenges inherent. This paper adopts Normalisation Process Theory to study the factors which support or impede the adoption and "normalisation" of patient-held HIT, particularly across the primary-secondary care interface. The authors conducted an in-depth case study of HIT adoption across four GP practices, and the wards of a 350 bed hospital. 35 semi-structured interviews were completed. Findings point towards both user-specific and network-specific factors as significant challenges to normalisation across primary-secondary care. This includes factors related to interactional workability, skill set workability, relational integration, and contextual integration. We also discuss challenges specific to patient-held HIT adoption e.g., understanding the patient/clinician experience, supporting informal clinician networks, and spanning across IT boundaries.

患者持有的医疗信息技术(HIT)可以通过改善患者和医疗团队之间的沟通来减少医疗错误。尽管提出了这些好处,但患者持有的医疗保健解决方案的推广仍处于起步阶段,在我们对采用固有挑战的理解上留下了相当大的差距。本文采用正常化过程理论来研究支持或阻碍采用和“正常化”的患者持有的HIT的因素,特别是在初级和二级保健界面。作者进行了一个深入的案例研究,在四个全科医生的做法,和350个床位的医院病房采用HIT。完成了35次半结构化访谈。研究结果指出,用户特定因素和网络特定因素都是初级和二级保健正常化的重大挑战。这包括与交互可操作性、技能集可操作性、关系集成和上下文集成相关的因素。我们还讨论了采用患者持有的医疗信息技术所面临的具体挑战,例如,理解患者/临床医生的经验,支持非正式的临床医生网络,以及跨越IT边界。
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引用次数: 2
Variation of quantified infection rates of mixed samples to enhance rapid testing during an epidemic. 流行病期间混合样本的定量感染率变化以加强快速检测。
IF 1.8 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-09-13 eCollection Date: 2021-01-01 DOI: 10.1080/20476965.2020.1817801
Usama Kadri
ABSTRACT Rapid testing of appropriate samples from patients suspected for a disease during an epidemic, such as the current Coronavirus outbreak, is of a great importance for disease management and control. We propose a method to enhance processing large amounts of collected samples. The method is based on mixing samples in testing tubes (pooling) in a specific configuration, as opposed to testing single samples in each tube, and recognise infected samples from variations of the total infection rates in each tube. To illustrate the efficiency of the suggested method, we carry out numerical tests for actual scenarios under various test conditions. Applying the proposed method allows testing many more patients using the same number of testing tubes, where all positives are identified with no false negatives, and no need for independent testing, and the effective testing time can be reduced drastically even when the uncertainty in the test is relatively high.
在疫情期间(如当前的冠状病毒疫情),对疑似疾病患者的适当样本进行快速检测,对于疾病管理和控制具有重要意义。我们提出了一种方法,以提高处理大量收集的样品。该方法基于在特定配置的试管中混合样本(池化),而不是在每个试管中测试单个样本,并从每个试管中总感染率的变化中识别受感染样本。为了说明所提方法的有效性,我们在各种测试条件下对实际场景进行了数值测试。应用所提出的方法可以使用相同数量的试管检测更多的患者,其中所有阳性都被识别,没有假阴性,不需要独立检测,并且即使在检测的不确定性相对较高时,有效检测时间也可以大大缩短。
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引用次数: 3
Identifying user assistance systems for radiotherapy to increase efficiency and help saving lives. 确定用于放射治疗的用户辅助系统,以提高效率,帮助挽救生命。
IF 1.2 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-08-30 eCollection Date: 2021-01-01 DOI: 10.1080/20476965.2020.1803148
Ralf Müller-Polyzou, Melanie Reuter-Oppermann, Anke Engbert, Raphael Schmidt

Increasing efficiency and reducing risk in radiotherapy cancer treatment is of high importance. User assistance systems within a digitally connected radiotherapy environment can support all involved professionals to perform their individual tasks faster and better. This paper presents a qualitative analysis of radiotherapy workflows and a corresponding process modelling in order to identify hypothetical user assistance systems for specific process activities. In addition, the results of an empirical study on the identified systems are presented together with derived requirements and design principles for these systems. A structured online survey with 50 medical physicists in Germany has been conducted. Among others the acceptance, the increase of perceived efficiency and the risk reduction while using the assistance systems are analysed and discussed. The results support the creation of value adding user assistance systems for radiotherapy that improve efficiency, reduce treatment risks and reach high user acceptance levels.

提高癌症放射治疗的效率和降低风险至关重要。在数字化连接的放射治疗环境中,用户辅助系统可以支持所有相关专业人员更快更好地完成各自的任务。本文对放射治疗工作流程进行了定性分析,并建立了相应的流程模型,以便为特定流程活动确定假设的用户辅助系统。此外,还介绍了对所确定系统的实证研究结果,以及这些系统的衍生需求和设计原则。对德国 50 名医学物理学家进行了结构化在线调查。除其他外,还分析和讨论了使用辅助系统时的接受程度、感知效率的提高和风险的降低。调查结果表明,为提高效率、降低治疗风险和达到较高的用户接受度,可创建具有附加值的放射治疗用户辅助系统。
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引用次数: 0
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Health Systems
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