Objectives: To compare the levels of postnatal depression experienced by Arab women in Jordan and the United States (USA) and the impact of social support during the COVID-19 pandemic. Methodology: Participants were recruited through online survey links and social media channels, as well as face to face. A sample comprising 434 women in the postnatal period participated in the study that included Arab women in the USA and Jordan women, responding to a comprehensive questionnaire that encompassed inquiries about their pandemic status, demographic characteristics, postnatal depression, and social support. CES-D depression scale was used to determine the level of depression. Findings: The depression mean score among women in the postnatal period from Jordan was 24.90±4.14 and the depression mean score among Arab women in the USA was 27.70±4.49. The prevalence of depression among Jordanian women was 52.8% and the prevalence of depression among Arab American women was 73.0%. There is a significant difference between both groups in depression during the postnatal period with more prevalence among Arab American women (t=7.64, p=.010). There are no significant differences between groups in tangible and actual social support among both groups (t=1.50, p=.127). Conclusions: This nationwide study conducted among postnatal women in Jordan has shed light on several critical findings. Our study found that Arab women in the USA were suffering from more depression compared to Jordanian women. Moreover, our research highlighted a significant inverse relationship between social support and postnatal depression, indicating that as social support increased, levels of depression decreased among women in the postnatal period.
{"title":"Postnatal depression and social support during the COVID-19 pandemic among Arab women in Jordan and the United States: A comparative study","authors":"S. Abuhammad, Sarah Abu Al-Rub, Wael Al-Delaimy","doi":"10.29333/ejgm/13965","DOIUrl":"https://doi.org/10.29333/ejgm/13965","url":null,"abstract":"Objectives: To compare the levels of postnatal depression experienced by Arab women in Jordan and the United States (USA) and the impact of social support during the COVID-19 pandemic. Methodology: Participants were recruited through online survey links and social media channels, as well as face to face. A sample comprising 434 women in the postnatal period participated in the study that included Arab women in the USA and Jordan women, responding to a comprehensive questionnaire that encompassed inquiries about their pandemic status, demographic characteristics, postnatal depression, and social support. CES-D depression scale was used to determine the level of depression. Findings: The depression mean score among women in the postnatal period from Jordan was 24.90±4.14 and the depression mean score among Arab women in the USA was 27.70±4.49. The prevalence of depression among Jordanian women was 52.8% and the prevalence of depression among Arab American women was 73.0%. There is a significant difference between both groups in depression during the postnatal period with more prevalence among Arab American women (t=7.64, p=.010). There are no significant differences between groups in tangible and actual social support among both groups (t=1.50, p=.127). Conclusions: This nationwide study conducted among postnatal women in Jordan has shed light on several critical findings. Our study found that Arab women in the USA were suffering from more depression compared to Jordanian women. Moreover, our research highlighted a significant inverse relationship between social support and postnatal depression, indicating that as social support increased, levels of depression decreased among women in the postnatal period.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139125756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Martono, Sudiro Sudiro, Satino Satino, Siti Lestari, Insiyah Insiyah, Sri Martuti, Pradita Ayu Fernanda
Objectives: The purpose of this study was to identify and analyze the predictors of mortality in the cases of hemorrhagic stroke with brain herniation of hospitalized patients. Methods: In this retrospective cohort study, we analyzed 1,330 cases of hemorrhagic stroke with brain herniation from January 2015 to October 2020, and used logistic regression to identify the cause of death of hemorrhagic stroke with brain herniation. Results: A total of 1,330 stroke patients with brain herniation were identified. The mean age was 63.40±61.00 years and 56.50% of them were male. A total of 78.80% of the observed patients were discharged directly after recovery, 2.00% were discharged at the personal/family request, and number of patients who died after being treated 19.20% died (30.90% died after being treated for <48 hours, and 69.10% died after being treated for ³48 hours). Patients who were ³65 years old had more tendency to die than those who were younger, with a 95% confidence interval (CI) 6,859-26,486; p=0.001). The higher the systolic and diastolic blood pressure was, the greater the probability of dying after hospitalization (odds ratio [OR] 2.340, CI 1.334-4.104, p=0.022, OR 2.110, CI 1.042-4.273, p=0.026), the lower Glasgow coma scale (GCS) score at admission (<5), the more tendency for a patient to die (OR 1.376, CI 0.816–2.320, p=0.038) would be. Conclusions: Patient’s age ³65 years, high systolic blood pressure, high diastolic blood pressure, and GCS score <5 are predictors associated with the mortality of hemorrhagic stroke with brain herniation. The implications of these findings, if confirmed in prospective studies, would raise important policy considerations both in hospitals and at the overall health level, particularly regarding post-acute care.
{"title":"Prediction of factors influencing hemorrhagic stroke death with brain herniation in teaching hospitals","authors":"M. Martono, Sudiro Sudiro, Satino Satino, Siti Lestari, Insiyah Insiyah, Sri Martuti, Pradita Ayu Fernanda","doi":"10.29333/ejgm/13899","DOIUrl":"https://doi.org/10.29333/ejgm/13899","url":null,"abstract":"Objectives: The purpose of this study was to identify and analyze the predictors of mortality in the cases of hemorrhagic stroke with brain herniation of hospitalized patients. Methods: In this retrospective cohort study, we analyzed 1,330 cases of hemorrhagic stroke with brain herniation from January 2015 to October 2020, and used logistic regression to identify the cause of death of hemorrhagic stroke with brain herniation. Results: A total of 1,330 stroke patients with brain herniation were identified. The mean age was 63.40±61.00 years and 56.50% of them were male. A total of 78.80% of the observed patients were discharged directly after recovery, 2.00% were discharged at the personal/family request, and number of patients who died after being treated 19.20% died (30.90% died after being treated for <48 hours, and 69.10% died after being treated for ³48 hours). Patients who were ³65 years old had more tendency to die than those who were younger, with a 95% confidence interval (CI) 6,859-26,486; p=0.001). The higher the systolic and diastolic blood pressure was, the greater the probability of dying after hospitalization (odds ratio [OR] 2.340, CI 1.334-4.104, p=0.022, OR 2.110, CI 1.042-4.273, p=0.026), the lower Glasgow coma scale (GCS) score at admission (<5), the more tendency for a patient to die (OR 1.376, CI 0.816–2.320, p=0.038) would be. Conclusions: Patient’s age ³65 years, high systolic blood pressure, high diastolic blood pressure, and GCS score <5 are predictors associated with the mortality of hemorrhagic stroke with brain herniation. The implications of these findings, if confirmed in prospective studies, would raise important policy considerations both in hospitals and at the overall health level, particularly regarding post-acute care.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139125965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad A Altarifi, Omar Obeidat, Ahmad Guzu, Amr Said, Mahmoud Albakheet, Ahmad Makkawi, Zuheir Hasan, Mohammed Azab, M. Alotaibi, K. Kheirallah, T. Saleh
Introduction: Pregabalin and gabapentin (or gabapentanoids) have been reported to be abused for potentially euphoric effects. Objectives: In this work, we conducted a descriptive, cross-sectional study among university students from Jordan utilizing a structured online questionnaire. Results: 96.1% of the participants indicated no previous or current use of gabapentanoids, while 53 (3.9%) self-reported previous or current use (ever-use) of any of both drugs. The rate of abuse was higher among males and older students’ groups. 50.9% of drug users did not obtain a valid prescription. Most abusers indicated that their use of both drugs was for non-medical reasons (39.6%), and 69.8% students used both drugs despite being aware of their adverse effects. Hypersomnia was the most reported adverse effect. However, most participants (64.2%) did not report any withdrawal symptoms upon drug discontinuation. Marijuana/hashish was the most consumed substance with gabapentanoids. Conclusions: Our results invite for further prescribed drug control and increasing the awareness against drug abuse among the youth in Jordan.
{"title":"Pregabalin and gabapentin abuse among university students in Jordan: A cross sectional study","authors":"Ahmad A Altarifi, Omar Obeidat, Ahmad Guzu, Amr Said, Mahmoud Albakheet, Ahmad Makkawi, Zuheir Hasan, Mohammed Azab, M. Alotaibi, K. Kheirallah, T. Saleh","doi":"10.29333/ejgm/14021","DOIUrl":"https://doi.org/10.29333/ejgm/14021","url":null,"abstract":"Introduction: Pregabalin and gabapentin (or gabapentanoids) have been reported to be abused for potentially euphoric effects. Objectives: In this work, we conducted a descriptive, cross-sectional study among university students from Jordan utilizing a structured online questionnaire. Results: 96.1% of the participants indicated no previous or current use of gabapentanoids, while 53 (3.9%) self-reported previous or current use (ever-use) of any of both drugs. The rate of abuse was higher among males and older students’ groups. 50.9% of drug users did not obtain a valid prescription. Most abusers indicated that their use of both drugs was for non-medical reasons (39.6%), and 69.8% students used both drugs despite being aware of their adverse effects. Hypersomnia was the most reported adverse effect. However, most participants (64.2%) did not report any withdrawal symptoms upon drug discontinuation. Marijuana/hashish was the most consumed substance with gabapentanoids. Conclusions: Our results invite for further prescribed drug control and increasing the awareness against drug abuse among the youth in Jordan.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139128488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ghaith M Al-Taani, S. Al‐Azzam, K. Alzoubi, W. Sweileh, S. Muflih
Background: The incidence of polypharmacy is increasing owing to population aging and the associated presence of multiple comorbidities. This study aimed to provide an extensive overview of the history and development of the scientific literature on polypharmacy. Methods: Data were gathered from the comprehensive Scopus database and assessed using various bibliometric methods, including analyses of citations, growth patterns, and key contributors in the field. Results: A notable upward trend in the publication rate of polypharmacy research was observed throughout the study period (1976-2022). Journal of the American Geriatrics Society emerged as the predominant platform for disseminating polypharmacy-related findings. Hughes CM from Queen’s University Belfast, the United Kingdom (UK), emerged as the most prolific author in this field. Most articles were authored by researchers affiliated with institutions in the United States (n=267), the UK (n=92), and Italy (n=72). Conclusion: This study provides compelling evidence of the escalating interest in polypharmacy and momentum in related research, highlighting the crucial publication-related aspects and indicators in this field. The findings underline the value of bibliometric analyses as a tool for healthcare professionals. The wide dissemination, influence, and visibility of polypharmacy research in reputable scientific journals emphasize the urgent clinical need for addressing polypharmacy concerns and encourage further exploration in this area.
{"title":"Polypharmacy in the elderly: A bibliometric and visualization analysis","authors":"Ghaith M Al-Taani, S. Al‐Azzam, K. Alzoubi, W. Sweileh, S. Muflih","doi":"10.29333/ejgm/13901","DOIUrl":"https://doi.org/10.29333/ejgm/13901","url":null,"abstract":"Background: The incidence of polypharmacy is increasing owing to population aging and the associated presence of multiple comorbidities. This study aimed to provide an extensive overview of the history and development of the scientific literature on polypharmacy. Methods: Data were gathered from the comprehensive Scopus database and assessed using various bibliometric methods, including analyses of citations, growth patterns, and key contributors in the field. Results: A notable upward trend in the publication rate of polypharmacy research was observed throughout the study period (1976-2022). Journal of the American Geriatrics Society emerged as the predominant platform for disseminating polypharmacy-related findings. Hughes CM from Queen’s University Belfast, the United Kingdom (UK), emerged as the most prolific author in this field. Most articles were authored by researchers affiliated with institutions in the United States (n=267), the UK (n=92), and Italy (n=72). Conclusion: This study provides compelling evidence of the escalating interest in polypharmacy and momentum in related research, highlighting the crucial publication-related aspects and indicators in this field. The findings underline the value of bibliometric analyses as a tool for healthcare professionals. The wide dissemination, influence, and visibility of polypharmacy research in reputable scientific journals emphasize the urgent clinical need for addressing polypharmacy concerns and encourage further exploration in this area.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139126694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes is a chronic metabolic disease, which has affected approximately 10.5% of the global population [1]. The most frequent types of diabetes are type-1 and type-2. The third frequent type is gestational diabetes. The pathogenicity of diabetes is multifactorial and involves various factors such as genetic, food, stress, environmental pollutants, and others, in most of the cases combination of two or more factors are noticed. Comparative studies of the influence of palm oil on the activity of xanthine oxidase (XOD) and free radicals in liver and blood. The research compared the effect of palm oil on carbohydrate metabolism in male rats: in young rats and adult rats. The research compared the effect of palm oil on free radicals in male rats: in adults and juvenile rats. Experimental animal body weight change research, 30 days after palm oil treatment. For this scientific research we utilized experimental animals of the male genus: mice of the Wistar type, small mice (45-60 g) and large mice (160-180 g). Experimental animals were divided into groups of six-eight experimental mice and details are shown in the corresponding part of the results. The results are shown in six figures and two tables. Results indicate an increase in the formation of free radicals in blood plasma, both in experimental juvenile mice and in experimental large mice under the influence of palm oil. Palm oil increases the activity of XOD in blood, both in small animals and in large experimental animals. Palm oil increases the formation of XOD in the black liver in both elderly groups. In all groups during the experiment there was an increase in body weight. Results from studies of the effect of palm oil on carbohydrate metabolism showed changes in glucose tolerance test. Current studies for the first time convincingly demonstrate the risk of using palm oil. Analysis of the results of two studies on XOD and carbohydrate metabolism showed a correlation between increased XOD levels and the development of prediabetes.
{"title":"Comparative studies of influence of palm oil on activity of xanthine oxidase and free radicals in liver and blood: Diabetes and metabolic syndrom","authors":"Besim Memedi","doi":"10.29333/ejgm/13876","DOIUrl":"https://doi.org/10.29333/ejgm/13876","url":null,"abstract":"Diabetes is a chronic metabolic disease, which has affected approximately 10.5% of the global population [1]. The most frequent types of diabetes are type-1 and type-2. The third frequent type is gestational diabetes. The pathogenicity of diabetes is multifactorial and involves various factors such as genetic, food, stress, environmental pollutants, and others, in most of the cases combination of two or more factors are noticed. Comparative studies of the influence of palm oil on the activity of xanthine oxidase (XOD) and free radicals in liver and blood. The research compared the effect of palm oil on carbohydrate metabolism in male rats: in young rats and adult rats. The research compared the effect of palm oil on free radicals in male rats: in adults and juvenile rats. Experimental animal body weight change research, 30 days after palm oil treatment. For this scientific research we utilized experimental animals of the male genus: mice of the Wistar type, small mice (45-60 g) and large mice (160-180 g). Experimental animals were divided into groups of six-eight experimental mice and details are shown in the corresponding part of the results. The results are shown in six figures and two tables. Results indicate an increase in the formation of free radicals in blood plasma, both in experimental juvenile mice and in experimental large mice under the influence of palm oil. Palm oil increases the activity of XOD in blood, both in small animals and in large experimental animals. Palm oil increases the formation of XOD in the black liver in both elderly groups. In all groups during the experiment there was an increase in body weight. Results from studies of the effect of palm oil on carbohydrate metabolism showed changes in glucose tolerance test. Current studies for the first time convincingly demonstrate the risk of using palm oil. Analysis of the results of two studies on XOD and carbohydrate metabolism showed a correlation between increased XOD levels and the development of prediabetes.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135192203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The current study aims to provide a comprehensive overview of the research landscape on the risk factors and preventive approaches to occupational musculoskeletal disorders (MSDs). Methods: A comprehensive search strategy was developed and used in the Scopus Database for the study period from 1993 to 2022. Results: A total of 1,132 articles underwent analysis and mapping. Scholars from the United States made the largest contribution, while the Danish institution “National Research Center for the Working Environment” ranked first in the field. The map showed that the nursing profession was the most researched profession with regard to occupational MSDs. The top-100 cited articles included research themes focusing on risk factors, interventions and preventive strategies, and specific body regions affected. Conclusions: More longitudinal research is needed to identify and confirm the causal relationship between different risk factors and occupational MSDs and more research is needed regarding the effectiveness of various interventional methods on occupational MSDs.
{"title":"Analysis and mapping of the research landscape on occupational musculoskeletal disorders with an emphasis on risk factors and preventive approaches (1993-2022)","authors":"Waleed M Sweileh","doi":"10.29333/ejgm/13662","DOIUrl":"https://doi.org/10.29333/ejgm/13662","url":null,"abstract":"<b>Objective: </b>The current study aims to provide a comprehensive overview of the research landscape on the risk factors and preventive approaches to occupational musculoskeletal disorders (MSDs).<br /> <b>Methods: </b>A comprehensive search strategy was developed and used in the Scopus Database for the study period from 1993 to 2022.<br /> <b>Results: </b>A total of 1,132 articles underwent analysis and mapping. Scholars from the United States made the largest contribution, while the Danish institution “<i>National Research Center for the Working Environment</i>” ranked first in the field. The map showed that the nursing profession was the most researched profession with regard to occupational MSDs. The top-100 cited articles included research themes focusing on risk factors, interventions and preventive strategies, and specific body regions affected.<br /> <b>Conclusions: </b>More longitudinal research is needed to identify and confirm the causal relationship between different risk factors and occupational MSDs and more research is needed regarding the effectiveness of various interventional methods on occupational MSDs.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134957499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Safa Alqudah, Alia Alqudah, Maha Zaitoun, Hussein Alqassem
Introduction: The knowledge and attitudes about genetic hearing loss are essential to prevent more hearing loss incidences in societies. However, limited studies have compared the knowledge and attitude toward genetic technology between parents of normal and impaired-hearing children. Methods: A descriptive, cross-sectional study was performed involving105 parents with one or more children having a hearing impairment and 204 control parents with children having normal hearing. Parents completed surveys designed to investigate their knowledge and attitudes about the genetic basis of hearing impairment and recent technologies. Descriptive and inferential statistics were used to measure response differences between the two groups. Results: Both groups shared the same level of knowledge, with the average knowledge scores of parents with normal-hearing children (9.53/19±2.56 points) resembling those of parents with hearing-impaired children (10.08/19±3.17 points; F(1, 307)=-2.17, p=0.14). Moreover, parents had limited information about the genetic basis of hearing loss, specifically in estimating the recurrence of congenital hearing loss (n=26 of 105, 24.76%)and misunderstanding inheritance paradigms (n=24 of 105, 22.86%). Regardless of having children with auditory issues, parents expressed positive attitudes towards genetic testing. Conclusions: These findings suggest that more genetic specialists are needed to educate families of children with hearing loss about the genetic attributes of hearing impairment and the significance of genetic technology.
{"title":"Parental knowledge and attitudes towards hereditary hearing loss and genetic technology","authors":"Safa Alqudah, Alia Alqudah, Maha Zaitoun, Hussein Alqassem","doi":"10.29333/ejgm/13813","DOIUrl":"https://doi.org/10.29333/ejgm/13813","url":null,"abstract":"<b>Introduction:</b> The knowledge and attitudes about genetic hearing loss are essential to prevent more hearing loss incidences in societies. However, limited studies have compared the knowledge and attitude toward genetic technology between parents of normal and impaired-hearing children.<br /> &nbsp;<b>Methods:</b> A descriptive, cross-sectional study was performed involving<b> </b>105 parents with one or more children having a hearing impairment and 204 control parents with children having normal hearing. Parents completed surveys designed to investigate their knowledge and attitudes about the genetic basis of hearing impairment and recent technologies. Descriptive and inferential statistics were used to measure response differences between the two groups.<br /> <b>Results:</b> Both groups shared the same level of knowledge, with the average knowledge scores of parents with normal-hearing children (9.53/19±2.56 points) resembling those of parents with hearing-impaired children (10.08/19±3.17 points; F(1, 307)=-2.17, p=0.14). Moreover, parents had limited information about the genetic basis of hearing loss, specifically in estimating the recurrence of congenital hearing loss (n=26 of 105, 24.76%)and misunderstanding inheritance paradigms (n=24 of 105, 22.86%). Regardless of having children with auditory issues, parents expressed positive attitudes towards genetic testing.<br /> <b>Conclusions:</b> These findings suggest that more genetic specialists are needed to educate families of children with hearing loss about the genetic attributes of hearing impairment and the significance of genetic technology.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135111240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Hemostasis research lacked novel platform assays for hemostatic disorder diagnosis. The current review study’s goal is to compare various assays for evaluating the novel hemostatic techniques used in the diagnosis of coagulation disturbances and to highlight each method’s strongest and weakest points. Methods: The PRISMA guidelines and the recommendations for observational studies in epidemiology were both followed in the current systematic review. The PRISMA-compliant electronic databases (PubMed), a novel platform for evaluating hemostasis, were searched using the keywords. The electronic databases (PubMed), a cutting-edge platform to assess hemostasis, were searched using the keywords. Articles published between December 2016 and December 2021 were only included in searches; original articles were written in English. In order to assess hemostasis studies, we gathered bibliographies of abstracts that were published on the new and more effective application assays for assessments of hemostasis disorders. Results: Following the removal of duplicates, articles were determined by examining the titles and abstracts. Disagreements were resolved through consensus and the application of novel hemostatic analysis methods. Then independently reviewed the relevant studies of the recognized records (n=503), excluding duplicates (n=9) and irrelevant studies (n=249). The remaining 254 studies were read in their entirety, the data from the seven included studies had been extracted. Conclusions: When expressed as an anticoagulant for the in vivo assessment of on the complement system, nanotechnology-based study was more effective in some laboratory tests, and flow cytometer evaluation could be a promising platform approach for use in hemostasis management.
{"title":"New and more effective application assays for hemostatic disorder assessment: A systematic review","authors":"Faisal M Al-Zahrani","doi":"10.29333/ejgm/13570","DOIUrl":"https://doi.org/10.29333/ejgm/13570","url":null,"abstract":"Background: Hemostasis research lacked novel platform assays for hemostatic disorder diagnosis. The current review study’s goal is to compare various assays for evaluating the novel hemostatic techniques used in the diagnosis of coagulation disturbances and to highlight each method’s strongest and weakest points.\u0000Methods: The PRISMA guidelines and the recommendations for observational studies in epidemiology were both followed in the current systematic review. The PRISMA-compliant electronic databases (PubMed), a novel platform for evaluating hemostasis, were searched using the keywords. The electronic databases (PubMed), a cutting-edge platform to assess hemostasis, were searched using the keywords. Articles published between December 2016 and December 2021 were only included in searches; original articles were written in English. In order to assess hemostasis studies, we gathered bibliographies of abstracts that were published on the new and more effective application assays for assessments of hemostasis disorders.\u0000Results: Following the removal of duplicates, articles were determined by examining the titles and abstracts. Disagreements were resolved through consensus and the application of novel hemostatic analysis methods. Then independently reviewed the relevant studies of the recognized records (n=503), excluding duplicates (n=9) and irrelevant studies (n=249). The remaining 254 studies were read in their entirety, the data from the seven included studies had been extracted.\u0000Conclusions: When expressed as an anticoagulant for the in vivo assessment of on the complement system, nanotechnology-based study was more effective in some laboratory tests, and flow cytometer evaluation could be a promising platform approach for use in hemostasis management.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49302985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sovia Salamah, Ristra Ramadhani, Mega Rizkya Arfiana, Ibrahim Syamsuri, David Nugraha, Fauzan Illavi, Asiyah Nida Khafiyya, Astri Dewayani, M Rifqi Rokhman, Firas Farisi Alkaff
Background: TheIndonesian Government launched chronic disease management program (PROLANIS) with the aim of improving clinical outcomes and preventing disease complications of patients with type 2 diabetes (T2D). During the coronavirus disease 2019 (COVID-19) pandemic, the overwhelmed healthcare system shifted resources away from non-communicable diseases in the attempt to mitigate it. Thus, the implementation of PROLANIS during the COVID-19 pandemic might not be as optimal as before the pandemic era, leading to worse clinical outcomes. This pilot study aims to evaluate the impact of the COVID-19 pandemic on PROLANIS in rural areas by analyzing the changes of metabolic control and renal function parameters. Methods: This study used data from three PROLANIS groups report in rural areas in East Java Province, Indonesia. Study population was PROLANIS participants who came for six-month-evaluation in December 2019 (T0), June 2020 (T1), and December 2020 (T2). Evaluated metabolic control parameters were body mass index (BMI), blood pressure, hemoglobin A1C (HbA1C), total cholesterol (TC), high-density lipid, low-density lipid, and triglyceride (TG), whereas evaluated renal function parameters were blood urea nitrogen, serum creatinine, and urinary albumin. Independent t-test and Wilcoxon signed-rank test were used for statistical analyses. p-value <0.05 was considered statistically significant. Results: Among 52 PROLANIS participants included in the analyses, four metabolic control parameters (BMI, blood pressure, TC, and TG) and all renal function parameters significantly worsened right after the pandemic started but improved 6 months afterwards. Meanwhile, HbA1C continuously worsened throughout the study period, albeit statistically insignificant. Conclusions: The metabolic control and renal function parameters in our study population deteriorates especially in the beginning of the COVID-19 pandemic.
{"title":"Impact of the COVID-19 pandemic on the outcomes of Indonesian chronic disease management program","authors":"Sovia Salamah, Ristra Ramadhani, Mega Rizkya Arfiana, Ibrahim Syamsuri, David Nugraha, Fauzan Illavi, Asiyah Nida Khafiyya, Astri Dewayani, M Rifqi Rokhman, Firas Farisi Alkaff","doi":"10.29333/ejgm/13661","DOIUrl":"https://doi.org/10.29333/ejgm/13661","url":null,"abstract":"<b>Background: </b>The<i> </i>Indonesian Government launched chronic disease management program (PROLANIS) with the aim of improving clinical outcomes and preventing disease complications of patients with type 2 diabetes (T2D). During the coronavirus disease 2019 (COVID-19) pandemic, the overwhelmed healthcare system shifted resources away from non-communicable diseases in the attempt to mitigate it. Thus, the implementation of PROLANIS during the COVID-19 pandemic might not be as optimal as before the pandemic era, leading to worse clinical outcomes. This pilot study aims to evaluate the impact of the COVID-19 pandemic on PROLANIS in rural areas by analyzing the changes of metabolic control and renal function parameters.<br /> <b>Methods:</b> This study used data from three PROLANIS groups report in rural areas in East Java Province, Indonesia. Study population was PROLANIS participants who came for six-month-evaluation in December 2019 (T0), June 2020 (T1), and December 2020 (T2). Evaluated metabolic control parameters were body mass index (BMI), blood pressure, hemoglobin A1C (HbA1C), total cholesterol (TC), high-density lipid, low-density lipid, and triglyceride (TG), whereas evaluated renal function parameters were blood urea nitrogen, serum creatinine, and urinary albumin. Independent t-test and Wilcoxon signed-rank test were used for statistical analyses. p-value &lt;0.05 was considered statistically significant.<br /> <b>Results:</b> Among 52 PROLANIS participants included in the analyses, four metabolic control parameters (BMI, blood pressure, TC, and TG) and all renal function parameters significantly worsened right after the pandemic started but improved 6 months afterwards. Meanwhile, HbA1C continuously worsened throughout the study period, albeit statistically insignificant.<br /> <b>Conclusions: </b>The metabolic control and renal function parameters in our study population deteriorates especially in the beginning of the COVID-19 pandemic.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134957373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The purpose of this systematic review and meta-analysis study was to compare various caesarean delivery methods. Methods: A search for available articles published since January 2023 was accomplished in PubMed, Medline, Embase, and Cochrane literature databases. The search method that encompassed all pertinent publications was developed using terms from the medical subject headings thesaurus and keywords from related literature. We also used the PICO method (where P is population, I is intervention, C is comparator/control, and O is outcome for our study) to establish research question. Whereas Cochrane handbook of “systematic reviews of interventions” was used for risk of bias assessment. Results: The results showed a significant difference in patient gratification between the gentle/natural/skin-to-skin contact caesarean and the traditional/conventional/standard caesarean. In assessing the satisfaction with delivery mode, the mean variance for these studies similarly revealed a significant difference between the natural caesarean and the conventional one. A skin-to-skin contact caesarean delivery takes less time to start nursing than a conventional delivery, according to the results of the study on the time of breastfeeding initiation after a natural caesarean. There was a low-risk bias among the selected studies. Conclusions: As a result of greater satisfaction with delivering experience the natural caesarean delivery was most preferred method. The enhanced skin-to-skin contact and breastfeeding suggested that natural caesarean is beneficial over the conventional method.
{"title":"Comparison of different cesarean delivery techniques: A systematic review and meta-analysis","authors":"A. Yuldasheva, Gulzhakhan Omarova, Zhanara Begniyazova, Shynar Saduakassova, Elmira Makhmutova, Aliya Meirmanova","doi":"10.29333/ejgm/13590","DOIUrl":"https://doi.org/10.29333/ejgm/13590","url":null,"abstract":"Background: The purpose of this systematic review and meta-analysis study was to compare various caesarean delivery methods.\u0000Methods: A search for available articles published since January 2023 was accomplished in PubMed, Medline, Embase, and Cochrane literature databases. The search method that encompassed all pertinent publications was developed using terms from the medical subject headings thesaurus and keywords from related literature. We also used the PICO method (where P is population, I is intervention, C is comparator/control, and O is outcome for our study) to establish research question. Whereas Cochrane handbook of “systematic reviews of interventions” was used for risk of bias assessment.\u0000Results: The results showed a significant difference in patient gratification between the gentle/natural/skin-to-skin contact caesarean and the traditional/conventional/standard caesarean. In assessing the satisfaction with delivery mode, the mean variance for these studies similarly revealed a significant difference between the natural caesarean and the conventional one. A skin-to-skin contact caesarean delivery takes less time to start nursing than a conventional delivery, according to the results of the study on the time of breastfeeding initiation after a natural caesarean. There was a low-risk bias among the selected studies.\u0000Conclusions: As a result of greater satisfaction with delivering experience the natural caesarean delivery was most preferred method. The enhanced skin-to-skin contact and breastfeeding suggested that natural caesarean is beneficial over the conventional method.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45908984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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