Pub Date : 2022-06-13DOI: 10.1080/13619462.2022.2088517
L. Abrams
{"title":"The welfare state generation: women, agency and class in Britain since 1945","authors":"L. Abrams","doi":"10.1080/13619462.2022.2088517","DOIUrl":"https://doi.org/10.1080/13619462.2022.2088517","url":null,"abstract":"","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"36 1","pages":"482 - 484"},"PeriodicalIF":0.7,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42752619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-13DOI: 10.1080/13619462.2022.2088519
Gillian A. M. Mitchell
{"title":"The Beatles and Sixties Britain","authors":"Gillian A. M. Mitchell","doi":"10.1080/13619462.2022.2088519","DOIUrl":"https://doi.org/10.1080/13619462.2022.2088519","url":null,"abstract":"","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46244368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The interaction of immune cells and cytokines in the tumor microenvironment affects the development and prognosis of tumors with an unclear potential regulatory mechanism. Recent studies have elucidated the protumor role of Th22 cells and its lineage-specific cytokine IL-22 in different human cancers. The present study is aimed at investigating the biological effect of Th22 cells/IL-22 and its molecular mechanism in the pathogenesis process of non-small-cell lung cancer (NSCLC). It was initially found that Th22 cells were enriched in the peripheral blood of NSCLC patients. The level of Th22 cells in peripheral blood mononuclear cells (PBMCs) was positively correlated with the TNM stage, lymph node metastasis, and clinical tumor biomarkers. Furthermore, IL-22 not only antagonized the apoptosis inducing and cell cycle arresting effect by chemotherapy and molecular targeted drugs on NSCLC cell lines but also promoted tumor cell proliferation and tumor tissue growth. Moreover, IL-22 activated the JAK-STAT3/MAPK/AKT signaling pathway, both in vitro and in vivo. Conclusively, the present results confirm that Th22 cells/IL-22 may serve as a negative immune regulator in lung cancer.
{"title":"Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer.","authors":"Yinan Yao, Guangdie Yang, Guohua Lu, Jiani Ye, Luyun Cui, Zhu Zeng, Junjun Chen, Jianying Zhou","doi":"10.1155/2022/8071234","DOIUrl":"10.1155/2022/8071234","url":null,"abstract":"<p><p>The interaction of immune cells and cytokines in the tumor microenvironment affects the development and prognosis of tumors with an unclear potential regulatory mechanism. Recent studies have elucidated the protumor role of Th22 cells and its lineage-specific cytokine IL-22 in different human cancers. The present study is aimed at investigating the biological effect of Th22 cells/IL-22 and its molecular mechanism in the pathogenesis process of non-small-cell lung cancer (NSCLC). It was initially found that Th22 cells were enriched in the peripheral blood of NSCLC patients. The level of Th22 cells in peripheral blood mononuclear cells (PBMCs) was positively correlated with the TNM stage, lymph node metastasis, and clinical tumor biomarkers. Furthermore, IL-22 not only antagonized the apoptosis inducing and cell cycle arresting effect by chemotherapy and molecular targeted drugs on NSCLC cell lines but also promoted tumor cell proliferation and tumor tissue growth. Moreover, IL-22 activated the JAK-STAT3/MAPK/AKT signaling pathway, both <i>in vitro</i> and <i>in vivo</i>. Conclusively, the present results confirm that Th22 cells/IL-22 may serve as a negative immune regulator in lung cancer.</p>","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"26 1","pages":"8071234"},"PeriodicalIF":4.1,"publicationDate":"2022-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167127/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82434318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-28DOI: 10.1080/13619462.2022.2081549
J. Kirby
ABSTRACT This article examines how stress was used as a means of explaining and understanding the changes that were taking place in large sections of Britain’s workforce during the 1980s and 1990s. By bringing together personal accounts of how people understood and explained the effects of these adjustments on their everyday lives with the popular discourse of stress in the media, I will show how stress became a key means of interpreting the significant social and economic change that was occurring. It also brought about change in both working practices and the ways in which work and well-being were understood by both individual workers and their employers. I will also examine how newspaper reporting of stress suffered by public sector workers, particularly in the NHS and education, revealed the tensions underlying reforms in these areas and will argue that by focusing on worker experience of stress, such reporting effectively drew attention away from the underlying structural changes causing that stress.
{"title":"The stress of work and work of stress in Britain in the late twentieth century","authors":"J. Kirby","doi":"10.1080/13619462.2022.2081549","DOIUrl":"https://doi.org/10.1080/13619462.2022.2081549","url":null,"abstract":"ABSTRACT This article examines how stress was used as a means of explaining and understanding the changes that were taking place in large sections of Britain’s workforce during the 1980s and 1990s. By bringing together personal accounts of how people understood and explained the effects of these adjustments on their everyday lives with the popular discourse of stress in the media, I will show how stress became a key means of interpreting the significant social and economic change that was occurring. It also brought about change in both working practices and the ways in which work and well-being were understood by both individual workers and their employers. I will also examine how newspaper reporting of stress suffered by public sector workers, particularly in the NHS and education, revealed the tensions underlying reforms in these areas and will argue that by focusing on worker experience of stress, such reporting effectively drew attention away from the underlying structural changes causing that stress.","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"36 1","pages":"622 - 645"},"PeriodicalIF":0.7,"publicationDate":"2022-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43202112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-19DOI: 10.1080/13619462.2022.2076078
D. Feather
ABSTRACT In July 1969, the Dryden Society, a University of Cambridge performing arts group, arrived in South Africa for a three month tour. Prior to its departure from the United Kingdom, the group’s decision to break the cultural boycott, imposed in response to apartheid, had already caused significant protest. This article discusses the nature of the campaign to stop the tour, as well as highlighting how the British government became involved. The article also demonstrates how, despite having no official support, the tour should be viewed within the prism of British cultural diplomacy, something the British representatives in South Africa were trying to expand at the time. Additionally, the article also draws attention to the ulterior motives of several members of the touring party, who used the tour as cover to clandestinely film the conditions in which South Africa’s black majority lived on behalf of the Pan-Africanist Congress. This was later used to make the critically acclaimed documentary film End of the Dialogue (known in South Africa by its Zulu name of Phela-ndaba) which drew greater international attention to the plight of black South Africans living under apartheid.
{"title":"Creating a ‘deplorable impression’: the Dryden Society’s 1969 tour of South Africa and the making of End of the Dialogue","authors":"D. Feather","doi":"10.1080/13619462.2022.2076078","DOIUrl":"https://doi.org/10.1080/13619462.2022.2076078","url":null,"abstract":"ABSTRACT In July 1969, the Dryden Society, a University of Cambridge performing arts group, arrived in South Africa for a three month tour. Prior to its departure from the United Kingdom, the group’s decision to break the cultural boycott, imposed in response to apartheid, had already caused significant protest. This article discusses the nature of the campaign to stop the tour, as well as highlighting how the British government became involved. The article also demonstrates how, despite having no official support, the tour should be viewed within the prism of British cultural diplomacy, something the British representatives in South Africa were trying to expand at the time. Additionally, the article also draws attention to the ulterior motives of several members of the touring party, who used the tour as cover to clandestinely film the conditions in which South Africa’s black majority lived on behalf of the Pan-Africanist Congress. This was later used to make the critically acclaimed documentary film End of the Dialogue (known in South Africa by its Zulu name of Phela-ndaba) which drew greater international attention to the plight of black South Africans living under apartheid.","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"36 1","pages":"430 - 458"},"PeriodicalIF":0.7,"publicationDate":"2022-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44299724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-28DOI: 10.1080/13619462.2022.2070479
J. Hepworth
ABSTRACT Through four thematic sections, this article explains why, from its inception in 1981, the Revolutionary Communist Party (RCP) espoused ‘unconditional support’ for ‘Irish freedom’, and why this position changed in the 1990s. Illuminating a particularly functional mode of radical solidarity, it argues that British leftists engaged with the Northern Ireland conflict to articulate their revolutionary praxis. Advocating ‘unconditional support’ enabled the RCP to challenge reformism on the British left and nationalism in the labour movement. As the article’s second section demonstrates, such specific left-wing anti-imperialism irked Provisional republican leaders, who demanded a more substantial, inclusive solidarity movement in Britain. The article’s third section elucidates how the Cold War’s denouement from the late 1980s deepened strategic and ideological differences among radicals. Seeking to replicate peace processes in Israel-Palestine and South Africa, Provisional republicans envisaged a negotiated transfer of power in the ‘new world order’. By contrast, lambasting western intervention in the Gulf and the Balkans, RCP theoreticians lamented the ‘moral rearmament of imperialism’. The nascent republican peace strategy of the 1990s conclusively exposed deep-rooted tensions within the RCP’s peculiar solidarity. For disillusioned cadres who had endorsed republicanism only insofar as it threatened the British state, republicanism’s new constitutionalism represented capitulation.
{"title":"‘The moral rearmament of imperialism’: the Revolutionary Communist Party, the Northern Ireland conflict, and the new world order, 1981-1994","authors":"J. Hepworth","doi":"10.1080/13619462.2022.2070479","DOIUrl":"https://doi.org/10.1080/13619462.2022.2070479","url":null,"abstract":"ABSTRACT Through four thematic sections, this article explains why, from its inception in 1981, the Revolutionary Communist Party (RCP) espoused ‘unconditional support’ for ‘Irish freedom’, and why this position changed in the 1990s. Illuminating a particularly functional mode of radical solidarity, it argues that British leftists engaged with the Northern Ireland conflict to articulate their revolutionary praxis. Advocating ‘unconditional support’ enabled the RCP to challenge reformism on the British left and nationalism in the labour movement. As the article’s second section demonstrates, such specific left-wing anti-imperialism irked Provisional republican leaders, who demanded a more substantial, inclusive solidarity movement in Britain. The article’s third section elucidates how the Cold War’s denouement from the late 1980s deepened strategic and ideological differences among radicals. Seeking to replicate peace processes in Israel-Palestine and South Africa, Provisional republicans envisaged a negotiated transfer of power in the ‘new world order’. By contrast, lambasting western intervention in the Gulf and the Balkans, RCP theoreticians lamented the ‘moral rearmament of imperialism’. The nascent republican peace strategy of the 1990s conclusively exposed deep-rooted tensions within the RCP’s peculiar solidarity. For disillusioned cadres who had endorsed republicanism only insofar as it threatened the British state, republicanism’s new constitutionalism represented capitulation.","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"36 1","pages":"591 - 621"},"PeriodicalIF":0.7,"publicationDate":"2022-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48080515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-26DOI: 10.1136/ebnurs-2022-103536
Maxine Radcliffe, Thilo Kroll, Kate Frazer
{"title":"Voice and choice: making a case for tailored smoking cessation programmes to support women experiencing homelessness.","authors":"Maxine Radcliffe, Thilo Kroll, Kate Frazer","doi":"10.1136/ebnurs-2022-103536","DOIUrl":"10.1136/ebnurs-2022-103536","url":null,"abstract":"","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82442627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-26DOI: 10.1080/13619462.2022.2064282
Simon John
ABSTRACT This article investigates the town twinning partnership between Swansea (South Wales) and Mannheim (Baden-Württemberg, Germany) from its inception in the 1950s to the end of the twentieth century. Its findings contribute to scholarship on post-1945 European town twinning, a subject that has not received the attention it deserves, especially from academics working in Britain. The article’s arguments also complicate wider debates surrounding post-war popular relations between Britain and Germany, which have often been cast in existing work as ambivalent or outright hostile. The article adopts a regional approach—emphasising interactions between Wales and Baden-Württemberg rather than at the national level—to offer a new perspective on international relations between Britain and Germany, showing that inhabitants of Swansea and Mannheim forged warm friendships and made efforts to understand each other. The article also highlights the limitations of purely Anglocentric approaches to modern British history, drawing from interactions carried out under the aegis of the Swansea-Mannheim partnership to trace ways in which Welsh identity and the Welsh language shaped external perceptions of the British.
{"title":"Productive European cooperation between Britain and Germany: the Swansea-Mannheim town twinning partnership and exchanges between Wales and Baden-Württemberg, 1950-2000","authors":"Simon John","doi":"10.1080/13619462.2022.2064282","DOIUrl":"https://doi.org/10.1080/13619462.2022.2064282","url":null,"abstract":"ABSTRACT This article investigates the town twinning partnership between Swansea (South Wales) and Mannheim (Baden-Württemberg, Germany) from its inception in the 1950s to the end of the twentieth century. Its findings contribute to scholarship on post-1945 European town twinning, a subject that has not received the attention it deserves, especially from academics working in Britain. The article’s arguments also complicate wider debates surrounding post-war popular relations between Britain and Germany, which have often been cast in existing work as ambivalent or outright hostile. The article adopts a regional approach—emphasising interactions between Wales and Baden-Württemberg rather than at the national level—to offer a new perspective on international relations between Britain and Germany, showing that inhabitants of Swansea and Mannheim forged warm friendships and made efforts to understand each other. The article also highlights the limitations of purely Anglocentric approaches to modern British history, drawing from interactions carried out under the aegis of the Swansea-Mannheim partnership to trace ways in which Welsh identity and the Welsh language shaped external perceptions of the British.","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"36 1","pages":"552 - 590"},"PeriodicalIF":0.7,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41376157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-03DOI: 10.1080/13619462.2022.2051487
M. Worley
ABSTRACT British punk emerged in tandem with the formation of Sex Pistols, a band framed by a style and an aesthetic constructed, in part, by Malcolm McLaren and Vivienne Westwood via their London shop SEX (1974–76). The shop displayed fetishwear and accoutrements designed to fuse youth and sexual subcultures, deploying sex as a cultural weapon to provoke and confront. This article examines the Sadean influences that found expression through punk, suggesting that the Marquis de Sade had a seminal if diffused impact on the punk-informed cultures that evolved through the 1970s into the 1980s. Though often indirect—and bound to broader interpretations of sexual behaviour—the actions, aesthetics and ideas associated with the ‘Divine Marquis’ seemingly tallied with the mood of a country caught in a period of socio-economic and political change.
{"title":"Whip in my valise: British punk and the Marquis de Sade, c. 1975–85","authors":"M. Worley","doi":"10.1080/13619462.2022.2051487","DOIUrl":"https://doi.org/10.1080/13619462.2022.2051487","url":null,"abstract":"ABSTRACT British punk emerged in tandem with the formation of Sex Pistols, a band framed by a style and an aesthetic constructed, in part, by Malcolm McLaren and Vivienne Westwood via their London shop SEX (1974–76). The shop displayed fetishwear and accoutrements designed to fuse youth and sexual subcultures, deploying sex as a cultural weapon to provoke and confront. This article examines the Sadean influences that found expression through punk, suggesting that the Marquis de Sade had a seminal if diffused impact on the punk-informed cultures that evolved through the 1970s into the 1980s. Though often indirect—and bound to broader interpretations of sexual behaviour—the actions, aesthetics and ideas associated with the ‘Divine Marquis’ seemingly tallied with the mood of a country caught in a period of socio-economic and political change.","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"36 1","pages":"277 - 321"},"PeriodicalIF":0.7,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48154739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-03DOI: 10.1080/13619462.2022.2053845
Gil Engelstein
ABSTRACT Spartacus magazine (1969–1972) was one of Britain’s first openly gay periodicals. This essay explores the early career of its publisher, John D. Stamford, to argue for the constitutive role of gay entrepreneurs and transnational erotic commercial networks in articulating queer politics in Britain following the 1967 Sexual Offences Act. An examination of the reception of Stamford’s commercial and political work suggests that gay male consumption preceded political mobilisation rather than followed in its tracks. More so, that consumerism provided a shared vocabulary and an important platform on which a diverse readership coalesced around a set of contradictory political dictums on what constituted ‘proper’ sexual and gender expression.
{"title":"Spartacus magazine and the commercial-political nexus of Gay Liberation","authors":"Gil Engelstein","doi":"10.1080/13619462.2022.2053845","DOIUrl":"https://doi.org/10.1080/13619462.2022.2053845","url":null,"abstract":"ABSTRACT Spartacus magazine (1969–1972) was one of Britain’s first openly gay periodicals. This essay explores the early career of its publisher, John D. Stamford, to argue for the constitutive role of gay entrepreneurs and transnational erotic commercial networks in articulating queer politics in Britain following the 1967 Sexual Offences Act. An examination of the reception of Stamford’s commercial and political work suggests that gay male consumption preceded political mobilisation rather than followed in its tracks. More so, that consumerism provided a shared vocabulary and an important platform on which a diverse readership coalesced around a set of contradictory political dictums on what constituted ‘proper’ sexual and gender expression.","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"36 1","pages":"227 - 252"},"PeriodicalIF":0.7,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43405446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号