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Occupational prevalence with agricultural machinery related injuries among rice farmers in Bang Rakam district, Phitsanulok Province, Thailand 泰国平世洛省Bang Rakam地区稻农中农业机械相关伤害的职业流行率
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.cegh.2025.102285
Chavinthorn Maiyapakdee , Saowanee Norkaew , Nontiya Homkham , Theerayut Baubhom , Katiya Ivanovitch , Teeraphun Kaewdok

Problem considered

Accidents are among the major occupational health hazards, and agricultural machinery is a significant cause of musculoskeletal injuries, including cuts, sprains, and strains, among agriculturists in Thailand. Due to the lack of information in the farmer accident database, this cross-sectional study investigated the prevalence of agricultural machinery-related injuries among rice farmers in Thailand's Bang Rakam District of Phitsanulok Province.

Methods

Data were collected via in-person interviews with 294 rice farmers who used agricultural machinery at any stage of farming activities during the 2023 crop year. The questionnaire consisted of three sections: (1) general information about the farmers, (2) details of their work equipment and practices, and (3) information about injuries sustained during work.

Results

All participants reported experiencing work-related injuries. The machinery most associated with injuries was the walking tractor (41.8 %) followed by the harvesting machine (13.3 %). The most frequently injured body parts were the back and torso (21.8 %), legs, and knees (19.0 %), and hands and fingers (17.3 %). Land preparation activities accounted for the highest proportion of injuries (56.1 %) followed by pesticide application (31.6 %).

Conclusion

This study highlights the prevalence of work-related musculoskeletal injuries among rice farmers, reflecting significant occupational health concerns in Thailand. The findings suggest a need to redesign agricultural machinery, particularly tractors, to enhance safety. Additionally, interventions and safety guidelines should be developed and implemented to prevent occupational accidents in the agricultural sector.
事故是主要的职业健康危害之一,农业机械是泰国农业工人肌肉骨骼损伤的重要原因,包括割伤、扭伤和拉伤。由于农民事故数据库中缺乏信息,本横断面研究调查了泰国彭世洛省Bang Rakam地区稻农中与农业机械相关的伤害发生率。方法通过对294名在2023作物年期间在农业活动的任何阶段使用农业机械的稻农进行面对面访谈,收集数据。问卷包括三个部分:(1)农民的一般情况,(2)他们的工作设备和操作的细节,(3)在工作中受伤的信息。结果所有参与者都报告有工伤经历。与伤害相关最多的机械是手扶拖拉机(41.8%),其次是收获机械(13.3%)。最常受伤的身体部位是背部和躯干(21.8%),腿和膝盖(19.0%),手和手指(17.3%)。整理土地活动造成的伤害比例最高(56.1%),其次是施用农药(31.6%)。结论:本研究强调了水稻农民中与工作相关的肌肉骨骼损伤的患病率,反映了泰国重要的职业健康问题。研究结果表明,需要重新设计农业机械,特别是拖拉机,以提高安全性。此外,应制定和执行干预措施和安全准则,以防止农业部门的职业事故。
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引用次数: 0
Spatiotemporal evolution of dengue hotspots in Kuantan, Malaysia: A decade-long geospatial analysis for adaptive vector control 马来西亚关丹登革热热点的时空演变:自适应媒介控制的十年地理空间分析
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.cegh.2025.102273
Zulkifli Abdul Hadi , Agus Naba , Ahmad Mohiddin Mohd Ngesom , Nazri Che Dom

Problem considered

Dengue continues to pose a major public health burden in Malaysia, particularly in rapidly urbanising districts where shifting land-use patterns influence transmission dynamics. Despite increasing case numbers, evidence on long-term hotspot trajectories at the district scale remains limited. This study examined a decade of dengue transmission in Kuantan District, Malaysia by integrating detailed land-use characteristics with epidemiological and population data to identify persistent, emerging, and expanding hotspots.

Methods

A retrospective spatiotemporal analysis was conducted using laboratory-confirmed dengue cases reported from 2014 to 2023. Case data were geocoded and aggregated at the sub-district level. Residential, commercial, industrial, and green-area land-use layers were standardised and spatially overlaid with dengue incidence rates to quantify their contribution to hotspot formation. Annual incidence rates were calculated to provide a precise measure of disease intensity across sub-districts. A multi-stage geospatial framework comprising Kernel Density Estimation, Space–Time Cube modelling, Mann–Kendall trend analysis, Emerging Hotspot Analysis, and Local Moran's I was applied to evaluate hotspot intensity, persistence, and spatial evolution.

Results

A total of 38,412 dengue cases were documented, with an average annual incidence of 386.5 cases per 100,000 population. Major peaks occurred in 2019 (624.5 per 100,000; 6213 cases) and 2022 (578.2 per 100,000; 5876 cases). Persistent hotspots increased from five in 2016 to nine in 2023, primarily within high-density residential and mixed-commercial zones identified through the land-use overlay analysis. Transitional hotspots frequently emerged in peri-urban areas undergoing rapid land-use change before stabilizing. Local Moran's I showed significant High–High clusters in the urban core (Moran's I = 0.41, p < 0.01).

Conclusion

Dengue transmission in Kuantan has become increasingly entrenched, driven by urban density, mixed land-use development, and peri-urban expansion. Proactive, land-use-informed hotspot surveillance is essential for strengthening targeted dengue control.
登革热在马来西亚继续构成重大公共卫生负担,特别是在快速城市化的地区,不断变化的土地利用模式影响着传播动态。尽管病例数不断增加,但在地区范围内关于长期热点轨迹的证据仍然有限。本研究通过将详细的土地利用特征与流行病学和人口数据相结合,调查了马来西亚关丹地区十年来登革热传播的情况,以确定持续存在的、新出现的和正在扩大的热点。方法对2014 - 2023年登革热病例进行回顾性时空分析。病例数据在分区一级进行地理编码和汇总。将住宅、商业、工业和绿地土地利用层标准化,并在空间上叠加登革热发病率,以量化其对热点形成的贡献。计算了年发病率,以提供对各区疾病强度的精确衡量。采用核密度估计、时空立方体建模、Mann-Kendall趋势分析、新兴热点分析和局部Moran’s I等多阶段地理空间框架对热点强度、持久性和空间演化进行了评价。结果共报告登革热病例38412例,年平均发病率为386.5例/ 10万人。主要高峰发生在2019年(624.5 / 10万,6213例)和2022年(578.2 / 10万,5876例)。持续热点从2016年的5个增加到2023年的9个,主要在高密度住宅和混合商业区内,通过土地利用覆盖分析确定。在土地利用快速变化趋于稳定的城郊地区,频繁出现过渡性热点。当地Moran's I在城市核心显示出显著的High-High集群(Moran's I = 0.41, p < 0.01)。结论受城市密度、混合土地利用开发和城郊扩张等因素的影响,登革热在关丹的传播日益根深蒂固。积极主动、了解土地利用情况的热点监测对于加强有针对性的登革热控制至关重要。
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引用次数: 0
Low dose corticosteroid for a longer duration at an early phase: A potentially optimal dosage regimen for the management of ARDS 早期使用较长时间的低剂量皮质类固醇:治疗ARDS的潜在最佳剂量方案
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.cegh.2025.102282
Muhammed Rashid , Sreedharan Nair , Pooja Gopal Poojari , Vishal Shanbhag , Raviraja V. Acharya , Sohil Khan , Girish Thunga

Problem considered

Disparities exist within both clinical practice and literature regarding the use of corticosteroids in management of acute respiratory distress syndrome (ARDS). Given the absence of definitive evidence from a singular research approach, we adopted a mixed method approach design to address this clinical question.

Methods

We employed a sequential exploratory mixed methods approach. Initially, we conducted a retrospective analysis, which was complemented by a comprehensive literature review to identify the best treatment approaches in literature and practice. Subsequently, a semi-structured qualitative interview was conducted to gain insights into perception and experience of the physicians involved in ARDS management. Finally, a meta-inference was applied to synthesize the evidence to propose a corticosteroid regimen for ARDS, considering the patient etiology, dosage, duration, and timing of administration.

Results

The retrospective evidence (nearly thousand patient data from five years) indicates that, low dose corticosteroid for a longer duration of treatment observed to have a significantly better recovery rate than other strategies. The literature (overview of meta-analyses, clinical guidelines and RCTs), and qualitative (among 9 physicians) evidence strengthened this by supporting the use of low dose corticosteroid (1–2 mg/kg) at the early phase (24–72 h), for a longer duration (minimum 10 days) to have better clinical outcome without safety concerns. Additionally, this provides more insights on ARDS epidemiology, management, efficacy, cost and safety.

Conclusion

Low-dose corticosteroids for a longer duration of treatment administered at an early phase can be considered a potentially optimal corticosteroid regimen for ARDS which needs to be clinically validated in future.
考虑的问题:关于使用皮质类固醇治疗急性呼吸窘迫综合征(ARDS)的临床实践和文献存在差异。鉴于单一研究方法缺乏明确证据,我们采用混合方法方法设计来解决这一临床问题。方法采用顺序探索性混合方法。首先,我们进行了回顾性分析,并辅以全面的文献综述,以确定文献和实践中的最佳治疗方法。随后,进行了半结构化定性访谈,以深入了解参与ARDS管理的医生的看法和经验。最后,综合考虑患者病因、剂量、持续时间和给药时间的综合证据,提出了治疗ARDS的皮质类固醇方案。结果回顾性研究(近五年来近千例患者资料)表明,低剂量皮质类固醇治疗时间较长,其治愈率明显优于其他治疗策略。文献(荟萃分析概述、临床指南和随机对照试验)和定性证据(在9名医生中)通过支持在早期(24-72小时)使用低剂量皮质类固醇(1-2 mg/kg),持续时间较长(至少10天)以获得更好的临床结果而没有安全性问题,加强了这一点。此外,这为ARDS流行病学、管理、疗效、成本和安全性提供了更多的见解。结论早期给予较长时间的低剂量皮质类固醇治疗可能是治疗ARDS的最佳方案,有待于进一步的临床验证。
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引用次数: 0
Burden and determinants of recurrent tuberculosis among patients undergoing treatment: A cross-sectional study in Chennai, a major metropolitan city in South India 在接受治疗的患者中,结核病复发的负担和决定因素:在印度南部大城市金奈进行的一项横断面研究
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.cegh.2025.102271
B.B. Kavyadharshni , D. Senthil Arasi , Chhavi Garg , P. Seenivasan , Edwin Sam Asirvatham

Problem considered

Recurrent Tuberculosis (rTB) refers to the reappearance of TB in a patient previously declared as successfully treated, either cured or having completed treatment. This study aimed to estimate the prevalence of rTB and identify associated risk factors among registered TB patients.

Methods

We conducted a cross-sectional study in Chennai, South India, among TB patients registered across three treatment units under the National TB Elimination Program (NTEP). We included 302 of 337 patients registered between January and June 2019. Socio-demographic information, diagnostic details, and treatment history from the previous TB episode were obtained from TB unit registers. Additionally, we interviewed participants using a structured interview schedule to capture data on current clinical presentation, medical history, risk behaviours and comorbidities.

Results

The prevalence of rTB was 15.6 % (95 % CI:11.7–20.2), with a mean age of 42.3 years (SD: 11.5). Higher rTB rates were observed among males, individuals aged over 35 years, current or former tobacco and alcohol users, pulmonary TB patients, those undergoing or who did not complete previous TB treatment, underweight patients, HIV-positive individuals, and patients with comorbidities such as diabetes and hypertension. Multivariable analysis identified tobacco use, microbiologically confirmed TB, non-completion of previous TB treatment, undernutrition, HIV-positivity, and the presence of comorbidities as significant predictors of rTB.

Conclusion

The study highlights the significant burden of rTB and the complexity of TB recurrence, emphasising the need for comprehensive and continuous care. The findings support the implementation of targeted, context-specific, tailored strategies and interventions that address modifiable risk factors, towards achieving the national goal of eliminating TB by 2025.
考虑到的问题复发性结核病(rTB)是指以前宣布已成功治愈或已完成治疗的患者再次出现结核病。本研究旨在估计在册结核病患者中rTB的患病率,并确定相关的危险因素。方法:我们在印度南部的金奈进行了一项横断面研究,研究对象是根据国家结核病消除计划(NTEP)在三个治疗单位登记的结核病患者。我们纳入了2019年1月至6月期间注册的337名患者中的302名。社会人口学信息、诊断细节和以前结核病发作的治疗史从结核病单位登记中获得。此外,我们使用结构化访谈时间表对参与者进行访谈,以获取有关当前临床表现、病史、风险行为和合并症的数据。结果rTB患病率为15.6% (95% CI:11.7 ~ 20.2),平均年龄42.3岁(SD: 11.5)。男性、年龄在35岁以上的个体、目前或以前的烟酒使用者、肺结核患者、正在接受或未完成以前结核病治疗的患者、体重过轻患者、艾滋病毒阳性个体以及患有糖尿病和高血压等合并症的患者中观察到较高的rTB发病率。多变量分析发现,烟草使用、微生物学证实的结核病、以前未完成结核病治疗、营养不良、艾滋病毒阳性和合并症的存在是rTB的重要预测因素。结论该研究强调了结核病的重大负担和结核病复发的复杂性,强调了全面和持续治疗的必要性。研究结果支持实施有针对性的、针对具体情况的、量身定制的战略和干预措施,以应对可改变的风险因素,从而实现到2025年消除结核病的国家目标。
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引用次数: 0
Sleep knowledge, training, and clinical practices among healthcare professionals in a tertiary hospital in Nepal 尼泊尔一家三级医院保健专业人员的睡眠知识、培训和临床实践
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.cegh.2025.102260
Merina Shrestha , Børge Sivertsen , Daman Raj Poudel , Suman Ranjitkar , Mari Hysing

Problem considered

Adequate sleep knowledge among healthcare professionals is crucial for the assessment and management of pediatric sleep issues. However, there is limited research on sleep literacy among health professionals in low- and middle-income countries (LMICs) such as Nepal. The aim of the study is to assess the level of pediatric sleep knowledge, sleep training, and clinical practices among health care professionals in Nepal.

Methods

A cross-sectional pediatric sleep survey was conducted at a tertiary-level general hospital in Kathmandu, Nepal (N = 83), utilizing the Sleep Knowledge Questionnaire (SKQ) and Pediatric Sleep Survey. Additional questions assessed sleep education and clinical practices related to sleep screening and interventions.

Results

Healthcare professionals reported minimal formal education on sleep, with most receiving fewer than 10 h of training. Only 23.5 % felt adequately prepared for clinical practice. The average correct response rate on the SKQ was 48.5 %, indicating moderate sleep literacy. Sleep screening was inconsistent across age groups and least frequent for infants, with many professionals (49.2 %) citing lack of knowledge as a key barrier. Additionally, 47.7 % assumed parents would report concerns, contributing to low screening rates. While behavioral strategies were preferred over pharmacological treatments, sleep-related interventions were infrequent, with massage therapy (100 %) being the most applied.

Conclusions

This study highlights significant gaps in pediatric sleep knowledge and clinical preparedness among healthcare professionals in Nepal. Increased sleep education and training programs are necessary to enhance the identification and management of pediatric sleep disorders in LMIC settings.
医疗保健专业人员充分的睡眠知识对于儿科睡眠问题的评估和管理至关重要。然而,关于尼泊尔等中低收入国家卫生专业人员睡眠素养的研究有限。该研究的目的是评估尼泊尔卫生保健专业人员的儿科睡眠知识、睡眠培训和临床实践水平。方法采用睡眠知识问卷(SKQ)和《儿童睡眠调查》对尼泊尔加德满都一家三级综合医院的83名儿童进行横断面睡眠调查。其他问题评估了睡眠教育和与睡眠筛查和干预相关的临床实践。结果卫生保健专业人员报告的正规睡眠教育很少,大多数人接受的培训少于10小时。只有23.5%的人认为自己为临床实践做好了充分的准备。SKQ的平均答对率为48.5%,表明睡眠素养中等。不同年龄组的睡眠筛查不一致,婴儿的睡眠筛查频率最低,许多专业人士(49.2%)认为缺乏知识是主要障碍。此外,47.7%的人认为父母会报告他们的担忧,这导致了低筛查率。虽然行为策略比药物治疗更受欢迎,但与睡眠相关的干预很少,按摩疗法(100%)是最常用的。结论:本研究突出了尼泊尔医疗保健专业人员在儿童睡眠知识和临床准备方面的重大差距。增加睡眠教育和培训计划是必要的,以加强在低收入和中等收入国家儿童睡眠障碍的识别和管理。
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引用次数: 0
Machine learning techniques to model child low height-for-age in the Northern Province of Rwanda: The role of climatological and environmental factors and their interactions 卢旺达北部省低身高儿童模型的机器学习技术:气候和环境因素的作用及其相互作用
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1016/j.cegh.2025.102284
A. Ndagijimana , G. Nduwayezu , T. Lind , A. Mansourian

Objective

Childhood stunting is a significant health issue in Rwanda, particularly within the Northern Province. While demographic and socio-economic factors have been more extensively studied, the impact of environmental and climatic factors on stunting prevalence has received less attention. This study aimed to determine if these factors could be used to better predict localized variations in height-for-age z-scores (HAZ).

Study design

A population-based, cross-sectional study.

Methods

Data were collected on child and maternal characteristics, household socioeconomic status, climate, and environmental predictors. An eXtreme Gradient Boosting (XGBoost) algorithm was used, complemented by GeoShapley for spatial analyses, to explain the spatial variability between low height-for-age and its risk factors.

Results

The model performed well, with the coefficient of determination (R2) value of 0.83, the root mean standardized error (RMSE) of 0.13, and the mean absolute error (MAE) of 0.10. Key predictors of HAZ included rainfall, childcare practices, food insecurity, elevation, and soil fertility. Considering the location feature, environmental and climatic factors significantly contributed to the spatial variability in HAZ.

Conclusion

Many environmental, climatological, and socio-economic factors emerge as predictors for HAZ variability. It is essential to consider their complexity for comprehensive interventions targeting childhood stunting in Rwanda and similar settings.
目的儿童发育迟缓是卢旺达,特别是北部省的一个重大健康问题。虽然人口和社会经济因素得到了更广泛的研究,但环境和气候因素对发育迟缓患病率的影响却受到较少的关注。本研究旨在确定这些因素是否可以用来更好地预测身高年龄z分数(HAZ)的局部变化。研究设计:基于人群的横断面研究。方法收集儿童和母亲特征、家庭社会经济状况、气候和环境预测因素的数据。使用极端梯度增强(XGBoost)算法,并辅以GeoShapley进行空间分析,来解释低年龄身高与其风险因素之间的空间变异性。结果该模型运行良好,决定系数(R2)为0.83,均方根标准化误差(RMSE)为0.13,平均绝对误差(MAE)为0.10。HAZ的主要预测因子包括降雨、儿童保育实践、粮食不安全、海拔和土壤肥力。考虑到区位特征,环境和气候因素对HAZ的空间变异有显著影响。结论:许多环境、气候和社会经济因素可以作为HAZ变异性的预测因子。对于针对卢旺达和类似情况下儿童发育迟缓的综合干预措施,必须考虑到其复杂性。
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引用次数: 0
Correlation between obesity and urinary malondialdehyde levels in a rural Southern Thai population: A cross-sectional study 泰国南部农村人口肥胖与尿丙二醛水平的相关性:一项横断面研究
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-24 DOI: 10.1016/j.cegh.2025.102258
Thitiworn Choosong , Tulyawat Nuantong , Angsutorn Udompolchaicharoen , Chanunthon Wonglaw , Natthanon Thongnoul , Napatsavan Kongkleang , Pariyakorn Phonui , Pannawit Chumchue , Pornlapat Rattanakhot , Awika Kaeotawee , Thammasin Ingviya

Problem considered

Rapidly growing economies and the planned establishment of multiple biomass power plants in rural areas may influence urinary malondialdehyde levels: an indicator of oxidative stress. Therefore, this study assessed baseline urinary malondialdehyde levels, and the prevalence of obesity in a rural population.

Methods

An analytical cross-sectional study was conducted in two cities within Songkhla Province, designated as future special economic zones; from May 2019 until December 2021. Participants were categorized into obesity and non-obesity groups. A 24-h urine sample was collected from each participant to measure urinary malondialdehyde levels using high-performance liquid chromatography. Data were analysed using R programming.

Results

A total of 524 datasets were obtained. The median urinary malondialdehyde level was 3.114 μg/mL. Urinary malondialdehyde levels were higher in smokers (3.963 ± 2.140 μg/mL) and passive smokers (3.750 ± 2.111 μg/mL) than in non-smokers (3.523 ± 2.120 μg/mL) and non-passive smokers (3.405 ± 1.961 μg/mL). However, the though differences were not significant. The prevalence of obesity was 44.27 %, with the majority of those affected being women (68.96 %). Urinary malondialdehyde levels were significantly higher in the obesity group (3.796 ± 2.075 μg/mL) than in the non-obesity group (3.462 ± 2.032 μg/mL). Obesity was associated with higher urinary malondialdehyde levels, while female participants and dyslipidemia patients had significantly lower levels.

Conclusion

In the rural population, urinary malondialdehyde levels were low. Obesity, particularly among women, was prevalent. Smoke exposure, obesity and dyslipidemia warrant attention. Therefore, future public health strategies should consider holistic prevention programs, integrating pollution exposure and obesity concerns.
快速增长的经济和计划在农村地区建立多个生物质发电厂可能会影响尿丙二醛水平:氧化应激的一个指标。因此,本研究评估了基线尿丙二醛水平和农村人口肥胖的患病率。方法采用横断面分析方法,对宋卡省内两个被指定为未来经济特区的城市进行研究;从2019年5月至2021年12月。参与者被分为肥胖组和非肥胖组。从每个参与者收集24小时尿液样本,使用高效液相色谱法测量尿丙二醛水平。数据分析使用R编程。结果共获得524组数据集。尿丙二醛中位数为3.114 μg/mL。吸烟者(3.963±2.140 μg/mL)和被动吸烟者(3.750±2.111 μg/mL)尿丙二醛水平高于非吸烟者(3.523±2.120 μg/mL)和非被动吸烟者(3.405±1.961 μg/mL)。然而,尽管差异不显著。肥胖患病率为44.27%,其中以女性居多(68.96%)。肥胖组尿丙二醛水平(3.796±2.075 μg/mL)显著高于非肥胖组(3.462±2.032 μg/mL)。肥胖与较高的尿丙二醛水平有关,而女性参与者和血脂异常患者的水平明显较低。结论农村人群尿丙二醛水平较低。肥胖,尤其是女性,非常普遍。吸烟、肥胖和血脂异常值得注意。因此,未来的公共卫生策略应考虑整体预防方案,将污染暴露和肥胖问题结合起来。
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引用次数: 0
Role of two-day injectable dexamethasone therapy in the resolution of uncomplicated parapneumonic effusion: A single-blinded randomized trial 两天注射地塞米松治疗在解决无并发症肺旁积液中的作用:一项单盲随机试验
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-22 DOI: 10.1016/j.cegh.2025.102266
Anshika Mishra , Shally Awasthi

Objective

To assess the effect of two days of intravenous dexamethasone therapy on the resolution of uncomplicated parapneumonic effusion in hospitalized children aged 1 month to 14 years, as measured by standardized pleural fluid volume estimation on bedside ultrasonography (posterior axillary and interscapular views, using Eibenberger's formula) on days 34 of admission.

Methods

This single-center, randomized, single-blind, parallel-group clinical trial included 62 children diagnosed with community-acquired pneumonia (CAP) and pleural effusion. Participants were randomized into two groups: the intervention group received intravenous dexamethasone (0.25 mg/kg/dose) four times daily for two days along with antibiotics and usual care, while the control group received only antibiotics and usual care. The primary outcome was the resolution of pleural effusion based on ultrasonographic volume. Secondary outcomes included changes in inflammatory markers, hospital length of stay, need for pleural intervention, and adverse events.

Results

All 62 patients (mean age 2 years; 61.3 % male) completed the study. In the intervention group, the mean pleural fluid volume decreased significantly from 13.97 ± 6.61 ml on admission to 3.22 ± 3.99 ml by day 4. In contrast, the control group showed an increase from 15 ± 7.53 ml to 17.07 ± 12.36 ml (p < 0.001). The intervention group also showed a significant reduction in C-reactive protein (CRP) and total leukocyte count compared to controls (p < 0.001). Mean hospital stay was significantly shorter in the dexamethasone group (5.8 ± 1.2 vs 7.3 ± 1.6 days, p = 0.01). None of the patients required pleural drainage. Multivariate linear regression identified dexamethasone intervention as the only significant predictor of effusion resolution (p = 0.0001). No significant differences in complications or adverse events were observed between groups.

Conclusion

Short-course intravenous dexamethasone therapy significantly accelerates the resolution of uncomplicated parapneumonic effusion in children without increasing adverse effects. It also reduces hospital stay without increasing the need for drainage and may serve as a safe and effective adjunct to standard antibiotic therapy in pediatric patients with CAP-associated effusion.
目的评价2天静脉地塞米松治疗对1个月至14岁住院儿童无并发症肺旁积液的解决效果,入院第3-4天床边超声检查(腋窝后和肩胛间,采用Eibenberger公式)胸膜积液量的标准化评估。方法本研究为单中心、随机、单盲、平行组临床试验,纳入62例确诊为社区获得性肺炎(CAP)和胸腔积液的儿童。随机分为两组:干预组给予静脉注射地塞米松(0.25 mg/kg/剂),每日4次,连续2天,同时给予抗生素和常规护理;对照组只给予抗生素和常规护理。主要结果是基于超声容积的胸腔积液的溶解。次要结局包括炎症标志物的变化、住院时间、胸膜干预的需要和不良事件。结果62例患者全部完成研究,平均年龄2岁,男性61.3%。干预组平均胸腔积液量由入院时的13.97±6.61 ml显著下降至入院第4天的3.22±3.99 ml。对照组从15±7.53 ml增加到17.07±12.36 ml (p < 0.001)。与对照组相比,干预组的c反应蛋白(CRP)和总白细胞计数也显著降低(p < 0.001)。地塞米松组平均住院时间明显缩短(5.8±1.2天vs 7.3±1.6天,p = 0.01)。没有病人需要胸腔引流。多元线性回归发现地塞米松干预是积液缓解的唯一显著预测因子(p = 0.0001)。两组间并发症及不良事件发生率无显著差异。结论短期静脉地塞米松治疗可显著促进患儿无并发症的肺旁积液的消退,且无不良反应增加。它还可以减少住院时间,而不增加引流的需要,并且可以作为cap相关积液儿科患者标准抗生素治疗的安全有效的辅助治疗。
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引用次数: 0
A qualitative assessment of Community and stakeholders' perception towards Malaria elimination in Gujarat focusing behavior of community 社区和利益相关者对古吉拉特邦消除疟疾认知的定性评估,重点关注社区行为
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-20 DOI: 10.1016/j.cegh.2025.102267
Niraj Pandit , Arpita Patel , Manju Rahi , Sachin Sharma , Nirmal Jyoti Jyotsana , Yagna Pandit

Problem considered

In the last couple of years, the incidence and prevalence of malaria in Gujarat have declined as compared to Indian data. India's goal is to end malaria by the year 2030, for which community behavior is vital apart from other logistics and treatment management. This qualitative study conducted with aim to determine the perceptions of community towards malaria.

Methods

The qualitative assessment was conducted in the two districts of Gujarat during September 2022 and November 2022. Data were collected through Focus Group discussions (FGDs), in-depth interviews (IDIs), and key informant interviews (KIIs) with the help of a qualitative guide. Data were analyzed through thematic framework.

Results

64 interviews consisting of 12 FGDs were carried out, combining the use of FGDs, KIIs, and IDIs. Review of community perception regarding malaria elimination was conducted and it was observed that they had sufficient knowledge regarding symptoms and diagnosis and their practices of the same were seen. Supportive presence of community in prevention and control measures to the government action was observed. The key gaps were seen on sustained social and behaviour change communication, human resources management, malaria among migratory population and poor interdepartmental coordination.

Conclusion

The stakeholders in this study expressed their optimism regarding the progress towards eliminating malaria in Gujarat, but at a slower pace. The areas which required to improve like diagnosis coverage among migratory population and compliance with treatment regimens. The identified gaps can be targeted like sustainable funding for BCC, manpower management and malaria in migratory population.
在过去几年中,与印度的数据相比,古吉拉特邦的疟疾发病率和流行率有所下降。印度的目标是到2030年消灭疟疾,为此,除了其他后勤和治疗管理之外,社区行为至关重要。这项定性研究的目的是确定社区对疟疾的看法。方法于2022年9月和2022年11月在古吉拉特邦两个区进行定性评价。在定性指南的帮助下,通过焦点小组讨论(fgd)、深度访谈(IDIs)和关键信息提供者访谈(KIIs)收集数据。通过专题框架对数据进行分析。结果共进行了64次访谈,包括12个fdd,并结合了fdd、kii和idi的使用。对社区对消除疟疾的看法进行了审查,观察到他们对症状和诊断有足够的了解,并观察到他们的做法。观察到社区在预防和控制措施方面对政府行动的支持。主要的差距体现在持续的社会和行为改变沟通、人力资源管理、移徙人口中的疟疾和部门间协调不力。本研究的利益相关者对古吉拉特邦消除疟疾的进展表示乐观,但速度较慢。需要改进的领域包括移徙人口的诊断覆盖率和治疗方案的遵守情况。可以针对已确定的差距,例如为BCC提供可持续资金、人力管理和移徙人口的疟疾。
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引用次数: 0
Depression and influencing factors among pregnant women living in central Viet Nam: A mixed-methods study 越南中部孕妇抑郁及其影响因素:一项混合方法研究
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-19 DOI: 10.1016/j.cegh.2025.102268
Minh Ho , Tung Viet Le , Ly Thi-Ly Tran , Huong Thanh Nguyen

Problem considered

Antenatal depression can create social and economic pressures for families and communities. Pregnant women with antenatal depression may struggle to maintain employment, manage household responsibilities, and provide a stable environment for the fetus. Assessing the prevalence of antenatal depression and its influencing factors provides necessary information to develop support programs for pregnant women and their families.

Methods

A mixed-method study design was employed. Quantitative information assessed signs of depression using the Edinburgh Postnatal Depression scale among 312 pregnant women residing in Da Nang City. Qualitative information was gathered through in-depth interviews with 8 participants, including representatives of healthcare managers and staff, and focus group discussions with pregnant women exhibiting and not exhibiting signs of depression. Quantitative data were analysed using descriptive statistics and univariate logistic regression, while qualitative data were recorded, transcribed, and thematically analysed.

Results

The study found 28.2 % prevalence of antenatal depression. Qualitative analysis revealed positive influencing factors including: marital status (married/living with partner), planned pregnancy, support from husband's family, good relationship with husband, and having social support; Negative influencing factors included: advanced maternal age, low educational attainment, previous pregnancy complications, fetal abnormalities, having two or more children, poor relationship with mother-in-law, preference for male offspring within the family, experiencing mental and physical violence from the husband, and the support from service providers is inadequate.

Conclusions

Depression symptoms are prevalent among pregnant women, so it's important for healthcare professionals to understand the risk factors for depression in pregnant women.
产前抑郁症会给家庭和社区带来社会和经济压力。患有产前抑郁症的孕妇可能难以维持工作,承担家庭责任,并为胎儿提供稳定的环境。评估产前抑郁症的患病率及其影响因素为制定孕妇及其家庭的支持计划提供了必要的信息。方法采用混合方法设计。定量信息采用爱丁堡产后抑郁量表评估了居住在岘港市的312名孕妇的抑郁症状。通过对8名参与者(包括医疗保健管理人员和工作人员的代表)的深入访谈,以及与表现出和没有表现出抑郁迹象的孕妇进行焦点小组讨论,收集了定性信息。定量数据采用描述性统计和单变量逻辑回归进行分析,而定性数据则进行记录、转录和主题分析。结果产前抑郁患病率为28.2%。定性分析显示,积极影响因素包括:婚姻状况(已婚/同居)、有计划怀孕、丈夫家庭支持、与丈夫关系良好、有社会支持;负面影响因素包括:产妇高龄、受教育程度低、以前的妊娠并发症、胎儿畸形、有两个或两个以上子女、与婆婆关系差、家庭中偏爱男性后代、遭受丈夫的精神和身体暴力以及服务提供者的支持不足。结论孕妇抑郁症状普遍存在,因此了解孕妇抑郁的危险因素对医护人员来说非常重要。
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引用次数: 0
期刊
Clinical Epidemiology and Global Health
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