首页 > 最新文献

Clinical Epidemiology and Global Health最新文献

英文 中文
Relationship between postpartum depression and exclusive breastfeeding practices among urban mothers, Bhubaneswar, Odisha 奥里萨邦布巴内斯瓦尔城市母亲产后抑郁症与纯母乳喂养的关系
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-01 Epub Date: 2026-01-14 DOI: 10.1016/j.cegh.2025.102259
Deepanjali Behera , Manasmruti Sahu , Manas Ranjan Behera , Magnus Micchael Sichalwe , Manatee Jitanan , Janmejaya Samal , Ranjit Kumar Dehury , Damodar Jena

Problem considered

Postpartum depression (PPD) involves persistent sadness, fatigue, and bonding difficulties, while exclusive breastfeeding (EBF) means feeding infants only breast milk for six months. Both are vital for maternal and child health, yet their relationship is understudied. This study examined the prevalence of PPD among mothers in urban Bhubaneswar, Odisha, and its association with EBF.

Methods

An analytical cross-sectional study was conducted among 107 postpartum mothers in urban Bhubaneswar from February to April 2024. A pre-designed questionnaire captured socio-demographic characteristics and breastfeeding practices. Data were analyzed using SPSS version 27. Univariate analysis described variables, bivariate analysis assessed associations between categorical variables, and multivariate analysis identified predictors of postpartum depression at a significance level of p ≤ 0.05.

Results

Among the mothers surveyed, 12.1 % reported postpartum depression, while 94.4 % practiced exclusive breastfeeding. Cesarean delivery was associated with over fourfold higher odds of depression compared to vaginal delivery (AOR = 4.41, 95 % CI: 2.19–16.27, p = 0.001). Mothers who planned to breastfeed for ≤12 months (AOR = 5.34, 95 % CI: 1.07–26.61, p = 0.04) and those intending 12–24 months (AOR = 10.28, 95 % CI: 1.14–93.14, p = 0.03) also had significantly greater odds of postpartum depression compared to those planning >24 months.

Conclusion

Postpartum depression is linked to normal vaginal delivery and shorter planned breastfeeding durations. Early screening and breastfeeding support are essential to improve maternal mental health and infant care.
产后抑郁症(PPD)包括持续的悲伤、疲劳和联系困难,而纯母乳喂养(EBF)意味着只给婴儿喂母乳六个月。两者对孕产妇和儿童健康都至关重要,但它们之间的关系尚未得到充分研究。本研究调查了奥里萨邦布巴内斯瓦尔城市母亲PPD的患病率及其与EBF的关系。方法对2024年2月至4月布巴内斯瓦尔市107名产后母亲进行分析性横断面研究。预先设计的调查问卷包含了社会人口特征和母乳喂养做法。数据分析采用SPSS 27版。单因素分析描述变量,双因素分析评估分类变量之间的相关性,多因素分析确定产后抑郁的预测因素,p≤0.05。结果12.1%的母亲报告产后抑郁,94.4%的母亲实行纯母乳喂养。与阴道分娩相比,剖宫产患抑郁症的几率高出4倍以上(AOR = 4.41, 95% CI: 2.19-16.27, p = 0.001)。计划母乳喂养≤12个月的母亲(AOR = 5.34, 95% CI: 1.07-26.61, p = 0.04)和计划母乳喂养12 - 24个月的母亲(AOR = 10.28, 95% CI: 1.14-93.14, p = 0.03)患产后抑郁症的几率也明显高于计划母乳喂养24个月的母亲。结论产后抑郁与正常阴道分娩和较短的计划母乳喂养时间有关。早期筛查和母乳喂养支持对于改善孕产妇心理健康和婴儿护理至关重要。
{"title":"Relationship between postpartum depression and exclusive breastfeeding practices among urban mothers, Bhubaneswar, Odisha","authors":"Deepanjali Behera ,&nbsp;Manasmruti Sahu ,&nbsp;Manas Ranjan Behera ,&nbsp;Magnus Micchael Sichalwe ,&nbsp;Manatee Jitanan ,&nbsp;Janmejaya Samal ,&nbsp;Ranjit Kumar Dehury ,&nbsp;Damodar Jena","doi":"10.1016/j.cegh.2025.102259","DOIUrl":"10.1016/j.cegh.2025.102259","url":null,"abstract":"<div><h3>Problem considered</h3><div>Postpartum depression (PPD) involves persistent sadness, fatigue, and bonding difficulties, while exclusive breastfeeding (EBF) means feeding infants only breast milk for six months. Both are vital for maternal and child health, yet their relationship is understudied. This study examined the prevalence of PPD among mothers in urban Bhubaneswar, Odisha, and its association with EBF.</div></div><div><h3>Methods</h3><div>An analytical cross-sectional study was conducted among 107 postpartum mothers in urban Bhubaneswar from February to April 2024. A pre-designed questionnaire captured socio-demographic characteristics and breastfeeding practices. Data were analyzed using SPSS version 27. Univariate analysis described variables, bivariate analysis assessed associations between categorical variables, and multivariate analysis identified predictors of postpartum depression at a significance level of p ≤ 0.05.</div></div><div><h3>Results</h3><div>Among the mothers surveyed, 12.1 % reported postpartum depression, while 94.4 % practiced exclusive breastfeeding. Cesarean delivery was associated with over fourfold higher odds of depression compared to vaginal delivery (AOR = 4.41, 95 % CI: 2.19–16.27, p = 0.001). Mothers who planned to breastfeed for ≤12 months (AOR = 5.34, 95 % CI: 1.07–26.61, p = 0.04) and those intending 12–24 months (AOR = 10.28, 95 % CI: 1.14–93.14, p = 0.03) also had significantly greater odds of postpartum depression compared to those planning &gt;24 months.</div></div><div><h3>Conclusion</h3><div>Postpartum depression is linked to normal vaginal delivery and shorter planned breastfeeding durations. Early screening and breastfeeding support are essential to improve maternal mental health and infant care.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"38 ","pages":"Article 102259"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors influencing the childbirth experience of mothers underwent labour induction in Northwest Ethiopia: A Mixed-methods Study 影响埃塞俄比亚西北部引产母亲分娩经验的因素:一项混合方法研究
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-01 Epub Date: 2026-01-19 DOI: 10.1016/j.cegh.2026.102296
Srawork Tesfaye , Endeshaw Admasu , Eden Bishaw Taye , Mengstu Melkamu Asaye

Background

Induction of labor is an obstetric intervention. It can be a significant biomedical and psychosocial event, resulting in a range of positive or negative childbirth experiences. Gaining in-depth knowledge in these areas may help improve the quality of care and the utilization of maternity services. However, in Ethiopia, no studies have been conducted to date.

Objective

To assess mothers’ childbirth experiences and influencing factors among those who underwent induction of labor.

Methods

A facility-based mixed-methods study was conducted from 5 May to August 20, 2025 among 422 mothers. Data were collected using contextualized tools. Audio transcription and translation were performed for the qualitative data. Logistic regression analysis was used, with a P-value of less than 0.05 considered significant. Thematic analysis was applied to the qualitative data.

Results

The proportion of positive childbirth experiences was 236 (55.9 %) (95 % CI: 51.2–60.7). Being multiparous (AOR = 8.63, 95 % CI: 5.21–14.27), having a vaginal delivery (AOR = 2.11, 95 % CI: 1.31–3.41), age under 20 (AOR = 4.65, 95 % CI: 1.53–14.13), and age 21–30 (AOR = 2.35, 95 % CI: 1.22–4.51) were associated factors. The identified facilitators were trust building at admission, clear communication, and labour pain coping strategies. In contrast, feeling disturbed and lack of involvement were barriers that negatively affected mothers' childbirth experiences.

Conclusion

The proportion of positive childbirth experiences was moderate. Building trust, clear communication with healthcare providers, and strategies to manage labour pain were facilitators. Emotional disturbances and lack of involvement were barriers to a positive childbirth experience.
背景引产是一种产科干预措施。它可能是一个重大的生物医学和社会心理事件,导致一系列积极或消极的分娩经历。在这些领域获得深入的知识可能有助于提高护理质量和产妇服务的利用。然而,在埃塞俄比亚,迄今尚未进行任何研究。目的了解引产产妇分娩经历及其影响因素。方法于2025年5月5日至8月20日对422名产妇进行综合调查。使用情境化工具收集数据。对定性数据进行音频转录和翻译。采用Logistic回归分析,p值小于0.05为显著性。对定性数据进行专题分析。结果阳性分娩比例为236例(55.9%)(95% CI: 51.2 ~ 60.7)。多产(AOR = 8.63, 95% CI: 5.21 ~ 14.27)、阴道分娩(AOR = 2.11, 95% CI: 1.31 ~ 3.41)、年龄在20岁以下(AOR = 4.65, 95% CI: 1.53 ~ 14.13)、年龄在21 ~ 30岁(AOR = 2.35, 95% CI: 1.22 ~ 4.51)为相关因素。确定的促进因素是入院时建立信任,明确沟通和分娩疼痛应对策略。相比之下,感到不安和缺乏参与是对母亲分娩经历产生负面影响的障碍。结论阳性分娩经历比例适中。建立信任、与医疗保健提供者明确沟通以及管理分娩疼痛的策略是促进因素。情绪紊乱和缺乏参与是积极分娩经历的障碍。
{"title":"Factors influencing the childbirth experience of mothers underwent labour induction in Northwest Ethiopia: A Mixed-methods Study","authors":"Srawork Tesfaye ,&nbsp;Endeshaw Admasu ,&nbsp;Eden Bishaw Taye ,&nbsp;Mengstu Melkamu Asaye","doi":"10.1016/j.cegh.2026.102296","DOIUrl":"10.1016/j.cegh.2026.102296","url":null,"abstract":"<div><h3>Background</h3><div>Induction of labor is an obstetric intervention. It can be a significant biomedical and psychosocial event, resulting in a range of positive or negative childbirth experiences. Gaining in-depth knowledge in these areas may help improve the quality of care and the utilization of maternity services. However, in Ethiopia, no studies have been conducted to date.</div></div><div><h3>Objective</h3><div>To assess mothers’ childbirth experiences and influencing factors among those who underwent induction of labor.</div></div><div><h3>Methods</h3><div>A facility-based mixed-methods study was conducted from 5 May to August 20, 2025 among 422 mothers. Data were collected using contextualized tools. Audio transcription and translation were performed for the qualitative data. Logistic regression analysis was used, with a P-value of less than 0.05 considered significant. Thematic analysis was applied to the qualitative data.</div></div><div><h3>Results</h3><div>The proportion of positive childbirth experiences was 236 (55.9 %) (95 % CI: 51.2–60.7). Being multiparous (AOR = 8.63, 95 % CI: 5.21–14.27), having a vaginal delivery (AOR = 2.11, 95 % CI: 1.31–3.41), age under 20 (AOR = 4.65, 95 % CI: 1.53–14.13), and age 21–30 (AOR = 2.35, 95 % CI: 1.22–4.51) were associated factors. The identified facilitators were trust building at admission, clear communication, and labour pain coping strategies. In contrast, feeling disturbed and lack of involvement were barriers that negatively affected mothers' childbirth experiences.</div></div><div><h3>Conclusion</h3><div>The proportion of positive childbirth experiences was moderate. Building trust, clear communication with healthcare providers, and strategies to manage labour pain were facilitators. Emotional disturbances and lack of involvement were barriers to a positive childbirth experience.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"38 ","pages":"Article 102296"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and correlates of metabolic syndrome in type 2 diabetes patients: A cross sectional study at the provincial diabetes center in Meknes, Morocco 2型糖尿病患者代谢综合征的患病率及其相关因素:摩洛哥梅克内斯省糖尿病中心的横断面研究
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-01 Epub Date: 2026-02-12 DOI: 10.1016/j.cegh.2026.102320
Daoud Daoudi , Nouriya Elghoulam , Nadia El Mahri , Aichetou Bouh , Youssef Aboussalah , Abdellah Zinedine , Saber Boutayeb , Souad Benaich , Slimane Mehdad

Problem considered

Metabolic syndrome (MetS) is a key contributor to cardiovascular complications among adults with type 2 diabetes (T2D). However, information regarding the prevalence and factors related to MetS among adults with T2D is scarce in Morocco. The aim of this study was to estimate the prevalence of MetS and identify the risk and protective factors among adults with T2D in Meknes, Morocco.

Methods

A cross-sectional study was conducted with 425 adult patients with T2D attending the provincial diabetes center in Meknes, Morocco. Data were collected using structured questionnaires and medical records. MetS was defined using the 2009 harmonized IDF/AHA/NHLBI criteria.

Results

Overall, 72.9% of participants met the criteria for MetS, with a higher prevalence in women (81.2%) than men (58.4%; p < 0.001). Overweight and obesity were the strongest risk factors (AOR = 14.25; 95% CI: 6.77–29.96; p < 0.001), followed by insufficient sleep (AOR = 2.44; p = 0.004) and a family history of cardiovascular disease (AOR = 2.64; p = 0.004). Protective factors included male sex (AOR = 0.13; p < 0.001), rural residence (AOR = 0.51; p = 0.029), higher education (AOR = 0.20; p = 0.029), adherence to the Mediterranean diet (AOR = 0.23; p = 0.003), and moderate to high physical activity (AOR = 0.23–0.31; p ≤ 0.022).

Conclusion

MetS is very common among adults with T2D in Meknes, with most risk factors being modifiable. There is a need for targeted interventions, especially among women, urban dwellers, and those with lower education, to reduce the burden of MetS.
代谢综合征(MetS)是成人2型糖尿病(T2D)心血管并发症的关键因素。然而,在摩洛哥,关于成年T2D患者中met的患病率和相关因素的信息很少。本研究的目的是估计MetS的患病率,并确定摩洛哥梅克内斯成人T2D患者的风险和保护因素。方法对在摩洛哥梅克内斯省糖尿病中心就诊的425例成年T2D患者进行横断面研究。使用结构化问卷和医疗记录收集数据。MetS的定义采用2009年统一的IDF/AHA/NHLBI标准。结果总体而言,72.9%的参与者符合MetS标准,女性患病率(81.2%)高于男性(58.4%;p < 0.001)。超重和肥胖是最强的危险因素(AOR = 14.25; 95% CI: 6.77-29.96; p < 0.001),其次是睡眠不足(AOR = 2.44; p = 0.004)和心血管疾病家族史(AOR = 2.64; p = 0.004)。保护因素包括男性(AOR = 0.13; p < 0.001)、农村居住(AOR = 0.51; p = 0.029)、高等教育(AOR = 0.20; p = 0.029)、坚持地中海饮食(AOR = 0.23; p = 0.003)、中高强度体育活动(AOR = 0.23 - 0.31; p≤0.022)。结论met在梅克纳斯成人T2D患者中非常常见,且大多数危险因素可改变。有必要采取有针对性的干预措施,特别是在妇女、城市居民和受教育程度较低的人群中,以减轻MetS的负担。
{"title":"Prevalence and correlates of metabolic syndrome in type 2 diabetes patients: A cross sectional study at the provincial diabetes center in Meknes, Morocco","authors":"Daoud Daoudi ,&nbsp;Nouriya Elghoulam ,&nbsp;Nadia El Mahri ,&nbsp;Aichetou Bouh ,&nbsp;Youssef Aboussalah ,&nbsp;Abdellah Zinedine ,&nbsp;Saber Boutayeb ,&nbsp;Souad Benaich ,&nbsp;Slimane Mehdad","doi":"10.1016/j.cegh.2026.102320","DOIUrl":"10.1016/j.cegh.2026.102320","url":null,"abstract":"<div><h3>Problem considered</h3><div>Metabolic syndrome (MetS) is a key contributor to cardiovascular complications among adults with type 2 diabetes (T2D). However, information regarding the prevalence and factors related to MetS among adults with T2D is scarce in Morocco. The aim of this study was to estimate the prevalence of MetS and identify the risk and protective factors among adults with T2D in Meknes, Morocco.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted with 425 adult patients with T2D attending the provincial diabetes center in Meknes, Morocco. Data were collected using structured questionnaires and medical records. MetS was defined using the 2009 harmonized IDF/AHA/NHLBI criteria.</div></div><div><h3>Results</h3><div>Overall, 72.9% of participants met the criteria for MetS, with a higher prevalence in women (81.2%) than men (58.4%; p &lt; 0.001). Overweight and obesity were the strongest risk factors (AOR = 14.25; 95% CI: 6.77–29.96; p &lt; 0.001), followed by insufficient sleep (AOR = 2.44; p = 0.004) and a family history of cardiovascular disease (AOR = 2.64; p = 0.004). Protective factors included male sex (AOR = 0.13; p &lt; 0.001), rural residence (AOR = 0.51; p = 0.029), higher education (AOR = 0.20; p = 0.029), adherence to the Mediterranean diet (AOR = 0.23; p = 0.003), and moderate to high physical activity (AOR = 0.23–0.31; p ≤ 0.022).</div></div><div><h3>Conclusion</h3><div>MetS is very common among adults with T2D in Meknes, with most risk factors being modifiable. There is a need for targeted interventions, especially among women, urban dwellers, and those with lower education, to reduce the burden of MetS.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"38 ","pages":"Article 102320"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
May Measurement Month (MMM) program 2021–2024: Results of a community screening program in can Tho city, Vietnam 五月测量月(MMM)计划2021-2024:越南芹苴市社区筛查计划的结果
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-01 Epub Date: 2026-01-22 DOI: 10.1016/j.cegh.2026.102302
Son Kim Tran , Cuong Tan Vo , Phuong Minh Nguyen , Dung The Bui , Chau Minh Tran , Toan Hoang Ngo , Minh Van Huynh

Problem considered

Hypertension (HTN) remains one of the most pressing global health challenges, straining healthcare systems. The May Measurement Month (MMM) campaign aims to raise blood pressure (BP) awareness and address screening gaps. This study screened volunteers aged ≥18 for HTN and cardiovascular risk factors to assess prevalence, awareness, and management effectiveness.

Methods

This study employed a cross-sectional, opportunistic survey design. Data were collected from adults aged ≥18 years between 2021 and 2024 as part of the MMM initiative.

Results

Among 4105 participants (mean age 53.0 ± 15.3 years), 37.2 % had HTN. Of untreated individuals, 72.5 % were hypertensive, while 53.4 % of treated cases remained uncontrolled (BP ≥ 140/90 mmHg). HTN prevalence rose from 28.9 % (2021) to 47.8 % (2024), with BP control improving to 46.5 % (p < 0.001). HTN was highest in ≥60 years (46.8 %) and lowest in <45 years (15.4 %), while BP control remained stable (33.5 %–35.1 %). Males had higher HTN prevalence, though BP control differences were not significant (p > 0.05). In univariate analyses, HTN was associated with smoking, alcohol use, overweight–obesity, pregnancy, and cardiovascular comorbidities. In the multivariate model from MMM 2021–2024, independent contributors to HTN included older age, heart attack, stroke, diabetes, and physical inactivity, whereas smoking and male sex did not retain statistical significance.

Conclusion

The MMM 2021–2024 campaign, conducted during COVID-19, highlighted the need for BP screening in Vietnam. Despite pandemic challenges, undiagnosed and uncontrolled HTN remain major concerns. Standardized screening like MMM remains crucial for detecting high BP and improving HTN management.
高血压(HTN)仍然是最紧迫的全球卫生挑战之一,给卫生保健系统带来了压力。五月测量月(MMM)活动旨在提高血压(BP)的意识并解决筛查差距。本研究筛选年龄≥18岁的志愿者进行HTN和心血管危险因素的筛查,以评估患病率、意识和管理有效性。方法本研究采用横断面、机会性调查设计。作为MMM计划的一部分,从2021年至2024年期间年龄≥18岁的成年人中收集数据。结果4105名参与者(平均年龄53.0±15.3岁)中,37.2%患有HTN。在未治疗的个体中,72.5%为高血压,而53.4%的治疗病例仍未控制(血压≥140/90 mmHg)。HTN患病率从28.9%(2021年)上升到47.8%(2024年),血压控制率提高到46.5% (p < 0.001)。≥60岁时HTN最高(46.8%),≥45岁时最低(15.4%),血压控制保持稳定(33.5% ~ 35.1%)。男性HTN患病率较高,但血压控制差异无统计学意义(p > 0.05)。在单变量分析中,HTN与吸烟、饮酒、超重肥胖、怀孕和心血管合并症有关。在MMM 2021-2024多元模型中,HTN的独立影响因素包括年龄较大、心脏病发作、中风、糖尿病和缺乏运动,而吸烟和男性性别没有统计学意义。结论在2019冠状病毒病期间开展的MMM 2021-2024运动强调了在越南进行BP筛查的必要性。尽管面临大流行的挑战,但未确诊和不受控制的HTN仍然是主要问题。像MMM这样的标准化筛查对于发现高血压和改善HTN管理仍然至关重要。
{"title":"May Measurement Month (MMM) program 2021–2024: Results of a community screening program in can Tho city, Vietnam","authors":"Son Kim Tran ,&nbsp;Cuong Tan Vo ,&nbsp;Phuong Minh Nguyen ,&nbsp;Dung The Bui ,&nbsp;Chau Minh Tran ,&nbsp;Toan Hoang Ngo ,&nbsp;Minh Van Huynh","doi":"10.1016/j.cegh.2026.102302","DOIUrl":"10.1016/j.cegh.2026.102302","url":null,"abstract":"<div><h3>Problem considered</h3><div>Hypertension (HTN) remains one of the most pressing global health challenges, straining healthcare systems. The May Measurement Month (MMM) campaign aims to raise blood pressure (BP) awareness and address screening gaps. This study screened volunteers aged ≥18 for HTN and cardiovascular risk factors to assess prevalence, awareness, and management effectiveness.</div></div><div><h3>Methods</h3><div>This study employed a cross-sectional, opportunistic survey design. Data were collected from adults aged ≥18 years between 2021 and 2024 as part of the MMM initiative.</div></div><div><h3>Results</h3><div>Among 4105 participants (mean age 53.0 ± 15.3 years), 37.2 % had HTN. Of untreated individuals, 72.5 % were hypertensive, while 53.4 % of treated cases remained uncontrolled (BP ≥ 140/90 mmHg). HTN prevalence rose from 28.9 % (2021) to 47.8 % (2024), with BP control improving to 46.5 % (p &lt; 0.001). HTN was highest in ≥60 years (46.8 %) and lowest in &lt;45 years (15.4 %), while BP control remained stable (33.5 %–35.1 %). Males had higher HTN prevalence, though BP control differences were not significant (p &gt; 0.05). In univariate analyses, HTN was associated with smoking, alcohol use, overweight–obesity, pregnancy, and cardiovascular comorbidities. In the multivariate model from MMM 2021–2024, independent contributors to HTN included older age, heart attack, stroke, diabetes, and physical inactivity, whereas smoking and male sex did not retain statistical significance.</div></div><div><h3>Conclusion</h3><div>The MMM 2021–2024 campaign, conducted during COVID-19, highlighted the need for BP screening in Vietnam. Despite pandemic challenges, undiagnosed and uncontrolled HTN remain major concerns. Standardized screening like MMM remains crucial for detecting high BP and improving HTN management.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"38 ","pages":"Article 102302"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LDL-cholesterol goal achievement and guideline adherence among middle-to older-age Irish adults in a primary care setting 低密度脂蛋白胆固醇目标的实现和指南的遵守在初级保健设置中老年爱尔兰成年人
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-01 Epub Date: 2026-01-07 DOI: 10.1016/j.cegh.2026.102286
Rehab Elhiny , Linda M. O'Keeffe , Seán R. Millar , Stephen Byrne , Margaret Bermingham , Maria Donovan

Background

A significant gap exists between recommended low-density lipoprotein cholesterol (LDL-C) treatment goals and the achievement of these goals in clinical practice. In addition, there remains suboptimal utilization of lipid-lowering therapies (LLT). This study examines the prescribing pattern of LLT and the level of LDL-C goal achievement among Irish adults in a primary care setting. In addition, it identifies patient factors associated with the prescribing of LLT and LDL-C goal achievement.

Methods

This was a cross-sectional analysis of rescreen data from the Mitchelstown Cohort Study. Demographic, medication and diagnosis data were obtained from participant electronic health records. Cardiovascular risk was assessed using the SCORE tool. LDL-C goal achievement was determined using the LDL-C goals set out in the 2011 ESC/EAS guidelines for the management of dyslipidemia.

Results

Among 1183 participants (median age = 65 years), 48.5 % were prescribed LLT, 42 % of whom attained their LDL-C goal. Only 17.5 % were prescribed high-intensity statin therapy and 13 % were prescribed combination therapy. In multivariable analysis, diabetes history, polypharmacy, and hyper-polypharmacy were associated with prescribing LLT. Being male or ≤59 years of age was associated with lower likelihood of LLT prescription. Target LDL-C goal achievement was associated with male sex and age ≤64 or ≥70 years, while BMI 25–29 kg/m2 was associated with lower LDL-C goal achievement.

Conclusion

Dyslipidemia is undertreated in this Irish primary care population with limited use of high-intensity statins. This study highlights the gap between guideline recommendations for LLT prescription and LDL-C target goals and real-world implementation of guidelines.
推荐的低密度脂蛋白胆固醇(LDL-C)治疗目标与临床实践中这些目标的实现存在显著差距。此外,降脂疗法(LLT)的应用仍不理想。本研究考察了初级保健环境中爱尔兰成年人的LLT处方模式和LDL-C目标实现水平。此外,它还确定了与LLT处方和LDL-C目标实现相关的患者因素。方法:对来自mitchell stown队列研究的再筛查数据进行横断面分析。从参与者的电子健康记录中获得人口统计、药物和诊断数据。使用SCORE工具评估心血管风险。LDL-C目标的实现是根据2011年ESC/EAS血脂异常管理指南中设定的LDL-C目标来确定的。结果在1183名参与者(中位年龄= 65岁)中,48.5%的人接受了LLT治疗,其中42%的人达到了LDL-C目标。只有17.5%的患者接受了高强度他汀类药物治疗,13%的患者接受了联合治疗。在多变量分析中,糖尿病病史、多重用药和过度多重用药与处方LLT相关。男性或≤59岁与LLT处方的可能性较低相关。LDL-C目标达成与男性性别、年龄≤64岁或≥70岁相关,BMI 25-29 kg/m2与较低的LDL-C目标达成相关。结论:在爱尔兰初级保健人群中,由于高强度他汀类药物的使用有限,血脂异常治疗不足。本研究强调了指南建议的LLT处方和LDL-C目标目标与指南的实际实施之间的差距。
{"title":"LDL-cholesterol goal achievement and guideline adherence among middle-to older-age Irish adults in a primary care setting","authors":"Rehab Elhiny ,&nbsp;Linda M. O'Keeffe ,&nbsp;Seán R. Millar ,&nbsp;Stephen Byrne ,&nbsp;Margaret Bermingham ,&nbsp;Maria Donovan","doi":"10.1016/j.cegh.2026.102286","DOIUrl":"10.1016/j.cegh.2026.102286","url":null,"abstract":"<div><h3>Background</h3><div>A significant gap exists between recommended low-density lipoprotein cholesterol (LDL-C) treatment goals and the achievement of these goals in clinical practice. In addition, there remains suboptimal utilization of lipid-lowering therapies (LLT). This study examines the prescribing pattern of LLT and the level of LDL-C goal achievement among Irish adults in a primary care setting. In addition, it identifies patient factors associated with the prescribing of LLT and LDL-C goal achievement.</div></div><div><h3>Methods</h3><div>This was a cross-sectional analysis of rescreen data from the Mitchelstown Cohort Study. Demographic, medication and diagnosis data were obtained from participant electronic health records. Cardiovascular risk was assessed using the SCORE tool. LDL-C goal achievement was determined using the LDL-C goals set out in the 2011 ESC/EAS guidelines for the management of dyslipidemia.</div></div><div><h3>Results</h3><div>Among 1183 participants (median age = 65 years), 48.5 % were prescribed LLT, 42 % of whom attained their LDL-C goal. Only 17.5 % were prescribed high-intensity statin therapy and 13 % were prescribed combination therapy. In multivariable analysis, diabetes history, polypharmacy, and hyper-polypharmacy were associated with prescribing LLT. Being male or ≤59 years of age was associated with lower likelihood of LLT prescription. Target LDL-C goal achievement was associated with male sex and age ≤64 or ≥70 years, while BMI 25–29 kg/m<sup>2</sup> was associated with lower LDL-C goal achievement.</div></div><div><h3>Conclusion</h3><div>Dyslipidemia is undertreated in this Irish primary care population with limited use of high-intensity statins. This study highlights the gap between guideline recommendations for LLT prescription and LDL-C target goals and real-world implementation of guidelines.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"38 ","pages":"Article 102286"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145980501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Undernutrition and recovery in Pulmonary Tuberculosis: Insights from a study in Lucknow, India 营养不良与肺结核的康复:来自印度勒克瑙一项研究的见解
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-01 Epub Date: 2025-12-24 DOI: 10.1016/j.cegh.2025.102270
Purnoor Kaur , Monika Agarwal , M.A. Akshata , V.K. Singh , Surya Kant

Problem considered

Undernutrition is a major risk factor for tuberculosis (TB), compromising immunity and adversely affecting treatment outcomes. India bears the highest global TB burden, with a large proportion of patients experiencing poor nutritional status.

Methods

A prospective observational study was conducted in 2022 among 272 adult pulmonary TB patients enrolled in six tuberculosis units of Lucknow district. Data were collected through a semi-structured questionnaire, anthropometric measurements, and 24-h dietary recall. Nutritional status was assessed using body mass index (BMI), and dietary intake was analysed for adequacy of energy and protein. Treatment outcomes were obtained from programmatic records.

Results

The mean age of participants was 33 ± 12 years, with males comprising 62.8 %. At treatment initiation, 61 % were undernourished (BMI <18.5), and only 32 % attained normal weight by completion. The mean caloric intake was 1662.9 kcal, which was below recommended requirements, while protein intake was also insufficient. Although 99 % were enrolled in Nikshay Poshan Yojana, only 4.7 % reported receiving benefits. Dietary diversity was adequate in 66.9 % of participants. Overall, 89.3 % achieved successful treatment outcomes, but no statistically significant association was observed between BMI at treatment completion and outcome.

Conclusion

Undernutrition was highly prevalent among TB patients, with minimal nutritional recovery despite treatment. Suboptimal dietary intake and poor implementation of nutritional support schemes highlight the need for integrated interventions. Strengthening delivery of schemes like Nikshay Poshan Yojana and promoting dietary adequacy are critical to improving TB outcomes.
考虑到的问题营养不良是结核病的一个主要危险因素,会损害免疫力并对治疗结果产生不利影响。印度是全球结核病负担最重的国家,很大一部分患者营养状况不佳。方法于2022年对勒克瑙地区6个结核病科室的272例成年肺结核患者进行前瞻性观察研究。数据通过半结构化问卷、人体测量和24小时饮食回忆收集。利用身体质量指数(BMI)评估营养状况,并分析饮食摄入是否足够能量和蛋白质。从方案记录中获得治疗结果。结果参与者平均年龄为33岁 ± 12岁,男性占62.8 %。在治疗开始时,61% %营养不良(BMI <18.5),只有32% %在完成治疗后达到正常体重。平均热量摄入量为1662.9 kcal,低于推荐要求,蛋白质摄入量也不足。虽然99% %的人参加了Nikshay Poshan Yojana,但只有4.7% %的人报告获得了福利。66.9% %的参与者饮食多样性充足。总体而言,89.3% %获得了成功的治疗结果,但在治疗完成时BMI与结果之间没有统计学意义上的显著关联。结论结核患者营养不良发生率高,经治疗后营养恢复程度低。次优膳食摄入量和营养支持计划实施不力突出了综合干预措施的必要性。加强Nikshay Poshan Yojana等计划的实施和促进饮食充足性对于改善结核病结果至关重要。
{"title":"Undernutrition and recovery in Pulmonary Tuberculosis: Insights from a study in Lucknow, India","authors":"Purnoor Kaur ,&nbsp;Monika Agarwal ,&nbsp;M.A. Akshata ,&nbsp;V.K. Singh ,&nbsp;Surya Kant","doi":"10.1016/j.cegh.2025.102270","DOIUrl":"10.1016/j.cegh.2025.102270","url":null,"abstract":"<div><h3>Problem considered</h3><div>Undernutrition is a major risk factor for tuberculosis (TB), compromising immunity and adversely affecting treatment outcomes. India bears the highest global TB burden, with a large proportion of patients experiencing poor nutritional status.</div></div><div><h3>Methods</h3><div>A prospective observational study was conducted in 2022 among 272 adult pulmonary TB patients enrolled in six tuberculosis units of Lucknow district. Data were collected through a semi-structured questionnaire, anthropometric measurements, and 24-h dietary recall. Nutritional status was assessed using body mass index (BMI), and dietary intake was analysed for adequacy of energy and protein. Treatment outcomes were obtained from programmatic records.</div></div><div><h3>Results</h3><div>The mean age of participants was 33 ± 12 years, with males comprising 62.8 %. At treatment initiation, 61 % were undernourished (BMI &lt;18.5), and only 32 % attained normal weight by completion. The mean caloric intake was 1662.9 kcal, which was below recommended requirements, while protein intake was also insufficient. Although 99 % were enrolled in Nikshay Poshan Yojana, only 4.7 % reported receiving benefits. Dietary diversity was adequate in 66.9 % of participants. Overall, 89.3 % achieved successful treatment outcomes, but no statistically significant association was observed between BMI at treatment completion and outcome.</div></div><div><h3>Conclusion</h3><div>Undernutrition was highly prevalent among TB patients, with minimal nutritional recovery despite treatment. Suboptimal dietary intake and poor implementation of nutritional support schemes highlight the need for integrated interventions. Strengthening delivery of schemes like Nikshay Poshan Yojana and promoting dietary adequacy are critical to improving TB outcomes.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"38 ","pages":"Article 102270"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lived realities of family engagement: A thematic exploration of the family adoption program 家庭参与的生活现实:家庭收养计划的主题探索
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-01 Epub Date: 2026-02-05 DOI: 10.1016/j.cegh.2026.102305
Amogha shree, S. Rashmi, K. Shruddha, Anchu R. Nath, D. Sunil Kumar

Background

The Family Adoption Program (FAP) was introduced to strengthen community engagement and foster experiential learning in Indian medical education. While most evaluations focus on student perspectives, the lived experiences of families remain underexplored. This study aimed to explore the perceptions, experiences, and suggestions of families participating in the FAP in rural Karnataka.

Methodology

A qualitative study was conducted in June 2025 in the villages of Hanchya and Rammanahalli, Karnataka, using a phenomenological approach. Purposive sampling method was used to identify the families who had participated in the program for at least three years. Data were collected through semi-structured, in-depth interviews conducted in Kannada, audio-recorded, and transcribed verbatim. Thematic analysis was performed to identify key patterns across narratives.

Results

Twenty families participated in this study. Seven themes emerged(Chepuru et al., 2025 Jan) 1: navigating language and communication,(Shekhawat et al., 2025 Jan 31) 2 disruption versus engagement in daily life,(Shree et al., 2024 Jul 1) 3 scope and nature of student interventions,(Yalamanchili et al., 2023 Feb) 4 perceived gaps in continuity of care,(Shikha et al., 2024 Feb) 5 engagement with health camps,(Reshmi et al., 2024 Aug) 6 relationship dynamics with student visitors, and(Arumugam et al., 2022 Jul 28) 7 community suggestions for program enhancement. Families valued students’ ability to communicate in the local language, provide health education, and offer basic clinical checks, which raised trust and better rapport. However, barriers such as linguistic disconnect, inconvenient scheduling, limited follow-up, and predominantly survey-based interactions diminished program effectiveness.

Conclusion

Families perceive FAP as beneficial when visits are regular, with lesser language barrier, and service-oriented. Continuous and regular visits with adaptable schedules to family needs, and including organized feedback mechanisms can improve both community impact and student learning.
引入家庭收养方案(FAP)是为了加强社区参与,促进印度医学教育中的体验式学习。虽然大多数评估都集中在学生的观点上,但家庭的生活经历仍未得到充分探讨。本研究旨在探讨卡纳塔克邦农村家庭参与FAP的看法、经验和建议。方法2025年6月在卡纳塔克邦的Hanchya和Rammanahalli村进行了定性研究,采用现象学方法。采用有目的抽样的方法,确定参加该计划至少三年的家庭。数据通过半结构化的深度访谈收集,以卡纳达语进行,录音,并逐字转录。进行主题分析以确定叙事中的关键模式。结果20个家庭参与了本研究。出现了七个主题(Chepuru等人,2025年1月)1:导航语言和交流,(Shekhawat等人,2025年1月31日)2日常生活中的干扰与参与,(Shree等人,2024年7月1日)3学生干预的范围和性质,(Yalamanchili等人,2023年2月)4护理连续性的感知差距,(Shikha等人,2024年2月)5与健康营地的参与,(Reshmi等人,2024年8月)6与学生访客的关系动态,以及(Arumugam等人,2022年7月28日)7社区对项目改进的建议。家庭重视学生用当地语言交流的能力,提供健康教育,并提供基本的临床检查,这增加了信任和更好的关系。然而,语言不通、不方便的安排、有限的随访和主要基于调查的互动等障碍降低了项目的有效性。结论定期就诊、语言障碍小、以服务为导向的家庭认为FAP是有益的。根据家庭需要,按照可调整的时间表进行持续和定期的访问,并包括有组织的反馈机制,可以改善社区影响和学生学习。
{"title":"Lived realities of family engagement: A thematic exploration of the family adoption program","authors":"Amogha shree,&nbsp;S. Rashmi,&nbsp;K. Shruddha,&nbsp;Anchu R. Nath,&nbsp;D. Sunil Kumar","doi":"10.1016/j.cegh.2026.102305","DOIUrl":"10.1016/j.cegh.2026.102305","url":null,"abstract":"<div><h3>Background</h3><div>The Family Adoption Program (FAP) was introduced to strengthen community engagement and foster experiential learning in Indian medical education. While most evaluations focus on student perspectives, the lived experiences of families remain underexplored. This study aimed to explore the perceptions, experiences, and suggestions of families participating in the FAP in rural Karnataka.</div></div><div><h3>Methodology</h3><div>A qualitative study was conducted in June 2025 in the villages of Hanchya and Rammanahalli, Karnataka, using a phenomenological approach. Purposive sampling method was used to identify the families who had participated in the program for at least three years. Data were collected through semi-structured, in-depth interviews conducted in Kannada, audio-recorded, and transcribed verbatim. Thematic analysis was performed to identify key patterns across narratives.</div></div><div><h3>Results</h3><div>Twenty families participated in this study. Seven themes emerged(Chepuru et al., 2025 Jan) 1: navigating language and communication,(Shekhawat et al., 2025 Jan 31) 2 disruption versus engagement in daily life,(Shree et al., 2024 Jul 1) 3 scope and nature of student interventions,(Yalamanchili et al., 2023 Feb) 4 perceived gaps in continuity of care,(Shikha et al., 2024 Feb) 5 engagement with health camps,(Reshmi et al., 2024 Aug) 6 relationship dynamics with student visitors, and(Arumugam et al., 2022 Jul 28) 7 community suggestions for program enhancement. Families valued students’ ability to communicate in the local language, provide health education, and offer basic clinical checks, which raised trust and better rapport. However, barriers such as linguistic disconnect, inconvenient scheduling, limited follow-up, and predominantly survey-based interactions diminished program effectiveness.</div></div><div><h3>Conclusion</h3><div>Families perceive FAP as beneficial when visits are regular, with lesser language barrier, and service-oriented. Continuous and regular visits with adaptable schedules to family needs, and including organized feedback mechanisms can improve both community impact and student learning.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"38 ","pages":"Article 102305"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147397804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Access to sexual health services among young Brazilians: Analysis in light of social determinants of health 巴西年轻人获得性健康服务的情况:根据健康的社会决定因素进行分析
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-01 Epub Date: 2026-02-13 DOI: 10.1016/j.cegh.2026.102307
William Caracas Moreira , Guilherme Frederico Abdul Nour , Mônica Oliveira Batista Oriá , Ana Kelve de Castro Damasceno , Jordana de Almeida Nogueira , Oriana Deyze Correia Paiva Leadebal , Hellen Lívia Oliveira Catunda Ferreira , Ana Karina Bezerra Pinheiro

Objective

Analyze young people's access to two sexual health services in two macro-regions of Brazil.

Methods

A cross-sectional study was conducted with 301 young people aged 15–24 years at two sexual health services in two cities, headquarters of macro-regions in Paraíba, Brazil. Data were collected from February to July 2021 using a validated form and analyzed using descriptive statistics, chi-square tests, and prevalence ratios, based on the World Health Organization's Social Determinants of Health.

Results

301 young people, average age 20.83 (±2.30) years, predominantly male (51.50%), non-white (72.10%), cisgender (96.70%), and heterosexual (58.10%). Difficulty accessing services (14.60%) was influenced by income, age group, and discrimination. Difficulty in undergoing rapid testing (22.60%) was influenced by education, work, alcohol consumption, and risky sexual behaviors. Difficulty in acquiring condoms was influenced by victimization by sexual violence, history of incarceration, and transactional sex.

Conclusion

These factors had a direct impact on young people's access to sexual health services.
目的分析巴西两个宏观地区年轻人获得两种性健康服务的情况。方法采用横断面研究方法,对巴西Paraíba大区域总部两个城市性健康服务机构的301名15-24岁年轻人进行调查。数据收集于2021年2月至7月,使用经过验证的表格,并根据世界卫生组织的《健康的社会决定因素》,使用描述性统计、卡方检验和患病率进行分析。结果青年301例,平均年龄20.83(±2.30)岁,男性占51.50%,非白人占72.10%,顺性别占96.70%,异性恋占58.10%。获得服务的困难(14.60%)受收入、年龄组和歧视的影响。难以接受快速检测(22.60%)受教育、工作、饮酒和危险的性行为的影响。性暴力受害者、监禁史和交易性行为影响了获得避孕套的困难。结论这些因素对青少年获得性健康服务有直接影响。
{"title":"Access to sexual health services among young Brazilians: Analysis in light of social determinants of health","authors":"William Caracas Moreira ,&nbsp;Guilherme Frederico Abdul Nour ,&nbsp;Mônica Oliveira Batista Oriá ,&nbsp;Ana Kelve de Castro Damasceno ,&nbsp;Jordana de Almeida Nogueira ,&nbsp;Oriana Deyze Correia Paiva Leadebal ,&nbsp;Hellen Lívia Oliveira Catunda Ferreira ,&nbsp;Ana Karina Bezerra Pinheiro","doi":"10.1016/j.cegh.2026.102307","DOIUrl":"10.1016/j.cegh.2026.102307","url":null,"abstract":"<div><h3>Objective</h3><div>Analyze young people's access to two sexual health services in two macro-regions of Brazil.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted with 301 young people aged 15–24 years at two sexual health services in two cities, headquarters of macro-regions in Paraíba, Brazil. Data were collected from February to July 2021 using a validated form and analyzed using descriptive statistics, chi-square tests, and prevalence ratios, based on the World Health Organization's Social Determinants of Health.</div></div><div><h3>Results</h3><div>301 young people, average age 20.83 (±2.30) years, predominantly male (51.50%), non-white (72.10%), cisgender (96.70%), and heterosexual (58.10%). Difficulty accessing services (14.60%) was influenced by income, age group, and discrimination. Difficulty in undergoing rapid testing (22.60%) was influenced by education, work, alcohol consumption, and risky sexual behaviors. Difficulty in acquiring condoms was influenced by victimization by sexual violence, history of incarceration, and transactional sex.</div></div><div><h3>Conclusion</h3><div>These factors had a direct impact on young people's access to sexual health services.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"38 ","pages":"Article 102307"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147397807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global research status and hot-spots of Sirt1 in aging: a bibliometric analysis based from 2005 to 2024 Sirt1在老龄化中的全球研究现状与热点:基于2005 - 2024年的文献计量学分析
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-01 Epub Date: 2026-03-06 DOI: 10.1016/j.cegh.2026.102325
Shiyao Liu , Congcong Song , Ziyi Liu , Yushan Li , Huimei Chen , Wei Chen , Na Wang

Background

Aging is a complex physiological process, regulated by multiple intertwined mechanisms. In this process, Sirt1 played a vital role with evidences increasing continually. Given the rapid expansion of research in this area, a comprehensive overview of the intellectual landscape is needed to guide future investigations. Based on, we conducted a bibliometric analysis of the relevant literature and visualized the results. Our study aimed to consolidate the current knowledge and provide insights into evolving research trends, thereby contributing to a deeper understanding of Sirt1's roles in aging process.

Methods

On August 14th, 2024, we retrieved 2434 issues in Web of Science Core Collection (searching period from 2005 to 2024). Using VOSviewer, Citespace and bibliometrix, we analyzed these records in terms of annual publications/citations, spatiotemporal distribution, collaborations between regions/institutions/authors, co-references, and keywords.

Result

We identified a stable development trend of researching on Sirt1 and aging. In the last 2 decades, the average growth rate of publication numbers was 34.52%, while in recent 5 years it fell to 10.8%. So far, China and the United States were more conductive and influential in this field. Their publications accounted for 39.56% and 26.17%, respectively. Of interests, since Hungary's publication numbers just accounted for 7% of the publications worldly, it had the strongest average citations. Besides, some institutions and countries had varieties of publications, but weak link strength, meaning further collaborations of them were needed in future study. Importantly, keywords analysis indicated that oxidative stress and calorie restriction were the main hot-spots of this field. Besides, inflammation, DNA damage, metabolism, mitochondrial dysfunction and autophagy might be new research directions in Sirt1 and aging.

Conclusions

Above all, this study provided further insights into recent advances and future progression in researches on Sirt1 and aging.
衰老是一个复杂的生理过程,受多种相互交织的机制调控。在这一过程中,Sirt1发挥了至关重要的作用,证据不断增加。鉴于这一领域的研究迅速扩大,需要对智力景观进行全面的概述,以指导未来的研究。在此基础上,我们对相关文献进行了文献计量学分析,并将结果可视化。我们的研究旨在巩固现有的知识,并为不断发展的研究趋势提供见解,从而有助于更深入地了解Sirt1在衰老过程中的作用。方法于2024年8月14日检索Web of Science核心馆藏2434期(检索期2005 - 2024)。利用VOSviewer、Citespace和bibliometrix对这些文献进行了年度发表/被引、时空分布、地区/机构/作者合作、共同参考文献和关键词等方面的分析。结果Sirt1与衰老的研究有稳定的发展趋势。在过去的20年里,出版数量的平均增长率为34.52%,而近5年下降到10.8%。到目前为止,中美两国在这一领域的导向性和影响力更大。发表量占比分别为39.56%和26.17%。有趣的是,由于匈牙利的出版物数量仅占全球出版物的7%,它的平均引用量最高。此外,一些机构和国家的出版物种类繁多,但链接强度较弱,需要在未来的研究中进一步合作。重要的是,关键词分析表明,氧化应激和热量限制是该领域的主要热点。此外,炎症、DNA损伤、代谢、线粒体功能障碍、自噬等可能是Sirt1与衰老研究的新方向。总之,本研究为Sirt1与衰老研究的最新进展和未来进展提供了进一步的见解。
{"title":"Global research status and hot-spots of Sirt1 in aging: a bibliometric analysis based from 2005 to 2024","authors":"Shiyao Liu ,&nbsp;Congcong Song ,&nbsp;Ziyi Liu ,&nbsp;Yushan Li ,&nbsp;Huimei Chen ,&nbsp;Wei Chen ,&nbsp;Na Wang","doi":"10.1016/j.cegh.2026.102325","DOIUrl":"10.1016/j.cegh.2026.102325","url":null,"abstract":"<div><h3>Background</h3><div>Aging is a complex physiological process, regulated by multiple intertwined mechanisms. In this process, Sirt1 played a vital role with evidences increasing continually. Given the rapid expansion of research in this area, a comprehensive overview of the intellectual landscape is needed to guide future investigations. Based on, we conducted a bibliometric analysis of the relevant literature and visualized the results. Our study aimed to consolidate the current knowledge and provide insights into evolving research trends, thereby contributing to a deeper understanding of Sirt1's roles in aging process.</div></div><div><h3>Methods</h3><div>On August 14th, 2024, we retrieved 2434 issues in Web of Science Core Collection (searching period from 2005 to 2024). Using VOSviewer, Citespace and bibliometrix, we analyzed these records in terms of annual publications/citations, spatiotemporal distribution, collaborations between regions/institutions/authors, co-references, and keywords.</div></div><div><h3>Result</h3><div>We identified a stable development trend of researching on Sirt1 and aging. In the last 2 decades, the average growth rate of publication numbers was 34.52%, while in recent 5 years it fell to 10.8%. So far, China and the United States were more conductive and influential in this field. Their publications accounted for 39.56% and 26.17%, respectively. Of interests, since Hungary's publication numbers just accounted for 7% of the publications worldly, it had the strongest average citations. Besides, some institutions and countries had varieties of publications, but weak link strength, meaning further collaborations of them were needed in future study. Importantly, keywords analysis indicated that oxidative stress and calorie restriction were the main hot-spots of this field. Besides, inflammation, DNA damage, metabolism, mitochondrial dysfunction and autophagy might be new research directions in Sirt1 and aging.</div></div><div><h3>Conclusions</h3><div>Above all, this study provided further insights into recent advances and future progression in researches on Sirt1 and aging.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"38 ","pages":"Article 102325"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147398239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge, attitudes, and practices regarding human papillomavirus vaccination among teenage girls with sickle cell disease at Usmanu Danfodiyo University teaching hospital, Sokoto, Nigeria 尼日利亚索科托Usmanu Danfodiyo大学教学医院镰状细胞病少女中关于人乳头瘤病毒疫苗接种的知识、态度和做法
IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-01 Epub Date: 2026-02-12 DOI: 10.1016/j.cegh.2026.102318
Ibrahim Abdulqadir , Ahmad Abubakar , Muhammad Umar Sa'id , Hadiza Muhammad Ango , Jonas-Attabo Samson Apeh , Abdallah Ahmed Adam Belal , Adam Dawria , Ali Mohieldin , Abdelsalam Mohamed Daoud Yahya , Sami M. HasapAla , Aeshah Alshehri , Fatima Garba Muhammad , Bello Arkilla Magaji

Background

Sickle Cell Disease (SCD) impairs immune function and increases susceptibility to infections such as Human Papillomavirus (HPV), a primary cause of cervical cancer. Both conditions pose major public health challenges in Nigeria, where overall HPV awareness and vaccine uptake remain low. This study assessed the knowledge, attitudes, and practices (KAP) regarding HPV vaccination among teenage girls with confirmed SCD in Sokoto State, aiming to inform targeted preventive strategies.

Methods

This cross-sectional study was conducted at Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto, involving 85 teenage girls with confirmed SCD. Data were collected using a pretested semi-structured questionnaire administered via ODK, and analysed using descriptive and inferential statistics with Excel and Jamovi respectively.

Results

The 85 participants (mean age 15.6 years) were predominantly of the HbSS phenotype (82%). They were mostly diagnosed before the age of five (93%) and managed with hydroxyurea (79%). HPV knowledge was poor: only 8% correctly linked HPV to cervical cancer or knew the correct vaccination age. While 96% feared cervical cancer, fewer than half considered the vaccine useful (47%) or safe (48%). Despite 54% expressing willingness, the overall vaccine uptake was low (12%). Significant associations were observed between KAP and variables including age, education, and history of painful SCD crisis.

Conclusion

These findings reveal significant gaps in HPV vaccine knowledge and uptake among high-risk population. We recommend immediate, targeted awareness campaigns, government support, and the integration of HPV vaccination into routine SCD hospital care programs.
背景镰状细胞病(SCD)损害免疫功能,增加对人类乳头瘤病毒(HPV)等感染的易感性,HPV是宫颈癌的主要原因。这两种情况对尼日利亚的公共卫生构成重大挑战,在尼日利亚,人乳头瘤病毒的总体认识和疫苗接种率仍然很低。本研究评估了索科托州确诊SCD的少女中关于HPV疫苗接种的知识、态度和实践(KAP),旨在为有针对性的预防策略提供信息。方法横断面研究在索科托Usmanu Danfodiyo大学教学医院(UDUTH)进行,涉及85名确诊SCD的少女。采用ODK预测半结构化问卷收集数据,分别使用Excel和Jamovi进行描述性统计和推理统计分析。结果85例参与者(平均年龄15.6岁)以HbSS表型为主(82%)。他们大多在5岁前被诊断出来(93%),并用羟基脲治疗(79%)。HPV知识贫乏:只有8%的人正确地将HPV与宫颈癌联系起来,或者知道正确的疫苗接种年龄。虽然96%的人担心宫颈癌,但只有不到一半的人认为疫苗有用(47%)或安全(48%)。尽管54%的人表示愿意接种疫苗,但总体疫苗接种率很低(12%)。KAP与年龄、教育程度和疼痛性SCD危象史等变量之间存在显著关联。结论高危人群在HPV疫苗知识和接种方面存在明显差距。我们建议立即开展有针对性的宣传活动,政府支持,并将HPV疫苗接种纳入常规SCD医院护理计划。
{"title":"Knowledge, attitudes, and practices regarding human papillomavirus vaccination among teenage girls with sickle cell disease at Usmanu Danfodiyo University teaching hospital, Sokoto, Nigeria","authors":"Ibrahim Abdulqadir ,&nbsp;Ahmad Abubakar ,&nbsp;Muhammad Umar Sa'id ,&nbsp;Hadiza Muhammad Ango ,&nbsp;Jonas-Attabo Samson Apeh ,&nbsp;Abdallah Ahmed Adam Belal ,&nbsp;Adam Dawria ,&nbsp;Ali Mohieldin ,&nbsp;Abdelsalam Mohamed Daoud Yahya ,&nbsp;Sami M. HasapAla ,&nbsp;Aeshah Alshehri ,&nbsp;Fatima Garba Muhammad ,&nbsp;Bello Arkilla Magaji","doi":"10.1016/j.cegh.2026.102318","DOIUrl":"10.1016/j.cegh.2026.102318","url":null,"abstract":"<div><h3>Background</h3><div>Sickle Cell Disease (SCD) impairs immune function and increases susceptibility to infections such as Human Papillomavirus (HPV), a primary cause of cervical cancer. Both conditions pose major public health challenges in Nigeria, where overall HPV awareness and vaccine uptake remain low. This study assessed the knowledge, attitudes, and practices (KAP) regarding HPV vaccination among teenage girls with confirmed SCD in Sokoto State, aiming to inform targeted preventive strategies.</div></div><div><h3>Methods</h3><div>This cross-sectional study was conducted at Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto, involving 85 teenage girls with confirmed SCD. Data were collected using a pretested semi-structured questionnaire administered via ODK, and analysed using descriptive and inferential statistics with Excel and Jamovi respectively.</div></div><div><h3>Results</h3><div>The 85 participants (mean age 15.6 years) were predominantly of the HbSS phenotype (82%). They were mostly diagnosed before the age of five (93%) and managed with hydroxyurea (79%). HPV knowledge was poor: only 8% correctly linked HPV to cervical cancer or knew the correct vaccination age. While 96% feared cervical cancer, fewer than half considered the vaccine useful (47%) or safe (48%). Despite 54% expressing willingness, the overall vaccine uptake was low (12%). Significant associations were observed between KAP and variables including age, education, and history of painful SCD crisis.</div></div><div><h3>Conclusion</h3><div>These findings reveal significant gaps in HPV vaccine knowledge and uptake among high-risk population. We recommend immediate, targeted awareness campaigns, government support, and the integration of HPV vaccination into routine SCD hospital care programs.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"38 ","pages":"Article 102318"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147398237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Clinical Epidemiology and Global Health
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1