Clinical Epidemiology and Global Health最新文献

{"title":"Does attachment and prenatal depression affect maternal health-promoting lifestyle during pregnancy? A cross-sectional study","authors":"Rufidah Maulina ,&nbsp;Su-Chen Kuo ,&nbsp;Chieh-Yu Liu ,&nbsp;Yu Ying Lu ,&nbsp;Siti Khuzaiyah ,&nbsp;Rafael A. Caparros-Gonzalez","doi":"10.1016/j.cegh.2024.101904","DOIUrl":"10.1016/j.cegh.2024.101904","url":null,"abstract":"<div><h3>Introduction</h3><div>A healthy lifestyle during pregnancy is crucial for improving maternal and infant outcomes. Maternal-fetal attachment and maternal prenatal depression have been identified as factors influencing maternal lifestyle during pregnancy. This study aimed to investigate the relationship between maternal-fetal attachment, maternal prenatal depression, and a healthy lifestyle among pregnant women.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted among 224 pregnant women in their third trimester, attending an antenatal appointment at a community health center in Surakarta, Indonesia, from July to September 2019.</div></div><div><h3>Results</h3><div>Bivariate analysis revealed significant associations between education (p = 0.024), religion (p = 0.026), employment (p = 0.012), income (p = 0.016), parity (p = 0.026), maternal depression (p &lt; 0.01), maternal-fetal attachment (p &lt; 0.001), and a health-promoting lifestyle. However, factors such as age, living arrangement, gestational age, a planned pregnancy, previous miscarriages, pre-pregnancy diseases, pre-pregnancy complications, and a private health insurance showed no significant associations. Hierarchical multiple linear regression indicated that maternal-fetal attachment (p &lt; 0.05) and maternal depression (p &lt; 0.001) were the only predictors of pregnant women's health-promoting lifestyles (R2 = 0.373, ΔR = 0.251).</div></div><div><h3>Conclusion</h3><div>Maternal-fetal attachment and maternal prenatal depression are key predictors of adopting a health-promoting lifestyle during pregnancy. These findings highlight the importance of maternal psychological well-being as part of a comprehensive antenatal care.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101904"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and risk factors of recurrent ocular injuries: A multicenter retrospective cohort study in four community hospitals, central Thailand","authors":"Panrawee Sertsuwankul ,&nbsp;Chanapat Limprungpattanakit ,&nbsp;Panhathai Yaisiri ,&nbsp;Ploypun Narindrarangkura ,&nbsp;Sethapong Lertsakulbunlue","doi":"10.1016/j.cegh.2024.101892","DOIUrl":"10.1016/j.cegh.2024.101892","url":null,"abstract":"<div><h3>Introduction</h3><div>Recurrent ocular injuries increase the risk of long-term ocular complications, which increases public health and economic burden. This study assesses the incidence and risk factors for recurrent ocular injuries in community hospitals in central Thailand, where industrial and agricultural activities heighten risk.</div></div><div><h3>Methods</h3><div>This retrospective cohort study enrolled patients from four rural community hospitals over six years (October 1, 2018, to September 17, 2024). Patients with ocular injuries were identified using ICD-10 codes, excluding individuals under 20 and revisits. Data collected included patient demographics, injury characteristics, and healthcare access behaviors. Time-to-event analysis begins from the first ocular injury until a subsequent event or study ends. Statistical analyses identified risk factors, with recurrent events analyzed using the Wei-Lin-Weissfeld model.</div></div><div><h3>Results</h3><div>Of 7189 ocular injury cases, 4373 (60.8 %) were male, with a median age of 43 (IQR 31–57). Most injuries (79.2 %) occurred in industrial settings. Recurrent injuries accounted for 1628 cases (22.7 %), with a rate of 7.6 per 100 person-years. Multivariable analysis showed higher recurrence risk for males (aHR:1.30, 95%CI: 1.07–1.57), age ≥60 (aHR:1.32, 95%CI: 1.04–1.68), and industrial activity (aHR:1.41, 95%CI: 1.10–1.80). Non-urgency cases (aHR:3.32, 95%CI: 1.49–7.42), visits to larger (M2 versus F2) hospitals (aHR:2.98, 95%CI: 1.43–6.20) and outpatient department (aHR:1.43, 95%CI: 1.18–1.74) compared to the emergency department were also linked to higher recurrence.</div></div><div><h3>Conclusion</h3><div>The findings highlight a substantial incidence of recurrent ocular injuries in rural Thailand, predominantly affecting males and older adults, particularly in industrial sectors. Targeted public health interventions are necessary to enhance injury prevention strategies.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101892"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic characteristics, risk factors and genotype distribution of hepatitis C virus in Bosnia and Herzegovina: Single center experience","authors":"Ivana Talić Drlje ,&nbsp;Božo Šušak ,&nbsp;Siniša Skočibušić ,&nbsp;Borka Tutiš ,&nbsp;Sanja Jakovac ,&nbsp;Jurica Arapović","doi":"10.1016/j.cegh.2024.101845","DOIUrl":"10.1016/j.cegh.2024.101845","url":null,"abstract":"<div><h3>Objectives</h3><div>Viral hepatitis presents a significant public health challenge due to its slow progression leading to severe liver disease and death. The aim of this research is to identify risk behaviors and groups associated with hepatitis C, with the goal of directing prevention measures, increasing mass testing, and potentially facilitating treatment in Bosnia and Herzegovina.</div></div><div><h3>Methods</h3><div>A case-control study was conducted from 2017 to 2022, involving 69 anti-HCV-positive and 70 control respondents matched for gender and age. After obtaining of informed consent, respondents completed a questionnaire focusing on sociodemographic status and potential risk factors for HCV-infection. Molecular quantification tests were carried out, and genotyping was performed for respondents positive for HCV RNA.</div></div><div><h3>Results</h3><div>In this study, we found statistically significantly that anti-HCV respondents are more frequently male, of younger age, with lower educational levels, unemployed, and often unmarried, predominantly residing in urban areas. Behaviors such as tattooing, piercing, contact with others' blood, drug usage, intimate relationships with hepatitis B or C positive partners and having more than two sexual partners in the last 12 months were statistically significantly more common among anti-HCV-positive individuals compared to the control group. However, binary logistic regression analysis identified drug usage as significant risk factor for HCV-infection.</div></div><div><h3>Conclusion</h3><div>Due to the fact that the numbers of drug users are continuously increasing among people of younger age, it is very important to direct prevention measures towards this population.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101845"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of healthcare workers' social support on compliance to medication in multi drug resistant tuberculosis patients at the Regional General Hospital of Dr. Saiful Anwar","authors":"Fauzan Adima,&nbsp;Merita Arini","doi":"10.1016/j.cegh.2024.101890","DOIUrl":"10.1016/j.cegh.2024.101890","url":null,"abstract":"<div><h3>Introduction</h3><div>Tuberculosis (TB) remains a significant public health issue that poses a worldwide challenge. Indonesia has the second highest incidence of tuberculosis (TB) globally, following India. The Ministry of Health of the Republic of Indonesia reported that the estimated incidence of tuberculosis (TB) in Indonesia in 2021 is 969,000 cases, which corresponds to a rate of 354 cases per 100,000 population. Patients with drug-resistant strains of tuberculosis require an extended duration of treatment due to its classification as a chronic illness. Individuals afflicted with tuberculosis (TB) will face a complex array of challenges, including significant levels of stress. In addition to medical intervention, they will also require social assistance from their family and community. According to Johnson and Johnson (2009), health workers can provide role and social support in the form of emotional support, informational support, instrumental support, and assessment and appreciation support. Emotional support refers to provision of emotional encouragement and motivation by health workers. Informational support refers to delivery of information offered by health workers. Instrumental support refers to provision of material assistance to patient that includes transportation, financial, and access support to TBC treatment by health workers. Appreciation support refers to encouragement, praise, or corrective feedback given by health workers to the patient on TB-RO treatment. This study aims to evaluate the influence of healthcare professionals' social support on medication adherence in patients with multi drug resistant tuberculosis (MDR-TB) at the Regional General Hospital of Dr. Saiful Anwar in Malang.</div></div><div><h3>Method</h3><div>This study employed a quantitative research methodology, specifically utilizing a cross-sectional study design. The study included 78 MDR-TB patients currently receiving treatment at RSUD Dr. Saiful Anwar Malang, located in Indonesia's East Java Province. In 2023, the Ministry of Health registered these patients in its Tuberculosis Information System.</div></div><div><h3>Results</h3><div>The most common gender was male at 60.26 %, while the age of most respondents was 45–64 years (43.59 %) and the most education was high school graduation at 38.47 %. The instrumental support variable is the variable that has the most influence on adherence to medication in MDR-TB patients with (Sig. &lt;0.005).</div></div><div><h3>Conclusion</h3><div>Social support from health workers influences adherence to medication in MDR-TB patients.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101890"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness comparison of patients with hepatitis C virus genotypes 1 or 4 therapies","authors":"Abdullah Althemery ,&nbsp;Abdulrahman Alturaiki ,&nbsp;Rawan Alanazi ,&nbsp;Nawal Almotairi ,&nbsp;Manal Aljohani ,&nbsp;Khalefa Althiab ,&nbsp;Abdullah Alfaifi","doi":"10.1016/j.cegh.2024.101880","DOIUrl":"10.1016/j.cegh.2024.101880","url":null,"abstract":"<div><h3>Background</h3><div>HCV is a global threat and can lead to major complications. The aim of this study was to compare the rate of achieving SVR12 from sofosbuvir-based therapy versus paritaprevir-based therapy in patients with HCV genotypes 1 or 4 in the Kingdom of Saudi Arabia.</div></div><div><h3>Methods</h3><div>This study was a retrospective cohort design conducted between January 2016 and January 2019; Participants were classified into sofosbuvir-based therapy (SBT) or paritaprevir-based therapy (PBT). Also, HCV specific genotype was examined: genotype 1, genotype 4, or mixed genotypes. A series of descriptive statistics were designed to compare patient characteristics. Significant predictors of SVR12 were identified using a stepwise logistic regression analysis.</div></div><div><h3>Results</h3><div>A total of 387 patients (294 on SBT; 93 on PBT) were included. The two groups were similar in most predisposing factors. 25.58 % of the overall sample reported previous treatment failure. Five predictors were identified that influence the achievement SVR12: sex, HCV type, interruption of therapy, alanine transaminase level, and hemoglobin level.</div></div><div><h3>Conclusions</h3><div>Saudi patients with HCV infection have a higher incidence of having genotype 4. In addition, both treatment regimens were associated with high percentages of attaining SVR at 12 weeks. More research is needed, particularly regarding the role of mixed genotypes in treatment outcomes.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101880"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between sleep quality and ischemic heart disease: Insights from a case-control study","authors":"Ghada O. Wassif,&nbsp;Shaimaa S. Yousef,&nbsp;Hebat Allah M.S. Gabal","doi":"10.1016/j.cegh.2024.101862","DOIUrl":"10.1016/j.cegh.2024.101862","url":null,"abstract":"<div><h3>Background</h3><div>Ischemic heart disease (IHD) significantly impacts global morbidity and mortality. Recent studies highlight a bidirectional relationship between cardiovascular health and sleep quality. This study investigates how IHD predicts poor sleep quality, emphasizing the need for integrated management of cardiovascular and sleep health. <strong>Methods</strong>: A case-control study was conducted at Ain Shams University Hospitals, Cairo, Egypt, involving 370 adults aged 40–75 years (185 cases, 185 controls). Data were collected using a standardized interview questionnaire covering socio-demographic data, IHD risk factors, and the Pittsburgh Sleep Quality Index (PSQI).</div></div><div><h3>Results</h3><div>Significant risk factors for IHD included smoking, elevated blood pressure, obesity, and family history. Differences in sleep quality dimensions were observed between cases and controls. IHD, age, gender, and BMI were significant predictors of PSQI. <strong>Conclusion &amp; Recommendation</strong>: The study underscores the significant association between IHD and poor sleep quality, highlighting the importance of considering sleep quality in managing IHD patients.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101862"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic disease burden and its associated risk factors among migrant workers in Saudi Arabia","authors":"Juliann Saquib ,&nbsp;Anwar Umar ,&nbsp;Idris Sula ,&nbsp;Abdulrahman Almazrou ,&nbsp;Yousuf Hafez Abdul Halim ,&nbsp;Muhammad Candragupta Jihwaprani ,&nbsp;Ahmed Assef Mousa ,&nbsp;Ahmed Emad Ali ,&nbsp;Momen Hassan Darwish ,&nbsp;Mohammed Najmi Alhaimi ,&nbsp;Ayman Alshoaibi ,&nbsp;Ayman Mohammed Yakout ,&nbsp;Mohammed Abdallah Shawat ,&nbsp;Nazmus Saquib","doi":"10.1016/j.cegh.2024.101889","DOIUrl":"10.1016/j.cegh.2024.101889","url":null,"abstract":"<div><h3>Background</h3><div>Few studies in Saudi Arabia have comprehensively assessed chronic conditions among migrant workers, although they make up one-third of the population. We aimed to assess the prevalence of chronic conditions (i.e., asthma, chronic obstructive pulmonary disease, diabetes, eczema, heart disease, hypertension, obesity, and peptic ulcers) and evaluate the associations between the chronic conditions and other factors (i.e., age, sex, occupation, nationality, and lifestyle) in a sample of migrant workers.</div></div><div><h3>Methods</h3><div>A cross-sectional study of 2123 migrant workers who represented seven occupation groups was conducted in Al-Qassim, Saudi Arabia. Chronic conditions were self-reported or assessed with physical/biological measurements or validated screening questionnaires. Covariates were assessed with standard questions. A multinomial logistic regression identified the significantly associated factors.</div></div><div><h3>Results</h3><div>The mean age of the participants was 35 ± 9 years; 85.3 % were men, and 65 % were from the Indian subcontinent. We found the following chronic condition prevalence estimates: hypertension = 28.4 %, obesity = 17 %, diabetes = 7.1 %, eczema = 5.7 %, peptic ulcer = 4.0 %, asthma = 2.1 %, chronic obstructive pulmonary disease = 0.9 %, and heart disease = 0.8 %. Nearly a third (31.3 %) of participants had one chronic condition, and 16 % had ≥2 chronic conditions. The factors significantly associated with having ≥2 chronic conditions were female gender (odds ratio [OR] 2.9, 95 % confidence interval [CI] 1.62–5.19), a university education (OR 2.4, 95 % CI 1.28–4.42), being a past smoker (OR 4.2, 95 % CI 2.26–7.83), and inactivity (OR 2.4, 95 % CI 1.46–3.84).</div></div><div><h3>Conclusion</h3><div>A significant portion of migrant workers in Saudi Arabia are afflicted with chronic conditions.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101889"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the landscape of the 1918 influenza and the 2019 coronavirus pandemics in mapping potential sentinel surveillance sites for emerging and re-emerging infectious diseases in Ghana","authors":"Peter N-jonaam Mahama ,&nbsp;Amos Tiereyangn Kabo-bah ,&nbsp;Samuel Fosu Gyasi ,&nbsp;Prince Antwi-Agyei ,&nbsp;Edmund Ilimoan Yamba ,&nbsp;Justin Yieri","doi":"10.1016/j.cegh.2024.101901","DOIUrl":"10.1016/j.cegh.2024.101901","url":null,"abstract":"<div><h3>Background/objectives</h3><div>Ghana, a major travel hub in West Africa, faces a high risk of infectious disease transmission due to frequent travel and cross-border movement. The 2019 coronavirus pandemic, like the 1918 influenza pandemic, highlighted gaps in infectious disease surveillance and outbreak response systems. This study aimed to assess how Ghana can better monitor and respond to emerging and re-emerging infectious diseases (ERIDs) by evaluating its existing surveillance infrastructure.</div></div><div><h3>Method</h3><div>Focusing on Influenza-Like Illness (ILI) and Severe Acute Respiratory Infections (SARI) - key targets for pandemic surveillance - the study analysed the diffusion patterns of the 1918 influenza and 2019 coronavirus in Ghana. Existing surveillance sites were reviewed to identify potential new sites for optimal sentinel surveillance.</div></div><div><h3>Results</h3><div>The first month of the 1918 influenza and 2019 coronavirus outbreaks in Ghana covered 31.8 % and 22.2 % of districts, with full-country spread taking 15 and 13 weeks respectively. The analysis further revealed that towns, villages, and socio-economic routes, particularly in the middle belt and Accra, were high-risk areas. Based on the findings, an additional 369 primary, 610 secondary, and 3176 tertiary surveillance sites were proposed to supplement the current 31 ILI and SARI sites.</div></div><div><h3>Conclusion</h3><div>Expanding the current surveillance system to include ERIDs will enhance Ghana's capacity to efficiently monitor and respond to future outbreaks, improving health security in resource-limited settings.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101901"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal marriage distance does not affect sickle haemoglobin status: A study from tribal population of Rajasthan","authors":"P.K. Anand ,&nbsp;Hitesh Tiwari ,&nbsp;P.K. Dam ,&nbsp;S.S. Mohanty ,&nbsp;Chetram Meena","doi":"10.1016/j.cegh.2024.101902","DOIUrl":"10.1016/j.cegh.2024.101902","url":null,"abstract":"","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101902"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of adherence to antiretroviral therapy and its related factors among people living with HIV in the region of Beni-Mellal-Khenifra, Morocco","authors":"Benaddi Mina ,&nbsp;Sabour Alaoui Sanaa ,&nbsp;Benksim Abdelhafid","doi":"10.1016/j.cegh.2024.101872","DOIUrl":"10.1016/j.cegh.2024.101872","url":null,"abstract":"<div><h3>Background</h3><div>The management of the human immunodeficiency virus (HIV) as a chronic infection involves an optimal adherence to antiretroviral therapy (ART), which is determined by several factors as currently mentioned in the literature. This study aimed to describe the adherence to antiretroviral therapy among people living with HIV (PLHIV) and its related factors in the region of Beni-Mellal-Khenifra.</div></div><div><h3>Materials and methods</h3><div>A cross-sectional study was conducted on 160 PLHIV and attending the regional hospital of Beni-Mellal, Morocco between February and July 2022. Participants were collected using a non-probabilistic sampling. The adherence to ART was assessed using the simplified medication adherence questionnaire (SMAQ). The sociodemographic and clinical characteristics of the participants were collected through an interviewer-administered questionnaire and consultation of medical records. Binominal logistic regression was used to determine potential factors influencing the adherence to ART. Statistical significance was set at p &lt; 0.05.</div></div><div><h3>Results</h3><div>the adherence rate to ART among PLHIV was of 73.1 %. The data analysis revealed the associated factors to antiretroviral therapy to be: therapeutic patient education (OR = 0.217; 95%CI [0.049–0.955]), treatment regimen (OR = 0.155; 95%CI [0.026–0.923]), and viral load (OR = 0.43; 95%CI = [0.007–0.284]).</div></div><div><h3>Conclusion</h3><div>the health strategies should focus on therapeutic patient education programs, and encourage drug industry to minimize the complexity of ART regimens.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101872"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}