Clinical Epidemiology and Global Health最新文献

{"title":"Letter to the Editor: “A study on socio-demographic-based knowledge and awareness for cervical cancer among women from Uttar Pradesh, India”","authors":"Kushal Krishna Banerjee, Rabia Batool Hussain","doi":"10.1016/j.cegh.2024.101891","DOIUrl":"10.1016/j.cegh.2024.101891","url":null,"abstract":"","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101891"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of prurigo nodularis: An analysis of global trends from 1998–2023","authors":"Shiyan Yang , Chunxiao Wang , Sihan Wang , Yuanting Yu , Xiaoce Cai , Yifei Wang , Xin Li","doi":"10.1016/j.cegh.2024.101906","DOIUrl":"10.1016/j.cegh.2024.101906","url":null,"abstract":"","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101906"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ten-year Atherosclerosis Cardiovascular Disease (ASCVD) risk score and its components among nomadic population in southern Iran: A population-based study","authors":"Fariba Moradi Ardekani ,&nbsp;Mohammad Javad Zibaeenezhad ,&nbsp;Mehrab Sayadi ,&nbsp;Fatemeh Jafari ,&nbsp;Shirzad Javidi AL-e-Saadi ,&nbsp;Hamed Karami ,&nbsp;Aboubakr Jafarnezhad ,&nbsp;Sina Rokhsari ,&nbsp;Ahad Amiri Gharghani","doi":"10.1016/j.cegh.2025.101913","DOIUrl":"10.1016/j.cegh.2025.101913","url":null,"abstract":"<div><h3>Introduction</h3><div>Prevalence of atherosclerotic cardiovascular disease (ASCVD) has increased in developing countries, such as Iran. For reducing ASCVD, epidemiological information, especially in nomadic populations, are needed. This study aimed to estimate the prevalence of ASCVD among the nomadic population.</div></div><div><h3>Method</h3><div>This cross-sectional study was conducted on 784 nomadic people aged 40–70 years in Fars province. The 10-year ASCVD risk was calculated with an estimator developed by the American College of Cardiology/American Heart Association (ACC/AHA). To determine the factors of ASCVD risk score, ordinal logistic regression was used. Statistical analyses were performed using SPSS version 16 software.</div></div><div><h3>Results</h3><div>The mean age of the subjects under study was 53.32 ± 8.94 years, of whom 432 (55.1 %) were female. Based on ordinal regression, access to the health centers (p = 0.002), diabetes (p &lt; 0.001), MI (p = 0.023), not using Aspirin (p = 0.001), housekeeper job (p &lt; 0.001), high LDL (p = 0.002), and physical activity (p = 0.04) were associated with a higher category of ASCVD risk score. Additionally, people in the age group of 60–69 years had the highest percentage in all ASCVD score classes except the low-risk group.</div></div><div><h3>Conclusion</h3><div>The results indicated that having modifiable risk factors increases the chance of CVD in the nomadic population, and older people are more at risk. Since this population has received less attention and plays a main role in providing food products for Iranian people, it is suggested that more attention should be paid to the health of this special group through prevention and control programs.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101913"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and factors associated with cognitive impairment among persons with type 2 diabetes mellitus: A cross-sectional study in medical college hospitals of South India","authors":"Pracheth Raghuveer ,&nbsp;Manaal Shamsudeen ,&nbsp;Shipra Sridhar ,&nbsp;Riya Singla ,&nbsp;Vaibhav Gupta ,&nbsp;Namit Mittal ,&nbsp;Diva Bhandari ,&nbsp;Mithun Rao","doi":"10.1016/j.cegh.2024.101887","DOIUrl":"10.1016/j.cegh.2024.101887","url":null,"abstract":"<div><h3>Background</h3><div>The increased prevalence of diabetes is of a major concern in the background of a developing country like India with tremendous population. Diabetes Mellitus type 2 leads to complications if not diagnosed early and started on treatment. Adding to this, persons with Type 2 Diabetes Mellitus (T2DM) are also vulnerable to develop cognitive impairment and affects many cognitive domains. Therefore, recognition of cognitive disorders among diabetic persons with T2DM are important.</div></div><div><h3>Method</h3><div>ology: This is a cross sectional study done in persons with T2DM attending two tertiary care teaching hospitals. There were a total of 108 study participants aged ≥18 years and the study was done for one month. Cognitive screening was carried out using Montreal Cognitive Assessment (MoCA) and a score of ≥26 out of 30 was considered as normal cognitive function.</div></div><div><h3>Results</h3><div>It was observed that 45 (41.70 %) of the participants had cognitive impairment and it was found to be higher among persons aged ≥60 years, 27 (75.0 %) when compared to age &lt;60 years, 36 (50.0 %). This association was found to be statistically significant (p = 0.02). Of the 58 participants who had diabetes for &gt;7years, 41 (70.70 %), had cognitive impairment while 17 (29.30 %) did not have (p &lt; 0.01). Cognitive impairment was found to be significantly higher among participants with hypertension (74.20 %) when compared to those without hypertension (59.70 %).</div></div><div><h3>Conclusion</h3><div>Prevalence of cognitive impairment in persons with T2DM was found out to be 58.30 %. Duration of diabetes ≥7 years was found to be the significant factor associated with cognitive impairment in our research.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101887"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vision-related Quality of Life (VRQOL) and its determinants among the Elderly in rural blocks of Haryana, India","authors":"Mona Duggal ,&nbsp;Ankita Kankaria ,&nbsp;Latika Rohilla ,&nbsp;Harashish Jindal ,&nbsp;Limalemla Jamir ,&nbsp;Parul Chawla Gupta ,&nbsp;Debarati Sarkar ,&nbsp;Vaibhav Miglani ,&nbsp;Akash Kumar ,&nbsp;Drishti Sharma ,&nbsp;Neha Dahiya ,&nbsp;Siddhartha Sharma ,&nbsp;Sandeep Grover","doi":"10.1016/j.cegh.2024.101865","DOIUrl":"10.1016/j.cegh.2024.101865","url":null,"abstract":"<div><h3>Background</h3><div>Vision related quality of life (VRQOL) measures one's satisfaction with their visual ability to perform daily activities. Aging leads to vision impairment that can negatively affect VRQOL and physical, psychological, and social well-being.</div></div><div><h3>Objective</h3><div>To assess vision-related quality of life (VR-QOL) and its determinants among elderly residents from rural blocks of Haryana, India.</div></div><div><h3>Method</h3><div>This cross-sectional study was performed across 52 Indian villages. The vision-related quality of life scores was assessed using National Eye Institute Vision Function Questionnaire-25(VFQ-25). Social Connectedness, Geriatric Depression Scale, Mini-Mental Status Examination, and the Katz Index of Independence were collected using validated tools. Continuous data was represented as Mean (±SD) or median (IQR) depending upon their distribution. Categorical data as frequency (%). Bivariate analysis was done using Student t-test or Rank Sum test for continuous variables (for up to 2 groups) and One-Way ANOVA was run for continuous variables (for more than 2 groups). Chi-Sq. test or Fisher's for categorical variables and multivariable linear regression model was run to calculate the determinants of the VFQ composite score.</div></div><div><h3>Result</h3><div>Amongst the 420 participants, 58 % were females and 74 % were illiterates. The mean VR-QOL was 42.30 ± 11.19 in the study population. The study found higher VR-QOL scores in <em>General Health, Distance activities,</em> and <em>Near activities</em>, while lower scores were observed in <em>Mental health, Dependency, Social functioning, Ocular pain, General vision</em>, and <em>Role difficulties</em>. Both the mean VR-QOL composite score and the VR-QOL domains of <em>General Health, General Vision, Ocular Pain, Role Difficulties, Mental Health,</em> and <em>Dependence</em> were all greater for women than for men. Among the reported morbidities 26 % had hearing loss, 23 % were hypertensives, 9 % were diabetics, 85 % were dependent, 60 % had depression, 14 % had moderate dementia, 10 % had lower tendency to connect, 8 % had low vision and 35 % had vertigo. VFQ scores were lower among males, non-Hindus, hypertensives and among person with history of vertigo and those living in dim light than their counterparts.</div></div><div><h3>Conclusion</h3><div>The current study shows that VR-QOL is significantly lower in male, participants with history of vertigo, hypertension, diabetes and who live in dim light. There is a need to develop strategies to address these determinants through multidisciplinary approach including chronic disease management and environmental modification and promote healthy aging of elderly population.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101865"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of bronchial asthma among urban school children in Bengaluru city","authors":"Giriyanna Gowda ,&nbsp;Sweta Balappa Athani ,&nbsp;Sunil Maragowdanahalli Gurupadaswamy","doi":"10.1016/j.cegh.2024.101895","DOIUrl":"10.1016/j.cegh.2024.101895","url":null,"abstract":"<div><h3>Background</h3><div>Bronchial asthma, with its increasing prevalence in both developed and developing countries, is a global health problem. It causes sleep disorders, impedes growth, disrupts education, increases the socioeconomic burden and hence lowers the quality of life of the affected individuals, their family and society at large. Children in urban areas, being a highly affected group, require special attention. Hence, the present study was conducted with the objectives below:1. To determine the prevalence of Bronchial asthma among urban school children.2. To identify the risk factors associated with bronchial asthma.</div></div><div><h3>Methods</h3><div>Schools were randomly selected after enlisting all schools in 2 wards of BBMP-South and permissions were obtained. Sampling frame consists of cumulative population of all school children. The sample size was calculated to be 1140. List of children aged between 10 and 15 years was prepared from the attendance register from each school and children were selected from the list using systematic random sampling. Each consenting student was interviewed using pretested semi structured questionnaire developed using ISAAC (International study on Asthma and Allergies in Childhood) module. Data was entered and analyzed using Epi-Info 7.2.2.1.</div></div><div><h3>Results</h3><div>A total of 1140 children were interviewed, of which 541(47.5 %) were females and 599(52.5 %) were males. The mean age was 12.57 ± 1.61years. The prevalence of asthma was 5.79 %. A family history of allergic disorders and history of preterm birth were significantly associated with Bronchial Asthma (p &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>Asthma is a major health problem among urban school children.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101895"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating public perception, knowledge and phobia towards corticosteroids post COVID-19: A cross-sectional study in India","authors":"Sushma Surendra Patkar ,&nbsp;Manasmitha R. Shettigar ,&nbsp;Nithesh Malathesh Gujjar ,&nbsp;Mohamed Hassan Elnaem ,&nbsp;Muna Barakat ,&nbsp;Mohammed Salim Karattuthodi","doi":"10.1016/j.cegh.2024.101881","DOIUrl":"10.1016/j.cegh.2024.101881","url":null,"abstract":"<div><h3>Introduction</h3><div>Corticosteroids (CS) have been used to treat various inflammatory and allergy disorders for over a few decades. Though the effectiveness of CS is proven, safety concern prevails. The public is now more aware of CS because of the COVID-19 pandemic, but their information sources still need verification. The study investigates the general public's knowledge, experience, and fears about CS, examining their acceptance and validity, and their relationship with factors like gender, age, and education.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted among the general public of India for six months. An online questionnaire was utilized to collect the perception, knowledge, and phobia towards CS following COVID-19. People who could read and understand English were included in the study. Age, gender, education level, and prior corticosteroid use were tested as predictors for knowledge and corticophobia scores by linear regression.</div></div><div><h3>Results</h3><div>A study involving 472 participants, primarily females and university students, found that less than 32 % were previously infected with COVID-19 and 33 % had used CS for respiratory and dermatological disorders. A quarter of the samples experienced acne and mood changes. The population had a satisfactory knowledge score, but a high phobia score. Corticophobia score was positively associated with side effects and knowledge score, but educational level negatively influenced the development of corticophobia.</div></div><div><h3>Conclusion</h3><div>The study found that, despite having a satisfactory knowledge of CS, participants displayed a high corticophobia score. Addressing this issue requires awareness campaigns, patient education programs, and patient interaction, and educating healthcare workers.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101881"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unravelling prevalence of metabolic syndrome in Baiga tribe of Dindori district of central India","authors":"Suyesh Shrivastava ,&nbsp;Kritika Singh ,&nbsp;Arvind Kavishwar ,&nbsp;Teena Kashyap ,&nbsp;Vandana Golhani ,&nbsp;Santosh Patkar ,&nbsp;Harpreet Kaur ,&nbsp;Tapas Chakma","doi":"10.1016/j.cegh.2024.101868","DOIUrl":"10.1016/j.cegh.2024.101868","url":null,"abstract":"<div><h3>Introduction</h3><div>Metabolic syndrome is the co-occurrence of abnormalities that can ultimately increase the risk of cardiovascular diseases in a particular individual. The abnormalities include hypertension, hyperglycemia, dyslipidemia, and obesity. As the tribal population is now living a transitioning lifestyle, they are also becoming susceptible to various key factors responsible for the metabolic syndrome. The study of the prevalence of metabolic syndrome in the tribal population is a necessary step to know its true status.</div></div><div><h3>Aim &amp; objective of the study</h3><div>To estimate the prevalence of metabolic syndrome among adults of Baiga tribe population of Dindori district of Madhya Pradesh.</div></div><div><h3>Methodology</h3><div>The present study is a cross-sectional study, in which 791 respondents from the Baiga tribe of Dindori district, Madhya Pradesh, India screened for metabolic syndrome. The villages were selected by cluster sampling and the respondents by simple random sampling from age 18 years–65 years. The respondents were subjected to WHO STEP-wise approach to the NCD risk factor surveillance questionnaire for socio-demographic, behavioral, physical activity, and clinical measurements. Subsequently, anthropometric measurements were done and blood &amp; urine samples were collected for the biochemical tests. The dietary patterns were recorded by a self-designed, catering tribal diets food frequency questionnaire. The criteria used for determination were given by the National Cholesterol Education Program, Adult Treatment Panel III (NCEP ATP III).</div></div><div><h3>Results &amp; analysis</h3><div>According to NCEP ATP III criteria, the prevalence of metabolic syndrome in the Baiga tribe of Dindori district was observed to be 7.83 %, in which males accounted for 6.9 % and females for 9.2 %.</div></div><div><h3>Discussions</h3><div>The present study shows a high prevalence of metabolic syndrome among the tribal population. This can be inferred as the situation in the tribal population is as serious as it is in the urban population. The situation can become more complicated as the tribal population lives in remote and secluded areas and has poor diagnostic and treatment facilities as compared to the urban population. Thus, immediate attention is required from the tribal health policymakers to intervene in this matter.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101868"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of the Snehita BRISK model: A breast cancer risk assessment tool for risk stratification in women of the Indian subcontinent","authors":"Regi Jose ,&nbsp;Paul Augustine ,&nbsp;Lizbeth Paul ,&nbsp;Jeesha C. Haran ,&nbsp;Sujha Subramanian","doi":"10.1016/j.cegh.2024.101884","DOIUrl":"10.1016/j.cegh.2024.101884","url":null,"abstract":"<div><h3>Background</h3><div>Breast cancer is the most prevalent cancer among women globally and in India, with rising incidence rates, particularly among younger women. Early detection remains crucial for reducing mortality. Risk assessment may motivate women to undergo examinations and utilize the calculator for risk stratification in early detection programs. However, existing breast cancer risk prediction models, primarily developed in Western populations, may not be fully applicable to the Indian context due to demographic, lifestyle, and genetic differences. This study aims to develop and validate the Snehita BRISK model, a logistic regression-based risk prediction tool tailored to the Indian subcontinent.</div></div><div><h3>Methods</h3><div>A case-control study involving 660 cases and 910 controls was conducted. Data were collected through structured interviews covering socio-demographic details, reproductive history, prior breast biopsies, and family history of breast cancer. Logistic regression analysis was employed to identify significant risk factors of breast cancer, leading to the formulation of the Snehita BRISK model. The model's performance was evaluated using Receiver Operating Characteristic (ROC) analysis, with additional validation tests.</div></div><div><h3>Results</h3><div>Significant risk factors included advancing age, early age at menarche, late age at first childbirth, nulliparity, irregular menstrual cycles, family history of breast cancer, and history of previous breast biopsies. The Snehita BRISK model demonstrated strong predictive accuracy (67.3 %) with an overall Area Under the Curve (AUC) of 0.699, sensitivity of 45.6 %, and specificity of 83 %. The model showed particularly high predictive accuracy (71.1 %) in women aged 50 years or older (AUC = 0.750). The overall probability cut-off for identifying high-risk women was 0.4338.</div></div><div><h3>Conclusion</h3><div>The Snehita BRISK model is a promising tool for breast cancer risk assessment, specifically tailored for women in the Indian subcontinent. By identifying high-risk women and motivating them to undergo timely examinations, this model supports effective risk stratification in screening programs and enhances early detection efforts. Presented as the ‘Snehita Breast Cancer Risk Calculator,’ this tool aims to elevate early detection rates, particularly among older women. However, further validation in independent populations is necessary to confirm its broader applicability and effectiveness across diverse groups.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101884"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and burden of osteoarthritis amongst older people in Colombia: Results from national survey of health, wellbeing, and aging (SABE Colombia)","authors":"Fernando Gomez ,&nbsp;Gustavo Duque ,&nbsp;Carmen-Lucia Curcio ,&nbsp;Laura Cano ,&nbsp;David Osorio ,&nbsp;Sebastian Rios","doi":"10.1016/j.cegh.2024.101829","DOIUrl":"10.1016/j.cegh.2024.101829","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the prevalence of osteoarthritis (OA) and to identify factors related with person-level risk factors among older people in Colombia.</div></div><div><h3>Study design</h3><div>This study used cross-sectional data from 23.694 adults aged ≥60 or older (median: 70.8 years, 57.3 % women) living in rural and urban communities from the National Survey of Health, Wellbeing and Aging in Colombia (SABE Colombia, according to its initials in Spanish).</div></div><div><h3>Methods</h3><div>Logistic regression was used to determine associations between the presence of OA and a range of sociodemographic, health-related, functional, biomarkers, and social/environmental variables.</div></div><div><h3>Results</h3><div>The overall prevalence of OA was 26 % (women-36.5 %; men-14.9 %). Prevalence increased with age and in mestizo ethnicity placed in urban areas. On multivariable analysis, OA was significantly associated with older age, female gender, multimorbidity, fair/poor self-perceived health, a higher body mass index (BMI), a greater number of physical limitations, and perceived safety/security problems in the neighborhood. In particular, there was a strong association between multimorbidity and the presence of OA (OR = 4.97 (95 % CI 4.46, 5.53)). An inverse association between HDL cholesterol levels and the prevalence of OA was observed. Triglyceride levels showed a significant trend.</div></div><div><h3>Conclusions</h3><div>OA is a common and multifaceted condition, with a comparable prevalence of self-reported OA in Colombia with similar populations elsewhere. Assessment and management should focus on potentially modifiable factors such as BMI, multimorbidity, metabolic syndrome, physical limitations, mobility disabilities, and safety/security problems in the neighborhoods. More research is required to understand the complex interrelationships between these and other risk-associated variables.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101829"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}