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Printing in Time for Cranio-Maxillo-Facial Trauma Surgery: Key Parameters to Factor in. 颅颌面创伤手术的及时打印:需要考虑的关键参数。
IF 0.9 Pub Date : 2023-06-01 Epub Date: 2022-04-20 DOI: 10.1177/19433875221083231
Léonard Bergeron, Michelle Bonapace-Potvin, François Bergeron

Study design: retrospective cohort study.

Objective: 3D printing is used extensively in cranio-maxillo-facial (CMF) surgery, but difficulties remain for surgeons to implement it in an acute trauma setting because critical information is often omitted from reports. Therefore, we developed an in-house printing pipeline for a variety of cranio-maxillo-facial fractures and characterized each step required to print a model in time for surgery.

Methods: All consecutive patients requiring in-house 3D printed models in a level 1 trauma center for acute trauma surgery between March and November 2019 were identified and analyzed.

Results: Sixteen patients requiring the printing of 25 in-house models were identified. Virtual Surgical Planning time ranged from 0h 08min to 4h 41min (mean = 1h 46min). The overall printing phase per model (pre-processing, printing, and post-processing) ranged from 2h 54min to 27h 24min (mean = 9h 19min). The overall success rate of prints was 84%. Filament cost was between $0.20 and $5.00 per model (mean = $1.56).

Conclusions: This study demonstrates that in-house 3D printing can be done reliably in a relatively short period of time, therefore allowing 3D printing usage for acute facial fracture treatment. When compared to outsourcing, in-house printing shortens the process by avoiding shipping delays and by having a better control over the printing process. For time-critical prints, other time-consuming steps need to be considered, such as virtual planning, pre-processing of 3D files, post-processing of prints, and print failure rate.

研究设计:回顾性队列研究.目的:3D打印技术在颅颌面(CMF)手术中得到了广泛应用,但外科医生在急性创伤环境中实施该技术仍存在困难,因为报告中经常遗漏关键信息。因此,我们为各种颅颌面骨折开发了内部打印流水线,并描述了及时打印出手术模型所需的每个步骤:确定并分析了2019年3月至11月期间在一级创伤中心进行急性创伤手术时需要内部3D打印模型的所有连续患者:结果:确定了需要打印 25 个内部模型的 16 名患者。虚拟手术规划时间从 0 小时 08 分钟到 4 小时 41 分钟不等(平均 = 1 小时 46 分钟)。每个模型的整体打印阶段(预处理、打印和后处理)从 2 小时 54 分钟到 27 小时 24 分钟不等(平均 = 9 小时 19 分钟)。整体打印成功率为 84%。每个模型的灯丝成本在 0.20 美元到 5.00 美元之间(平均 = 1.56 美元):本研究表明,内部三维打印可在相对较短的时间内可靠完成,因此可将三维打印用于急性面部骨折治疗。与外包相比,内部打印可避免运输延误,并能更好地控制打印过程,从而缩短流程。对于时间紧迫的打印,还需要考虑其他耗时的步骤,如虚拟规划、三维文件预处理、打印后处理和打印失败率。
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引用次数: 0
Patterns and Trends of Facial Fractures at a Tertiary Care Trauma Center in India - A 13 years Retrospective Study. 印度一家三级医疗创伤中心面部骨折的模式和趋势--13 年回顾性研究。
IF 0.9 Pub Date : 2023-06-01 Epub Date: 2022-04-19 DOI: 10.1177/19433875221084172
Debraj Shome, Monika Surana, Shiva Ram Male, Vaibhav Kumar, Supriya S Vyavahare, Arundha Abrol, Rinky Kapoor

Study design: Retrospective study.

Objective: The purpose of this study was to retrospectively analyze the prevalence, pattern, diagnosis, and treatment of the facial fractures falling under ambit of facial plastic surgery in a multi-specialty hospital at India from the year 2006-2019.

Methods: This retrospective study analyzed 1508 patients, having orbital fractures (from 2006 to 2019) for demographic data, cause of trauma, type of fracture, and the treatment given. The data were compiled in excel and analyzed by using SPSS version 21.0.

Results: Out of these 1508 patient (1127 (74.73%)-males and 381 (25.27%)-females), the etiology of injuries was Road traffic accident (RTA) (49.20%), assault (26.52%), and sports injuries (11.47%). The most common fracture pattern was Isolated Orbit and/or Orbital Floor fracture in 451 patients (32.08%), followed by Mid-facial fractures (21.93%). Also, 105 patients (6.96%) experienced ocular/retinal trauma along with other fractures.

Conclusions: Orbit, peri-ocular, and mid-face trauma comprised a large position of this study. It requires a great deal of expertise to treat such complex trauma, which is not covered in one specialty alone. Hence, a holistic approach of craniofacial fracture management, rather than limiting these skills to water-tight craniofacial compartments becomes necessary. The study highlights the critical need of multidisciplinary approach for predictable and successful management of such complex cases.

研究设计回顾性研究:本研究旨在回顾性分析2006-2019年印度一家多专科医院面部整形外科范围内面部骨折的患病率、模式、诊断和治疗情况:这项回顾性研究分析了 1508 名眼眶骨折患者(2006 年至 2019 年)的人口统计学数据、外伤原因、骨折类型和治疗方法。数据以 excel 格式编制,并使用 SPSS 21.0 版进行分析:在这 1508 名患者中(男性 1127 人(74.73%),女性 381 人(25.27%)),受伤病因为道路交通事故(RTA)(49.20%)、袭击(26.52%)和运动损伤(11.47%)。最常见的骨折类型是孤立性眼眶和/或眶底骨折,共有 451 名患者(32.08%),其次是面中部骨折(21.93%)。此外,有 105 名患者(6.96%)在发生其他骨折的同时还伴有眼部/视网膜创伤:本研究中,眼眶、眼周和面中部创伤占很大比例。治疗这种复杂的外伤需要大量的专业知识,而这不是一个专业就能完成的。因此,有必要对颅面骨折进行整体处理,而不是将这些技能局限于颅面部位。该研究强调了多学科方法对于可预测和成功处理此类复杂病例的关键必要性。
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引用次数: 0
Editorial. 社论
IF 0.9 Pub Date : 2023-06-01 Epub Date: 2023-04-08 DOI: 10.1177/19433875231167030
Sat Parmar, Rui Fernandes
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引用次数: 0
Treatment of Persistent Post-traumatic Diplopia - An Algorithmic Approach to Patient Stratification and Operative Management. 外伤后持续性复视的治疗--患者分层和手术治疗的算法方法。
IF 0.9 Pub Date : 2023-06-01 Epub Date: 2022-03-26 DOI: 10.1177/19433875221083084
Sashank K Reddy, Salih Colakoglu, Joshua S Yoon, Myan Bhoopalam, Shannath L Merbs, Paul N Manson, Michael P Grant

Study design: Retrospective chart review of revisional orbital surgery outcomes in patients with diplopia from prior operative treatment of orbital trauma.

Objective: Our study seeks to review our experience with management of persistent post-traumatic diplopia in patients with previous orbital reconstruction and present a novel patient stratification algorithm predictive of improved outcomes.

Methods: A retrospective chart review was performed on adult patients at Wilmer Eye Institute at Johns Hopkins Hospital and at the University of Maryland Medical Center who underwent revisional orbital surgery for correction of diplopia for the years 2005-2020. Restrictive strabismus was determined by Lancaster red-green testing coupled with computed tomography and/or forced duction. Globe position was assessed by computed tomography. Seventeen patients requiring operative intervention according to study criteria were identified.

Results: Globe malposition affected fourteen patients and restrictive strabismus affected eleven patients. In this select group, improvement in diplopia occurred in 85.7% of cases with globe malposition and in 90.1% of cases with restrictive strabismus. One patient underwent additional strabismus surgery subsequent to orbital repair.

Conclusions: Post-traumatic diplopia in patients with prior orbital reconstruction can be successfully managed in appropriate patients with a high degree of success. Indications for surgical management include (1) globe malposition and (2) restrictive strabismus. High resolution computer tomography and Lancaster red-green testing discriminate these from other causes that are unlikely to benefit from orbital surgery.

研究设计:对曾接受眼眶外伤手术治疗而复视的患者进行眼眶再造手术结果的回顾性病历审查:我们的研究旨在回顾我们在处理曾接受过眼眶重建手术的复视患者的创伤后持续复视方面的经验,并提出一种新的患者分层算法,以预测更好的治疗效果:我们对约翰霍普金斯医院威尔默眼科研究所(Wilmer Eye Institute)和马里兰大学医学中心(University of Maryland Medical Center)2005-2020年间接受复视矫正眼眶手术的成年患者进行了回顾性病历审查。限制性斜视是通过兰卡斯特红-绿测试、计算机断层扫描和/或强迫抽吸来确定的。眼球位置通过计算机断层扫描进行评估。根据研究标准,确定了17名需要手术干预的患者:结果:14 名患者的眼球位置不正,11 名患者的局限性斜视。在这组选定的患者中,85.7%的球状体位置不正患者复视有所改善,90.1%的限制性斜视患者复视有所改善。一名患者在眼眶修复术后又接受了斜视手术:结论:对于曾接受过眼眶重建手术的患者来说,外伤后复视的治疗成功率很高。手术治疗的适应症包括:(1)眼球位置不正;(2)局限性斜视。高分辨率计算机断层扫描和兰卡斯特红-绿测试可将这些病因与其他不太可能从眼眶手术中获益的病因区分开来。
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引用次数: 0
Nine Years of Retrospective Study of Mandibular Fractures in Semi-urban Teaching Hospital, Shimla, Himachal Pradesh, India. 印度喜马偕尔邦西姆拉半城市教学医院下颌骨骨折九年回顾性研究。
IF 0.9 Pub Date : 2023-06-01 Epub Date: 2022-05-03 DOI: 10.1177/19433875221095984
Narotam K Ghezta, Yogesh Bhardwaj, Rangila Ram, Monika Parmar, Rowena N Basi, Pooja Thakur

Study design: Retrospective study.

Objective: To evaluate current trends in maxillofacial trauma, a retrospective study of mandibular fractures at Government Dental College and Hospital Shimla H.P was carried out.

Methods: In this retrospective study, records of 910 patients with mandibular fractures were reviewed between 2007 and 2015 in the Department of Oral and Maxillofacial Surgery out of total 1656 facial fractures. These mandibular fractures were assessed according to age, sex, aetiology in addition to monthly and yearly distribution. Post-operative complications such as malocclusion, neurosensory disturbances and infection were recorded.

Results: It was observed that mandibular fractures were most frequent in males (67.5%) and in the age group of 21-30 years; accidental fall was the most common etiological factor (43.8%) in the present study and in stark difference to already published reports. The most common fracture site was that of condylar region 239 (26.2%). Open reduction and internal fixation (ORIF) were done in 67.3% cases whereas 32.6% were managed by maxillomandibular fixation and circummandibular wiring. Miniplate osteosynthesis was the most favoured technique. The complication with ORIF was 16%.

Conclusions: To treat mandibular fractures, currently there are many techniques. However, in minimizing complications and in achieving satisfactory functional and aesthetic results experienced surgical team plays an important role.

研究设计回顾性研究:为了评估颌面部创伤的当前趋势,对希姆莱政府牙科学院和医院的下颌骨骨折进行了回顾性研究:在这项回顾性研究中,口腔颌面外科回顾了 2007 年至 2015 年间 910 名下颌骨骨折患者的记录,其中面部骨折患者总数为 1656 人。根据年龄、性别、病因以及每月和每年的分布情况对这些下颌骨骨折进行了评估。此外,还记录了术后并发症,如咬合不正、神经感觉障碍和感染等:本研究发现,下颌骨骨折最常见于男性(67.5%)和 21-30 岁年龄组;意外摔倒是最常见的病因(43.8%),这与已发表的报告截然不同。最常见的骨折部位是髁突区 239 处(26.2%)。67.3%的病例采用了切开复位内固定术(ORIF),32.6%的病例采用了上颌骨固定术和颌周布线术。最常用的技术是微板骨合成术。ORIF的并发症发生率为16%:结论:目前治疗下颌骨骨折有多种技术。结论:目前,治疗下颌骨骨折的技术有很多,但在减少并发症、获得满意的功能和美观效果方面,经验丰富的手术团队发挥着重要作用。
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引用次数: 0
Plastic and Maxillofacial Training for War-Zones - A Systematic Review. 战区整形和颌面培训 - 系统回顾。
IF 0.9 Pub Date : 2023-06-01 Epub Date: 2022-05-02 DOI: 10.1177/19433875221083416
Tiffanie-Marie Borg, Naveen Cavale, Ghassan Abu-Sittah, Ali Ghanem

Study design: Injuries sustained in war-zones are variable and constantly developing according to the nature of the ongoing conflict. Soft tissue involvement of the extremities, head and neck often necessitates reconstructive expertise. However, current training to manage injuries in such settings is heterogenous. This study involves a systematic review.

Objective: To evaluate interventions in place to train Plastic and Maxillofacial surgeons for war-zone environments so that limitations to current training can be addressed.

Methods: A literature search of Medline and EMBase was performed using terms relevant to Plastic and Maxillofacial surgery training and war-zone environments. Articles that met the inclusion criteria were scored then educational interventions described in included literature were categorised according to their length, delivery style and training environment. Between-group ANOVA was performed to compare training strategies.

Results: 2055 citations were identified through this literature search. Thirty-three studies were included in this analysis. The highest scoring interventions were over an extended time-frame with an action-oriented training approach, using simulation or actual patients. Core competencies addressed by these strategies included technical and non-technical skills necessary when working in war-zone type settings.

Conclusions: Surgical rotations in trauma centers and areas of civil strife, together with didactic courses are valuable strategies to train surgeons for war-zones. These opportunities must be readily available globally and be targeted to the surgical needs of the local population, anticipating the types of combat injuries that often occur in these environments.

研究设计:战区的受伤情况各不相同,并根据持续冲突的性质不断变化。四肢、头部和颈部的软组织损伤往往需要专业的整形技术。然而,目前在这种环境下处理创伤的培训各不相同。本研究是一项系统性综述:评估针对战区环境培训整形颌面外科医生的干预措施,以解决当前培训的局限性:方法:使用与整形和颌面外科医生培训及战区环境相关的术语对 Medline 和 EMBase 进行文献检索。对符合纳入标准的文章进行评分,然后根据篇幅、授课方式和培训环境对纳入文献中描述的教育干预措施进行分类。进行组间方差分析以比较培训策略。本次分析共纳入 33 项研究。得分最高的干预措施是在较长的时间范围内,采用行动导向的培训方法,使用模拟或实际病人。这些策略涉及的核心能力包括在战区环境中工作所需的技术和非技术技能:结论:在创伤中心和内乱地区进行外科轮转以及开设教学课程是培训战区外科医生的重要策略。这些机会必须在全球范围内随时提供,并以当地人口的外科需求为目标,预测在这些环境中经常出现的战伤类型。
{"title":"Plastic and Maxillofacial Training for War-Zones - A Systematic Review.","authors":"Tiffanie-Marie Borg, Naveen Cavale, Ghassan Abu-Sittah, Ali Ghanem","doi":"10.1177/19433875221083416","DOIUrl":"10.1177/19433875221083416","url":null,"abstract":"<p><strong>Study design: </strong>Injuries sustained in war-zones are variable and constantly developing according to the nature of the ongoing conflict. Soft tissue involvement of the extremities, head and neck often necessitates reconstructive expertise. However, current training to manage injuries in such settings is heterogenous. This study involves a systematic review.</p><p><strong>Objective: </strong>To evaluate interventions in place to train Plastic and Maxillofacial surgeons for war-zone environments so that limitations to current training can be addressed.</p><p><strong>Methods: </strong>A literature search of Medline and EMBase was performed using terms relevant to Plastic and Maxillofacial surgery training and war-zone environments. Articles that met the inclusion criteria were scored then educational interventions described in included literature were categorised according to their length, delivery style and training environment. Between-group ANOVA was performed to compare training strategies.</p><p><strong>Results: </strong>2055 citations were identified through this literature search. Thirty-three studies were included in this analysis. The highest scoring interventions were over an extended time-frame with an action-oriented training approach, using simulation or actual patients. Core competencies addressed by these strategies included technical and non-technical skills necessary when working in war-zone type settings.</p><p><strong>Conclusions: </strong>Surgical rotations in trauma centers and areas of civil strife, together with didactic courses are valuable strategies to train surgeons for war-zones. These opportunities must be readily available globally and be targeted to the surgical needs of the local population, anticipating the types of combat injuries that often occur in these environments.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10645397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Likelihood of Craniofacial Injury and Hospitalization with Alcohol Use While Skateboarding and Scootering. 滑板和滑行时饮酒导致颅面损伤和住院的可能性。
IF 0.9 Pub Date : 2023-03-01 Epub Date: 2022-01-21 DOI: 10.1177/19433875211069219
Thomas J Sorenson, Matthew D Rich, Annika Deitermann, Rachael Gotlieb, Nicholas Garcia, Ruth J Barta, Warren Schubert

Study Design: We designed a cross-sectional epidemiologic study to evaluate the influence of substance use on craniofacial injuries in a population of skateboard and scooter users. Objective: The primary outcome of our study was craniofacial injury. The secondary outcome was hospitalization. Methods: We report a cross-sectional study of patients reported to the National Electronic Injury Surveillance System (NEISS) from January 1, 2019, to December 31, 2020, in the United States. Patients were included in our study if they were evaluated in the emergency department (ED) for a skateboard- or scooter-related injury. Results: There were over 5396 total patients who presented to a NEISS-participating ED after skateboard- or scooter- related trauma during the study period. There were 1136 patients with a craniofacial injury (primary endpoint), and patients under the influence of alcohol or drugs had greater odds of experiencing a craniofacial injury than those not under the influence (odds ratio [OR]: 4.16, 95% confidence interval [CI]: 3.24-5.32, P < .0001). Four hundred-thirty patients were hospitalized (secondary endpoint), and patients under the influence had greater odds of being hospitalized than those not under the influence (OR: 2.83, 95% CI: 2.04-3.91, P < .0001). Conclusions: Alcohol and drug use while skateboarding or scootering drastically increases the likelihood of craniofacial injury and subsequent hospitalization and should be avoided whenever possible. The importance of wearing a helmet while operating these devices cannot be overstated.

研究设计:我们设计了一项横断面流行病学研究,以评估在滑板和滑板车使用者群体中使用药物对颅面损伤的影响。研究目的我们研究的主要结果是颅面部损伤。次要结果是住院治疗。研究方法我们报告了一项横断面研究,研究对象是 2019 年 1 月 1 日至 2020 年 12 月 31 日期间向美国国家电子伤害监测系统(NEISS)报告的患者。因滑板或滑板车相关伤害而在急诊科(ED)接受评估的患者均被纳入研究范围。研究结果在研究期间,共有超过 5396 名患者因滑板或滑板车相关创伤而前往参与 NEISS 的急诊科就诊。与未受酒精或药物影响的患者相比,受酒精或药物影响的患者发生颅面部损伤的几率更高(几率比 [OR]:4.16,95% 置信区间 [CI]:3.24-5.32,P < .0001)。有 430 名患者住院治疗(次要终点),与未受影响的患者相比,受影响的患者住院治疗的几率更高(OR:2.83,95% 置信区间[CI]:2.04-3.91,P < .0001)。结论在滑板或滑行时饮酒或吸毒会大大增加颅面部受伤及随后住院的可能性,因此应尽可能避免。在操作这些设备时佩戴头盔的重要性怎么强调都不为过。
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引用次数: 0
Analysis of Neoclassical Canons in Adult Kenyans of Indian Descent. 印度裔肯尼亚成年人的新古典主义信条分析。
IF 0.9 Pub Date : 2023-03-01 Epub Date: 2022-01-19 DOI: 10.1177/19433875221077005
Krishan Sarna, Tom Mulama Osundwa, Martin Kamau, Khushboo Jayant Sonigra

Study Design: Descriptive cross-sectional. Objective: To establish anthropometric norms and test the validity of four neoclassical canons among Kenyans of Indian descent. Methods: Using direct anthropometric landmarks, 3 vertical and 4 horizontal measurements were made on the faces of 130 adult Kenyans of Indian descent. The mean of each anthropometric measurement was calculated and a student t-test was used to identify significant gender differences. These results were compared to four neoclassical canons and the percentage of each canon and its variants were recorded. A chi-square test was then performed to assess any gender differences between these findings. Results: When comparing sexes, the anthropometric means of males were larger than those of females except for eye fissure length. In addition, only the upper third displayed sexual dimorphism. As for the neoclassical canons, the orbital canon was found to apply to 20.0% of males and 21.6% of females, followed by the naso-oral canon found in 16.4% of males and 17.6% of females, and the orbito-nasal canon present in 14.5% of males and 18.9% of females. The vertical canon was not found to be applicable to any participant. Conclusion: The facial morphometric measurements in this population differ from the described neoclassical canons since they do not apply to the majority of these individuals. Therefore surgeons should be guided by the observed population-specific differences during reconstructive and facial aesthetic surgery.

研究设计:描述性横断面研究目的在印度裔肯尼亚人中建立人体测量标准,并检验四种新古典标准的有效性。方法:使用直接的人体测量标志物进行测量:使用直接人体测量地标,对 130 名印度裔肯尼亚成年人的面部进行 3 次垂直测量和 4 次水平测量。计算每个人体测量值的平均值,并使用学生 t 检验来确定显著的性别差异。将这些结果与四种新古典主义标准进行比较,并记录每种标准及其变体的百分比。然后进行卡方检验,以评估这些结果之间是否存在性别差异。结果比较性别时,除眼裂长度外,男性的人体测量平均值大于女性。此外,只有上三分之一部位显示出性别二态性。在新古典主义标准方面,20.0% 的男性和 21.6% 的女性采用眼眶标准,16.4% 的男性和 17.6% 的女性采用鼻-口标准,14.5% 的男性和 18.9% 的女性采用眼-鼻标准。没有发现任何受试者有垂直卡农。结论该人群的面部形态测量与所描述的新古典主义标准不同,因为它们不适用于这些人中的大多数。因此,外科医生在进行整形和面部美容手术时应以观察到的特定人群差异为指导。
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引用次数: 0
The Most Dangerous Game: A Review of Head and Neck Injuries in American Football and Rugby. 最危险的游戏:美式橄榄球和橄榄球中的头颈部损伤回顾。
IF 0.9 Pub Date : 2023-03-01 Epub Date: 2022-01-13 DOI: 10.1177/19433875211073437
Jordan Richardson, Dani Stanbouly, Harrison Moynihan, Renée M Reynolds, Matthew J Recker, Michael R Markiewicz

Study design: The investigators designed and implemented a 20-year cross-sectional study using the National Electronic Injury Surveillance System database.

Objective: The purpose of this study is to estimate and compare hospital admission (danger) rates between rugby and football of those who presented to the emergency department with head and neck injuries after playing these sports.

Methods: The primary predictor variable was sport played. The primary outcome variable was danger, measured by hospital admission rates.

Results: Over the past 20 years, there has been a trend of decreasing incidence of injuries presenting to the emergency department in both sports. There was no difference in the rate of hospital admission when comparing football and rugby (OR, 1.2; P = .1). Male gender was associated with an increased risk of admission. Other variables associated with hospital admission included white racial group, injury taking place in the fall, being either young (15-24 years old) or senior (65 years of age and over), and being injured at school or at a sport/recreational facility.

Conclusions: There is no difference in danger as measured by admission rates between American football and rugby. There exists, however, several variables that are associated with admission when sustaining injury to the head and neck, when playing these two sports.

研究设计:研究人员利用国家电子伤害监测系统数据库设计并实施了一项为期 20 年的横断面研究:本研究的目的是估算并比较橄榄球和足球运动中因头部和颈部受伤而到急诊科就诊的患者的入院率(危险):主要预测变量是所从事的运动。主要结果变量是危险程度,以入院率衡量:结果:在过去 20 年中,这两种运动在急诊科的受伤发生率呈下降趋势。足球和橄榄球的入院率没有差异(OR,1.2;P = .1)。男性与入院风险增加有关。与入院相关的其他变量包括:白人、摔伤、年轻(15-24 岁)或年长(65 岁及以上)、在学校或体育/娱乐设施受伤:从入院率来看,美式橄榄球和橄榄球的危险性没有区别。但是,在进行这两种运动时,有几个变量与头部和颈部受伤入院有关。
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引用次数: 0
Comparison of Teriparatide and Combination of Cissus Quadrangularis and Dalbergia Sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-label Control Trial. 在颌面部骨折患者中,对比特立帕肽与四裂叶松和Dalbergia Sissoo复方制剂对骨愈合的影响:一项随机开放标签对照试验。
IF 0.9 Pub Date : 2023-03-01 Epub Date: 2022-01-19 DOI: 10.1177/19433875211067007
Gigi Pg, Ankita Chugh, Kirti Chaudhry, Amanjot Kaur, Pravin Kumar, Shubham Gaur, Shailendra Kumar, Surjit Singh

Study design: Randomized Control Trial.

Objective: A randomized control trial was planned to aim to assess whether subcutaneous Injection of Teriparatide and Tablet Reunion (combination of Cissus Quadrangularis and Dalbergia sissoo) improves maxillofacial fracture healing as compared to the control group.

Methods: 24 patients of mandibular fracture with or without concomitant maxillofacial fractures were randomly divided into 3 equal groups (Group 1- Control, Group 2- Tablet Reunion, and Group 3- Injection Teriparatide) and the treatment duration was 4 weeks. Pain, fracture site mobility, bite force, serum markers, and radiographic healing were assessed preoperatively and postoperatively at regular intervals till 12 weeks.

Results: Group 2 showed early pain relief, although it was insignificant. Group 3 showed the highest anterior bite force at all the time points. Change in mean posterior bite force (PBF) showed a statistically significant increase at 8th week and 12th week in intergroup comparison; however, at 12th week, Group 3 was significantly better than Group 1 and reported the highest posterior bite force compared to other groups. Serum calcium and PTH level showed no significant difference, whereas Serum ALP showed a statistically significant increase in Group 3. The radiographic assessment showed no significant difference among the 3 groups.

Conclusions: Both the intervention group drugs showed a promising effect on accelerating the fracture healing and improving bite force restoration with the osteoanabolic action; however, early radiographic healing and increased serum osteogenic markers in Group 3 indicate its possible optimistic role in maxillofacial fracture healing.

研究设计随机对照试验:与对照组相比,皮下注射特立帕肽和复方片剂(Cissus Quadrangularis和Dalbergia sissoo的复方制剂)是否能改善颌面部骨折愈合。方法:将24名下颌骨骨折患者随机分为3组(对照组1、复方片剂2和注射特立帕肽3),治疗时间为4周。术前和术后定期评估疼痛、骨折部位活动度、咬合力、血清标志物和影像学愈合情况,直至 12 周:结果:第 2 组早期疼痛缓解,但不明显。第 3 组在所有时间点均显示出最高的前咬合力。在第 8 周和第 12 周,平均后咬合力(PBF)的变化在组间比较中显示出统计学意义上的显著增加;然而,在第 12 周,第 3 组明显优于第 1 组,与其他组相比,第 1 组的后咬合力最高。血清钙和 PTH 水平无明显差异,而血清 ALP 在第 3 组有明显增加:两组干预药物在加速骨折愈合和改善咬合力恢复方面均显示出良好的骨合成作用;然而,第 3 组的早期影像学愈合和血清成骨标志物的增加表明其在颌面部骨折愈合中可能发挥乐观作用。
{"title":"Comparison of Teriparatide and Combination of Cissus Quadrangularis and Dalbergia Sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-label Control Trial.","authors":"Gigi Pg, Ankita Chugh, Kirti Chaudhry, Amanjot Kaur, Pravin Kumar, Shubham Gaur, Shailendra Kumar, Surjit Singh","doi":"10.1177/19433875211067007","DOIUrl":"10.1177/19433875211067007","url":null,"abstract":"<p><strong>Study design: </strong>Randomized Control Trial.</p><p><strong>Objective: </strong>A randomized control trial was planned to aim to assess whether subcutaneous Injection of Teriparatide and Tablet Reunion (combination of Cissus Quadrangularis and <i>Dalbergia sissoo</i>) improves maxillofacial fracture healing as compared to the control group.</p><p><strong>Methods: </strong>24 patients of mandibular fracture with or without concomitant maxillofacial fractures were randomly divided into 3 equal groups (Group 1- Control, Group 2- Tablet Reunion, and Group 3- Injection Teriparatide) and the treatment duration was 4 weeks. Pain, fracture site mobility, bite force, serum markers, and radiographic healing were assessed preoperatively and postoperatively at regular intervals till 12 weeks.</p><p><strong>Results: </strong>Group 2 showed early pain relief, although it was insignificant. Group 3 showed the highest anterior bite force at all the time points. Change in mean posterior bite force (PBF) showed a statistically significant increase at 8th week and 12th week in intergroup comparison; however, at 12th week, Group 3 was significantly better than Group 1 and reported the highest posterior bite force compared to other groups. Serum calcium and PTH level showed no significant difference, whereas Serum ALP showed a statistically significant increase in Group 3. The radiographic assessment showed no significant difference among the 3 groups.</p><p><strong>Conclusions: </strong>Both the intervention group drugs showed a promising effect on accelerating the fracture healing and improving bite force restoration with the osteoanabolic action; however, early radiographic healing and increased serum osteogenic markers in Group 3 indicate its possible optimistic role in maxillofacial fracture healing.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10769484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Craniomaxillofacial Trauma & Reconstruction
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