Reumatologia Clinica最新文献

英文中文

Do psychosocial factors predict disease severity in fibromyalgia syndrome? 心理社会因素能预测纤维肌痛综合征的病情严重程度吗？

IF 1.2 Q4 RHEUMATOLOGY

Reumatologia Clinica

Pub Date : 2025-05-01 Epub Date: 2025-06-04 DOI: 10.1016/j.reuma.2025.501893

Hasan Huseyin Gokpinar , Cihan Caner Aksoy , Muhammed Fatih Ozdemir , İsmail Saraçoğlu

Objective

The aim of this study was to examine anxiety, depression, pain centralization, and pain catastrophization in patients with fibromyalgia syndrome (FMS) and evaluate whether these factors are predictors of disease severity in FMS.

Patient and methods

Depression was assessed with the Beck Depression Inventory (BDI), anxiety with the Beck Anxiety Inventory (BAI), pain centralization with the Centrality of Pain Scale (COPS), pain catastrophization with the Pain Catastrophizing Scale (PCS), and FMS severity with the Fibromyalgia Impact Questionnaire (FIQ). Two separate hierarchical linear regression analyses were performed to determine whether there was a significant association between disease severity and the assessed psychosocial factors.

Results

The study was completed with a total of 48 FMS patients (mean age 49.54 ± 8.28 years). FIQ score was moderately correlated with COPS score (r_Spearman = 0.670, p < 0.001) and PCS score (r_Spearman = 0.663, p < 0.001). In the logistic regression model, COPS and PCS scores were significant predictors of FIQ score. The predictive variables explained 43.7% of the variation in FIQ score.

Conclusion

This study showed that pain centralization and catastrophization can be considered indicators of disease severity in FMS. The results suggest that routine assessment of pain centralization and pain catastrophizing behaviors in individuals with FMS is needed and that cognitive behavioral therapy approaches may be beneficial in reducing disease severity.

目的本研究旨在探讨纤维肌痛综合征（FMS）患者的焦虑、抑郁、疼痛集中和疼痛灾难化，并评估这些因素是否为FMS疾病严重程度的预测因素。患者和方法采用贝克抑郁量表（BDI）、贝克焦虑量表（BAI）、疼痛中心性量表（COPS）、疼痛灾难化量表（PCS）和纤维肌痛影响问卷（FIQ）分别对患者进行抑郁、焦虑、疼痛集中和FMS严重程度的评估。进行了两次单独的分层线性回归分析，以确定疾病严重程度与评估的社会心理因素之间是否存在显著关联。结果共48例FMS患者（平均年龄49.54±8.28岁）完成研究。FIQ评分与COPS评分呈正相关(rSpearman = 0.670, p <；0.001)和PCS评分(rSpearman = 0.663, p <；0.001)。在logistic回归模型中，COPS和PCS得分是FIQ得分的显著预测因子。预测变量解释了43.7%的FIQ得分变异。结论疼痛集中和巨化可作为FMS疾病严重程度的指标。结果表明，有必要对FMS患者的疼痛集中和疼痛灾难化行为进行常规评估，认知行为治疗方法可能有助于降低疾病严重程度。

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RS3PE post-COVID: nueva evidencia de enfermedades autoinmunes tras la infección por SARS-CoV-2 新冠病毒后的RS3PE: SARS-CoV-2感染后自身免疫性疾病的新证据

IF 1.2 Q4 RHEUMATOLOGY

Reumatologia Clinica

Pub Date : 2025-05-01 Epub Date: 2025-06-02 DOI: 10.1016/j.reuma.2025.501898

Begoña Miquel Veyrat, José Chordá Ribelles, Mar Gómez Martí

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Índice de autores 作者索引

IF 1.2 Q4 RHEUMATOLOGY

Reumatologia Clinica

Pub Date : 2025-05-01 Epub Date: 2025-07-25 DOI: 10.1016/S1699-258X(25)00149-4

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Osteomalacia hipofosfatémica secundaria a tumor mesenquimal 继发性低磷酸骨髓瘤至间充质瘤

IF 1.2 Q4 RHEUMATOLOGY

Reumatologia Clinica

Pub Date : 2025-05-01 Epub Date: 2025-06-02 DOI: 10.1016/j.reuma.2025.501897

Aurora González Murcia , Isabel Valencia Ramírez , Teresa Catalina Plaza Aguado , José Antonio González Ferrández

We present the case of a 42-year-old male patient who is admitted for the study of axial and pelvic girdle pain, being diagnosed with hypophosphatemic osteomalacia secondary to a mesenchymal tumor after ruling out other causes of osteomalacia.

我们提出一个42岁的男性病人，他入院研究轴和骨盆带痛，在排除其他原因的骨软化症后，被诊断为继发于间质肿瘤的低磷血症性骨软化症。

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Trabajos aceptados solo para publicación 只接受出版的作品

IF 1.2 Q4 RHEUMATOLOGY

Reumatologia Clinica

Pub Date : 2025-05-01 Epub Date: 2025-07-25 DOI: 10.1016/S1699-258X(25)00145-7

引用次数: 0

Junta Directiva de la SER, Comité de Organización de Congresos, Comité Científico del Congreso y Comité Organizador Local del Congreso SER理事会、大会组织委员会、大会科学委员会和大会地方组织委员会

IF 1.2 Q4 RHEUMATOLOGY

Reumatologia Clinica

Pub Date : 2025-05-01 Epub Date: 2025-07-25 DOI: 10.1016/S1699-258X(25)00143-3

引用次数: 0

Pósteres: P1-P170 海报:P1-P170

IF 1.2 Q4 RHEUMATOLOGY

Reumatologia Clinica

Pub Date : 2025-05-01 Epub Date: 2025-07-25 DOI: 10.1016/S1699-258X(25)00146-9

引用次数: 0

Pósteres: P171-P318 海报:P171-P318

IF 1.2 Q4 RHEUMATOLOGY

Reumatologia Clinica

Pub Date : 2025-05-01 Epub Date: 2025-07-25 DOI: 10.1016/S1699-258X(25)00147-0

引用次数: 0

Estudio del impacto de la inclusión de la valoración global del dolor y la capacidad funcional en la definición de remisión y su mantenimiento en la artritis reumatoide. Objetivos y metodología 研究将疼痛和功能的整体评估纳入缓解定义及其在类风湿关节炎中的维持的影响。目标和方法

IF 1.2 Q4 RHEUMATOLOGY

Reumatologia Clinica

Pub Date : 2025-05-01 Epub Date: 2025-06-03 DOI: 10.1016/j.reuma.2025.501895

Alejandro Balsa , Daniel Seoane-Mato , Marta Domínguez-Álvaro , Mercedes Alperi , Virginia Ruiz-Esquide , Javier Bachiller-Corral , Federico Díaz-González , en representación del Grupo del estudio Remisión-AR

Background and objective

The SUMAR project established a definition for remission that includes the patient's perspective (global assessment of pain and HAQ) in the definition of remission in rheumatoid arthritis (RA). This new definition needs to be assessed on clinical practice. The main objective of the RA-Remission study is to estimate the proportion of patients in sustained remission according to SUMAR definition through 2-year follow-up, among patients in SUMAR remission at baseline. This manuscript describes the objectives and methodology of the study.

Materials and methods

This is a longitudinal, prospective, observational and multicentre study, involving 10 centres. Patients with RA who have achieved clinical remission in accordance to their attending rheumatologist clinical judgement within the last 6 months will be included. Follow-up visits will take place at 3, 6, 12, 12, 18 and 24 months. Ultrasound assessment of the power Doppler (PD) signal for 30 joints and 6 tendon regions will be performed at each participating centre by an expert blinded to all other study findings. Definitions of remission according to SUMAR, PD and activity indices will be used. Sustained remission will be considered for each of the definitions when the patient in remission at the baseline visit maintains it during all follow-up visits. To estimate the proportion of patients maintaining remission at two years with an accuracy of at least 6%, 180 patients will need to be recruited.

Discussion and conclusions

The main strength of the design is the use of ultrasound assessment as the gold standard for assessing inflammatory activity.

背景和目的：SUMAR项目建立了缓解的定义，包括患者的视角（疼痛和HAQ的整体评估）来定义类风湿关节炎（RA）的缓解。这个新的定义需要在临床实践中进行评估。ra -缓解研究的主要目的是通过2年随访，估计基线时SUMAR缓解的患者中根据SUMAR定义持续缓解的患者比例。这份手稿描述了研究的目的和方法。材料和方法这是一项纵向、前瞻性、观察性和多中心研究，涉及10个中心。根据其主治风湿病医生的临床判断，在过去6个月内达到临床缓解的RA患者将被包括在内。随访将在3、6、12、12、18和24个月进行。每个参与中心将由一名不知道其他研究结果的专家对30个关节和6个肌腱区域的功率多普勒（PD）信号进行超声评估。根据SUMAR、PD和活动指数来定义缓解。当患者在基线访视时处于缓解状态，并在所有随访期间保持缓解状态时，将考虑每一种定义的持续缓解。为了估计在两年内保持缓解的患者比例，且准确性至少为6%，需要招募180名患者。讨论与结论本设计的主要优点是使用超声评估作为评估炎症活动的金标准。

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引用次数: 0

Ocular inflammatory manifestations in patients with rheumatoid arthritis 类风湿关节炎患者的眼部炎症表现

IF 1.2 Q4 RHEUMATOLOGY

Reumatologia Clinica

Pub Date : 2025-05-01 Epub Date: 2025-06-03 DOI: 10.1016/j.reuma.2025.501891

Raul E. Ruiz-Lozano , Luis Arnaldo Prida-Espaillat , Reinaldo A. Moll-Auais , Eugenia M. Ramos-Dávila , Manuel E. Quiroga-Garza , Aaron Zhao , Ali Khodor , Amr Almobayed , David Vega-Morales , Alejandro Rodriguez-Garcia

Purpose

This review emphasizes the significance of clinical findings, pathogenic mechanisms, diagnosis, management, and complications related to the ocular manifestations of rheumatoid arthritis, underscoring the need for interdisciplinary collaboration between rheumatologists and ophthalmologists.

Methods

A comprehensive literature search was conducted using PubMed, Embase, Web of Science, and Google Scholar for all English-language articles published from inception to July 2024. The following search string was utilized: (“rheumatoid arthritis”) AND (“dry eye disease” OR “dry eye” OR “episcleritis” OR “scleritis” OR “peripheral ulcerative keratitis” OR “central corneal ulcer*” OR “paracentral corneal ulcer*” OR “ocular manifestations” OR “ocular involvement”). Letters to the editor, editorials, short communications, case reports, case series, review articles, and original articles were reviewed, along with relevant references from those publications.

Results

The most common ocular manifestations in patients with rheumatoid arthritis include keratoconjunctivitis sicca (dry eye disease), episcleritis, scleritis, peripheral ulcerative keratitis, and central and paracentral corneal ulceration. Ocular involvement can be the initial presentation of the disease and may correlate with disease activity. If left untreated, ocular inflammation in rheumatoid arthritis can lead to permanent vision loss.

Conclusions

The diverse ocular inflammatory manifestations in RA patients may indicate either the disease's initial presentation or the status of extra-articular activity. A multidisciplinary approach that includes rheumatologists and ophthalmologists is essential to prevent sight-threatening complications.

目的综述类风湿关节炎眼部表现的临床表现、发病机制、诊断、治疗和并发症的重要性，强调风湿病学家和眼科医生之间跨学科合作的必要性。方法利用PubMed、Embase、Web of Science、b谷歌Scholar等数据库对自成立以来至2024年7月发表的所有英文论文进行综合文献检索。使用以下搜索字符串：（“类风湿性关节炎”）和（“干眼病”或“干眼”或“外巩膜炎”或“巩膜炎”或“周围性溃疡性角膜炎”或“中央性角膜溃疡*”或“中央旁性角膜溃疡*”或“眼部表现”或“眼部受累”）。审查了给编辑的信、社论、简短通讯、病例报告、病例系列、评论文章和原始文章，以及这些出版物的相关参考文献。结果类风湿性关节炎患者最常见的眼部表现为干眼病、表皮炎、巩膜炎、周围性溃疡性角膜炎、中央和中央旁性角膜溃疡。眼部受累可能是疾病的最初表现，并可能与疾病活动有关。如果不及时治疗，类风湿性关节炎引起的眼部炎症会导致永久性视力丧失。结论RA患者不同的眼部炎症表现可能表明疾病的初始表现或关节外活动的状态。包括风湿病学家和眼科医生在内的多学科方法对于预防威胁视力的并发症至关重要。

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