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Fibre composition in sow diets influences bile acid profile in colostrum and in intestinal digesta of their new-born suckling piglets. 母猪饲粮中纤维成分对初生哺乳仔猪初乳和肠道食糜中胆汁酸分布有影响。
IF 2 Q3 NUTRITION & DIETETICS Pub Date : 2025-11-04 eCollection Date: 2025-01-01 DOI: 10.1017/jns.2025.10050
Łukasz Marcin Grześkowiak, Ignacio Rodolfo Ipharraguerre, Gerald Rimbach, Wilfried Vahjen, Jürgen Zentek

Dietary fibre can modify colostrum and milk composition in sows. Bile acids (BA) aid in fat digestion and lipid absorption and are important signalling molecules for the digestive tract. The aim of this study was to determine BA concentration in colostrum from sows fed two different sources of dietary fibre during gestation and lactation and from the intestinal digesta of their 4-6-days-old suckling offspring. Twenty sows were fed diets enriched with either 15% high-fermentable sugar beet pulp (SBP, n = 10) or 15% low-fermentable lignocellulose (LNC, n = 10). Sow colostrum, piglet gallbladder content, ileum and colon digesta were assessed for BA using high-performance liquid chromatography coupled to triple-quadrupole mass spectrometry. In colostrum, lithocholic acid and oxolithocholic acid were higher in sows fed SBP vs. LNC (p = 0.005 and p = 0.003, respectively), while 3α,7α,12α-trihydroxycholestanoic acid and glycohyodeoxycholic acid were higher in colostrum from sows fed LNC vs. SBP (p = 0.039, p = 0.002, respectively). In the piglet bile, cholic acid and taurodeoxycholic acid were higher in SBP vs. LNC group (p = 0.02, p = 0.001, respectively), while taurochenodeoxycholic acid was higher in LNC vs. SBP group (p = 0.035). In the piglet ileum digesta, lithocholic acid was higher in SBP vs. LNC (p = 0.015). In the piglet colon digesta, lithocholic acid and ursodeoxycholic acid were higher in SBP vs. LNC (p = 0.001 and p = 0.007, respectively). Addition of specific dietary fibres to sow diets differentially influences the BA in colostrum. Dietary fibres in sow diets can impact on the intestinal BA composition in piglets with a possible consequence on the digestive physiology and health in the offspring.

饲粮纤维可改变母猪初乳和乳成分。胆汁酸(BA)有助于脂肪消化和脂质吸收,是消化道重要的信号分子。本研究的目的是测定妊娠期和哺乳期饲喂两种不同膳食纤维来源的母猪初乳中的BA浓度,以及4-6日龄哺乳后代肠道食糜中的BA浓度。20头母猪分别饲喂添加15%高发酵性甜菜粕(SBP, n = 10)和15%低发酵性木质纤维素(LNC, n = 10)的饲粮。采用高效液相色谱-三重四极杆质谱联用技术对母猪初乳、仔猪胆囊内容物、回肠和结肠食糜进行BA测定。初乳中石胆酸和氧化石胆酸含量分别高于低脂猪(p = 0.005和p = 0.003), 3α、7α、12α-三羟基胆酸和糖羟基去氧胆酸含量分别高于低脂猪(p = 0.039和p = 0.002)。在仔猪胆汁中,SBP组的胆酸和牛磺酸去氧胆酸高于LNC组(p = 0.02, p = 0.001), LNC组的牛磺酸去氧胆酸高于SBP组(p = 0.035)。在仔猪回肠食糜中,石胆酸在收缩压中的含量高于LNC (p = 0.015)。在仔猪结肠食糜中,石胆酸和熊去氧胆酸在收缩压中高于LNC (p = 0.001和p = 0.007)。母猪饲粮中添加特定膳食纤维对初乳BA的影响不同。母猪饲粮中的膳食纤维会影响仔猪肠道BA组成,并可能对后代的消化生理和健康产生影响。
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引用次数: 0
Sustainable diets: where from and where to? 可持续饮食:从哪里来,到哪里去?
IF 2 Q3 NUTRITION & DIETETICS Pub Date : 2025-11-03 eCollection Date: 2025-01-01 DOI: 10.1017/jns.2025.10049
Lesley Macheka, Rebecca Kanter, Mark Lawrence, Sandro Dernini, Farah Naja, Stineke Oenema

The multilevel dimensions of sustainable diets associating food systems, public health, environmental sustainability, and culture are presented in this paper. It begins by defining sustainable diets as those that are healthful, have low environmental impacts, are affordable, and culturally acceptable. The discussion includes the history of research on sustainable diets, from initial studies focused on environmental impacts to more recent, comprehensive frameworks that integrate affordability, cultural relevance, and nutritional adequacy as key dimensions of diet sustainability. In addition, the paper highlights recent innovations, such as the Planetary Health Diet of EAT-Lancet and the SHARP model, and the conflicts and optimum trade-offs between sustainability and nutrition, particularly within low- and middle-income countries. Case descriptions of Mediterranean Diet with a focus on Traditional Lebanese Diet, and African Indigenous Foods demonstrate culturally confined dietary patterns associated with sustainability objectives. These examples show that sustainable diets are not a single set of prescriptions, but a series of multiple pathways that are shaped by local food environments, ecological belts, and sociocultural heritages. The paper also describes major policy and governance activities necessary to promote sustainable diets. Finally, the paper addresses measurement challenges and advocates for better indicator options to measure sustainable food systems in all their facets and for participatory and context-specific approaches. The discussion concludes that fairer and culturally diverse inclusion strategies, system change, and political determination are imperative in achieving sustainable diets. Diets able to sustain are posited as agents capable of driving the 2030 agenda, enhancing planetary health and social integrity.

可持续饮食的多个层面相关的粮食系统,公共卫生,环境可持续性和文化在本文中提出。它首先将可持续饮食定义为那些健康、对环境影响小、负担得起、文化上可接受的饮食。讨论包括可持续饮食的研究历史,从最初的研究关注环境影响到最近的综合框架,将可负担性、文化相关性和营养充足性作为饮食可持续性的关键维度。此外,该文件还强调了最近的创新,例如《柳叶刀》和SHARP模式的“地球健康饮食”,以及可持续性与营养之间的冲突和最佳权衡,特别是在低收入和中等收入国家。以传统黎巴嫩饮食和非洲土著食品为重点的地中海饮食的案例描述,展示了与可持续性目标相关的受文化限制的饮食模式。这些例子表明,可持续饮食不是一套单一的处方,而是一系列受当地食物环境、生态带和社会文化遗产影响的多种途径。本文还介绍了促进可持续饮食所需的主要政策和治理活动。最后,本文阐述了测量方面的挑战,并倡导采用更好的指标选项来衡量可持续粮食系统的各个方面,以及采用参与式和因地制宜的方法。讨论的结论是,更公平和文化多样化的包容战略、制度变革和政治决心是实现可持续饮食的必要条件。可持续饮食被认为是能够推动《2030年议程》、增进地球健康和社会诚信的因素。
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引用次数: 0
Maternal exposure to a radio programme and maternal and child nutrition-related practices: cross-sectional analyses of the 2022 Nepal Demographic and Health Survey. 产妇收听广播节目和妇幼营养相关做法:2022年尼泊尔人口与健康调查的横断面分析。
IF 2 Q3 NUTRITION & DIETETICS Pub Date : 2025-10-30 eCollection Date: 2025-01-01 DOI: 10.1017/jns.2025.10048
Ramesh Prasad Adhikari, Subir K Kole, Pooja Pandey Rana, Indra D Kshetri, Kenda Cunningham

This paper examines associations between maternal exposure to a radio programme, Bhanchhin Aama (Mother Knows Best), and the programme's most promoted maternal and child nutrition-related practices, using the Nepal Demographic and Health Survey (NDHS) from 2022. We limited our sample to mothers of children less than 2 years (n = 1,933). The primary exposure variable was whether the mother listened to the Bhanchhin Aama radio programme. The five primary outcomes were: maternal dietary diversity, maternal use of modern family planning methods, exclusive breastfeeding (EBF) of children less than 6 months, dietary diversity among children 6 to 24 months, and participation in growth monitoring and promotion among children 0 to 24 months. Descriptive analyses followed by logistic regression models, adjusted for potentially confounding factors and clustering, were conducted. Maternal exposure to Bhanchhin Aama was associated with nearly 70% higher odds of meeting both maternal (OR: 1.67; p: <0.001; CI: 1.26-2.21) and child minimum dietary diversity (OR: 1.70; p: 0.005; CI: 1.18-2.45), as well as 83% higher odds of a child participating in growth monitoring and promotion (OR: 1.83; p: 0.001; CI: 1.28-2.63). No associations were found for use of modern family planning methods and EBF. These findings suggests that radio programmes may be an effective tool to improve some maternal and child nutrition-related practices. Further research is needed to understand why certain behaviours are modifiable from this type of intervention versus others that are not and for which population groups this intervention would be most effective.

本文利用尼泊尔人口与健康调查(NDHS)从2022年开始,研究了孕产妇接触广播节目Bhanchhin Aama(母亲最了解)与该节目最推广的妇幼营养相关做法之间的关系。我们将样本限制在2岁以下儿童的母亲(n = 1,933)。主要的暴露变量是母亲是否听过巴钦阿玛广播节目。五个主要结局是:产妇饮食多样性、产妇使用现代计划生育方法、6个月以下儿童的纯母乳喂养(EBF)、6至24个月儿童的饮食多样性以及0至24个月儿童参与生长监测和促进。描述性分析之后进行了逻辑回归模型,调整了潜在的混杂因素和聚类。母亲接触Bhanchhin Aama的几率增加了近70% (OR: 1.67; p: p: 0.005; CI: 1.18-2.45),儿童参与生长监测和促进的几率增加了83% (OR: 1.83; p: 0.001; CI: 1.28-2.63)。没有发现使用现代计划生育方法与EBF有关联。这些发现表明,广播节目可能是改善一些与孕产妇和儿童营养有关的做法的有效工具。需要进一步的研究来理解为什么某些行为可以通过这种干预来改变,而其他行为则不能,以及这种干预对哪些人群最有效。
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引用次数: 0
A scoping review of interventions aiming to improve food security for low-income families with school-aged children outside of school hours. 对旨在改善有学龄儿童的低收入家庭在课外的粮食安全的干预措施进行范围审查。
IF 2 Q3 NUTRITION & DIETETICS Pub Date : 2025-10-29 eCollection Date: 2025-01-01 DOI: 10.1017/jns.2025.10047
Grace Podmore Baker, Naomi J Ellis, Gillian Forrester, Aman S Mankoo, Christopher J Gidlow

Food insecurity is a global issue. The objective is to summarise the literature identifying the main outcomes related to out-of-school hours interventions that provide food for low-income families with school-aged children, how they impact school-aged children and their families, and to identify gaps in knowledge. This review covered the main types and dimensions proposed in the literature. One author independently selected the studies, and an independent reviewer randomly reviewed them. Any paper meeting the inclusion criteria was considered regardless of geographical location. Papers were predominantly from the US, UK and Australia, including school-aged children from low-income families. Ninety-four articles were included relating to holiday clubs (n = 38), breakfast clubs (n = 45) and after-school clubs (n = 11). Key outcomes were healthy eating, academic, social, physical activity, nutritional education and financial outcomes. Clubs were consistent regarding the positive social and financial outcomes. There was variation in the primary aim, either to improve healthy eating or to feed children, regardless of nutritional quality. None of the studies reported children's health outcomes. This review identified the key outcomes of interventions for low-income families outside of school hours in the literature. It highlights the consistent positive social outcomes across the three intervention types and the discrepancy in the nutritional value of the food provided. Few studies examined the attainment impact of holiday clubs, with no evidence on how they could impact term-time attendance. This highlights the need to analyse secondary data to understand further the attainment and attendance impact on children attending these interventions over time.

粮食不安全是一个全球性问题。目的是总结文献,确定与校外时间干预有关的主要结果,这些干预为有学龄儿童的低收入家庭提供食物,它们如何影响学龄儿童及其家庭,并确定知识差距。本综述涵盖了文献中提出的主要类型和维度。一名作者独立选择了这些研究,一名独立的审稿人随机审查了这些研究。任何符合纳入标准的论文都将被考虑,无论地理位置如何。论文主要来自美国、英国和澳大利亚,其中包括来自低收入家庭的学龄儿童。94篇文章涉及假日俱乐部(n = 38)、早餐俱乐部(n = 45)和课后俱乐部(n = 11)。主要结果包括健康饮食、学业、社交、体育活动、营养教育和财务结果。俱乐部在积极的社会和财务结果方面是一致的。主要目标各不相同,要么是改善健康饮食,要么是喂养儿童,而不考虑营养质量。没有一项研究报告了儿童的健康状况。本综述确定了文献中对低收入家庭在课外时间进行干预的主要结果。它强调了三种干预类型中一致的积极社会结果以及所提供食物的营养价值的差异。很少有研究考察了假日俱乐部对成就的影响,也没有证据表明它们会如何影响学期出勤率。这凸显了分析次要数据的必要性,以进一步了解随着时间的推移,参加这些干预措施的儿童的成绩和出勤率影响。
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引用次数: 0
Exploring the link among eating behaviour, diet quality, and relative energy deficiency in sports risk in elite Canadian volleyball male athletes. 探讨加拿大优秀男子排球运动员的饮食行为、饮食质量和相对能量缺乏在运动风险中的关系。
IF 2 Q3 NUTRITION & DIETETICS Pub Date : 2025-10-24 eCollection Date: 2025-01-01 DOI: 10.1017/jns.2025.10046
Erik Sesbreno, Louise Capling, Margo Mountjoy, Anne-Sophie Brazeau

Male volleyball athletes may be at risk of inadequate energy and carbohydrate intake. This may increase their risk of relative energy deficiency in sport (REDs) and impair a variety of physiological and psychological systems involved with performance and health. This study explored the eating behaviours and diet quality of international elite volleyball male athletes and their association on hormones associated with acute energy deficit and primary serum REDs indicators outlined in the International Olympic Committee REDs Clinical Assessment Tool 2.

Methods: Using a retrospective design, 30 male athletes from a national indoor volleyball programme were assessed using DXA bone mineral density, hematological analysis, anthropometry, restrained eating behaviour via the Three-Factor Eating Questionnaire-R18 and the Athlete Diet Index (ADI) questionnaire.

Results: All participants met or exceeded dietary recommendations for health and sport with ADI mean score of 95.2/125 ± 10.5. Restraint eating was inversely associated with insulin (r = - 0.37; p  < 0.05). Both the ADI total and core nutrition sub-scores were inversely associated with free-triiodothyronine (r = - 0.58; p < 0.01) but not with total testosterone, insulin or leptin.

Conclusion: Male volleyball athletes at risk of inadequate energy intake may not necessarily demonstrate signs of poor diet quality.

男子排球运动员可能面临能量和碳水化合物摄入不足的风险。这可能会增加他们在运动中相对能量缺乏(red)的风险,并损害与表现和健康有关的各种生理和心理系统。本研究探讨了国际优秀排球男运动员的饮食行为和饮食质量,以及它们与急性能量不足相关的激素和国际奥委会red临床评估工具2中列出的主要血清red指标的关系。方法:采用回顾性设计,对30名国家室内排球项目男运动员进行DXA骨密度、血液学分析、人体测量、进食三因素问卷r18和运动员饮食指数(ADI)问卷的饮食行为进行评估。结果:所有参与者均达到或超过健康和运动饮食建议,ADI平均评分为95.2/125±10.5。克制进食与胰岛素呈负相关(r = - 0.37; p < 0.05)。ADI总评分和核心营养评分与游离三碘甲状腺原氨酸呈负相关(r = - 0.58; p < 0.01),但与总睾酮、胰岛素或瘦素无关。结论:有能量摄入不足风险的男排运动员不一定表现出饮食质量差的迹象。
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引用次数: 0
Beliefs and behaviours associated with vegetarian, vegan, and gluten-free diets among Canadians capable of bearing children. 有生育能力的加拿大人与素食、纯素食和无麸质饮食相关的信仰和行为。
IF 2 Q3 NUTRITION & DIETETICS Pub Date : 2025-10-14 eCollection Date: 2025-01-01 DOI: 10.1017/jns.2025.10044
Olivia Morello, Erica Pellizzari, Madeline Erlich, Brenda Hartman

There is increased interest in self-selected exclusionary diet patterns, specifically vegetarian, vegan, and gluten-free (GF) diets, but there is a lack of research exploring the beliefs and behaviours surrounding these diets in Canadians capable of bearing children (CCBC). The goal of this study was to explore the beliefs and behaviours of CCBC who follow vegetarian, vegan, and/or GF diets using mixed methods. A self-administered online Qualtrics™ survey containing 102 questions was conducted using open text and closed format questions. Continuous variables were summarized using mean and standard deviation while percentages were used to summarize categorical variables. Qualitative data was analysed using thematic analysis. A total of 271 CCBC between 18-45 years of age were analysed, with 27%, 22%, and 3.7% indicating they followed a vegan, vegetarian, and/or GF diet, respectively. Three main themes emerged that influenced CCBC beliefs about their chosen diet. The belief that these diets are healthy or could impart health in some way, was the main reason for following their chosen diet, especially in those who identified as vegetarian. Ethical/moral concerns, primarily around animal welfare and the environment, was the second theme for following their chosen dietary pattern, especially amongst those who identified as vegan. Perception of social judgement in the forms of criticism, guilt, and isolation were noted by some CCBC, with family, friends, and colleagues interacting differently with them because of their dietary choices. These findings serve to enhance our understanding of the beliefs and behaviours of CCBC who choose to follow exclusionary diets.

人们对自我选择的排他饮食模式越来越感兴趣,特别是素食、纯素食和无谷蛋白(GF)饮食,但缺乏对有生育能力的加拿大人(CCBC)围绕这些饮食的信仰和行为的研究。本研究的目的是探讨使用混合方法遵循素食、纯素和/或无糖饮食的CCBC的信仰和行为。一项自我管理的在线Qualtrics™调查包含102个问题,采用开放文本和封闭格式的问题进行。连续变量用均值和标准差汇总,分类变量用百分比汇总。定性数据采用专题分析进行分析。共分析了271例年龄在18-45岁之间的CCBC,分别有27%、22%和3.7%的人表示他们遵循纯素、素食和/或无糖饮食。三个主要主题影响了CCBC对他们选择的饮食的看法。相信这些饮食是健康的,或者在某种程度上可以带来健康,是遵循他们选择的饮食的主要原因,尤其是那些认为自己是素食主义者的人。伦理/道德问题,主要围绕动物福利和环境,是遵循他们所选择的饮食模式的第二个主题,特别是那些被认定为素食主义者的人。一些CCBC注意到以批评、内疚和孤立的形式感知社会判断,由于他们的饮食选择,家人、朋友和同事与他们的互动方式不同。这些发现有助于增强我们对选择排他性饮食的CCBC的信念和行为的理解。
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引用次数: 0
A convenience sample based market survey of the food additive monosodium glutamate (MSG) in processed foods in Malaysia. 马来西亚加工食品中食品添加剂味精(味精)的便利抽样市场调查。
IF 2 Q3 NUTRITION & DIETETICS Pub Date : 2025-10-13 eCollection Date: 2025-01-01 DOI: 10.1017/jns.2025.10039
Jia Yin Chow, Suzana Shahar, Hasnah Haron, Ying Qian Ong

Although studies had suggested that monosodium glutamate (MSG) may serve as a salt substitute in processed foods, its market impact remains unclear. This study was aimed to: (1) identify MSG in ingredient lists, (2) compare sodium levels in products with and without MSG, (3) examine the association between MSG and other umami enhancers, and (4) assess manufacturers' adherence to the Food Regulation 1985 for MSG declaration. An observational cross-sectional market survey was conducted during the Movement Control Order (June to September 2021) on 1076 processed foods from selected Malaysian hypermarkets, that were located within 10 km of the researcher's residence to ensure accessibility amid the COVID-19 pandemic movement restrictions. Additionally, online platforms were used to supplement any missing data. Nutritional and ingredient information were collected from packaging, and foods were classified by using the FAO/WHO Food Standards CODEX Alimentarius. Over half (50.8%) of the surveyed products contained MSG. Results found that MSG-containing products had a significantly higher sodium levels (2812.2 ± 5191.4 mg/100 g) than those without (1372.2 ± 1541.4 mg/100 g) (p < 0.001). Additionally, 14.4% of MSG-free products were labelled as 'No Added MSG', while products with MSG were more likely to contain other umami enhancers (p < 0.001). Compliance with MSG declaration regulations was 61%. In conclusion, MSG was present in half of the surveyed products. MSG-containing products were more likely to have higher sodium content and include other flavour enhancers. Future research should analyse the actual MSG as well as sodium content and explore alternative sodium reduction strategies.

尽管研究表明,味精(MSG)可以作为加工食品中的盐替代品,但其市场影响尚不清楚。本研究的目的是:(1)在配料表中识别味精;(2)比较含味精和不含味精产品中的钠含量;(3)检验味精和其他鲜味增强剂之间的关系;(4)评估制造商对1985年食品法规味精声明的遵守情况。在流动管制令实施期间(2021年6月至9月),研究人员对位于研究人员住所10公里范围内的选定马来西亚大型超市的1076种加工食品进行了观察性横断面市场调查,以确保在COVID-19大流行期间的通行限制。此外,在线平台被用来补充任何缺失的数据。从包装上收集营养和成分信息,并根据粮农组织/世卫组织食品标准(食品法典)对食品进行分类。超过一半(50.8%)的被调查产品含有味精。结果发现,含味精产品的钠含量(2812.2±5191.4 mg/100 g)显著高于不含味精产品(1372.2±1541.4 mg/100 g) (p < 0.001)。此外,14.4%的无味精产品标有“无添加味精”,而含有味精的产品更有可能含有其他鲜味增强剂(p < 0.001)。符合味精申报规定的比例为61%。总之,味精存在于一半的调查产品中。含有味精的产品更有可能含有较高的钠含量,并含有其他增味剂。未来的研究应该分析实际的味精和钠含量,并探索替代的减钠策略。
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引用次数: 0
Individual and environmental factors influencing the dietary behaviour of healthcare workers during night shifts in the Netherlands: a qualitative study. 影响荷兰夜班医护人员饮食行为的个人和环境因素:一项定性研究。
IF 2 Q3 NUTRITION & DIETETICS Pub Date : 2025-10-10 eCollection Date: 2025-01-01 DOI: 10.1017/jns.2025.10041
Fleur van Elk, Karen M Oude Hengel, Coen Dros, Alex Burdorf, Heidi M Lammers-van der Holst

This qualitative descriptive study aimed to explore dietary habits among healthcare workers during night shifts and to identify individual and environmental factors that influence their dietary behaviour during night shifts. Individual semi-structured interviews were conducted with twenty-five healthcare night female workers, which were recruited via email invitations from managers and posters placed in central workplaces at a university medical centre in the Netherlands. The interview protocol was developed following an integrated behaviour change model focusing on individual (I-Change model, i.e., awareness, motivation, intention, and ability) and environmental (Environmental Research framework for weight Gain prevention at environmental level (EnRG), i.e., physical, policy-related, economic, and sociocultural) factors. Inductive analyses were conducted to explore dietary habits, while deductive thematic analysis was applied to identify potential factors influencing dietary behaviour. Female healthcare workers in night shifts generally made poorer dietary choices during night shifts than during other shifts. Seven key themes were coded for dietary behaviour. Based on the domains of the integrated behaviour change model, four individual and five environmental key themes were established, within which 41 sub-themes were coded. Key individual factors included awareness (i.e., lack of knowledge about timing and type of consumption) and motivation (i.e., attitude and efficacy to eat healthy). Critical environmental factors included physical and sociocultural work environment, organisation of work, and lack of organisational policies. To conclude, future dietary interventions for healthcare night workers should target both individual behaviours and the workplace environment, with an emphasis on raising awareness and enhancing organisational policies to promote healthy dietary habits.

本定性描述性研究旨在探讨夜班医护人员的饮食习惯,并确定影响其夜班饮食行为的个人和环境因素。研究人员对25名保健夜班女工进行了半结构化的访谈,这些女工是通过经理的电子邮件邀请和张贴在荷兰一所大学医疗中心中心工作场所的海报招募的。访谈方案是根据一个综合的行为改变模型制定的,该模型侧重于个人(I-Change模型,即意识、动机、意图和能力)和环境(环境层面预防体重增加的环境研究框架,即物理、政策相关、经济和社会文化)因素。采用归纳分析探讨饮食习惯,采用演绎主题分析确定影响饮食行为的潜在因素。夜班女性卫生保健工作者在夜班期间的饮食选择通常比其他班次差。饮食行为有七个关键主题。基于综合行为改变模型的域,建立了4个个体和5个环境关键主题,其中41个子主题编码。关键的个人因素包括意识(即缺乏关于消费时间和类型的知识)和动机(即健康饮食的态度和功效)。关键的环境因素包括物理和社会文化的工作环境,工作的组织,以及缺乏组织政策。总之,未来针对夜班保健工作者的饮食干预应针对个人行为和工作场所环境,重点是提高认识和加强组织政策,以促进健康的饮食习惯。
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引用次数: 0
Effects of coenzyme Q10 supplementation on myopathy in statin-treated patients: a systematic review and meta-analysis. 补充辅酶Q10对他汀类药物治疗患者肌病的影响:系统回顾和荟萃分析。
IF 2 Q3 NUTRITION & DIETETICS Pub Date : 2025-10-10 eCollection Date: 2025-01-01 DOI: 10.1017/jns.2025.10043
Svenja Kovacic, Sandra D Habicht, Gunter Peter Eckert

Statins are effective drugs for lowering hypercholesterolemia and preventing cardiovascular diseases. They can cause various side effects, in particular statin-associated muscle symptoms (SAMS) associated with mitochondrial dysfunction and micronutrient depletion. The aim of this systematic review and meta-analysis was to investigate the efficacy of a supplementation with Coenzyme Q10 (CoQ10) against SAMS in statin-treated patients. A systematic literature search was performed in Medline and Cochrane Library in August 2024. Studies were selected for a meta-analysis according to the following criteria: randomised controlled trials (RCTs), adults taking statins (any type and dose), supplementation of CoQ10, a comparable control group, and muscle pain as outcome criterion. Cochrane Risk of Bias tool was used for bias assessment. Seven RCTs with 389 patients in total were included in this meta-analysis. The selected studies included 35 to 76 patients and had a duration ranging from 30 to 90 days with CoQ10 dosages ranging from 100 to 600 mg per day. Results show a significant reduction of SAMS in four trials and no significant change in three trials. Overall, a significant reduction in SAMS, measured as pain intensity, after CoQ10 supplementation was found: weighted mean difference (WMD) -0.96 (95% Confidence Interval -1.88; -0.03), p < 0.05. Supplementation of CoQ10 can reduce muscle pain in patients with SAMS, which is relevant for their well-being and treatment continuation. More research is needed for evidence-based recommendations.

他汀类药物是降低高胆固醇血症和预防心血管疾病的有效药物。它们可引起各种副作用,特别是与线粒体功能障碍和微量营养素消耗相关的他汀类药物相关肌肉症状(SAMS)。本系统综述和荟萃分析的目的是研究补充辅酶Q10 (CoQ10)对他汀类药物治疗患者SAMS的疗效。于2024年8月在Medline和Cochrane Library进行了系统的文献检索。根据以下标准选择研究进行荟萃分析:随机对照试验(rct),服用他汀类药物(任何类型和剂量)的成年人,补充辅酶q10,可比较的对照组,肌肉疼痛作为结果标准。采用Cochrane偏倚风险评估工具进行偏倚评估。本荟萃分析纳入了7项随机对照试验,共389例患者。选定的研究包括35至76名患者,持续时间为30至90天,辅酶q10剂量为每天100至600毫克。结果显示,4项试验中SAMS显著降低,3项试验无显著变化。总体而言,CoQ10补充后SAMS(以疼痛强度衡量)显著降低:加权平均差(WMD) -0.96(95%可信区间-1.88;-0.03),p < 0.05。补充辅酶q10可以减轻SAMS患者的肌肉疼痛,这与他们的健康和治疗的持续有关。基于证据的建议需要更多的研究。
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引用次数: 0
Gestational diabetes and changes in dietary quality and food group consumption before and during pregnancy: a pilot cross-sectional study in Malawian women attending antenatal clinics. 妊娠糖尿病与怀孕前和怀孕期间饮食质量和食物组消费的变化:在产前诊所就诊的马拉维妇女中进行的一项试验性横断面研究。
IF 2 Q3 NUTRITION & DIETETICS Pub Date : 2025-10-10 eCollection Date: 2025-01-01 DOI: 10.1017/jns.2025.10042
Getrude Mphwanthe, Friday Saidi, Maganizo B Chagomerana, Oswin Kamangira, Priscilla Phiri, Charles Nyirongo, Triza Columbus, Lustia Mndoliro, Jonathan Misolo, Felistace Mtande, Lorraine Weatherspoon

This pilot cross-sectional study, conducted in two public hospitals in Malawi, assessed gestational diabetes mellitus (GDM) in pregnant women attending antenatal clinics and compared their dietary quality and food group consumption before and during pregnancy. The study targeted women aged 18 to 49 years within 24 to 28 weeks of gestation. GDM was diagnosed according to the International Association of Diabetes and Pregnancy Study Group criteria and assessed dietary quality before and during pregnancy using a 30-day qualitative food frequency questionnaire. We compared changes in dietary quality and specific food group mean scores using paired t-tests at p < 0.05. Of the 508 women enrolled, 22.7% were diagnosed with GDM. The overall diet quality significantly decreased during pregnancy compared to before; a similar trend was observed in women diagnosed with GDM compared to those without GDM (p < 0.0001). Among women with GDM, the mean score of the following food groups significantly (p < 0.05) decreased during pregnancy: cruciferous vegetables, deep orange vegetables and tubers, citrus fruits, deep orange fruits, other fruits, nuts and seeds, poultry, fish, low fat dairy, whole grains, and liquid oils and significantly (p < 0.05) increased in the following food groups; red meat, processed meat, sugar-sweetened beverages, sweets, sugary snacks and ice cream. In conclusion, GDM is prevalent in Malawian women enrolled in this study and is coupled with inadequate dietary quality, especially during pregnancy. Since dietary quality is pivotal to GDM management, more in-depth longitudinal dietary studies are needed to inform nutritional interventions to prevent and better manage GDM.

在马拉维的两家公立医院进行的这项试验性横断面研究,评估了在产前诊所就诊的孕妇的妊娠糖尿病(GDM),并比较了她们在怀孕前和怀孕期间的饮食质量和食物组消费。这项研究的对象是怀孕24到28周、年龄在18到49岁之间的女性。根据国际糖尿病和妊娠研究小组的标准诊断GDM,并使用30天定性食物频率问卷评估怀孕前和怀孕期间的饮食质量。我们使用配对t检验比较饮食质量和特定食物组平均得分的变化,p < 0.05。在入选的508名女性中,22.7%被诊断为GDM。与怀孕前相比,怀孕期间的整体饮食质量明显下降;在诊断为GDM的女性中,与未诊断为GDM的女性相比,观察到类似的趋势(p < 0.0001)。在GDM妇女中,以下食物组的平均评分在怀孕期间显著(p < 0.05)降低:十字花科蔬菜、深橙色蔬菜和块茎、柑橘类水果、深橙色水果、其他水果、坚果和种子、家禽、鱼类、低脂乳制品、全谷物和液体油,并在以下食物组中显著(p < 0.05)升高;红肉、加工肉类、含糖饮料、糖果、含糖零食和冰淇淋。总之,GDM在参与本研究的马拉维妇女中普遍存在,并伴有饮食质量不足,尤其是在怀孕期间。由于饮食质量是GDM管理的关键,因此需要更深入的纵向饮食研究,为营养干预提供信息,以预防和更好地管理GDM。
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引用次数: 0
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Journal of Nutritional Science
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