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Association of serum docosahexaenoic acid and eicosapentaenoic acid levels with dietary intakes and supplement use during pregnancy: a prospective observational study 血清二十二碳六烯酸和二十碳五烯酸水平与孕期膳食摄入量和补充剂使用量的关系:一项前瞻性观察研究
IF 2.5 Q3 NUTRITION & DIETETICS Pub Date : 2023-12-14 DOI: 10.1017/jns.2023.105
Nana Wakabayashi, Megumi Haruna, Kaori Yonezawa, Emi Sasagawa, Yuriko Usui, Riko Ohori, Satoko Aoyama, Satoshi Sasaki, Takeshi Nagamatsu
Abstract Abstract This study aimed to determine the association of serum docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) levels with dietary intakes and supplement use during pregnancy. This prospective observational study was conducted at a university hospital in Tokyo, Japan. Participants in their second and third trimesters were given a self-administered questionnaire assessing the frequency of DHA and EPA supplement use in the past month and a brief-type self-administered diet history questionnaire. Non-fasting serum DHA and EPA levels were analysed using gas chromatography. Differences in biomarkers by frequency of supplement use were determined using multiple comparison analyses, and Spearman's correlation coefficient was used to determine biomarkers and DHA and EPA intakes by food group. Of the 116 participants, 11 (9⋅5 %) in the second trimester and 18 (15⋅5 %) in the third trimester regularly used supplements (≥5 times per week). Regular users had higher serum DHA and EPA levels than never users in the second and third trimesters. Dietary DHA and EPA intake from fish and shellfish was positively correlated with serum DHA and EPA in the second and third trimesters. Supplement use ≥5 times per week and fish and shellfish intake were associated with high serum DHA and EPA levels.
摘要 本研究旨在确定血清中二十二碳六烯酸(DHA)和二十碳五烯酸(EPA)水平与孕期膳食摄入量和补充剂使用量之间的关系。这项前瞻性观察研究在日本东京的一家大学医院进行。研究人员向怀孕第二和第三个月的孕妇发放了一份自填式问卷,评估她们在过去一个月中使用 DHA 和 EPA 补充剂的频率,并发放了一份简短的自填式饮食史问卷。采用气相色谱法分析了非空腹血清中的 DHA 和 EPA 水平。使用多重比较分析确定补充剂使用频率与生物标志物之间的差异,使用斯皮尔曼相关系数确定生物标志物与食物组中 DHA 和 EPA 摄入量之间的差异。在 116 名参与者中,有 11 人(9⋅5%)在怀孕的第二个三个月和 18 人(15⋅5%)在怀孕的第三个三个月经常使用补充剂(每周≥5 次)。与从未使用过保健品的孕妇相比,经常使用保健品的孕妇在第二和第三个孕期的血清中 DHA 和 EPA 含量更高。从鱼类和贝类中摄入的 DHA 和 EPA 与第二和第三个孕期的血清 DHA 和 EPA 呈正相关。每周使用补充剂≥5 次以及鱼类和贝类摄入量与高血清 DHA 和 EPA 水平有关。
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引用次数: 0
Development of mobile phone-based dietary data collection applications in pregnant women and infants for the M-SAKHI trial 为 M-SAKHI 试验开发基于手机的孕妇和婴儿饮食数据收集应用程序
IF 2.5 Q3 NUTRITION & DIETETICS Pub Date : 2023-12-13 DOI: 10.1017/jns.2023.95
Shilpa Bhaise, Archana Patel, Varsha Dhurde, Michelle Almeida, Tran Do, Sumithra Muthayya, Michael Dibley
Abstract In nutritional epidemiological studies, it is imperative to collect high-quality data to ensure accurate dietary assessment. However, dietary data collection using traditional paper forms has several limitations that may compromise data quality. The aim of this study was to propose novel methods to design and develop software applications (Apps) for dietary data collection to assess the nutritional status of pregnant women and infants. This study is part of the M-SAKHI (Mobile-Solutions for Aiding Knowledge for Health Improvement) cluster randomised controlled trial (cRCT) implemented in central India. Three tablet-based software Apps were developed in this study: the ACEC (Automated Coding and Energy Calculation) App to establish a generic cooked food recipe database, the FFQ (Food Frequency Questionnaire), and the IDR (24 h Infant Dietary Recall) Apps to collect dietary data from pregnant women and their infants from rural area of Bhandara and Nagpur districts. Regional food lists, recipes, and portion resource kits were developed to support the data collection using the Apps. In conclusion, the Apps were user-friendly, required minimal prior training, had built-in validation checks for erroneous data entry and provided automated calculations. The Apps were successfully deployed in low-resource rural settings to accurately collect high-quality regional cooked food data and individual-level dietary data of pregnant women and their infants.
在营养流行病学研究中,收集高质量的数据是保证准确膳食评估的必要条件。然而,使用传统纸质表格收集膳食数据有一些限制,可能会影响数据质量。本研究的目的是提出设计和开发用于膳食数据收集的软件应用程序(Apps)的新方法,以评估孕妇和婴儿的营养状况。这项研究是在印度中部实施的M-SAKHI(帮助改善健康知识的移动解决方案)集群随机对照试验(cRCT)的一部分。本研究开发了三个基于平板电脑的软件应用程序:ACEC(自动编码和能量计算)应用程序,用于建立通用熟食配方数据库;FFQ(食物频率问卷)应用程序;IDR(24小时婴儿饮食回忆)应用程序,用于收集班达拉和那格浦尔农村地区孕妇及其婴儿的饮食数据。开发了区域食物清单、食谱和份量资源包,以支持使用应用程序进行数据收集。总之,这些应用程序是用户友好的,需要最少的事先培训,内置了对错误数据输入的验证检查,并提供了自动计算。这些应用程序成功地部署在资源匮乏的农村环境中,以准确收集高质量的区域熟食数据和孕妇及其婴儿的个人饮食数据。
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引用次数: 0
Importance of Palm's heart for pregnant women – CORRIGENDUM 棕榈心对孕妇的重要性 - CORRIGENDUM
IF 2.5 Q3 NUTRITION & DIETETICS Pub Date : 2023-12-11 DOI: 10.1017/jns.2023.110
Efrem Negash Kushi, T. Belachew, Dessalegn Tamiru
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引用次数: 0
The relationship between parent's self-reported exposure to food marketing and child and parental purchasing and consumption outcomes in five countries: findings from the International Food Policy Study 在五个国家,父母自我报告的食品营销接触情况与儿童和父母的购买和消费结果之间的关系:国际食品政策研究的结果
IF 2.5 Q3 NUTRITION & DIETETICS Pub Date : 2023-12-07 DOI: 10.1017/jns.2023.88
Julia Soares Guimarães, Elise Pauzé, Monique Potvin Kent, S. Barquera, A. Jáuregui, Gary Sacks, L. Vanderlee, David Hammond
Abstract Food and beverage marketing influences children's food preferences and dietary intake. Children's diets are also heavily influenced by their family environment. The aim of this study was to assess the relationship between parent's self-reported exposure to unhealthy food marketing and a range of outcomes related to children's desire for and intake of unhealthy foods and beverages. The study also sought to examine whether these outcomes varied across different countries. The analysed data are from the International Food Policy Study and were collected in 2018 using an online survey. The sample included 5764 parents of children under 18, living in Australia, Canada, Mexico, the United Kingdom, or the United States. Binary logistic regressions assessed the link between the number of parental exposure locations and children's requests for and parental purchases of unhealthy foods. Generalized ordinal regression gauged the relationship between the number of exposure locations and children's consumption of such items. Interaction terms tested if these associations varied by country. Parental exposure to unhealthy food marketing was positively associated with parents reporting child purchase requests and purchase outcomes; and differed by country. Increased parental exposure to unhealthy food marketing was associated with slightly lower odds of children's weekly consumption of unhealthy foods, and this association varied by country. In conclusion, parental report of a greater range of food marketing exposure was associated with a range of outcomes that would increase children's exposure to unhealthy food products or their marketing. Governments should consider developing more comprehensive restrictions on the marketing of unhealthy foods.
食品和饮料营销影响儿童的食物偏好和膳食摄入量。儿童的饮食也深受家庭环境的影响。本研究的目的是评估父母自我报告的不健康食品营销与儿童对不健康食品和饮料的渴望和摄入相关的一系列结果之间的关系。该研究还试图检查这些结果是否在不同的国家有所不同。分析的数据来自国际粮食政策研究,并于2018年通过在线调查收集。样本包括5764名18岁以下儿童的父母,他们生活在澳大利亚、加拿大、墨西哥、英国或美国。二元逻辑回归评估了父母接触地点的数量与儿童对不健康食品的要求和父母购买之间的联系。广义有序回归测量了暴露地点的数量与儿童对此类物品的消费之间的关系。相互作用项测试了这些关联是否因国家而异。父母接触不健康食品营销与父母报告儿童购买请求和购买结果呈正相关;不同国家的情况也不同。父母接触不健康食品营销的增加与儿童每周消费不健康食品的几率略低有关,这种关联因国家而异。综上所述,父母报告的更大范围的食品营销接触与一系列结果相关,这些结果会增加儿童对不健康食品或其营销的接触。各国政府应考虑对不健康食品的营销制定更全面的限制。
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引用次数: 0
Prevalence of vitamin E inadequacy, dietary intake and sources of alpha-tocopherol, and predictors of alpha- and gamma-tocopherol status in adolescent girls in Central Mozambique 莫桑比克中部少女维生素 E 不足的普遍程度、α-生育酚的膳食摄入量和来源以及α-和γ-生育酚状况的预测因素
IF 2.5 Q3 NUTRITION & DIETETICS Pub Date : 2023-12-01 DOI: 10.1017/jns.2023.103
L. Korkalo, Georg Alfthan, L. Fidalgo, R. Freese
Abstract An adequate alpha-tocopherol status is important for females at reproductive age. We studied the dietary intake and sources of alpha-tocopherol and alpha- and gamma-tocopherol status indicators in 14–19-year-old girls in Central Mozambique. We also explored factors associated with alpha- and gamma-tocopherol status. The participants (n 508) were from the cross-sectional ZANE Study that was conducted in 2010. We recruited two separate samples, one in January–February and the other in May–June. We collected venous blood samples and conducted 24 h dietary recall interviews. At the time of blood sampling, 11 % of participants were pregnant and 10 % were lactating. In the total sample, both seasons combined, the median intake of alpha-tocopherol was 6⋅7 mg/d, the mean plasma alpha- and gamma-tocopherol concentrations were 13⋅5 and 0⋅75 μmol/l, respectively, and the prevalence of vitamin E inadequacy (alpha-tocopherol <12 μmol/l) was 36⋅7 % (95 % CI: 31⋅9–42⋅0 %). Season and lactation status were significant predictors of alpha-tocopherol status regardless of which the three indicators (plasma concentration, alpha-tocopherol:total cholesterol ratio, gamma-tocopherol:alpha-tocopherol ratio) were used. Being a lactating mother was negatively associated and having a blood sample taken in January–February, when the main sources of alpha-tocopherol were mango and dark green leafy vegetables, was positively associated with alpha-tocopherol status. In conclusion, vitamin E inadequacy was common in Central Mozambique, and the status may fluctuate due to seasonal changes in the diet. We suggest that lactating mothers are specifically at risk of poor alpha-tocopherol status in resource-poor settings.
充足的α -生育酚对育龄女性很重要。我们研究了莫桑比克中部14 - 19岁女孩的饮食摄入和α -生育酚以及α和γ -生育酚状态指标的来源。我们还探讨了与α -和γ -生育酚状态相关的因素。参与者(508人)来自2010年进行的横断面ZANE研究。我们招募了两个独立的样本,一个在1月至2月,另一个在5月至6月。我们采集静脉血样本并进行24小时饮食回忆访谈。在抽血时,11%的参与者怀孕了,10%的参与者正在哺乳。在两个季节的总样本中,α -生育酚的中位数摄入量为6⋅7 mg/d,血浆α -和γ -生育酚的平均浓度分别为13⋅5和0⋅75 μmol/l,维生素E不足(α -生育酚<12 μmol/l)的发生率为36⋅7% (95% CI: 31⋅9-42⋅0%)。无论使用何种三个指标(血浆浓度、α -生育酚:总胆固醇比率、γ -生育酚:α -生育酚比率),季节和哺乳期状态都是α -生育酚状态的重要预测因子。哺乳期母亲与α -生育酚水平呈负相关,而在1 - 2月采集血液样本(芒果和深绿色绿叶蔬菜是α -生育酚的主要来源)与α -生育酚水平呈正相关。综上所述,维生素E不足在莫桑比克中部地区很常见,而且由于饮食的季节性变化,情况可能有所波动。我们认为,在资源贫乏的环境中,哺乳期母亲尤其有α -生育酚状态差的风险。
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引用次数: 0
Effects of green tea polyphenols on inflammation and iron status. 绿茶多酚对炎症和铁状况的影响。
IF 2.5 Q3 NUTRITION & DIETETICS Pub Date : 2023-11-30 eCollection Date: 2023-01-01 DOI: 10.1017/jns.2023.107
Mary Carolyn Jorgenson, Sixtus Aguree, Kevin L Schalinske, Manju B Reddy

Inflammation is an underlying problem for many disease states and has been implicated in iron deficiency (ID). This study aimed to determine whether iron status is improved by epigallocatechin-3-gallate (EGCG) through reducing inflammation. Thirty-two male Sprague-Dawley rats were fed an iron-deficient diet for 2 weeks and then randomly divided into four groups (n 8 each): positive controls, negative controls, lipopolysaccharide (LPS, 0⋅5 mg/kg body weight), and LPS + EGCG (LPS plus 600 mg EGCG/kg diet) for 3 additional weeks. The study involved testing two control groups, both treated with saline. One group (positive control) was fed a regular diet containing standard iron, while the negative control was fed an iron-deficient diet. Additionally, two treatment groups were tested. The first group was given LPS, while the second group was administered LPS and fed an EGCG diet. Iron status, hepcidin, C-reactive protein (CRP), serum amyloid A (SAA), and interleukin-6 (IL-6) were measured. There were no differences in treatment groups compared with control in CRP, hepcidin, and liver iron concentrations. Serum iron concentrations were significantly lower in the LPS (P = 0⋅02) and the LPS + EGCG (P = 0⋅01) than in the positive control group. Compared to the positive control group, spleen iron concentrations were significantly lower in the negative control (P < 0⋅001) but not with both LPS groups. SAA concentrations were significantly lower in the LPS + EGCG group compared to LPS alone group. EGCG reduced SAA concentrations but did not affect hepcidin or improve serum iron concentration or other iron markers.

炎症是许多疾病的潜在问题,也与缺铁症(ID)有关。本研究旨在确定表没食子儿茶素-3-棓酸盐(EGCG)是否能通过减少炎症来改善铁的状态。研究人员给32只雄性Sprague-Dawley大鼠喂食缺铁饮食2周,然后将其随机分为4组(每组8只):阳性对照组、阴性对照组、脂多糖组(LPS,0⋅5毫克/千克体重)和LPS + EGCG组(LPS加600毫克EGCG/千克饮食),再喂食3周。该研究包括测试两个对照组,两组都用生理盐水处理。其中一组(阳性对照组)采用含标准铁的普通饮食,而阴性对照组则采用缺铁饮食。此外,还测试了两个治疗组。第一组给予 LPS,第二组给予 LPS 并喂食 EGCG。对铁的状态、血钙素、C反应蛋白(CRP)、血清淀粉样蛋白A(SAA)和白细胞介素-6(IL-6)进行了测定。与对照组相比,治疗组的 CRP、血钙素和肝铁浓度没有差异。LPS 组(P = 0⋅02 )和 LPS + EGCG 组(P = 0⋅01 )的血清铁浓度明显低于阳性对照组。与阳性对照组相比,阴性对照组的脾脏铁浓度明显降低(P < 0⋅001),但与 LPS 两组相比则没有明显降低。与单用LPS组相比,LPS + EGCG组的SAA浓度明显降低。EGCG可降低SAA浓度,但不会影响血红素或改善血清铁浓度或其他铁标记物。
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引用次数: 0
Meat, vegetable, and fruit consumption among urban and rural elders aged 60+ years in regional China: a population-level nutritional study. 中国地区 60 岁以上城市和农村老年人的肉类、蔬菜和水果消费量:一项人群营养研究。
IF 2.5 Q3 NUTRITION & DIETETICS Pub Date : 2023-11-30 eCollection Date: 2023-01-01 DOI: 10.1017/jns.2023.104
Guilin Zhang, Jian Kang, Shibao Jing, Yinhao Chen, Tianrui Deng, Huiqing Xu, Haidi Wu, Fei Xu

The aim was to assess epidemiological characteristics of the most recent consumption patterns of meat, vegetable, and fruit among representative urban and rural residents aged 60+ years in regional China. In this cross-sectional survey conducted in mid-2018, participants aged 60+ years were randomly chosen from urban and rural communities in Nanjing municipality of China. Meat, vegetable, and fruit intake were assessed with a validated food frequency questionnaire. Multivariate logistic regression models were applied to compute odds ratio (OR) and 95 % confidence interval (CI) to investigate the association of socio-demographic characteristics with a likelihood of meeting intake recommendation. Among the 20 867 participants, 49⋅5 % were men and 45⋅0 % urban elders, and 6⋅5 % aged 80+ years. The mean values of consumption frequency of red meat, white meat, vegetable, and fruit were 2⋅99 ± 2⋅28, 1⋅37 ± 1⋅13, 5⋅24 ± 6⋅43, and 2⋅64 ± 2⋅91 times/week, respectively, among overall participants. Moreover, there were 14⋅9, 23⋅7, and 12⋅1 % of participants meeting intake recommendations of meat, vegetable, and fruit, separately, in this study. After adjustment for potential confounders, age, gender, residence area, and educational attainment each was associated with the likelihood of meeting intake recommendation of meat, vegetable, or fruit. The consumption frequency and proportion of participants meeting intake recommendations of meat, vegetable, or fruit were not high among elders in regional China. Socio-demographic characteristics were associated with intake recommendations of meat, vegetables, and fruit. It has public health implications that participants' socio-demographic attributes shall be considered for precision intervention on meat, vegetable, and fruit consumption in healthy eating campaigns among elders in China.

目的是评估中国地区具有代表性的60岁以上城乡居民肉类、蔬菜和水果最新消费模式的流行病学特征。这项横断面调查于 2018 年年中进行,参与者从中国南京市的城市和农村社区中随机抽取,年龄在 60 岁以上。通过有效的食物频率问卷评估了肉类、蔬菜和水果的摄入量。采用多变量逻辑回归模型计算几率比(OR)和 95 % 置信区间(CI),以研究社会人口特征与达到推荐摄入量的可能性之间的关系。在20 867名参与者中,49.5%为男性,45.0%为城市长者,6.5%为80岁以上长者。所有参与者每周食用红肉、白肉、蔬菜和水果的次数平均值分别为 2⋅99 ± 2⋅28 次、1⋅37 ± 1⋅13 次、5⋅24 ± 6⋅43 次和 2⋅64 ± 2⋅91 次。此外,本研究中分别有 14⋅9% 、23⋅7% 和 12⋅1% 的参与者达到了肉类、蔬菜和水果的建议摄入量。在对潜在的混杂因素进行调整后,年龄、性别、居住地区和教育程度分别与达到肉类、蔬菜或水果摄入量建议的可能性相关。在中国地区的老年人中,达到肉类、蔬菜或水果建议摄入量的食用频率和比例并不高。社会人口特征与肉类、蔬菜和水果的摄入推荐量有关。在中国老年人健康饮食活动中对肉类、蔬菜和水果的摄入进行精准干预时,应考虑参与者的社会人口学特征,这对公共卫生具有重要意义。
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引用次数: 0
The association between dietary intake of macro- and micronutrients and multimorbidity: a cross-sectional study in Cyprus. 饮食摄入宏量和微量营养素与多发病之间的关系:塞浦路斯的一项横断面研究。
IF 2.5 Q3 NUTRITION & DIETETICS Pub Date : 2023-11-24 eCollection Date: 2023-01-01 DOI: 10.1017/jns.2023.102
Maria Kyprianidou, Stavri Chrysostomou, Kosmia Andreou, Agni Alexandrou, Rafaella Panagiotou, Costas A Christophi, Konstantinos Giannakou

Research on the link between diet and multimorbidity is scarce, despite significant studies investigating the relationship between diet and individual chronic conditions. This study examines the association of dietary intake of macro- and micronutrients with multimorbidity in Cyprus's adult population. It was conducted as a cross-sectional study, with data collected using a standardised questionnaire between May 2018 and June 2019. The questionnaire included sociodemographic information, anthropometrics, medical history, dietary habits, sleep quality, smoking habits, and physical activity. The participants were selected using a stratified sampling method from adults residing in the five government-controlled municipalities of the Republic of Cyprus. The study included 1137 adults with a mean age of 40⋅8 years, of whom 26 % had multimorbidity. Individuals with multimorbidity consumed higher levels of sodium (P = 0⋅009) and vitamin A (P = 0⋅010) compared to those without multimorbidity. Additionally, higher fibre and sodium intake were also observed in individuals with at least one chronic disease of the circulatory system or endocrine system, compared to those with no chronic diseases in these systems (P < 0⋅05). Logistic regression models revealed that individuals with ≥2 chronic diseases compared to 0 or 1 chronic disease had higher fat intake (OR = 1⋅06, 95 % CI: 1⋅02, 1⋅10), higher iron intake (OR = 1⋅05, 95 % CI: 1⋅01, 1⋅09), lower mono-unsaturated fat intake (OR = 0⋅91, 95 % CI: 0⋅86, 0⋅96), and lower zinc intake (OR = 0⋅98, 95 % CI: 0⋅96, 0⋅99). Future research should replicate these results to further explore the intricate relationships between nutrient intake and multimorbidity. Our study's findings suggest that specific dietary components may contribute to preventing and managing multimorbidity.

尽管有大量研究调查了饮食与个体慢性疾病之间的关系,但关于饮食与多重疾病之间联系的研究很少。本研究探讨了饮食摄入宏量营养素和微量营养素与塞浦路斯成人多病的关系。该研究是一项横断面研究,在2018年5月至2019年6月期间使用标准化问卷收集数据。调查问卷包括社会人口统计信息、人体测量、病史、饮食习惯、睡眠质量、吸烟习惯和体育活动。参与者采用分层抽样方法从居住在塞浦路斯共和国五个政府控制的城市的成年人中选出。研究对象为1137名平均年龄为40⋅8岁的成年人,其中26%患有多重疾病。与没有多重疾病的人相比,患有多重疾病的人摄入了更高水平的钠(P = 0.009)和维生素A (P = 0.010)。此外,与没有慢性循环系统或内分泌系统疾病的人相比,至少有一种慢性循环系统或内分泌系统疾病的人的纤维和钠摄入量也更高(P < 0.05)。Logistic回归模型显示,与患有1种或2种慢性病的个体相比,患有2种或1种慢性病的个体具有较高的脂肪摄入量(or = 1⋅06,95% CI: 1⋅02,1⋅10)、较高的铁摄入量(or = 1⋅05,95% CI: 1⋅01,1⋅09)、较低的单不饱和脂肪摄入量(or = 0⋅91,95% CI: 0⋅86,0⋅96)和较低的锌摄入量(or = 0⋅98,95% CI: 0⋅96,0⋅99)。未来的研究应该重复这些结果,以进一步探索营养摄入与多发病之间的复杂关系。我们的研究结果表明,特定的饮食成分可能有助于预防和控制多重疾病。
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引用次数: 0
Association between micronutrients intake and metabolic-associated fatty liver disease: a cross-sectional study based on the National Health and Nutrition Examination Survey. 微量营养素摄入与代谢相关脂肪性肝病之间的关系:基于国家健康和营养检查调查的横断面研究
IF 2.5 Q3 NUTRITION & DIETETICS Pub Date : 2023-11-24 eCollection Date: 2023-01-01 DOI: 10.1017/jns.2023.99
Jun-Zhen Hou, Qi-Wei Wu, Li Zhang

Metabolic-associated fatty liver disease (MAFLD) has been proposed to replace the term non-alcoholic fatty liver disease (NAFLD) in 2020. The association between micronutrients and MAFLD has not been reported. Therefore, this study aims to explore the association between micronutrients intake and MAFLD. This was a cross-section study based on the National Health and Nutrition Examination Survey (NHANES). The dietary intake of copper, zinc, iron, and selenium was evaluated using the 24-h dietary recall interview. Logistic regression analysis was used to explore the association between micronutrients and MAFLD, and the results were shown as odds ratio (OR) with 95 % confidence intervals (CIs). A total of 5976 participants were finally included for analysis, with 3437 participants in the MAFLD group. After adjusting potential confounders, copper intake at quartile Q3 (OR = 0⋅68, 95 % CI 0⋅50, 0⋅93) and Q4 (OR = 0⋅60, 95 % CI 0⋅45, 0⋅80) was found to be associated with lower odds of MAFLD. Iron intake at Q2 (OR = 0⋅64, 95 % CI 0⋅45, 0⋅92) and Q3 (OR = 0⋅61, 95 % CI 0⋅41, 0⋅91) was associated with the lower odds of MAFLD. Our findings found that high intake of copper and adequate intake of iron were associated with MAFLD, which may provide guidance for the management of MAFLD.

代谢相关脂肪性肝病(MAFLD)已被提议在2020年取代非酒精性脂肪性肝病(NAFLD)。微量营养素与mald之间的关系尚未见报道。因此,本研究旨在探讨微量营养素摄入与MAFLD之间的关系。这是一项基于国家健康和营养检查调查(NHANES)的横断面研究。采用24小时饮食回忆访谈法评估膳食中铜、锌、铁和硒的摄入量。采用Logistic回归分析探讨微量营养素与MAFLD之间的关系,结果显示为95%置信区间(ci)的比值比(OR)。最终共纳入5976名参与者进行分析,其中3437名参与者为MAFLD组。在调整潜在混杂因素后,发现四分位Q3 (OR = 0⋅68,95% CI 0⋅50,0⋅93)和Q4 (OR = 0⋅60,95% CI 0⋅45,0⋅80)的铜摄入量与较低的MAFLD发生率相关。Q2 (OR = 0⋅64,95% CI 0⋅45,0⋅92)和Q3 (OR = 0⋅61,95% CI 0⋅41,0⋅91)的铁摄入量与较低的MAFLD发生率相关。我们的研究结果发现,高铜摄入量和足够的铁摄入量与MAFLD有关,这可能为MAFLD的管理提供指导。
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引用次数: 0
Risk factors associated with overweight and obesity in people with severe mental illness in South Asia: cross-sectional study in Bangladesh, India, and Pakistan. 南亚严重精神疾病患者超重和肥胖相关的危险因素:孟加拉国、印度和巴基斯坦的横断面研究
IF 2.5 Q3 NUTRITION & DIETETICS Pub Date : 2023-11-21 eCollection Date: 2023-01-01 DOI: 10.1017/jns.2023.100
Koralagamage Kavindu Appuhamy, Danielle Podmore, Alex Mitchell, Helal Uddin Ahmed, Mark Ashworth, Jan R Boehnke, Virtu Chongtham, Asiful Haidar Chowdhury, Olga P Garcia, Richard I G Holt, Rumana Huque, Krishna Prasad Muliyala, Eline Klein Onstenk, Sukanya Rajan, David Shiers, Najma Siddiqi, S Manjunatha, Gerardo A Zavala

Obesity is one of the major contributors to the excess mortality seen in people with severe mental illness (SMI) and in low- and middle-income countries people with SMI may be at an even greater risk. In this study, we aimed to determine the prevalence of obesity and overweight in people with SMI and investigate the association of obesity and overweight with sociodemographic variables, other physical comorbidities, and health-risk behaviours. This was a multi-country cross-sectional survey study where data were collected from 3989 adults with SMI from three specialist mental health institutions in Bangladesh, India, and Pakistan. The prevalence of overweight and obesity was estimated using Asian BMI thresholds. Multinomial regression models were then used to explore associations between overweight and obesity with various potential determinants. There was a high prevalence of overweight (17·3 %) and obesity (46·2 %). The relative risk of having obesity (compared to normal weight) was double in women (RRR = 2·04) compared with men. Participants who met the WHO recommendations for fruit and vegetable intake had 2·53 (95 % CI: 1·65-3·88) times greater risk of having obesity compared to those not meeting them. Also, the relative risk of having obesity in people with hypertension is 69 % higher than in people without hypertension (RRR = 1·69). In conclusion, obesity is highly prevalent in SMI and associated with chronic disease. The complex relationship between diet and risk of obesity was also highlighted. People with SMI and obesity could benefit from screening for non-communicable diseases, better nutritional education, and context-appropriate lifestyle interventions.

肥胖是严重精神疾病(SMI)患者死亡率过高的主要原因之一,在低收入和中等收入国家,重度精神疾病患者的风险可能更大。在这项研究中,我们旨在确定重度精神障碍患者中肥胖和超重的患病率,并调查肥胖和超重与社会人口统计学变量、其他身体合并症和健康风险行为的关系。这是一项多国横断面调查研究,收集了来自孟加拉国、印度和巴基斯坦三家专业精神卫生机构的3989名重度精神障碍成年人的数据。使用亚洲BMI阈值估计超重和肥胖的患病率。然后使用多项回归模型来探索超重和肥胖与各种潜在决定因素之间的关系。超重(17.3%)和肥胖(46.2%)的发生率较高。女性肥胖的相对风险(与正常体重相比)是男性的两倍(RRR = 2.04)。符合世界卫生组织水果和蔬菜摄入量建议的参与者患肥胖症的风险是不符合建议的参与者的2.53倍(95% CI: 1.65 - 3.88)。高血压患者发生肥胖的相对危险度比无高血压患者高69% (RRR = 1.69)。总之,肥胖在重度精神病人中非常普遍,并且与慢性疾病有关。饮食和肥胖风险之间的复杂关系也得到了强调。重度精神障碍患者和肥胖症患者可以从非传染性疾病筛查、更好的营养教育和适合具体情况的生活方式干预措施中受益。
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Journal of Nutritional Science
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