Research in Social & Administrative Pharmacy最新文献

英文中文

Health Belief Model Interventions in Pre-exposure Prophylaxis (PrEP): Untapped intervention in the pharmacy arena 健康信念模型干预暴露前预防（PrEP）：未开发的干预在药房领域。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-09-25 DOI: 10.1016/j.sapharm.2025.09.005

Alina Cernasev , Holly Angell , Karen Derefinko , Santosh Kumar , Theodore Cory

The human immunodeficiency virus (HIV) epidemic continues to be a major public health crisis in the United States. Although pre-exposure prophylaxis (PrEP) has emerged as an effective tool to prevent HIV transmission, its uptake and adherence remain suboptimal, especially among high-risk populations. This article explores how the Health Belief Model (HBM) can serve as a guiding framework for pharmacists and other healthcare professionals to enhance PrEP delivery and patient engagement.

Recent literature highlights persistent barriers to PrEP use, including stigma, perceived risk, misinformation, and healthcare access challenges. The five core components of the HBM—perceived severity, perceived susceptibility, perceived benefits, perceived barriers, and cues to action—have been used to understand and design interventions across multiple health behaviors. Studies suggest these components are useful in explaining patient behavior and provider limitations around PrEP, particularly in marginalized communities. While few studies directly apply HBM to PrEP adherence, evidence from related fields supports its predictive power.

The HBM offers a promising lens through which pharmacy-based interventions can be developed to address patient beliefs, reduce stigma, and increase PrEP uptake and adherence. Pharmacists, given their accessibility and trusted role in the community, are uniquely positioned to lead these efforts. Incorporating culturally responsive, HBM-informed strategies in pharmacy practice can significantly improve health outcomes in populations most affected by HIV.

人类免疫缺陷病毒（HIV）的流行仍然是美国主要的公共卫生危机。虽然暴露前预防（PrEP）已成为预防艾滋病毒传播的有效工具，但其吸收和坚持性仍然不理想，特别是在高危人群中。本文探讨了健康信念模型（HBM）如何作为药剂师和其他医疗保健专业人员的指导框架，以加强PrEP的交付和患者的参与。最近的文献强调了PrEP使用的持续障碍，包括耻辱，感知风险，错误信息和医疗保健获取挑战。hbm的五个核心组成部分——感知严重性、感知易感性、感知益处、感知障碍和行动线索——已被用于理解和设计跨多种健康行为的干预措施。研究表明，这些成分有助于解释PrEP的患者行为和提供者限制，特别是在边缘化社区。虽然很少有研究直接将HBM应用于PrEP依从性，但相关领域的证据支持其预测能力。HBM提供了一个有希望的视角，通过它可以开发基于药物的干预措施，以解决患者的信念，减少耻辱感，并增加PrEP的吸收和依从性。鉴于药剂师在社区中的可及性和可信赖的作用，他们在领导这些努力方面处于独特的地位。在药房实践中纳入文化响应和hbm知情战略可以显著改善受艾滋病毒影响最严重人群的健康结果。

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引用次数: 0

From global standards to local realities: Understanding the Granada Statements in pharmacy practice research 从全球标准到当地现实：理解格拉纳达声明在药学实践研究。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-09-16 DOI: 10.1016/j.sapharm.2025.09.004

Gizem Gülpınar , Aysel Pehlivanlı , Zaheer-Ud-Din Babar

Introduction

The Granada Statements were developed to improve the quality and visibility of pharmacy practice research by encouraging consistency in reporting. However, little is known about how these guidelines are interpreted in low- and middle-income countries (LMICs), where professional roles and services may differ. Examining these perspectives can highlight both barriers and opportunities for wider uptake.

Aim

This study explored how clinical and social pharmacy researchers perceive the Granada Statements, focusing on the challenges, enablers, and strategies that could enhance their application in resource-limited contexts.

Method

A qualitative design was adopted, using focus group discussions with researchers in Türkiye. Data were thematically analyzed through collaborative coding and interpretation. Special attention was given to the Statements’ key areas, including terminology, journal selection, perceptions of relevance, and proposed improvements.

Results

Participants regarded the Statements as a useful framework for clarifying expectations, promoting consistency, and stimulating dialogue about research quality. Barriers included difficulties applying standardized terminology in evolving service contexts, challenges in translating technical terms, undervaluation of LMIC research, financial constraints in open access publishing, and discouraging peer review experiences. Suggested enablers included templates, illustrative examples, modular adoption, culturally sensitive glossaries, and training with editors. A global classification framework for benchmarking pharmacy practice was also proposed.

Conclusion

This study shows that the Granada Statements have the potential to act not only as reporting guidance but also as a framework for more intentional, theory-driven, and globally relevant pharmacy practice research. Flexibility, contextual sensitivity, and institutional support are key to achieving this vision.

格拉纳达声明的制定是为了通过鼓励报告的一致性来提高药学实践研究的质量和可见性。然而，对于低收入和中等收入国家（LMICs）如何解释这些指南，人们知之甚少，这些国家的专业角色和服务可能有所不同。检查这些观点可以突出更广泛采用的障碍和机会。目的：本研究探讨临床和社会药学研究人员如何看待格拉纳达声明，重点关注在资源有限的情况下可以加强其应用的挑战、推动因素和策略。方法：采用定性设计，与 rkiye研究人员进行焦点小组讨论。通过协作编码和解释对数据进行主题分析。特别注意了《声明》的关键领域，包括术语、期刊选择、对相关性的认识和建议的改进。结果：与会者认为《声明》是澄清期望、促进一致性和促进关于研究质量的对话的有用框架。障碍包括在不断发展的服务环境中应用标准化术语的困难、翻译技术术语的挑战、对低收入和中等收入国家研究的低估、开放获取出版的财政限制以及不鼓励同行评议经验。建议的支持因素包括模板、说明性示例、模块化采用、具有文化敏感性的词汇表和编辑培训。同时，提出了一个全球性的药学实践基准分类框架。结论：本研究表明，格拉纳达声明不仅可以作为报告指南，还可以作为更有针对性的、理论驱动的、全球相关的药学实践研究的框架。灵活性、环境敏感性和机构支持是实现这一愿景的关键。

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引用次数: 0

Common ailment and non-prescription medication-related problems faced by people with intellectual disability: Findings from medication reviews provided by pharmacists 智力残疾者面临的常见疾病和非处方药相关问题；药剂师提供的药物审查结果。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-09-13 DOI: 10.1016/j.sapharm.2025.09.001

Chelsea Felkai , Jamie-Lee Carew , David Newby , Joyce Cooper , Hayley Croft

Background

Pharmacists in Australia play a significant role in managing non-prescription medicines and common ailments. The aims of this research were to describe the medication related issues people with intellectual disability face with their common ailments and non-prescription medications and document the recommendations made by pharmacists as part of the medication review process.

Method

A retrospective analysis of medication review reports from credentialed pharmacists performed for a person with intellectual disability between January 2020 and January 2024.

Results

A total of 80 reports were analysed with an average of 6.6 common ailments and 8.0 non-prescription medications per individual with ID. The credentialed pharmacists identified an average of 3.6 issues related to their common ailment or non-prescription medication.

Conclusion

People with intellectual disability have significant issues managing common ailments and non-prescription medicines, that could potentially be more appropriately managed in the primary care setting.

背景：澳大利亚的药剂师在管理非处方药和常见疾病方面发挥着重要作用。本研究的目的是描述智障患者在常见疾病和非处方药方面面临的药物相关问题，并记录药剂师在药物审查过程中提出的建议。方法：回顾性分析2020年1月至2024年1月间执业药师对1例智障患者的药物评价报告。结果：共分析了80份报告，平均每个ID患者6.6种常见疾病和8.0种非处方药。有资格的药剂师平均发现了3.6个与他们的常见病或非处方药有关的问题。结论：智障人士在处理常见病和非处方药方面存在重大问题，这些问题可能在初级保健机构得到更适当的管理。

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引用次数: 0

Development and psychometric evaluation of knowledge, attitude, and behavior questionnaire on fall risk–increasing drugs (KABQ-FRID) 增加跌倒风险药物知识、态度和行为问卷（KABQ-FRID）的编制及心理测量学评价。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-09-07 DOI: 10.1016/j.sapharm.2025.08.013

Laksmi Maharani , Adi Yugatama , Dedik Sulistiawan , Shu-Chun Lee

Background

Fall risk–increasing drugs (FRIDs) increase the risks of falls, injuries, and fractures among older adults. However, limited evidence exists on how older adults perceive and manage FRID use, particularly in Indonesia.

Objective

This study developed and psychometrically evaluated a questionnaire for assessing knowledge, attitudes, and behaviors (KABs) related to FRID use (hereafter KABQ-FRID) among older adults.

Methods

KABQ-FRID was developed through a three-stage process. The first stage involved defining a conceptual framework and generating items based on a literature review, team discussions, and expert meeting. The second stage included an expert panel review and assessment of face validity. The third stage involved psychometric testing with 100 older adults receiving medications from a public health center in Surakarta City, Indonesia. Data analysis included Mokken scale analysis, confirmatory factor analysis (CFA), construct validity assessment, and reliability testing.

Results

The final KABQ-FRID comprised 21 items across 3 dimensions: knowledge (7 items), attitude (5 items), and behavior (9 items). Psychometric evaluation demonstrated acceptable scalability for all items (Loevinger's H ≥ 0.30) and strong reliability (Cronbach's α > 0.7; intraclass correlation coefficient >0.9). CFA results revealed a χ²/df of 2.0, suggesting a reasonable model fit; all dimensions exhibited satisfactory loadings. Construct validity testing demonstrated strong convergent validity; 90.5 % of the items had a correlation coefficient of >0.4, and 100 % of the items had stronger correlations within their dimensions than with other constructs.

Conclusion

KABQ-FRID is a reliable and valid instrument for assessing KAB related to FRID use among community-dwelling older adults.

背景：增加跌倒风险的药物（frid）会增加老年人跌倒、受伤和骨折的风险。然而，关于老年人如何看待和管理FRID使用的证据有限，特别是在印度尼西亚。目的：本研究编制了一份问卷，用于评估老年人与FRID使用（以下简称KABQ-FRID）相关的知识、态度和行为（kab），并对其进行心理测量学评估。方法：KABQ-FRID的研制分为三个阶段。第一阶段包括定义一个概念框架，并根据文献回顾、团队讨论和专家会议生成项目。第二阶段包括专家小组评审和人脸效度评估。第三阶段涉及对100名老年人进行心理测试，这些老年人从印度尼西亚苏拉arta市的一家公共卫生中心接受药物治疗。数据分析包括Mokken量表分析、验证性因子分析（CFA）、构念效度评估和信度检验。结果：最终的KABQ-FRID包括知识（7项）、态度（5项）和行为（9项）3个维度的21个项目。心理测量评估显示，所有项目的可扩展性均可接受（Loevinger's H≥0.30），可靠性强（Cronbach's α > 0.7；类内相关系数>0.9）。CFA结果显示χ2/df为2.0，表明模型拟合合理；所有尺寸均表现出令人满意的载荷。构念效度检验显示出较强的收敛效度；90.5%的题项的相关系数为bb0.5, 100%的题项在其维度内的相关系数高于与其他构念的相关系数。结论：KABQ-FRID是评估社区老年人与FRID使用相关的KAB的可靠和有效的工具。

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引用次数: 0

Pilot of a pharmacist-delivered habit-based intervention to support medication adherence in primary care 药剂师提供的以习惯为基础的干预试验，以支持初级保健中的药物依从性。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-09-06 DOI: 10.1016/j.sapharm.2025.09.003

Matthew Witry , James Hoehns , L. Alison Phillips

Purpose

Informed by the Extended Common Sense Model, this study aimed to pilot a pharmacist-led intervention to promote medication adherence through habit formation compared to standard education.

Procedures

Patients new to medication were recruited in two phases. During Phase 1, the pharmacist provided standard education (control). In Phase 2, the pharmacist added a habit-formation component by completing a habit worksheet with patients. Surveys measuring medication beliefs, habit strength, and adherence were completed at baseline and 100 days later. Cues from the habit worksheets were coded and analyzed.

Findings

The habit intervention group (N = 17) showed no significant difference from the control group (N = 16) in medication-taking habit strength (p = 0.37) or self-reported adherence (MARS-5) (p = 0.47) at follow-up. Habit strength was the only significant predictor of adherence (MARS-5)(p = 0.02), while necessity beliefs predicted missed doses (p = 0.03).

Conclusion

High levels of habit strength and adherence may result from high baseline adherence levels. Further research should target patients with known non-adherence or without established medication routines.

Clinical trial

# NCT06230978.

目的：根据扩展常识模型，本研究旨在试点药剂师主导的干预措施，与标准教育相比，通过养成习惯来促进药物依从性。程序：分两个阶段招募新用药患者。在第一阶段，药剂师提供标准教育（对照）。在第二阶段，药剂师通过与患者一起完成习惯工作表来增加习惯形成的成分。测量用药信念、习惯强度和依从性的调查在基线和100天后完成。习惯工作表中的提示被编码和分析。结果：随访时，习惯干预组（N = 17）与对照组（N = 16）在服药习惯强度（p = 0.37）、自我报告依从性（MARS-5）（p = 0.47）方面均无显著差异。习惯强度是依从性的唯一显著预测因子（MARS-5）（p = 0.02），而必要性信念预测错过剂量（p = 0.03）。结论：高水平的习惯强度和依从性可能源于高基线依从性水平。进一步的研究应针对已知的不依从性或没有既定药物常规的患者。临床试验：# NCT06230978。

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引用次数: 0

Contributing factors of pediatric medication errors involving high-alert medications: A qualitative content analysis of self-reported medication safety incidents 涉及高警惕性药物的儿科用药差错的影响因素：自我报告用药安全事件的定性内容分析

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-09-05 DOI: 10.1016/j.sapharm.2025.09.002

Sini Kuitunen , Mari Saksa , Anna-Riia Holmström

Background

High-alert medications can cause severe medication errors (MEs) in pediatrics. A comprehensive understanding of the factors contributing to errors is needed to establish risk management actions.

Objective

To analyze incident reports involving high-alert medications and describe the contributing factors (CFs) of MEs in pediatrics.

Methods

A retrospective document analysis study utilizing an abductive qualitative content analysis of self-reported medication safety incidents concerning high-alert medications at a pediatric university hospital from 2018 to 2020. Incident reports (n = 426) were first subjected to an inductive qualitative content analysis to identify and categorize CFs, then quantified by frequencies and percentages, and ultimately deductively categorized based on the elements of the Systems Engineering Initiative for Patient Safety (SEIPS) model. The analysis was first conducted by one independent researcher, then reviewed by a second researcher, and later reviewed by the entire research group.

Results

A total of 933 CFs were identified, concerning 85.0 % (n = 362/426) of the incident reports. The most common main categories of CFs pertained to verifying the correct drug (11.1 %; n = 104/933), medications and pharmaceuticals (10.6 %; n = 99/933), and resourcing (10.5 %; n = 98/933). Over half of the CFs were linked to SEIPS elements involving tasks (39.6 %, n = 370) and tools and technologies (20.8 %, n = 194).

Conclusions

The CFs of pediatric MEs involving high-alert medications are multifaceted and have a wide impact on the entire system design, from organizational strategies to individual tasks. Risk management actions and further studies addressing pediatric-specific challenges are required to ensure the most optimal systemic defenses, enabling proactive monitoring error-provoking conditions in clinical practice.

背景：高警惕性药物可导致儿科严重用药错误（MEs）。建立风险管理行动需要全面了解导致错误的因素。目的：分析涉及高危药物的儿科MEs事件报告，并描述其影响因素（CFs）。方法：采用回溯性文献分析方法，对某儿科大学附属医院2018 - 2020年高危药物自述用药安全事件进行定性内容分析。事件报告（n = 426）首先进行归纳定性内容分析，以识别和分类CFs，然后根据频率和百分比进行量化，最终根据患者安全系统工程倡议（SEIPS）模型的要素进行演绎分类。该分析首先由一名独立研究人员进行，然后由另一名研究人员进行审查，后来由整个研究小组进行审查。结果：共发现CFs 933例，占事件报告的85.0% （n = 362/426）。最常见的CFs主要类别与验证正确的药物（11.1%,n = 104/933）、药物和药品（10.6%,n = 99/933）和资源（10.5%,n = 98/933）有关。超过一半的cf与涉及任务（39.6%,n = 370）和工具和技术（20.8%,n = 194）的SEIPS要素相关。结论：涉及高警惕性药物的儿科MEs的CFs是多方面的，对整个系统设计具有广泛的影响，从组织策略到个人任务。风险管理行动和针对儿科特定挑战的进一步研究需要确保最优的系统防御，从而在临床实践中主动监测引起错误的条件。

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