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Drug use patterns and health problems among people who use drugs in Guinea-Bissau (2022): A cross-sectional survey using respondent-driven sampling 几内亚比绍吸毒者的吸毒模式和健康问题(2022 年):采用受访者驱动抽样的横断面调查。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2024-11-09 DOI: 10.1016/j.drugpo.2024.104648
Andrew Scheibe , Andreia Teixeira , Mamadu Aliu Djaló , Miriam Nascimento Pereira , Kátia Ribeiro Barreto , Ibrahima Ba , Lucia Bird , Jason Eligh

Background

Little data exists on the use of cocaine, methamphetamine, tramadol and heroin or related health conditions in Guinea Bissau. We aimed to estimate drug use practices and the prevalence of selected blood-borne infections, depression and population size estimates of people who use injectable drugs in Guinea-Bissau.

Methods

We used respondent-driven sampling to recruit adults who use injectable drugs in this cross sectional survey in three cities (Bissau, Bafatá and Gabú) between July and September 2022. Participants completed an interviewer administered survey enquiring about sociodemographic characteristics, drug use practices and mental health. Rapid diagnostic testing was done for HIV, hepatitis B surface antigen (HBsAg) and hepatitis C antibody (anti-HCV). Data was weighted in RDS-Analyst using self-reported network size and Gile's Sequential Sampling Estimator. Population size estimates were generated using the two point capture-recapture method.

Results

Overall, 750 participants were recruited. People who use drugs were estimated to be mostly unemployed males aged between 25 and 49 years. Methamphetamine and crack cocaine were most commonly used. Prevalence of ever injecting ranged from 6 % to 44 %. Between 44 % and 52 % of people experience symptoms of depression. Prevalence ranges from 1.9 % to 5.2 % for HIV, and 5.7–8.3 % for HBsAg and 0.42–0.66 % for anti-HCV. The population estimates of people who use injectable drugs were 1637 in Bissau, 1314 in Bafatá and 424 in Gabú.

Conclusion

Methamphetamine and crack cocaine are the most commonly used injectable drugs in Guinea-Bissau. Symptoms of depression are common among people who use drugs in the country. Access to evidence-based drug use treatment and harm reduction interventions that integrate mental health care services are needed to improve the health and wellbeing of people who use drugs in Guinea-Bissau.
背景:关于几内亚比绍的可卡因、甲基苯丙胺、曲马多和海洛因使用情况或相关健康状况的数据很少。我们的目的是估算几内亚比绍使用注射毒品者的吸毒习惯、部分血液传播感染的流行率、抑郁症和人口规模:2022 年 7 月至 9 月期间,我们在三个城市(比绍、巴法塔和加布)采用受访者驱动的抽样方法招募了使用注射毒品的成年人参与此次横断面调查。参与者完成了一项由访谈者主持的调查,内容涉及社会人口特征、吸毒习惯和心理健康。对艾滋病毒、乙型肝炎表面抗原(HBsAg)和丙型肝炎抗体(抗-HCV)进行了快速诊断检测。数据在 RDS-Analyst 中使用自我报告的网络规模和 Gile 序列抽样估计器进行加权。使用两点捕获-再捕获法对人群规模进行估算:总共招募了 750 名参与者。据估计,吸毒者多为失业男性,年龄在 25 至 49 岁之间。甲基苯丙胺和快克可卡因是最常用的毒品。曾经注射毒品的比例从 6% 到 44% 不等。44%到52%的人有抑郁症状。艾滋病毒感染率为 1.9 % 至 5.2 %,HBsAg 感染率为 5.7 % 至 8.3 %,抗-HCV 感染率为 0.42 % 至 0.66 %。据估计,使用注射毒品的人口比例分别为:比绍 1637 人,巴法塔 1314 人,加布 424 人:结论:甲基苯丙胺和快克可卡因是几内亚比绍最常用的注射毒品。该国的吸毒者普遍有抑郁症状。要改善几内亚比绍吸毒者的健康和福祉,就必须提供循证吸毒治疗和减少危害干预措施,并将心理保健服务纳入其中。
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引用次数: 0
Substance use as a public health issue: A critical review of the Canadian literature, 1896–2020 作为公共卫生问题的药物使用:对 1896-2020 年加拿大文献的批判性回顾。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2024-11-09 DOI: 10.1016/j.drugpo.2024.104634
Jean-François Crépault , Brian Emerson , Elaine Hyshka , Carol Strike , Robin Room , Jürgen Rehm
<div><h3>Background</h3><div>The risks associated with substance use can be framed in many ways. In Canada, the consumption of psychoactive substances has at various times been considered a moral, criminal, or medical issue. In the past decade, substance use has increasingly been framed as a public health issue. This study sought to trace the historical development and evolution of the concept of a public health approach to substance use in Canada through a critical review of the academic literature.</div></div><div><h3>Methods</h3><div>Critical review is a method designed to systematically search a body of literature, take stock of its evolution and current state, identify conceptual contributions, and compare schools of thought. Systematic searches were conducted in February and March 2023 in five English-language databases (CINAHL, Medline, PsycInfo, Scopus, Web of Science) and three French-language databases (Cairn.info, Érudit, SDM Repère). Eligible articles were written in English or French by a first author based in Canada, focused primarily on substance use, and published in 2020 or earlier.</div></div><div><h3>Results</h3><div>64 articles, published between 1896 and 2020, were synthesized. We found that while public health has been used as a framing for substance use in Canada for at least 120 years, what that means and what it implies for public policy has changed over time. During the first several decades covered in this review, we periodically see the emergence of new conceptualizations of the problem of substance use and its framing as a public health issue. For example, between the 1890s and 1980s, the dominant view of alcohol evolves from that of a social problem, to a disease, to a population health issue. In the 1990s we see the last of these paradigmatic shifts. From that point onwards, the dominant conceptualization is one that prioritizes drug policy harms over drug harms; correspondingly, proposed solutions center on harm reduction, regulation, and policy reform. Beginning in the 2000s, we see detailed proposals for a comprehensive public health framework to substance use, with authors setting out to define the premises, objectives, and components of such a framework.</div></div><div><h3>Conclusion</h3><div>Overall we found a gradual convergence towards a potential Canadian model for a public health approach to substance use: a model based on principles including human rights and equity, in which psychoactive substances are neither criminalized nor commercialized, but rather strictly regulated, proportionately to the risks they pose, in a manner that optimizes the health of the population. At present, governments across Canada appear to be moving in the opposite direction: drug policy is leaning further into criminalization for already illicit substances and further into commercialization for legal ones. Treating psychoactive substances as either the objects of criminal law or as harmless commodities are both associated with
背景:与药物使用相关的风险可以有多种说法。在加拿大,精神活性物质的消费在不同时期被视为道德、犯罪或医疗问题。在过去十年中,药物使用越来越多地被视为一个公共卫生问题。本研究试图通过对学术文献的批判性评述,追溯加拿大以公共卫生方法处理药物使用问题这一概念的历史发展和演变过程:批判性综述是一种方法,旨在系统地搜索文献,总结其演变和现状,确定概念贡献,并比较思想流派。我们于 2023 年 2 月至 3 月在五个英文数据库(CINAHL、Medline、PsycInfo、Scopus、Web of Science)和三个法文数据库(Cairn.info、Érudit、SDM Repère)中进行了系统检索。符合条件的文章均以英语或法语撰写,第一作者居住在加拿大,主要关注药物使用问题,发表于 2020 年或更早:结果:我们对 1896 年至 2020 年间发表的 64 篇文章进行了综述。我们发现,虽然公共卫生在加拿大被用作药物使用的框架已有至少 120 年的历史,但其含义及其对公共政策的影响却随着时间的推移而发生了变化。在本综述所涵盖的前几十年中,我们定期看到对药物使用问题的新概念及其作为公共卫生问题的框架出现。例如,从 19 世纪 90 年代到 20 世纪 80 年代,对酒精的主流看法从社会问题发展到疾病,再到人口健康问题。20 世纪 90 年代,我们看到了最后一次范式转变。从那时起,占主导地位的概念是将毒品政策危害置于毒品危害之上;相应地,提出的解决方案以减少危害、监管和政策改革为中心。从 2000 年代开始,我们看到了针对药物使用的全面公共卫生框架的详细建议,作者们开始界定这一框架的前提、目标和组成部分:总之,我们发现加拿大对药物使用的公共卫生方法逐渐趋向于一种潜在的模式:一种基于人权和公平等原则的模式,在这种模式中,精神活性物质既不被定罪,也不被商业化,而是根据其造成的风险进行严格监管,以优化人口的健康。目前,加拿大各地政府似乎正朝着相反的方向发展:毒品政策正进一步向非法药物的刑事犯罪化和合法药物的商业化靠拢。将精神活性物质视为刑法对象或无害商品都会造成伤害。公共卫生部门有责任证明有危害较小的替代品。
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引用次数: 0
Creating a robust coordinated data and policy framework for addressing substance use issues in the United States 为解决美国的药物使用问题创建一个强大的数据和政策协调框架
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2024-11-06 DOI: 10.1016/j.drugpo.2024.104629
Qiushi Chen , Glenn Sterner , Danielle Rhubart , Robert Newton , Bethany Shaw , Dennis Scanlon
The ongoing opioid epidemic has been met with the inadequate use of data-informed approaches to respond to the crisis. Although data relevant to opioid and substance use do exist and have been utilized for research in the literature and practice, they have not been prepared for cross-sector coordination and for providing practical intelligence to inform policy planning directly. In this article, we share our views on how data can better serve the purposes of informing policy and planning to maximize population health and safety benefits. Based on our experience in advising state policymakers on developing settlement allocation strategies based on empirical data, we discuss several issues in the data, including coverage, specificity in drug types, time relevance, geographic units, and access, which may hinder data-informed policymaking. Following these discussions, we envision a coordinated data and policy framework as an ideal case to ensure access to meaningful and timely data and harness the full potential of the data to inform policy to combat the continuing epidemic.
在阿片类药物持续流行的情况下,没有充分使用以数据为依据的方法来应对危机。虽然确实存在与阿片类药物和药物使用相关的数据,而且这些数据已被用于文献研究和实践,但这些数据尚未准备好用于跨部门协调和提供实用情报,以便直接为政策规划提供信息。在本文中,我们将就数据如何更好地为政策和规划提供信息,以最大限度地提高人口健康和安全效益分享我们的观点。根据我们为各州政策制定者提供建议,帮助其根据经验数据制定结算分配策略的经验,我们讨论了数据中的几个问题,包括覆盖范围、药物类型的特殊性、时间相关性、地理单元和获取途径,这些问题可能会阻碍以数据为依据的政策制定。在这些讨论之后,我们设想建立一个协调的数据和政策框架,作为一个理想的案例,以确保获得有意义和及时的数据,并充分发挥数据的潜力,为制定政策提供信息,以应对持续蔓延的疫情。
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引用次数: 0
Uncorking the ‘wine mum’: Exploring the complexity of Australian women's everyday lives and drinking practices 揭开 "葡萄酒妈妈 "的神秘面纱:探索澳大利亚妇女日常生活和饮酒习惯的复杂性
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2024-11-05 DOI: 10.1016/j.drugpo.2024.104637
Gabriel Caluzzi , Megan Cook , Maree Patsouras , Cassandra J.C. Wright , Emmanuel Kuntsche , Sandra Kuntsche

Background

With greater attention given to midlife women's drinking in research and in media representations of ‘wine mums’, we suggest that focusing on static gender roles (e.g., women as mothers) risks overlooking complex and dynamic features of women's lives. We draw on the concept of thick intersectionality to explore how everyday experiences of women's lives and multiple identities shape their drinking practices.

Methods

This study draws on interviews with Australian women in their forties and fifties who were employed, had school-aged children and drank alcohol. We present four detailed accounts as interpreted narratives.

Results

Close analysis of the stories of four women highlights important features of women's lives. Drinking practices were often intertwined with gendered labour, power inequalities and managing stresses borne from these. Gender, class, relationality, life course transitions, affect and various aspects of labour dynamics (temporality, autonomy and unseen labour) were prominent in the accounts. Alongside this health, geography, life histories and culture interacted in women's narratives and the various identities and roles they moved between, co-producing drinking practices in different ways.

Conclusion

By juxtaposing women's stories with ‘wine mum’ stereotypes, and the broader feminisation of drinking, we highlight how women's drinking practices are influenced not only by static identities, but the complex interplay between gender, a myriad of fluid social categories, and day-to-day life. We suggest that attending to context and women's everyday experiences is crucial for generating a nuanced understanding of drinking beyond women's traditional gender roles.
背景随着研究和媒体对 "酒妈妈 "的描述越来越关注中年女性的饮酒问题,我们认为,关注静态的性别角色(如作为母亲的女性)有可能会忽视女性生活中复杂和动态的特征。我们借鉴了 "厚交集"(thick intersectionality)的概念,来探讨女性的日常生活经验和多重身份是如何影响她们的饮酒习惯的。结果对四位妇女的故事进行仔细分析,突出了妇女生活的重要特征。饮酒习惯往往与性别劳动、权力不平等以及应对由此产生的压力交织在一起。性别、阶级、关系性、生命历程的转变、情感和劳动动态的各个方面(时间性、自主性和无形劳动)在叙述中都很突出。通过将妇女的故事与 "酒妈妈 "的刻板印象以及更广泛的饮酒女性化并列,我们强调了妇女的饮酒行为不仅受到静态身份的影响,而且还受到性别、无数流动的社会类别和日常生活之间复杂的相互作用的影响。我们认为,关注背景和女性的日常生活经验对于超越女性的传统性别角色,对饮酒产生细致入微的理解至关重要。
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引用次数: 0
High hepatitis C virus reinfection in a community-based sample of people who inject drugs in Imphal, India 印度英帕尔注射吸毒者社区样本中丙型肝炎病毒再感染率较高
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2024-11-04 DOI: 10.1016/j.drugpo.2024.104635
Mihili P. Gunaratne , Ashwini Kedar , Allison M. McFall , Aylur K. Srikrishnan , Shanta Chingtham , Pradeep Amrose , Jiban J. Baishya , Archit K. Sinha , Shruti H. Mehta , Sunil S. Solomon

Background

Reinfection with hepatitis C virus (HCV) following successful treatment with direct-acting antivirals (DAAs) is a threat to achieving the World Health Organization viral hepatitis elimination goals. Given the limited data among people who inject drugs (PWID) from low-and-middle-income countries (LMICs), we characterized HCV reinfection among PWID in Imphal, India.

Methods

Our study population included PWID who achieved a sustained virologic response (SVR) after DAA treatment at community-based treatment programs located in harm reduction centers. Reinfection rates per 100 person-years (PY) were calculated overall and by select characteristics. Poisson regression was used to estimate incidence rate ratios and correlates of reinfection.

Results

Among 1267 PWID who achieved SVR and were screened for this study, 315 instances of reinfection were documented over 2395 PY of follow-up with an incidence rate (IR) of 13.2 per 100 PY (95 % CI: 11.8, 14.7). The incidence of reinfection was highest among those 18–24 years old (20.0 per 100 PY, 95 % CI: 16.9, 23.8) and in multivariable analysis, age remained independently associated with reinfection risk. Those 18–24 years old had the highest incidence (adjusted incidence rate ratio (aIRR) compared to 45–54 years: 4.94 [95 % CI: 2.59, 9.42]). The use of medication for opioid use disorder (MOUD) was also associated with reinfection in those reporting recent injection (aIRR: 1.57 [95 % CI: 1.19, 2.09]).

Conclusions

The high reinfection rate among PWID in Imphal, a setting with comprehensive harm reduction programs, highlights the need to integrate and innovate models of HCV care and harm reduction service delivery with a particular emphasis on young PWID.
背景直接作用抗病毒药物(DAAs)治疗成功后丙型肝炎病毒(HCV)的再感染对实现世界卫生组织消除病毒性肝炎的目标构成威胁。鉴于中低收入国家(LMICs)注射吸毒者(PWID)中的数据有限,我们对印度英帕尔注射吸毒者中的丙型肝炎病毒再感染情况进行了研究。方法我们的研究对象包括在减低危害中心的社区治疗项目中接受 DAA 治疗后获得持续病毒学应答(SVR)的注射吸毒者。我们计算了每百人年 (PY) 的总体再感染率,并按特定特征进行了分类。结果在1267名获得SVR并接受筛查的PWID中,在2395个随访年中记录了315例再感染,再感染发生率(IR)为每100人年13.2例(95 % CI:11.8, 14.7)。18-24 岁人群的再感染率最高(20.0/100 PY,95 % CI:16.9, 23.8),在多变量分析中,年龄仍然与再感染风险独立相关。18-24 岁人群的发病率最高(与 45-54 岁人群相比,调整后发病率比(aIRR)为 4.94 [95 % ci]):4.94 [95 % CI: 2.59, 9.42])。结论英帕尔地区的PWID再感染率很高,这突出表明有必要整合和创新HCV护理和减低伤害服务的提供模式,尤其要重视年轻的PWID。
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引用次数: 0
Cannabis legalization and changes in cannabis and tobacco/nicotine use and co-use in a national cohort of U.S. adults during 2017–2021 大麻合法化与 2017-2021 年美国成年人全国队列中大麻和烟草/尼古丁使用及共同使用情况的变化
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2024-11-04 DOI: 10.1016/j.drugpo.2024.104618
Vira Pravosud , Stanton Glantz , Salomeh Keyhani , Pamela M. Ling , Lauren K. Lempert , Katherine J. Hoggatt , Deborah Hasin , Nhung Nguyen , Francis Julian L. Graham , Beth E. Cohen

Background

Little is known about whether cannabis legalization impacts cannabis use uptake or has spillover effects on co-use of cannabis and tobacco/nicotine (using both in the past 30 days). We determined associations of cannabis legalization with self-reported (1) current (past 30-day) cannabis use; (2) current (“now”) tobacco/nicotine use (smoking or electronic cigarette use); and (3) current co-use of cannabis and tobacco/nicotine and how prevalence is changing over time.

Methods

In this longitudinal study, a web-based survey was administered to a nationally representative, population-based panel of US adults in 2017, 2020, and 2021. We used weighted unadjusted binomial logistic GEE models to assess changes in prevalence of cannabis, tobacco/nicotine use and co-use and weighted, adjusted binary logistic GEE models to assess associations of cannabis legalization with cannabis, tobacco/nicotine use and co-use.

Results

A total of 9003 participants (age range = 18–94, mean age = 47.9 [±17.4 SD] years; 4696 females [weighted 52.0 %]) completed the survey in 2017; 5979/8529 (70.1 %) in 2020 and 5420/7305 (74.2 %) in 2021 from the original cohort who remained available. Current cannabis use significantly increased +3.3 % between 2017 and 2021, while tobacco/nicotine use significantly declined (−1.9 %); co-use of cannabis and tobacco/nicotine did not change significantly (+0.2 %). Both medical and recreational cannabis legalization was associated with increased current cannabis use; the independent effect of recreational cannabis legalization was 1.13 times larger than medical. There were no statistically significant differences in tobacco/nicotine use and co-use prevalence by legalization status.

Conclusion

Cannabis legalization increases cannabis use but is not associated with changes in tobacco/nicotine use or co-use. Legalization should be coupled with public health efforts.
背景关于大麻合法化是否会影响大麻使用的吸收或对大麻和烟草/尼古丁的共同使用(在过去 30 天内同时使用这两种物质)产生溢出效应,人们知之甚少。我们确定了大麻合法化与自我报告的(1)当前(过去 30 天)大麻使用情况;(2)当前("现在")烟草/尼古丁使用情况(吸烟或使用电子香烟);以及(3)当前大麻和烟草/尼古丁共同使用情况之间的关联,以及随着时间的推移流行率的变化情况。方法在这项纵向研究中,我们于 2017 年、2020 年和 2021 年对一个具有全国代表性、基于人口的美国成年人小组进行了基于网络的调查。我们使用加权未调整二项逻辑 GEE 模型来评估大麻、烟草/尼古丁使用和共同使用流行率的变化,并使用加权调整二项逻辑 GEE 模型来评估大麻合法化与大麻、烟草/尼古丁使用和共同使用的关联。结果 2017 年共有 9003 名参与者(年龄范围 = 18-94,平均年龄 = 47.9 [±17.4 SD] 岁;4696 名女性 [加权 52.0 %])完成了调查;2020 年有 5979/8529 人(70.1 %)完成了调查,2021 年有 5420/7305 人(74.2 %)完成了调查。2017 年至 2021 年期间,当前大麻使用率大幅上升 +3.3%,而烟草/尼古丁使用率则大幅下降(-1.9%);大麻和烟草/尼古丁的共同使用率变化不大(+0.2%)。医用大麻合法化和娱乐用大麻合法化都与当前大麻使用的增加有关;娱乐用大麻合法化的独立效应是医用大麻合法化的 1.13 倍。大麻合法化增加了大麻使用,但与烟草/尼古丁使用或共同使用的变化无关。大麻合法化应与公共卫生工作相结合。
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引用次数: 0
“They talk about it like it's an overdose crisis when in fact it's basically genocide”: The experiences of Indigenous peoples who use illicit drugs in Vancouver's Downtown Eastside neighbourhood "他们说得好像这是一场吸毒过量危机,而实际上这基本上是一场种族灭绝:温哥华市中心东区使用非法药物的原住民的经历
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2024-11-04 DOI: 10.1016/j.drugpo.2024.104631
Jennifer Lavalley , Linda Steinhauer , Dino (Boomer) Bundy , Thomas Kerr , Ryan McNeil
Indigenous Peoples who use illicit drugs (IPWUID) are disproportionately represented among toxic drug poisoning deaths in Canada. These drug-related harms are framed by the historical and ongoing trauma related to settler colonialism and are acutely visible in Vancouver, Canada's Downtown Eastside - a low-income neighbourhood that is an epicenter of the drug poisoning crisis and characterized by entrenched poverty, substance use, violence, and homelessness. This study was undertaken to examine the experiences and perspectives of IPWUID in the Downtown Eastside regarding the drug poisoning crisis and the responsiveness of harm reduction programs within the context of settler colonialism. Indigenous-led qualitative interviews were conducted with 16 IPWUID recruited by Indigenous peer researchers. Indigenous ways of knowing were embedded throughout the entire research design to ensure research was culturally congruent. Interview transcripts were analyzed thematically and interpreted by drawing on concepts of social violence and racial capitalism. Our analysis reviewed three key themes that centered the experiences of IPWUID in Vancouver's Downtown Eastside in relation to the drug poisoning crisis: (1) that the drug poisoning crisis is understood as a form of genocide toward Indigenous Peoples; (2) that the crisis is experienced within the context of pervasive distrust and adversarial relationships with police rooted in structurally racist experiences of place-based policing practices; and (3) that there is a desire for culturally-safe harm reduction care with Indigenous representation, cultural integration, and that addresses inequities and injustice stemming from colonialism and structural racism. Findings demonstrate how responses to the drug poisoning crisis among IPWUID need to respond to social and materials conditions perpetuated by colonialism and racial capitalism, while also centering IPWUID through the development and implementation of Indigenous-led and culturally safe harm reduction approaches.
在加拿大的有毒药物中毒死亡案例中,使用非法药物的原住民(IPWUID)所占比例过高。这些与毒品有关的伤害是由定居殖民主义相关的历史和持续创伤造成的,在加拿大温哥华的下城东区非常明显--这是一个低收入社区,是毒品中毒危机的中心,其特点是根深蒂固的贫困、药物使用、暴力和无家可归。本研究旨在考察下城东区 IPWUID 在定居者殖民主义背景下,对毒品中毒危机和减低伤害计划的反应方面的经验和观点。由原住民主导的定性访谈由原住民同行研究人员对招募的 16 名 IPWUID 进行。原住民的认知方式贯穿了整个研究设计,以确保研究与文化相一致。通过借鉴社会暴力和种族资本主义的概念,对访谈记录进行了专题分析和解释。我们的分析回顾了三个关键主题,它们集中反映了温哥华市中心东区 IPWUID 在毒品中毒危机中的经历:(1) 毒品中毒危机被理解为对土著人民的一种种族灭绝形式;(2) 该危机是在普遍存在的不信任和与警察的敌对关系的背景下经历的,而这种不信任和敌对关系植根于基于地方警务实践的结构性种族主义经验中;(3) 人们渴望获得具有土著代表性、文化融合的文化上安全的减低伤害护理,以解决源于殖民主义和结构性种族主义的不平等和不公正问题。研究结果表明,应对 IPWUID 毒品中毒危机需要应对殖民主义和种族资本主义造成的社会和物质条件,同时还要通过制定和实施由土著人主导的、文化上安全的减低伤害方法,以 IPWUID 为中心。
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引用次数: 0
Bridging the gap: Exploring consumer experiences and motivations for transitioning between illicit and regulated cannabis markets 缩小差距:探索消费者在非法和受管制大麻市场之间过渡的经历和动机。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2024-11-02 DOI: 10.1016/j.drugpo.2024.104644
Jennifer R. Donnan , Rachel Howells , Sylvia Farooq , Myles Maillet , Laura M. Harris-Lane

Background

Canada pioneered the non-medical legalization of cannabis production and sales, witnessing substantial growth in the regulated market over the last five years, post-legalization. However, persistent barriers hinder many consumers from transitioning to the legal market, necessitating a nuanced understanding of their behaviors for targeted policy interventions. This study aims to improve understanding of cannabis consumers’ unregulated purchase decisions in British Columbia (B.C.), and to explore motivational factors for transitioning to the legal market.

Methods

We conducted semi-structured interviews with cannabis consumers in B.C., who were at least 19 years old and purchased some or all of their cannabis through unregulated sources. Interviews were transcribed and an inductive thematic analysis was conducted using NVivo. Through coding iterations, we moved from descriptive to analytic codes, and finally mapped the codes to themes aligned with the Five Stages of Consumer Decision Making model.

Results

Participants (N = 31) represented a broad range of demographic characteristics (i.e., gender, age, education, income). Four themes were identified: seeking information, evaluation of alternatives, purchase decision, and post purchase evaluation. Despite purchasing all or some of their cannabis from the unregulated market, most participants were supportive of legalization and felt that legal cannabis is safe, accessible, and of reasonable quality. However, several barriers prevent consumers from regularly accessing the regulated market, including: price, lack of sales and promotions, potency, limited product variety, and inadequate product interaction.

Conclusion

This study delineates barriers that obstruct consumers' transition to the regulated market. These findings, aligned with considerations for public health and safety, offer valuable insights to inform cannabis policy and promote a more effective and consumer-oriented regulatory framework.
背景:加拿大开创了大麻生产和销售非医疗合法化的先河,在合法化后的过去五年里,受监管市场出现了大幅增长。然而,持续存在的障碍阻碍了许多消费者向合法市场过渡,因此有必要深入了解他们的行为,以便采取有针对性的政策干预措施。本研究旨在加深对不列颠哥伦比亚省(B.C.)大麻消费者不受管制的购买决策的了解,并探讨向合法市场过渡的动机因素:我们对不列颠哥伦比亚省的大麻消费者进行了半结构式访谈,这些消费者至少 19 岁,通过非管制渠道购买部分或全部大麻。我们对访谈内容进行了誊写,并使用 NVivo 进行了归纳式主题分析。通过编码迭代,我们从描述性编码转向分析性编码,最后将编码映射到与消费者决策五阶段模型相一致的主题上:参与者(N = 31)代表了广泛的人口特征(即性别、年龄、教育程度、收入)。确定了四个主题:寻求信息、评估替代品、购买决策和购买后评估。尽管大部分或部分大麻是从不受监管的市场上购买的,但大多数参与者都支持大麻合法化,并认为合法大麻安全、易获得且质量合理。然而,一些障碍阻碍了消费者经常进入受管制市场,其中包括:价格、缺乏销售和促销、效力、产品种类有限以及产品互动不足:本研究描述了阻碍消费者过渡到规范市场的障碍。这些研究结果与对公共健康和安全的考虑相一致,为制定大麻政策提供了有价值的见解,并促进了更加有效和以消费者为导向的监管框架。
{"title":"Bridging the gap: Exploring consumer experiences and motivations for transitioning between illicit and regulated cannabis markets","authors":"Jennifer R. Donnan ,&nbsp;Rachel Howells ,&nbsp;Sylvia Farooq ,&nbsp;Myles Maillet ,&nbsp;Laura M. Harris-Lane","doi":"10.1016/j.drugpo.2024.104644","DOIUrl":"10.1016/j.drugpo.2024.104644","url":null,"abstract":"<div><h3>Background</h3><div>Canada pioneered the non-medical legalization of cannabis production and sales, witnessing substantial growth in the regulated market over the last five years, post-legalization. However, persistent barriers hinder many consumers from transitioning to the legal market, necessitating a nuanced understanding of their behaviors for targeted policy interventions. This study aims to improve understanding of cannabis consumers’ unregulated purchase decisions in British Columbia (B.C.), and to explore motivational factors for transitioning to the legal market.</div></div><div><h3>Methods</h3><div>We conducted semi-structured interviews with cannabis consumers in B.C., who were at least 19 years old and purchased some or all of their cannabis through unregulated sources. Interviews were transcribed and an inductive thematic analysis was conducted using NVivo. Through coding iterations, we moved from descriptive to analytic codes, and finally mapped the codes to themes aligned with the <em>Five Stages of Consumer Decision Making</em> model.</div></div><div><h3>Results</h3><div>Participants (<em>N</em> = 31) represented a broad range of demographic characteristics (i.e., gender, age, education, income). Four themes were identified: seeking information, evaluation of alternatives, purchase decision, and post purchase evaluation. Despite purchasing all or some of their cannabis from the unregulated market, most participants were supportive of legalization and felt that legal cannabis is safe, accessible, and of reasonable quality. However, several barriers prevent consumers from regularly accessing the regulated market, including: price, lack of sales and promotions, potency, limited product variety, and inadequate product interaction.</div></div><div><h3>Conclusion</h3><div>This study delineates barriers that obstruct consumers' transition to the regulated market. These findings, aligned with considerations for public health and safety, offer valuable insights to inform cannabis policy and promote a more effective and consumer-oriented regulatory framework.</div></div>","PeriodicalId":48364,"journal":{"name":"International Journal of Drug Policy","volume":"134 ","pages":"Article 104644"},"PeriodicalIF":4.4,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A place-based spatial analysis of racial inequities in overdose in St. Louis County Missouri, United States 对美国密苏里州圣路易斯县用药过量的种族不平等现象进行基于地点的空间分析。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2024-11-02 DOI: 10.1016/j.drugpo.2024.104611
Phillip L. Marotta , Benjamin CB Leach , William D. Hutson , Joel M. Caplan , Brenna Lohmann , Charlin Hughes , Devin Banks , Stephen Roll , Yung Chun , Jason Jabbari , Rachel Ancona , Kristen Mueller , Ben Cooper , Theresa Anasti , Nathaniel Dell , Rachel Winograd , Robert Heimer

Objective

The objective of this study was to identify place features associated with increased risk of drug-involved fatalities and generate a composite score measuring risk based on the combined effects of features of the built environment.

Methods

We conducted a geospatial analysis of overdose data from 2022 to 2023 provided by the St. Louis County Medical Examiner's Office to test whether drug-involved deaths were more likely to occur near 54 different place features using Risk Terrain Modeling (RTM). RTM was used to identify features of the built environment that create settings of heightened overdose risk. Risk was estimated using Relative Risk Values (RRVs) and a composite score measuring Relative Risk Scores (RRS) across the county was produced for drugs, opioids, and stimulants, as well as by Black and White decedents.

Results

In the model including all drugs, deaths were more likely to occur in close proximity to hotels/motels (RRV=39.65, SE=0.34, t-value=10.81 p<.001), foreclosures (RRV=4.42, SE=0.12, t-value = 12.80, p<.001), police departments (RRV=3.13, SE=0.24, t-score=4.86, p<.001), and restaurants (RRV=2.33, SE=0.12, t-value=7.16, p<.001). For Black decedents, deaths were more likely to occur near foreclosures (RRV=9.01, SE=0.18, t-value =11.92, p<.001), and places of worship (RRV= 2.51, SE=0.18, t-value = 11.92, p<.001). For White decedents, deaths were more likely to occur in close proximity to hotels/motels (RRV=38.97, SE=0.39, t-value=9.30, p<.001) foreclosures (RRV=2.57, SE=0.16, t-value =5.84, p<.001), restaurants (RRV=2.52, SE=0.17, t-value=5.33, p<.001) and, auto painting/repair shops (RRV=0.04, SE=0.18, t-value =3.39, p<.001).

Conclusion

These findings suggest that places of worship, the hospitality industry, and housing authorities may be physical features of the environment that reflect social conditions that are conducive to overdose. The scaling up of harm reduction strategies could be enhanced by targeting places where features are co-located.
研究目的本研究的目的是确定与涉毒死亡风险增加相关的地点特征,并根据建筑环境特征的综合影响生成衡量风险的综合评分:我们对圣路易斯郡法医办公室提供的2022年至2023年吸毒过量数据进行了地理空间分析,利用风险地形模型(RTM)检验了54个不同地点的特征是否更有可能导致涉毒死亡。风险地形模型用于确定建筑环境中哪些地方会增加吸毒过量的风险。使用相对风险值(RRV)对风险进行估算,并针对毒品、阿片类药物和兴奋剂以及黑人和白人死者得出衡量全县相对风险分数(RRS)的综合分数:在包括所有毒品的模型中,死亡更有可能发生在酒店/旅馆附近(RRV=39.65,SE=0.34,t 值=10.81):这些研究结果表明,宗教场所、酒店业和住房当局可能是环境的物理特征,反映了有利于吸毒过量的社会条件。针对这些特征共存的场所,可以加强减少伤害战略的推广。
{"title":"A place-based spatial analysis of racial inequities in overdose in St. Louis County Missouri, United States","authors":"Phillip L. Marotta ,&nbsp;Benjamin CB Leach ,&nbsp;William D. Hutson ,&nbsp;Joel M. Caplan ,&nbsp;Brenna Lohmann ,&nbsp;Charlin Hughes ,&nbsp;Devin Banks ,&nbsp;Stephen Roll ,&nbsp;Yung Chun ,&nbsp;Jason Jabbari ,&nbsp;Rachel Ancona ,&nbsp;Kristen Mueller ,&nbsp;Ben Cooper ,&nbsp;Theresa Anasti ,&nbsp;Nathaniel Dell ,&nbsp;Rachel Winograd ,&nbsp;Robert Heimer","doi":"10.1016/j.drugpo.2024.104611","DOIUrl":"10.1016/j.drugpo.2024.104611","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this study was to identify place features associated with increased risk of drug-involved fatalities and generate a composite score measuring risk based on the combined effects of features of the built environment.</div></div><div><h3>Methods</h3><div>We conducted a geospatial analysis of overdose data from 2022 to 2023 provided by the St. Louis County Medical Examiner's Office to test whether drug-involved deaths were more likely to occur near 54 different place features using Risk Terrain Modeling (RTM). RTM was used to identify features of the built environment that create settings of heightened overdose risk. Risk was estimated using Relative Risk Values (RRVs) and a composite score measuring Relative Risk Scores (RRS) across the county was produced for drugs, opioids, and stimulants, as well as by Black and White decedents.</div></div><div><h3>Results</h3><div>In the model including all drugs, deaths were more likely to occur in close proximity to hotels/motels (RRV=39.65, SE=0.34, t-value=10.81 <em>p</em>&lt;.001), foreclosures (RRV=4.42, SE=0.12, t-value = 12.80, <em>p</em>&lt;.001), police departments (RRV=3.13, SE=0.24, t-score=4.86, <em>p</em>&lt;.001), and restaurants (RRV=2.33, SE=0.12, t-value=7.16, <em>p</em>&lt;.001). For Black decedents, deaths were more likely to occur near foreclosures (RRV=9.01, SE=0.18, t-value =11.92, <em>p</em>&lt;.001), and places of worship (RRV= 2.51, SE=0.18, t-value = 11.92, <em>p</em>&lt;.001). For White decedents, deaths were more likely to occur in close proximity to hotels/motels (RRV=38.97, SE=0.39, t-value=9.30, <em>p</em>&lt;.001) foreclosures (RRV=2.57, SE=0.16, t-value =5.84, <em>p</em>&lt;.001), restaurants (RRV=2.52, SE=0.17, t-value=5.33, <em>p</em>&lt;.001) and, auto painting/repair shops (RRV=0.04, SE=0.18, t-value =3.39, <em>p</em>&lt;.001).</div></div><div><h3>Conclusion</h3><div>These findings suggest that places of worship, the hospitality industry, and housing authorities may be physical features of the environment that reflect social conditions that are conducive to overdose. The scaling up of harm reduction strategies could be enhanced by targeting places where features are co-located.</div></div>","PeriodicalId":48364,"journal":{"name":"International Journal of Drug Policy","volume":"134 ","pages":"Article 104611"},"PeriodicalIF":4.4,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining the association between trenbolone, psychological distress, and aggression among males who use anabolic-androgenic steroids 研究使用合成代谢雄性类固醇的男性群勃龙、心理压力和攻击性之间的关系
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2024-10-31 DOI: 10.1016/j.drugpo.2024.104636
Timothy Piatkowski , Dominique De Andrade , David Neumann , Calvert Tisdale , Matthew Dunn
Introduction: The link between anabolic-androgenic steroid (AAS) use and psychosocial effects such as aggression and violence is contentious. Few studies differentiate between types of AAS. This study focuses on trenbolone to assess its psychological risks and effects on aggression compared to other AAS. We hypothesised that there would be a positive relationship between trenbolone dosage and both psychological distress and aggression among people who use AAS. Methods: Using purposive and snowball sampling of people using AAS, we conducted an online survey to investigate the relationship between trenbolone use and other AAS use. Participants completed sections on demographics, trenbolone and other illicit drug use, the Kessler Psychological Distress Scale, and the Buss and Perry Aggression Questionnaire. Data were analysed using multinominal and multivariable regression. Results: The study included 282 males using AAS. Over 33% (n=93) reported currently using trenbolone, with 55.3% (n=156) of participants reporting having used trenbolone in the past, and 11.7% (n=33) reporting having never used trenbolone. Those who had never used trenbolone were not significantly different on age, height, weight, and BMI compared to those who had. After controlling for age and BMI, dose of trenbolone was significantly (p=0.045) associated with higher levels of verbal aggression. Conclusion: The study highlights trenbolone's association with increased verbal aggression among males using AAS, particularly at higher doses. Further research should continue to differentiate between AAS types and the accompanying health harms.
导言:合成代谢雄性类固醇(AAS)的使用与社会心理影响(如攻击和暴力)之间的联系存在争议。很少有研究区分 AAS 的类型。本研究以曲勃龙为重点,评估其与其他 AAS 相比对心理风险和攻击行为的影响。我们的假设是,在使用 AAS 的人群中,群勃龙剂量与心理困扰和攻击行为之间存在正相关关系。研究方法我们采用有目的的和滚雪球式的方法对使用 AAS 的人群进行了在线调查,以研究使用群勃龙和使用其他 AAS 之间的关系。参与者填写了有关人口统计学、使用群勃龙和其他非法药物、凯斯勒心理压力量表以及布斯和佩里攻击性问卷的部分。数据采用多项式和多变量回归法进行分析。研究结果研究对象包括 282 名使用 AAS 的男性。超过 33% 的参与者(人数=93)表示目前正在使用群勃龙,55.3% 的参与者(人数=156)表示过去曾使用过群勃龙,11.7% 的参与者(人数=33)表示从未使用过群勃龙。从未使用过曲勃龙的人与使用过的人相比,在年龄、身高、体重和体重指数方面没有明显差异。在控制了年龄和体重指数后,使用群勃龙的剂量与较高的言语攻击水平有显著相关性(p=0.045)。结论这项研究强调了群勃龙与使用合成动情激素(AAS)的男性言语攻击性增加有关,尤其是在剂量较大的情况下。进一步的研究应继续区分 AAS 类型及其对健康的危害。
{"title":"Examining the association between trenbolone, psychological distress, and aggression among males who use anabolic-androgenic steroids","authors":"Timothy Piatkowski ,&nbsp;Dominique De Andrade ,&nbsp;David Neumann ,&nbsp;Calvert Tisdale ,&nbsp;Matthew Dunn","doi":"10.1016/j.drugpo.2024.104636","DOIUrl":"10.1016/j.drugpo.2024.104636","url":null,"abstract":"<div><div><em>Introduction:</em> The link between anabolic-androgenic steroid (AAS) use and psychosocial effects such as aggression and violence is contentious. Few studies differentiate between types of AAS. This study focuses on trenbolone to assess its psychological risks and effects on aggression compared to other AAS. We hypothesised that there would be a positive relationship between trenbolone dosage and both psychological distress and aggression among people who use AAS. <em>Methods:</em> Using purposive and snowball sampling of people using AAS, we conducted an online survey to investigate the relationship between trenbolone use and other AAS use. Participants completed sections on demographics, trenbolone and other illicit drug use, the Kessler Psychological Distress Scale, and the Buss and Perry Aggression Questionnaire. Data were analysed using multinominal and multivariable regression. <em>Results:</em> The study included 282 males using AAS. Over 33% (<em>n</em>=93) reported currently using trenbolone, with 55.3% (<em>n</em>=156) of participants reporting having used trenbolone in the past, and 11.7% (<em>n</em>=33) reporting having never used trenbolone. Those who had never used trenbolone were not significantly different on age, height, weight, and BMI compared to those who had<em>.</em> After controlling for age and BMI, dose of trenbolone was significantly (<em>p</em>=0.045) associated with higher levels of verbal aggression. <em>Conclusion:</em> The study highlights trenbolone's association with increased verbal aggression among males using AAS, particularly at higher doses. Further research should continue to differentiate between AAS types and the accompanying health harms.</div></div>","PeriodicalId":48364,"journal":{"name":"International Journal of Drug Policy","volume":"134 ","pages":"Article 104636"},"PeriodicalIF":4.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142560770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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International Journal of Drug Policy
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