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Risk behaviors and prevalence of hepatitis B and C among people who inject drugs in Georgia: integrated bio-behavioral survey (IBBS) 格鲁吉亚注射吸毒者中乙型和丙型肝炎的危险行为和流行:综合生物行为调查(IBBS)
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-12 DOI: 10.1016/j.drugpo.2026.105177
Kanchelashvili Giorgi , Butsashvili Maia , Kochlamazashvili Marika , Gulbiani Lasha , Abashidze Giga , Kamkamidze Tina , Abzianidze Tinatin , Adamia Sopio , Chelidze Nikoloz , Stvilia Ketevan , Kamkamidze George

Introduction

Injection drug use (IDU) poses significant public health risks, including the transmission of blood-borne infections such as hepatitis B (HBV) and hepatitis C (HCV). This study aims to evaluate the prevalence of risk behaviors associated with IDU and the prevalence of HBV and HCV among people who inject drugs (PWID) in Georgia.

Methods

A cross-sectional study was conducted in seven cities of Georgia in 2022, involving 2005 PWID aged ≥18 years. Participants were recruited using respondent-driven sampling. Data were collected through face-to-face interviews and blood samples were collected for HCV/HBV testing.

Results

The majority of study participants (98.6%) were males, 63.2% were older than 40 years, and 51.3% had a history of imprisonment. 24.4% reported using a needle/syringe previously used by someone else. HCV seropositivity was found in 58.1% of respondents, with 32.1% of anti-HCV positive individuals testing positive for HCV RNA. HBV surface antigen was detected in 2.5%. Only 7.5% reported being vaccinated for hepatitis B and 27.8% expressed willingness to be vaccinated. 33.9% had HCV treatment history. HCV prevalence was significantly higher among males, older PWID, those with a history of incarceration and history of sharing needles used by others.

Conclusion

Our findings highlight the high prevalence of HCV and low HBV vaccination rates among PWID in Georgia, emphasizing the need for strengthened harm reduction strategies. Expanding sterile injection access, integrating HBV vaccination, and removing structural barriers are key to improving prevention and testing efforts and linkage to care.
注射药物使用(IDU)构成重大的公共卫生风险,包括乙型肝炎(HBV)和丙型肝炎(HCV)等血源性感染的传播。本研究旨在评估格鲁吉亚注射吸毒者(PWID)中与IDU相关的危险行为的流行程度以及HBV和HCV的流行程度。方法于2022年在佐治亚州7个城市进行横断面研究,纳入2005名年龄≥18岁的PWID患者。参与者是采用受访者驱动的抽样方式招募的。通过面对面访谈收集数据,并采集血样进行HCV/HBV检测。结果98.6%的研究对象为男性,63.2%的研究对象年龄在40岁以上,51.3%的研究对象有入狱史。24.4%报告使用了别人以前使用过的针头/注射器。在58.1%的应答者中发现HCV血清阳性,32.1%的抗HCV阳性个体检测HCV RNA阳性。HBV表面抗原检测率为2.5%。只有7.5%的人报告接种了乙肝疫苗,27.8%的人表示愿意接种。33.9%有丙型肝炎治疗史。HCV患病率在男性、老年PWID患者、有监禁史和与他人共用针头史的人群中明显较高。结论:我们的研究结果强调了格鲁吉亚PWID中HCV的高患病率和HBV的低疫苗接种率,强调了加强减少危害策略的必要性。扩大无菌注射、整合乙肝疫苗接种和消除结构性障碍是改善预防和检测工作以及与护理联系的关键。
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引用次数: 0
A nationally representative repeated cross-sectional study of 10-year substance use trends among culturally and linguistically diverse Australians 一项具有全国代表性的重复横断面研究,研究了文化和语言多样化的澳大利亚人10年来的物质使用趋势。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-11 DOI: 10.1016/j.drugpo.2026.105179
Yan Yee Lee , Tianze Sun , Jason P. Connor , Coral Gartner , Germaine Lai , Heena Akbar , Carmen C.W. Lim

Aim

To estimate the absolute and relative changes in prevalence of tobacco, e-cigarette, alcohol, and illicit substance use over the past decade among Culturally and Linguistically Diverse (CALD) and non-CALD populations in Australia from 2013 to 2022/23.

Method

Data were drawn from four waves of the National Drug Strategy Household Survey (NDSHS), comprising of 91, 282 respondents (2013: n = 23, 855; 2016: n = 23, 749; 2019: n = 22, 015; 2022/23: n = 21, 663). CALD status (22.5% of weighted sample) was defined as being born outside Australia/New Zealand/United Kingdom and/or speaking a language other than English at home. Analyses calculated weighted prevalence estimates and absolute and relative changes in prevalence between 2013 and 2022/23 with 99% CI.

Findings

Between 2013 and 2022/2023, any tobacco product use declined significantly for both CALD (14.4% to 8.5%, 99%CI:8.0%, -3.7%) and non-CALD respondents (18.0% to 9.6%, 99%CI:9.6%, -7.3%). E-cigarette use (measured from 2016) increased in both populations, with CALD showing a 5-fold increase (0.8% to 4.8%; 99%CI: 2.7%, 5.2%) and non-CALD showing a 4.8-fold increase (1.3% to 7.5%; 99%CI: 5.5%, 7.0%). Risky alcohol use declined among CALD (23.2% to 13.1%, 99%CI:12.7%, -7.6%) and non-CALD respondents (43.2% to 33.9%, 99%CI:10.9%, -7.6%). Any illicit substance use remained stable among CALD respondents (10.3% to 9.0%; 99%CI: −3.2%, 0.8%) but increased among non-CALD respondents (16.0% to 18.4%; 99%CI: 1.2%, 3.8%).

Conclusions

In Australia, CALD individuals had lower prevalence of use of most tobacco products, e-cigarettes, alcohol, and illicit drugs than non-CALD individuals. Between 2013 and 2022/23, roll-your-own cigarette and waterpipe use remained stable among CALD individuals despite significant declines in non-CALD individuals. Both groups experienced steep rises in e-cigarette use between 2016 and 2022/23.
目的:估计2013年至2022/23年澳大利亚文化和语言多样性(CALD)和非CALD人群在过去十年中烟草、电子烟、酒精和非法药物使用的绝对和相对变化。方法:数据来自国家毒品战略住户调查(NDSHS)的四波调查,共91,282名受访者(2013年:n = 23,855; 2016年:n = 23,749; 2019年:n = 22,015; 2022/23年:n = 21,663)。CALD身份(占加权样本的22.5%)定义为出生在澳大利亚/新西兰/英国以外和/或在家中使用英语以外的语言。分析计算了2013年至2022/23年间加权患病率估计值以及患病率的绝对和相对变化,CI为99%。研究结果:2013年至2022/2023年期间,CALD(14.4%至8.5%,99%CI:8.0%, -3.7%)和非CALD受访者(18.0%至9.6%,99%CI:9.6%, -7.3%)的任何烟草制品使用量均显著下降。电子烟的使用(从2016年开始测量)在两个人群中都有所增加,CALD显示5倍增长(0.8%至4.8%;99%CI: 2.7%, 5.2%),非CALD显示4.8倍增长(1.3%至7.5%;99%CI: 5.5%, 7.0%)。高风险酒精使用在CALD受访者(23.2%至13.1%,99%CI:12.7%, -7.6%)和非CALD受访者(43.2%至33.9%,99%CI:10.9%, -7.6%)中有所下降。任何非法药物使用在CALD受访者中保持稳定(10.3%至9.0%;99%CI: -3.2%, 0.8%),但在非CALD受访者中增加(16.0%至18.4%;99%CI: 1.2%, 3.8%)。结论:在澳大利亚,与非CALD个体相比,CALD个体使用大多数烟草制品、电子烟、酒精和非法药物的流行率较低。在2013年至2022/23年期间,尽管非慢性阻塞性肺病患者的吸烟率显著下降,但慢性阻塞性肺病患者的卷烟和水烟使用量保持稳定。2016年至2022/23年期间,这两个群体的电子烟使用量都急剧上升。
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引用次数: 0
Breaking the cycle: addressing the evolving dynamic of violence associated with the European drug market 打破循环:处理与欧洲毒品市场有关的不断演变的暴力动态。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-11 DOI: 10.1016/j.drugpo.2026.105182
Teodora Groshkova, Alexander Söderholm, Marieke Liem, Kim Moeller, Seán Redmond, Paul Griffiths, Karin Svanberg, Célia Bobet, Liesbeth Vandam, Marica Ferri, Andrew Cunningham
Not applicable.
不适用。
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引用次数: 0
Outcomes and implications of British Columbia’s ‘drug decriminalization initiative’ for health-oriented drug policymaking 不列颠哥伦比亚省“药物非刑事化倡议”对面向健康的药物决策的结果和影响。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-06 DOI: 10.1016/j.drugpo.2026.105181
Benedikt Fischer , Didier Jutras-Aswad , Bernard Le Foll , Daniel T. Myran
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引用次数: 0
The global epidemiology of injecting drug use, HIV, viral hepatitis and tuberculosis among people who are incarcerated: a multistage systematic review. 被监禁者中注射吸毒、艾滋病毒、病毒性肝炎和结核病的全球流行病学:一项多阶段系统综述。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-05 DOI: 10.1016/j.drugpo.2025.105062
Louisa Degenhardt, Matthew Hickman, Frederick L Altice, Jason Grebely, Sophia Taylor, Michelle Lynch, Aleksa Kamenjas, Jack Marsden, Lucy T Tran, Paige Webb, Olivia Price, Christel Macdonald, Filipa Alves da Costa, Justin Berk, Anja Busse, Evan Cunningham, Colleen Daniels, Behzad Hajarizadeh, Linda Montanari, Luis Royuela, Keith Sabin, Jack Stone, Annette Verster, Peter Vickerman, Michael Farrell, Thomas Santo

Background: This global systematic review assesses the prevalence of injecting drug use (IDU) and key infectious diseases (HIV, hepatitis C virus [HCV], tuberculosis and hepatitis B virus [HBV]) among people who are incarcerated.

Methods: We conducted a systematic search of peer-reviewed (Medline, Embase, PsycINFO), internet, and grey literature databases, from January 2000 through 2nd June 2025 and engaged international experts and relevant agencies liaising with key agencies focused on incarcerated populations (WHO, UNODC, UNAIDS and EUDA). Data on study methods, size of incarcerated populations and demographic characteristics, and prevalence of IDU, HIV, HCV, HBV and tuberculosis among incarcerated populations were extracted. Meta-analyses pooled data where multiple estimates were available for a country; regional and global estimates were calculated, weighted by incarcerated population size. We present overall country, regional and global prevalence estimates for each variable examined, stratified by sex. We then estimated the ratio of IDU, HIV, HCV, HBV and tuberculosis prevalence among incarcerated populations compared to the general population.

Results: Of 75,755 screened documents, 2,968 were eligible for data extraction. There are approximately 11,322,000 people aged 15-64 years incarcerated globally with their incarceration rate being 221 per 100,000 (29 per 100,000 among females and 404 per 100,000 among males). Substantial variation in rates across countries and regions were observed with the highest regional rate being in North America. Globally, we estimate that 11·9% of people who are incarcerated have ever injected drugs (1,348,000; 95%CI 1,061,500-1,687,000), 51·4 times higher than the general population. We estimate that 3·7% (95%CI 2·5-5·4) of people who are incarcerated globally are living with HIV (25.1· times higher than the general population); 11·7% (95%CI 7·7-17·1) have current HCV infection (15·6 times higher); 4·4% (95%CI 2·4-7·7) have current HBV infection (2·2 times higher) and 2·5% (95%CI 1·5-3·8) have active tuberculosis (45·3 times higher than the general population). There is substantial variation geographically and among females and males.

Conclusion: The substantial concentration of people with multiple risks and comorbidities requires improved strategies to screen, evaluate, treat and prevent these adverse consequences, which is crucial for global control efforts.

Funding: Australian National Health and Medical Research Council.

背景:本全球系统综述评估了被监禁人员中注射吸毒(IDU)和主要传染病(HIV、丙型肝炎病毒(HCV)、结核病和乙型肝炎病毒(HBV))的流行情况。方法:从2000年1月至2025年6月2日,我们对同行评审(Medline、Embase、PsycINFO)、互联网和灰色文献数据库进行了系统检索,并与关注被监禁人群的主要机构(世卫组织、毒品和犯罪问题办公室、联合国艾滋病规划署和欧洲开发署)的国际专家和相关机构进行了联络。提取了有关研究方法、监禁人口规模和人口统计学特征的数据,以及监禁人口中IDU、HIV、HCV、HBV和结核病的患病率。荟萃分析汇集了一个国家的多个估计数据;计算了区域和全球的估计,并按监禁人口规模加权。我们给出了每个检查变量的总体国家、区域和全球患病率估计,并按性别分层。然后,与一般人群相比,我们估计了被监禁人群中IDU、HIV、HCV、HBV和结核病患病率的比例。结果:在筛选的75,755份文献中,有2,968份符合数据提取条件。全球大约有11,322,000名15-64岁的人被监禁,监禁率为每100,000人中有221人(女性为每100,000人中有29人,男性为每100,000人中有404人)。不同国家和地区的发病率差异很大,北美地区的发病率最高。在全球范围内,我们估计11.9%的被监禁者曾经注射过毒品(1348,000;95%CI 1,061,500-1,687,000),比一般人群高51.4倍。我们估计,全球被监禁的人中有3.7% (95%CI 2.5 - 5.4)是艾滋病毒携带者(比一般人群高25.1倍);11.7% (95%CI 7.7 - 17.1)目前感染HCV(高出15.6倍);4.4% (95%CI 2.4 - 7.7)的人目前感染HBV(高出2.2倍),2.5% (95%CI 1.5 - 3.8)的人患有活动性结核病(高出普通人群45.3倍)。在地域和男女之间存在很大差异。结论:具有多种风险和合并症的人群大量集中,需要改进筛查、评估、治疗和预防这些不良后果的策略,这对全球控制工作至关重要。资助:澳大利亚国家卫生和医学研究委员会。
{"title":"The global epidemiology of injecting drug use, HIV, viral hepatitis and tuberculosis among people who are incarcerated: a multistage systematic review.","authors":"Louisa Degenhardt, Matthew Hickman, Frederick L Altice, Jason Grebely, Sophia Taylor, Michelle Lynch, Aleksa Kamenjas, Jack Marsden, Lucy T Tran, Paige Webb, Olivia Price, Christel Macdonald, Filipa Alves da Costa, Justin Berk, Anja Busse, Evan Cunningham, Colleen Daniels, Behzad Hajarizadeh, Linda Montanari, Luis Royuela, Keith Sabin, Jack Stone, Annette Verster, Peter Vickerman, Michael Farrell, Thomas Santo","doi":"10.1016/j.drugpo.2025.105062","DOIUrl":"https://doi.org/10.1016/j.drugpo.2025.105062","url":null,"abstract":"<p><strong>Background: </strong>This global systematic review assesses the prevalence of injecting drug use (IDU) and key infectious diseases (HIV, hepatitis C virus [HCV], tuberculosis and hepatitis B virus [HBV]) among people who are incarcerated.</p><p><strong>Methods: </strong>We conducted a systematic search of peer-reviewed (Medline, Embase, PsycINFO), internet, and grey literature databases, from January 2000 through 2nd June 2025 and engaged international experts and relevant agencies liaising with key agencies focused on incarcerated populations (WHO, UNODC, UNAIDS and EUDA). Data on study methods, size of incarcerated populations and demographic characteristics, and prevalence of IDU, HIV, HCV, HBV and tuberculosis among incarcerated populations were extracted. Meta-analyses pooled data where multiple estimates were available for a country; regional and global estimates were calculated, weighted by incarcerated population size. We present overall country, regional and global prevalence estimates for each variable examined, stratified by sex. We then estimated the ratio of IDU, HIV, HCV, HBV and tuberculosis prevalence among incarcerated populations compared to the general population.</p><p><strong>Results: </strong>Of 75,755 screened documents, 2,968 were eligible for data extraction. There are approximately 11,322,000 people aged 15-64 years incarcerated globally with their incarceration rate being 221 per 100,000 (29 per 100,000 among females and 404 per 100,000 among males). Substantial variation in rates across countries and regions were observed with the highest regional rate being in North America. Globally, we estimate that 11·9% of people who are incarcerated have ever injected drugs (1,348,000; 95%CI 1,061,500-1,687,000), 51·4 times higher than the general population. We estimate that 3·7% (95%CI 2·5-5·4) of people who are incarcerated globally are living with HIV (25.1· times higher than the general population); 11·7% (95%CI 7·7-17·1) have current HCV infection (15·6 times higher); 4·4% (95%CI 2·4-7·7) have current HBV infection (2·2 times higher) and 2·5% (95%CI 1·5-3·8) have active tuberculosis (45·3 times higher than the general population). There is substantial variation geographically and among females and males.</p><p><strong>Conclusion: </strong>The substantial concentration of people with multiple risks and comorbidities requires improved strategies to screen, evaluate, treat and prevent these adverse consequences, which is crucial for global control efforts.</p><p><strong>Funding: </strong>Australian National Health and Medical Research Council.</p>","PeriodicalId":48364,"journal":{"name":"International Journal of Drug Policy","volume":" ","pages":"105062"},"PeriodicalIF":4.4,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global coverage of interventions for reduction of injecting drug use-related harm, HIV, viral hepatitis and tuberculosis in prisons and other carceral settings: A systematic review. 在监狱和其他监狱环境中减少注射吸毒相关伤害、艾滋病毒、病毒性肝炎和结核病的干预措施的全球覆盖面:系统审查。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-05 DOI: 10.1016/j.drugpo.2025.105069
Thomas Santo, Matthew Hickman, Frederick L Altice, Jason Grebely, Sophia Taylor, Michelle Lynch, Aleksa Kamenjaš, Jack Marsden, Lucy T Tran, Paige Webb, Olivia Price, Christel Macdonald, Linda Montanari, Luis Royuela, Anja Busse, Jack Stone, Filipa Alves da Costa, Justin Berk, Colleen Daniels, Evan Cunningham, Peter Vickerman, Behzad Hajarizadeh, Keith Sabin, Annette Verster, Michael Farrell, Louisa Degenhardt

Background: People who are incarcerated experience disproportionately high rates of injecting drug use and infectious disease, including HIV, viral hepatitis and tuberculosis. However, comprehensive global data regarding the availability of services that prevent and manage infectious disease, injecting drug use and related harms remain limited and outdated. We provide the first systematic review to comprehensively examine the availability and coverage of infectious disease prevention, treatment, and harm reduction services for incarcerated populations globally.

Methods: We conducted a systematic review of evidence for provision of opioid agonist treatment (OAT), needle syringe programs (NSPs), HIV testing and antiretroviral therapy (ART), hepatitis C virus (HCV) testing and direct-acting antiviral (DAA) treatment, tuberculosis screening and treatment, hepatitis B virus (HBV) testing, treatment, and vaccination in carceral settings. We searched from peer-reviewed and grey literature databases between 2000 and 2025 and used the most recent data available for each indicator.

Findings: OAT was documented in 59/207 countries (29 %), and NSPs in ten (5 %). HIV testing was documented in 86 countries (42 %) and ART in 79 countries (38 %). HCV testing was confirmed in 55 (27 %), with DAA treatment in 47 (23 %). HBV testing was identified in 51 countries (25 %), treatment in 36 (17 %), and vaccination in 41 (20 %). Tuberculosis screening was documented in 96 countries (46 %) and treatment in 81 (39 %). Fewer than 2 % (approximately 192,500) of the 11.3 million people incarcerated worldwide live in countries that offer OAT, NSPs, and treatment for HIV, HCV, HBV, and tuberculosis in at least one carceral facility. There is not a single country where incarcerated people have access to all such services in every facility. Programme level evidence was rarely available.

Interpretation: The global shortage of services that prevent and treat infectious disease and harms related to injecting drug use in carceral settings is a critical public health issue and, compared with community standards, a breach of human rights. This study underscores the urgent need for international collaboration and policy reform to scale up and stabilise services that address the health needs of incarcerated populations, ultimately improving health outcomes for both incarcerated populations and wider community.

Funding: Australian National Health and Medical Research Council.

背景:被监禁者注射吸毒和感染传染病(包括艾滋病毒、病毒性肝炎和结核病)的比例高得不成比例。然而,关于预防和管理传染病、注射吸毒及相关危害的服务提供情况的全面全球数据仍然有限且过时。我们提供了第一个系统综述,全面检查传染病预防、治疗和减少危害服务的可用性和覆盖范围,为全球监禁人口。方法:我们对阿片类激动剂治疗(OAT)、针头注射计划(NSPs)、艾滋病毒检测和抗逆转录病毒治疗(ART)、丙型肝炎病毒(HCV)检测和直接作用抗病毒(DAA)治疗、结核病筛查和治疗、乙型肝炎病毒(HBV)检测、治疗和在癌症环境中接种疫苗的证据进行了系统回顾。我们从2000年至2025年的同行评审和灰色文献数据库中进行了检索,并使用了每个指标的最新数据。研究结果:在59/207个国家(29%)有OAT记录,在10个国家(5%)有nsp记录。86个国家(42%)记录了艾滋病毒检测,79个国家(38%)记录了抗逆转录病毒治疗。55人(27%)接受HCV检测,47人(23%)接受DAA治疗。51个国家进行了HBV检测(25%),36个国家进行了治疗(17%),41个国家进行了疫苗接种(20%)。96个国家(46%)记录了结核病筛查,81个国家(39%)记录了结核病治疗。在全世界1130万被监禁者中,只有不到2%(约19.25万人)生活在提供OAT、NSPs以及在至少一所监狱设施中提供艾滋病毒、丙型肝炎病毒、乙型肝炎病毒和结核病治疗的国家。在任何一个国家,被监禁的人都可以在每个设施中获得所有这些服务。很少有方案层面的证据。解释:在监狱环境中预防和治疗传染病和与注射吸毒有关的危害的服务在全球范围内短缺,这是一个重大的公共卫生问题,与社区标准相比,这是对人权的侵犯。这项研究强调迫切需要进行国际合作和政策改革,以扩大和稳定解决被监禁人口健康需求的服务,最终改善被监禁人口和更广泛社区的健康结果。资助:澳大利亚国家卫生和医学研究委员会。
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引用次数: 0
Urban–rural disparities in oral nicotine pouch sales and flavors in the United States 美国口服尼古丁袋装销售和口味的城乡差异
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-03 DOI: 10.1016/j.drugpo.2026.105178
Lei Xu , Saber Feizy , Megan E Roberts , Ce Shang , Brittney Keller-Hamilton , Darren Mays , Shyanika W Rose , Yanyun He

Background

As oral nicotine pouches (ONPs) gain popularity in the United States, the extent to which product attributes, such as price and flavor, affect sales remains unclear. Examining urban–rural differences is particularly important given longstanding disparities in smokeless tobacco use and tobacco-related health outcomes across these settings, yet little is known about whether ONP sales and attribute preferences differ between urban and rural areas.

Objectives

This study aims to examine how ONP sales are associated with product attributes and sales locations (rural vs. urban), and whether the associations between sales and attributes differ by urban/rural locations.

Methods

We linked 2021 NielsenIQ retail sales data with the National Center for Health Statistics county-level urban/rural classifications. Flavors were grouped as implicit (marketed without explicit flavor names), mint/menthol, fruity, or other. Multivariable linear regression models were used by regressing ONP sales on product attributes, rural/urban status, and their interactions.

Results

In 2021, 88% of total ONP sales occurred in urban areas, compared with 12% in rural areas. ONP sales per 1000 population were 16% higher in rural than urban areas (p < 0.001). Compared to the sales of implicitly flavored ONPs, sales of mint/menthol, fruit, and other flavors were approximately 23-fold, 4-fold, and 7-fold higher, respectively. These flavor-related differences were less pronounced in rural counties than in urban counties. The price elasticity of demand was –0.66 (p < 0.001) in urban areas and –0.33 (p < 0.001) in rural areas.

Conclusions

ONP sales exhibit significant urban–rural disparities, with rural areas showing higher per capita sales overall, but urban areas showing stronger preferences for flavored products and greater price responsiveness. As a result, regulatory measures targeting flavors or pricing may have a greater impact in urban areas compared to rural ones.
随着口服尼古丁袋(ONPs)在美国越来越受欢迎,产品属性(如价格和口味)对销售的影响程度仍不清楚。鉴于无烟烟草使用和烟草相关健康结果在这些环境中的长期差异,检查城乡差异尤为重要,但人们对城乡地区的ONP销售和属性偏好是否存在差异知之甚少。本研究旨在研究ONP销售如何与产品属性和销售地点(农村与城市)相关联,以及销售和属性之间的关联是否因城市/农村地点而异。方法:我们将2021年尼尔森iq零售销售数据与国家卫生统计中心县级城市/农村分类相关联。口味分为隐性(没有明确的口味名称)、薄荷/薄荷醇、水果味或其他。采用多变量线性回归模型,将ONP销售额与产品属性、城乡状况及其相互作用进行回归。结果2021年,88%的ONP销售发生在城市地区,而农村地区为12%。农村每1000人的ONP销售额比城市地区高16% (p < 0.001)。与含蓄风味的onp相比,薄荷/薄荷醇、水果和其他口味的销售额分别高出约23倍、4倍和7倍。这些与口味相关的差异在农村县比在城市县不那么明显。城市地区需求的价格弹性为-0.66 (p < 0.001),农村地区为-0.33 (p < 0.001)。结论sonp销售表现出明显的城乡差异,农村地区的人均销售额总体较高,而城市地区对调味产品的偏好更强,价格反应能力更强。因此,针对口味或价格的监管措施在城市地区可能比在农村地区产生更大的影响。
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引用次数: 0
The emergence of problematic cannabis use as a network phenomenon 大麻使用问题的出现是一种网络现象。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-03 DOI: 10.1016/j.drugpo.2026.105175
Ronja Maria Järvelin
This study examines the emergence of problematic cannabis use as a dynamic, networked, and affective process. Drawing on Actor-Network Theory and Deleuze’s concept of affect, the analysis explores how shifting assemblages of human and non-human actors shape agency over time. The data consist of interviews with 23 participants and 16 written accounts submitted by individuals who self-identified their cannabis use as problematic. Through close reading of participants' narratives combined with network mapping, three phases were identified: opening, sustaining, and restricting networks. In the opening phase, network relations expand affective capacity by opening up new ways of thinking and extending the body’s range of movement in space. In the sustaining phase, these relations stabilize as cannabis becomes part of everyday routines that reproduce familiar rhythms rather than generating new openings. In the restricting phase, configurations involving specific material fixators (such as the bed, sofa, or digital devices) begin to limit spatial, emotional, and embodied possibilities, resulting in a contraction of affective capacity. These phases offer a heuristic framework for analyzing how problematic use stabilizes within socio-material assemblages, rather than as an outcome of isolated individual vulnerabilities. This perspective contributes to ongoing discussions in drug research by emphasizing relational dynamics and may inform treatment by identifying core networked actors that sustain or limit agency. Future research should examine how restricting networks may unravel and give rise to new affective landscapes.
本研究探讨了问题大麻使用的出现作为一个动态的,网络化的,和情感的过程。利用行动者网络理论和德勒兹的情感概念,分析探讨了人类和非人类行动者的变化组合如何随着时间的推移塑造代理。这些数据包括对23名参与者的采访和16份由自我认定大麻使用有问题的个人提交的书面报告。通过仔细阅读参与者的叙述并结合网络映射,我们确定了三个阶段:开放、维持和限制网络。在开放阶段,网络关系通过开辟新的思维方式和扩大身体在空间中的活动范围来扩展情感能力。在维持阶段,这些关系稳定下来,因为大麻成为日常生活的一部分,再现了熟悉的节奏,而不是产生新的开放。在限制阶段,涉及特定物质固定物(如床、沙发或数字设备)的配置开始限制空间、情感和具体化的可能性,导致情感能力的收缩。这些阶段提供了一个启发式框架,用于分析有问题的使用如何在社会物质组合中稳定下来,而不是作为孤立的个体脆弱性的结果。这一观点通过强调关系动力学有助于药物研究中正在进行的讨论,并可能通过确定维持或限制代理的核心网络参与者来告知治疗。未来的研究应该检查限制网络如何解开并产生新的情感景观。
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引用次数: 0
Barriers to evidence-based alcohol policies in France: Insights from interviews with parliament members 法国基于证据的酒精政策的障碍:来自议会成员采访的见解
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-01-30 DOI: 10.1016/j.drugpo.2026.105172
Ana Millot , François Topart , Janet Hoek , Karine Gallopel-Morvan

Background

In France, the evidence-based policies recommended by the World Health Organization SAFER program remain poorly implemented, despite relatively high levels of alcohol consumption and alcohol-related harms. To understand this paradox, we used Kingdon’s Multiple Streams Approach (MSA) as framework to analyze how members of the French parliament perceive alcohol and how alcohol industry and public health actors influence their decision-making.

Methods

We conducted twenty-five interviews with French deputies and senators from different political parties and regions. We built the interview guide following the three MSA streams: problem, policy, and political. We performed a thematic content analysis of the interview data using Nvivo to manage the data.

Results

The interviewed deputies and senators held ambivalent views on alcohol (problem stream): they acknowledged its health and social harms, but also emphasized its cultural and economic benefits. They supported low-evidence-based alcohol policies (e.g., education and targeted prevention) and showed limited support for Minimum Unit Pricing (MUP) policies (policy stream). Several arguments used by the alcohol industry against MUP emerged, including negative economic effects and illicit trade. The interviewed deputies and senators also reported more frequent interactions with alcohol industry actors than with public health actors (political stream).

Conclusion

In line with the MSA streams, our findings suggest that ambivalent framing of alcohol, weak support for evidence-based measures and a wine-favorable political environment may explain the weak alcohol control policies in France. Future research should include additional stakeholders to capture the full set of dynamics that contribute to policy inertia.
在法国,尽管酒精消费量和酒精相关危害相对较高,但世界卫生组织SAFER计划推荐的循证政策执行不力。为了理解这一悖论,我们使用金敦的多流方法(MSA)作为框架来分析法国议会成员如何看待酒精以及酒精行业和公共卫生行为者如何影响他们的决策。方法对来自不同政党和地区的法国众议员和参议员进行了25次访谈。我们根据三个MSA流构建了采访指南:问题、政策和政治。我们使用Nvivo对访谈数据进行了主题内容分析。结果受访的众议员和参议员对酒精(问题流)持有矛盾的看法:他们承认酒精对健康和社会的危害,但也强调它的文化和经济效益。他们支持低证据酒精政策(如教育和有针对性的预防),对最低单位定价(MUP)政策(政策流)的支持有限。酒业用来反对MUP的几个论点出现了,包括负面的经济影响和非法贸易。接受采访的众议员和参议员还报告说,他们与酒精行业行为者的互动比与公共卫生行为者的互动更频繁(政治流)。结论与MSA流一致,我们的研究结果表明,酒精的矛盾框架,对循证措施的弱支持以及有利于葡萄酒的政治环境可能解释了法国酒精控制政策的薄弱。未来的研究应包括更多的利益相关者,以捕捉导致政策惯性的全套动态。
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引用次数: 0
Are the data good enough? Assessing cocaine markets and indicators in The Netherlands, Denmark, and Sweden 数据足够好吗?评估荷兰、丹麦和瑞典的可卡因市场和指标
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-01-30 DOI: 10.1016/j.drugpo.2026.105176
Kim Moeller , Kamilla Haugen , Marieke Liem
The European cocaine market has undergone rapid transformations in recent years, with supply increasing and shifting geographically from southern to northwestern ports. These changes have implications for Northern Europe, as shorter distribution routes may affect prices, purity, and consumption. An unstable cocaine market may also increase risks of drug-related systemic violence.
This commentary assesses the utility of EU cocaine market indicators by examining trends in the Netherlands, Denmark and Sweden. Using data on price, purity and aggregate use reported to the European Union Drugs Agency (EUDA), we evaluate the quality and consistency of these indicators. We found that reporting for wholesale price and purity was highly inconsistent, while retail-level data were more complete, particularly from 2007 to 2023. Wastewater analysis provided a proxy for aggregate use.
Consistent with theoretical expectations, the markets in the three countries appear integrated, suggesting a supply route originating in the Netherlands and moving northward. Data deficiencies constrain research and policymaking at a time when a changing market increases risks of instability and violence.
近年来,欧洲可卡因市场发生了迅速变化,供应量增加,从地理位置上从南部港口转移到西北部港口。这些变化对北欧也有影响,因为较短的分销路线可能会影响价格、纯度和消费。不稳定的可卡因市场也可能增加与毒品有关的系统性暴力的风险。本评论通过审查荷兰、丹麦和瑞典的趋势来评估欧盟可卡因市场指标的效用。使用报告给欧盟药品管理局(EUDA)的价格、纯度和总使用量数据,我们评估了这些指标的质量和一致性。我们发现批发价格和纯度的报告高度不一致,而零售层面的数据更完整,特别是从2007年到2023年。废水分析提供了骨料利用的替代指标。与理论预期一致,这三个国家的市场似乎是一体化的,这表明一条源自荷兰并向北移动的供应路线。在不断变化的市场增加了不稳定和暴力风险之际,数据不足制约了研究和政策制定。
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引用次数: 0
期刊
International Journal of Drug Policy
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