Pub Date : 2025-04-06DOI: 10.1016/j.cpr.2025.102584
Siobhan M. O'Dean , Elizabeth Summerell , Eddie Harmon-Jones , J David Creswell , Thomas F. Denson
Dispositional mindfulness and mindfulness-based interventions have been linked to emotion regulation and may reduce anger and aggression. The present set of four meta-analyses examined and quantified correlational relationships between trait mindfulness, trait anger, and trait aggression, as well as the effects of experimental mindfulness-based interventions on anger and aggression. These meta-analyses contained data from 118 correlational (dispositional mindfulness) and experimental (mindfulness-based intervention) studies. For the subset of self-report correlational studies (kanger = 243, kaggression = 286), we found small-to-medium inverse relationships between dispositional mindfulness and both anger (r = −0.23, p < .001) and aggression (r = −0.19, p < .001). For experimental studies (kanger = 95, kaggression = 38), we found medium effects. Specifically, mindfulness-based interventions produced lower anger (d = −0.48, p < .001) and aggression (d = −0.61, p < .001) relative to the control groups. In sum, results suggest that mindfulness can curb angry and aggressive responses. Effect sizes for the interventions were largest in Asia. Studies with passive versus active control groups showed larger effect sizes. Effect sizes were largely equivalent for all populations studied (e.g., clinical, forensic, healthy adults, medical, students). Our meta-analytic findings suggest that mindfulness training may aid the effective regulation of anger and aggression for diverse populations. They also highlight the need for more rigorous control groups in future research.
性情正念和基于正念的干预与情绪调节有关，可能会减少愤怒和攻击性。本研究对特质正念、特质愤怒和特质攻击之间的相关关系以及基于正念的实验干预对愤怒和攻击的影响进行了检验和量化。这些荟萃分析包含118项相关研究（倾向正念）和实验研究（基于正念的干预）的数据。对于自我报告相关研究子集（kanger = 243, kaggression = 286），我们发现性格正念与愤怒之间存在中小型的负相关关系(r = - 0.23, p <；.001)和攻击性(r = - 0.19, p <；措施)。在实验研究中（kanger = 95, kaggression = 38），我们发现了中等效应。具体来说，基于正念的干预产生了更低的愤怒(d = - 0.48, p <；.001)和攻击性(d = - 0.61, p <；.001)。总之，研究结果表明，正念可以抑制愤怒和攻击性反应。干预措施的效应量在亚洲最大。被动对照组和主动对照组的研究显示出更大的效应值。所有研究人群（如临床、法医、健康成人、医学、学生）的效应量基本相同。我们的荟萃分析结果表明，正念训练可能有助于有效调节不同人群的愤怒和攻击性。他们还强调了在未来的研究中需要更严格的对照组。
{"title":"The associations and effects of mindfulness on anger and aggression: A meta-analytic review","authors":"Siobhan M. O'Dean , Elizabeth Summerell , Eddie Harmon-Jones , J David Creswell , Thomas F. Denson","doi":"10.1016/j.cpr.2025.102584","DOIUrl":"10.1016/j.cpr.2025.102584","url":null,"abstract":"<div><div>Dispositional mindfulness and mindfulness-based interventions have been linked to emotion regulation and may reduce anger and aggression. The present set of four meta-analyses examined and quantified correlational relationships between trait mindfulness, trait anger, and trait aggression, as well as the effects of experimental mindfulness-based interventions on anger and aggression. These meta-analyses contained data from 118 correlational (dispositional mindfulness) and experimental (mindfulness-based intervention) studies. For the subset of self-report correlational studies (<em>k</em><sub>anger</sub> = 243, <em>k</em><sub>aggression</sub> = 286), we found small-to-medium inverse relationships between dispositional mindfulness and both anger (<em>r</em> = −0.23, <em>p</em> < .001) and aggression (<em>r</em> = −0.19, <em>p</em> < .001). For experimental studies (<em>k</em><sub>anger</sub> = 95, <em>k</em><sub>aggression</sub> = 38), we found medium effects. Specifically, mindfulness-based interventions produced lower anger (<em>d</em> = −0.48, <em>p</em> < .001) and aggression (<em>d</em> = −0.61, <em>p</em> < .001) relative to the control groups. In sum, results suggest that mindfulness can curb angry and aggressive responses. Effect sizes for the interventions were largest in Asia. Studies with passive versus active control groups showed larger effect sizes. Effect sizes were largely equivalent for all populations studied (e.g., clinical, forensic, healthy adults, medical, students). Our meta-analytic findings suggest that mindfulness training may aid the effective regulation of anger and aggression for diverse populations. They also highlight the need for more rigorous control groups in future research.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"118 ","pages":"Article 102584"},"PeriodicalIF":13.7,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-02DOI: 10.1016/j.cpr.2025.102583
Victoria Pile, Stephen A. McIntyre, Jessica Richardson
{"title":"Response to Dr Rubinstein's commentary on McIntyre et al.'s (2024) systematic review of measures of mental imagery in emotional disorders","authors":"Victoria Pile, Stephen A. McIntyre, Jessica Richardson","doi":"10.1016/j.cpr.2025.102583","DOIUrl":"10.1016/j.cpr.2025.102583","url":null,"abstract":"","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"118 ","pages":"Article 102583"},"PeriodicalIF":13.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143819135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-02DOI: 10.1016/j.cpr.2025.102582
Dori Rubinstein
McIntyre et al. (2024) conducted a systematic review of mental imagery measures in emotional disorders using the COSMIN framework. While their work is a valuable contribution, several methodological issues raise concerns about the validity of their conclusions. This commentary discusses three key issues: (1) potential misinterpretation of scale construct definitions, (2) inconsistencies in study selection, and (3) limited consideration of the adaptive role of mental imagery. The Fantastic Reality Ability Measurement (FRAME) scale serves as an illustrative example. Addressing these limitations is crucial to ensuring that future systematic reviews accurately reflect the scope, function, and psychometric properties of mental imagery measures.
{"title":"Refining the evaluation of mental imagery measures: A commentary on McIntyre et al. (2024)","authors":"Dori Rubinstein","doi":"10.1016/j.cpr.2025.102582","DOIUrl":"10.1016/j.cpr.2025.102582","url":null,"abstract":"<div><div>McIntyre et al. (2024) conducted a systematic review of mental imagery measures in emotional disorders using the COSMIN framework. While their work is a valuable contribution, several methodological issues raise concerns about the validity of their conclusions. This commentary discusses three key issues: (1) potential misinterpretation of scale construct definitions, (2) inconsistencies in study selection, and (3) limited consideration of the adaptive role of mental imagery. The Fantastic Reality Ability Measurement (FRAME) scale serves as an illustrative example. Addressing these limitations is crucial to ensuring that future systematic reviews accurately reflect the scope, function, and psychometric properties of mental imagery measures.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"118 ","pages":"Article 102582"},"PeriodicalIF":13.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1016/j.cpr.2025.102580
Alex H.K. Wong
Extinction learning refers to a reduction in fear to a conditioned stimulus (CS) that previously signaled a threat, but now occurs without the expected threat. This mechanism is core to exposure-based treatments for anxiety-related disorders. Enhancing the generalization of extinction learning is crucial for improving treatment outcomes, as it helps reduce fear across a range of generalization stimuli (GSs) resembling the original fear-evoking CS. This narrative review identifies and covers three generalization of extinction learning models: 1) generalization of CS extinction learning, examining how extinction learning to the CS generalizes to novel GSs, 2) generalization of GS extinction learning, assessing how extinction learning to a GS generalizes to other novel GSs or the original CS, and 3) generalization of multiple stimuli extinction learning, where extinction learning involves multiple GSs (and sometimes the CS) and its effect on other novel stimuli. While extinction learning to the CS effectively generalizes to other stimuli, extinction learning to a GS or multiple GSs showed limited generalization to other novel GSs or the original CS. Since real-life exposure-based treatment rarely reproduces the CS, extinction learning involving only the GS(s) may better reflect clinical practice; poor generalization of GS(s) extinction learning may constitute another pathway of return of fear. This review also highlights various factors that influence generalization of extinction learning and call for future research to develop strategies for improving these processes, which can help inform exposure-based treatments.
{"title":"Spreading the reduction of fear: A narrative review of generalization of extinction learning in human fear conditioning","authors":"Alex H.K. Wong","doi":"10.1016/j.cpr.2025.102580","DOIUrl":"10.1016/j.cpr.2025.102580","url":null,"abstract":"<div><div>Extinction learning refers to a reduction in fear to a conditioned stimulus (CS) that previously signaled a threat, but now occurs without the expected threat. This mechanism is core to exposure-based treatments for anxiety-related disorders. Enhancing the generalization of extinction learning is crucial for improving treatment outcomes, as it helps reduce fear across a range of generalization stimuli (GSs) resembling the original fear-evoking CS. This narrative review identifies and covers three generalization of extinction learning models: 1) generalization of CS extinction learning, examining how extinction learning to the CS generalizes to novel GSs, 2) generalization of GS extinction learning, assessing how extinction learning to a GS generalizes to other novel GSs or the original CS, and 3) generalization of multiple stimuli extinction learning, where extinction learning involves multiple GSs (and sometimes the CS) and its effect on other novel stimuli. While extinction learning to the CS effectively generalizes to other stimuli, extinction learning to a GS or multiple GSs showed limited generalization to other novel GSs or the original CS. Since real-life exposure-based treatment rarely reproduces the CS, extinction learning involving only the GS(s) may better reflect clinical practice; poor generalization of GS(s) extinction learning may constitute another pathway of return of fear. This review also highlights various factors that influence generalization of extinction learning and call for future research to develop strategies for improving these processes, which can help inform exposure-based treatments.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"118 ","pages":"Article 102580"},"PeriodicalIF":13.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-30DOI: 10.1016/j.cpr.2025.102579
Jorge A. Cao-Noya, Cossette Canovas, Lorraine T. Benuto
The efficacy of posttraumatic stress disorder (PTSD) treatments might be hampered by individual differences. In order to maximize treatment efficacy in existing and newly developed interventions, controlling for individual variables is essential in treatment research. Given the marked physiological correlates of PTSD, biomarkers represent a promising solution. Throughout the PTSD literature, biomarkers have been used to assess treatment effects and predict treatment outcomes. However, the wide variety of biomarkers studied, along with several conflicting results, hinder researchers' abilities to comprehensively interpret the results reported. This systematic review of the literature aimed to identify and classify all biomarkers used to assess the efficacy of PTSD interventions and identify pre-treatment biomarkers able to predict treatment outcomes. Following PRISMA guidelines, we identified 70 studies that assessed biomarkers sensitivity to treatment effects and 25 that used biomarkers to predict treatment outcomes. Well-established treatments and newly developed protocols were included. The results were classified and interpreted by biomarker type. Indicators of neuroanatomical structures and functions were the most commonly studied biomarkers, followed by markers of cardiac activation and glucocorticoid analytes. Cardiac activation markers, and concretely heart rate reactivity to trauma cues, showed the most consistent findings, serving as a valuable method to assess treatment effects across different populations and treatment modalities. Other biomarkers showed promising trends both as predictors of treatment outcomes and measures of treatment efficacy, although essential methodological differences significantly impacted the comparison across studies.
{"title":"The use of biomarkers as measures of PTSD treatment efficacy and predictors of treatment outcomes: A systematic review","authors":"Jorge A. Cao-Noya, Cossette Canovas, Lorraine T. Benuto","doi":"10.1016/j.cpr.2025.102579","DOIUrl":"10.1016/j.cpr.2025.102579","url":null,"abstract":"<div><div>The efficacy of posttraumatic stress disorder (PTSD) treatments might be hampered by individual differences. In order to maximize treatment efficacy in existing and newly developed interventions, controlling for individual variables is essential in treatment research. Given the marked physiological correlates of PTSD, biomarkers represent a promising solution. Throughout the PTSD literature, biomarkers have been used to assess treatment effects and predict treatment outcomes. However, the wide variety of biomarkers studied, along with several conflicting results, hinder researchers' abilities to comprehensively interpret the results reported. This systematic review of the literature aimed to identify and classify all biomarkers used to assess the efficacy of PTSD interventions and identify pre-treatment biomarkers able to predict treatment outcomes. Following PRISMA guidelines, we identified 70 studies that assessed biomarkers sensitivity to treatment effects and 25 that used biomarkers to predict treatment outcomes. Well-established treatments and newly developed protocols were included. The results were classified and interpreted by biomarker type. Indicators of neuroanatomical structures and functions were the most commonly studied biomarkers, followed by markers of cardiac activation and glucocorticoid analytes. Cardiac activation markers, and concretely heart rate reactivity to trauma cues, showed the most consistent findings, serving as a valuable method to assess treatment effects across different populations and treatment modalities. Other biomarkers showed promising trends both as predictors of treatment outcomes and measures of treatment efficacy, although essential methodological differences significantly impacted the comparison across studies.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"118 ","pages":"Article 102579"},"PeriodicalIF":13.7,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-29DOI: 10.1016/j.cpr.2025.102581
Nora de Bode , Emese Kroon , Sharon R. Sznitman , Janna Cousijn
The use of medicinal cannabis to improve mental health is increasing globally, both in clinical settings and through self-medication. This involves a variety of products containing ∆9-tetrahydrocannabinol (THC), cannabidiol (CBD), THC + CBD combinations, or derivatives. This review provides an up-to-date overview of the positive and negative effects of medicinal cannabis on mental health diagnoses and related symptoms of the Diagnostic and Statistical Manual of Mental Disorders 5th Edition. Searches in PubMed, PsycInfo, Embase, and the Cochrane Library (October 2023 and July 2024) identified 18,341 studies, of which 49 controlled studies from 15 different countries were included. All studies focused on treatment-seeking participants using medicinal cannabis for (symptoms of) their mental health diagnosis. Included diagnoses were anxiety disorders, tic disorders, autism spectrum disorder, attention-deficit hyperactivity disorder, obsessive-compulsive disorders, anorexia nervosa, schizophrenia, psychosis, substance use disorders, insomnia, and bipolar disorders. Varying product compositions showed different effects. Most consistently, high doses of CBD were followed by some acute relief in anxiety, while CBD + THC combinations alleviated withdrawal in cannabis use disorder and improved sleep. In clinical trials, THC was associated most with dose-dependent adverse events and, in some cases, deterioration of primary study outcomes, e.g., in psychosis. In naturalistic studies, participants who used THC reported symptom improvement following usage. Risks of bias across studies were prevalent, and no study found long-lasting medicinal effects or improvement. Overall, medicinal cannabis may provide short-term relief for certain symptoms but is not a cure or without mental health risks.
{"title":"The differential effects of medicinal cannabis on mental health: A systematic review","authors":"Nora de Bode , Emese Kroon , Sharon R. Sznitman , Janna Cousijn","doi":"10.1016/j.cpr.2025.102581","DOIUrl":"10.1016/j.cpr.2025.102581","url":null,"abstract":"<div><div>The use of medicinal cannabis to improve mental health is increasing globally, both in clinical settings and through self-medication. This involves a variety of products containing ∆9-tetrahydrocannabinol (THC), cannabidiol (CBD), THC + CBD combinations, or derivatives. This review provides an up-to-date overview of the positive and negative effects of medicinal cannabis on mental health diagnoses and related symptoms of the Diagnostic and Statistical Manual of Mental Disorders 5th Edition. Searches in PubMed, PsycInfo, Embase, and the Cochrane Library (October 2023 and July 2024) identified 18,341 studies, of which 49 controlled studies from 15 different countries were included. All studies focused on treatment-seeking participants using medicinal cannabis for (symptoms of) their mental health diagnosis. Included diagnoses were anxiety disorders, tic disorders, autism spectrum disorder, attention-deficit hyperactivity disorder, obsessive-compulsive disorders, anorexia nervosa, schizophrenia, psychosis, substance use disorders, insomnia, and bipolar disorders. Varying product compositions showed different effects. Most consistently, high doses of CBD were followed by some acute relief in anxiety, while CBD + THC combinations alleviated withdrawal in cannabis use disorder and improved sleep. In clinical trials, THC was associated most with dose-dependent adverse events and, in some cases, deterioration of primary study outcomes, e.g., in psychosis. In naturalistic studies, participants who used THC reported symptom improvement following usage. Risks of bias across studies were prevalent, and no study found long-lasting medicinal effects or improvement. Overall, medicinal cannabis may provide short-term relief for certain symptoms but is not a cure or without mental health risks.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"118 ","pages":"Article 102581"},"PeriodicalIF":13.7,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143785751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-28DOI: 10.1016/j.cpr.2025.102569
Giulia Landi , Kenneth I. Pakenham , Zhangxuan Bao , Roberto Cattivelli , Elisabetta Crocetti , Eliana Tossani , Silvana Grandi
Serious parental physical or mental illness significantly increases the risk of adverse adjustment outcomes in adolescents and young adults. This systematic review and meta-analysis evaluates the efficacy of psychosocial interventions targeting this vulnerable group. Eligible randomized control trials (RCTs) were searched through the Medline, Web of Science, PsycINFO, PsycArticles, Cinahl, and ProQuest Dissertation and Theses databases. Young offspring outcomes included: psychological (including internalizing and externalizing problems), positive, and interpersonal adjustment. Thirty-one manuscripts reporting on twenty-seven independent RCTs, including 3590 adolescent and young adult offspring, met eligibility criteria. Most of the studies targeted adolescents with a mean age within ±1 SD of 12.17–16.33 years, with only one study directly targeting young adults. Three-quarters of studies included parental mental illness, and the remaining parental physical illness. Results highlighted a small post-intervention effect for psychological adjustment (d = 0.17,[0.05,0.29], p = .006), maintained at short-term (3–12 months) follow-up (d = 0.33 [0.12,0.54], p = .002), but not at long-term (15 months or longer) follow-up (d = −0.00 [−0.19,0.19], p = .98). A similar pattern emerged for internalizing problems, while for externalizing problems, no significant post-intervention effect was detected. Results also showed a small post-intervention effect for positive adjustment (d = 0.36,[0.10,0.61], p = .006), which increased to a medium effect at short-term follow-up (d = 0.62,[0.15,1.09], p = .010). Post-intervention effects were not present for interpersonal adjustment. Intervention duration moderated effects on post-intervention outcomes, while intervention setting and gender balance moderated outcomes at follow-ups. Psychosocial interventions for young offspring of parents with serious illnesses appear effective in improving psychological and positive outcomes with small-to-moderate effects at post-intervention and short-term follow-up.
严重的父母身体或精神疾病显著增加青少年和年轻人不良适应结果的风险。本系统综述和荟萃分析评估了针对这一弱势群体的社会心理干预的效果。通过Medline、Web of Science、PsycINFO、PsycArticles、Cinahl和ProQuest Dissertation and Theses数据库检索符合条件的随机对照试验（RCTs）。年轻后代的结果包括：心理（包括内化和外化问题），积极和人际关系调整。31篇报道27项独立随机对照试验的论文符合入选标准，其中包括3590名青少年和年轻成人后代。大多数研究的对象是平均年龄在±1 SD范围内12.17-16.33岁的青少年，只有一项研究直接针对青壮年。四分之三的研究包括父母的精神疾病，其余的包括父母的身体疾病。结果显示，干预后心理调节的效果较小（d = 0.17,[0.05,0.29], p = 0.006），在短期（3-12个月）随访中保持（d = 0.33 [0.12,0.54], p = 0.002），但在长期（15个月或更长）随访中没有效果（d = - 0.00 [- 0.19,0.19], p = 0.98）。对于内化问题也出现了类似的模式，而对于外化问题，没有发现显著的干预后效果。结果还显示，干预后积极调整的效果较小（d = 0.36,[0.10,0.61], p = 0.006），在短期随访中增强为中等效果（d = 0.62,[0.15,1.09], p = 0.010）。干预后对人际适应没有影响。干预时间对干预后结果有调节作用，而干预设置和性别平衡对随访结果有调节作用。在干预后和短期随访中，对患有严重疾病的父母的年轻后代进行心理社会干预似乎在改善心理和积极结果方面有效，效果小到中等。
{"title":"Efficacy of psychosocial interventions for young offspring of parents with a serious physical or mental illness: Systematic review and meta-analysis","authors":"Giulia Landi , Kenneth I. Pakenham , Zhangxuan Bao , Roberto Cattivelli , Elisabetta Crocetti , Eliana Tossani , Silvana Grandi","doi":"10.1016/j.cpr.2025.102569","DOIUrl":"10.1016/j.cpr.2025.102569","url":null,"abstract":"<div><div>Serious parental physical or mental illness significantly increases the risk of adverse adjustment outcomes in adolescents and young adults. This systematic review and meta-analysis evaluates the efficacy of psychosocial interventions targeting this vulnerable group. Eligible randomized control trials (RCTs) were searched through the Medline, Web of Science, PsycINFO, PsycArticles, Cinahl, and ProQuest Dissertation and Theses databases. Young offspring outcomes included: psychological (including internalizing and externalizing problems), positive, and interpersonal adjustment. Thirty-one manuscripts reporting on twenty-seven independent RCTs, including 3590 adolescent and young adult offspring, met eligibility criteria. Most of the studies targeted adolescents with a mean age within ±1 SD of 12.17–16.33 years, with only one study directly targeting young adults. Three-quarters of studies included parental mental illness, and the remaining parental physical illness. Results highlighted a small post-intervention effect for psychological adjustment (<em>d</em> = 0.17,[0.05,0.29], <em>p</em> = .006), maintained at short-term (3–12 months) follow-up (<em>d</em> = 0.33 [0.12,0.54], <em>p</em> = .002), but not at long-term (15 months or longer) follow-up (<em>d</em> = −0.00 [−0.19,0.19], <em>p</em> = .98). A similar pattern emerged for internalizing problems, while for externalizing problems, no significant post-intervention effect was detected. Results also showed a small post-intervention effect for positive adjustment (<em>d</em> = 0.36,[0.10,0.61], <em>p</em> = .006), which increased to a medium effect at short-term follow-up (<em>d</em> = 0.62,[0.15,1.09], <em>p</em> = .010). Post-intervention effects were not present for interpersonal adjustment. Intervention duration moderated effects on post-intervention outcomes, while intervention setting and gender balance moderated outcomes at follow-ups. Psychosocial interventions for young offspring of parents with serious illnesses appear effective in improving psychological and positive outcomes with small-to-moderate effects at post-intervention and short-term follow-up.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"118 ","pages":"Article 102569"},"PeriodicalIF":13.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-27DOI: 10.1016/j.cpr.2025.102570
Juan Martín Gómez Penedo , Manuel Meglio , Christoph Flückiger , Frederik J. Wienicke , Jasmijn Breunese , Marco Menchetti , Paola Rucci , Robert Johansson , Joel M. Town , Allan A. Abbass , Peter Lilliengren , R. Michael Bagby , Lena C. Quilty , Lotte H.J.M. Lemmens , Suzanne C. van Bronswijk , Michael Barkham , William B. Stiles , Gillian E. Hardy , Peter Fonagy , Patrick Luyten , Ellen Driessen
Objectives
Interpersonal problems are a fundamental feature of depression, but study-level meta-analyses of their association with treatment outcome have been limited by heterogeneity in primary studies' analyses and reported results. We conducted a pre-registered individual participant data meta-analysis (IPD-MA) to examine this relationship for adult depression. This meta-analytic strategy can reduce variability by standardizing data analysis across primary studies.
Methods
We included studies examining the efficacy of five treatments for adult depression and assessing interpersonal problems at baseline. One-stage IPD-MA was conducted with three-level mixed models to determine whether baseline overall interpersonal distress, agency, and communion predicted depressive symptom level at post-treatment, 12-month, and 24-month follow-up. The moderating effect of treatment type was also investigated.
Results
Ten studies (including n = 1282 participants) met inclusion criteria. Only overall interpersonal distress was negatively related with outcomes at post-treatment (γ = 0.11, CI95[0.06, 0.16], r = 0.11), 12-month follow-up (γ = 0.17, CI95[0.08, 0.25], r = 0.17), and 24-month follow-up (γ = 0.16, CI95[0.05, 0.26], r = 0.16), indicative of smaller effect sizes. The agency and communion dimensions were not significantly related to outcome. Treatment type did not significantly moderate interpersonal distress-outcome associations.
Discussion
Results show a small association between patient baseline overall interpersonal distress and subsequent depression treatment outcome in brief treatments for depression. Further studies might require to account for therapist effects.
Registration number osf.io/u46t7
目的人际关系问题是抑郁症的一个基本特征，但对其与治疗结果关联的研究水平荟萃分析受到了主要研究分析和报告结果异质性的限制。我们进行了一项预注册的个体参与者数据荟萃分析（IPD-MA）来检验成人抑郁症的这种关系。这种荟萃分析策略可以通过标准化跨主要研究的数据分析来减少可变性。方法我们纳入了五种治疗成人抑郁症的疗效的研究，并在基线时评估人际关系问题。一期IPD-MA采用三水平混合模型进行，以确定基线总体人际困扰、代理和交流是否预测治疗后、12个月和24个月随访时的抑郁症状水平。研究了不同处理方式的调节作用。结果10项研究（包括n = 1282名受试者）符合纳入标准。只有总体人际困扰与治疗后（γ = 0.11, CI95[0.06, 0.16], r = 0.11）、12个月随访（γ = 0.17, CI95[0.08, 0.25], r = 0.17）和24个月随访（γ = 0.16, CI95[0.05, 0.26], r = 0.16）的结果呈负相关，表明效应较小。代理和交流维度与结果没有显著相关。治疗类型不显著调节人际痛苦与预后的关联。讨论结果显示，在短暂的抑郁症治疗中，患者基线总体人际困扰与随后的抑郁症治疗结果之间存在很小的关联。进一步的研究可能需要考虑治疗师的影响。注册号为osf.io/u46t7
{"title":"Interpersonal problems as a predictor of treatment outcome in adult depression: An individual participant data meta-analysis","authors":"Juan Martín Gómez Penedo , Manuel Meglio , Christoph Flückiger , Frederik J. Wienicke , Jasmijn Breunese , Marco Menchetti , Paola Rucci , Robert Johansson , Joel M. Town , Allan A. Abbass , Peter Lilliengren , R. Michael Bagby , Lena C. Quilty , Lotte H.J.M. Lemmens , Suzanne C. van Bronswijk , Michael Barkham , William B. Stiles , Gillian E. Hardy , Peter Fonagy , Patrick Luyten , Ellen Driessen","doi":"10.1016/j.cpr.2025.102570","DOIUrl":"10.1016/j.cpr.2025.102570","url":null,"abstract":"<div><h3>Objectives</h3><div>Interpersonal problems are a fundamental feature of depression, but study-level meta-analyses of their association with treatment outcome have been limited by heterogeneity in primary studies' analyses and reported results. We conducted a pre-registered individual participant data meta-analysis (IPD-MA) to examine this relationship for adult depression. This meta-analytic strategy can reduce variability by standardizing data analysis across primary studies.</div></div><div><h3>Methods</h3><div>We included studies examining the efficacy of five treatments for adult depression and assessing interpersonal problems at baseline. One-stage IPD-MA was conducted with three-level mixed models to determine whether baseline overall interpersonal distress, agency, and communion predicted depressive symptom level at post-treatment, 12-month, and 24-month follow-up. The moderating effect of treatment type was also investigated.</div></div><div><h3>Results</h3><div>Ten studies (including <em>n</em> = 1282 participants) met inclusion criteria. Only overall interpersonal distress was negatively related with outcomes at post-treatment (<em>γ</em> = 0.11, CI<sub>95</sub>[0.06, 0.16], <em>r</em> = 0.11), 12-month follow-up (<em>γ</em> = 0.17, CI<sub>95</sub>[0.08, 0.25], <em>r</em> = 0.17), and 24-month follow-up (<em>γ</em> = 0.16, CI<sub>95</sub>[0.05, 0.26], <em>r</em> = 0.16), indicative of smaller effect sizes. The agency and communion dimensions were not significantly related to outcome. Treatment type did not significantly moderate interpersonal distress-outcome associations.</div></div><div><h3>Discussion</h3><div>Results show a small association between patient baseline overall interpersonal distress and subsequent depression treatment outcome in brief treatments for depression. Further studies might require to account for therapist effects.</div><div>Registration number osf.io/u46t7</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"118 ","pages":"Article 102570"},"PeriodicalIF":13.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143734596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-26DOI: 10.1016/j.cpr.2025.102571
Urdur Njardvik , Gro Janne Wergeland , Eili N. Riise , Dagmar Kr. Hannesdottir , Lars-Göran Öst
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with estimated worldwide prevalence of 7.2 % in children and adolescents. Comorbidity of psychiatric disorders is considered common in ADHD and has been found to contribute to poorer prognosis. Despite decades of research, the actual prevalence of comorbid psychiatric disorders in children and adolescents with ADHD is unclear. The purpose of this systematic review and meta-analysis was to investigate the prevalence of comorbid disorders in children and adolescents with ADHD. Embase OVID, Ovid MEDLINE and PsycINFO were systematically searched for eligible studies published up to February 2025. In total 121 studies involving 39,894 children and adolescents with ADHD diagnosis were included. The most common comorbid disorders were Oppositional Defiant Disorder (34.7 %), Behavior Disorders (30.7 %), Anxiety Disorders (18.4 %), Specific phobias (11.0 %), Enuresis (10.8 %), and Conduct Disorder (CD) (10.7 %). All individual disorders studied had a higher prevalence among children and adolescents with ADHD than in the general population. Few gender differences were found; higher prevalence of CD among boys and higher of OCD in girls. The findings indicate that comorbid psychiatric disorders are highly prevalent in children and adolescents with ADHD and must be considered in both assessment and treatment of ADHD.
{"title":"Psychiatric comorbidity in children and adolescents with ADHD: A systematic review and meta-analysis","authors":"Urdur Njardvik , Gro Janne Wergeland , Eili N. Riise , Dagmar Kr. Hannesdottir , Lars-Göran Öst","doi":"10.1016/j.cpr.2025.102571","DOIUrl":"10.1016/j.cpr.2025.102571","url":null,"abstract":"<div><div>Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with estimated worldwide prevalence of 7.2 % in children and adolescents. Comorbidity of psychiatric disorders is considered common in ADHD and has been found to contribute to poorer prognosis. Despite decades of research, the actual prevalence of comorbid psychiatric disorders in children and adolescents with ADHD is unclear. The purpose of this systematic review and meta-analysis was to investigate the prevalence of comorbid disorders in children and adolescents with ADHD. Embase OVID, Ovid MEDLINE and PsycINFO were systematically searched for eligible studies published up to February 2025. In total 121 studies involving 39,894 children and adolescents with ADHD diagnosis were included. The most common comorbid disorders were Oppositional Defiant Disorder (34.7 %), Behavior Disorders (30.7 %), Anxiety Disorders (18.4 %), Specific phobias (11.0 %), Enuresis (10.8 %), and Conduct Disorder (CD) (10.7 %). All individual disorders studied had a higher prevalence among children and adolescents with ADHD than in the general population. Few gender differences were found; higher prevalence of CD among boys and higher of OCD in girls. The findings indicate that comorbid psychiatric disorders are highly prevalent in children and adolescents with ADHD and must be considered in both assessment and treatment of ADHD.</div><div>PROSPERO registration: ID CRD42022359965.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"118 ","pages":"Article 102571"},"PeriodicalIF":13.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143838518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-06DOI: 10.1016/j.cpr.2025.102568
Serena Shukla , Ryan J. Smith , Anastasiia Burik , Dillon T. Browne , Hali Kil
Parents and youth often adjust to new cultures at differing rates, resulting in parent-child acculturation gaps. The acculturation-gap distress hypothesis theorizes that these differences may negatively impact the child, parent, and family; however, findings remain inconsistent. In this systematic review, we provide an up-to-date synthesis of existing research on the parent-child acculturation gap among immigrant families and whether and when children's social and psychological outcomes, parenting, and family functioning are impacted. Further, we build upon the differential nuances of the culture of the gap—receiving or heritage—that relate to these outcomes. A systematic search in five databases for relevant studies up to January 15, 2025 resulted in a total of 98 included records. Contrary to the acculturation gap-distress hypothesis, more than half of the included studies indicated no association between the receiving and heritage culture parent-child gap and child, parenting, or family outcomes. We discuss notable exceptions to this pattern, indicating when and how family and child outcomes may be implicated. We conclude with clinical and research recommendations to guide future approaches for understanding the relevance of parent-child acculturation gaps for family and child outcomes.
{"title":"When and how do parent-child acculturation gaps matter? A systematic review and recommendations for research and practice","authors":"Serena Shukla , Ryan J. Smith , Anastasiia Burik , Dillon T. Browne , Hali Kil","doi":"10.1016/j.cpr.2025.102568","DOIUrl":"10.1016/j.cpr.2025.102568","url":null,"abstract":"<div><div>Parents and youth often adjust to new cultures at differing rates, resulting in parent-child acculturation gaps. The acculturation-gap distress hypothesis theorizes that these differences may negatively impact the child, parent, and family; however, findings remain inconsistent. In this systematic review, we provide an up-to-date synthesis of existing research on the parent-child acculturation gap among immigrant families and whether and when children's social and psychological outcomes, parenting, and family functioning are impacted. Further, we build upon the differential nuances of the culture of the gap—receiving or heritage—that relate to these outcomes. A systematic search in five databases for relevant studies up to January 15, 2025 resulted in a total of 98 included records. Contrary to the acculturation gap-distress hypothesis, more than half of the included studies indicated no association between the receiving and heritage culture parent-child gap and child, parenting, or family outcomes. We discuss notable exceptions to this pattern, indicating when and how family and child outcomes may be implicated. We conclude with clinical and research recommendations to guide future approaches for understanding the relevance of parent-child acculturation gaps for family and child outcomes.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"117 ","pages":"Article 102568"},"PeriodicalIF":13.7,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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